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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs75466358
log Bayes Factor = 21.4617
Chromosome 14   position 98,107,800  (GRCh37) Explore rs75466358 on Ensembl!
Variant rs75466358 is part of Cluster X0259

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.990 0.010 0.000
Chapter VIII Diseases of the ear and mastoid process
0.989 0.011 0.000
J30-J39 Other diseases of upper respiratory tract
0.987 0.013 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.983 0.017 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.981 0.019 0.000
J34 Other disorders of nose and nasal sinuses
0.979 0.021 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.978 0.022 0.000
J34.2 Deviated nasal septum
0.971 0.029 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.968 0.032 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.967 0.033 0.000
G40-G47 Episodic and paroxysmal disorders
0.964 0.036 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.962 0.038 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.957 0.043 0.000
C78.7 Secondary malignant neoplasm of liver
0.955 0.045 0.000
C64-C68 Malignant neoplasms of urinary tract
0.952 0.048 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.945 0.055 0.000
D60-D64 Aplastic and other anaemias
0.945 0.055 0.000
D00-D09 In situ neoplasms
0.942 0.058 0.000
D70 Agranulocytosis
0.941 0.059 0.000
Chapter V Mental and behavioural disorders
0.936 0.064 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.934 0.066 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.932 0.068 0.000
C83.3 Large cell (diffuse)
0.931 0.069 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.927 0.073 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.924 0.076 0.000
F30-F39 Mood [affective] disorders
0.924 0.076 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.923 0.077 0.000
D10-D36 Benign neoplasms
0.921 0.079 0.000
H90-H95 Other disorders of ear
0.921 0.079 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.920 0.080 0.000
G30-G32 Other degenerative diseases of the nervous system
0.915 0.085 0.000
D64 Other anaemias
0.914 0.086 0.000
S70-S79 Injuries to the hip and thigh
0.913 0.087 0.000
D22 Melanocytic naevi
0.912 0.088 0.000
G90-G99 Other disorders of the nervous system
0.909 0.091 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.906 0.094 0.000
H65-H75 Diseases of middle ear and mastoid
0.905 0.095 0.000
S00-S09 Injuries to the head
0.901 0.099 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.898 0.102 0.000
M86-M90 Other osteopathies
0.897 0.103 0.000
D64.9 Anaemia, unspecified
0.892 0.108 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.889 0.111 0.000
O60-O75 Complications of labour and delivery
0.888 0.112 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.887 0.113 0.000
T81 Complications of procedures, not elsewhere classified
0.887 0.113 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.881 0.119 0.000
Chapter I Certain infectious and parasitic diseases
0.881 0.119 0.000
F32 Depressive episode
0.881 0.119 0.000
S80-S89 Injuries to the knee and lower leg
0.878 0.122 0.000
M20-M25 Other joint disorders
0.876 0.124 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.875 0.125 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.871 0.129 0.000
J60-J70 Lung diseases due to external agents
0.869 0.131 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.867 0.133 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.866 0.134 0.000
D22.4 Melanocytic naevi of scalp and neck
0.865 0.135 0.000
X60-X84 Intentional self-harm
0.862 0.138 0.000
O47 False labour
0.861 0.139 0.000
A30-A49 Other bacterial diseases
0.852 0.148 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.852 0.148 0.000
S20-S29 Injuries to the thorax
0.850 0.150 0.000
J30 Vasomotor and allergic rhinitis
0.849 0.151 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.847 0.153 0.000
C51-C58 Malignant neoplasms of female genital organs
0.847 0.153 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.845 0.155 0.000
C77.0 Lymph nodes of head, face and neck
0.845 0.155 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.841 0.159 0.000
D03 Melanoma in situ
0.840 0.160 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.837 0.163 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.837 0.163 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.837 0.163 0.000
J95-J99 Other diseases of the respiratory system
0.836 0.164 0.000
H80-H83 Diseases of inner ear
0.835 0.165 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.834 0.166 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.834 0.166 0.000
D25 Leiomyoma of uterus
0.832 0.168 0.000
O80-O84 Delivery
0.831 0.169 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.830 0.170 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.830 0.170 0.000
J34.3 Hypertrophy of nasal turbinates
0.830 0.170 0.000
G40 Epilepsy
0.828 0.172 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.827 0.173 0.000
H93 Other disorders of ear, not elsewhere classified
0.826 0.174 0.000
M24 Other specific joint derangements
0.825 0.175 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.825 0.175 0.000
S40-S49 Injuries to the shoulder and upper arm
0.823 0.177 0.000
F33 Recurrent depressive disorder
0.822 0.178 0.000
O85-O92 Complications predominantly related to the puerperium
0.822 0.178 0.000
D05 Carcinoma in situ of breast
0.819 0.180 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.818 0.182 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.818 0.182 0.000
J20-J22 Other acute lower respiratory infections
0.817 0.183 0.000
J33 Nasal polyp
0.816 0.184 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.816 0.184 0.000
S02 Fracture of skull and facial bones
0.815 0.185 0.000
G91 Hydrocephalus
0.815 0.185 0.000
A41 Other septicaemia
0.815 0.185 0.000
O70 Perineal laceration during delivery
0.813 0.187 0.000
O48 Prolonged pregnancy
0.813 0.187 0.000
S72 Fracture of femur
0.812 0.188 0.000
D75 Other diseases of blood and blood-forming organs
0.811 0.189 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.810 0.190 0.000
G45.4 Transient global amnesia
0.809 0.191 0.000
T79-T79 Certain early complications of trauma
0.807 0.193 0.000
M80-M85 Disorders of bone density and structure
0.806 0.194 0.000
J09-J18 Influenza and pneumonia
0.806 0.194 0.000
H72 Perforation of tympanic membrane
0.805 0.195 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.804 0.196 0.000
H74 Other disorders of middle ear and mastoid
0.802 0.198 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.801 0.199 0.000
A41.9 Septicaemia, unspecified
0.799 0.201 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.799 0.201 0.000
T93 Sequelae of injuries of lower limb
0.798 0.202 0.000
D10 Benign neoplasm of mouth and pharynx
0.798 0.202 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.797 0.203 0.000
F32.9 Depressive episode, unspecified
0.796 0.204 0.000
T87 Complications peculiar to reattachment and amputation
0.796 0.204 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.796 0.204 0.000
C90.0 Multiple myeloma
0.794 0.206 0.000
M05-M14 Inflammatory polyarthropathies
0.793 0.207 0.000
C91 Lymphoid leukaemia
0.793 0.207 0.000
M87 Osteonecrosis
0.792 0.208 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.789 0.211 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.789 0.211 0.000
H60-H62 Diseases of external ear
0.788 0.212 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.787 0.213 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.787 0.213 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.786 0.214 0.000
J90-J94 Other diseases of pleura
0.785 0.215 0.000
C78.0 Secondary malignant neoplasm of lung
0.784 0.216 0.000
D25.9 Leiomyoma of uterus, unspecified
0.784 0.216 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.783 0.217 0.000
H91 Other hearing loss
0.782 0.218 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.781 0.219 0.000
F31 Bipolar affective disorder
0.779 0.221 0.000
G51 Facial nerve disorders
0.779 0.221 0.000
J69 Pneumonitis due to solids and liquids
0.778 0.222 0.000
C79.6 Secondary malignant neoplasm of ovary
0.777 0.223 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.776 0.224 0.000
M45-M49 Spondylopathies
0.774 0.226 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.774 0.226 0.000
Y86 Sequelae of other accidents
0.774 0.226 0.000
D80-D89 Certain disorders involving the immune mechanism
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.771 0.229 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.769 0.231 0.000
S10-S19 Injuries to the neck
0.768 0.232 0.000
M24.1 Other articular cartilage disorders
0.768 0.232 0.000
O70.0 First degree perineal laceration during delivery
0.768 0.232 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.766 0.234 0.000
S81 Open wound of lower leg
0.765 0.235 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.765 0.235 0.000
M90 Osteopathies in diseases classified elsewhere
0.765 0.235 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.762 0.237 0.000
T82.1 Mechanical complication of cardiac electronic device
0.762 0.238 0.000
G45.3 Amaurosis fugax
0.760 0.240 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.760 0.240 0.000
G70-G73 Diseases of myoneural junction and muscle
0.757 0.243 0.000
C77.8 Lymph nodes of multiple regions
0.757 0.243 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.757 0.243 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.756 0.244 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.756 0.244 0.000
D72 Other disorders of white blood cells
0.756 0.244 0.000
S70 Superficial injury of hip and thigh
0.755 0.245 0.000
J30.4 Allergic rhinitis, unspecified
0.755 0.245 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.752 0.248 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.751 0.248 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.751 0.249 0.000
M22 Disorders of patella
0.750 0.250 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.750 0.250 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.749 0.251 0.000
T90 Sequelae of injuries of head
0.749 0.251 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
Y84.2 Radiological procedure and radiotherapy
0.748 0.252 0.000
G91.9 Hydrocephalus, unspecified
0.748 0.252 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.746 0.254 0.000
O44 Placenta praevia
0.744 0.255 0.000
C54 Malignant neoplasm of corpus uteri
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.743 0.257 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.257 0.000
G51.0 Bell's palsy
0.742 0.258 0.000
W00-W19 Falls
0.741 0.259 0.000
Chapter XIV Diseases of the genitourinary system
0.739 0.261 0.000
X20-X29 Contact with venomous animals and plants
0.738 0.262 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.738 0.262 0.000
T51 Toxic effect of alcohol
0.738 0.262 0.000
D55-D59 Haemolytic anaemias
0.736 0.264 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.733 0.267 0.000
C77.2 Intra-abdominal lymph nodes
0.731 0.269 0.000
J35 Chronic diseases of tonsils and adenoids
0.731 0.269 0.000
S05 Injury of eye and orbit
0.730 0.270 0.000
H81 Disorders of vestibular function
0.730 0.270 0.000
C15-C26 Malignant neoplasms of digestive organs
0.729 0.271 0.000
H93.1 Tinnitus
0.728 0.272 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.727 0.273 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.726 0.274 0.000
D23 Other benign neoplasms of skin
0.726 0.274 0.000
C71 Malignant neoplasm of brain
0.726 0.274 0.000
D22.9 Melanocytic naevi, unspecified
0.725 0.275 0.000
C81 Hodgkin's disease
0.724 0.275 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.724 0.276 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.724 0.276 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.724 0.276 0.000
T86 Failure and rejection of transplanted organs and tissues
0.722 0.277 0.000
B25-B34 Other viral diseases
0.722 0.278 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.722 0.278 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.721 0.279 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
M40-M43 Deforming dorsopathies
0.721 0.279 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.721 0.279 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.719 0.281 0.000
T92 Sequelae of injuries of upper limb
0.718 0.282 0.000
H66 Suppurative and unspecified otitis media
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C85.1 B-cell lymphoma, unspecified
0.717 0.283 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.717 0.283 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.717 0.283 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.284 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.716 0.284 0.000
J39 Other diseases of upper respiratory tract
0.715 0.285 0.000
Y83.0 Surgical operation with transplant of whole organ
0.715 0.285 0.000
D10.3 Other and unspecified parts of mouth
0.714 0.286 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.714 0.286 0.000
J14 Pneumonia due to Haemophilus influenzae
0.714 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.714 0.286 0.000
J69.0 Pneumonitis due to food and vomit
0.713 0.287 0.000
O63 Long labour
0.713 0.287 0.000
S81.8 Open wound of other parts of lower leg
0.713 0.287 0.000
T98 Sequelae of other and unspecified effects of external causes
0.712 0.288 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.712 0.288 0.000
M15-M19 Arthrosis
0.712 0.288 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.288 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.711 0.289 0.000
O21 Excessive vomiting in pregnancy
0.711 0.289 0.000
O82 Single delivery by Caesarean section
0.710 0.289 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.710 0.290 0.000
H73 Other disorders of tympanic membrane
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.709 0.290 0.000
C95 Leukaemia of unspecified cell type
0.709 0.290 0.000
C94 Other leukaemias of specified cell type
0.709 0.290 0.000
C93 Monocytic leukaemia
0.709 0.290 0.000
C88 Malignant immunoproliferative diseases
0.709 0.290 0.000
C86 Other specified types of T/NK-cell lymphoma
0.709 0.290 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.709 0.290 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.709 0.291 0.000
N17-N19 Renal failure
0.709 0.291 0.000
S06 Intracranial injury
0.708 0.292 0.000
M87.9 Osteonecrosis, unspecified
0.708 0.292 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.708 0.292 0.000
J37 Chronic laryngitis and laryngotracheitis
0.708 0.292 0.000
S72.1 Pertrochanteric fracture
0.707 0.293 0.000
G95 Other diseases of spinal cord
0.706 0.294 0.000
G43 Migraine
0.706 0.294 0.000
J90 Pleural effusion, not elsewhere classified
0.706 0.294 0.000
D09 Carcinoma in situ of other and unspecified sites
0.705 0.295 0.000
Q60-Q64 Congenital malformations of the urinary system
0.702 0.298 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.702 0.298 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.702 0.298 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.701 0.299 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.701 0.299 0.000
S00 Superficial injury of head
0.701 0.299 0.000
S02.2 Fracture of nasal bones
0.700 0.300 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.699 0.301 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.699 0.301 0.000
N18 Chronic renal failure
0.699 0.301 0.000
C52 Malignant neoplasm of vagina
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.696 0.303 0.000
C83.0 Small cell (diffuse)
0.695 0.305 0.000
C45 Mesothelioma
0.695 0.305 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.694 0.306 0.000
D74 Methaemoglobinaemia
0.694 0.306 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.694 0.306 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.694 0.306 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.694 0.306 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.693 0.307 0.000
O41 Other disorders of amniotic fluid and membranes
0.693 0.307 0.000
H74.4 Polyp of middle ear
0.693 0.307 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.692 0.308 0.000
F33.9 Recurrent depressive disorder, unspecified
0.692 0.308 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.691 0.308 0.000
G41 Status epilepticus
0.691 0.308 0.000
T66-T78 Other and unspecified effects of external causes
0.691 0.309 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.690 0.310 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.690 0.310 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.690 0.310 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.690 0.310 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
T36 Poisoning by systemic antibiotics
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.310 0.000
J33.8 Other polyp of sinus
0.689 0.311 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.689 0.311 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.689 0.311 0.000
Y88 Sequelae of surgical and medical care as external cause
0.688 0.312 0.000
J22 Unspecified acute lower respiratory infection
0.688 0.312 0.000
C92 Myeloid leukaemia
0.687 0.313 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.687 0.313 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.686 0.314 0.000
C83.7 Burkitt's tumour
0.686 0.314 0.000
C83.6 Undifferentiated (diffuse)
0.686 0.314 0.000
C83.5 Lymphoblastic (diffuse)
0.686 0.314 0.000
C83.4 Immunoblastic (diffuse)
0.686 0.314 0.000
C83.2 Mixed small and large cell (diffuse)
0.686 0.314 0.000
C83.1 Small cleaved cell (diffuse)
0.686 0.314 0.000
D36 Benign neoplasm of other and unspecified sites
0.685 0.315 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.685 0.315 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.685 0.315 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.684 0.316 0.000
F80-F89 Disorders of psychological development
0.683 0.317 0.000
S29 Other and unspecified injuries of thorax
0.683 0.317 0.000
H91.9 Hearing loss, unspecified
0.683 0.317 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.683 0.317 0.000
C66 Malignant neoplasm of ureter
0.683 0.317 0.000
C65 Malignant neoplasm of renal pelvis
0.683 0.317 0.000
F20 Schizophrenia
0.683 0.317 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.683 0.317 0.000
G96 Other disorders of central nervous system
0.682 0.318 0.000
Y85 Sequelae of transport accidents
0.682 0.318 0.000
A46 Erysipelas
0.682 0.318 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.682 0.318 0.000
G81 Hemiplegia
0.681 0.318 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.319 0.000
C80 Malignant neoplasm without specification of site
0.680 0.319 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.680 0.320 0.000
Y84.6 Urinary catheterisation
0.679 0.321 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.679 0.321 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.678 0.322 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.678 0.322 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.678 0.322 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.678 0.322 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.678 0.322 0.000
G45.0 Vertebro-basilar artery syndrome
0.678 0.322 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.677 0.323 0.000
S32 Fracture of lumbar spine and pelvis
0.677 0.323 0.000
M07 Psoriatic and enteropathic arthropathies
0.677 0.323 0.000
C50-C50 Malignant neoplasm of breast
0.676 0.324 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
O34.1 Maternal care for tumour of corpus uteri
0.676 0.324 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.675 0.325 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.675 0.325 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.675 0.325 0.000
Chapter XXII Codes for special purposes
0.675 0.325 0.000
G30 Alzheimer's disease
0.675 0.325 0.000
G80 Infantile cerebral palsy
0.674 0.326 0.000
X78 Intentional self-harm by sharp object
0.674 0.326 0.000
D26 Other benign neoplasms of uterus
0.674 0.326 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.673 0.327 0.000
C77.4 Inguinal and lower limb lymph nodes
0.673 0.327 0.000
Chapter IX Diseases of the circulatory system
0.673 0.327 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.672 0.328 0.000
B65-B83 Helminthiases
0.672 0.328 0.000
O43 Placental disorders
0.671 0.328 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.671 0.329 0.000
F70-F79 Mental retardation
0.671 0.329 0.000
M90.7 Fracture of bone in neoplastic disease
0.670 0.329 0.000
H90 Conductive and sensorineural hearing loss
0.670 0.330 0.000
S72.3 Fracture of shaft of femur
0.670 0.330 0.000
D30 Benign neoplasm of urinary organs
0.670 0.330 0.000
H80 Otosclerosis
0.670 0.330 0.000
C54.1 Endometrium
0.669 0.330 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.669 0.331 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.669 0.331 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.669 0.331 0.000
T82.3 Mechanical complication of other vascular grafts
0.669 0.331 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.669 0.331 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.669 0.331 0.000
F99-F99 Unspecified mental disorder
0.669 0.331 0.000
D03.5 Melanoma in situ of trunk
0.667 0.332 0.000
S02.0 Fracture of vault of skull
0.667 0.332 0.000
C79.2 Secondary malignant neoplasm of skin
0.667 0.333 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.667 0.333 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.667 0.333 0.000
H93.9 Disorder of ear, unspecified
0.665 0.334 0.000
Y83.9 Surgical procedure, unspecified
0.665 0.335 0.000
A49 Bacterial infection of unspecified site
0.665 0.335 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.665 0.335 0.000
C15 Malignant neoplasm of oesophagus
0.665 0.335 0.000
O45 Premature separation of placenta [abruptio placentae]
0.665 0.335 0.000
O33 Maternal care for known or suspected disproportion
0.665 0.335 0.000
O31 Complications specific to multiple gestation
0.665 0.335 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.664 0.336 0.000
H81.1 Benign paroxysmal vertigo
0.663 0.336 0.000
E70-E90 Metabolic disorders
0.663 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.663 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.663 0.337 0.000
T91 Sequelae of injuries of neck and trunk
0.663 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.663 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.663 0.337 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.662 0.337 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.662 0.338 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.662 0.338 0.000
F38 Other mood [affective] disorders
0.662 0.338 0.000
F34 Persistent mood [affective] disorders
0.662 0.338 0.000
F30 Manic episode
0.662 0.338 0.000
F39 Unspecified mood [affective] disorder
0.662 0.338 0.000
J98 Other respiratory disorders
0.662 0.338 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.662 0.338 0.000
M50-M54 Other dorsopathies
0.662 0.338 0.000
M84 Disorders of continuity of bone
0.662 0.338 0.000
D50-D53 Nutritional anaemias
0.661 0.339 0.000
D04 Carcinoma in situ of skin
0.661 0.339 0.000
J33.9 Nasal polyp, unspecified
0.661 0.339 0.000
S41 Open wound of shoulder and upper arm
0.660 0.340 0.000
D31 Benign neoplasm of eye and adnexa
0.660 0.340 0.000
D29 Benign neoplasm of male genital organs
0.660 0.340 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.660 0.340 0.000
D19 Benign neoplasm of mesothelial tissue
0.660 0.340 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.660 0.340 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.660 0.340 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.660 0.340 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.658 0.342 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.657 0.343 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.657 0.343 0.000
S02.1 Fracture of base of skull
0.656 0.344 0.000
H92 Otalgia and effusion of ear
0.656 0.344 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.656 0.344 0.000
Q80-Q89 Other congenital malformations
0.655 0.345 0.000
D64.8 Other specified anaemias
0.655 0.345 0.000
D64.4 Congenital dyserythropoietic anaemia
0.655 0.345 0.000
D64.3 Other sideroblastic anaemias
0.655 0.345 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.655 0.345 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.655 0.345 0.000
D64.0 Hereditary sideroblastic anaemia
0.655 0.345 0.000
S79 Other and unspecified injuries of hip and thigh
0.655 0.345 0.000
S78 Traumatic amputation of hip and thigh
0.655 0.345 0.000
S77 Crushing injury of hip and thigh
0.655 0.345 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.655 0.345 0.000
S75 Injury of blood vessels at hip and thigh level
0.655 0.345 0.000
S74 Injury of nerves at hip and thigh level
0.655 0.345 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.655 0.345 0.000
S71 Open wound of hip and thigh
0.655 0.345 0.000
O40 Polyhydramnios
0.654 0.346 0.000
O62 Abnormalities of forces of labour
0.654 0.346 0.000
D22.0 Melanocytic naevi of lip
0.654 0.346 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.653 0.347 0.000
T87.6 Other and unspecified complications of amputation stump
0.653 0.347 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.652 0.348 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.652 0.348 0.000
G90 Disorders of autonomic nervous system
0.652 0.348 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.652 0.348 0.000
G92 Toxic encephalopathy
0.652 0.348 0.000
C91.1 Chronic lymphocytic leukaemia
0.652 0.348 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.652 0.348 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.652 0.348 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.651 0.348 0.000
J32 Chronic sinusitis
0.651 0.349 0.000
M86 Osteomyelitis
0.651 0.349 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.650 0.350 0.000
D11 Benign neoplasm of major salivary glands
0.650 0.350 0.000
D75.1 Secondary polycythaemia
0.650 0.350 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.649 0.351 0.000
H70 Mastoiditis and related conditions
0.649 0.351 0.000
H68 Eustachian salpingitis and obstruction
0.649 0.351 0.000
H67 Otitis media in diseases classified elsewhere
0.649 0.351 0.000
O00-O08 Pregnancy with abortive outcome
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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