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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116080128
log Bayes Factor = 12.1963
Chromosome 4   position 31,457,995  (GRCh37) Explore rs116080128 on Ensembl!
Variant rs116080128 is part of Cluster X0259

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.995 0.005 0.000
C15-C26 Malignant neoplasms of digestive organs
0.989 0.011 0.000
C79 Secondary malignant neoplasm of other sites
0.987 0.013 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.982 0.018 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.981 0.019 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
M45-M49 Spondylopathies
0.975 0.025 0.000
Chapter XIV Diseases of the genitourinary system
0.972 0.028 0.000
C20 Malignant neoplasm of rectum
0.967 0.033 0.000
N10-N16 Renal tubulo-interstitial diseases
0.960 0.040 0.000
M47 Spondylosis
0.958 0.042 0.000
M47.9 Spondylosis, unspecified
0.952 0.048 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.946 0.054 0.000
Y43 Primarily systemic agents
0.944 0.056 0.000
C78.7 Secondary malignant neoplasm of liver
0.944 0.056 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.943 0.057 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.942 0.058 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.941 0.059 0.000
M80-M85 Disorders of bone density and structure
0.934 0.066 0.000
Chapter VII Diseases of the eye and adnexa
0.932 0.068 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.929 0.071 0.000
W00-W19 Falls
0.926 0.074 0.000
C77.5 Intrapelvic lymph nodes
0.925 0.075 0.000
O70 Perineal laceration during delivery
0.922 0.078 0.000
N13 Obstructive and reflux uropathy
0.922 0.078 0.000
C78.0 Secondary malignant neoplasm of lung
0.918 0.082 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.915 0.085 0.000
C77.2 Intra-abdominal lymph nodes
0.913 0.087 0.000
S40-S49 Injuries to the shoulder and upper arm
0.910 0.090 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.910 0.090 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.909 0.091 0.000
N60-N64 Disorders of breast
0.909 0.091 0.000
C25 Malignant neoplasm of pancreas
0.906 0.094 0.000
M06 Other rheumatoid arthritis
0.901 0.099 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.899 0.101 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.899 0.101 0.000
G70-G73 Diseases of myoneural junction and muscle
0.898 0.102 0.000
H53-H54 Visual disturbances and blindness
0.897 0.103 0.000
Chapter I Certain infectious and parasitic diseases
0.896 0.104 0.000
Y43.3 Other antineoplastic drugs
0.894 0.106 0.000
C51-C58 Malignant neoplasms of female genital organs
0.892 0.108 0.000
N63 Unspecified lump in breast
0.891 0.109 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.889 0.111 0.000
Y52 Agents primarily affecting the cardiovascular system
0.889 0.111 0.000
C79.2 Secondary malignant neoplasm of skin
0.877 0.123 0.000
C77.9 Lymph node, unspecified
0.874 0.126 0.000
M84 Disorders of continuity of bone
0.873 0.127 0.000
M13 Other arthritis
0.864 0.136 0.000
G81 Hemiplegia
0.860 0.140 0.000
M10 Gout
0.857 0.143 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.855 0.145 0.000
H53 Visual disturbances
0.854 0.146 0.000
N00-N08 Glomerular diseases
0.854 0.146 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.850 0.150 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.849 0.151 0.000
C64-C68 Malignant neoplasms of urinary tract
0.848 0.152 0.000
O00-O08 Pregnancy with abortive outcome
0.847 0.153 0.000
S90-S99 Injuries to the ankle and foot
0.843 0.157 0.000
M06.9 Rheumatoid arthritis, unspecified
0.842 0.158 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.835 0.165 0.000
Y44 Agents primarily affecting blood constituents
0.831 0.169 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.830 0.170 0.000
G20-G26 Extrapyramidal and movement disorders
0.829 0.171 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.829 0.171 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.828 0.172 0.000
S42 Fracture of shoulder and upper arm
0.828 0.172 0.000
H53.8 Other visual disturbances
0.827 0.173 0.000
O70.1 Second degree perineal laceration during delivery
0.827 0.173 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.818 0.182 0.000
W19 Unspecified fall
0.818 0.182 0.000
G30-G32 Other degenerative diseases of the nervous system
0.817 0.183 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.815 0.185 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.815 0.185 0.000
O66 Other obstructed labour
0.814 0.186 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.814 0.186 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.813 0.187 0.000
C77.8 Lymph nodes of multiple regions
0.811 0.189 0.000
N13.3 Other and unspecified hydronephrosis
0.811 0.189 0.000
G81.9 Hemiplegia, unspecified
0.811 0.189 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.811 0.189 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.811 0.189 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.810 0.190 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.809 0.191 0.000
C25.9 Pancreas, unspecified
0.808 0.192 0.000
C21 Malignant neoplasm of anus and anal canal
0.808 0.192 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.808 0.192 0.000
C23 Malignant neoplasm of gallbladder
0.803 0.197 0.000
M40-M43 Deforming dorsopathies
0.802 0.198 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.800 0.200 0.000
S60-S69 Injuries to the wrist and hand
0.797 0.203 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.797 0.203 0.000
X60-X84 Intentional self-harm
0.796 0.204 0.000
M45 Ankylosing spondylitis
0.796 0.204 0.000
M91-M94 Chondropathies
0.795 0.205 0.000
N99-N99 Other disorders of the genitourinary system
0.794 0.206 0.000
O85-O92 Complications predominantly related to the puerperium
0.792 0.208 0.000
G90-G99 Other disorders of the nervous system
0.791 0.209 0.000
O47 False labour
0.791 0.209 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.791 0.209 0.000
B35-B49 Mycoses
0.789 0.211 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.788 0.212 0.000
O62 Abnormalities of forces of labour
0.787 0.213 0.000
N13.8 Other obstructive and reflux uropathy
0.787 0.213 0.000
M13.9 Arthritis, unspecified
0.786 0.214 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.785 0.215 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.783 0.217 0.000
Chapter V Mental and behavioural disorders
0.782 0.218 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.779 0.221 0.000
G71 Primary disorders of muscles
0.779 0.221 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.779 0.221 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.777 0.223 0.000
D00-D09 In situ neoplasms
0.777 0.223 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.777 0.223 0.000
C77.0 Lymph nodes of head, face and neck
0.777 0.223 0.000
M07 Psoriatic and enteropathic arthropathies
0.776 0.224 0.000
S42.0 Fracture of clavicle
0.776 0.224 0.000
W19.9 Unspecified place
0.775 0.225 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.775 0.225 0.000
B02 Zoster [herpes zoster]
0.774 0.226 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.773 0.226 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.772 0.228 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.771 0.229 0.000
M10.9 Gout, unspecified
0.768 0.232 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.768 0.232 0.000
S70-S79 Injuries to the hip and thigh
0.767 0.233 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.766 0.234 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.764 0.236 0.000
T79-T79 Certain early complications of trauma
0.763 0.237 0.000
O61 Failed induction of labour
0.762 0.238 0.000
N03 Chronic nephritic syndrome
0.760 0.240 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.760 0.240 0.000
S10-S19 Injuries to the neck
0.759 0.241 0.000
O75.8 Other specified complications of labour and delivery
0.758 0.242 0.000
O00 Ectopic pregnancy
0.757 0.243 0.000
B15-B19 Viral hepatitis
0.757 0.243 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.757 0.243 0.000
T40.4 Other synthetic narcotics
0.756 0.244 0.000
M86-M90 Other osteopathies
0.755 0.245 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.755 0.245 0.000
G72 Other myopathies
0.754 0.246 0.000
Y43.0 Antiallergic and antiemetic drugs
0.753 0.247 0.000
W17 Other fall from one level to another
0.753 0.247 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.749 0.251 0.000
C25.0 Head of pancreas
0.749 0.251 0.000
H54 Blindness and low vision
0.748 0.252 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.747 0.253 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.746 0.254 0.000
C79.6 Secondary malignant neoplasm of ovary
0.745 0.254 0.000
V80-V89 Other land transport accidents
0.744 0.256 0.000
N13.4 Hydroureter
0.742 0.257 0.000
S20-S29 Injuries to the thorax
0.742 0.258 0.000
Y40 Systemic antibiotics
0.741 0.259 0.000
S90 Superficial injury of ankle and foot
0.741 0.259 0.000
V10-V19 Pedal cyclist injured in transport accident
0.740 0.260 0.000
C60-C63 Malignant neoplasms of male genital organs
0.740 0.260 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.739 0.261 0.000
N25-N29 Other disorders of kidney and ureter
0.738 0.262 0.000
S42.00 Fracture of clavicle (closed)
0.738 0.262 0.000
C54 Malignant neoplasm of corpus uteri
0.738 0.262 0.000
G25 Other extrapyramidal and movement disorders
0.738 0.262 0.000
N30-N39 Other diseases of urinary system
0.737 0.263 0.000
C80 Malignant neoplasm without specification of site
0.737 0.263 0.000
N64 Other disorders of breast
0.736 0.264 0.000
W07 Fall involving chair
0.736 0.264 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.735 0.265 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
T66-T78 Other and unspecified effects of external causes
0.733 0.266 0.000
O48 Prolonged pregnancy
0.733 0.267 0.000
S40 Superficial injury of shoulder and upper arm
0.732 0.268 0.000
G80 Infantile cerebral palsy
0.732 0.268 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.732 0.268 0.000
Q80-Q89 Other congenital malformations
0.731 0.269 0.000
E00-E07 Disorders of thyroid gland
0.726 0.274 0.000
O70.0 First degree perineal laceration during delivery
0.725 0.275 0.000
M05 Seropositive rheumatoid arthritis
0.725 0.275 0.000
C78.2 Secondary malignant neoplasm of pleura
0.724 0.276 0.000
H55-H59 Other disorders of eye and adnexa
0.724 0.276 0.000
O70.2 Third degree perineal laceration during delivery
0.724 0.276 0.000
S50-S59 Injuries to the elbow and forearm
0.723 0.277 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.722 0.278 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.722 0.278 0.000
Y43.4 Immunosuppressive agents
0.721 0.279 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.721 0.279 0.000
C22.9 Liver, unspecified
0.721 0.279 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.720 0.280 0.000
Y44.2 Anticoagulants
0.719 0.281 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.719 0.281 0.000
E03 Other hypothyroidism
0.719 0.281 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C67 Malignant neoplasm of bladder
0.717 0.283 0.000
H53.1 Subjective visual disturbances
0.717 0.283 0.000
O74 Complications of anaesthesia during labour and delivery
0.716 0.284 0.000
O73 Retained placenta and membranes, without haemorrhage
0.716 0.284 0.000
O71 Other obstetric trauma
0.716 0.284 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.716 0.284 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.716 0.284 0.000
O60 Preterm delivery
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.715 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.284 0.000
E03.9 Hypothyroidism, unspecified
0.715 0.285 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.715 0.285 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.285 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X20-X29 Contact with venomous animals and plants
0.714 0.286 0.000
X10-X19 Contact with heat and hot substances
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W75-W84 Other accidental threats to breathing
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V40-V49 Car occupant injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
O41 Other disorders of amniotic fluid and membranes
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
M10.99 Gout, unspecified (Site unspecified)
0.713 0.287 0.000
B37 Candidiasis
0.712 0.288 0.000
N13.6 Pyonephrosis
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.289 0.000
H10-H13 Disorders of conjunctiva
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.709 0.291 0.000
C17 Malignant neoplasm of small intestine
0.709 0.291 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
M81 Osteoporosis without pathological fracture
0.707 0.292 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.707 0.292 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.707 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.707 0.293 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y48 Anaesthetics and therapeutic gases
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
G83 Other paralytic syndromes
0.707 0.293 0.000
O75.0 Maternal distress during labour and delivery
0.707 0.293 0.000
C15 Malignant neoplasm of oesophagus
0.707 0.293 0.000
O43 Placental disorders
0.705 0.295 0.000
W06 Fall involving bed
0.705 0.295 0.000
G82 Paraplegia and tetraplegia
0.704 0.296 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.704 0.296 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.703 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.703 0.297 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
G12 Spinal muscular atrophy and related syndromes
0.700 0.300 0.000
M47.1 Other spondylosis with myelopathy
0.700 0.300 0.000
M06.4 Inflammatory polyarthropathy
0.699 0.301 0.000
M49 Spondylopathies in diseases classified elsewhere
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.699 0.301 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.698 0.302 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.698 0.302 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.696 0.304 0.000
C09 Malignant neoplasm of tonsil
0.695 0.305 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.695 0.305 0.000
N03.9 Unspecified
0.693 0.307 0.000
M80 Osteoporosis with pathological fracture
0.692 0.308 0.000
N02 Recurrent and persistent haematuria
0.692 0.308 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.691 0.309 0.000
C53 Malignant neoplasm of cervix uteri
0.690 0.309 0.000
Q50-Q56 Congenital malformations of genital organs
0.690 0.310 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.689 0.311 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.689 0.311 0.000
N11 Chronic tubulo-interstitial nephritis
0.688 0.311 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.688 0.312 0.000
N15 Other renal tubulo-interstitial diseases
0.688 0.312 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.688 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.688 0.312 0.000
C56 Malignant neoplasm of ovary
0.688 0.312 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.687 0.313 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.686 0.314 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.685 0.314 0.000
A80-A89 Viral infections of the central nervous system
0.684 0.316 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
M84.4 Pathological fracture, not elsewhere classified
0.683 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.683 0.317 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.682 0.318 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.682 0.318 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.682 0.318 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.682 0.318 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.682 0.318 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.682 0.318 0.000
Q00-Q07 Congenital malformations of the nervous system
0.681 0.319 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.680 0.320 0.000
F20 Schizophrenia
0.680 0.320 0.000
M65-M68 Disorders of synovium and tendon
0.679 0.321 0.000
C21.1 Anal canal
0.679 0.321 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.678 0.322 0.000
B02.2 Zoster with other nervous system involvement
0.678 0.322 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.677 0.323 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.677 0.323 0.000
Y43.9 Primarily systemic agent, unspecified
0.677 0.323 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.677 0.323 0.000
Y43.6 Enzymes, not elsewhere classified
0.677 0.323 0.000
Y43.5 Acidifying and alkalising agents
0.677 0.323 0.000
Y43.2 Antineoplastic natural products
0.677 0.323 0.000
Y43.1 Antineoplastic antimetabolites
0.677 0.323 0.000
M46 Other inflammatory spondylopathies
0.677 0.323 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.676 0.324 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.676 0.324 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.676 0.324 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.676 0.324 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.676 0.324 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.676 0.324 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.676 0.324 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.676 0.324 0.000
T36 Poisoning by systemic antibiotics
0.676 0.324 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.674 0.326 0.000
Q35-Q37 Cleft lip and cleft palate
0.674 0.326 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.674 0.326 0.000
C50-C50 Malignant neoplasm of breast
0.674 0.326 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.674 0.326 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.674 0.326 0.000
Y42.5 Other oestrogens and progestogens
0.674 0.326 0.000
G70 Myasthenia gravis and other myoneural disorders
0.671 0.328 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.670 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.670 0.330 0.000
M83 Adult osteomalacia
0.670 0.330 0.000
G71.1 Myotonic disorders
0.670 0.330 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.669 0.331 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.669 0.331 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.669 0.331 0.000
B99-B99 Other infectious diseases
0.668 0.332 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.668 0.332 0.000
O47.9 False labour, unspecified
0.668 0.332 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.667 0.333 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.667 0.333 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.666 0.334 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.666 0.334 0.000
H54.9 Unspecified visual impairment (binocular)
0.666 0.334 0.000
O00.1 Tubal pregnancy
0.666 0.334 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.664 0.336 0.000
W18 Other fall on same level
0.664 0.336 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.664 0.336 0.000
W15 Fall from cliff
0.664 0.336 0.000
W14 Fall from tree
0.664 0.336 0.000
W12 Fall on and from scaffolding
0.664 0.336 0.000
W11 Fall on and from ladder
0.664 0.336 0.000
W10 Fall on and from stairs and steps
0.664 0.336 0.000
W09 Fall involving playground equipment
0.664 0.336 0.000
W08 Fall involving other furniture
0.664 0.336 0.000
W05 Fall involving wheelchair
0.664 0.336 0.000
W04 Fall while being carried or supported by other persons
0.664 0.336 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.664 0.336 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.664 0.336 0.000
W00 Fall on same level involving ice and snow
0.664 0.336 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.663 0.336 0.000
B02.9 Zoster without complication
0.664 0.336 0.000
O63 Long labour
0.663 0.337 0.000
C77.4 Inguinal and lower limb lymph nodes
0.663 0.337 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.662 0.337 0.000
O80-O84 Delivery
0.662 0.338 0.000
M43 Other deforming dorsopathies
0.662 0.338 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.662 0.338 0.000
H40-H42 Glaucoma
0.662 0.338 0.000
O70.9 Perineal laceration during delivery, unspecified
0.661 0.339 0.000
O70.3 Fourth degree perineal laceration during delivery
0.661 0.339 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.661 0.339 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.661 0.339 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.661 0.339 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.659 0.341 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.658 0.341 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.658 0.342 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.658 0.342 0.000
B18 Chronic viral hepatitis
0.658 0.342 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.657 0.343 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.656 0.344 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.655 0.345 0.000
D03 Melanoma in situ
0.653 0.346 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.653 0.347 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.653 0.347 0.000
S48 Traumatic amputation of shoulder and upper arm
0.653 0.347 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.653 0.347 0.000
S44 Injury of nerves at shoulder and upper arm level
0.653 0.347 0.000
S41 Open wound of shoulder and upper arm
0.653 0.347 0.000
S47 Crushing injury of shoulder and upper arm
0.653 0.347 0.000
O75.9 Complication of labour and delivery, unspecified
0.653 0.347 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.653 0.347 0.000
O75.4 Other complications of obstetric surgery and procedures
0.653 0.347 0.000
O75.3 Other infection during labour
0.653 0.347 0.000
O75.1 Shock during or following labour and delivery
0.653 0.347 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.652 0.348 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.650 0.350 0.000
G72.9 Myopathy, unspecified
0.650 0.350 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.650 0.350 0.000
C25.8 Overlapping lesion of pancreas
0.649 0.351 0.000
C25.7 Other parts of pancreas
0.649 0.351 0.000
C25.4 Endocrine pancreas
0.649 0.351 0.000
C25.3 Pancreatic duct
0.649 0.351 0.000
C25.2 Tail of pancreas
0.649 0.351 0.000
C25.1 Body of pancreas
0.649 0.351 0.000
T93 Sequelae of injuries of lower limb
0.649 0.351 0.000
M47.2 Other spondylosis with radiculopathy
0.648 0.352 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.647 0.352 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.647 0.353 0.000
M06.8 Other specified rheumatoid arthritis
0.646 0.354 0.000
M06.3 Rheumatoid nodule
0.646 0.354 0.000
M06.2 Rheumatoid bursitis
0.646 0.354 0.000
M06.1 Adult-onset Still's disease
0.646 0.354 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.646 0.354 0.000
O45 Premature separation of placenta [abruptio placentae]
0.644 0.356 0.000
O44 Placenta praevia
0.644 0.356 0.000
O33 Maternal care for known or suspected disproportion
0.644 0.356 0.000
O31 Complications specific to multiple gestation
0.644 0.356 0.000
O40 Polyhydramnios
0.644 0.356 0.000
M13.98 Arthritis, unspecified (Other)
0.644 0.356 0.000
D75 Other diseases of blood and blood-forming organs
0.644 0.356 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.644 0.356 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.644 0.356 0.000
O86 Other puerperal infections
0.643 0.356 0.000
C22.0 Liver cell carcinoma
0.643 0.357 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.643 0.357 0.000
M50-M54 Other dorsopathies
0.643 0.357 0.000
O62.3 Precipitate labour
0.642 0.358 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.642 0.358 0.000
B65-B83 Helminthiases
0.642 0.358 0.000
B50-B64 Protozoal diseases
0.642 0.358 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.642 0.358 0.000
A75-A79 Rickettsioses
0.642 0.358 0.000
A70-A74 Other diseases caused by chlamydiae
0.642 0.358 0.000
A65-A69 Other spirochaetal diseases
0.642 0.358 0.000
A20-A28 Certain zoonotic bacterial diseases
0.642 0.358 0.000
A15-A19 Tuberculosis
0.642 0.358 0.000
G30 Alzheimer's disease
0.642 0.358 0.000
B02.3 Zoster ocular disease
0.641 0.359 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.640 0.360 0.000
C51 Malignant neoplasm of vulva
0.640 0.360 0.000
C58 Malignant neoplasm of placenta
0.640 0.360 0.000
C52 Malignant neoplasm of vagina
0.640 0.360 0.000
M11 Other crystal arthropathies
0.639 0.361 0.000
Q76 Congenital malformations of spine and bony thorax
0.639 0.361 0.000
N73 Other female pelvic inflammatory diseases
0.638 0.362 0.000
M85 Other disorders of bone density and structure
0.637 0.362 0.000
T50.8 Diagnostic agents
0.637 0.363 0.000
T50.7 Analeptics and opioid receptor antagonists
0.637 0.363 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.637 0.363 0.000
T50.5 Appetite depressants
0.637 0.363 0.000
T50.4 Drugs affecting uric acid metabolism
0.637 0.363 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.637 0.363 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.637 0.363 0.000
T50.1 Loop [high-ceiling] diuretics
0.637 0.363 0.000
T50.0 Mineralocorticoids and their antagonists
0.637 0.363 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.637 0.363 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.637 0.363 0.000
Y52.7 Peripheral vasodilators
0.637 0.363 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.637 0.363 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.637 0.363 0.000
Y52.1 Calcium-channel blockers
0.637 0.363 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.637 0.363 0.000
C45 Mesothelioma
0.637 0.363 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.636 0.364 0.000
N60 Benign mammary dysplasia
0.635 0.365 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.635 0.365 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.635 0.365 0.000
M93 Other osteochondropathies
0.635 0.365 0.000
T20 Burn and corrosion of head and neck
0.634 0.365 0.000
F60-F69 Disorders of adult personality and behaviour
0.634 0.366 0.000
H18 Other disorders of cornea
0.633 0.367 0.000
H53.9 Visual disturbance, unspecified
0.633 0.367 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.632 0.368 0.000
D45 Polycythaemia vera
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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