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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4279480
log Bayes Factor = 196.624
Chromosome 6   position 32,290,927  (GRCh37) Explore rs4279480 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
J33 Nasal polyp
0.000 0.003 0.997
J33.0 Polyp of nasal cavity
0.000 0.003 0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.003 0.997
K90 Intestinal malabsorption
0.000 0.003 0.997
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
K90-K93 Other diseases of the digestive system
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.995 0.005 0.000
E11.1 With ketoacidosis
0.000 0.006 0.994
G37 Other demyelinating diseases of central nervous system
0.994 0.006 0.000
D64.9 Anaemia, unspecified
0.000 0.006 0.994
K70-K77 Diseases of liver
0.000 0.006 0.994
D60-D64 Aplastic and other anaemias
0.000 0.006 0.994
D64 Other anaemias
0.000 0.007 0.993
E11.3 With ophthalmic complications
0.000 0.007 0.993
G37.9 Demyelinating disease of central nervous system, unspecified
0.993 0.007 0.000
E10.5 With peripheral circulatory complications
0.000 0.008 0.992
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.008 0.992
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.009 0.991
J33.8 Other polyp of sinus
0.000 0.009 0.991
J33.9 Nasal polyp, unspecified
0.000 0.010 0.990
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.010 0.990
D50-D53 Nutritional anaemias
0.000 0.011 0.989
L40-L45 Papulosquamous disorders
0.000 0.012 0.988
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.014 0.986
E06 Thyroiditis
0.000 0.014 0.986
K75 Other inflammatory liver diseases
0.000 0.014 0.986
D50 Iron deficiency anaemia
0.000 0.014 0.986
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.018 0.982
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.019 0.981
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.020 0.980
D50.9 Iron deficiency anaemia, unspecified
0.000 0.021 0.979
E10.2 With renal complications
0.000 0.023 0.977
E06.3 Autoimmune thyroiditis
0.000 0.023 0.977
K75.4 Autoimmune hepatitis
0.000 0.024 0.976
E70-E90 Metabolic disorders
0.000 0.029 0.971
H43-H45 Disorders of vitreous body and globe
0.000 0.031 0.969
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.034 0.966
K74 Fibrosis and cirrhosis of liver
0.000 0.035 0.965
E10.0 With coma
0.000 0.038 0.962
E07 Other disorders of thyroid
0.000 0.039 0.961
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.041 0.959
H43 Disorders of vitreous body
0.000 0.046 0.954
E83 Disorders of mineral metabolism
0.935 0.046 0.018
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.047 0.953
K50-K52 Noninfective enteritis and colitis
0.000 0.049 0.951
H34 Retinal vascular occlusions
0.000 0.053 0.947
K50 Crohn's disease [regional enteritis]
0.000 0.054 0.946
K83 Other diseases of biliary tract
0.000 0.057 0.943
E88 Other metabolic disorders
0.000 0.058 0.942
E11.2 With renal complications
0.000 0.058 0.942
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.058 0.942
H33 Retinal detachments and breaks
0.000 0.059 0.941
L40.0 Psoriasis vulgaris
0.000 0.060 0.940
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.068 0.932
H33.3 Retinal breaks without detachment
0.000 0.070 0.930
D50.8 Other iron deficiency anaemias
0.000 0.071 0.929
K74.3 Primary biliary cirrhosis
0.000 0.071 0.929
K83.1 Obstruction of bile duct
0.000 0.072 0.928
K81 Cholecystitis
0.000 0.074 0.926
K50.1 Crohn's disease of large intestine
0.000 0.080 0.920
E07.9 Disorder of thyroid, unspecified
0.000 0.082 0.918
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.083 0.917
H43.3 Other vitreous opacities
0.000 0.085 0.915
K81.9 Cholecystitis, unspecified
0.000 0.086 0.914
M06.4 Inflammatory polyarthropathy
0.000 0.086 0.914
M06.3 Rheumatoid nodule
0.000 0.088 0.912
M35.3 Polymyalgia rheumatica
0.000 0.091 0.909
E10.8 With unspecified complications
0.000 0.091 0.909
G37.8 Other specified demyelinating diseases of central nervous system
0.902 0.098 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.100 0.900
M35 Other systemic involvement of connective tissue
0.000 0.103 0.897
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.103 0.897
E83.3 Disorders of phosphorus metabolism
0.893 0.104 0.003
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.105 0.895
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.105 0.895
K75.8 Other specified inflammatory liver diseases
0.000 0.107 0.893
K73 Chronic hepatitis, not elsewhere classified
0.000 0.110 0.890
M20-M25 Other joint disorders
0.000 0.110 0.890
L40.8 Other psoriasis
0.000 0.120 0.880
E78.0 Pure hypercholesterolaemia
0.000 0.125 0.875
K83.0 Cholangitis
0.000 0.126 0.874
H35 Other retinal disorders
0.000 0.127 0.873
E78.2 Mixed hyperlipidaemia
0.000 0.128 0.872
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.132 0.868
M91-M94 Chondropathies
0.000 0.140 0.860
L40.1 Generalised pustular psoriasis
0.000 0.143 0.857
K74.5 Biliary cirrhosis, unspecified
0.000 0.148 0.852
H53-H54 Visual disturbances and blindness
0.000 0.149 0.851
L80 Vitiligo
0.000 0.152 0.848
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.156 0.844
E86 Volume depletion
0.000 0.157 0.843
E10.6 With other specified complications
0.000 0.159 0.841
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.162 0.838
E78.6 Lipoprotein deficiency
0.000 0.163 0.837
K50.0 Crohn's disease of small intestine
0.000 0.163 0.837
E14.1 With ketoacidosis
0.000 0.166 0.834
E83.5 Disorders of calcium metabolism
0.833 0.167 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.169 0.831
H35.8 Other specified retinal disorders
0.000 0.169 0.831
E14.6 With other specified complications
0.000 0.171 0.829
E03.8 Other specified hypothyroidism
0.000 0.173 0.827
H33.4 Traction detachment of retina
0.000 0.178 0.822
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.179 0.821
H20 Iridocyclitis
0.000 0.182 0.818
H34.2 Other retinal artery occlusions
0.000 0.184 0.816
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.184 0.816
H43.1 Vitreous haemorrhage
0.000 0.192 0.808
H34.8 Other retinal vascular occlusions
0.000 0.196 0.804
H35.4 Peripheral retinal degeneration
0.000 0.199 0.801
E14.8 With unspecified complications
0.000 0.199 0.801
M94 Other disorders of cartilage
0.000 0.200 0.800
E11.8 With unspecified complications
0.000 0.202 0.798
H54 Blindness and low vision
0.000 0.206 0.794
E11.4 With neurological complications
0.000 0.206 0.794
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.207 0.793
E83.9 Disorder of mineral metabolism, unspecified
0.779 0.210 0.010
K50.8 Other Crohn's disease
0.000 0.214 0.786
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.215 0.785
K81.1 Chronic cholecystitis
0.000 0.215 0.785
E07.8 Other specified disorders of thyroid
0.000 0.219 0.781
H20.0 Acute and subacute iridocyclitis
0.000 0.222 0.778
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.223 0.777
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.225 0.775
H34.9 Retinal vascular occlusion, unspecified
0.000 0.226 0.774
M86-M90 Other osteopathies
0.000 0.226 0.774
H43.9 Disorder of vitreous body, unspecified
0.000 0.227 0.773
L40.3 Pustulosis palmaris et plantaris
0.000 0.228 0.772
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.229 0.771
H43.2 Crystalline deposits in vitreous body
0.000 0.230 0.770
J33.1 Polypoid sinus degeneration
0.000 0.232 0.768
L10-L14 Bullous disorders
0.000 0.232 0.768
E88.2 Lipomatosis, not elsewhere classified
0.000 0.233 0.767
H46 Optic neuritis
0.000 0.233 0.767
M35.1 Other overlap syndromes
0.000 0.234 0.766
H35.2 Other proliferative retinopathy
0.000 0.234 0.766
K50.9 Crohn's disease, unspecified
0.000 0.235 0.765
E78.4 Other hyperlipidaemia
0.000 0.235 0.765
E74 Other disorders of carbohydrate metabolism
0.000 0.236 0.764
M06.34 Rheumatoid nodule (Hand)
0.000 0.238 0.762
E14.4 With neurological complications
0.000 0.241 0.759
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.241 0.759
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.242 0.758
M34 Systemic sclerosis
0.000 0.243 0.757
E14.2 Withrenal complications
0.000 0.245 0.755
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.246 0.754
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.247 0.753
H54.7 Unspecified visual loss
0.000 0.249 0.751
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.252 0.748
E16.1 Other hypoglycaemia
0.000 0.256 0.744
D53 Other nutritional anaemias
0.000 0.257 0.743
M94.8 Other specified disorders of cartilage
0.000 0.258 0.742
D62 Acute posthaemorrhagic anaemia
0.000 0.258 0.742
L40.4 Guttate psoriasis
0.000 0.260 0.740
E78.1 Pure hyperglyceridaemia
0.000 0.260 0.740
M12 Other specific arthropathies
0.000 0.266 0.734
E88.8 Other specified metabolic disorders
0.000 0.266 0.734
E11.5 With peripheral circulatory complications
0.000 0.267 0.733
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.268 0.732
M86 Osteomyelitis
0.000 0.268 0.732
H20.9 Iridocyclitis, unspecified
0.000 0.268 0.732
K90.9 Intestinal malabsorption, unspecified
0.000 0.273 0.727
M05.2 Rheumatoid vasculitis
0.000 0.275 0.725
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.277 0.723
K71 Toxic liver disease
0.000 0.279 0.721
M35.7 Hypermobility syndrome
0.000 0.279 0.721
H34.1 Central retinal artery occlusion
0.000 0.280 0.720
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.280 0.720
E78.8 Other disorders of lipoprotein metabolism
0.000 0.281 0.719
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.715
M07.2 Psoriatic spondylitis
0.000 0.284 0.715
M07.1 Arthritis mutilans
0.000 0.284 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.715
K90.3 Pancreatic steatorrhoea
0.000 0.285 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.285 0.715
K90.1 Tropical sprue
0.000 0.285 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.715
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.715
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.715
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.287 0.713
K77 Liver disorders in diseases classified elsewhere
0.000 0.287 0.712
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.288 0.712
D64.4 Congenital dyserythropoietic anaemia
0.000 0.288 0.712
D64.3 Other sideroblastic anaemias
0.000 0.288 0.712
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.288 0.712
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.288 0.712
D64.0 Hereditary sideroblastic anaemia
0.000 0.288 0.712
G36 Other acute disseminated demyelination
0.712 0.288 0.000
K86 Other diseases of pancreas
0.000 0.289 0.711
L44 Other papulosquamous disorders
0.000 0.291 0.709
L41 Parapsoriasis
0.000 0.291 0.709
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.291 0.709
E06.5 Other chronic thyroiditis
0.000 0.293 0.707
E06.4 Drug-induced thyroiditis
0.000 0.293 0.707
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.293 0.707
E06.1 Subacute thyroiditis
0.000 0.293 0.707
E06.0 Acute thyroiditis
0.000 0.293 0.707
K75.2 Nonspecific reactive hepatitis
0.000 0.293 0.707
K75.1 Phlebitis of portal vein
0.000 0.293 0.707
M07.6 Other enteropathic arthropathies
0.000 0.295 0.705
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.296 0.703
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.297 0.702
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.298 0.702
D50.1 Sideropenic dysphagia
0.000 0.298 0.701
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.301 0.699
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.301 0.699
E70 Disorders of aromatic amino-acid metabolism
0.000 0.301 0.698
M86.9 Osteomyelitis, unspecified
0.000 0.302 0.698
E77 Disorders of glycoprotein metabolism
0.000 0.304 0.696
E76 Disorders of glycosaminoglycan metabolism
0.000 0.304 0.696
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.304 0.696
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.304 0.696
E06.9 Thyroiditis, unspecified
0.000 0.305 0.695
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.305 0.695
L84 Corns and callosities
0.000 0.306 0.694
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.307 0.693
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.308 0.692
K74.4 Secondary biliary cirrhosis
0.000 0.308 0.692
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.308 0.692
E13 Other specified diabetes mellitus
0.000 0.310 0.689
H35.7 Separation of retinal layers
0.000 0.311 0.689
E07.1 Dyshormogenetic goitre
0.000 0.311 0.689
E07.0 Hypersecretion of calcitonin
0.000 0.311 0.689
H54.0 Blindness, both eyes
0.000 0.313 0.687
K72 Hepatic failure, not elsewhere classified
0.000 0.315 0.685
E83.8 Other disorders of mineral metabolism
0.671 0.316 0.013
E83.2 Disorders of zinc metabolism
0.671 0.316 0.013
E83.0 Disorders of copper metabolism
0.671 0.316 0.013
E78.3 Hyperchylomicronaemia
0.000 0.316 0.684
H43.8 Other disorders of vitreous body
0.000 0.317 0.683
E88.3 Tumour lysis syndrome
0.000 0.317 0.683
H30 Chorioretinal inflammation
0.000 0.321 0.679
H34.0 Transient retinal artery occlusion
0.000 0.321 0.679
K73.9 Chronic hepatitis, unspecified
0.000 0.321 0.679
H33.1 Retinoschisis and retinal cysts
0.000 0.322 0.678
M06.8 Other specified rheumatoid arthritis
0.000 0.322 0.678
K83.4 Spasm of sphincter of Oddi
0.000 0.322 0.678
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.323 0.677
K83.5 Biliary cyst
0.000 0.324 0.676
K83.2 Perforation of bile duct
0.000 0.324 0.676
E14.5 With peripheral circulatory complications
0.000 0.324 0.676
E88.9 Metabolic disorder, unspecified
0.000 0.324 0.675
E85 Amyloidosis
0.000 0.326 0.674
M35.2 Behcet's disease
0.000 0.328 0.672
M60-M63 Disorders of muscles
0.000 0.328 0.671
M34.1 CR(E)ST syndrome
0.000 0.329 0.671
E40-E46 Malnutrition
0.000 0.330 0.669
H43.0 Vitreous prolapse
0.000 0.333 0.667
H47.2 Optic atrophy
0.000 0.339 0.661
M94.88 Other specified disorders of cartilage (Other)
0.000 0.339 0.661
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.340 0.660
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.341 0.659
I10 Essential (primary) hypertension
0.000 0.344 0.656
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.344 0.655
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.344 0.655
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.344 0.655
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.344 0.655
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.344 0.655
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.344 0.655
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.344 0.655
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.344 0.655
M14 Arthropathies in other diseases classified elsewhere
0.000 0.345 0.654
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.346 0.654
M06.38 Rheumatoid nodule (Other)
0.000 0.346 0.654
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.346 0.654
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.346 0.654
M06.33 Rheumatoid nodule (Forearm)
0.000 0.346 0.654
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.346 0.654
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.346 0.654
H15 Disorders of sclera
0.000 0.346 0.654
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.351 0.649
E89.0 Postprocedural hypothyroidism
0.000 0.353 0.647
E11.6 With other specified complications
0.000 0.354 0.646
M94.86 Other specified disorders of cartilage (Lower leg)
0.000 0.354 0.646
H20.1 Chronic iridocyclitis
0.000 0.355 0.645
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.355 0.645
L87 Transepidermal elimination disorders
0.000 0.355 0.645
L86 Keratoderma in diseases classified elsewhere
0.000 0.355 0.645
H54.2 Low vision, both eyes
0.000 0.355 0.645
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.357 0.643
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.357 0.643
M35.5 Multifocal fibrosclerosis
0.000 0.357 0.643
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.357 0.643
E79 Disorders of purine and pyrimidine metabolism
0.000 0.357 0.643
M23 Internal derangement of knee
0.000 0.357 0.643
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.358 0.642
L83 Acanthosis nigricans
0.000 0.358 0.642
L85 Other epidermal thickening
0.000 0.360 0.640
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.360 0.639
M23.3 Other meniscus derangements
0.000 0.362 0.638
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.362 0.638
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.362 0.638
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.362 0.638
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.364 0.636
L95.8 Other vasculitis limited to skin
0.000 0.364 0.636
E72 Other disorders of amino-acid metabolism
0.000 0.365 0.635
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.366 0.634
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.630 0.370 0.000
L92.0 Granuloma annulare
0.000 0.370 0.629
L13 Other bullous disorders
0.000 0.372 0.628
H35.1 Retinopathy of prematurity
0.000 0.374 0.626
M00-M03 Infectious arthropathies
0.000 0.375 0.625
L94 Other localised connective tissue disorders
0.000 0.376 0.624
L90 Atrophic disorders of skin
0.000 0.377 0.623
M91 Juvenile osteochondrosis of hip and pelvis
0.000 0.381 0.619
E05.8 Other thyrotoxicosis
0.000 0.381 0.619
H35.6 Retinal haemorrhage
0.000 0.381 0.619
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.384 0.616
I10-I15 Hypertensive diseases
0.000 0.385 0.615
E73 Lactose intolerance
0.000 0.386 0.614
M94.2 Chondromalacia
0.000 0.387 0.613
D80-D89 Certain disorders involving the immune mechanism
0.000 0.388 0.612
E84 Cystic fibrosis
0.001 0.389 0.610
K75.9 Inflammatory liver disease, unspecified
0.000 0.390 0.610
H54.1 Blindness, one eye, low vision, other eye
0.000 0.391 0.609
E03.1 Congenital hypothyroidism without goitre
0.000 0.393 0.607
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.394 0.605
M33 Dermatopolymyositis
0.000 0.396 0.604
M10 Gout
0.000 0.399 0.601
K83.3 Fistula of bile duct
0.000 0.401 0.599
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.401 0.598
L85.8 Other specified epidermal thickening
0.000 0.403 0.597
E11.0 With coma
0.000 0.404 0.596
M94.9 Disorder of cartilage, unspecified
0.000 0.404 0.596
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.406 0.594
L93 Lupus erythematosus
0.000 0.407 0.593
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.000 0.410 0.590
M86.6 Other chronic osteomyelitis
0.000 0.410 0.590
H20.2 Lens-induced iridocyclitis
0.000 0.413 0.586
K82 Other diseases of gallbladder
0.000 0.414 0.586
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.416 0.584
M93 Other osteochondropathies
0.000 0.422 0.578
M12.3 Palindromic rheumatism
0.000 0.422 0.578
E65-E68 Obesity and other hyperalimentation
0.000 0.422 0.578
K81.8 Other cholecystitis
0.000 0.425 0.575
M94.3 Chondrolysis
0.000 0.426 0.574
M94.1 Relapsing polychondritis
0.000 0.426 0.574
M94.0 Chondrocostal junction syndrome [Tietze]
0.000 0.426 0.574
M45-M49 Spondylopathies
0.000 0.428 0.572
H54.3 Unqualified visual loss, both eyes
0.000 0.430 0.570
I12 Hypertensive renal disease
0.000 0.430 0.570
K74.1 Hepatic sclerosis
0.000 0.432 0.568
M65-M68 Disorders of synovium and tendon
0.000 0.432 0.568
Chapter VIII Diseases of the ear and mastoid process
0.000 0.433 0.567
M23.30 Other meniscus derangements (Multiple sites)
0.000 0.433 0.567
D53.9 Nutritional anaemia, unspecified
0.000 0.433 0.566
H54.5 Low vision, one eye
0.000 0.434 0.566
M32 Systemic lupus erythematosus
0.000 0.435 0.565
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.437 0.563
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.437 0.563
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.000 0.439 0.561
I12.9 Hypertensive renal disease without renal failure
0.000 0.439 0.561
L12 Pemphigoid
0.000 0.440 0.560
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.000 0.441 0.559
M34.9 Systemic sclerosis, unspecified
0.000 0.441 0.559
H54.6 Unqualified visual loss, one eye
0.000 0.442 0.558
M88 Paget's disease of bone [osteitis deformans]
0.000 0.442 0.558
H44 Disorders of globe
0.000 0.445 0.555
K86.3 Pseudocyst of pancreas
0.000 0.446 0.554
H47.3 Other disorders of optic disk
0.000 0.446 0.554
L90.0 Lichen sclerosus et atrophicus
0.000 0.446 0.554
L10 Pemphigus
0.000 0.449 0.551
L14 Bullous disorders in diseases classified elsewhere
0.000 0.449 0.551
D64.8 Other specified anaemias
0.000 0.450 0.550
M45 Ankylosing spondylitis
0.000 0.451 0.549
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.452 0.548
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.452 0.548
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.452 0.548
E74.2 Disorders of galactose metabolism
0.000 0.452 0.548
E74.1 Disorders of fructose metabolism
0.000 0.452 0.548
E74.0 Glycogen storage disease
0.000 0.452 0.548
E85.9 Amyloidosis, unspecified
0.000 0.452 0.548
K83.9 Disease of biliary tract, unspecified
0.000 0.454 0.546
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.456 0.544
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.457 0.543
M31 Other necrotising vasculopathies
0.000 0.458 0.542
M11 Other crystal arthropathies
0.000 0.461 0.539
H35.5 Hereditary retinal dystrophy
0.000 0.462 0.538
K72.9 Hepatic failure, unspecified
0.000 0.462 0.538
H15.8 Other disorders of sclera
0.000 0.462 0.538
H47.1 Papilloedema, unspecified
0.000 0.463 0.537
M86.1 Other acute osteomyelitis
0.000 0.463 0.537
H47.7 Disorder of visual pathways, unspecified
0.000 0.464 0.536
H47.6 Disorders of visual cortex
0.000 0.464 0.536
H47.5 Disorders of other visual pathways
0.000 0.464 0.536
H47.4 Disorders of optic chiasm
0.000 0.464 0.536
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.000 0.464 0.536
M06.0 Seronegative rheumatoid arthritis
0.000 0.464 0.535
H16 Keratitis
0.000 0.466 0.534
D53.8 Other specified nutritional anaemias
0.000 0.467 0.533
D53.2 Scorbutic anaemia
0.000 0.467 0.533
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.467 0.533
D53.0 Protein deficiency anaemia
0.000 0.467 0.533
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.467 0.533
M94.84 Other specified disorders of cartilage (Hand)
0.000 0.468 0.532
M94.83 Other specified disorders of cartilage (Forearm)
0.000 0.468 0.532
M94.82 Other specified disorders of cartilage (Upper arm)
0.000 0.468 0.532
M94.80 Other specified disorders of cartilage (Multiple sites)
0.000 0.468 0.532
L88 Pyoderma gangrenosum
0.000 0.468 0.532
M35.8 Other specified systemic involvement of connective tissue
0.000 0.468 0.532
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.469 0.531
D61 Other aplastic anaemias
0.000 0.471 0.529
M34.0 Progressive systemic sclerosis
0.000 0.471 0.528
M92 Other juvenile osteochondrosis
0.000 0.472 0.528
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.472 0.528
L13.0 Dermatitis herpetiformis
0.000 0.472 0.528
D86 Sarcoidosis
0.000 0.473 0.527
M12.4 Intermittent hydrarthrosis
0.000 0.473 0.527
M12.1 Kaschin-Beck disease
0.000 0.473 0.527
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.473 0.527
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.474 0.526
K75.0 Abscess of liver
0.000 0.474 0.526
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.475 0.525
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.475 0.525

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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