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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0212
log Bayes Factor = 300.777
contains 10 variants:
rs78227251
lBF = 17.496
Chr 2 : 88,977,848
rs28925904
lBF = 27.422
Chr 4 : 144,359,490
rs78428368
lBF = 24.441
Chr 4 : 164,617,481
rs11746865
lBF = 27.995
Chr 5 : 136,600,241
rs75015237
lBF = 14.838
Chr 7 : 133,648,442
rs2106212
lBF = 24.403
Chr 8 : 12,569,241
rs79858930
lBF = 31.619
Chr10 : 83,047,434
rs117703456
lBF = 19.134
Chr13 : 43,083,754
rs117206795
lBF = 31.201
Chr15 : 67,270,650
rs181028361
lBF = 21.808
Chr18 : 9,792,830
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
1.000 0.000 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
1.000 0.000 0.000
Z86.7 Personal history of diseases of the circulatory system
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
Z86 Personal history of certain other diseases
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z70-Z76 Persons encountering health services in other circumstances
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
M79.6 Pain in limb
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
M51 Other intervertebral disk disorders
1.000 0.000 0.000
Z91 Personal history of risk-factors, not elsewhere classified
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
M54.9 Dorsalgia, unspecified
1.000 0.000 0.000
K26 Duodenal ulcer
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
K35-K38 Diseases of appendix
1.000 0.000 0.000
R51 Headache
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
Z72 Problems related to lifestyle
1.000 0.000 0.000
I95-I99 Other and unspecified disorders of the circulatory system
1.000 0.000 0.000
N10-N16 Renal tubulo-interstitial diseases
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
M23 Internal derangement of knee
1.000 0.000 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
Z90 Acquired absence of organs, not elsewhere classified
1.000 0.000 0.000
I80 Phlebitis and thrombophlebitis
1.000 0.000 0.000
M47 Spondylosis
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
O36 Maternal care for other known or suspected foetal problems
1.000 0.000 0.000
M79.8 Other specified soft tissue disorders
1.000 0.000 0.000
S80-S89 Injuries to the knee and lower leg
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.999 0.001 0.000
I95 Hypotension
0.999 0.001 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.999 0.001 0.000
Z72.0 Tobacco use
0.999 0.001 0.000
R52 Pain, not elsewhere classified
0.999 0.001 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
F31 Bipolar affective disorder
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.999 0.001 0.000
K35 Acute appendicitis
0.999 0.001 0.000
J30-J39 Other diseases of upper respiratory tract
0.999 0.001 0.000
Y95 Nosocomial condition
0.999 0.001 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.999 0.001 0.000
K86 Other diseases of pancreas
0.999 0.001 0.000
F32 Depressive episode
0.999 0.001 0.000
M54.56 Low back pain (Lumbar region)
0.999 0.001 0.000
Z97 Presence of other devices
0.998 0.002 0.000
N00-N08 Glomerular diseases
0.998 0.002 0.000
S20-S29 Injuries to the thorax
0.998 0.002 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.998 0.002 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.998 0.002 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.998 0.002 0.000
K35.9 Acute appendicitis, unspecified
0.998 0.002 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.998 0.002 0.000
K83 Other diseases of biliary tract
0.998 0.002 0.000
I67 Other cerebrovascular diseases
0.998 0.002 0.000
N18.9 Chronic renal failure, unspecified
0.998 0.002 0.000
M54.59 Low back pain (Site unspecified)
0.998 0.002 0.000
O72 Postpartum haemorrhage
0.998 0.002 0.000
I95.1 Orthostatic hypotension
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
I34 Nonrheumatic mitral valve disorders
0.997 0.003 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.997 0.003 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.997 0.003 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.997 0.003 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.997 0.003 0.000
E87.5 Hyperkalaemia
0.997 0.003 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.997 0.003 0.000
K40-K46 Hernia
0.996 0.004 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.996 0.004 0.000
F17.1 Harmful use
0.996 0.004 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.996 0.004 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.996 0.004 0.000
E78.0 Pure hypercholesterolaemia
0.996 0.004 0.000
I50 Heart failure
0.996 0.004 0.000
M25.8 Other specified joint disorders
0.995 0.005 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.995 0.005 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.995 0.005 0.000
M51.2 Other specified intervertebral disk displacement
0.995 0.005 0.000
K92 Other diseases of digestive system
0.995 0.005 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.995 0.005 0.000
J32 Chronic sinusitis
0.995 0.005 0.000
H65-H75 Diseases of middle ear and mastoid
0.995 0.005 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.995 0.005 0.000
E04 Other non-toxic goitre
0.995 0.005 0.000
J43 Emphysema
0.995 0.005 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.994 0.006 0.000
Z80 Family history of malignant neoplasm
0.994 0.006 0.000
K92.1 Melaena
0.994 0.006 0.000
M13 Other arthritis
0.994 0.006 0.000
H50 Other strabismus
0.993 0.007 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.993 0.007 0.000
M47.9 Spondylosis, unspecified
0.993 0.007 0.000
R52.1 Chronic intractable pain
0.993 0.007 0.000
M48 Other spondylopathies
0.993 0.007 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.993 0.007 0.000
I44 Atrioventricular and left bundle-branch block
0.993 0.007 0.000
J95-J99 Other diseases of the respiratory system
0.993 0.007 0.000
F31.9 Bipolar affective disorder, unspecified
0.993 0.007 0.000
G95 Other diseases of spinal cord
0.993 0.007 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.993 0.007 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.993 0.007 0.000
Z29 Need for other prophylactic measures
0.993 0.007 0.000
H60-H62 Diseases of external ear
0.992 0.008 0.000
H02 Other disorders of eyelid
0.992 0.008 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.992 0.008 0.000
O36.8 Maternal care for other specified foetal problems
0.992 0.008 0.000
Z90.5 Acquired absence of kidney
0.992 0.008 0.000
Z36 Antenatal screening
0.991 0.009 0.000
J43.9 Emphysema, unspecified
0.991 0.009 0.000
I67.8 Other specified cerebrovascular diseases
0.991 0.009 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.990 0.010 0.000
I34.0 Mitral (valve) insufficiency
0.990 0.010 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.990 0.010 0.000
C64-C68 Malignant neoplasms of urinary tract
0.990 0.010 0.000
M13.9 Arthritis, unspecified
0.990 0.010 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.990 0.010 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
N25-N29 Other disorders of kidney and ureter
0.989 0.011 0.000
E27 Other disorders of adrenal gland
0.989 0.011 0.000
O63 Long labour
0.989 0.011 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.989 0.011 0.000
R06 Abnormalities of breathing
0.988 0.012 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.988 0.012 0.000
J32.9 Chronic sinusitis, unspecified
0.988 0.012 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.988 0.012 0.000
I44.0 Atrioventricular block, first degree
0.988 0.012 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.988 0.012 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.988 0.012 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
I60 Subarachnoid haemorrhage
0.987 0.013 0.000
N13 Obstructive and reflux uropathy
0.987 0.013 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.986 0.014 0.000
M79.60 Pain in limb (Multiple sites)
0.986 0.014 0.000
Z88.6 Personal history of allergy to analgesic agent
0.986 0.014 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
K29 Gastritis and duodenitis
0.986 0.014 0.000
G30-G32 Other degenerative diseases of the nervous system
0.986 0.014 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.986 0.014 0.000
M48.0 Spinal stenosis
0.985 0.015 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.985 0.015 0.000
H02.9 Disorder of eyelid, unspecified
0.985 0.015 0.000
R79 Other abnormal findings of blood chemistry
0.985 0.015 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.984 0.016 0.000
M40-M43 Deforming dorsopathies
0.984 0.016 0.000
J98 Other respiratory disorders
0.983 0.017 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.983 0.017 0.000
E16 Other disorders of pancreatic internal secretion
0.983 0.017 0.000
H90-H95 Other disorders of ear
0.982 0.018 0.000
H55-H59 Other disorders of eye and adnexa
0.982 0.018 0.000
I63 Cerebral infarction
0.982 0.018 0.000
I49 Other cardiac arrhythmias
0.982 0.018 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.982 0.018 0.000
K85 Acute pancreatitis
0.981 0.019 0.000
M86-M90 Other osteopathies
0.981 0.019 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.980 0.020 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.980 0.020 0.000
S90-S99 Injuries to the ankle and foot
0.980 0.020 0.000
K43 Ventral hernia
0.979 0.021 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.979 0.021 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.979 0.021 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.979 0.021 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.979 0.021 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.978 0.022 0.000
R56 Convulsions, not elsewhere classified
0.978 0.022 0.000
G95.2 Cord compression, unspecified
0.978 0.022 0.000
S62 Fracture at wrist and hand level
0.978 0.022 0.000
E16.2 Hypoglycaemia, unspecified
0.978 0.022 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.977 0.023 0.000
E05.9 Thyrotoxicosis, unspecified
0.977 0.023 0.000
C67 Malignant neoplasm of bladder
0.977 0.023 0.000
E28 Ovarian dysfunction
0.977 0.023 0.000
C50-C50 Malignant neoplasm of breast
0.977 0.023 0.000
S06 Intracranial injury
0.977 0.023 0.000
L20-L30 Dermatitis and eczema
0.977 0.023 0.000
Z72.1 Alcohol use
0.977 0.023 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.976 0.024 0.000
I50.0 Congestive heart failure
0.976 0.024 0.000
K26.4 Chronic or unspecified with haemorrhage
0.976 0.024 0.000
K83.8 Other specified diseases of biliary tract
0.976 0.024 0.000
H61 Other disorders of external ear
0.976 0.024 0.000
Z73 Problems related to life-management difficulty
0.976 0.024 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.976 0.024 0.000
Z33 Pregnant state, incidental
0.975 0.025 0.000
R09.1 Pleurisy
0.975 0.025 0.000
D68 Other coagulation defects
0.975 0.025 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.975 0.025 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.974 0.026 0.000
K50-K52 Noninfective enteritis and colitis
0.974 0.026 0.000
L81 Other disorders of pigmentation
0.974 0.026 0.000
M79.66 Pain in limb (Lower leg)
0.973 0.027 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.973 0.027 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.973 0.027 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.972 0.028 0.000
M47.8 Other spondylosis
0.972 0.028 0.000
H50.1 Divergent concomitant strabismus
0.972 0.028 0.000
S81 Open wound of lower leg
0.972 0.028 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.972 0.028 0.000
Z29.2 Other prophylactic chemotherapy
0.972 0.028 0.000
L89 Decubitus ulcer
0.971 0.029 0.000
Z90.8 Acquired absence of other organs
0.971 0.029 0.000
M70.6 Trochanteric bursitis
0.971 0.029 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.971 0.029 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.971 0.029 0.000
Z88.5 Personal history of allergy to narcotic agent
0.970 0.030 0.000
Z94 Transplanted organ and tissue status
0.970 0.030 0.000
Z97.8 Presence of other specified devices
0.970 0.030 0.000
K70-K77 Diseases of liver
0.970 0.030 0.000
M84 Disorders of continuity of bone
0.970 0.030 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.970 0.030 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.969 0.031 0.000
O72.0 Third-stage haemorrhage
0.969 0.031 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.969 0.031 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.968 0.032 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.968 0.032 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.968 0.032 0.000
H02.1 Ectropion of eyelid
0.968 0.032 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.967 0.033 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.967 0.033 0.000
O72.1 Other immediate postpartum haemorrhage
0.967 0.033 0.000
M79.62 Pain in limb (Upper arm)
0.966 0.034 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.966 0.034 0.000
M51.8 Other specified intervertebral disk disorders
0.966 0.034 0.000
Chapter XXII Codes for special purposes
0.965 0.035 0.000
M41 Scoliosis
0.965 0.035 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.965 0.035 0.000
O63.9 Long labour, unspecified
0.964 0.036 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.964 0.036 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.964 0.036 0.000
R79.0 Abnormal level of blood mineral
0.964 0.036 0.000
Y45.0 Opioids and related analgesics
0.964 0.036 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.963 0.037 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.963 0.037 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.962 0.038 0.000
H61.2 Impacted cerumen
0.962 0.038 0.000
R56.8 Other and unspecified convulsions
0.962 0.038 0.000
E28.2 Polycystic ovarian syndrome
0.961 0.039 0.000
L50-L54 Urticaria and erythema
0.961 0.039 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.961 0.039 0.000
O32.1 Maternal care for breech presentation
0.961 0.039 0.000
Y45.1 Salicylates
0.961 0.039 0.000
M48.02 Spinal stenosis (Cervical region)
0.961 0.039 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.960 0.040 0.000
C50 Malignant neoplasm of breast
0.960 0.040 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.960 0.040 0.000
M06 Other rheumatoid arthritis
0.960 0.040 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.960 0.040 0.000
R63 Symptoms and signs concerning food and fluid intake
0.960 0.040 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.959 0.041 0.000
S89 Other and unspecified injuries of lower leg
0.959 0.041 0.000
A00-A09 Intestinal infectious diseases
0.959 0.041 0.000
M34 Systemic sclerosis
0.959 0.041 0.000
C67.2 Lateral wall of bladder
0.959 0.041 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.959 0.041 0.000
M54.4 Lumbago with sciatica
0.959 0.041 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.958 0.042 0.000
N13.8 Other obstructive and reflux uropathy
0.958 0.042 0.000
M23.5 Chronic instability of knee
0.958 0.042 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.957 0.043 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.957 0.043 0.000
I50.1 Left ventricular failure
0.957 0.043 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.956 0.044 0.000
L60-L75 Disorders of skin appendages
0.956 0.044 0.000
L29 Pruritus
0.955 0.045 0.000
Z71.9 Counselling, unspecified
0.955 0.045 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.955 0.045 0.000
L89.1 Stage II decubitus ulcer
0.955 0.045 0.000
N18.4 Chronic kidney disease, stage 4
0.954 0.046 0.000
K83.0 Cholangitis
0.954 0.046 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.953 0.047 0.000
I05-I09 Chronic rheumatic heart diseases
0.953 0.047 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.953 0.047 0.000
M51.9 Intervertebral disk disorder, unspecified
0.953 0.047 0.000
N18.5 Chronic kidney disease, stage 5
0.952 0.048 0.000
M41.9 Scoliosis, unspecified
0.952 0.048 0.000
H65 Nonsuppurative otitis media
0.952 0.048 0.000
K12 Stomatitis and related lesions
0.952 0.048 0.000
K29.3 Chronic superficial gastritis
0.952 0.048 0.000
K36 Other appendicitis
0.952 0.048 0.000
J80 Adult respiratory distress syndrome
0.952 0.048 0.000
O36.6 Maternal care for excessive foetal growth
0.951 0.049 0.000
I35 Nonrheumatic aortic valve disorders
0.951 0.049 0.000
S22.4 Multiple fractures of ribs
0.950 0.050 0.000
I71 Aortic aneurysm and dissection
0.950 0.050 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.950 0.050 0.000
J09-J18 Influenza and pneumonia
0.949 0.051 0.000
G93 Other disorders of brain
0.949 0.051 0.000
M23.3 Other meniscus derangements
0.949 0.051 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.949 0.051 0.000
Z45 Adjustment and management of implanted device
0.948 0.052 0.000
R06.0 Dyspnoea
0.948 0.052 0.000
R44.3 Hallucinations, unspecified
0.947 0.053 0.000
Z87 Personal history of other diseases and conditions
0.947 0.053 0.000
I72 Other aneurysm
0.947 0.053 0.000
W00-W19 Falls
0.946 0.054 0.000
C50.2 Upper-inner quadrant of breast
0.946 0.054 0.000
H10-H13 Disorders of conjunctiva
0.945 0.055 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.945 0.055 0.000
O66 Other obstructed labour
0.945 0.055 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.944 0.056 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.944 0.056 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.944 0.056 0.000
B35-B49 Mycoses
0.944 0.056 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.944 0.056 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.944 0.056 0.000
T88.4 Failed or difficult intubation
0.943 0.057 0.000
M54.1 Radiculopathy
0.943 0.057 0.000
M25.4 Effusion of joint
0.942 0.058 0.000
Z97.4 Presence of external hearing-aid
0.942 0.058 0.000
S20 Superficial injury of thorax
0.941 0.059 0.000
K29.8 Duodenitis
0.941 0.059 0.000
I45 Other conduction disorders
0.941 0.059 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.941 0.059 0.000
I99 Other and unspecified disorders of circulatory system
0.941 0.059 0.000
K04 Diseases of pulp and periapical tissues
0.941 0.059 0.000
I35.1 Aortic (valve) insufficiency
0.941 0.059 0.000
I95.2 Hypotension due to drugs
0.940 0.060 0.000
H02.0 Entropion and trichiasis of eyelid
0.940 0.060 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.940 0.060 0.000
K14 Diseases of tongue
0.939 0.061 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.939 0.061 0.000
M79.7 Fibromyalgia
0.939 0.061 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.939 0.061 0.000
M65-M68 Disorders of synovium and tendon
0.939 0.061 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.938 0.062 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.938 0.062 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.937 0.063 0.000
R44.1 Visual hallucinations
0.936 0.064 0.000
K86.1 Other chronic pancreatitis
0.936 0.064 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.936 0.064 0.000
F33 Recurrent depressive disorder
0.935 0.065 0.000
S06.5 Traumatic subdural haemorrhage
0.935 0.065 0.000
Z90.0 Acquired absence of part of head and neck
0.935 0.065 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.934 0.066 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.934 0.066 0.000
I77 Other disorders of arteries and arterioles
0.934 0.066 0.000
K31 Other diseases of stomach and duodenum
0.934 0.066 0.000
J84 Other interstitial pulmonary diseases
0.933 0.067 0.000
Y52 Agents primarily affecting the cardiovascular system
0.931 0.069 0.000
S82 Fracture of lower leg, including ankle
0.931 0.069 0.000
S22.40 Multiple fractures of ribs (closed)
0.931 0.069 0.000
K85.9 Acute pancreatitis, unspecified
0.931 0.069 0.000
Q60-Q64 Congenital malformations of the urinary system
0.931 0.069 0.000
S89.9 Unspecified injury of lower leg
0.931 0.069 0.000
I87 Other disorders of veins
0.930 0.070 0.000
I34.1 Mitral (valve) prolapse
0.930 0.070 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.930 0.070 0.000
Z94.8 Other transplanted organ and tissue status
0.930 0.070 0.000
T91 Sequelae of injuries of neck and trunk
0.929 0.071 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.929 0.071 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.929 0.071 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.928 0.072 0.000
E27.1 Primary adrenocortical insufficiency
0.928 0.072 0.000
I67.2 Cerebral atherosclerosis
0.928 0.072 0.000
E04.2 Non-toxic multinodular goitre
0.928 0.072 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.927 0.073 0.000
K26.3 Acute without haemorrhage or perforation
0.927 0.073 0.000
E88 Other metabolic disorders
0.927 0.073 0.000
R44.0 Auditory hallucinations
0.927 0.073 0.000
R41.0 Disorientation, unspecified
0.926 0.074 0.000
V20-V29 Motorcycle rider injured in transport accident
0.925 0.075 0.000
I33 Acute and subacute endocarditis
0.925 0.075 0.000
M48.09 Spinal stenosis (Site unspecified)
0.925 0.075 0.000
K37 Unspecified appendicitis
0.925 0.075 0.000
M54.3 Sciatica
0.924 0.076 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.924 0.076 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.924 0.076 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.924 0.076 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.923 0.077 0.000
N18.2 Chronic kidney disease, stage 2
0.923 0.077 0.000
K04.6 Periapical abscess with sinus
0.923 0.077 0.000
M47.2 Other spondylosis with radiculopathy
0.923 0.077 0.000
K75 Other inflammatory liver diseases
0.922 0.078 0.000
E04.0 Non-toxic diffuse goitre
0.922 0.078 0.000
H55 Nystagmus and other irregular eye movements
0.922 0.078 0.000
K46 Unspecified abdominal hernia
0.922 0.078 0.000
E10-E14 Diabetes mellitus
0.922 0.078 0.000
Z30 Contraceptive management
0.922 0.078 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.922 0.078 0.000
L81.4 Other melanin hyperpigmentation
0.922 0.078 0.000
S60 Superficial injury of wrist and hand
0.921 0.079 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.921 0.079 0.000
E87.6 Hypokalaemia
0.920 0.080 0.000
Y57 Other and unspecified drugs and medicaments
0.920 0.080 0.000
H93 Other disorders of ear, not elsewhere classified
0.919 0.081 0.000
O36.5 Maternal care for poor foetal growth
0.919 0.081 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.919 0.081 0.000
H18 Other disorders of cornea
0.919 0.081 0.000
K86.2 Cyst of pancreas
0.919 0.081 0.000
H74 Other disorders of middle ear and mastoid
0.919 0.081 0.000
R02 Gangrene, not elsewhere classified
0.918 0.082 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.918 0.082 0.000
I81 Portal vein thrombosis
0.918 0.082 0.000
K25 Gastric ulcer
0.918 0.082 0.000
I38 Endocarditis, valve unspecified
0.918 0.082 0.000
Z49 Care involving dialysis
0.918 0.082 0.000
N05 Unspecified nephritic syndrome
0.917 0.083 0.000
R63.0 Anorexia
0.917 0.083 0.000
F20 Schizophrenia
0.917 0.083 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.917 0.083 0.000
M25.86 Other specified joint disorders (Lower leg)
0.917 0.083 0.000
H90 Conductive and sensorineural hearing loss
0.916 0.084 0.000
J98.1 Pulmonary collapse
0.916 0.084 0.000
L29.2 Pruritus vulvae
0.916 0.084 0.000
M34.9 Systemic sclerosis, unspecified
0.915 0.085 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.915 0.085 0.000
I51 Complications and ill-defined descriptions of heart disease
0.915 0.085 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.915 0.085 0.000
Z71.3 Dietary counselling and surveillance
0.914 0.086 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.914 0.086 0.000
M65 Synovitis and tenosynovitis
0.914 0.086 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.914 0.086 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.914 0.086 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.913 0.087 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.913 0.087 0.000
K21 Gastro-oesophageal reflux disease
0.913 0.087 0.000
F32.0 Mild depressive episode
0.913 0.087 0.000
K45 Other abdominal hernia
0.913 0.087 0.000
S27 Injury of other and unspecified intrathoracic organs
0.913 0.087 0.000
M31 Other necrotising vasculopathies
0.912 0.088 0.000
S81.9 Open wound of lower leg, part unspecified
0.912 0.088 0.000
E04.1 Non-toxic single thyroid nodule
0.912 0.088 0.000
M47.89 Other spondylosis (Site unspecified)
0.912 0.088 0.000
Z99.2 Dependence on renal dialysis
0.912 0.088 0.000
I85 Oesophageal varices
0.912 0.088 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.911 0.089 0.000
T66-T78 Other and unspecified effects of external causes
0.910 0.090 0.000
M24 Other specific joint derangements
0.910 0.090 0.000
L81.9 Disorder of pigmentation, unspecified
0.910 0.090 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.910 0.090 0.000
J32.8 Other chronic sinusitis
0.909 0.091 0.000
E87.3 Alkalosis
0.909 0.091 0.000
H53-H54 Visual disturbances and blindness
0.909 0.091 0.000
T92 Sequelae of injuries of upper limb
0.908 0.092 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.908 0.092 0.000
Z36.8 Other antenatal screening
0.908 0.092 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.908 0.092 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.908 0.092 0.000
N03 Chronic nephritic syndrome
0.908 0.092 0.000
K85.1 Biliary acute pancreatitis
0.907 0.093 0.000
K70 Alcoholic liver disease
0.906 0.094 0.000
Y44 Agents primarily affecting blood constituents
0.906 0.094 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.906 0.094 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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