TreeWAS – Variant ID: rs11746865

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Z86 Personal history of certain other diseases	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
M54 Dorsalgia	0.999	0.001
M70-M79 Other soft tissue disorders	0.999	0.001
Chapter X Diseases of the respiratory system	0.998	0.002
Z92 Personal history of medical treatment	0.998	0.002
M79 Other soft tissue disorders, not elsewhere classified	0.997	0.003
M54.5 Low back pain	0.997	0.003
Z00-Z13 Persons encountering health services for examination and investigation	0.995	0.005
M79.6 Pain in limb	0.995	0.005
Chapter IX Diseases of the circulatory system	0.995	0.005
Z92.2 Personal history of long-term (current) use of other medicaments	0.994	0.006
Z86.1 Personal history of infectious and parasitic diseases	0.994	0.006
Chapter VII Diseases of the eye and adnexa	0.993	0.007
R50-R69 General symptoms and signs	0.992	0.008
J40-J47 Chronic lower respiratory diseases	0.991	0.009
M79.66 Pain in limb (Lower leg)	0.989	0.011
Chapter XI Diseases of the digestive system	0.983	0.017
M54.59 Low back pain (Site unspecified)	0.983	0.017
Z86.7 Personal history of diseases of the circulatory system	0.982	0.018
M20-M25 Other joint disorders	0.982	0.018
Z03 Medical observation and evaluation for suspected diseases and conditions	0.980	0.020
R51 Headache	0.979	0.021
Z86.6 Personal history of diseases of the nervous system and sense organs	0.977	0.023
J44 Other chronic obstructive pulmonary disease	0.976	0.024
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.972	0.028
Chapter V Mental and behavioural disorders	0.967	0.033
M23 Internal derangement of knee	0.964	0.036
Z13 Special screening examination for other diseases and disorders	0.962	0.038
Z87 Personal history of other diseases and conditions	0.956	0.044
I70-I79 Diseases of arteries, arterioles and capillaries	0.953	0.047
Z40-Z54 Persons encountering health services for specific procedures and health care	0.948	0.052
K35-K38 Diseases of appendix	0.944	0.056
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.943	0.057
M23.2 Derangement of meniscus due to old tear or injury	0.940	0.060
I60-I69 Cerebrovascular diseases	0.940	0.060
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.934	0.066
Chapter IV Endocrine, nutritional and metabolic diseases	0.933	0.067
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.932	0.068
Z87.1 Personal history of diseases of the digestive system	0.931	0.069
Z13.9 Special screening examination, unspecified	0.929	0.071
Z92.1 Personal history of long-term (current) use of anticoagulants	0.928	0.072
R11 Nausea and vomiting	0.927	0.073
R50 Fever of unknown origin	0.919	0.081
Chapter I Certain infectious and parasitic diseases	0.916	0.084
Z03.1 Observation for suspected malignant neoplasm	0.915	0.085
J43 Emphysema	0.914	0.086
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.913	0.087
K55-K64 Other diseases of intestines	0.913	0.087
Chapter XV Pregnancy, childbirth and the puerperium	0.911	0.089
Z70-Z76 Persons encountering health services in other circumstances	0.910	0.090
K35 Acute appendicitis	0.909	0.091
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.906	0.094
M79.62 Pain in limb (Upper arm)	0.901	0.099
M54.56 Low back pain (Lumbar region)	0.896	0.104
J30-J39 Other diseases of upper respiratory tract	0.895	0.105
R47-R49 Symptoms and signs involving speech and voice	0.894	0.106
J20-J22 Other acute lower respiratory infections	0.892	0.108
R10 Abdominal and pelvic pain	0.892	0.108
M51 Other intervertebral disk disorders	0.888	0.112
M54.3 Sciatica	0.888	0.112
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.888	0.112
I30-I52 Other forms of heart disease	0.887	0.113
B95-B98 Bacterial, viral and other infectious agents	0.886	0.114
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.886	0.114
H55-H59 Other disorders of eye and adnexa	0.886	0.114
M25 Other joint disorders, not elsewhere classified	0.886	0.114
Z91 Personal history of risk-factors, not elsewhere classified	0.885	0.115
H53-H54 Visual disturbances and blindness	0.883	0.117
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.881	0.119
Z86.4 Personal history of psychoactive substance abuse	0.879	0.121
Z53 Persons encountering health services for specifie procedures, not carried out	0.878	0.122
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.876	0.124
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.874	0.126
I77 Other disorders of arteries and arterioles	0.874	0.126
Chapter XX External causes of morbidity and mortality	0.874	0.126
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.874	0.126
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.870	0.130
Z03.8 Observation for other suspected diseases and conditions	0.867	0.133
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.865	0.135
H10-H13 Disorders of conjunctiva	0.864	0.136
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.862	0.138
M54.57 Low back pain (Lumbosacral region)	0.862	0.138
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.860	0.140
J43.9 Emphysema, unspecified	0.860	0.140
K55 Vascular disorders of intestine	0.859	0.141
R52 Pain, not elsewhere classified	0.859	0.141
K20-K31 Diseases of oesophagus, stomach and duodenum	0.859	0.141
M45-M49 Spondylopathies	0.857	0.143
R50.9 Fever, unspecified	0.857	0.143
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.857	0.143
M75 Shoulder lesions	0.853	0.147
T36-T50 Poisoning by drugs, medicaments and biological substances	0.850	0.150
J34 Other disorders of nose and nasal sinuses	0.849	0.151
R12 Heartburn	0.848	0.152
I34 Nonrheumatic mitral valve disorders	0.847	0.153
K62 Other diseases of anus and rectum	0.847	0.153
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.847	0.153
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.846	0.154
R56 Convulsions, not elsewhere classified	0.844	0.156
Z94 Transplanted organ and tissue status	0.844	0.156
K35.0 Acute appendicitis with generalised peritonitis	0.843	0.157
Z80 Family history of malignant neoplasm	0.842	0.158
F20 Schizophrenia	0.842	0.158
E00-E07 Disorders of thyroid gland	0.841	0.159
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.841	0.159
Z53.0 Procedure not carried out because of contraindication	0.837	0.163
Z97 Presence of other devices	0.836	0.164
Z03.4 Observation for suspected myocardial infarction	0.836	0.164
I67 Other cerebrovascular diseases	0.836	0.164
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.835	0.165
Z46 Fitting and adjustment of other devices	0.833	0.167
J44.9 Chronic obstructive pulmonary disease, unspecified	0.831	0.169
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.830	0.170
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.829	0.171
Z52 Donors of organs and tissues	0.827	0.173
I95-I99 Other and unspecified disorders of the circulatory system	0.826	0.174
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.825	0.175
R53 Malaise and fatigue	0.825	0.175
M79.8 Other specified soft tissue disorders	0.820	0.180
K36 Other appendicitis	0.819	0.181
Z45 Adjustment and management of implanted device	0.818	0.182
Z11 Special screening examination for infectious and parasitic diseases	0.816	0.184
Z90 Acquired absence of organs, not elsewhere classified	0.816	0.184
J22 Unspecified acute lower respiratory infection	0.816	0.184
M54.9 Dorsalgia, unspecified	0.816	0.184
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.816	0.184
O20-O29 Other maternal disorders predominantly related to pregnancy	0.813	0.187
Chapter II Neoplasms	0.812	0.188
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.812	0.188
I34.0 Mitral (valve) insufficiency	0.810	0.190
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.810	0.190
K90-K93 Other diseases of the digestive system	0.809	0.191
R10.4 Other and unspecified abdominal pain	0.809	0.191
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.806	0.194
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.805	0.195
R49 Voice disturbances	0.803	0.197
K35.9 Acute appendicitis, unspecified	0.803	0.197
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.802	0.198
I10-I15 Hypertensive diseases	0.801	0.199
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.801	0.199
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.799	0.201
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.798	0.202
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.798	0.202
T81 Complications of procedures, not elsewhere classified	0.798	0.202
R22.1 Localised swelling, mass and lump, neck	0.795	0.205
O60-O75 Complications of labour and delivery	0.795	0.205
Z92.6 Personal history of chemotherapy for neoplastic disease	0.794	0.206
S90-S99 Injuries to the ankle and foot	0.793	0.206
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.793	0.207
I63 Cerebral infarction	0.792	0.208
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.792	0.208
I74 Arterial embolism and thrombosis	0.791	0.209
J34.8 Other specified disorders of nose and nasal sinuses	0.791	0.209
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.787	0.213
M54.39 Sciatica (Site unspecified)	0.787	0.213
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.786	0.214
T15-T19 Effects of foreign body entering through natural orifice	0.784	0.215
R87 Abnormal findings in specimens from female genital organs	0.784	0.216
K55.0 Acute vascular disorders of intestine	0.784	0.216
F30-F39 Mood [affective] disorders	0.784	0.216
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.784	0.216
M79.65 Pain in limb (Pelvic region and thigh)	0.782	0.218
M79.7 Fibromyalgia	0.782	0.218
M23.5 Chronic instability of knee	0.780	0.220
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.780	0.220
I51 Complications and ill-defined descriptions of heart disease	0.778	0.222
M25.4 Effusion of joint	0.777	0.223
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.776	0.224
M50 Cervical disk disorders	0.775	0.225
R10.3 Pain localised to other parts of lower abdomen	0.774	0.226
M91-M94 Chondropathies	0.774	0.226
E70-E90 Metabolic disorders	0.774	0.226
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.774	0.226
Z53.9 Procedure not carried out, unspecified reason	0.773	0.227
F20.9 Schizophrenia, unspecified	0.773	0.227
Z98 Other postsurgical states	0.773	0.227
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.772	0.228
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.772	0.228
T81.3 Disruption of operation wound, not elsewhere classified	0.772	0.228
Z90.7 Acquired absence of genital organ(s)	0.771	0.229
Z03.3 Observation for suspected nervous system disorder	0.770	0.230
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.769	0.231
K31 Other diseases of stomach and duodenum	0.769	0.231
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.767	0.232
M25.8 Other specified joint disorders	0.766	0.234
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.765	0.235
R22.4 Localised swelling, mass and lump, lower limb	0.764	0.236
F40-F48 Neurotic, stress-related and somatoform disorders	0.764	0.236
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.764	0.236
M79.64 Pain in limb (Hand)	0.763	0.237
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.761	0.239
I60 Subarachnoid haemorrhage	0.760	0.240
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.758	0.242
M54.6 Pain in thoracic spine	0.757	0.243
M23.4 Loose body in knee	0.757	0.243
I69 Sequelae of cerebrovascular disease	0.756	0.244
Z04 Examination and observation for other reasons	0.756	0.244
M71 Other bursopathies	0.755	0.245
I73 Other peripheral vascular diseases	0.754	0.245
D69 Purpura and other haemorrhagic conditions	0.754	0.246
Z93 Artificial opening status	0.753	0.247
I77.6 Arteritis, unspecified	0.752	0.248
Z03.9 Observation for suspected disease or condition, unspecified	0.752	0.248
K56 Paralytic ileus and intestinal obstruction without hernia	0.752	0.248
H54 Blindness and low vision	0.752	0.248
Z46.6 Fitting and adjustment of urinary device	0.751	0.249
K62.7 Radiation proctitis	0.750	0.250
M80-M85 Disorders of bone density and structure	0.749	0.251
H02 Other disorders of eyelid	0.748	0.252
Z45.8 Adjustment and management of other implanted devices	0.747	0.253
K62.8 Other specified diseases of anus and rectum	0.747	0.253
M47 Spondylosis	0.746	0.254
H50 Other strabismus	0.745	0.255
K27 Peptic ulcer, site unspecified	0.745	0.255
O20 Haemorrhage in early pregnancy	0.743	0.257
R52.1 Chronic intractable pain	0.742	0.258
R61 Hyperhidrosis	0.741	0.258
H10 Conjunctivitis	0.741	0.259
Z52.4 Kidney donor	0.740	0.260
R56.8 Other and unspecified convulsions	0.738	0.262
R49.0 Dysphonia	0.738	0.262
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.737	0.263
M51.8 Other specified intervertebral disk disorders	0.737	0.263
M79.60 Pain in limb (Multiple sites)	0.736	0.264
M51.9 Intervertebral disk disorder, unspecified	0.736	0.264
E04 Other non-toxic goitre	0.736	0.264
M15-M19 Arthrosis	0.736	0.264
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.736	0.264
I51.8 Other ill-defined heart diseases	0.735	0.265
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.735	0.265
J34.3 Hypertrophy of nasal turbinates	0.735	0.265
A30-A49 Other bacterial diseases	0.735	0.265
Z50 Care involving use of rehabilitation procedures	0.735	0.265
J80-J84 Other respiratory diseases principally affecting the interstitium	0.735	0.265
K12 Stomatitis and related lesions	0.734	0.266
H04 Disorders of lachrymal system	0.733	0.267
Z73 Problems related to life-management difficulty	0.733	0.267
H53 Visual disturbances	0.733	0.267
H55 Nystagmus and other irregular eye movements	0.733	0.267
I77.8 Other specified disorders of arteries and arterioles	0.732	0.268
K11 Diseases of salivary glands	0.732	0.268
E87 Other disorders of fluid, electrolyte and acid-base balance	0.732	0.268
M86-M90 Other osteopathies	0.731	0.269
Z71.9 Counselling, unspecified	0.731	0.269
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.731	0.269
H40-H42 Glaucoma	0.731	0.269
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.731	0.269
M65-M68 Disorders of synovium and tendon	0.730	0.270
C77.3 Axillary and upper limb lymph nodes	0.730	0.270
H18 Other disorders of cornea	0.730	0.270
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.730	0.270
J60-J70 Lung diseases due to external agents	0.729	0.271
C77.2 Intra-abdominal lymph nodes	0.729	0.271
F22 Persistent delusional disorders	0.728	0.272
M77 Other enthesopathies	0.727	0.273
R06 Abnormalities of breathing	0.727	0.273
M75.0 Adhesive capsulitis of shoulder	0.727	0.273
I67.9 Cerebrovascular disease, unspecified	0.726	0.274
T85 Complications of other internal prosthetic devices, implants and grafts	0.724	0.276
Z51 Other medical care	0.724	0.276
S20-S29 Injuries to the thorax	0.723	0.277
D68 Other coagulation defects	0.723	0.277
R87.6 Abnormal cytological findings	0.720	0.280
F25 Schizoaffective disorders	0.719	0.281
Z22 Carrier of infectious disease	0.719	0.281
H16 Keratitis	0.719	0.281
H52 Disorders of refraction and accommodation	0.718	0.282
K55.2 Angiodysplasia of colon	0.718	0.282
D70-D77 Other diseases of blood and blood-forming organs	0.717	0.282
Z89 Acquired absence of limb	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
J40 Bronchitis, not specified as acute or chronic	0.717	0.283
M53 Other dorsopathies, not elsewhere classified	0.717	0.283
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.717	0.283
M76 Enthesopathies of lower limb, excluding foot	0.716	0.284
M73 Soft tissue disorders in diseases classified elsewhere	0.716	0.284
M54.8 Other dorsalgia	0.716	0.284
M54.4 Lumbago with sciatica	0.716	0.284
M54.0 Panniculitis affecting regions of neck and back	0.716	0.284
Z92.9 Personal history of medical treatment, unspecified	0.715	0.285
Z92.8 Personal history of other medical treatment	0.715	0.285
Z92.5 Personal history of rehabilitation measures	0.715	0.285
Z92.0 Personal history of contraception	0.715	0.285
I35 Nonrheumatic aortic valve disorders	0.715	0.285
M79.9 Soft tissue disorder, unspecified	0.715	0.285
M79.5 Residual foreign body in soft tissue	0.715	0.285
M79.4 Hypertrophy of (infrapatellar) fat pad	0.715	0.285
M79.3 Panniculitis, unspecified	0.715	0.285
M79.2 Neuralgia and neuritis, unspecified	0.715	0.285
M79.1 Myalgia	0.715	0.285
M54.55 Low back pain (Thoracolumbar region)	0.715	0.285
M54.54 Low back pain-Thoracic	0.715	0.285
M54.53 Low back pain-Cervicothoracic	0.715	0.285
M54.52 Low back pain-Cervical	0.715	0.285
M54.51 Low back pain-Occipit-atl-axl	0.715	0.285
M54.50 Low back pain (Multiple sites in spine)	0.715	0.285
I30 Acute pericarditis	0.714	0.286
Z80.4 Family history of malignant neoplasm of genital organs	0.714	0.286
M70 Soft tissue disorders related to use, overuse and pressure	0.714	0.286
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.714	0.286
I63.9 Cerebral infarction, unspecified	0.714	0.286
Z10 Routine general health check-up of defined subpopulation	0.713	0.286
M79.68 Pain in limb (Other)	0.713	0.287
M79.63 Pain in limb (Forearm)	0.713	0.287
M79.61 Pain in limb (Shoulder region)	0.713	0.287
I00-I02 Acute rheumatic fever	0.713	0.287
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.713	0.287
M35 Other systemic involvement of connective tissue	0.713	0.287
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.713	0.287
H46-H48 Disorders of optic nerve and visual pathways	0.712	0.288
J44.8 Other specified chronic obstructive pulmonary disease	0.712	0.288
O00-O08 Pregnancy with abortive outcome	0.711	0.289
R68 Other general symptoms and signs	0.711	0.289
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.711	0.289
R62 Lack of expected normal physiological development	0.711	0.289
R57 Shock, not elsewhere classified	0.711	0.289
R64 Cachexia	0.711	0.289
R58 Haemorrhage, not elsewhere classified	0.711	0.289
R74 Abnormal serum enzyme levels	0.711	0.289
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.711	0.289
M79.67 Pain in limb (Ankle and foot)	0.710	0.289
I45 Other conduction disorders	0.711	0.289
J41 Simple and mucopurulent chronic bronchitis	0.710	0.290
J42 Unspecified chronic bronchitis	0.710	0.290
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.710	0.290
Chapter VIII Diseases of the ear and mastoid process	0.709	0.291
S50-S59 Injuries to the elbow and forearm	0.709	0.291
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.709	0.291
M54.1 Radiculopathy	0.709	0.291
K22 Other diseases of oesophagus	0.708	0.292
J95-J99 Other diseases of the respiratory system	0.708	0.292
K62.0 Anal polyp	0.706	0.294
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.704	0.296
M34 Systemic sclerosis	0.704	0.296
M33 Dermatopolymyositis	0.704	0.296
M32 Systemic lupus erythematosus	0.704	0.296
M30 Polyarteritis nodosa and related conditions	0.704	0.296
M21 Other acquired deformities of limbs	0.704	0.296
W00-W19 Falls	0.704	0.296
E05 Thyrotoxicosis [hyperthyroidism]	0.703	0.297
Z03.6 Observation for suspected toxic effect from ingested substance	0.703	0.297
Z03.2 Observation for suspected mental and behavioural disorders	0.703	0.297
Z03.0 Observation for suspected tuberculosis	0.703	0.297
Z97.5 Presence of (intra-uterine) contraceptive device	0.702	0.298
B90-B94 Sequelae of infectious and parasitic diseases	0.702	0.298
M51.2 Other specified intervertebral disk displacement	0.701	0.299
Z87.4 Personal history of diseases of the genito-urinary system	0.701	0.299
I70 Atherosclerosis	0.700	0.300
Z83 Family history of other specific disorders	0.700	0.300
M25.46 Effusion of joint (Lower leg)	0.700	0.300
I72 Other aneurysm	0.699	0.301
K61 Abscess of anal and rectal regions	0.699	0.301
R50.0 Fever with chills	0.698	0.302
I71 Aortic aneurysm and dissection	0.697	0.303
R05 Cough	0.697	0.303
T79-T79 Certain early complications of trauma	0.696	0.303
T33-T35 Frostbite	0.696	0.303
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.696	0.303
T26-T28 Burns and corrosions confined to eye and internal organs	0.696	0.303
T20-T25 Burns and corrosions of external body surface, specified by site	0.696	0.303
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.303
T00-T07 Injuries involving multiple body regions	0.696	0.303
S10-S19 Injuries to the neck	0.696	0.303
Chapter XXII Codes for special purposes	0.696	0.304
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.696	0.304
Z49 Care involving dialysis	0.696	0.304
T43.2 Other and unspecified antidepressants	0.695	0.305
T88 Other complications of surgical and medical care, not elsewhere classified	0.695	0.305
J47 Bronchiectasis	0.695	0.305
Z72 Problems related to lifestyle	0.695	0.305
F99-F99 Unspecified mental disorder	0.693	0.307
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.693	0.307
F80-F89 Disorders of psychological development	0.693	0.307
F70-F79 Mental retardation	0.693	0.307
F60-F69 Disorders of adult personality and behaviour	0.693	0.307
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.693	0.307
J36 Peritonsillar abscess	0.693	0.307
R79 Other abnormal findings of blood chemistry	0.693	0.307
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.692	0.308
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.692	0.308
M54.36 Sciatica (Lumbar region)	0.691	0.308
I62 Other nontraumatic intracranial haemorrhage	0.691	0.308
M23.9 Internal derangement of knee, unspecified	0.691	0.309
M23.6 Other spontaneous disruption of ligament(s) of knee	0.691	0.309
M23.1 Discoid meniscus (congenital)	0.691	0.309
M23.0 Cystic meniscus	0.691	0.309
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.690	0.310
Z13.8 Special screening examination for other specified diseases and disorders	0.690	0.310
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.690	0.310
Z13.5 Special screening examination for eye and ear disorders	0.690	0.310
Z13.4 Special screening examination for certain developmental disorders in childhood	0.690	0.310
Z13.3 Special screening examination for mental and behavioural disorders	0.690	0.310
Z13.2 Special screening examination for nutritional disorders	0.690	0.310
Z13.1 Special screening examination for diabetes mellitus	0.690	0.310
H21 Other disorders of iris and ciliary body	0.689	0.311
R73 Elevated blood glucose level	0.689	0.311
M72 Fibroblastic disorders	0.689	0.311
D80-D89 Certain disorders involving the immune mechanism	0.689	0.311
M75.3 Calcific tendinitis of shoulder	0.689	0.311
Z87.8 Personal history of other specified conditions	0.689	0.311
Z98.8 Other specified postsurgical states	0.688	0.312
E87.5 Hyperkalaemia	0.688	0.312
Z99.1 Dependence on respirator	0.687	0.313
J45 Asthma	0.687	0.313
Z87.6 Personal history of certain conditions arising in the perinatal period	0.685	0.314
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.685	0.314
R47 Speech disturbances, not elsewhere classified	0.685	0.315
Y95 Nosocomial condition	0.685	0.315
M17 Gonarthrosis [arthrosis of knee]	0.685	0.315
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.683	0.316
M25.6 Stiffness of joint, not elsewhere classified	0.683	0.317
K21 Gastro-oesophageal reflux disease	0.683	0.317
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.683	0.317
E20-E35 Disorders of other endocrine glands	0.682	0.318
Z80.5 Family history of malignant neoplasm of urinary tract	0.682	0.318
R52.9 Pain, unspecified	0.681	0.318
H11 Other disorders of conjunctiva	0.681	0.319
I78 Diseases of capillaries	0.681	0.319
K05 Gingivitis and periodontal diseases	0.681	0.319
M23.3 Other meniscus derangements	0.681	0.319
H02.9 Disorder of eyelid, unspecified	0.681	0.319
Z48 Other surgical follow-up care	0.680	0.319
Z54 Convalescence	0.680	0.320
Z44 Fitting and adjustment of external prosthetic device	0.680	0.320
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.680	0.320
R22.2 Localised swelling, mass and lump, trunk	0.679	0.321
J00-J06 Acute upper respiratory infections	0.679	0.321
J39 Other diseases of upper respiratory tract	0.678	0.321
H30-H36 Disorders of choroid and retina	0.678	0.322
S00-S09 Injuries to the head	0.677	0.323
K38 Other diseases of appendix	0.677	0.323
R41 Other symptoms and signs involving cognitive functions and awareness	0.677	0.323
O70 Perineal laceration during delivery	0.676	0.324
F17 Mental and behavioural disorders due to use of tobacco	0.676	0.324
I12 Hypertensive renal disease	0.676	0.324
Z75 Problems related to medical facilities and other health care	0.676	0.324
M22 Disorders of patella	0.676	0.324
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.676	0.324
Z57 Occupational exposure to risk-factors	0.676	0.324
Z29 Need for other prophylactic measures	0.675	0.324
R06.0 Dyspnoea	0.675	0.325
K35.8 Acute appendicitis, other and unspecified	0.675	0.325
R63 Symptoms and signs concerning food and fluid intake	0.675	0.325
C77.4 Inguinal and lower limb lymph nodes	0.674	0.325
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.674	0.326
I68 Cerebrovascular disorders in diseases classified elsewhere	0.674	0.326
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.674	0.326
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.674	0.326
M24 Other specific joint derangements	0.674	0.326
R10.0 Acute abdomen	0.673	0.327
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.673	0.327
H53.2 Diplopia	0.673	0.327
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.672	0.327
I77.1 Stricture of artery	0.673	0.327
M75.1 Rotator cuff syndrome	0.672	0.328
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.672	0.328
I67.8 Other specified cerebrovascular diseases	0.672	0.328
Z11.2 Special screening examination for other bacterial diseases	0.672	0.328
M23.8 Other internal derangements of knee	0.671	0.329
H59.8 Other postprocedural disorders of eye and adnexa	0.671	0.329
Z94.7 Corneal transplant status	0.671	0.329
T87 Complications peculiar to reattachment and amputation	0.670	0.330
T86 Failure and rejection of transplanted organs and tissues	0.670	0.330
T80 Complications following infusion, transfusion and therapeutic injection	0.670	0.330
E40-E46 Malnutrition	0.669	0.331
R10.2 Pelvic and perineal pain	0.669	0.331
E50-E64 Other nutritional deficiencies	0.668	0.332
S80-S89 Injuries to the knee and lower leg	0.668	0.332
B97 Viral agents as the cause of diseases classified to other chapters	0.668	0.332
K31.9 Disease of stomach and duodenum, unspecified	0.668	0.332
Z71.3 Dietary counselling and surveillance	0.668	0.332
E10-E14 Diabetes mellitus	0.668	0.332
I95 Hypotension	0.668	0.332
K35.3 Acute appendicitis with localized peritonitis	0.666	0.334
D69.6 Thrombocytopenia, unspecified	0.666	0.334
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.666	0.334
M79.86 Other specified soft tissue disorders (Lower leg)	0.666	0.334
C51-C58 Malignant neoplasms of female genital organs	0.665	0.335
J90-J94 Other diseases of pleura	0.664	0.336
Z94.8 Other transplanted organ and tissue status	0.664	0.336
Z13.6 Special screening examination for cardiovascular disorders	0.664	0.336
F20.0 Paranoid schizophrenia	0.664	0.336
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.663	0.337
I34.1 Mitral (valve) prolapse	0.663	0.337
K62.4 Stenosis of anus and rectum	0.663	0.337
O20.9 Haemorrhage in early pregnancy, unspecified	0.662	0.338
K62.1 Rectal polyp	0.661	0.339
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.660	0.340
J86 Pyothorax	0.659	0.341

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations