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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0042
log Bayes Factor = 307.243
contains 12 variants:
rs115729723
lBF = 16.308
Chr 1 : 34,410,093
rs75655068
lBF = 13.577
Chr 7 : 92,658,364
rs78586881
lBF = 15.301
Chr 8 : 37,144,739
rs117825839
lBF = 16.538
Chr12 : 28,978,196
rs75876943
lBF = 15.005
Chr12 : 86,555,845
rs117487501
lBF = 16.208
Chr14 : 26,589,434
rs191800091
lBF = 14.833
Chr14 : 27,245,961
rs17393098
lBF = 26.526
Chr14 : 34,025,230
rs116911364
lBF = 17.510
Chr14 : 93,276,446
rs117453948
lBF = 17.548
Chr16 : 77,965,459
rs116996274
lBF = 16.875
Chr17 : 72,204,105
rs112888289
lBF = 14.865
Chr19 : 31,600,124
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C78.0 Secondary malignant neoplasm of lung
1.000 0.000 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
1.000 0.000 0.000
G93 Other disorders of brain
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
R50 Fever of unknown origin
1.000 0.000 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
S20-S29 Injuries to the thorax
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R51 Headache
1.000 0.000 0.000
Z51.5 Palliative care
1.000 0.000 0.000
I63 Cerebral infarction
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
C78.7 Secondary malignant neoplasm of liver
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
K70 Alcoholic liver disease
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
R53 Malaise and fatigue
1.000 0.000 0.000
Y43.3 Other antineoplastic drugs
1.000 0.000 0.000
R06 Abnormalities of breathing
1.000 0.000 0.000
Y43 Primarily systemic agents
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
I51 Complications and ill-defined descriptions of heart disease
1.000 0.000 0.000
S27 Injury of other and unspecified intrathoracic organs
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
R50.9 Fever, unspecified
1.000 0.000 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
H65-H75 Diseases of middle ear and mastoid
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
I67 Other cerebrovascular diseases
1.000 0.000 0.000
I51.9 Heart disease, unspecified
1.000 0.000 0.000
I50.9 Heart failure, unspecified
1.000 0.000 0.000
I67.9 Cerebrovascular disease, unspecified
1.000 0.000 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
1.000 0.000 0.000
A41 Other septicaemia
1.000 0.000 0.000
I22 Subsequent myocardial infarction
1.000 0.000 0.000
I87 Other disorders of veins
1.000 0.000 0.000
Z93 Artificial opening status
1.000 0.000 0.000
H80.9 Otosclerosis, unspecified
0.999 0.001 0.000
C78.2 Secondary malignant neoplasm of pleura
0.999 0.001 0.000
Z43 Attention to artificial openings
0.999 0.001 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
H80-H83 Diseases of inner ear
0.999 0.001 0.000
H80 Otosclerosis
0.999 0.001 0.000
H53-H54 Visual disturbances and blindness
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
I49 Other cardiac arrhythmias
0.999 0.001 0.000
M84 Disorders of continuity of bone
0.999 0.001 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.999 0.001 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.999 0.001 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
H10-H13 Disorders of conjunctiva
0.999 0.001 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.999 0.001 0.000
G30-G32 Other degenerative diseases of the nervous system
0.999 0.001 0.000
R00.2 Palpitations
0.999 0.001 0.000
M54.57 Low back pain (Lumbosacral region)
0.999 0.001 0.000
M25.8 Other specified joint disorders
0.999 0.001 0.000
I69 Sequelae of cerebrovascular disease
0.999 0.001 0.000
I50.0 Congestive heart failure
0.999 0.001 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.999 0.001 0.000
D00-D09 In situ neoplasms
0.999 0.001 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.999 0.001 0.000
H25-H28 Disorders of lens
0.998 0.002 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.998 0.002 0.000
R52 Pain, not elsewhere classified
0.998 0.002 0.000
R50.8 Other specified fever
0.998 0.002 0.000
I20.0 Unstable angina
0.998 0.002 0.000
E20-E35 Disorders of other endocrine glands
0.998 0.002 0.000
S80-S89 Injuries to the knee and lower leg
0.998 0.002 0.000
M54.9 Dorsalgia, unspecified
0.998 0.002 0.000
I34 Nonrheumatic mitral valve disorders
0.998 0.002 0.000
A41.9 Septicaemia, unspecified
0.998 0.002 0.000
D03 Melanoma in situ
0.998 0.002 0.000
R00 Abnormalities of heart beat
0.998 0.002 0.000
S27.0 Traumatic pneumothorax
0.997 0.003 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.997 0.003 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.997 0.003 0.000
I05-I09 Chronic rheumatic heart diseases
0.997 0.003 0.000
W00-W19 Falls
0.997 0.003 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.997 0.003 0.000
S50-S59 Injuries to the elbow and forearm
0.997 0.003 0.000
M65-M68 Disorders of synovium and tendon
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
M51 Other intervertebral disk disorders
0.996 0.004 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.996 0.004 0.000
R06.0 Dyspnoea
0.996 0.004 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.996 0.004 0.000
M24 Other specific joint derangements
0.996 0.004 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.996 0.004 0.000
F32 Depressive episode
0.995 0.005 0.000
K83 Other diseases of biliary tract
0.995 0.005 0.000
Z95.1 Presence of aortocoronary bypass graft
0.995 0.005 0.000
S60-S69 Injuries to the wrist and hand
0.995 0.005 0.000
S06 Intracranial injury
0.995 0.005 0.000
K92.0 Haematemesis
0.995 0.005 0.000
O60-O75 Complications of labour and delivery
0.995 0.005 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.995 0.005 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.995 0.005 0.000
D70 Agranulocytosis
0.995 0.005 0.000
H53 Visual disturbances
0.995 0.005 0.000
H11 Other disorders of conjunctiva
0.994 0.006 0.000
R06.5 Mouth breathing
0.994 0.006 0.000
K90-K93 Other diseases of the digestive system
0.994 0.006 0.000
H26 Other cataract
0.994 0.006 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.994 0.006 0.000
K92 Other diseases of digestive system
0.993 0.007 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.993 0.007 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.993 0.007 0.000
C25 Malignant neoplasm of pancreas
0.993 0.007 0.000
M47.9 Spondylosis, unspecified
0.993 0.007 0.000
S01 Open wound of head
0.993 0.007 0.000
M77 Other enthesopathies
0.992 0.008 0.000
M86-M90 Other osteopathies
0.992 0.008 0.000
I87.8 Other specified disorders of veins
0.992 0.008 0.000
R45 Symptoms and signs involving emotional state
0.991 0.009 0.000
I72 Other aneurysm
0.991 0.009 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.991 0.009 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.991 0.009 0.000
I08 Multiple valve diseases
0.991 0.009 0.000
S02 Fracture of skull and facial bones
0.991 0.009 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.991 0.009 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.990 0.010 0.000
R44.1 Visual hallucinations
0.990 0.010 0.000
F31 Bipolar affective disorder
0.990 0.010 0.000
H30-H36 Disorders of choroid and retina
0.989 0.011 0.000
G93.4 Encephalopathy, unspecified
0.989 0.011 0.000
S10-S19 Injuries to the neck
0.989 0.011 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.989 0.011 0.000
M65 Synovitis and tenosynovitis
0.988 0.012 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.988 0.012 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.988 0.012 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.988 0.012 0.000
Z63 Other problems related to primary support group, including family circumstances
0.988 0.012 0.000
S80 Superficial injury of lower leg
0.988 0.012 0.000
C71 Malignant neoplasm of brain
0.987 0.013 0.000
M48 Other spondylopathies
0.987 0.013 0.000
Z29 Need for other prophylactic measures
0.987 0.013 0.000
I62 Other nontraumatic intracranial haemorrhage
0.987 0.013 0.000
G54 Nerve root and plexus disorders
0.987 0.013 0.000
K70.4 Alcoholic hepatic failure
0.987 0.013 0.000
C18 Malignant neoplasm of colon
0.987 0.013 0.000
D68 Other coagulation defects
0.986 0.014 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.986 0.014 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.986 0.014 0.000
W20-W49 Exposure to inanimate mechanical forces
0.986 0.014 0.000
Y86 Sequelae of other accidents
0.986 0.014 0.000
I34.0 Mitral (valve) insufficiency
0.985 0.015 0.000
I86 Varicose veins of other sites
0.985 0.015 0.000
I61 Intracerebral haemorrhage
0.985 0.015 0.000
Z43.1 Attention to gastrostomy
0.985 0.015 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.984 0.016 0.000
Chapter XXII Codes for special purposes
0.984 0.016 0.000
M84.0 Malunion of fracture
0.984 0.016 0.000
J11 Influenza, virus not identified
0.984 0.016 0.000
R47-R49 Symptoms and signs involving speech and voice
0.984 0.016 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.984 0.016 0.000
H74 Other disorders of middle ear and mastoid
0.983 0.017 0.000
K12 Stomatitis and related lesions
0.983 0.017 0.000
M22 Disorders of patella
0.983 0.017 0.000
K83.1 Obstruction of bile duct
0.983 0.017 0.000
R57 Shock, not elsewhere classified
0.983 0.017 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.983 0.017 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.981 0.019 0.000
H55-H59 Other disorders of eye and adnexa
0.981 0.019 0.000
S51 Open wound of forearm
0.981 0.019 0.000
G70-G73 Diseases of myoneural junction and muscle
0.981 0.019 0.000
M23 Internal derangement of knee
0.981 0.019 0.000
S90-S99 Injuries to the ankle and foot
0.980 0.020 0.000
K72 Hepatic failure, not elsewhere classified
0.980 0.020 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.980 0.020 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.980 0.020 0.000
Z51.3 Blood transfusion without reported diagnosis
0.979 0.021 0.000
C77.2 Intra-abdominal lymph nodes
0.979 0.021 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.979 0.021 0.000
M05-M14 Inflammatory polyarthropathies
0.978 0.022 0.000
S80.0 Contusion of knee
0.978 0.022 0.000
I20.8 Other forms of angina pectoris
0.978 0.022 0.000
C79.2 Secondary malignant neoplasm of skin
0.978 0.022 0.000
G93.6 Cerebral oedema
0.978 0.022 0.000
I24 Other acute ischaemic heart diseases
0.978 0.022 0.000
C25.9 Pancreas, unspecified
0.978 0.022 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.977 0.023 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.977 0.023 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.977 0.023 0.000
R41.3 Other amnesia
0.977 0.023 0.000
S05 Injury of eye and orbit
0.977 0.023 0.000
J10 Influenza due to identified influenza virus
0.977 0.023 0.000
K70.3 Alcoholic cirrhosis of liver
0.976 0.024 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.976 0.024 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.976 0.024 0.000
M15-M19 Arthrosis
0.975 0.025 0.000
I45 Other conduction disorders
0.975 0.025 0.000
K83.0 Cholangitis
0.975 0.025 0.000
M25.84 Other specified joint disorders (Hand)
0.975 0.025 0.000
I63.9 Cerebral infarction, unspecified
0.974 0.026 0.000
S02.1 Fracture of base of skull
0.974 0.026 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.974 0.026 0.000
G30 Alzheimer's disease
0.974 0.026 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.973 0.027 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.973 0.027 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.973 0.027 0.000
M84.03 Malunion of fracture (Forearm)
0.973 0.027 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.973 0.027 0.000
Z95.3 Presence of xenogenic heart valve
0.973 0.027 0.000
I86.1 Scrotal varices
0.973 0.027 0.000
G51 Facial nerve disorders
0.973 0.027 0.000
H66 Suppurative and unspecified otitis media
0.972 0.028 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.972 0.028 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.972 0.028 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.972 0.028 0.000
F32.0 Mild depressive episode
0.972 0.028 0.000
M25.3 Other instability of joint
0.971 0.029 0.000
K70.0 Alcoholic fatty liver
0.971 0.029 0.000
W18 Other fall on same level
0.971 0.029 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.971 0.029 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.971 0.029 0.000
G50 Disorders of trigeminal nerve
0.970 0.030 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.970 0.030 0.000
L60-L75 Disorders of skin appendages
0.970 0.030 0.000
J60-J70 Lung diseases due to external agents
0.970 0.030 0.000
I49.0 Ventricular fibrillation and flutter
0.970 0.030 0.000
A40 Streptococcal septicaemia
0.969 0.031 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.969 0.031 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.969 0.031 0.000
R01 Cardiac murmurs and other cardiac sounds
0.969 0.031 0.000
H26.4 After-cataract
0.968 0.032 0.000
H54 Blindness and low vision
0.968 0.032 0.000
H53.4 Visual field defects
0.968 0.032 0.000
M91-M94 Chondropathies
0.968 0.032 0.000
R40 Somnolence, stupor and coma
0.968 0.032 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.967 0.033 0.000
F80-F89 Disorders of psychological development
0.967 0.033 0.000
Chapter XIV Diseases of the genitourinary system
0.967 0.033 0.000
C22.1 Intrahepatic bile duct carcinoma
0.967 0.033 0.000
H60-H62 Diseases of external ear
0.966 0.034 0.000
Z96 Presence of other functional implants
0.966 0.034 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.966 0.034 0.000
R45.1 Restlessness and agitation
0.966 0.034 0.000
I69.3 Sequelae of cerebral infarction
0.966 0.034 0.000
I20.1 Angina pectoris with documented spasm
0.966 0.034 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.966 0.034 0.000
Z96.8 Presence of other specified functional implants
0.966 0.034 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.966 0.034 0.000
S62 Fracture at wrist and hand level
0.965 0.035 0.000
G82 Paraplegia and tetraplegia
0.965 0.035 0.000
W25 Contact with sharp glass
0.965 0.035 0.000
R57.2 Septic shock
0.965 0.035 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.965 0.035 0.000
I71 Aortic aneurysm and dissection
0.965 0.035 0.000
Z52 Donors of organs and tissues
0.965 0.035 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.964 0.036 0.000
M25.4 Effusion of joint
0.964 0.036 0.000
C79.6 Secondary malignant neoplasm of ovary
0.964 0.036 0.000
S89 Other and unspecified injuries of lower leg
0.964 0.036 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.964 0.036 0.000
M89 Other disorders of bone
0.964 0.036 0.000
H21 Other disorders of iris and ciliary body
0.964 0.036 0.000
I42 Cardiomyopathy
0.964 0.036 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.963 0.037 0.000
H90-H95 Other disorders of ear
0.963 0.037 0.000
F33 Recurrent depressive disorder
0.963 0.037 0.000
S02.10 Fracture of base of skull (closed)
0.963 0.037 0.000
C77.8 Lymph nodes of multiple regions
0.962 0.038 0.000
L60 Nail disorders
0.961 0.039 0.000
M23.5 Chronic instability of knee
0.961 0.039 0.000
K72.9 Hepatic failure, unspecified
0.961 0.039 0.000
T91 Sequelae of injuries of neck and trunk
0.960 0.040 0.000
H35 Other retinal disorders
0.960 0.040 0.000
G54.0 Brachial plexus disorders
0.960 0.040 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.960 0.040 0.000
S22.4 Multiple fractures of ribs
0.960 0.040 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.960 0.040 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.960 0.040 0.000
R47 Speech disturbances, not elsewhere classified
0.959 0.041 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.959 0.041 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.959 0.041 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.959 0.041 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.959 0.041 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.959 0.041 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.958 0.042 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.958 0.042 0.000
N76 Other inflammation of vagina and vulva
0.958 0.042 0.000
G83 Other paralytic syndromes
0.958 0.042 0.000
E22 Hyperfunction of pituitary gland
0.958 0.042 0.000
S12 Fracture of neck
0.957 0.043 0.000
M47.2 Other spondylosis with radiculopathy
0.957 0.043 0.000
S01.1 Open wound of eyelid and periocular area
0.957 0.043 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.957 0.043 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.957 0.043 0.000
S01.2 Open wound of nose
0.956 0.044 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.956 0.044 0.000
Z29.0 Isolation
0.956 0.044 0.000
R52.2 Other chronic pain
0.956 0.044 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.956 0.044 0.000
C17 Malignant neoplasm of small intestine
0.955 0.045 0.000
T82.3 Mechanical complication of other vascular grafts
0.954 0.046 0.000
G40-G47 Episodic and paroxysmal disorders
0.954 0.046 0.000
E28 Ovarian dysfunction
0.954 0.046 0.000
H10 Conjunctivitis
0.954 0.046 0.000
S90 Superficial injury of ankle and foot
0.953 0.047 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.953 0.047 0.000
B35-B49 Mycoses
0.953 0.047 0.000
G91 Hydrocephalus
0.953 0.047 0.000
Z43.3 Attention to colostomy
0.952 0.048 0.000
B15-B19 Viral hepatitis
0.952 0.048 0.000
Y40 Systemic antibiotics
0.952 0.048 0.000
S20 Superficial injury of thorax
0.952 0.048 0.000
R52.0 Acute pain
0.951 0.049 0.000
M51.9 Intervertebral disk disorder, unspecified
0.951 0.049 0.000
H53.2 Diplopia
0.951 0.049 0.000
U80 Agent resistant to penicillin and related antibiotics
0.951 0.049 0.000
D68.2 Hereditary deficiency of other clotting factors
0.951 0.049 0.000
O43 Placental disorders
0.950 0.050 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.950 0.050 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.950 0.050 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.950 0.050 0.000
S70-S79 Injuries to the hip and thigh
0.950 0.050 0.000
Z51.9 Medical care, unspecified
0.950 0.050 0.000
W25.9 Unspecified place
0.950 0.050 0.000
Y52 Agents primarily affecting the cardiovascular system
0.949 0.051 0.000
S64 Injury of nerves at wrist and hand level
0.949 0.051 0.000
G12 Spinal muscular atrophy and related syndromes
0.949 0.051 0.000
E27 Other disorders of adrenal gland
0.949 0.051 0.000
G50.0 Trigeminal neuralgia
0.949 0.051 0.000
R54 Senility
0.948 0.052 0.000
M47.1 Other spondylosis with myelopathy
0.948 0.052 0.000
I49.5 Sick sinus syndrome
0.948 0.052 0.000
C51-C58 Malignant neoplasms of female genital organs
0.948 0.052 0.000
M24.0 Loose body in joint
0.948 0.052 0.000
M16 Coxarthrosis [arthrosis of hip]
0.947 0.053 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.947 0.053 0.000
I60 Subarachnoid haemorrhage
0.946 0.054 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.946 0.054 0.000
Q80-Q89 Other congenital malformations
0.946 0.054 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.945 0.055 0.000
G72 Other myopathies
0.945 0.055 0.000
M06 Other rheumatoid arthritis
0.945 0.055 0.000
I05 Rheumatic mitral valve diseases
0.945 0.055 0.000
M22.4 Chondromalacia patellae
0.945 0.055 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.944 0.056 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.944 0.056 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.944 0.056 0.000
M25.46 Effusion of joint (Lower leg)
0.944 0.056 0.000
G93.0 Cerebral cysts
0.944 0.056 0.000
G93.2 Benign intracranial hypertension
0.943 0.057 0.000
H57 Other disorders of eye and adnexa
0.943 0.057 0.000
S01.3 Open wound of ear
0.943 0.057 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.943 0.057 0.000
N99-N99 Other disorders of the genitourinary system
0.942 0.058 0.000
Z89 Acquired absence of limb
0.942 0.058 0.000
I80 Phlebitis and thrombophlebitis
0.942 0.058 0.000
S22.40 Multiple fractures of ribs (closed)
0.942 0.058 0.000
S05.8 Other injuries of eye and orbit
0.941 0.059 0.000
T87 Complications peculiar to reattachment and amputation
0.941 0.059 0.000
E29 Testicular dysfunction
0.941 0.059 0.000
O80-O84 Delivery
0.941 0.059 0.000
S89.9 Unspecified injury of lower leg
0.940 0.060 0.000
M85 Other disorders of bone density and structure
0.940 0.060 0.000
H18 Other disorders of cornea
0.939 0.061 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.938 0.062 0.000
M25.37 Other instability of joint (Ankle and foot)
0.938 0.062 0.000
R47.1 Dysarthria and anarthria
0.938 0.062 0.000
G30.9 Alzheimer's disease, unspecified
0.938 0.062 0.000
K86 Other diseases of pancreas
0.938 0.062 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.936 0.064 0.000
W18.3 Sports and athletics area
0.936 0.064 0.000
C18.6 Descending colon
0.936 0.064 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.936 0.064 0.000
I44 Atrioventricular and left bundle-branch block
0.936 0.064 0.000
B25-B34 Other viral diseases
0.936 0.064 0.000
Z93.0 Tracheostomy status
0.935 0.065 0.000
M80 Osteoporosis with pathological fracture
0.935 0.065 0.000
R82 Other abnormal findings in urine
0.935 0.065 0.000
C80 Malignant neoplasm without specification of site
0.934 0.066 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.934 0.066 0.000
A80-A89 Viral infections of the central nervous system
0.934 0.066 0.000
L60.0 Ingrowing nail
0.934 0.066 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.934 0.066 0.000
I33 Acute and subacute endocarditis
0.934 0.066 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.934 0.066 0.000
H66.3 Other chronic suppurative otitis media
0.934 0.066 0.000
K11 Diseases of salivary glands
0.933 0.067 0.000
G03 Meningitis due to other and unspecified causes
0.933 0.067 0.000
M19 Other arthrosis
0.932 0.068 0.000
I45.9 Conduction disorder, unspecified
0.932 0.068 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.932 0.068 0.000
I74 Arterial embolism and thrombosis
0.932 0.068 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.932 0.068 0.000
S30.1 Contusion of abdominal wall
0.932 0.068 0.000
I49.8 Other specified cardiac arrhythmias
0.931 0.069 0.000
I49.1 Atrial premature depolarisation
0.931 0.069 0.000
T93 Sequelae of injuries of lower limb
0.931 0.069 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.931 0.069 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.930 0.070 0.000
H26.2 Complicated cataract
0.930 0.070 0.000
H61 Other disorders of external ear
0.930 0.070 0.000
H26.0 Infantile, juvenile and presenile cataract
0.930 0.070 0.000
R44.0 Auditory hallucinations
0.930 0.070 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.930 0.070 0.000
G12.2 Motor neuron disease
0.930 0.070 0.000
K05 Gingivitis and periodontal diseases
0.928 0.072 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.928 0.072 0.000
G96 Other disorders of central nervous system
0.928 0.072 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.928 0.072 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.927 0.073 0.000
J95-J99 Other diseases of the respiratory system
0.927 0.073 0.000
S51.0 Open wound of elbow
0.927 0.073 0.000
B65-B83 Helminthiases
0.926 0.074 0.000
H27 Other disorders of lens
0.926 0.074 0.000
N76.2 Acute vulvitis
0.926 0.074 0.000
G91.1 Obstructive hydrocephalus
0.926 0.074 0.000
I72.4 Aneurysm of artery of lower extremity
0.926 0.074 0.000
S27.2 Traumatic heamopneumothorax
0.925 0.075 0.000
H11.0 Pterygium
0.925 0.075 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.925 0.075 0.000
M54.50 Low back pain (Multiple sites in spine)
0.924 0.076 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.924 0.076 0.000
A40.8 Other streptococcal septicaemia
0.924 0.076 0.000
M25.9 Joint disorder, unspecified
0.923 0.077 0.000
D03.5 Melanoma in situ of trunk
0.923 0.077 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.923 0.077 0.000
T90 Sequelae of injuries of head
0.922 0.078 0.000
M24.2 Disorder of ligament
0.922 0.078 0.000
J90-J94 Other diseases of pleura
0.922 0.078 0.000
E28.2 Polycystic ovarian syndrome
0.922 0.078 0.000
E23 Hypofunction and other disorders of pituitary gland
0.922 0.078 0.000
C32 Malignant neoplasm of larynx
0.922 0.078 0.000
I44.2 Atrioventricular block, complete
0.922 0.078 0.000
J69 Pneumonitis due to solids and liquids
0.921 0.079 0.000
H11.3 Conjunctival haemorrhage
0.921 0.079 0.000
H10.9 Conjunctivitis, unspecified
0.921 0.079 0.000
I71.0 Dissection of aorta [any part]
0.921 0.079 0.000
C01 Malignant neoplasm of base of tongue
0.921 0.079 0.000
H47.3 Other disorders of optic disk
0.921 0.079 0.000
K12.3 Oral mucositis (ulcerative)
0.921 0.079 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.921 0.079 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.920 0.080 0.000
O66 Other obstructed labour
0.920 0.080 0.000
M51.8 Other specified intervertebral disk disorders
0.920 0.080 0.000
M66 Spontaneous rupture of synovium and tendon
0.919 0.081 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.919 0.081 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.919 0.081 0.000
M16.7 Other secondary coxarthrosis
0.919 0.081 0.000
I87.1 Compression of vein
0.919 0.081 0.000
M71 Other bursopathies
0.919 0.081 0.000
I08.8 Other multiple valve diseases
0.919 0.081 0.000
H16 Keratitis
0.919 0.081 0.000
M79.1 Myalgia
0.918 0.082 0.000
O82 Single delivery by Caesarean section
0.918 0.082 0.000
S06.0 Concussion
0.918 0.082 0.000
Q00-Q07 Congenital malformations of the nervous system
0.918 0.082 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.918 0.082 0.000
Z52.4 Kidney donor
0.918 0.082 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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