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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117825839
log Bayes Factor = 16.5381
Chromosome 12   position 28,978,196  (GRCh37) Explore rs117825839 on Ensembl!
Variant rs117825839 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
R50-R69 General symptoms and signs
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
R50 Fever of unknown origin
0.998 0.002 0.000
R55 Syncope and collapse
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.997 0.003 0.000
Chapter VIII Diseases of the ear and mastoid process
0.997 0.003 0.000
R51 Headache
0.997 0.003 0.000
I20 Angina pectoris
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
R50.9 Fever, unspecified
0.992 0.008 0.000
I20.0 Unstable angina
0.991 0.009 0.000
R07 Pain in throat and chest
0.991 0.009 0.000
R07.2 Precordial pain
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
I34 Nonrheumatic mitral valve disorders
0.983 0.017 0.000
R06 Abnormalities of breathing
0.981 0.019 0.000
I50 Heart failure
0.978 0.022 0.000
I44 Atrioventricular and left bundle-branch block
0.977 0.023 0.000
M20-M25 Other joint disorders
0.971 0.029 0.000
D60-D64 Aplastic and other anaemias
0.966 0.034 0.000
R06.0 Dyspnoea
0.960 0.040 0.000
D64 Other anaemias
0.955 0.045 0.000
I34.0 Mitral (valve) insufficiency
0.954 0.046 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.954 0.046 0.000
H65-H75 Diseases of middle ear and mastoid
0.952 0.048 0.000
I60-I69 Cerebrovascular diseases
0.949 0.051 0.000
I45 Other conduction disorders
0.948 0.052 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.948 0.052 0.000
D64.9 Anaemia, unspecified
0.948 0.052 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.947 0.053 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.943 0.057 0.000
M70-M79 Other soft tissue disorders
0.937 0.063 0.000
M23 Internal derangement of knee
0.935 0.065 0.000
H90-H95 Other disorders of ear
0.933 0.067 0.000
I50.1 Left ventricular failure
0.933 0.067 0.000
Chapter XX External causes of morbidity and mortality
0.918 0.082 0.000
O20 Haemorrhage in early pregnancy
0.916 0.084 0.000
H65 Nonsuppurative otitis media
0.912 0.088 0.000
H80-H83 Diseases of inner ear
0.911 0.088 0.000
R50.8 Other specified fever
0.911 0.089 0.000
O00-O08 Pregnancy with abortive outcome
0.899 0.101 0.000
O47 False labour
0.897 0.103 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.897 0.103 0.000
D80-D89 Certain disorders involving the immune mechanism
0.892 0.108 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.891 0.109 0.000
I63 Cerebral infarction
0.888 0.112 0.000
I49 Other cardiac arrhythmias
0.887 0.113 0.000
H65.3 Chronic mucoid otitis media
0.887 0.113 0.000
I45.1 Other and unspecified right bundle-branch block
0.880 0.120 0.000
R00 Abnormalities of heart beat
0.879 0.121 0.000
M22 Disorders of patella
0.878 0.122 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.878 0.122 0.000
I25 Chronic ischaemic heart disease
0.870 0.130 0.000
H91 Other hearing loss
0.870 0.130 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.869 0.131 0.000
M65-M68 Disorders of synovium and tendon
0.867 0.133 0.000
I44.2 Atrioventricular block, complete
0.867 0.133 0.000
I34.1 Mitral (valve) prolapse
0.864 0.136 0.000
R03.1 Nonspecific low blood-pressure reading
0.861 0.139 0.000
I50.9 Heart failure, unspecified
0.859 0.141 0.000
O20.0 Threatened abortion
0.858 0.142 0.000
I05-I09 Chronic rheumatic heart diseases
0.857 0.143 0.000
H66 Suppurative and unspecified otitis media
0.854 0.146 0.000
I44.0 Atrioventricular block, first degree
0.850 0.150 0.000
I44.7 Left bundle-branch block, unspecified
0.843 0.157 0.000
I63.9 Cerebral infarction, unspecified
0.842 0.158 0.000
D50-D53 Nutritional anaemias
0.838 0.162 0.000
H80 Otosclerosis
0.834 0.166 0.000
R07.3 Other chest pain
0.833 0.167 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.831 0.169 0.000
I35 Nonrheumatic aortic valve disorders
0.831 0.169 0.000
R73 Elevated blood glucose level
0.830 0.170 0.000
R68 Other general symptoms and signs
0.829 0.171 0.000
R02 Gangrene, not elsewhere classified
0.829 0.171 0.000
M72 Fibroblastic disorders
0.829 0.171 0.000
S60-S69 Injuries to the wrist and hand
0.828 0.172 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.827 0.173 0.000
R79 Other abnormal findings of blood chemistry
0.827 0.173 0.000
H91.9 Hearing loss, unspecified
0.825 0.175 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.821 0.179 0.000
I67 Other cerebrovascular diseases
0.821 0.179 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.820 0.180 0.000
H92 Otalgia and effusion of ear
0.819 0.181 0.000
O47.9 False labour, unspecified
0.818 0.182 0.000
R53 Malaise and fatigue
0.817 0.183 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.816 0.184 0.000
O02 Other abnormal products of conception
0.816 0.184 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.815 0.185 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.813 0.187 0.000
R54 Senility
0.812 0.188 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.811 0.189 0.000
I20.8 Other forms of angina pectoris
0.810 0.190 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.807 0.193 0.000
M23.8 Other internal derangements of knee
0.807 0.193 0.000
M23.5 Chronic instability of knee
0.806 0.194 0.000
Y43 Primarily systemic agents
0.806 0.194 0.000
O42 Premature rupture of membranes
0.806 0.194 0.000
I45.6 Preexcitation syndrome
0.802 0.198 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.801 0.199 0.000
M75 Shoulder lesions
0.800 0.200 0.000
R57 Shock, not elsewhere classified
0.800 0.200 0.000
I44.1 Atrioventricular block, second degree
0.796 0.204 0.000
M31 Other necrotising vasculopathies
0.795 0.205 0.000
O80-O84 Delivery
0.791 0.209 0.000
I62 Other nontraumatic intracranial haemorrhage
0.790 0.210 0.000
R06.6 Hiccough
0.786 0.214 0.000
D86 Sarcoidosis
0.784 0.216 0.000
H81 Disorders of vestibular function
0.784 0.216 0.000
M22.4 Chondromalacia patellae
0.782 0.218 0.000
H60-H62 Diseases of external ear
0.781 0.219 0.000
H80.9 Otosclerosis, unspecified
0.779 0.221 0.000
R76 Other abnormal immunological findings in serum
0.779 0.221 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.775 0.225 0.000
I24 Other acute ischaemic heart diseases
0.774 0.226 0.000
O41 Other disorders of amniotic fluid and membranes
0.773 0.227 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.769 0.231 0.000
R73.9 Hyperglycaemia, unspecified
0.768 0.232 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.766 0.234 0.000
H66.9 Otitis media, unspecified
0.765 0.235 0.000
R58 Haemorrhage, not elsewhere classified
0.764 0.236 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.763 0.237 0.000
I08 Multiple valve diseases
0.761 0.239 0.000
R00.2 Palpitations
0.759 0.241 0.000
M21 Other acquired deformities of limbs
0.759 0.241 0.000
I50.0 Congestive heart failure
0.756 0.244 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.755 0.245 0.000
Y43.3 Other antineoplastic drugs
0.755 0.245 0.000
I49.0 Ventricular fibrillation and flutter
0.754 0.246 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.754 0.246 0.000
I42 Cardiomyopathy
0.753 0.247 0.000
O43 Placental disorders
0.752 0.248 0.000
I22 Subsequent myocardial infarction
0.751 0.249 0.000
R47-R49 Symptoms and signs involving speech and voice
0.749 0.251 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.749 0.251 0.000
R06.2 Wheezing
0.747 0.252 0.000
I20.1 Angina pectoris with documented spasm
0.747 0.253 0.000
T66-T78 Other and unspecified effects of external causes
0.744 0.256 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.742 0.258 0.000
R01 Cardiac murmurs and other cardiac sounds
0.742 0.258 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.741 0.259 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.739 0.261 0.000
R50.0 Fever with chills
0.738 0.262 0.000
D55-D59 Haemolytic anaemias
0.735 0.265 0.000
I51 Complications and ill-defined descriptions of heart disease
0.735 0.265 0.000
D50 Iron deficiency anaemia
0.733 0.267 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.731 0.269 0.000
S65 Injury of blood vessels at wrist and hand level
0.730 0.270 0.000
M24 Other specific joint derangements
0.730 0.270 0.000
O36 Maternal care for other known or suspected foetal problems
0.729 0.271 0.000
M67 Other disorders of synovium and tendon
0.729 0.271 0.000
I20.9 Angina pectoris, unspecified
0.728 0.272 0.000
R26 Abnormalities of gait and mobility
0.728 0.272 0.000
I67.9 Cerebrovascular disease, unspecified
0.727 0.273 0.000
M91-M94 Chondropathies
0.726 0.274 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.726 0.274 0.000
M05-M14 Inflammatory polyarthropathies
0.725 0.275 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.722 0.278 0.000
Y44 Agents primarily affecting blood constituents
0.721 0.279 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.720 0.280 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.720 0.280 0.000
I31 Other diseases of pericardium
0.719 0.281 0.000
M65 Synovitis and tenosynovitis
0.719 0.281 0.000
O00 Ectopic pregnancy
0.719 0.281 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
Chapter II Neoplasms
0.716 0.284 0.000
R50.2 Drug-induced fever
0.715 0.285 0.000
R50.1 Persistent fever
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.714 0.286 0.000
I30 Acute pericarditis
0.713 0.287 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.713 0.287 0.000
R59 Enlarged lymph nodes
0.712 0.288 0.000
H74 Other disorders of middle ear and mastoid
0.712 0.288 0.000
M25 Other joint disorders, not elsewhere classified
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
R60 Oedema, not elsewhere classified
0.711 0.289 0.000
M86-M90 Other osteopathies
0.709 0.291 0.000
I49.9 Cardiac arrhythmia, unspecified
0.709 0.291 0.000
M35 Other systemic involvement of connective tissue
0.709 0.291 0.000
R06.8 Other and unspecified abnormalities of breathing
0.708 0.292 0.000
M22.2 Patellofemoral disorders
0.707 0.293 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.706 0.294 0.000
H81.1 Benign paroxysmal vertigo
0.706 0.294 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.705 0.295 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.705 0.295 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.705 0.295 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.705 0.295 0.000
H71 Cholesteatoma of middle ear
0.704 0.295 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.704 0.296 0.000
R06.7 Sneezing
0.703 0.296 0.000
R06.3 Periodic breathing
0.703 0.296 0.000
R06.1 Stridor
0.703 0.296 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.703 0.296 0.000
R06.4 Hyperventilation
0.703 0.297 0.000
R25 Abnormal involuntary movements
0.701 0.299 0.000
I44.6 Other and unspecified fascicular block
0.701 0.299 0.000
I44.5 Left posterior fascicular block
0.701 0.299 0.000
I44.4 Left anterior fascicular block
0.701 0.299 0.000
I44.3 Other and unspecified atrioventricular block
0.701 0.299 0.000
I38 Endocarditis, valve unspecified
0.700 0.300 0.000
V40-V49 Car occupant injured in transport accident
0.700 0.300 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
Chapter V Mental and behavioural disorders
0.699 0.301 0.000
I49.3 Ventricular premature depolarisation
0.699 0.301 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.698 0.302 0.000
I25.5 Ischaemic cardiomyopathy
0.698 0.302 0.000
M75.0 Adhesive capsulitis of shoulder
0.698 0.302 0.000
O82 Single delivery by Caesarean section
0.697 0.303 0.000
M71 Other bursopathies
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M34 Systemic sclerosis
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
S64 Injury of nerves at wrist and hand level
0.696 0.304 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.695 0.305 0.000
H92.0 Otalgia
0.693 0.307 0.000
R05 Cough
0.693 0.307 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.692 0.307 0.000
R07.0 Pain in throat
0.692 0.308 0.000
H65.4 Other chronic nonsuppurative otitis media
0.692 0.308 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.691 0.309 0.000
S90-S99 Injuries to the ankle and foot
0.690 0.309 0.000
D64.8 Other specified anaemias
0.685 0.315 0.000
D64.4 Congenital dyserythropoietic anaemia
0.685 0.315 0.000
D64.3 Other sideroblastic anaemias
0.685 0.315 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.685 0.315 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.685 0.315 0.000
D64.0 Hereditary sideroblastic anaemia
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.684 0.316 0.000
O45 Premature separation of placenta [abruptio placentae]
0.684 0.316 0.000
O44 Placenta praevia
0.684 0.316 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.684 0.316 0.000
O33 Maternal care for known or suspected disproportion
0.684 0.316 0.000
O31 Complications specific to multiple gestation
0.684 0.316 0.000
O40 Polyhydramnios
0.684 0.316 0.000
R80 Isolated proteinuria
0.683 0.317 0.000
I60 Subarachnoid haemorrhage
0.683 0.317 0.000
R06.5 Mouth breathing
0.683 0.317 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.682 0.318 0.000
H70 Mastoiditis and related conditions
0.682 0.318 0.000
H69 Other disorders of Eustachian tube
0.682 0.318 0.000
H68 Eustachian salpingitis and obstruction
0.682 0.318 0.000
H67 Otitis media in diseases classified elsewhere
0.682 0.318 0.000
I69 Sequelae of cerebrovascular disease
0.682 0.318 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.680 0.320 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.680 0.320 0.000
I45.9 Conduction disorder, unspecified
0.680 0.320 0.000
I45.8 Other specified conduction disorders
0.680 0.320 0.000
I45.5 Other specified heart block
0.680 0.320 0.000
I45.4 Nonspecific intraventricular block
0.680 0.320 0.000
I45.3 Trifascicular block
0.680 0.320 0.000
I45.2 Bifascicular block
0.680 0.320 0.000
I45.0 Right fascicular block
0.680 0.320 0.000
O29 Complications of anaesthesia during pregnancy
0.679 0.320 0.000
O28 Abnormal findings on antenatal screening of mother
0.679 0.320 0.000
O24 Diabetes mellitus in pregnancy
0.679 0.320 0.000
O23 Infections of genito-urinary tract in pregnancy
0.679 0.320 0.000
O22 Venous complications in pregnancy
0.679 0.320 0.000
O21 Excessive vomiting in pregnancy
0.679 0.320 0.000
O25 Malnutrition in pregnancy
0.679 0.320 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.679 0.321 0.000
R77 Other abnormalities of plasma proteins
0.679 0.321 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.679 0.321 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.679 0.321 0.000
R71 Abnormality of red blood cells
0.679 0.321 0.000
M75.5 Bursitis of shoulder
0.678 0.322 0.000
I49.4 Other and unspecified premature depolarisation
0.677 0.323 0.000
D68 Other coagulation defects
0.676 0.324 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.675 0.325 0.000
Chapter VII Diseases of the eye and adnexa
0.675 0.325 0.000
O04 Medical abortion
0.675 0.325 0.000
V80-V89 Other land transport accidents
0.673 0.327 0.000
M76 Enthesopathies of lower limb, excluding foot
0.671 0.328 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.671 0.328 0.000
S61 Open wound of wrist and hand
0.671 0.329 0.000
H92.1 Otorrhoea
0.670 0.329 0.000
M23.9 Internal derangement of knee, unspecified
0.670 0.330 0.000
M23.1 Discoid meniscus (congenital)
0.670 0.330 0.000
M23.0 Cystic meniscus
0.670 0.330 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.670 0.330 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.330 0.000
S10-S19 Injuries to the neck
0.670 0.330 0.000
R40 Somnolence, stupor and coma
0.670 0.330 0.000
Y52 Agents primarily affecting the cardiovascular system
0.669 0.331 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.669 0.331 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.669 0.331 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.669 0.331 0.000
M31.6 Other giant cell arteritis
0.668 0.332 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.668 0.332 0.000
M77 Other enthesopathies
0.668 0.332 0.000
O42.9 Premature rupture of membranes, unspecified
0.667 0.332 0.000
M80-M85 Disorders of bone density and structure
0.667 0.332 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.666 0.334 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.665 0.335 0.000
H66.3 Other chronic suppurative otitis media
0.664 0.336 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.664 0.336 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.663 0.337 0.000
S20-S29 Injuries to the thorax
0.663 0.337 0.000
I33 Acute and subacute endocarditis
0.662 0.338 0.000
R74 Abnormal serum enzyme levels
0.662 0.338 0.000
M40-M43 Deforming dorsopathies
0.662 0.338 0.000
D86.0 Sarcoidosis of lung
0.660 0.340 0.000
R00.1 Bradycardia, unspecified
0.660 0.340 0.000
R76.8 Other specified abnormal immunological findings in serum
0.659 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.658 0.342 0.000
Y35-Y36 Legal intervention and operations of war
0.658 0.342 0.000
Y10-Y34 Event of undetermined intent
0.658 0.342 0.000
Y00-Y09 Assault
0.658 0.342 0.000
X85-X99 Assault
0.658 0.342 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.658 0.342 0.000
X50-X57 Overexertion, travel and privation
0.658 0.342 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.342 0.000
X30-X39 Exposure to forces of nature
0.658 0.342 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.342 0.000
X10-X19 Contact with heat and hot substances
0.658 0.342 0.000
X00-X09 Exposure to smoke, fire and flames
0.658 0.342 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.658 0.342 0.000
W75-W84 Other accidental threats to breathing
0.658 0.342 0.000
W65-W74 Accidental drowning and submersion
0.658 0.342 0.000
W50-W64 Exposure to animate mechanical forces
0.658 0.342 0.000
V98-V99 Other and unspecified transport accidents
0.658 0.342 0.000
V95-V97 Air and space transport accidents
0.658 0.342 0.000
V90-V94 Water transport accidents
0.658 0.342 0.000
V70-V79 Bus occupant injured in transport accident
0.658 0.342 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.658 0.342 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.658 0.342 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.658 0.342 0.000
V01-V09 Pedestrian injured in transport accident
0.658 0.342 0.000
I25.3 Aneurysm of heart
0.658 0.342 0.000
O20.8 Other haemorrhage in early pregnancy
0.657 0.343 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.656 0.344 0.000
R07.1 Chest pain on breathing
0.655 0.344 0.000
O02.1 Missed abortion
0.654 0.346 0.000
H65.2 Chronic serous otitis media
0.654 0.346 0.000
H65.1 Other acute nonsuppurative otitis media
0.654 0.346 0.000
H65.0 Acute serous otitis media
0.654 0.346 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.653 0.346 0.000
R68.8 Other specified general symptoms and signs
0.653 0.347 0.000
R04 Haemorrhage from respiratory passages
0.653 0.347 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.652 0.348 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.652 0.348 0.000
I21 Acute myocardial infarction
0.651 0.349 0.000
D50.8 Other iron deficiency anaemias
0.651 0.349 0.000
T90 Sequelae of injuries of head
0.651 0.349 0.000
C60-C63 Malignant neoplasms of male genital organs
0.650 0.350 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.650 0.350 0.000
O30 Multiple gestation
0.650 0.350 0.000
I51.9 Heart disease, unspecified
0.649 0.351 0.000
O47.0 False labour before 37 completed weeks of gestation
0.648 0.352 0.000
D86.9 Sarcoidosis, unspecified
0.647 0.353 0.000
Q00-Q07 Congenital malformations of the nervous system
0.647 0.353 0.000
I05 Rheumatic mitral valve diseases
0.647 0.353 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.646 0.354 0.000
V20-V29 Motorcycle rider injured in transport accident
0.645 0.355 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.645 0.355 0.000
O07 Failed attempted abortion
0.645 0.355 0.000
O06 Unspecified abortion
0.645 0.355 0.000
O05 Other abortion
0.645 0.355 0.000
O01 Hydatidiform mole
0.645 0.355 0.000
O41.0 Oligohydramnios
0.644 0.356 0.000
T33-T35 Frostbite
0.643 0.357 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.643 0.357 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.643 0.357 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.643 0.357 0.000
T00-T07 Injuries involving multiple body regions
0.643 0.357 0.000
D52 Folate deficiency anaemia
0.642 0.357 0.000
Chapter I Certain infectious and parasitic diseases
0.642 0.358 0.000
I25.2 Old myocardial infarction
0.641 0.359 0.000
D84 Other immunodeficiencies
0.639 0.361 0.000
D83 Common variable immunodeficiency
0.639 0.361 0.000
D82 Immunodeficiency associated with other major defects
0.639 0.361 0.000
D81 Combined immunodeficiencies
0.639 0.361 0.000
D80 Immunodeficiency with predominantly antibody defects
0.639 0.361 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.639 0.361 0.000
O97 Death from sequelae of direct obstetric causes
0.639 0.361 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.639 0.361 0.000
O95 Obstetric death of unspecified cause
0.639 0.361 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.639 0.361 0.000
I35.0 Aortic (valve) stenosis
0.639 0.361 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.639 0.361 0.000
I67.1 Cerebral aneurysm, nonruptured
0.639 0.361 0.000
R57.0 Cardiogenic shock
0.638 0.362 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.638 0.362 0.000
M25.7 Osteophyte
0.637 0.363 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.637 0.363 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.637 0.363 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.637 0.363 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.637 0.363 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.637 0.363 0.000
H93 Other disorders of ear, not elsewhere classified
0.637 0.363 0.000
W20-W49 Exposure to inanimate mechanical forces
0.636 0.364 0.000
I49.2 Junctional premature depolarisation
0.636 0.364 0.000
I49.1 Atrial premature depolarisation
0.636 0.364 0.000
I49.5 Sick sinus syndrome
0.636 0.364 0.000
I61 Intracerebral haemorrhage
0.635 0.365 0.000
T78 Adverse effects, not elsewhere classified
0.634 0.365 0.000
I35.1 Aortic (valve) insufficiency
0.634 0.366 0.000
S60 Superficial injury of wrist and hand
0.632 0.368 0.000
I24.8 Other forms of acute ischaemic heart disease
0.631 0.369 0.000
Chapter XXII Codes for special purposes
0.630 0.370 0.000
M67.8 Other specified disorders of synovium and tendon
0.630 0.370 0.000
I46 Cardiac arrest
0.630 0.370 0.000
D61 Other aplastic anaemias
0.630 0.370 0.000
M22.1 Recurrent subluxation of patella
0.630 0.370 0.000
M22.9 Disorder of patella, unspecified
0.630 0.370 0.000
M22.8 Other disorders of patella
0.630 0.370 0.000
M22.3 Other derangements of patella
0.630 0.370 0.000
M22.0 Recurrent dislocation of patella
0.630 0.370 0.000
Y59 Other and unspecified vaccines and biological substances
0.630 0.370 0.000
Y58 Bacterial vaccines
0.630 0.370 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.630 0.370 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.630 0.370 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.630 0.370 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.630 0.370 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.630 0.370 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.630 0.370 0.000
Y48 Anaesthetics and therapeutic gases
0.630 0.370 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.630 0.370 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.630 0.370 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.630 0.370 0.000
S70-S79 Injuries to the hip and thigh
0.627 0.373 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.626 0.374 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.626 0.374 0.000
R25.2 Cramp and spasm
0.626 0.374 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.625 0.375 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.625 0.375 0.000
I25.6 Silent myocardial ischaemia
0.624 0.376 0.000
I25.4 Coronary artery aneurysm
0.624 0.376 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.624 0.376 0.000
H91.8 Other specified hearing loss
0.624 0.376 0.000
H91.3 Deaf mutism, not elsewhere classified
0.624 0.376 0.000
H91.2 Sudden idiopathic hearing loss
0.624 0.376 0.000
H91.1 Presbycusis
0.624 0.376 0.000
H91.0 Ototoxic hearing loss
0.624 0.376 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.623 0.377 0.000
M75.3 Calcific tendinitis of shoulder
0.622 0.378 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.622 0.378 0.000
M66 Spontaneous rupture of synovium and tendon
0.622 0.378 0.000
I67.2 Cerebral atherosclerosis
0.621 0.378 0.000
M75.4 Impingement syndrome of shoulder
0.621 0.379 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.621 0.379 0.000
C62 Malignant neoplasm of testis
0.620 0.380 0.000
H61 Other disorders of external ear
0.619 0.381 0.000
D50.9 Iron deficiency anaemia, unspecified
0.619 0.381 0.000
M79.7 Fibromyalgia
0.618 0.382 0.000
M79.6 Pain in limb
0.618 0.382 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.618 0.382 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.618 0.382 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.618 0.382 0.000
T79-T79 Certain early complications of trauma
0.617 0.383 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.617 0.383 0.000
V10-V19 Pedal cyclist injured in transport accident
0.615 0.385 0.000
I09 Other rheumatic heart diseases
0.615 0.385 0.000
I06 Rheumatic aortic valve diseases
0.615 0.385 0.000
R52 Pain, not elsewhere classified
0.614 0.386 0.000
M79.0 Rheumatism, unspecified
0.614 0.386 0.000
S50-S59 Injuries to the elbow and forearm
0.614 0.386 0.000
R42 Dizziness and giddiness
0.613 0.386 0.000
D62 Acute posthaemorrhagic anaemia
0.613 0.387 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.613 0.387 0.000
H66.4 Suppurative otitis media, unspecified
0.612 0.388 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.612 0.388 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.612 0.388 0.000
H66.0 Acute suppurative otitis media
0.612 0.388 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.609 0.391 0.000
Y44.2 Anticoagulants
0.608 0.391 0.000
O43.8 Other placental disorders
0.608 0.392 0.000
R59.1 Generalised enlarged lymph nodes
0.607 0.393 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.606 0.394 0.000
R79.0 Abnormal level of blood mineral
0.606 0.394 0.000
Q80-Q89 Other congenital malformations
0.606 0.394 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.605 0.394 0.000
R45 Symptoms and signs involving emotional state
0.605 0.395 0.000
X60-X84 Intentional self-harm
0.605 0.395 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.605 0.395 0.000
M72.2 Plantar fascial fibromatosis
0.604 0.396 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.604 0.396 0.000
B25-B34 Other viral diseases
0.604 0.396 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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