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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78586881
log Bayes Factor = 15.3006
Chromosome 8   position 37,144,739  (GRCh37) Explore rs78586881 on Ensembl!
Variant rs78586881 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.994 0.006 0.000
M54 Dorsalgia
0.994 0.006 0.000
R53 Malaise and fatigue
0.992 0.008 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.990 0.010 0.000
R20 Disturbances of skin sensation
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
R06 Abnormalities of breathing
0.983 0.017 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.982 0.018 0.000
H53-H54 Visual disturbances and blindness
0.979 0.021 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.978 0.022 0.000
I20-I25 Ischaemic heart diseases
0.976 0.024 0.000
R06.5 Mouth breathing
0.972 0.028 0.000
M54.9 Dorsalgia, unspecified
0.970 0.030 0.000
M54.5 Low back pain
0.969 0.031 0.000
M20-M25 Other joint disorders
0.967 0.033 0.000
M45-M49 Spondylopathies
0.967 0.033 0.000
I60-I69 Cerebrovascular diseases
0.965 0.035 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.963 0.037 0.000
I67 Other cerebrovascular diseases
0.956 0.044 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.955 0.045 0.000
R63 Symptoms and signs concerning food and fluid intake
0.954 0.046 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.954 0.046 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.953 0.047 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.951 0.049 0.000
Chapter X Diseases of the respiratory system
0.950 0.050 0.000
M47 Spondylosis
0.949 0.051 0.000
R54 Senility
0.949 0.051 0.000
R56 Convulsions, not elsewhere classified
0.946 0.054 0.000
I67.9 Cerebrovascular disease, unspecified
0.943 0.057 0.000
M70-M79 Other soft tissue disorders
0.943 0.057 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.942 0.058 0.000
Y43 Primarily systemic agents
0.936 0.064 0.000
F30-F39 Mood [affective] disorders
0.935 0.065 0.000
R00 Abnormalities of heart beat
0.931 0.069 0.000
I21 Acute myocardial infarction
0.930 0.070 0.000
S20-S29 Injuries to the thorax
0.929 0.071 0.000
H30-H36 Disorders of choroid and retina
0.928 0.072 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.919 0.081 0.000
H53 Visual disturbances
0.917 0.083 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.917 0.083 0.000
H54 Blindness and low vision
0.917 0.083 0.000
Chapter II Neoplasms
0.911 0.089 0.000
R56.8 Other and unspecified convulsions
0.908 0.092 0.000
F10.2 Dependence syndrome
0.906 0.094 0.000
R20.2 Paraesthesia of skin
0.903 0.097 0.000
J20-J22 Other acute lower respiratory infections
0.902 0.098 0.000
R00.2 Palpitations
0.901 0.099 0.000
M77 Other enthesopathies
0.900 0.100 0.000
M47.9 Spondylosis, unspecified
0.899 0.101 0.000
M54.56 Low back pain (Lumbar region)
0.898 0.102 0.000
Y43.3 Other antineoplastic drugs
0.893 0.107 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.889 0.111 0.000
M86-M90 Other osteopathies
0.888 0.112 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.886 0.114 0.000
H43-H45 Disorders of vitreous body and globe
0.884 0.116 0.000
R63.0 Anorexia
0.875 0.125 0.000
M22 Disorders of patella
0.874 0.126 0.000
I22 Subsequent myocardial infarction
0.871 0.129 0.000
H33 Retinal detachments and breaks
0.871 0.129 0.000
F31 Bipolar affective disorder
0.870 0.130 0.000
R06.2 Wheezing
0.869 0.131 0.000
J22 Unspecified acute lower respiratory infection
0.868 0.132 0.000
F10.3 Withdrawal state
0.867 0.133 0.000
H53.2 Diplopia
0.867 0.133 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.865 0.135 0.000
M25 Other joint disorders, not elsewhere classified
0.864 0.136 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.863 0.137 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.858 0.142 0.000
M65-M68 Disorders of synovium and tendon
0.857 0.143 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.853 0.147 0.000
I26 Pulmonary embolism
0.851 0.149 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.850 0.150 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.850 0.150 0.000
D00-D09 In situ neoplasms
0.846 0.154 0.000
M24 Other specific joint derangements
0.845 0.155 0.000
I67.2 Cerebral atherosclerosis
0.844 0.156 0.000
M54.57 Low back pain (Lumbosacral region)
0.843 0.157 0.000
M23 Internal derangement of knee
0.842 0.158 0.000
J90-J94 Other diseases of pleura
0.842 0.158 0.000
J00-J06 Acute upper respiratory infections
0.841 0.159 0.000
I20 Angina pectoris
0.839 0.161 0.000
J09-J18 Influenza and pneumonia
0.837 0.163 0.000
M47.8 Other spondylosis
0.834 0.166 0.000
M54.59 Low back pain (Site unspecified)
0.831 0.169 0.000
S27 Injury of other and unspecified intrathoracic organs
0.830 0.170 0.000
M51 Other intervertebral disk disorders
0.828 0.172 0.000
R59 Enlarged lymph nodes
0.828 0.172 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.827 0.173 0.000
R41.0 Disorientation, unspecified
0.824 0.176 0.000
H55-H59 Other disorders of eye and adnexa
0.824 0.176 0.000
I27 Other pulmonary heart diseases
0.823 0.177 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.821 0.179 0.000
M21 Other acquired deformities of limbs
0.820 0.180 0.000
S80-S89 Injuries to the knee and lower leg
0.820 0.180 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.819 0.181 0.000
C60-C63 Malignant neoplasms of male genital organs
0.819 0.181 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.818 0.182 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.816 0.184 0.000
S22.3 Fracture of rib
0.814 0.186 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.814 0.186 0.000
W00-W19 Falls
0.813 0.186 0.000
H10-H13 Disorders of conjunctiva
0.812 0.188 0.000
M80-M85 Disorders of bone density and structure
0.811 0.189 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.810 0.190 0.000
R57 Shock, not elsewhere classified
0.807 0.193 0.000
M89 Other disorders of bone
0.807 0.193 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.806 0.194 0.000
I05-I09 Chronic rheumatic heart diseases
0.801 0.199 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.801 0.199 0.000
R58 Haemorrhage, not elsewhere classified
0.800 0.200 0.000
R44.1 Visual hallucinations
0.799 0.200 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.799 0.201 0.000
I77 Other disorders of arteries and arterioles
0.799 0.201 0.000
R06.6 Hiccough
0.797 0.203 0.000
R02 Gangrene, not elsewhere classified
0.795 0.205 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.792 0.208 0.000
V10-V19 Pedal cyclist injured in transport accident
0.792 0.208 0.000
I63 Cerebral infarction
0.792 0.208 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.788 0.212 0.000
H54.4 Blindness, one eye
0.788 0.212 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.787 0.213 0.000
M22.2 Patellofemoral disorders
0.786 0.214 0.000
R60 Oedema, not elsewhere classified
0.785 0.214 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.785 0.215 0.000
H25-H28 Disorders of lens
0.785 0.215 0.000
M54.4 Lumbago with sciatica
0.785 0.215 0.000
H54.7 Unspecified visual loss
0.782 0.218 0.000
H43 Disorders of vitreous body
0.781 0.219 0.000
F11 Mental and behavioural disorders due to use of opioids
0.780 0.220 0.000
S22.30 Fracture of rib (closed)
0.778 0.222 0.000
R01 Cardiac murmurs and other cardiac sounds
0.775 0.225 0.000
I20.0 Unstable angina
0.774 0.226 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.774 0.226 0.000
R63.4 Abnormal weight loss
0.773 0.227 0.000
F80-F89 Disorders of psychological development
0.772 0.228 0.000
F32 Depressive episode
0.772 0.228 0.000
I27.0 Primary pulmonary hypertension
0.769 0.231 0.000
R61 Hyperhidrosis
0.769 0.231 0.000
J60-J70 Lung diseases due to external agents
0.769 0.231 0.000
Y43.4 Immunosuppressive agents
0.769 0.231 0.000
M05-M14 Inflammatory polyarthropathies
0.768 0.232 0.000
M77.4 Metatarsalgia
0.767 0.233 0.000
J92 Pleural plaque
0.767 0.233 0.000
I61 Intracerebral haemorrhage
0.765 0.235 0.000
M47.2 Other spondylosis with radiculopathy
0.764 0.236 0.000
H33.0 Retinal detachment with retinal break
0.764 0.236 0.000
R04 Haemorrhage from respiratory passages
0.764 0.236 0.000
H54.0 Blindness, both eyes
0.764 0.236 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.763 0.237 0.000
C61 Malignant neoplasm of prostate
0.762 0.238 0.000
M72 Fibroblastic disorders
0.761 0.239 0.000
M77.1 Lateral epicondylitis
0.761 0.239 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.761 0.239 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.760 0.240 0.000
D03 Melanoma in situ
0.758 0.242 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.758 0.242 0.000
M50 Cervical disk disorders
0.758 0.242 0.000
X20-X29 Contact with venomous animals and plants
0.756 0.244 0.000
M91-M94 Chondropathies
0.755 0.244 0.000
Y00-Y09 Assault
0.754 0.246 0.000
M76 Enthesopathies of lower limb, excluding foot
0.753 0.247 0.000
H33.3 Retinal breaks without detachment
0.753 0.247 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.752 0.248 0.000
M77.9 Enthesopathy, unspecified
0.750 0.250 0.000
X50-X57 Overexertion, travel and privation
0.750 0.250 0.000
H35 Other retinal disorders
0.750 0.250 0.000
F99-F99 Unspecified mental disorder
0.750 0.250 0.000
M89.9 Disorder of bone, unspecified
0.749 0.251 0.000
M25.7 Osteophyte
0.748 0.251 0.000
I77.1 Stricture of artery
0.748 0.252 0.000
S82 Fracture of lower leg, including ankle
0.748 0.252 0.000
Y43.0 Antiallergic and antiemetic drugs
0.745 0.255 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.743 0.257 0.000
F60-F69 Disorders of adult personality and behaviour
0.743 0.257 0.000
M53 Other dorsopathies, not elsewhere classified
0.743 0.257 0.000
I20.8 Other forms of angina pectoris
0.742 0.258 0.000
Y44 Agents primarily affecting blood constituents
0.742 0.258 0.000
D46 Myelodysplastic syndromes
0.741 0.258 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.741 0.259 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.740 0.260 0.000
R87 Abnormal findings in specimens from female genital organs
0.739 0.261 0.000
I30-I52 Other forms of heart disease
0.738 0.262 0.000
S27.0 Traumatic pneumothorax
0.732 0.268 0.000
W20-W49 Exposure to inanimate mechanical forces
0.732 0.268 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.732 0.268 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.731 0.269 0.000
R00.1 Bradycardia, unspecified
0.729 0.271 0.000
M22.8 Other disorders of patella
0.729 0.271 0.000
M00-M03 Infectious arthropathies
0.728 0.272 0.000
M23.8 Other internal derangements of knee
0.728 0.272 0.000
M46 Other inflammatory spondylopathies
0.727 0.273 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.727 0.273 0.000
M54.50 Low back pain (Multiple sites in spine)
0.724 0.276 0.000
C80 Malignant neoplasm without specification of site
0.724 0.276 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.723 0.277 0.000
H26 Other cataract
0.722 0.278 0.000
D09 Carcinoma in situ of other and unspecified sites
0.720 0.280 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.720 0.280 0.000
M77.0 Medial epicondylitis
0.718 0.282 0.000
F17.1 Harmful use
0.718 0.282 0.000
R52 Pain, not elsewhere classified
0.717 0.283 0.000
H53.9 Visual disturbance, unspecified
0.717 0.283 0.000
M47.1 Other spondylosis with myelopathy
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.715 0.285 0.000
M65 Synovitis and tenosynovitis
0.714 0.286 0.000
Chapter VI Diseases of the nervous system
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
M71 Other bursopathies
0.713 0.287 0.000
T14 Injury of unspecified body region
0.713 0.287 0.000
M54.8 Other dorsalgia
0.712 0.287 0.000
M54.0 Panniculitis affecting regions of neck and back
0.712 0.287 0.000
R44.3 Hallucinations, unspecified
0.712 0.288 0.000
R06.1 Stridor
0.711 0.289 0.000
Y40 Systemic antibiotics
0.710 0.290 0.000
J00 Acute nasopharyngitis [common cold]
0.710 0.290 0.000
M47.82 Other spondylosis (Cervical region)
0.709 0.290 0.000
R20.3 Hyperaesthesia
0.709 0.291 0.000
R20.1 Hypoaesthesia of skin
0.709 0.291 0.000
R20.0 Anaesthesia of skin
0.709 0.291 0.000
I69 Sequelae of cerebrovascular disease
0.709 0.291 0.000
S60-S69 Injuries to the wrist and hand
0.709 0.291 0.000
D45 Polycythaemia vera
0.708 0.291 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.707 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.706 0.294 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
S10-S19 Injuries to the neck
0.705 0.295 0.000
R06.7 Sneezing
0.705 0.295 0.000
R06.3 Periodic breathing
0.705 0.295 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.704 0.296 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.704 0.296 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.704 0.296 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.704 0.296 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.704 0.296 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.704 0.296 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.704 0.296 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.701 0.299 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
F32.9 Depressive episode, unspecified
0.701 0.299 0.000
I23 Certain current complications following acute myocardial infarction
0.700 0.300 0.000
H53.8 Other visual disturbances
0.700 0.300 0.000
C15-C26 Malignant neoplasms of digestive organs
0.700 0.300 0.000
S20 Superficial injury of thorax
0.699 0.301 0.000
R22.2 Localised swelling, mass and lump, trunk
0.699 0.301 0.000
M54.6 Pain in thoracic spine
0.698 0.302 0.000
C34 Malignant neoplasm of bronchus and lung
0.698 0.302 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.697 0.303 0.000
I24 Other acute ischaemic heart diseases
0.697 0.303 0.000
S29 Other and unspecified injuries of thorax
0.697 0.303 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.695 0.304 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.695 0.304 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.695 0.304 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.695 0.304 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.695 0.304 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.695 0.304 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.695 0.304 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.695 0.304 0.000
R45 Symptoms and signs involving emotional state
0.695 0.305 0.000
I08 Multiple valve diseases
0.695 0.305 0.000
M24.2 Disorder of ligament
0.695 0.305 0.000
M54.55 Low back pain (Thoracolumbar region)
0.695 0.305 0.000
M54.54 Low back pain-Thoracic
0.695 0.305 0.000
M54.53 Low back pain-Cervicothoracic
0.695 0.305 0.000
M54.52 Low back pain-Cervical
0.695 0.305 0.000
M54.51 Low back pain-Occipit-atl-axl
0.695 0.305 0.000
V20-V29 Motorcycle rider injured in transport accident
0.694 0.306 0.000
J92.9 Pleural plaque without asbestos
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.693 0.306 0.000
M33 Dermatopolymyositis
0.693 0.306 0.000
M32 Systemic lupus erythematosus
0.693 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.693 0.306 0.000
M49 Spondylopathies in diseases classified elsewhere
0.693 0.306 0.000
M25.8 Other specified joint disorders
0.693 0.307 0.000
Y52 Agents primarily affecting the cardiovascular system
0.692 0.308 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.692 0.308 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.692 0.308 0.000
M54.1 Radiculopathy
0.692 0.308 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.692 0.308 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.692 0.308 0.000
S22.1 Multiple fractures of thoracic spine
0.691 0.309 0.000
R22.1 Localised swelling, mass and lump, neck
0.691 0.309 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.691 0.309 0.000
Chapter XXII Codes for special purposes
0.690 0.309 0.000
F10.1 Harmful use
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.690 0.310 0.000
Y58 Bacterial vaccines
0.690 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.690 0.310 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
Y48 Anaesthetics and therapeutic gases
0.690 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.690 0.310 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.690 0.310 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
F17.2 Dependence syndrome
0.690 0.310 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.690 0.310 0.000
H33.5 Other retinal detachments
0.689 0.311 0.000
I50 Heart failure
0.689 0.311 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.688 0.312 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.687 0.312 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.687 0.313 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.687 0.313 0.000
I67.1 Cerebral aneurysm, nonruptured
0.685 0.314 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.685 0.315 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.685 0.315 0.000
I67.5 Moyamoya disease
0.685 0.315 0.000
I67.4 Hypertensive encephalopathy
0.685 0.315 0.000
I67.3 Progressive vascular leukoencephalopathy
0.685 0.315 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.685 0.315 0.000
T33-T35 Frostbite
0.684 0.315 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.684 0.315 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.684 0.315 0.000
T00-T07 Injuries involving multiple body regions
0.684 0.315 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.684 0.316 0.000
W07 Fall involving chair
0.684 0.316 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.684 0.316 0.000
R63.5 Abnormal weight gain
0.684 0.316 0.000
R63.3 Feeding difficulties and mismanagement
0.684 0.316 0.000
R63.2 Polyphagia
0.684 0.316 0.000
R63.1 Polydipsia
0.684 0.316 0.000
H44 Disorders of globe
0.684 0.316 0.000
R60.0 Localised oedema
0.684 0.316 0.000
R46 Symptoms and signs involving appearance and behaviour
0.684 0.316 0.000
R43 Disturbances of smell and taste
0.684 0.316 0.000
R44.0 Auditory hallucinations
0.683 0.317 0.000
F10.9 Unspecified mental and behavioural disorder
0.683 0.317 0.000
F10.8 Other mental and behavioural disorders
0.683 0.317 0.000
F10.7 Residual and late-onset psychotic disorder
0.683 0.317 0.000
F10.6 Amnesic syndrome
0.683 0.317 0.000
F10.5 Psychotic disorder
0.683 0.317 0.000
F10.4 Withdrawal state with delirium
0.683 0.317 0.000
R59.9 Enlarged lymph nodes, unspecified
0.682 0.318 0.000
R06.8 Other and unspecified abnormalities of breathing
0.682 0.318 0.000
I63.8 Other cerebral infarction
0.682 0.318 0.000
Y42.7 Androgens and anabolic congeners
0.681 0.319 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.681 0.319 0.000
R06.4 Hyperventilation
0.680 0.320 0.000
R68 Other general symptoms and signs
0.680 0.320 0.000
F31.9 Bipolar affective disorder, unspecified
0.680 0.320 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
M25.3 Other instability of joint
0.679 0.321 0.000
R56.0 Febrile convulsions
0.678 0.322 0.000
M34 Systemic sclerosis
0.678 0.322 0.000
I70 Atherosclerosis
0.678 0.322 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.677 0.323 0.000
M48 Other spondylopathies
0.677 0.323 0.000
J11 Influenza, virus not identified
0.677 0.323 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.676 0.324 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.676 0.324 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.675 0.325 0.000
I28 Other diseases of pulmonary vessels
0.675 0.325 0.000
S50-S59 Injuries to the elbow and forearm
0.674 0.326 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.672 0.327 0.000
M77.47 Metatarsalgia-Ankle/Foot
0.672 0.328 0.000
M66 Spontaneous rupture of synovium and tendon
0.671 0.329 0.000
Y43.9 Primarily systemic agent, unspecified
0.671 0.329 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.671 0.329 0.000
Y43.6 Enzymes, not elsewhere classified
0.671 0.329 0.000
Y43.5 Acidifying and alkalising agents
0.671 0.329 0.000
Y43.2 Antineoplastic natural products
0.671 0.329 0.000
Y43.1 Antineoplastic antimetabolites
0.671 0.329 0.000
J01 Acute sinusitis
0.670 0.329 0.000
F38 Other mood [affective] disorders
0.670 0.330 0.000
F34 Persistent mood [affective] disorders
0.670 0.330 0.000
F30 Manic episode
0.670 0.330 0.000
F39 Unspecified mood [affective] disorder
0.670 0.330 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.670 0.330 0.000
M24.0 Loose body in joint
0.669 0.331 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.668 0.332 0.000
M13 Other arthritis
0.668 0.332 0.000
M23.0 Cystic meniscus
0.668 0.332 0.000
Chapter VIII Diseases of the ear and mastoid process
0.667 0.333 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.667 0.333 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.667 0.333 0.000
M23.4 Loose body in knee
0.667 0.333 0.000
M90 Osteopathies in diseases classified elsewhere
0.666 0.334 0.000
M84 Disorders of continuity of bone
0.666 0.334 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.666 0.334 0.000
S26 Injury of heart
0.666 0.334 0.000
S25 Injury of blood vessels of thorax
0.666 0.334 0.000
S24 Injury of nerves and spinal cord at thorax level
0.666 0.334 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.666 0.334 0.000
S21 Open wound of thorax
0.666 0.334 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.666 0.334 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.665 0.334 0.000
H31 Other disorders of choroid
0.665 0.334 0.000
H30 Chorioretinal inflammation
0.665 0.334 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.665 0.335 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.665 0.335 0.000
R04.2 Haemoptysis
0.663 0.337 0.000
H43.1 Vitreous haemorrhage
0.663 0.337 0.000
S82.8 Fractures of other parts of lower leg
0.662 0.338 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.662 0.338 0.000
M23.5 Chronic instability of knee
0.662 0.338 0.000
J02 Acute pharyngitis
0.662 0.338 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.662 0.338 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.661 0.339 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.661 0.339 0.000
S27.3 Other injuries of lung
0.661 0.339 0.000
M47.89 Other spondylosis (Site unspecified)
0.660 0.340 0.000
R41.2 Retrograde amnesia
0.659 0.341 0.000
R41.1 Anterograde amnesia
0.659 0.341 0.000
R87.6 Abnormal cytological findings
0.659 0.341 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.658 0.342 0.000
C80.9 Malignant neoplasm, unspecified
0.657 0.343 0.000
H53.6 Night blindness
0.657 0.343 0.000
H53.5 Colour vision deficiencies
0.657 0.343 0.000
H53.3 Other disorders of binocular vision
0.657 0.343 0.000
M40-M43 Deforming dorsopathies
0.657 0.343 0.000
H54.6 Unqualified visual loss, one eye
0.657 0.343 0.000
H54.5 Low vision, one eye
0.657 0.343 0.000
H54.3 Unqualified visual loss, both eyes
0.657 0.343 0.000
H54.2 Low vision, both eyes
0.657 0.343 0.000
H54.1 Blindness, one eye, low vision, other eye
0.657 0.343 0.000
L03 Cellulitis
0.657 0.343 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.656 0.344 0.000
R59.0 Localised enlarged lymph nodes
0.656 0.344 0.000
M21.0 Valgus deformity, not elsewhere classified
0.655 0.345 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.654 0.346 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.654 0.346 0.000
H16 Keratitis
0.654 0.346 0.000
Q60-Q64 Congenital malformations of the urinary system
0.653 0.347 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.653 0.347 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.653 0.347 0.000
I73 Other peripheral vascular diseases
0.652 0.348 0.000
Y57 Other and unspecified drugs and medicaments
0.652 0.348 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.651 0.349 0.000
R23 Other skin changes
0.651 0.349 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.650 0.349 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.649 0.351 0.000
M25.0 Haemarthrosis
0.649 0.351 0.000
M50.3 Other cervical disk degeneration
0.648 0.352 0.000
H21 Other disorders of iris and ciliary body
0.648 0.352 0.000
M54.2 Cervicalgia
0.647 0.353 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.647 0.353 0.000
J21 Acute bronchiolitis
0.647 0.353 0.000
J20 Acute bronchitis
0.647 0.353 0.000
F33 Recurrent depressive disorder
0.647 0.353 0.000
S70-S79 Injuries to the hip and thigh
0.646 0.354 0.000
R57.2 Septic shock
0.646 0.354 0.000
X60-X84 Intentional self-harm
0.646 0.354 0.000
C34.9 Bronchus or lung, unspecified
0.646 0.354 0.000
M21.1 Varus deformity, not elsewhere classified
0.646 0.354 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.645 0.355 0.000
M77.5 Other enthesopathy of foot
0.645 0.355 0.000
M77.3 Calcaneal spur
0.645 0.355 0.000
M77.2 Periarthritis of wrist
0.645 0.355 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.645 0.355 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.645 0.355 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.645 0.355 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.645 0.355 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.645 0.355 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.645 0.355 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.644 0.356 0.000
Y42.5 Other oestrogens and progestogens
0.644 0.356 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.643 0.357 0.000
M21.2 Flexion deformity
0.642 0.357 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.642 0.358 0.000
S90-S99 Injuries to the ankle and foot
0.642 0.358 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.642 0.358 0.000
H36 Retinal disorders in diseases classified elsewhere
0.641 0.359 0.000
M86 Osteomyelitis
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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