TreeWAS – Variant ID: rs1480382

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.999	0.001	0.000
Chapter VII Diseases of the eye and adnexa	0.999	0.001	0.000
J45 Asthma	0.999	0.001	0.000
J40-J47 Chronic lower respiratory diseases	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
D60-D64 Aplastic and other anaemias	0.999	0.001	0.000
Chapter X Diseases of the respiratory system	0.998	0.002	0.000
D64 Other anaemias	0.998	0.002	0.000
D50-D53 Nutritional anaemias	0.997	0.003	0.000
H30-H36 Disorders of choroid and retina	0.996	0.004	0.000
D64.9 Anaemia, unspecified	0.996	0.004	0.000
E10.3 With ophthalmic complications	0.995	0.005	0.000
E10.1 With ketoacidosis	0.995	0.005	0.000
H10-H13 Disorders of conjunctiva	0.995	0.005	0.000
H35 Other retinal disorders	0.994	0.006	0.000
M05 Seropositive rheumatoid arthritis	0.990	0.010	0.000
J44 Other chronic obstructive pulmonary disease	0.989	0.011	0.000
H11 Other disorders of conjunctiva	0.989	0.011	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.989	0.011	0.000
D00-D09 In situ neoplasms	0.989	0.011	0.000
D50 Iron deficiency anaemia	0.988	0.012	0.000
Chapter II Neoplasms	0.988	0.012	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.986	0.014	0.000
J95-J99 Other diseases of the respiratory system	0.984	0.016	0.000
D50.9 Iron deficiency anaemia, unspecified	0.981	0.019	0.000
D06 Carcinoma in situ of cervix uteri	0.981	0.019	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.977	0.023	0.000
D06.9 Cervix, unspecified	0.977	0.023	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.977	0.023	0.000
M06.0 Seronegative rheumatoid arthritis	0.972	0.028	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.972	0.028	0.000
H35.6 Retinal haemorrhage	0.970	0.030	0.000
H36 Retinal disorders in diseases classified elsewhere	0.965	0.035	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.962	0.038	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.962	0.038	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.960	0.040	0.000
H11.0 Pterygium	0.959	0.041	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.958	0.042	0.000
C91 Lymphoid leukaemia	0.949	0.051	0.000
H36.0 Diabetic retinopathy	0.943	0.057	0.000
G35 Multiple sclerosis	0.000	0.057	0.943
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.941	0.059	0.000
C81 Hodgkin's disease	0.940	0.060	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.939	0.061	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.938	0.062	0.000
E10.2 With renal complications	0.937	0.063	0.000
C71 Malignant neoplasm of brain	0.935	0.065	0.000
M45-M49 Spondylopathies	0.935	0.065	0.000
E20-E35 Disorders of other endocrine glands	0.933	0.067	0.000
M20-M25 Other joint disorders	0.928	0.072	0.000
H35.8 Other specified retinal disorders	0.928	0.072	0.000
C83.3 Large cell (diffuse)	0.928	0.072	0.000
J84 Other interstitial pulmonary diseases	0.928	0.072	0.000
D80-D89 Certain disorders involving the immune mechanism	0.927	0.073	0.000
E10.0 With coma	0.925	0.075	0.000
M35 Other systemic involvement of connective tissue	0.923	0.077	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.920	0.080	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.918	0.082	0.000
J95.0 Tracheostomy malfunction	0.917	0.083	0.000
M35.0 Sicca syndrome [Sjogren]	0.917	0.083	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.916	0.084	0.000
J98 Other respiratory disorders	0.915	0.085	0.000
M45 Ankylosing spondylitis	0.914	0.086	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.914	0.086	0.000
E27 Other disorders of adrenal gland	0.913	0.087	0.000
E27.1 Primary adrenocortical insufficiency	0.911	0.089	0.000
D04 Carcinoma in situ of skin	0.910	0.090	0.000
E10.8 With unspecified complications	0.910	0.090	0.000
C81.9 Hodgkin's disease, unspecified	0.901	0.099	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.900	0.100	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.899	0.101	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.898	0.102	0.000
D03 Melanoma in situ	0.893	0.107	0.000
H35.4 Peripheral retinal degeneration	0.891	0.109	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.890	0.110	0.000
M34 Systemic sclerosis	0.890	0.110	0.000
H35.2 Other proliferative retinopathy	0.886	0.114	0.000
H35.0 Background retinopathy and retinal vascular changes	0.885	0.115	0.000
M06.4 Inflammatory polyarthropathy	0.881	0.119	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.881	0.119	0.000
H11.1 Conjunctival degenerations and deposits	0.880	0.120	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.879	0.121	0.000
D64.8 Other specified anaemias	0.878	0.122	0.000
H10 Conjunctivitis	0.874	0.126	0.000
D86 Sarcoidosis	0.874	0.126	0.000
J43 Emphysema	0.871	0.129	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.856	0.144	0.000
D61 Other aplastic anaemias	0.855	0.145	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.852	0.148	0.000
H53-H54 Visual disturbances and blindness	0.851	0.149	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.851	0.149	0.000
M32 Systemic lupus erythematosus	0.850	0.150	0.000
H16 Keratitis	0.850	0.150	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.849	0.151	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.848	0.152	0.000
E24 Cushing's syndrome	0.848	0.152	0.000
E10.4 With neurological complications	0.847	0.153	0.000
C91.1 Chronic lymphocytic leukaemia	0.845	0.155	0.000
H11.9 Disorder of conjunctiva, unspecified	0.843	0.157	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.843	0.157	0.000
E10.5 With peripheral circulatory complications	0.838	0.162	0.000
D04.7 Skin of lower limb, including hip	0.837	0.163	0.000
M05.8 Other seropositive rheumatoid arthritis	0.837	0.163	0.000
H43-H45 Disorders of vitreous body and globe	0.832	0.168	0.000
D52 Folate deficiency anaemia	0.831	0.169	0.000
C07 Malignant neoplasm of parotid gland	0.831	0.169	0.000
C71.0 Cerebrum, except lobes and ventricles	0.827	0.173	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.826	0.174	0.000
E07 Other disorders of thyroid	0.825	0.175	0.000
C91.4 Hairy-cell leukaemia	0.824	0.176	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.822	0.178	0.000
D07.4 Penis	0.822	0.178	0.000
D50.8 Other iron deficiency anaemias	0.821	0.179	0.000
C71.1 Frontal lobe	0.820	0.180	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.819	0.181	0.000
H53 Visual disturbances	0.818	0.182	0.000
D51 Vitamin B12 deficiency anaemia	0.814	0.186	0.000
D53 Other nutritional anaemias	0.810	0.190	0.000
E83.1 Disorders of iron metabolism	0.000	0.190	0.810
H15 Disorders of sclera	0.810	0.190	0.000
C83.1 Small cleaved cell (diffuse)	0.808	0.192	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.808	0.192	0.000
C91.9 Lymphoid leukaemia, unspecified	0.808	0.192	0.000
M13 Other arthritis	0.807	0.193	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.807	0.193	0.000
E70-E90 Metabolic disorders	0.807	0.193	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.803	0.197	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.803	0.197	0.000
D50.1 Sideropenic dysphagia	0.800	0.200	0.000
D09 Carcinoma in situ of other and unspecified sites	0.799	0.201	0.000
E10.7 With multiple complications	0.797	0.203	0.000
H53.1 Subjective visual disturbances	0.796	0.204	0.000
M12 Other specific arthropathies	0.796	0.204	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.790	0.210	0.000
D04.5 Skin of trunk	0.788	0.212	0.000
M05.0 Felty's syndrome	0.786	0.214	0.000
D07.1 Vulva	0.785	0.215	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.784	0.216	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.784	0.216	0.000
M10 Gout	0.781	0.219	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.781	0.219	0.000
C81.1 Nodular sclerosis	0.780	0.220	0.000
M34.9 Systemic sclerosis, unspecified	0.780	0.220	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.778	0.222	0.000
C71.9 Brain, unspecified	0.777	0.223	0.000
E10.6 With other specified complications	0.777	0.223	0.000
E89.0 Postprocedural hypothyroidism	0.777	0.223	0.000
M13.8 Other specified arthritis	0.775	0.225	0.000
C69 Malignant neoplasm of eye and adnexa	0.769	0.231	0.000
J43.9 Emphysema, unspecified	0.768	0.232	0.000
C71.3 Parietal lobe	0.767	0.233	0.000
D86.9 Sarcoidosis, unspecified	0.766	0.234	0.000
J98.4 Other disorders of lung	0.765	0.235	0.000
E85 Amyloidosis	0.763	0.237	0.000
C71.8 Overlapping lesion of brain	0.762	0.238	0.000
H43 Disorders of vitreous body	0.761	0.239	0.000
C83.7 Burkitt's tumour	0.761	0.239	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.760	0.240	0.000
M35.7 Hypermobility syndrome	0.760	0.240	0.000
D61.9 Aplastic anaemia, unspecified	0.756	0.244	0.000
H10.9 Conjunctivitis, unspecified	0.753	0.247	0.000
E28 Ovarian dysfunction	0.753	0.247	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.752	0.248	0.000
C04 Malignant neoplasm of floor of mouth	0.751	0.249	0.000
H30 Chorioretinal inflammation	0.751	0.249	0.000
M46 Other inflammatory spondylopathies	0.750	0.250	0.000
J45.1 Nonallergic asthma	0.747	0.253	0.000
M22 Disorders of patella	0.746	0.254	0.000
H43.8 Other disorders of vitreous body	0.746	0.254	0.000
E16 Other disorders of pancreatic internal secretion	0.746	0.254	0.000
D07.2 Vagina	0.745	0.255	0.000
E06 Thyroiditis	0.745	0.255	0.000
M34.0 Progressive systemic sclerosis	0.745	0.255	0.000
M34.1 CR(E)ST syndrome	0.744	0.256	0.000
M08 Juvenile arthritis	0.743	0.257	0.000
C70 Malignant neoplasm of meninges	0.743	0.257	0.000
C10 Malignant neoplasm of oropharynx	0.742	0.258	0.000
H10.1 Acute atopic conjunctivitis	0.741	0.259	0.000
H16.9 Keratitis, unspecified	0.740	0.260	0.000
M05.1 Rheumatoid lung disease	0.740	0.260	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.261	0.736
H15.8 Other disorders of sclera	0.736	0.263	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.736	0.264	0.000
D04.9 Skin, unspecified	0.735	0.265	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.732	0.268	0.000
C03 Malignant neoplasm of gum	0.732	0.268	0.000
C88 Malignant immunoproliferative diseases	0.732	0.268	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.732	0.268	0.000
J45.8 Mixed asthma	0.731	0.269	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.731	0.269	0.000
M35.1 Other overlap syndromes	0.730	0.270	0.000
M00-M03 Infectious arthropathies	0.730	0.270	0.000
D86.3 Sarcoidosis of skin	0.727	0.273	0.000
M60-M63 Disorders of muscles	0.724	0.276	0.000
K90 Intestinal malabsorption	0.723	0.277	0.000
H53.9 Visual disturbance, unspecified	0.721	0.279	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M13.80 Other specified arthritis (Multiple sites)	0.715	0.285	0.000
D64.4 Congenital dyserythropoietic anaemia	0.715	0.285	0.000
D64.3 Other sideroblastic anaemias	0.715	0.285	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.715	0.285	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.715	0.285	0.000
D64.0 Hereditary sideroblastic anaemia	0.715	0.285	0.000
C71.7 Brain stem	0.715	0.285	0.000
M49 Spondylopathies in diseases classified elsewhere	0.714	0.286	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.714	0.286	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.714	0.286	0.000
D52.9 Folate deficiency anaemia, unspecified	0.713	0.287	0.000
H35.1 Retinopathy of prematurity	0.712	0.288	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.711	0.289	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.710	0.290	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.710	0.290	0.000
H16.8 Other keratitis	0.710	0.290	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.709	0.291	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.707	0.293	0.000
C94 Other leukaemias of specified cell type	0.707	0.293	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.706	0.294	0.000
J96 Respiratory failure, not elsewhere classified	0.705	0.294	0.000
D86.8 Sarcoidosis of other and combined sites	0.705	0.295	0.000
E31 Polyglandular dysfunction	0.704	0.296	0.000
E07.8 Other specified disorders of thyroid	0.704	0.296	0.000
M05.2 Rheumatoid vasculitis	0.704	0.296	0.000
C13 Malignant neoplasm of hypopharynx	0.704	0.296	0.000
D06.7 Other parts of cervix	0.703	0.297	0.000
E24.2 Drug-induced Cushing's syndrome	0.702	0.298	0.000
H20 Iridocyclitis	0.701	0.298	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.701	0.299	0.000
M34.8 Other forms of systemic sclerosis	0.701	0.299	0.000
M32.8 Other forms of systemic lupus erythematosus	0.699	0.301	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.699	0.301	0.000
C91.5 Adult T-cell leukaemia	0.698	0.302	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.697	0.303	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.697	0.303	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.697	0.303	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.697	0.303	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.697	0.303	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.697	0.303	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.697	0.303	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.697	0.303	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.697	0.303	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.697	0.303	0.000
M06.8 Other specified rheumatoid arthritis	0.696	0.304	0.000
H53.4 Visual field defects	0.696	0.304	0.000
D06.1 Exocervix	0.695	0.304	0.000
M22.2 Patellofemoral disorders	0.695	0.305	0.000
M11 Other crystal arthropathies	0.694	0.306	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.306	0.693
J41 Simple and mucopurulent chronic bronchitis	0.693	0.306	0.000
C05 Malignant neoplasm of palate	0.693	0.307	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.692	0.308	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.692	0.308	0.000
E03.8 Other specified hypothyroidism	0.691	0.309	0.000
M35.3 Polymyalgia rheumatica	0.691	0.309	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.691	0.309	0.000
C85.0 Lymphosarcoma	0.690	0.310	0.000
M46.4 Discitis, unspecified	0.689	0.311	0.000
C83.6 Undifferentiated (diffuse)	0.688	0.312	0.000
C83.5 Lymphoblastic (diffuse)	0.688	0.312	0.000
C83.4 Immunoblastic (diffuse)	0.688	0.312	0.000
C83.2 Mixed small and large cell (diffuse)	0.688	0.312	0.000
E24.8 Other Cushing's syndrome	0.685	0.315	0.000
H16.2 Keratoconjunctivitis	0.684	0.316	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.684	0.316	0.000
E85.9 Amyloidosis, unspecified	0.682	0.318	0.000
D61.1 Drug-induced aplastic anaemia	0.682	0.318	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.681	0.319	0.000
C91.7 Other lymphoid leukaemia	0.681	0.319	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.681	0.319	0.000
C91.3 Prolymphocytic leukaemia	0.681	0.319	0.000
C91.2 Subacute lymphocytic leukaemia	0.681	0.319	0.000
C69.3 Choroid	0.679	0.321	0.000
C71.4 Occipital lobe	0.679	0.321	0.000
L10-L14 Bullous disorders	0.679	0.321	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.679	0.321	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.678	0.322	0.000
C14.0 Pharynx, unspecified	0.678	0.322	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.677	0.323	0.000
J84.0 Alveolar and parietoalveolar conditions	0.676	0.324	0.000
D53.9 Nutritional anaemia, unspecified	0.676	0.324	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.675	0.325	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.674	0.326	0.000
C81.7 Other Hodgkin's disease	0.674	0.326	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.674	0.326	0.000
C81.3 Lymphocytic depletion	0.674	0.326	0.000
J95.5 Postprocedural subglottic stenosis	0.673	0.327	0.000
J95.4 Mendelson's syndrome	0.673	0.327	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.673	0.327	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.673	0.327	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.673	0.327	0.000
E23 Hypofunction and other disorders of pituitary gland	0.671	0.329	0.000
C12 Malignant neoplasm of pyriform sinus	0.671	0.329	0.000
C71.6 Cerebellum	0.670	0.329	0.000
C71.5 Cerebral ventricle	0.670	0.329	0.000
E24.9 Cushing's syndrome, unspecified	0.669	0.331	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.669	0.331	0.000
E32 Diseases of thymus	0.669	0.331	0.000
E30 Disorders of puberty, not elsewhere classified	0.669	0.331	0.000
E25 Adrenogenital disorders	0.669	0.331	0.000
C86 Other specified types of T/NK-cell lymphoma	0.668	0.331	0.000
M13.89 Other specified arthritis (Site unspecified)	0.667	0.333	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.667	0.333	0.000
D04.4 Skin of scalp and neck	0.667	0.333	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.334	0.666
D81 Combined immunodeficiencies	0.665	0.335	0.000
M86-M90 Other osteopathies	0.665	0.335	0.000
E13 Other specified diabetes mellitus	0.664	0.336	0.000
M10.0 Idiopathic gout	0.664	0.336	0.000
J98.2 Interstitial emphysema	0.663	0.337	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.662	0.337	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.662	0.338	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.662	0.338	0.000
M35.5 Multifocal fibrosclerosis	0.662	0.338	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.662	0.338	0.000
D89.1 Cryoglobulinaemia	0.661	0.339	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.661	0.339	0.000
D03.8 Melanoma in situ of other sites	0.660	0.340	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.660	0.340	0.000
D04.3 Skin of other and unspecified parts of face	0.660	0.340	0.000
M06.3 Rheumatoid nodule	0.659	0.341	0.000
D09.1 Other and unspecified urinary organs	0.659	0.341	0.000
M07 Psoriatic and enteropathic arthropathies	0.658	0.342	0.000
H53.3 Other disorders of binocular vision	0.657	0.343	0.000
J98.3 Compensatory emphysema	0.656	0.344	0.000
C95 Leukaemia of unspecified cell type	0.655	0.345	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.655	0.345	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.655	0.345	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.655	0.345	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.655	0.345	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.655	0.345	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.655	0.345	0.000
E05.8 Other thyrotoxicosis	0.655	0.345	0.000
E27.5 Adrenomedullary hyperfunction	0.655	0.345	0.000
E27.0 Other adrenocortical overactivity	0.655	0.345	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.655	0.345	0.000
L94 Other localised connective tissue disorders	0.655	0.345	0.000
D86.1 Sarcoidosis of lymph nodes	0.654	0.345	0.000
C93 Monocytic leukaemia	0.654	0.346	0.000
E27.8 Other specified disorders of adrenal gland	0.654	0.346	0.000
C91.0 Acute lymphoblastic leukaemia	0.653	0.347	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.653	0.347	0.000
D04.8 Skin of other sites	0.652	0.348	0.000
D04.0 Skin of lip	0.652	0.348	0.000
H16.0 Corneal ulcer	0.652	0.348	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.652	0.348	0.000
H11.8 Other specified disorders of conjunctiva	0.651	0.348	0.000
M30 Polyarteritis nodosa and related conditions	0.650	0.350	0.000
H15.9 Disorder of sclera, unspecified	0.649	0.350	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.649	0.351	0.000
E29 Testicular dysfunction	0.649	0.351	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.649	0.351	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.647	0.353	0.000
E24.0 Pituitary-dependent Cushing's disease	0.647	0.353	0.000
E14 Unspecified diabetes mellitus	0.646	0.354	0.000
J43.8 Other emphysema	0.646	0.354	0.000
H16.4 Corneal neovascularisation	0.645	0.355	0.000
D06.0 Endocervix	0.644	0.356	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.644	0.356	0.000
D07.6 Other and unspecified male genital organs	0.644	0.356	0.000
D07.3 Other and unspecified female genital organs	0.644	0.356	0.000
D07.0 Endometrium	0.644	0.356	0.000
E03.1 Congenital hypothyroidism without goitre	0.643	0.356	0.000
E40-E46 Malnutrition	0.643	0.357	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.643	0.357	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.643	0.357	0.000
D82 Immunodeficiency associated with other major defects	0.641	0.359	0.000
D03.9 Melanoma in situ, unspecified	0.640	0.359	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.640	0.359	0.000
D03.0 Melanoma in situ of lip	0.640	0.359	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.640	0.360	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.640	0.360	0.000
M05.09 Felty's syndrome (Site unspecified)	0.640	0.360	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.638	0.362	0.000
D01.3 Anus and anal canal	0.637	0.363	0.000
H43.9 Disorder of vitreous body, unspecified	0.636	0.364	0.000
C81.0 Lymphocytic predominance	0.636	0.364	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.634	0.365	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.634	0.366	0.000
E28.3 Primary ovarian failure	0.634	0.366	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.633	0.367	0.000
J43.2 Centrilobular emphysema	0.632	0.368	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.632	0.368	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.632	0.368	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.632	0.368	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.632	0.368	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.632	0.368	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.632	0.368	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.632	0.368	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.632	0.368	0.000
J81 Pulmonary oedema	0.631	0.369	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.631	0.369	0.000
K50.9 Crohn's disease, unspecified	0.000	0.370	0.630
Q00-Q07 Congenital malformations of the nervous system	0.630	0.370	0.000
D55-D59 Haemolytic anaemias	0.629	0.370	0.000
D62 Acute posthaemorrhagic anaemia	0.629	0.371	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.629	0.371	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.371	0.628
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.628	0.371	0.000
D03.4 Melanoma in situ of scalp and neck	0.627	0.373	0.000
H10.8 Other conjunctivitis	0.627	0.373	0.000
H10.5 Blepharoconjunctivitis	0.627	0.373	0.000
H10.3 Acute conjunctivitis, unspecified	0.627	0.373	0.000
H10.2 Other acute conjunctivitis	0.627	0.373	0.000
H10.0 Mucopurulent conjunctivitis	0.627	0.373	0.000
D86.0 Sarcoidosis of lung	0.627	0.373	0.000
M21 Other acquired deformities of limbs	0.626	0.374	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.626	0.374	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.625	0.375	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.625	0.375	0.000
J43.1 Panlobular emphysema	0.624	0.375	0.000
J43.0 MacLeod's syndrome	0.624	0.375	0.000
C00 Malignant neoplasm of lip	0.624	0.375	0.000
D02.0 Larynx	0.624	0.376	0.000
M35.2 Behcet's disease	0.623	0.377	0.000
K50.0 Crohn's disease of small intestine	0.000	0.379	0.621
D84 Other immunodeficiencies	0.620	0.379	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.620	0.380	0.000
M35.8 Other specified systemic involvement of connective tissue	0.620	0.380	0.000
M14 Arthropathies in other diseases classified elsewhere	0.619	0.380	0.000
H20.9 Iridocyclitis, unspecified	0.617	0.382	0.000
E85.4 Organ-limited amyloidosis	0.617	0.383	0.000
C10.9 Oropharynx, unspecified	0.616	0.384	0.000
L82 Seborrhoeic keratosis	0.614	0.386	0.000
C11 Malignant neoplasm of nasopharynx	0.613	0.386	0.000
D61.8 Other specified aplastic anaemias	0.613	0.387	0.000
D61.3 Idiopathic aplastic anaemia	0.613	0.387	0.000
D61.2 Aplastic anaemia due to other external agents	0.613	0.387	0.000
E70 Disorders of aromatic amino-acid metabolism	0.613	0.387	0.000
E85.3 Secondary systemic amyloidosis	0.613	0.387	0.000
M60 Myositis	0.612	0.388	0.000
M12.2 Villonodular synovitis (pigmented)	0.612	0.388	0.000
E65-E68 Obesity and other hyperalimentation	0.611	0.389	0.000
E15 Nondiabetic hypoglycaemic coma	0.611	0.389	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.609	0.391	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.609	0.391	0.000
M46.0 Spinal enthesopathy	0.609	0.391	0.000
H16.3 Interstitial and deep keratitis	0.609	0.391	0.000
E06.3 Autoimmune thyroiditis	0.609	0.391	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.608	0.392	0.000
E24.3 Ectopic ACTH syndrome	0.608	0.392	0.000
E24.1 Nelson's syndrome	0.608	0.392	0.000
H31 Other disorders of choroid	0.607	0.392	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.607	0.393	0.000
C81.2 Mixed cellularity	0.606	0.394	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.606	0.394	0.000
C04.0 Anterior floor of mouth	0.604	0.396	0.000
D09.9 Carcinoma in situ, unspecified	0.604	0.396	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.604	0.396	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.604	0.396	0.000
Q50-Q56 Congenital malformations of genital organs	0.603	0.397	0.000
E89.4 Postprocedural ovarian failure	0.602	0.398	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.602	0.398	0.000
E22 Hyperfunction of pituitary gland	0.602	0.398	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.601	0.399	0.000
H21 Other disorders of iris and ciliary body	0.601	0.399	0.000
E20 Hypoparathyroidism	0.600	0.400	0.000
M48 Other spondylopathies	0.600	0.400	0.000
H35.7 Separation of retinal layers	0.600	0.400	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.600	0.400	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.600	0.400	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.600	0.400	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.600	0.400	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.600	0.400	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.600	0.400	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.600	0.400	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.600	0.400	0.000
D02.2 Bronchus and lung	0.598	0.401	0.000
C03.1 Lower gum	0.598	0.402	0.000
Chapter I Certain infectious and parasitic diseases	0.598	0.402	0.000
D52.8 Other folate deficiency anaemias	0.596	0.404	0.000
D52.1 Drug-induced folate deficiency anaemia	0.596	0.404	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations