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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129954
log Bayes Factor = 177.83
Chromosome 6   position 32,365,580  (GRCh37) Explore rs3129954 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.001 0.999
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
J30-J39 Other diseases of upper respiratory tract
0.000 0.003 0.997
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.003 0.997
L40-L45 Papulosquamous disorders
0.000 0.003 0.997
J33.9 Nasal polyp, unspecified
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.006 0.994
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
# Top node
0.000 0.008 0.992
Chapter X Diseases of the respiratory system
0.000 0.008 0.992
J40-J47 Chronic lower respiratory diseases
0.000 0.011 0.989
J33.8 Other polyp of sinus
0.000 0.012 0.988
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.013 0.987
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.014 0.986
H36 Retinal disorders in diseases classified elsewhere
0.000 0.017 0.983
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.017 0.983
E10.5 With peripheral circulatory complications
0.000 0.017 0.983
G35-G37 Demyelinating diseases of the central nervous system
0.982 0.018 0.000
E14.9 Without complications
0.000 0.018 0.982
G37 Other demyelinating diseases of central nervous system
0.978 0.022 0.000
J32 Chronic sinusitis
0.000 0.022 0.978
J43 Emphysema
0.000 0.024 0.976
G37.9 Demyelinating disease of central nervous system, unspecified
0.974 0.026 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.026 0.974
H30-H36 Disorders of choroid and retina
0.000 0.028 0.972
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.029 0.971
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.032 0.968
L43 Lichen planus
0.000 0.032 0.968
E10.2 With renal complications
0.000 0.033 0.967
J46 Status asthmaticus
0.000 0.036 0.964
J43.9 Emphysema, unspecified
0.000 0.038 0.962
M06.3 Rheumatoid nodule
0.000 0.038 0.962
M06.0 Seronegative rheumatoid arthritis
0.000 0.046 0.954
Chapter VIII Diseases of the ear and mastoid process
0.000 0.047 0.953
J32.9 Chronic sinusitis, unspecified
0.000 0.047 0.953
M20-M25 Other joint disorders
0.000 0.048 0.952
M35.3 Polymyalgia rheumatica
0.000 0.049 0.951
J38.3 Other diseases of vocal cords
0.000 0.049 0.951
M35 Other systemic involvement of connective tissue
0.000 0.051 0.949
H43-H45 Disorders of vitreous body and globe
0.000 0.051 0.949
L43.9 Lichen planus, unspecified
0.000 0.053 0.947
H25-H28 Disorders of lens
0.000 0.055 0.945
M25.46 Effusion of joint (Lower leg)
0.000 0.056 0.944
M25.4 Effusion of joint
0.000 0.062 0.938
M25 Other joint disorders, not elsewhere classified
0.000 0.067 0.933
K90 Intestinal malabsorption
0.000 0.067 0.933
H43 Disorders of vitreous body
0.000 0.070 0.930
H60-H62 Diseases of external ear
0.000 0.072 0.928
J44 Other chronic obstructive pulmonary disease
0.000 0.076 0.924
J38.0 Paralysis of vocal cords and larynx
0.000 0.076 0.924
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.079 0.921
K90-K93 Other diseases of the digestive system
0.000 0.083 0.917
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.084 0.916
E10.0 With coma
0.000 0.084 0.916
M07 Psoriatic and enteropathic arthropathies
0.000 0.085 0.915
Chapter XI Diseases of the digestive system
0.000 0.086 0.914
E11.1 With ketoacidosis
0.000 0.087 0.913
M65-M68 Disorders of synovium and tendon
0.000 0.089 0.911
E10.8 With unspecified complications
0.000 0.089 0.911
H27 Other disorders of lens
0.000 0.092 0.908
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.093 0.907
H25.1 Senile nuclear cataract
0.000 0.098 0.902
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.099 0.901
E06 Thyroiditis
0.000 0.099 0.901
H25 Senile cataract
0.000 0.100 0.900
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.101 0.899
H90-H95 Other disorders of ear
0.000 0.101 0.899
K70-K77 Diseases of liver
0.000 0.102 0.898
E10.6 With other specified complications
0.000 0.106 0.894
M06.34 Rheumatoid nodule (Hand)
0.000 0.109 0.891
H91 Other hearing loss
0.000 0.112 0.888
E11.3 With ophthalmic complications
0.000 0.114 0.886
M65 Synovitis and tenosynovitis
0.000 0.117 0.883
L40.0 Psoriasis vulgaris
0.000 0.120 0.880
H91.9 Hearing loss, unspecified
0.000 0.120 0.880
H60 Otitis externa
0.000 0.122 0.878
E40-E46 Malnutrition
0.000 0.125 0.875
K74 Fibrosis and cirrhosis of liver
0.000 0.125 0.875
K74.3 Primary biliary cirrhosis
0.000 0.130 0.870
M31 Other necrotising vasculopathies
0.000 0.136 0.864
M07.3 Other psoriatic arthropathies
0.000 0.140 0.860
H43.3 Other vitreous opacities
0.000 0.142 0.858
E06.3 Autoimmune thyroiditis
0.000 0.146 0.854
H27.0 Aphakia
0.000 0.146 0.854
M31.6 Other giant cell arteritis
0.000 0.153 0.847
K73 Chronic hepatitis, not elsewhere classified
0.000 0.154 0.846
G37.8 Other specified demyelinating diseases of central nervous system
0.843 0.157 0.000
E11.5 With peripheral circulatory complications
0.000 0.158 0.842
E13 Other specified diabetes mellitus
0.000 0.160 0.840
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.163 0.837
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.164 0.836
J32.4 Chronic pansinusitis
0.000 0.166 0.834
H61 Other disorders of external ear
0.000 0.168 0.832
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.176 0.824
K50-K52 Noninfective enteritis and colitis
0.014 0.177 0.808
J37 Chronic laryngitis and laryngotracheitis
0.000 0.178 0.822
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
M06.4 Inflammatory polyarthropathy
0.000 0.182 0.818
E14.8 With unspecified complications
0.000 0.189 0.811
H43.1 Vitreous haemorrhage
0.000 0.190 0.810
E11.8 With unspecified complications
0.000 0.194 0.806
H27.8 Other specified disorders of lens
0.000 0.194 0.806
H43.8 Other disorders of vitreous body
0.000 0.196 0.804
J38.1 Polyp of vocal cord and larynx
0.000 0.197 0.803
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.197 0.803
J33.0 Polyp of nasal cavity
0.000 0.202 0.798
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.204 0.796
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.205 0.795
E03.8 Other specified hypothyroidism
0.000 0.206 0.794
K50 Crohn's disease [regional enteritis]
0.000 0.209 0.791
M35.1 Other overlap syndromes
0.000 0.211 0.789
J38.6 Stenosis of larynx
0.000 0.211 0.789
E46 Unspecified protein-energy malnutrition
0.000 0.214 0.786
H40-H42 Glaucoma
0.000 0.214 0.786
E14.5 With peripheral circulatory complications
0.000 0.214 0.786
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.215 0.785
E07 Other disorders of thyroid
0.000 0.216 0.784
J32.2 Chronic ethmoidal sinusitis
0.000 0.218 0.782
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.218 0.782
E11.0 With coma
0.000 0.219 0.781
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.221 0.779
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.225 0.775
E14.1 With ketoacidosis
0.000 0.228 0.772
J33.1 Polypoid sinus degeneration
0.000 0.230 0.770
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.231 0.769
E16.1 Other hypoglycaemia
0.000 0.232 0.768
E11.2 With renal complications
0.000 0.233 0.767
J43.2 Centrilobular emphysema
0.000 0.236 0.764
M25.40 Effusion of joint (Multiple sites)
0.000 0.237 0.763
J38.4 Oedema of larynx
0.000 0.240 0.760
K50.8 Other Crohn's disease
0.000 0.240 0.760
H30 Chorioretinal inflammation
0.000 0.240 0.760
M14 Arthropathies in other diseases classified elsewhere
0.000 0.241 0.759
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.244 0.756
K73.9 Chronic hepatitis, unspecified
0.000 0.245 0.755
M34 Systemic sclerosis
0.000 0.246 0.754
K51.9 Ulcerative colitis, unspecified
0.753 0.247 0.000
J86 Pyothorax
0.000 0.249 0.751
H60.3 Other infective otitis externa
0.000 0.252 0.748
M60-M63 Disorders of muscles
0.000 0.254 0.746
J32.8 Other chronic sinusitis
0.000 0.256 0.744
J45 Asthma
0.000 0.257 0.743
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.258 0.742
J41 Simple and mucopurulent chronic bronchitis
0.000 0.259 0.741
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.260 0.740
E11.6 With other specified complications
0.000 0.260 0.740
J43.8 Other emphysema
0.000 0.261 0.739
H61.8 Other specified disorders of external ear
0.000 0.261 0.739
C83.3 Large cell (diffuse)
0.000 0.262 0.738
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.263 0.736
H60.5 Acute otitis externa, non-infective
0.000 0.264 0.735
H60.4 Cholesteatoma of external ear
0.000 0.266 0.734
K51 Ulcerative colitis
0.731 0.267 0.001
H60.1 Cellulitis of external ear
0.000 0.267 0.733
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.270 0.730
M25.43 Effusion of joint (Forearm)
0.000 0.270 0.730
H43.2 Crystalline deposits in vitreous body
0.000 0.273 0.727
E13.9 Without complications
0.000 0.275 0.725
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.276 0.724
L50-L54 Urticaria and erythema
0.000 0.276 0.724
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.000 0.281 0.719
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.282 0.718
M65.8 Other synovitis and tenosynovitis
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L10-L14 Bullous disorders
0.000 0.285 0.715
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
K51.3 Ulcerative (chronic) rectosigmoiditis
0.712 0.288 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.289 0.711
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.290 0.710
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.290 0.710
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.291 0.709
K50.1 Crohn's disease of large intestine
0.000 0.291 0.709
K76 Other diseases of liver
0.000 0.292 0.708
E14.4 With neurological complications
0.000 0.293 0.707
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.295 0.705
H91.1 Presbycusis
0.000 0.296 0.704
M25.0 Haemarthrosis
0.000 0.296 0.704
G37.5 Concentric sclerosis [Balo]
0.701 0.298 0.000
G37.4 Subacute necrotising myelitis
0.701 0.298 0.000
G37.2 Central pontine myelinolysis
0.701 0.298 0.000
G37.1 Central demyelination of corpus callosum
0.701 0.298 0.000
G37.0 Diffuse sclerosis
0.701 0.298 0.000
J43.1 Panlobular emphysema
0.000 0.300 0.700
J43.0 MacLeod's syndrome
0.000 0.300 0.700
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.301 0.699
K76.8 Other specified diseases of liver
0.000 0.301 0.699
L40.1 Generalised pustular psoriasis
0.000 0.302 0.698
M12 Other specific arthropathies
0.000 0.302 0.698
L43.8 Other lichen planus
0.000 0.302 0.698
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.302 0.698
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.303 0.697
H44 Disorders of globe
0.000 0.303 0.697
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.304 0.696
J37.0 Chronic laryngitis
0.000 0.304 0.696
H61.3 Acquired stenosis of external ear canal
0.000 0.305 0.695
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.695
M25.42 Effusion of joint (Upper arm)
0.000 0.305 0.695
M10 Gout
0.000 0.306 0.694
L43.3 Subacute (active) lichen planus
0.000 0.306 0.694
L43.2 Lichenoid drug reaction
0.000 0.306 0.694
L43.1 Bullous lichen planus
0.000 0.306 0.694
L43.0 Hypertrophic lichen planus
0.000 0.306 0.694
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.306 0.694
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.306 0.694
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.308 0.692
M06.8 Other specified rheumatoid arthritis
0.000 0.308 0.692
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.310 0.690
M06.38 Rheumatoid nodule (Other)
0.000 0.310 0.690
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.310 0.690
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.310 0.690
M06.33 Rheumatoid nodule (Forearm)
0.000 0.310 0.690
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.310 0.690
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.310 0.690
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.685 0.315 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.316 0.684
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.316 0.684
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.316 0.684
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.316 0.684
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.316 0.684
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.316 0.684
J32.1 Chronic frontal sinusitis
0.000 0.316 0.684
E03.1 Congenital hypothyroidism without goitre
0.000 0.318 0.682
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.319 0.680
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.319 0.680
M35.5 Multifocal fibrosclerosis
0.000 0.319 0.680
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.319 0.680
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.320 0.680
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.320 0.680
J45.9 Asthma, unspecified
0.000 0.321 0.679
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.322 0.678
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.000 0.323 0.677
M31.9 Necrotising vasculopathy, unspecified
0.000 0.323 0.677
G36 Other acute disseminated demyelination
0.677 0.323 0.000
M25.49 Effusion of joint (Site unspecified)
0.000 0.328 0.672
M25.48 Effusion of joint (Other)
0.000 0.328 0.672
K75 Other inflammatory liver diseases
0.000 0.328 0.672
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.328 0.672
M25.2 Flail joint
0.000 0.331 0.669
M25.1 Fistula of joint
0.000 0.331 0.669
K90.3 Pancreatic steatorrhoea
0.000 0.331 0.669
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.331 0.669
K90.1 Tropical sprue
0.000 0.331 0.669
H43.0 Vitreous prolapse
0.000 0.333 0.667
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.334 0.666
H34 Retinal vascular occlusions
0.000 0.334 0.666
M60 Myositis
0.000 0.334 0.665
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.335 0.665
H91.2 Sudden idiopathic hearing loss
0.000 0.337 0.663
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.000 0.340 0.660
E11.4 With neurological complications
0.000 0.341 0.659
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.342 0.658
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.343 0.657
H61.1 Non-infective disorders of pinna
0.000 0.343 0.657
M07.5 Arthropathy in ulcerative colitis
0.000 0.344 0.656
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.344 0.656
M07.2 Psoriatic spondylitis
0.000 0.344 0.656
M07.1 Arthritis mutilans
0.000 0.344 0.656
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.344 0.656
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.345 0.655
K50.0 Crohn's disease of small intestine
0.000 0.346 0.654
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.347 0.653
E07.9 Disorder of thyroid, unspecified
0.000 0.348 0.652
H40 Glaucoma
0.000 0.348 0.652
H27.9 Disorder of lens, unspecified
0.000 0.349 0.651
M66 Spontaneous rupture of synovium and tendon
0.000 0.349 0.651
J86.0 Pyothorax with fistula
0.000 0.350 0.650
K90.9 Intestinal malabsorption, unspecified
0.000 0.350 0.650
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.350 0.650
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.351 0.649
E06.5 Other chronic thyroiditis
0.000 0.354 0.646
E06.4 Drug-induced thyroiditis
0.000 0.354 0.646
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.354 0.646
E06.0 Acute thyroiditis
0.000 0.354 0.646
H25.2 Senile cataract, morgagnian type
0.000 0.354 0.646
H94 Other disorders of ear in diseases classified elsewhere
0.000 0.355 0.645
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.356 0.644
K77 Liver disorders in diseases classified elsewhere
0.000 0.356 0.644
M25.41 Effusion of joint (Shoulder region)
0.000 0.356 0.644
C82.0 Small cleaved cell, follicular
0.000 0.357 0.643
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.357 0.643
K72 Hepatic failure, not elsewhere classified
0.000 0.358 0.641
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.359 0.641
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.359 0.640
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.360 0.640
M30 Polyarteritis nodosa and related conditions
0.000 0.360 0.640
H40.9 Glaucoma, unspecified
0.000 0.362 0.638
H91.0 Ototoxic hearing loss
0.000 0.363 0.637
J39 Other diseases of upper respiratory tract
0.000 0.363 0.637
H43.9 Disorder of vitreous body, unspecified
0.000 0.364 0.636
L03 Cellulitis
0.000 0.364 0.636
J32.0 Chronic maxillary sinusitis
0.000 0.366 0.634
D86.0 Sarcoidosis of lung
0.634 0.366 0.000
M65.2 Calcific tendinitis
0.000 0.367 0.633
M65.0 Abscess of tendon sheath
0.000 0.367 0.633
L03.0 Cellulitis of finger and toe
0.000 0.368 0.632
K51.8 Other ulcerative colitis
0.631 0.368 0.000
C91 Lymphoid leukaemia
0.000 0.368 0.632
C85.1 B-cell lymphoma, unspecified
0.000 0.370 0.630
H60.2 Malignant otitis externa
0.000 0.370 0.630
H60.0 Abscess of external ear
0.000 0.371 0.629
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.372 0.628
E45 Retarded development following protein-energy malnutrition
0.000 0.372 0.628
E43 Unspecified severe protein-energy malnutrition
0.000 0.372 0.628
E42 Marasmic kwashiorkor
0.000 0.372 0.628
E41 Nutritional marasmus
0.000 0.372 0.628
E40 Kwashiorkor
0.000 0.372 0.628
K74.4 Secondary biliary cirrhosis
0.000 0.372 0.628
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.372 0.628
K74.1 Hepatic sclerosis
0.000 0.372 0.628
M05.2 Rheumatoid vasculitis
0.000 0.373 0.626
M07.6 Other enteropathic arthropathies
0.000 0.377 0.623
J86.9 Pyothorax without fistula
0.000 0.379 0.621
M31.8 Other specified necrotising vasculopathies
0.000 0.380 0.619
M31.7 Microscopic polyangiitis
0.000 0.380 0.619
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.380 0.619
M31.2 Lethal midline granuloma
0.000 0.380 0.619
K75.4 Autoimmune hepatitis
0.000 0.381 0.619
M14.6 Neuropathic arthropathy
0.000 0.381 0.619
M07.38 Other psoriatic arthropathies (Other)
0.000 0.383 0.617
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.383 0.617
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.383 0.617
L51 Erythema multiforme
0.000 0.383 0.616
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.385 0.615
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.388 0.611
C82.2 Large cell, follicular
0.000 0.389 0.611
M35.8 Other specified systemic involvement of connective tissue
0.000 0.390 0.610
H61.0 Perichondritis of external ear
0.000 0.391 0.609
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.391 0.609
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.392 0.608
H30.9 Chorioretinal inflammation, unspecified
0.000 0.392 0.608
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.394 0.606
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.394 0.606
H44.0 Purulent endophthalmitis
0.000 0.395 0.605
M60.0 Infective myositis
0.000 0.395 0.605
H91.3 Deaf mutism, not elsewhere classified
0.000 0.395 0.605
J38.5 Laryngeal spasm
0.000 0.395 0.604
H61.2 Impacted cerumen
0.000 0.396 0.604
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.397 0.603
K74.5 Biliary cirrhosis, unspecified
0.000 0.397 0.603
Chapter II Neoplasms
0.000 0.397 0.603
L52 Erythema nodosum
0.000 0.398 0.602
E13.8 With unspecified complications
0.000 0.398 0.602
E13.7 With multiple complications
0.000 0.398 0.602
E13.6 With other specified complications
0.000 0.398 0.602
E13.5 With peripheral circulatory complications
0.000 0.398 0.602
E13.4 With neurological complications
0.000 0.398 0.602
E13.3 With ophthalmic complications
0.000 0.398 0.602
E13.2 With renal complications
0.000 0.398 0.602
E13.1 With ketoacidosis
0.000 0.398 0.602
E13.0 With coma
0.000 0.398 0.602
M65.1 Other infective (teno)synovitis
0.000 0.398 0.602
K51.5 Mucosal proctocolitis
0.601 0.398 0.001
E06.9 Thyroiditis, unspecified
0.000 0.399 0.600
H40.5 Glaucoma secondary to other eye disorders
0.000 0.400 0.600
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.401 0.599
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.401 0.599
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.401 0.599
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.401 0.599
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.401 0.599
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.401 0.599
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.401 0.599
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.401 0.599
C82.3 Follicular lymphoma grade IIIa
0.000 0.401 0.599
M00-M03 Infectious arthropathies
0.000 0.401 0.599
M35.7 Hypermobility syndrome
0.000 0.402 0.598
M35.2 Behcet's disease
0.000 0.403 0.597
M25.47 Effusion of joint (Ankle and foot)
0.000 0.403 0.597
K71 Toxic liver disease
0.000 0.405 0.595
J32.3 Chronic sphenoidal sinusitis
0.000 0.406 0.594
C95 Leukaemia of unspecified cell type
0.000 0.408 0.592
H60.9 Otitis externa, unspecified
0.000 0.408 0.592
M34.1 CR(E)ST syndrome
0.000 0.410 0.590
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.410 0.590
J37.1 Chronic laryngotracheitis
0.000 0.411 0.589
D86 Sarcoidosis
0.588 0.411 0.001
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.412 0.588
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.412 0.587
H27.1 Dislocation of lens
0.000 0.413 0.587
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.413 0.586
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.413 0.586
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.413 0.586
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.413 0.586
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.413 0.586
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.413 0.586
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.413 0.586
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.413 0.586
C91.1 Chronic lymphocytic leukaemia
0.000 0.418 0.582
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.418 0.582
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.419 0.581
H95.1 Other disorders following mastoidectomy
0.000 0.419 0.581
M34.8 Other forms of systemic sclerosis
0.000 0.419 0.581
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.419 0.581
H60.8 Other otitis externa
0.000 0.421 0.578
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.422 0.578
J38.7 Other diseases of larynx
0.000 0.423 0.577
K91.3 Postoperative intestinal obstruction
0.000 0.423 0.577
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.424 0.576
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.425 0.575
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.425 0.575
C82.4 Follicular lymphoma grade IIIb
0.000 0.425 0.575
H92 Otalgia and effusion of ear
0.000 0.425 0.575
M25.9 Joint disorder, unspecified
0.000 0.427 0.573
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.429 0.571
E06.1 Subacute thyroiditis
0.000 0.429 0.571
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.430 0.570
L13 Other bullous disorders
0.000 0.430 0.570
M25.3 Other instability of joint
0.000 0.432 0.568
J35 Chronic diseases of tonsils and adenoids
0.000 0.433 0.567
L42 Pityriasis rosea
0.000 0.436 0.564
H42 Glaucoma in diseases classified elsewhere
0.000 0.436 0.564
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.437 0.563
J41.0 Simple chronic bronchitis
0.000 0.437 0.563
H91.8 Other specified hearing loss
0.000 0.437 0.563
E07.1 Dyshormogenetic goitre
0.000 0.437 0.562
E07.0 Hypersecretion of calcitonin
0.000 0.437 0.562
H34.1 Central retinal artery occlusion
0.000 0.439 0.561
L40.8 Other psoriasis
0.000 0.439 0.561
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.439 0.561
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.440 0.560
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.441 0.559
E05.9 Thyrotoxicosis, unspecified
0.000 0.441 0.559
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.442 0.558
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.443 0.556
J42 Unspecified chronic bronchitis
0.000 0.444 0.556
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.000 0.444 0.556
C82.6 Cutaneous follicle centre lymphoma
0.000 0.444 0.556
C82.5 Diffuse follicle centre lymphoma
0.000 0.444 0.556
D86.9 Sarcoidosis, unspecified
0.554 0.446 0.000
M33 Dermatopolymyositis
0.000 0.447 0.553
J45.1 Nonallergic asthma
0.000 0.447 0.553
M31.1 Thrombotic microangiopathy
0.000 0.447 0.552
C45 Mesothelioma
0.000 0.448 0.552
H44.1 Other endophthalmitis
0.000 0.449 0.551

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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