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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9393691
log Bayes Factor = 48.116
Chromosome 6   position 26,272,829  (GRCh37) Explore rs9393691 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.010 0.990
E10-E14 Diabetes mellitus
0.000 0.010 0.990
E10 Insulin-dependent diabetes mellitus
0.000 0.014 0.986
E11.2 With renal complications
0.000 0.036 0.964
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.043 0.957
E83 Disorders of mineral metabolism
0.000 0.048 0.952
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.055 0.945
E70-E90 Metabolic disorders
0.000 0.058 0.942
E16 Other disorders of pancreatic internal secretion
0.000 0.063 0.937
E16.2 Hypoglycaemia, unspecified
0.000 0.068 0.932
E10.0 With coma
0.000 0.084 0.916
I10 Essential (primary) hypertension
0.000 0.094 0.906
E11.5 With peripheral circulatory complications
0.000 0.094 0.906
E10.5 With peripheral circulatory complications
0.000 0.098 0.902
E11.3 With ophthalmic complications
0.000 0.103 0.897
E10.3 With ophthalmic complications
0.000 0.111 0.889
E11.4 With neurological complications
0.000 0.122 0.878
E40-E46 Malnutrition
0.000 0.133 0.867
E10.1 With ketoacidosis
0.000 0.140 0.860
E11.9 Without complications
0.000 0.142 0.858
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.184 0.816
E88 Other metabolic disorders
0.000 0.197 0.803
E46 Unspecified protein-energy malnutrition
0.000 0.198 0.802
E11.6 With other specified complications
0.000 0.212 0.788
E10.8 With unspecified complications
0.000 0.228 0.772
E73 Lactose intolerance
0.000 0.248 0.752
E11.1 With ketoacidosis
0.000 0.254 0.746
E10.2 With renal complications
0.000 0.261 0.739
E84 Cystic fibrosis
0.000 0.266 0.734
E14 Unspecified diabetes mellitus
0.000 0.270 0.730
E11.0 With coma
0.000 0.272 0.728
E10.9 Without complications
0.000 0.277 0.723
E80.4 Gilbert's syndrome
0.000 0.280 0.720
E11.7 With multiple complications
0.000 0.290 0.710
E12 Malnutrition-related diabetes mellitus
0.000 0.290 0.710
E10.7 With multiple complications
0.000 0.293 0.707
E79 Disorders of purine and pyrimidine metabolism
0.000 0.304 0.696
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.317 0.683
E83.8 Other disorders of mineral metabolism
0.000 0.317 0.683
E83.2 Disorders of zinc metabolism
0.000 0.317 0.683
E83.0 Disorders of copper metabolism
0.000 0.317 0.683
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.317 0.683
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.320 0.680
E15 Nondiabetic hypoglycaemic coma
0.000 0.322 0.678
E88.8 Other specified metabolic disorders
0.000 0.323 0.677
E10.4 With neurological complications
0.000 0.325 0.675
E76 Disorders of glycosaminoglycan metabolism
0.000 0.325 0.675
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.325 0.675
E70 Disorders of aromatic amino-acid metabolism
0.000 0.325 0.675
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.325 0.675
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.328 0.672
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.328 0.672
E16.4 Abnormal secretion of gastrin
0.000 0.328 0.672
E16.3 Increased secretion of glucagon
0.000 0.328 0.672
E83.3 Disorders of phosphorus metabolism
0.000 0.336 0.664
E14.3 With ophthalmic complications
0.000 0.344 0.656
E16.1 Other hypoglycaemia
0.000 0.346 0.653
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.348 0.652
E13 Other specified diabetes mellitus
0.000 0.350 0.650
E77 Disorders of glycoprotein metabolism
0.000 0.359 0.641
E80.2 Other porphyria
0.000 0.363 0.637
E10.6 With other specified complications
0.000 0.372 0.627
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.378 0.621
E45 Retarded development following protein-energy malnutrition
0.000 0.378 0.621
E43 Unspecified severe protein-energy malnutrition
0.000 0.378 0.621
E42 Marasmic kwashiorkor
0.000 0.378 0.621
E41 Nutritional marasmus
0.000 0.378 0.621
E40 Kwashiorkor
0.000 0.378 0.621
E73.9 Lactose intolerance, unspecified
0.000 0.383 0.617
E72 Other disorders of amino-acid metabolism
0.000 0.395 0.605
E14.6 With other specified complications
0.000 0.401 0.599
E74 Other disorders of carbohydrate metabolism
0.000 0.401 0.599
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.410 0.590
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.415 0.585
E80.5 Crigler-Najjar syndrome
0.000 0.415 0.585
E80.3 Defects of catalase and peroxydase
0.000 0.415 0.585
E80.1 Porphyria cutanea tarda
0.000 0.415 0.585
E80.0 Hereditary erythropoietic porphyria
0.000 0.415 0.585
E84.9 Cystic fibrosis, unspecified
0.000 0.415 0.585
E83.4 Disorders of magnesium metabolism
0.000 0.421 0.579
E88.3 Tumour lysis syndrome
0.000 0.424 0.575
E88.9 Metabolic disorder, unspecified
0.000 0.433 0.567
E65-E68 Obesity and other hyperalimentation
0.000 0.442 0.558
E14.5 With peripheral circulatory complications
0.000 0.449 0.551
E73.8 Other lactose intolerance
0.000 0.460 0.539
E73.1 Secondary lactase deficiency
0.000 0.460 0.539
E73.0 Congenital lactase deficiency
0.000 0.460 0.539
E80.6 Other disorders of bilirubin metabolism
0.000 0.461 0.539
E14.1 With ketoacidosis
0.000 0.468 0.532
E14.8 With unspecified complications
0.000 0.474 0.526
E84.8 Cystic fibrosis with other manifestations
0.000 0.474 0.526
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.474 0.526
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.474 0.526
E88.2 Lipomatosis, not elsewhere classified
0.000 0.474 0.526
E14.7 With multiple complications
0.000 0.477 0.523
E14.0 With coma
0.000 0.477 0.523
E11.8 With unspecified complications
0.000 0.480 0.519
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.480 0.519
E12.9 Without complications
0.000 0.491 0.509
E12.8 With unspecified complications
0.000 0.491 0.509
E12.7 With multiple complications
0.000 0.491 0.509
E12.6 With other specified complications
0.000 0.491 0.509
E12.5 With peripheral circulatory complications
0.000 0.491 0.509
E12.4 With neurological complications
0.000 0.491 0.509
E12.3 With ophthalmic complications
0.000 0.491 0.509
E12.2 With renal complications
0.000 0.491 0.509
E12.1 With ketoacidosis
0.000 0.491 0.509
E12.0 With coma
0.000 0.491 0.509
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.501 0.499
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.501 0.499
E79.1 Lesch-Nyhan syndrome
0.000 0.501 0.499
E75.5 Other lipid storage disorders
0.000 0.507 0.493
E14.4 With neurological complications
0.000 0.509 0.491
E75.6 Lipid storage disorder, unspecified
0.000 0.512 0.488
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.512 0.488
E75.3 Sphingolipidosis, unspecified
0.000 0.512 0.488
E75.2 Other sphingolipidosis
0.000 0.512 0.488
E75.1 Other gangliosidosis
0.000 0.512 0.488
E75.0 GM2 gangliosidosis
0.000 0.512 0.488
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.516 0.484
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.516 0.484
E70.3 Albinism
0.000 0.516 0.484
E70.2 Disorders of tyrosine metabolism
0.000 0.516 0.484
E70.1 Other hyperphenylalaninaemias
0.000 0.516 0.484
E70.0 Classical phenylketonuria
0.000 0.516 0.484
E71.3 Disorders of fatty-acid metabolism
0.000 0.516 0.484
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.516 0.484
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.516 0.484
E71.0 Maple-syrup-urine disease
0.000 0.516 0.484
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.516 0.484
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.516 0.484
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.516 0.484
E76.2 Other mucopolysaccharidoses
0.000 0.516 0.484
E76.1 Mucopolysaccharidosis, type II
0.000 0.516 0.484
E76.0 Mucopolysaccharidosis, type I
0.000 0.516 0.484
E13.3 With ophthalmic complications
0.000 0.529 0.471
E13.8 With unspecified complications
0.000 0.534 0.466
E13.7 With multiple complications
0.000 0.534 0.466
E13.6 With other specified complications
0.000 0.534 0.466
E13.5 With peripheral circulatory complications
0.000 0.534 0.466
E13.4 With neurological complications
0.000 0.534 0.466
E13.2 With renal complications
0.000 0.534 0.466
E13.1 With ketoacidosis
0.000 0.534 0.466
E13.0 With coma
0.000 0.534 0.466
E65 Localised adiposity
0.000 0.537 0.463
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.540 0.460
E77.1 Defects in glycoprotein degradation
0.000 0.540 0.460
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.540 0.460
E44.1 Mild protein-energy malnutrition
0.000 0.554 0.446
E44.0 Moderate protein-energy malnutrition
0.000 0.554 0.446
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.566 0.434
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.566 0.434
E72.5 Disorders of glycine metabolism
0.000 0.566 0.434
E72.4 Disorders of ornithine metabolism
0.000 0.566 0.434
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.566 0.434
E72.2 Disorders of urea cycle metabolism
0.000 0.566 0.434
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.566 0.434
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.570 0.429
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.570 0.429
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.570 0.429
E74.2 Disorders of galactose metabolism
0.000 0.570 0.429
E74.1 Disorders of fructose metabolism
0.000 0.570 0.429
E77.8 Other disorders of glycoprotein metabolism
0.000 0.574 0.426
E74.0 Glycogen storage disease
0.000 0.586 0.414
E14.2 Withrenal complications
0.000 0.587 0.413
E67 Other hyperalimentation
0.000 0.600 0.400
E68 Sequelae of hyperalimentation
0.000 0.600 0.400
E13.9 Without complications
0.000 0.601 0.398
E83.5 Disorders of calcium metabolism
0.000 0.606 0.394
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.626 0.374
E72.0 Disorders of amino-acid transport
0.000 0.636 0.363
E85 Amyloidosis
0.001 0.657 0.343
K90 Intestinal malabsorption
0.000 0.696 0.304
E67.8 Other specified hyperalimentation
0.000 0.713 0.287
E67.3 Hypervitaminosis D
0.000 0.713 0.287
E67.2 Megavitamin-B6 syndrome
0.000 0.713 0.287
E67.1 Hypercarotenaemia
0.000 0.713 0.287
E67.0 Hypervitaminosis A
0.000 0.713 0.287
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.717 0.283
E00-E07 Disorders of thyroid gland
0.000 0.718 0.282
E85.8 Other amyloidosis
0.001 0.746 0.254
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.754 0.246
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.754 0.246
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.754 0.246
E50-E64 Other nutritional deficiencies
0.001 0.755 0.244
E03 Other hypothyroidism
0.000 0.757 0.243
E89.4 Postprocedural ovarian failure
0.000 0.759 0.241
K90.3 Pancreatic steatorrhoea
0.000 0.782 0.218
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.782 0.218
K90.1 Tropical sprue
0.000 0.782 0.218
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.783 0.217
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.785 0.215
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.789 0.211
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.797 0.203
E89.1 Postprocedural hypoinsulinaemia
0.000 0.797 0.203
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.798 0.202
E00 Congenital iodine-deficiency syndrome
0.000 0.798 0.202
K90.9 Intestinal malabsorption, unspecified
0.000 0.801 0.199
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.806 0.194
I10-I15 Hypertensive diseases
0.000 0.809 0.191
E85.4 Organ-limited amyloidosis
0.001 0.811 0.188
K90.8 Other intestinal malabsorption
0.000 0.814 0.186
E56 Other vitamin deficiencies
0.001 0.814 0.185
E89.5 Postprocedural testicular hypofunction
0.000 0.815 0.184
E03.8 Other specified hypothyroidism
0.000 0.819 0.181
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.819 0.180
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.820 0.180
E85.9 Amyloidosis, unspecified
0.001 0.823 0.177
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.824 0.175
E63 Other nutritional deficiencies
0.001 0.824 0.175
E50 Vitamin A deficiency
0.001 0.824 0.175
E60 Dietary zinc deficiency
0.001 0.824 0.175
E59 Dietary selenium deficiency
0.001 0.824 0.175
E54 Ascorbic acid deficiency
0.001 0.824 0.175
E52 Niacin deficiency [pellagra]
0.001 0.824 0.175
E03.5 Myxoedema coma
0.000 0.826 0.174
E03.4 Atrophy of thyroid (acquired)
0.000 0.826 0.174
E03.3 Postinfectious hypothyroidism
0.000 0.826 0.174
E03.1 Congenital hypothyroidism without goitre
0.000 0.826 0.174
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.827 0.173
E85.3 Secondary systemic amyloidosis
0.001 0.828 0.171
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.829 0.171
E05.9 Thyrotoxicosis, unspecified
0.000 0.830 0.170
E06 Thyroiditis
0.000 0.832 0.168
E03.9 Hypothyroidism, unspecified
0.000 0.833 0.167
E51 Thiamine deficiency
0.001 0.834 0.166
E58 Dietary calcium deficiency
0.001 0.836 0.163
E86 Volume depletion
0.000 0.836 0.164
E14.9 Without complications
0.000 0.842 0.158
E05.8 Other thyrotoxicosis
0.000 0.846 0.154
E89.3 Postprocedural hypopituitarism
0.000 0.847 0.153
I11 Hypertensive heart disease
0.000 0.852 0.148
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.855 0.145
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.855 0.145
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.855 0.145
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.855 0.145
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.855 0.145
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.855 0.145
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.855 0.145
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.855 0.145
E56.1 Deficiency of vitamin K
0.000 0.857 0.142
E89.2 Postprocedural hypoparathyroidism
0.000 0.860 0.139
E05.5 Thyroid crisis or storm
0.000 0.861 0.139
E05.4 Thyrotoxicosis factitia
0.000 0.861 0.139
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.861 0.139
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.861 0.139
I13 Hypertensive heart and renal disease
0.000 0.866 0.134
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.866 0.134
E56.9 Vitamin deficiency, unspecified
0.001 0.867 0.133
E56.8 Deficiency of other vitamins
0.001 0.867 0.133
E56.0 Deficiency of vitamin E
0.001 0.867 0.133
E06.3 Autoimmune thyroiditis
0.000 0.867 0.133
E07 Other disorders of thyroid
0.000 0.871 0.129
E53 Deficiency of other B group vitamins
0.000 0.873 0.127
E50.9 Vitamin A deficiency, unspecified
0.001 0.874 0.126
E50.8 Other manifestations of vitamin A deficiency
0.001 0.874 0.126
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.874 0.126
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.874 0.126
E50.5 Vitamin A deficiency with night blindness
0.001 0.874 0.126
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.874 0.126
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.874 0.126
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.874 0.126
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.874 0.126
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.874 0.126
E63.9 Nutritional deficiency, unspecified
0.001 0.874 0.126
E63.8 Other specified nutritional deficiencies
0.001 0.874 0.126
E63.1 Imbalance of constituents of food intake
0.001 0.874 0.126
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.874 0.126
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.874 0.126
E64.8 Sequelae of other nutritional deficiencies
0.001 0.874 0.126
E64.3 Sequelae of rickets
0.001 0.874 0.126
E64.2 Sequelae of vitamin C deficiency
0.001 0.874 0.126
E64.1 Sequelae of vitamin A deficiency
0.001 0.874 0.126
E64.0 Sequelae of protein-energy malnutrition
0.001 0.874 0.126
I15 Secondary hypertension
0.000 0.877 0.123
E06.4 Drug-induced thyroiditis
0.000 0.879 0.120
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.879 0.120
E06.0 Acute thyroiditis
0.000 0.879 0.120
E51.9 Thiamine deficiency, unspecified
0.001 0.881 0.119
E51.8 Other manifestations of thiamine deficiency
0.001 0.881 0.119
E51.1 Beriberi
0.001 0.881 0.119
E06.9 Thyroiditis, unspecified
0.000 0.886 0.114
E61 Deficiency of other nutrient elements
0.001 0.886 0.113
E51.2 Wernicke's encephalopathy
0.001 0.890 0.109
E55 Vitamin D deficiency
0.002 0.891 0.107
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.891 0.108
E06.5 Other chronic thyroiditis
0.000 0.895 0.105
E20-E35 Disorders of other endocrine glands
0.000 0.898 0.102
I15.9 Seconday hypertension, unspecified
0.000 0.901 0.099
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.904 0.096
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.904 0.096
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.904 0.096
E06.1 Subacute thyroiditis
0.000 0.906 0.094
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.907 0.093
E07.1 Dyshormogenetic goitre
0.000 0.907 0.092
E07.0 Hypersecretion of calcitonin
0.000 0.907 0.092
E53.1 Pyridoxine deficiency
0.000 0.909 0.091
E53.0 Riboflavin deficiency
0.000 0.909 0.091
I15.8 Other secondary hypertension
0.000 0.911 0.088
I15.2 Hypertension secondary to endocrine disorders
0.000 0.913 0.087
I15.0 Renovascular hypertension
0.000 0.916 0.084
E66 Obesity
0.000 0.916 0.084
E61.9 Deficiency of nutrient element, unspecified
0.001 0.918 0.081
E61.8 Deficiency of other specified nutrient elements
0.001 0.918 0.081
E61.7 Deficiency of multiple nutrient elements
0.001 0.918 0.081
E61.6 Vanadium deficiency
0.001 0.918 0.081
E61.5 Molybdenum deficiency
0.001 0.918 0.081
E61.4 Chromium deficiency
0.001 0.918 0.081
E61.3 Manganese deficiency
0.001 0.918 0.081
E61.0 Copper deficiency
0.001 0.918 0.081
E20 Hypoparathyroidism
0.000 0.918 0.082
E07.8 Other specified disorders of thyroid
0.000 0.918 0.081
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.921 0.079
E55.0 Rickets, active
0.001 0.922 0.077
E53.9 Vitamin B deficiency, unspecified
0.001 0.923 0.077
E25 Adrenogenital disorders
0.000 0.924 0.076
E29 Testicular dysfunction
0.000 0.924 0.076
E61.2 Magnesium deficiency
0.001 0.927 0.073
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.927 0.073
E32 Diseases of thymus
0.000 0.927 0.073
E31 Polyglandular dysfunction
0.000 0.927 0.073
E30 Disorders of puberty, not elsewhere classified
0.000 0.927 0.073
E26 Hyperaldosteronism
0.000 0.929 0.071
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.930 0.070
E20.9 Hypoparathyroidism, unspecified
0.000 0.932 0.068
E34 Other endocrine disorders
0.000 0.932 0.067
E53.8 Deficiency of other specified B group vitamins
0.000 0.934 0.066
E78.4 Other hyperlipidaemia
0.000 0.934 0.066
E89.0 Postprocedural hypothyroidism
0.000 0.935 0.065
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.935 0.065
E27 Other disorders of adrenal gland
0.000 0.935 0.065
E78.1 Pure hyperglyceridaemia
0.000 0.935 0.065
I15.1 Hypertension secondary to other renal disorders
0.000 0.936 0.064
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.936 0.064
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.937 0.063
E66.1 Drug-induced obesity
0.000 0.940 0.060
E29.1 Testicular hypofunction
0.000 0.940 0.060
I83 Varicose veins of lower extremities
0.000 0.941 0.059
E20.8 Other hypoparathyroidism
0.000 0.941 0.059
E20.1 Pseudohypoparathyroidism
0.000 0.941 0.059
E20.0 Idiopathic hypoparathyroidism
0.000 0.941 0.059
E78.6 Lipoprotein deficiency
0.000 0.942 0.058
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.942 0.057
R40.0 Somnolence
0.058 0.942 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.945 0.055
E78.3 Hyperchylomicronaemia
0.000 0.945 0.055
E25.9 Adrenogenital disorder, unspecified
0.000 0.945 0.055
E25.8 Other adrenogenital disorders
0.000 0.945 0.055
E29.8 Other testicular dysfunction
0.000 0.945 0.055
E29.0 Testicular hyperfunction
0.000 0.945 0.055
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.945 0.055
E34.9 Endocrine disorder, unspecified
0.000 0.945 0.055
E26.9 Hyperaldosteronism, unspecified
0.000 0.946 0.054
E30.9 Disorder of puberty, unspecified
0.000 0.947 0.053
E30.8 Other disorders of puberty
0.000 0.947 0.053
E30.1 Precocious puberty
0.000 0.947 0.053
E30.0 Delayed puberty
0.000 0.947 0.053
E31.9 Polyglandular dysfunction, unspecified
0.000 0.947 0.053
E31.8 Other polyglandular dysfunction
0.000 0.947 0.053
E31.1 Polyglandular hyperfunction
0.000 0.947 0.053
E31.0 Autoimmune polyglandular failure
0.000 0.947 0.053
E32.9 Disease of thymus, unspecified
0.000 0.947 0.053
E32.8 Other diseases of thymus
0.000 0.947 0.053
E32.1 Abscess of thymus
0.000 0.947 0.053
E32.0 Persistent hyperplasia of thymus
0.000 0.947 0.053
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.947 0.053
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.947 0.053
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.947 0.053
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.948 0.052
I12 Hypertensive renal disease
0.000 0.948 0.052
E29.9 Testicular dysfunction, unspecified
0.000 0.949 0.051
E26.8 Other hyperaldosteronism
0.000 0.949 0.051
E26.1 Secondary hyperaldosteronism
0.000 0.949 0.051
E27.1 Primary adrenocortical insufficiency
0.000 0.949 0.051
E87.5 Hyperkalaemia
0.000 0.950 0.050
E34.8 Other specified endocrine disorders
0.000 0.951 0.049
E21.2 Other hyperparathyroidism
0.000 0.951 0.049
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.951 0.049
E34.5 Androgen resistance syndrome
0.000 0.951 0.048
E34.4 Constitutional tall stature
0.000 0.951 0.048
E34.3 Short stature, not elsewhere classified
0.000 0.951 0.048
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.951 0.048
E34.1 Other hypersecretion of intestinal hormones
0.000 0.951 0.048
E24 Cushing's syndrome
0.000 0.952 0.048
E28 Ovarian dysfunction
0.000 0.952 0.048
E27.5 Adrenomedullary hyperfunction
0.000 0.953 0.047
E27.0 Other adrenocortical overactivity
0.000 0.953 0.047
E26.0 Primary hyperaldosteronism
0.000 0.954 0.046
E27.2 Addisonian crisis
0.000 0.954 0.046
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.954 0.046
E22 Hyperfunction of pituitary gland
0.000 0.954 0.045
E21.4 Other specified disorders of parathyroid gland
0.000 0.955 0.045
E07.9 Disorder of thyroid, unspecified
0.000 0.956 0.044
E27.9 Disorder of adrenal gland, unspecified
0.000 0.958 0.042
E27.8 Other specified disorders of adrenal gland
0.000 0.959 0.041
E78.8 Other disorders of lipoprotein metabolism
0.000 0.959 0.041
E61.1 Iron deficiency
0.001 0.960 0.040
E87.3 Alkalosis
0.000 0.960 0.040
E87.4 Mixed disorder of acid-base balance
0.000 0.961 0.039
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.963 0.037
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.963 0.037
E78.2 Mixed hyperlipidaemia
0.000 0.963 0.037
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.963 0.037
E22.1 Hyperprolactinaemia
0.000 0.963 0.036
E66.0 Obesity due to excess calories
0.000 0.964 0.036
E87.0 Hyperosmolality and hypernatraemia
0.000 0.964 0.036
E24.2 Drug-induced Cushing's syndrome
0.000 0.964 0.036
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.965 0.035
E24.3 Ectopic ACTH syndrome
0.000 0.965 0.035
E24.1 Nelson's syndrome
0.000 0.965 0.035
E28.9 Ovarian dysfunction, unspecified
0.000 0.965 0.034
E28.8 Other ovarian dysfunction
0.000 0.965 0.034
E28.1 Androgen excess
0.000 0.965 0.034
E28.0 Oestrogen excess
0.000 0.965 0.034
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.967 0.033
E22.8 Other hyperfunction of pituitary gland
0.000 0.967 0.033
E21.0 Primary hyperparathyroidism
0.000 0.967 0.033
E28.3 Primary ovarian failure
0.000 0.968 0.031
E23 Hypofunction and other disorders of pituitary gland
0.000 0.969 0.031
E24.0 Pituitary-dependent Cushing's disease
0.000 0.969 0.031
E34.0 Carcinoid syndrome
0.000 0.969 0.030
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.969 0.030
E24.8 Other Cushing's syndrome
0.000 0.971 0.029
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.971 0.029
D45 Polycythaemia vera
0.000 0.971 0.029
E22.0 Acromegaly and pituitary gigantism
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.975 0.025
E21.3 Hyperparathyroidism, unspecified
0.000 0.975 0.025
E24.9 Cushing's syndrome, unspecified
0.000 0.975 0.025
E04 Other non-toxic goitre
0.000 0.976 0.024
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.977 0.023
E23.1 Drug-induced hypopituitarism
0.000 0.977 0.023
E23.7 Disorder of pituitary gland, unspecified
0.000 0.978 0.021
I12.9 Hypertensive renal disease without renal failure
0.000 0.978 0.021
E23.2 Diabetes insipidus
0.000 0.980 0.020
E23.6 Other disorders of pituitary gland
0.000 0.981 0.018
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.018
E04.8 Other specified non-toxic goitre
0.000 0.982 0.017
E66.8 Other obesity
0.000 0.984 0.016
E28.2 Polycystic ovarian syndrome
0.000 0.984 0.016
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.984 0.016
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.985 0.015
D46 Myelodysplastic syndromes
0.000 0.985 0.015
D39.1 Ovary
0.000 0.986 0.014
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.986 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.013
E04.0 Non-toxic diffuse goitre
0.000 0.986 0.013
D86.9 Sarcoidosis, unspecified
0.000 0.987 0.013
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.987 0.013
D46.4 Refractory anaemia, unspecified
0.000 0.987 0.013
L40.5 Arthropathic psoriasis
0.013 0.987 0.000
Z43.1 Attention to gastrostomy
0.000 0.987 0.013
D86 Sarcoidosis
0.000 0.987 0.013
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.987 0.013
D44.3 Pituitary gland
0.000 0.988 0.012
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.988 0.012
D86.0 Sarcoidosis of lung
0.000 0.988 0.012
D75.1 Secondary polycythaemia
0.000 0.988 0.012
D37.7 Other digestive organs
0.000 0.988 0.012
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.988 0.011
D37.3 Appendix
0.000 0.989 0.011
D39.7 Other female genital organs
0.000 0.989 0.011
D44.7 Aortic body and other paraganglia
0.000 0.989 0.011
D44.0 Thyroid gland
0.000 0.989 0.011
R40 Somnolence, stupor and coma
0.011 0.989 0.000
D46.1 Refractory anaemia with sideroblasts
0.000 0.989 0.011
D46.2 Refractory anaemia with excess of blasts
0.000 0.989 0.011
K70.9 Alcoholic liver disease, unspecified
0.000 0.989 0.011
E55.9 Vitamin D deficiency, unspecified
0.003 0.989 0.008
D39.0 Uterus
0.000 0.989 0.011
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.989 0.011
D39.9 Female genital organ, unspecified
0.000 0.989 0.011
D39.2 Placenta
0.000 0.989 0.011
D46.7 Other myelodysplastic syndromes
0.000 0.989 0.011
D86.8 Sarcoidosis of other and combined sites
0.000 0.989 0.011
D37.6 Liver, gallbladder and bile ducts
0.000 0.989 0.011
H57.9 Disorder of eye and adnexa, unspecified
0.011 0.989 0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.989 0.011
D46.5 Refractory anaemia with multi-lineage dysplasia
0.000 0.989 0.011
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.989 0.011
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.989 0.011
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.989 0.011
H57.8 Other specified disorders of eye and adnexa
0.011 0.989 0.000
D37.4 Colon
0.000 0.989 0.011
D44.6 Carotid body
0.000 0.989 0.010
H57 Other disorders of eye and adnexa
0.011 0.989 0.000
D37.1 Stomach
0.000 0.990 0.010
E04.9 Non-toxic goitre, unspecified
0.000 0.990 0.010
D44.5 Pineal gland
0.000 0.990 0.010
D44.2 Parathyroid gland
0.000 0.990 0.010
L40.0 Psoriasis vulgaris
0.010 0.990 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.990 0.010
L40 Psoriasis
0.010 0.990 0.000
K70.0 Alcoholic fatty liver
0.000 0.990 0.010
D86.1 Sarcoidosis of lymph nodes
0.000 0.990 0.010
D37.9 Digestive organ, unspecified
0.000 0.990 0.010

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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