TreeWAS – Variant ID: rs9265549

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
M35 Other systemic involvement of connective tissue	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
J33.9 Nasal polyp, unspecified	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
M35.3 Polymyalgia rheumatica	1.000	0.000	0.000
M35.0 Sicca syndrome [Sjogren]	1.000	0.000	0.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
J33 Nasal polyp	0.999	0.001	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.997	0.003	0.000
E83.1 Disorders of iron metabolism	0.000	0.004	0.996
Chapter VIII Diseases of the ear and mastoid process	0.996	0.004	0.000
H60-H62 Diseases of external ear	0.994	0.006	0.000
E03 Other hypothyroidism	0.994	0.006	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.007	0.993
H25-H28 Disorders of lens	0.993	0.007	0.000
E03.9 Hypothyroidism, unspecified	0.992	0.008	0.000
E14.9 Without complications	0.991	0.009	0.000
M05 Seropositive rheumatoid arthritis	0.990	0.010	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.989	0.011	0.000
E10.2 With renal complications	0.989	0.011	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.988	0.012	0.000
M65-M68 Disorders of synovium and tendon	0.987	0.013	0.000
H26 Other cataract	0.987	0.013	0.000
H61 Other disorders of external ear	0.987	0.013	0.000
H26.9 Cataract, unspecified	0.986	0.014	0.000
E10.4 With neurological complications	0.986	0.014	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.986	0.014	0.000
E06 Thyroiditis	0.986	0.014	0.000
E14.3 With ophthalmic complications	0.984	0.016	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.983	0.017	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.982	0.018	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.982	0.018	0.000
J33.0 Polyp of nasal cavity	0.981	0.019	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.980	0.020	0.000
L40 Psoriasis	0.001	0.022	0.977
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.977	0.023	0.000
H43-H45 Disorders of vitreous body and globe	0.975	0.025	0.000
M31 Other necrotising vasculopathies	0.973	0.027	0.000
E20-E35 Disorders of other endocrine glands	0.971	0.029	0.000
Chapter X Diseases of the respiratory system	0.962	0.038	0.000
J40-J47 Chronic lower respiratory diseases	0.962	0.038	0.000
M34 Systemic sclerosis	0.960	0.040	0.000
H43 Disorders of vitreous body	0.960	0.040	0.000
J47 Bronchiectasis	0.959	0.041	0.000
E11.3 With ophthalmic complications	0.955	0.045	0.000
E70-E90 Metabolic disorders	0.952	0.048	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.951	0.049	0.000
J33.8 Other polyp of sinus	0.950	0.050	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.947	0.053	0.000
H43.1 Vitreous haemorrhage	0.947	0.053	0.000
H61.2 Impacted cerumen	0.947	0.053	0.000
M31.6 Other giant cell arteritis	0.945	0.055	0.000
C83.3 Large cell (diffuse)	0.942	0.058	0.000
E27 Other disorders of adrenal gland	0.941	0.059	0.000
C83.0 Small cell (diffuse)	0.941	0.059	0.000
E10.5 With peripheral circulatory complications	0.939	0.061	0.000
J45 Asthma	0.939	0.061	0.000
M66 Spontaneous rupture of synovium and tendon	0.935	0.065	0.000
E27.1 Primary adrenocortical insufficiency	0.934	0.066	0.000
E89.0 Postprocedural hypothyroidism	0.932	0.068	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.930	0.070	0.000
E06.3 Autoimmune thyroiditis	0.929	0.071	0.000
J45.9 Asthma, unspecified	0.926	0.074	0.000
H60 Otitis externa	0.925	0.075	0.000
M24 Other specific joint derangements	0.924	0.076	0.000
H30 Chorioretinal inflammation	0.924	0.076	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.924	0.076	0.000
E11.0 With coma	0.922	0.078	0.000
M35.1 Other overlap syndromes	0.921	0.079	0.000
M10 Gout	0.918	0.082	0.000
K90 Intestinal malabsorption	0.918	0.082	0.000
H90-H95 Other disorders of ear	0.917	0.083	0.000
M15-M19 Arthrosis	0.915	0.085	0.000
M34.1 CR(E)ST syndrome	0.915	0.085	0.000
E14.8 With unspecified complications	0.914	0.086	0.000
E50-E64 Other nutritional deficiencies	0.913	0.087	0.000
J30-J39 Other diseases of upper respiratory tract	0.912	0.088	0.000
M18 Arthrosis of first carpometacarpal joint	0.911	0.089	0.000
M06.3 Rheumatoid nodule	0.905	0.095	0.000
E06.9 Thyroiditis, unspecified	0.904	0.096	0.000
E10.0 With coma	0.903	0.097	0.000
D68 Other coagulation defects	0.903	0.097	0.000
H27 Other disorders of lens	0.902	0.098	0.000
D80-D89 Certain disorders involving the immune mechanism	0.902	0.098	0.000
H90 Conductive and sensorineural hearing loss	0.899	0.101	0.000
M45 Ankylosing spondylitis	0.003	0.103	0.894
E89.3 Postprocedural hypopituitarism	0.895	0.105	0.000
C88 Malignant immunoproliferative diseases	0.893	0.107	0.000
L40.0 Psoriasis vulgaris	0.000	0.111	0.889
M80-M85 Disorders of bone density and structure	0.887	0.113	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.885	0.115	0.000
L40.5 Arthropathic psoriasis	0.000	0.115	0.885
D55-D59 Haemolytic anaemias	0.884	0.116	0.000
E21.0 Primary hyperparathyroidism	0.884	0.116	0.000
H61.1 Non-infective disorders of pinna	0.882	0.118	0.000
E14.1 With ketoacidosis	0.880	0.120	0.000
H61.0 Perichondritis of external ear	0.879	0.121	0.000
M67 Other disorders of synovium and tendon	0.875	0.125	0.000
M30 Polyarteritis nodosa and related conditions	0.874	0.126	0.000
H60.1 Cellulitis of external ear	0.873	0.127	0.000
E40-E46 Malnutrition	0.871	0.129	0.000
M65 Synovitis and tenosynovitis	0.869	0.131	0.000
M60-M63 Disorders of muscles	0.869	0.131	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.867	0.133	0.000
H90.2 Conductive hearing loss, unspecified	0.864	0.136	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.862	0.138	0.000
M66.2 Spontaneous rupture of extensor tendons	0.861	0.139	0.000
M35.7 Hypermobility syndrome	0.860	0.140	0.000
E14.2 Withrenal complications	0.859	0.141	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.858	0.142	0.000
H90.3 Sensorineural hearing loss, bilateral	0.858	0.142	0.000
K90.9 Intestinal malabsorption, unspecified	0.856	0.144	0.000
L40.8 Other psoriasis	0.001	0.144	0.855
M32 Systemic lupus erythematosus	0.852	0.148	0.000
H30.9 Chorioretinal inflammation, unspecified	0.850	0.150	0.000
M24.2 Disorder of ligament	0.848	0.152	0.000
M11 Other crystal arthropathies	0.847	0.153	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.001	0.154	0.845
E11.1 With ketoacidosis	0.843	0.157	0.000
M06.4 Inflammatory polyarthropathy	0.838	0.162	0.000
H27.8 Other specified disorders of lens	0.838	0.162	0.000
D86 Sarcoidosis	0.837	0.163	0.000
D69 Purpura and other haemorrhagic conditions	0.834	0.166	0.000
E05.8 Other thyrotoxicosis	0.831	0.169	0.000
H61.3 Acquired stenosis of external ear canal	0.828	0.172	0.000
C81 Hodgkin's disease	0.827	0.173	0.000
M67.1 Other contracture of tendon (sheath)	0.823	0.177	0.000
E11.5 With peripheral circulatory complications	0.822	0.178	0.000
E10.8 With unspecified complications	0.822	0.178	0.000
C85.1 B-cell lymphoma, unspecified	0.822	0.178	0.000
E11.6 With other specified complications	0.820	0.180	0.000
D86.9 Sarcoidosis, unspecified	0.820	0.180	0.000
M31.3 Wegener's granulomatosis	0.819	0.181	0.000
J45.1 Nonallergic asthma	0.818	0.182	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.818	0.182	0.000
E06.1 Subacute thyroiditis	0.818	0.182	0.000
C83.7 Burkitt's tumour	0.816	0.184	0.000
C91 Lymphoid leukaemia	0.816	0.184	0.000
M14 Arthropathies in other diseases classified elsewhere	0.813	0.187	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.812	0.188	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.812	0.188	0.000
E10.7 With multiple complications	0.811	0.189	0.000
H26.1 Traumatic cataract	0.810	0.190	0.000
E10.6 With other specified complications	0.809	0.191	0.000
E14.6 With other specified complications	0.809	0.191	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.808	0.192	0.000
E11.7 With multiple complications	0.807	0.193	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.807	0.193	0.000
L40-L45 Papulosquamous disorders	0.744	0.194	0.062
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.803	0.197	0.000
H53-H54 Visual disturbances and blindness	0.800	0.199	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.800	0.200	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.800	0.200	0.000
C94 Other leukaemias of specified cell type	0.799	0.201	0.000
E22 Hyperfunction of pituitary gland	0.799	0.201	0.000
M10.0 Idiopathic gout	0.798	0.202	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.797	0.203	0.000
M66.3 Spontaneous rupture of flexor tendons	0.796	0.204	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.795	0.205	0.000
E61 Deficiency of other nutrient elements	0.794	0.206	0.000
M35.2 Behcet's disease	0.793	0.207	0.000
M10.9 Gout, unspecified	0.792	0.208	0.000
Q50-Q56 Congenital malformations of genital organs	0.791	0.209	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.790	0.210	0.000
E89.2 Postprocedural hypoparathyroidism	0.790	0.210	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.788	0.212	0.000
D59 Acquired haemolytic anaemia	0.786	0.214	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.784	0.215	0.000
D68.0 Von Willebrand's disease	0.784	0.216	0.000
M24.0 Loose body in joint	0.784	0.216	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.784	0.216	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.783	0.217	0.000
E11.8 With unspecified complications	0.783	0.217	0.000
D68.9 Coagulation defect, unspecified	0.782	0.218	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.781	0.218	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.781	0.219	0.000
M08 Juvenile arthritis	0.778	0.222	0.000
E46 Unspecified protein-energy malnutrition	0.778	0.222	0.000
H31 Other disorders of choroid	0.776	0.224	0.000
E13 Other specified diabetes mellitus	0.776	0.224	0.000
E14.5 With peripheral circulatory complications	0.775	0.225	0.000
H43.8 Other disorders of vitreous body	0.774	0.226	0.000
M06.8 Other specified rheumatoid arthritis	0.774	0.226	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.773	0.227	0.000
M34.0 Progressive systemic sclerosis	0.772	0.228	0.000
M62 Other disorders of muscle	0.771	0.229	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.771	0.229	0.000
E55 Vitamin D deficiency	0.770	0.230	0.000
M15 Polyarthrosis	0.770	0.230	0.000
M84 Disorders of continuity of bone	0.770	0.230	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.769	0.231	0.000
H60.3 Other infective otitis externa	0.768	0.232	0.000
M82 Osteoporosis in diseases classified elsewhere	0.768	0.232	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.767	0.233	0.000
E89.1 Postprocedural hypoinsulinaemia	0.767	0.233	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.766	0.234	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.766	0.234	0.000
L40.1 Generalised pustular psoriasis	0.001	0.237	0.762
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.760	0.240	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.760	0.240	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.760	0.240	0.000
L43 Lichen planus	0.746	0.242	0.012
M24.1 Other articular cartilage disorders	0.756	0.244	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.756	0.244	0.000
M12 Other specific arthropathies	0.754	0.246	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.754	0.246	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.752	0.248	0.000
M24.26 Disorder of ligament (Lower leg)	0.751	0.249	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.750	0.249	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.750	0.250	0.000
M65.8 Other synovitis and tenosynovitis	0.750	0.250	0.000
M05.1 Rheumatoid lung disease	0.748	0.251	0.000
E21.4 Other specified disorders of parathyroid gland	0.748	0.252	0.000
D68.8 Other specified coagulation defects	0.748	0.252	0.000
M34.8 Other forms of systemic sclerosis	0.746	0.254	0.000
E74 Other disorders of carbohydrate metabolism	0.745	0.255	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.744	0.256	0.000
M65.1 Other infective (teno)synovitis	0.742	0.258	0.000
H61.8 Other specified disorders of external ear	0.741	0.258	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.741	0.259	0.000
M24.7 Protrusio acetabuli	0.741	0.259	0.000
J32 Chronic sinusitis	0.739	0.261	0.000
E16.1 Other hypoglycaemia	0.738	0.261	0.000
L43.9 Lichen planus, unspecified	0.736	0.264	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.736	0.264	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.736	0.264	0.000
J33.1 Polypoid sinus degeneration	0.735	0.265	0.000
H30.2 Posterior cyclitis	0.733	0.267	0.000
C83.1 Small cleaved cell (diffuse)	0.733	0.267	0.000
E21.3 Hyperparathyroidism, unspecified	0.731	0.269	0.000
M62.8 Other specified disorders of muscle	0.731	0.269	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.730	0.270	0.000
E79 Disorders of purine and pyrimidine metabolism	0.730	0.270	0.000
M05.8 Other seropositive rheumatoid arthritis	0.728	0.271	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.728	0.272	0.000
J41 Simple and mucopurulent chronic bronchitis	0.727	0.273	0.000
C81.9 Hodgkin's disease, unspecified	0.726	0.274	0.000
E51 Thiamine deficiency	0.725	0.274	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.724	0.276	0.000
H60.4 Cholesteatoma of external ear	0.723	0.277	0.000
H43.9 Disorder of vitreous body, unspecified	0.723	0.277	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.723	0.277	0.000
M06.34 Rheumatoid nodule (Hand)	0.722	0.278	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.002	0.278	0.720
L40.3 Pustulosis palmaris et plantaris	0.001	0.279	0.721
M25 Other joint disorders, not elsewhere classified	0.721	0.279	0.000
M24.9 Joint derangement, unspecified	0.720	0.280	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.720	0.280	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.720	0.280	0.000
D83 Common variable immunodeficiency	0.720	0.280	0.000
M80 Osteoporosis with pathological fracture	0.719	0.281	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.717	0.283	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.717	0.283	0.000
M35.5 Multifocal fibrosclerosis	0.717	0.283	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.0 With coma	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M21 Other acquired deformities of limbs	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H43.0 Vitreous prolapse	0.716	0.284	0.000
Q80-Q89 Other congenital malformations	0.716	0.284	0.000
M11.2 Other chondrocalcinosis	0.714	0.286	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.714	0.286	0.000
J44 Other chronic obstructive pulmonary disease	0.713	0.287	0.000
E03.5 Myxoedema coma	0.713	0.287	0.000
E03.4 Atrophy of thyroid (acquired)	0.713	0.287	0.000
E03.3 Postinfectious hypothyroidism	0.713	0.287	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.711	0.289	0.000
M31.7 Microscopic polyangiitis	0.711	0.289	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.710	0.290	0.000
M05.0 Felty's syndrome	0.710	0.290	0.000
C95 Leukaemia of unspecified cell type	0.710	0.290	0.000
E89.4 Postprocedural ovarian failure	0.710	0.290	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.708	0.292	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.708	0.292	0.000
E78.2 Mixed hyperlipidaemia	0.708	0.292	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.707	0.293	0.000
C85.0 Lymphosarcoma	0.707	0.293	0.000
E06.4 Drug-induced thyroiditis	0.707	0.293	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.707	0.293	0.000
E06.0 Acute thyroiditis	0.707	0.293	0.000
D82 Immunodeficiency associated with other major defects	0.705	0.295	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.705	0.295	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.704	0.295	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.705	0.295	0.000
M10.94 Gout, unspecified (Hand)	0.704	0.296	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.704	0.296	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.704	0.296	0.000
L43.8 Other lichen planus	0.699	0.297	0.004
C83.6 Undifferentiated (diffuse)	0.703	0.297	0.000
C83.5 Lymphoblastic (diffuse)	0.703	0.297	0.000
C83.4 Immunoblastic (diffuse)	0.703	0.297	0.000
C83.2 Mixed small and large cell (diffuse)	0.703	0.297	0.000
L40.2 Acrodermatitis continua	0.001	0.299	0.700
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.700	0.299	0.000
E06.5 Other chronic thyroiditis	0.699	0.300	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.699	0.301	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.697	0.303	0.000
M31.2 Lethal midline granuloma	0.697	0.303	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.697	0.303	0.000
E84 Cystic fibrosis	0.697	0.303	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.696	0.304	0.000
E32 Diseases of thymus	0.696	0.304	0.000
E30 Disorders of puberty, not elsewhere classified	0.696	0.304	0.000
E25 Adrenogenital disorders	0.696	0.304	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.696	0.304	0.000
D58 Other hereditary haemolytic anaemias	0.696	0.304	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.695	0.305	0.000
M84.0 Malunion of fracture	0.694	0.306	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.692	0.308	0.000
E24 Cushing's syndrome	0.691	0.309	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.691	0.309	0.000
M05.2 Rheumatoid vasculitis	0.691	0.309	0.000
D68.1 Hereditary factor XI deficiency	0.690	0.310	0.000
C93 Monocytic leukaemia	0.690	0.310	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.690	0.310	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.688	0.312	0.000
K90.8 Other intestinal malabsorption	0.688	0.312	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.687	0.313	0.000
E22.1 Hyperprolactinaemia	0.687	0.313	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.687	0.313	0.000
C91.5 Adult T-cell leukaemia	0.686	0.314	0.000
M31.8 Other specified necrotising vasculopathies	0.686	0.314	0.000
H26.2 Complicated cataract	0.686	0.314	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.002	0.314	0.684
M31.1 Thrombotic microangiopathy	0.686	0.314	0.000
E31 Polyglandular dysfunction	0.685	0.315	0.000
M66.0 Rupture of popliteal cyst	0.684	0.316	0.000
H26.4 After-cataract	0.684	0.316	0.000
Q35-Q37 Cleft lip and cleft palate	0.683	0.317	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.683	0.317	0.000
E77 Disorders of glycoprotein metabolism	0.683	0.317	0.000
E76 Disorders of glycosaminoglycan metabolism	0.683	0.317	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.683	0.317	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.683	0.317	0.000
M82.1 Osteoporosis in endocrine disorders	0.682	0.318	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.682	0.318	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.682	0.318	0.000
E89.5 Postprocedural testicular hypofunction	0.682	0.318	0.000
E83 Disorders of mineral metabolism	0.580	0.318	0.103
E61.1 Iron deficiency	0.681	0.319	0.000
D67 Hereditary factor IX deficiency	0.679	0.321	0.000
M24.23 Disorder of ligament (Forearm)	0.679	0.321	0.000
M24.21 Disorder of ligament (Shoulder region)	0.679	0.321	0.000
E03.1 Congenital hypothyroidism without goitre	0.677	0.323	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.676	0.324	0.000
H60.5 Acute otitis externa, non-infective	0.676	0.324	0.000
M25.9 Joint disorder, unspecified	0.676	0.324	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.675	0.324	0.000
D69.2 Other nonthrombocytopenic purpura	0.675	0.325	0.000
E27.5 Adrenomedullary hyperfunction	0.675	0.325	0.000
E27.0 Other adrenocortical overactivity	0.675	0.325	0.000
E70 Disorders of aromatic amino-acid metabolism	0.675	0.325	0.000
D86.8 Sarcoidosis of other and combined sites	0.674	0.326	0.000
C86 Other specified types of T/NK-cell lymphoma	0.673	0.327	0.000
H44 Disorders of globe	0.673	0.327	0.000
L50-L54 Urticaria and erythema	0.673	0.327	0.000
D69.5 Secondary thrombocytopenia	0.673	0.327	0.000
E22.0 Acromegaly and pituitary gigantism	0.673	0.327	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.672	0.328	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.670	0.330	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.670	0.330	0.000
M66.1 Rupture of synovium	0.670	0.330	0.000
M11.9 Crystal arthropathy, unspecified	0.670	0.330	0.000
E55.9 Vitamin D deficiency, unspecified	0.668	0.332	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.668	0.332	0.000
C94.4 Acute panmyelosis	0.668	0.332	0.000
Q85 Phakomatoses, not elsewhere classified	0.667	0.333	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.666	0.334	0.000
M84.4 Pathological fracture, not elsewhere classified	0.666	0.334	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.666	0.334	0.000
H43.2 Crystalline deposits in vitreous body	0.665	0.335	0.000
E72 Other disorders of amino-acid metabolism	0.664	0.336	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.664	0.336	0.000
M86-M90 Other osteopathies	0.664	0.336	0.000
H30.8 Other chorioretinal inflammations	0.662	0.337	0.000
H30.1 Disseminated chorioretinal inflammation	0.662	0.337	0.000
H30.0 Focal chorioretinal inflammation	0.662	0.337	0.000
H27.0 Aphakia	0.663	0.337	0.000
E26 Hyperaldosteronism	0.662	0.338	0.000
M31.0 Hypersensitivity angiitis	0.662	0.338	0.000
M24.01 Loose body in joint (Shoulder region)	0.661	0.339	0.000
M67.4 Ganglion	0.659	0.341	0.000
M10.4 Other secondary gout	0.658	0.341	0.000
M10.3 Gout due to impairment of renal function	0.658	0.341	0.000
M10.2 Drug-induced gout	0.658	0.341	0.000
M10.1 Lead-induced gout	0.658	0.341	0.000
K90.3 Pancreatic steatorrhoea	0.658	0.342	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.658	0.342	0.000
K90.1 Tropical sprue	0.658	0.342	0.000
M10.04 Idiopathic gout (Hand)	0.658	0.342	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.657	0.343	0.000
M65.0 Abscess of tendon sheath	0.657	0.343	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.656	0.344	0.000
Chapter I Certain infectious and parasitic diseases	0.656	0.344	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.655	0.344	0.000
E20 Hypoparathyroidism	0.655	0.345	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.655	0.345	0.000
E63 Other nutritional deficiencies	0.655	0.345	0.000
E50 Vitamin A deficiency	0.655	0.345	0.000
E60 Dietary zinc deficiency	0.655	0.345	0.000
E59 Dietary selenium deficiency	0.655	0.345	0.000
E54 Ascorbic acid deficiency	0.655	0.345	0.000
E52 Niacin deficiency [pellagra]	0.655	0.345	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.654	0.345	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.653	0.347	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.653	0.347	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.653	0.347	0.000
M24.5 Contracture of joint	0.653	0.347	0.000
D69.4 Other primary thrombocytopenia	0.651	0.348	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.651	0.349	0.000
H60.9 Otitis externa, unspecified	0.650	0.350	0.000
J95-J99 Other diseases of the respiratory system	0.650	0.350	0.000
D68.5 Primary Thrombophilia	0.649	0.350	0.000
L40.4 Guttate psoriasis	0.001	0.350	0.649
M06.39 Rheumatoid nodule (Site unspecified)	0.649	0.351	0.000
M06.38 Rheumatoid nodule (Other)	0.649	0.351	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.649	0.351	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.649	0.351	0.000
M06.33 Rheumatoid nodule (Forearm)	0.649	0.351	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.649	0.351	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.648	0.352	0.000
H26.3 Drug-induced cataract	0.648	0.352	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.648	0.352	0.000
M10.99 Gout, unspecified (Site unspecified)	0.647	0.353	0.000
D56 Thalassaemia	0.647	0.353	0.000
M30.0 Polyarteritis nodosa	0.647	0.353	0.000
H27.9 Disorder of lens, unspecified	0.647	0.353	0.000
D81 Combined immunodeficiencies	0.646	0.354	0.000
M34.9 Systemic sclerosis, unspecified	0.646	0.354	0.000
E78.4 Other hyperlipidaemia	0.645	0.355	0.000
D57 Sickle-cell disorders	0.645	0.355	0.000
M14.2 Diabetic arthropathy	0.645	0.355	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.645	0.355	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.002	0.357	0.641
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.002	0.357	0.641
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.002	0.357	0.641
M45.X4 Ankylosing spondylitis (Thoracic region)	0.002	0.357	0.641
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.002	0.357	0.641
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.002	0.357	0.641
Q85.0 Neurofibromatosis (nonmalignant)	0.643	0.357	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.643	0.357	0.000
J32.8 Other chronic sinusitis	0.642	0.358	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.642	0.358	0.000
M83 Adult osteomalacia	0.642	0.358	0.000
M10.96 Gout, unspecified (Lower leg)	0.642	0.358	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.641	0.359	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.640	0.360	0.000
C88.7 Other malignant immunoproliferative diseases	0.640	0.360	0.000
C88.3 Immunoproliferative small intestinal disease	0.640	0.360	0.000
C88.2 Gamma heavy chain disease	0.640	0.360	0.000
C88.1 Alpha heavy chain disease	0.640	0.360	0.000
E53 Deficiency of other B group vitamins	0.640	0.360	0.000
H26.0 Infantile, juvenile and presenile cataract	0.639	0.361	0.000
M84.04 Malunion of fracture (Hand)	0.639	0.361	0.000
Q55 Other congenital malformations of male genital organs	0.639	0.361	0.000
E14.4 With neurological complications	0.637	0.362	0.000
H53 Visual disturbances	0.637	0.363	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations