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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3115667
log Bayes Factor = 170.945
Chromosome 6   position 31,643,399  (GRCh37) Explore rs3115667 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40-L45 Papulosquamous disorders
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.000 1.000
H30-H36 Disorders of choroid and retina
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
M45 Ankylosing spondylitis
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.001 0.999
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.001 0.999
Chapter VII Diseases of the eye and adnexa
0.000 0.001 0.999
L43 Lichen planus
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
I22 Subsequent myocardial infarction
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
L43.9 Lichen planus, unspecified
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.002 0.998
M45-M49 Spondylopathies
0.000 0.002 0.998
E14.3 With ophthalmic complications
0.000 0.002 0.998
Chapter IX Diseases of the circulatory system
0.000 0.002 0.998
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.003 0.997
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.006 0.994
G35-G37 Demyelinating diseases of the central nervous system
0.990 0.008 0.003
E10.5 With peripheral circulatory complications
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
I21 Acute myocardial infarction
0.000 0.009 0.991
D64 Other anaemias
0.000 0.009 0.991
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.009 0.991
M35.3 Polymyalgia rheumatica
0.000 0.010 0.990
G37 Other demyelinating diseases of central nervous system
0.987 0.013 0.001
D60-D64 Aplastic and other anaemias
0.000 0.013 0.987
H43-H45 Disorders of vitreous body and globe
0.000 0.013 0.987
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.013 0.987
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.013 0.987
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.014 0.986
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.014 0.986
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.014 0.986
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.015 0.985
G37.9 Demyelinating disease of central nervous system, unspecified
0.984 0.016 0.000
M35 Other systemic involvement of connective tissue
0.000 0.016 0.984
H43 Disorders of vitreous body
0.000 0.017 0.983
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.018 0.982
M06.0 Seronegative rheumatoid arthritis
0.000 0.019 0.981
I10-I15 Hypertensive diseases
0.000 0.022 0.978
M20-M25 Other joint disorders
0.000 0.023 0.977
E05.9 Thyrotoxicosis, unspecified
0.000 0.023 0.977
E78.0 Pure hypercholesterolaemia
0.000 0.024 0.976
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.024 0.976
E70-E90 Metabolic disorders
0.000 0.025 0.975
E16 Other disorders of pancreatic internal secretion
0.000 0.025 0.975
I21.9 Acute myocardial infarction, unspecified
0.000 0.026 0.974
E06 Thyroiditis
0.000 0.026 0.974
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.027 0.973
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.027 0.973
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.031 0.969
I25.5 Ischaemic cardiomyopathy
0.000 0.032 0.968
E16.2 Hypoglycaemia, unspecified
0.000 0.033 0.967
E10.2 With renal complications
0.000 0.037 0.963
I12 Hypertensive renal disease
0.000 0.038 0.962
H34 Retinal vascular occlusions
0.000 0.040 0.960
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.042 0.958
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.042 0.958
I24 Other acute ischaemic heart diseases
0.000 0.042 0.958
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.045 0.955
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.045 0.955
E06.3 Autoimmune thyroiditis
0.000 0.048 0.952
I12.9 Hypertensive renal disease without renal failure
0.000 0.054 0.946
H43.8 Other disorders of vitreous body
0.000 0.058 0.942
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.060 0.940
M06.3 Rheumatoid nodule
0.000 0.064 0.936
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.067 0.933
E11.5 With peripheral circulatory complications
0.000 0.072 0.928
I20.0 Unstable angina
0.000 0.077 0.923
E78.2 Mixed hyperlipidaemia
0.000 0.078 0.922
E10.0 With coma
0.000 0.079 0.921
E10.8 With unspecified complications
0.000 0.084 0.916
E10.6 With other specified complications
0.000 0.087 0.913
H34.8 Other retinal vascular occlusions
0.000 0.088 0.912
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.910 0.090 0.000
L40.0 Psoriasis vulgaris
0.000 0.097 0.903
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.100 0.900
E11.1 With ketoacidosis
0.000 0.104 0.896
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.105 0.895
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.127 0.873
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.127 0.873
I15 Secondary hypertension
0.000 0.129 0.871
M34 Systemic sclerosis
0.000 0.131 0.869
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.132 0.868
L43.8 Other lichen planus
0.000 0.135 0.865
H43.1 Vitreous haemorrhage
0.000 0.139 0.861
L40.8 Other psoriasis
0.000 0.142 0.858
H30 Chorioretinal inflammation
0.000 0.143 0.857
H43.3 Other vitreous opacities
0.000 0.145 0.855
M35.7 Hypermobility syndrome
0.000 0.148 0.852
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.149 0.851
E78.8 Other disorders of lipoprotein metabolism
0.000 0.151 0.849
H20 Iridocyclitis
0.000 0.165 0.835
H43.2 Crystalline deposits in vitreous body
0.000 0.166 0.834
I05-I09 Chronic rheumatic heart diseases
0.000 0.174 0.826
H43.9 Disorder of vitreous body, unspecified
0.000 0.180 0.820
M06.34 Rheumatoid nodule (Hand)
0.000 0.181 0.819
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.181 0.819
M34.1 CR(E)ST syndrome
0.000 0.186 0.814
E11.2 With renal complications
0.000 0.188 0.812
G37.8 Other specified demyelinating diseases of central nervous system
0.811 0.189 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.193 0.807
E14.6 With other specified complications
0.000 0.198 0.802
H35 Other retinal disorders
0.000 0.198 0.802
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.199 0.801
E78.4 Other hyperlipidaemia
0.000 0.200 0.800
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.206 0.794
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.210 0.790
M14 Arthropathies in other diseases classified elsewhere
0.000 0.210 0.789
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.212 0.788
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.213 0.787
E14.5 With peripheral circulatory complications
0.000 0.215 0.785
E11.0 With coma
0.000 0.215 0.785
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.220 0.780
M35.1 Other overlap syndromes
0.000 0.221 0.779
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.222 0.778
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.226 0.774
I15.1 Hypertension secondary to other renal disorders
0.000 0.229 0.771
E11.4 With neurological complications
0.000 0.232 0.768
H35.8 Other specified retinal disorders
0.000 0.237 0.763
I12.0 Hypertensive renal disease with renal failure
0.000 0.240 0.760
E40-E46 Malnutrition
0.000 0.241 0.759
H20.9 Iridocyclitis, unspecified
0.000 0.241 0.759
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.241 0.759
I25.3 Aneurysm of heart
0.000 0.243 0.757
E74 Other disorders of carbohydrate metabolism
0.000 0.245 0.755
H30.9 Chorioretinal inflammation, unspecified
0.000 0.246 0.754
H34.2 Other retinal artery occlusions
0.000 0.247 0.753
E14.1 With ketoacidosis
0.000 0.250 0.750
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.252 0.748
M65-M68 Disorders of synovium and tendon
0.000 0.252 0.747
M49 Spondylopathies in diseases classified elsewhere
0.000 0.261 0.739
M30 Polyarteritis nodosa and related conditions
0.000 0.262 0.738
D50-D53 Nutritional anaemias
0.000 0.264 0.736
H35.4 Peripheral retinal degeneration
0.000 0.264 0.736
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.269 0.731
M12 Other specific arthropathies
0.000 0.269 0.730
M06.4 Inflammatory polyarthropathy
0.000 0.275 0.725
E13 Other specified diabetes mellitus
0.000 0.275 0.725
E06.5 Other chronic thyroiditis
0.000 0.276 0.724
I08 Multiple valve diseases
0.000 0.277 0.723
E06.9 Thyroiditis, unspecified
0.000 0.278 0.722
E11.6 With other specified complications
0.000 0.278 0.722
H15 Disorders of sclera
0.000 0.278 0.722
H34.9 Retinal vascular occlusion, unspecified
0.000 0.279 0.720
H34.1 Central retinal artery occlusion
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.283 0.717
L41 Parapsoriasis
0.000 0.283 0.717
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.717
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.283 0.717
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.283 0.717
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.283 0.717
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.283 0.717
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.283 0.717
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.283 0.717
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.283 0.717
L43.3 Subacute (active) lichen planus
0.000 0.283 0.716
L43.2 Lichenoid drug reaction
0.000 0.283 0.716
L43.1 Bullous lichen planus
0.000 0.283 0.716
L43.0 Hypertrophic lichen planus
0.000 0.283 0.716
M07.6 Other enteropathic arthropathies
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.716
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.716
M07.2 Psoriatic spondylitis
0.000 0.284 0.716
M07.1 Arthritis mutilans
0.000 0.284 0.716
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.000 0.284 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.284 0.716
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.284 0.716
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.284 0.716
M35.2 Behcet's disease
0.000 0.286 0.714
M65 Synovitis and tenosynovitis
0.000 0.286 0.714
G36 Other acute disseminated demyelination
0.709 0.288 0.002
I23 Certain current complications following acute myocardial infarction
0.000 0.288 0.711
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.289 0.711
D64.4 Congenital dyserythropoietic anaemia
0.000 0.289 0.711
D64.3 Other sideroblastic anaemias
0.000 0.289 0.711
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.289 0.711
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.289 0.711
D64.0 Hereditary sideroblastic anaemia
0.000 0.289 0.711
H20.0 Acute and subacute iridocyclitis
0.000 0.289 0.711
H33 Retinal detachments and breaks
0.000 0.291 0.709
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.291 0.709
G37.5 Concentric sclerosis [Balo]
0.707 0.292 0.001
G37.4 Subacute necrotising myelitis
0.707 0.292 0.001
G37.2 Central pontine myelinolysis
0.707 0.292 0.001
G37.1 Central demyelination of corpus callosum
0.707 0.292 0.001
G37.0 Diffuse sclerosis
0.707 0.292 0.001
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.292 0.708
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.292 0.708
H55-H59 Other disorders of eye and adnexa
0.000 0.293 0.707
M33 Dermatopolymyositis
0.000 0.293 0.707
E15 Nondiabetic hypoglycaemic coma
0.000 0.293 0.706
D61 Other aplastic anaemias
0.000 0.294 0.706
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.294 0.705
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.294 0.705
M35.5 Multifocal fibrosclerosis
0.000 0.294 0.705
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.294 0.705
I00-I02 Acute rheumatic fever
0.000 0.295 0.705
D62 Acute posthaemorrhagic anaemia
0.000 0.295 0.705
E78.6 Lipoprotein deficiency
0.000 0.295 0.704
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.297 0.703
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.297 0.703
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.297 0.703
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.297 0.703
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.297 0.703
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.297 0.703
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.299 0.700
E79 Disorders of purine and pyrimidine metabolism
0.000 0.300 0.700
E78.3 Hyperchylomicronaemia
0.000 0.300 0.699
E77 Disorders of glycoprotein metabolism
0.000 0.301 0.699
E76 Disorders of glycosaminoglycan metabolism
0.000 0.301 0.699
E72 Other disorders of amino-acid metabolism
0.000 0.301 0.699
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.301 0.699
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.301 0.699
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.301 0.699
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.301 0.699
E16.4 Abnormal secretion of gastrin
0.000 0.301 0.699
E16.3 Increased secretion of glucagon
0.000 0.301 0.699
E06.4 Drug-induced thyroiditis
0.000 0.301 0.699
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.301 0.699
E06.1 Subacute thyroiditis
0.000 0.301 0.699
E06.0 Acute thyroiditis
0.000 0.301 0.699
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.000 0.301 0.699
E70 Disorders of aromatic amino-acid metabolism
0.000 0.303 0.697
K90 Intestinal malabsorption
0.000 0.304 0.696
M14.6 Neuropathic arthropathy
0.000 0.307 0.693
E86 Volume depletion
0.000 0.309 0.691
H34.0 Transient retinal artery occlusion
0.000 0.312 0.688
I09 Other rheumatic heart diseases
0.000 0.312 0.688
I15.9 Seconday hypertension, unspecified
0.000 0.318 0.682
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.318 0.682
H43.0 Vitreous prolapse
0.000 0.318 0.682
Chapter VI Diseases of the nervous system
0.036 0.320 0.645
H33.2 Serous retinal detachment
0.000 0.323 0.677
L10-L14 Bullous disorders
0.000 0.325 0.675
H21 Other disorders of iris and ciliary body
0.000 0.325 0.675
E14.2 Withrenal complications
0.000 0.325 0.675
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.327 0.673
H20.8 Other iridocyclitis
0.000 0.327 0.673
E14.4 With neurological complications
0.000 0.328 0.671
I10 Essential (primary) hypertension
0.000 0.329 0.671
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.329 0.671
M06.38 Rheumatoid nodule (Other)
0.000 0.329 0.671
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.329 0.671
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.329 0.671
M06.33 Rheumatoid nodule (Forearm)
0.000 0.329 0.671
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.329 0.671
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.335 0.665
D55-D59 Haemolytic anaemias
0.000 0.335 0.665
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.335 0.664
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.000 0.335 0.664
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.336 0.664
E11.8 With unspecified complications
0.000 0.337 0.663
L42 Pityriasis rosea
0.000 0.340 0.660
I13 Hypertensive heart and renal disease
0.000 0.342 0.657
I24.8 Other forms of acute ischaemic heart disease
0.000 0.343 0.657
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.657 0.343 0.001
E78.1 Pure hyperglyceridaemia
0.000 0.344 0.656
I22.8 Subsequent myocardial infarction of other sites
0.000 0.347 0.653
E89.3 Postprocedural hypopituitarism
0.000 0.347 0.653
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.348 0.652
M24 Other specific joint derangements
0.000 0.349 0.651
E84 Cystic fibrosis
0.000 0.349 0.651
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.349 0.650
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.350 0.650
I83 Varicose veins of lower extremities
0.649 0.351 0.000
K70-K77 Diseases of liver
0.000 0.360 0.640
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.360 0.639
K90-K93 Other diseases of the digestive system
0.000 0.361 0.639
Chapter XI Diseases of the digestive system
0.000 0.364 0.636
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.365 0.635
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.366 0.634
K75 Other inflammatory liver diseases
0.000 0.366 0.634
K75.4 Autoimmune hepatitis
0.000 0.367 0.633
H35.2 Other proliferative retinopathy
0.000 0.368 0.632
E89.0 Postprocedural hypothyroidism
0.000 0.369 0.631
I25.4 Coronary artery aneurysm
0.000 0.370 0.630
E07 Other disorders of thyroid
0.000 0.370 0.630
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.371 0.629
K74 Fibrosis and cirrhosis of liver
0.000 0.375 0.625
I15.8 Other secondary hypertension
0.000 0.375 0.624
I15.2 Hypertension secondary to endocrine disorders
0.000 0.375 0.624
I15.0 Renovascular hypertension
0.000 0.375 0.624
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.377 0.623
D51 Vitamin B12 deficiency anaemia
0.000 0.379 0.621
E03.8 Other specified hypothyroidism
0.000 0.380 0.620
G70-G73 Diseases of myoneural junction and muscle
0.008 0.380 0.612
E89.4 Postprocedural ovarian failure
0.000 0.381 0.619
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.383 0.617
E89.2 Postprocedural hypoparathyroidism
0.000 0.384 0.616
I25.2 Old myocardial infarction
0.000 0.386 0.614
H30.8 Other chorioretinal inflammations
0.000 0.386 0.614
H30.2 Posterior cyclitis
0.000 0.386 0.614
H30.1 Disseminated chorioretinal inflammation
0.000 0.386 0.614
H30.0 Focal chorioretinal inflammation
0.000 0.386 0.614
K74.3 Primary biliary cirrhosis
0.000 0.386 0.614
M65.8 Other synovitis and tenosynovitis
0.000 0.387 0.613
E16.1 Other hypoglycaemia
0.000 0.387 0.613
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.391 0.609
M00-M03 Infectious arthropathies
0.000 0.391 0.608
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.000 0.392 0.608
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.392 0.607
G50-G59 Nerve, nerve root and plexus disorders
0.004 0.393 0.603
I24.1 Dressler's syndrome
0.000 0.394 0.606
E88 Other metabolic disorders
0.000 0.394 0.606
E50-E64 Other nutritional deficiencies
0.000 0.397 0.603
M34.8 Other forms of systemic sclerosis
0.000 0.397 0.603
E73 Lactose intolerance
0.000 0.398 0.602
M34.0 Progressive systemic sclerosis
0.000 0.398 0.602
G90-G99 Other disorders of the nervous system
0.004 0.398 0.598
M35.8 Other specified systemic involvement of connective tissue
0.000 0.398 0.602
I07 Rheumatic tricuspid valve diseases
0.000 0.399 0.601
M32 Systemic lupus erythematosus
0.000 0.399 0.601
G59 Mononeuropathy in diseases classified elsewhere
0.002 0.399 0.599
H20.2 Lens-induced iridocyclitis
0.000 0.401 0.599
H20.1 Chronic iridocyclitis
0.000 0.402 0.598
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.402 0.598
G59.0 Diabetic mononeuropathy
0.000 0.402 0.598
D50 Iron deficiency anaemia
0.000 0.404 0.596
E83 Disorders of mineral metabolism
0.498 0.404 0.097
I08.0 Disorders of both mitral and aortic valves
0.000 0.405 0.595
H40-H42 Glaucoma
0.000 0.405 0.595
M35.0 Sicca syndrome [Sjogren]
0.000 0.406 0.594
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.406 0.594
M70-M79 Other soft tissue disorders
0.000 0.409 0.591
I83.0 Varicose veins of lower extremities with ulcer
0.591 0.409 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.410 0.590
I09.9 Rheumatic heart disease, unspecified
0.000 0.410 0.590
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.410 0.589
G56 Mononeuropathies of upper limb
0.000 0.410 0.589
G56.0 Carpal tunnel syndrome
0.000 0.411 0.589
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.412 0.588
M80-M85 Disorders of bone density and structure
0.000 0.412 0.588
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.413 0.587
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.413 0.587
E89.5 Postprocedural testicular hypofunction
0.000 0.413 0.587
E89.1 Postprocedural hypoinsulinaemia
0.000 0.413 0.587
E46 Unspecified protein-energy malnutrition
0.000 0.414 0.586
M13 Other arthritis
0.000 0.419 0.581
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.004 0.419 0.577
H35.6 Retinal haemorrhage
0.000 0.420 0.580
H15.1 Episcleritis
0.000 0.420 0.580
H15.8 Other disorders of sclera
0.000 0.421 0.579
K74.5 Biliary cirrhosis, unspecified
0.000 0.422 0.578
G91 Hydrocephalus
0.001 0.422 0.577
L40.3 Pustulosis palmaris et plantaris
0.000 0.422 0.578
M34.9 Systemic sclerosis, unspecified
0.000 0.423 0.577
D50.9 Iron deficiency anaemia, unspecified
0.000 0.423 0.577
H35.1 Retinopathy of prematurity
0.000 0.425 0.575
M60-M63 Disorders of muscles
0.000 0.426 0.574
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.426 0.574
D61.1 Drug-induced aplastic anaemia
0.000 0.427 0.573
M12.3 Palindromic rheumatism
0.000 0.427 0.573
M65.84 Other synovitis and tenosynovitis (Hand)
0.000 0.427 0.573
G91.9 Hydrocephalus, unspecified
0.000 0.429 0.571
H21.0 Hyphaema
0.000 0.429 0.571
M24.0 Loose body in joint
0.000 0.432 0.568
K72 Hepatic failure, not elsewhere classified
0.000 0.433 0.567
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.434 0.566
M14.4 Arthropathy in amyloidosis
0.000 0.434 0.566
M14.3 Lipoid dermatoarthritis
0.000 0.434 0.566
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.434 0.566
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.434 0.566
L50-L54 Urticaria and erythema
0.000 0.434 0.566
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.434 0.565
M25 Other joint disorders, not elsewhere classified
0.000 0.437 0.563
M30.0 Polyarteritis nodosa
0.000 0.441 0.559
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.442 0.558
H35.7 Separation of retinal layers
0.000 0.442 0.558
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.000 0.442 0.558
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.443 0.557
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.443 0.557
M24.6 Ankylosis of joint
0.000 0.443 0.557
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.445 0.555
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.446 0.554
M25.4 Effusion of joint
0.000 0.448 0.552
M91-M94 Chondropathies
0.000 0.449 0.551
H17 Corneal scars and opacities
0.000 0.449 0.550
H33.0 Retinal detachment with retinal break
0.000 0.450 0.550
M11 Other crystal arthropathies
0.000 0.450 0.549
K73 Chronic hepatitis, not elsewhere classified
0.000 0.450 0.549
M77 Other enthesopathies
0.000 0.451 0.549
H33.4 Traction detachment of retina
0.000 0.453 0.547
D64.8 Other specified anaemias
0.000 0.453 0.546
M24.7 Protrusio acetabuli
0.000 0.455 0.545
G72 Other myopathies
0.002 0.455 0.543
M25.46 Effusion of joint (Lower leg)
0.000 0.455 0.545
M82 Osteoporosis in diseases classified elsewhere
0.000 0.455 0.545
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.456 0.544
E45 Retarded development following protein-energy malnutrition
0.000 0.456 0.544
E43 Unspecified severe protein-energy malnutrition
0.000 0.456 0.544
E42 Marasmic kwashiorkor
0.000 0.456 0.544
E41 Nutritional marasmus
0.000 0.456 0.544
E40 Kwashiorkor
0.000 0.456 0.544
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.457 0.543
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.458 0.541
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.458 0.541
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.458 0.541
E74.2 Disorders of galactose metabolism
0.000 0.458 0.541
E74.1 Disorders of fructose metabolism
0.000 0.458 0.541
E74.0 Glycogen storage disease
0.000 0.458 0.541
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.460 0.540
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.461 0.539
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.464 0.536
M70.4 Prepatellar bursitis
0.000 0.465 0.535
M80 Osteoporosis with pathological fracture
0.000 0.466 0.534
M33.1 Other dermatomyositis
0.000 0.468 0.532
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.468 0.531
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.470 0.530
M49.4 Neuropathic spondylopathy
0.000 0.470 0.530
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.470 0.530
M49.2 Enterobacterial spondylitis
0.000 0.470 0.530
M49.1 Brucella spondylitis
0.000 0.470 0.530
M49.0 Tuberculosis of spine
0.000 0.470 0.530
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.471 0.529
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.471 0.529
M30.2 Juvenile polyarteritis
0.000 0.471 0.529
H21.2 Degeneration of iris and ciliary body
0.000 0.473 0.527
E80.6 Other disorders of bilirubin metabolism
0.000 0.473 0.527
E13.9 Without complications
0.000 0.473 0.527
H35.5 Hereditary retinal dystrophy
0.000 0.475 0.525
E80.2 Other porphyria
0.000 0.475 0.524
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.476 0.524
M12.5 Traumatic arthropathy
0.000 0.476 0.524
M12.4 Intermittent hydrarthrosis
0.000 0.476 0.524

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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