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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2857161
log Bayes Factor = 85.2086
Chromosome 6   position 32,759,297  (GRCh37) Explore rs2857161 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
M07 Psoriatic and enteropathic arthropathies
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
M07.3 Other psoriatic arthropathies
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
L57.0 Actinic keratosis
0.000 0.003 0.997
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.003 0.997
H36.0 Diabetic retinopathy
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.994 0.006 0.000
G37 Other demyelinating diseases of central nervous system
0.993 0.007 0.000
D04 Carcinoma in situ of skin
0.000 0.007 0.993
D00-D09 In situ neoplasms
0.000 0.008 0.992
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.009 0.991
G37.9 Demyelinating disease of central nervous system, unspecified
0.990 0.010 0.000
E10.4 With neurological complications
0.000 0.025 0.975
D04.7 Skin of lower limb, including hip
0.000 0.027 0.973
E10.1 With ketoacidosis
0.000 0.029 0.971
E70-E90 Metabolic disorders
0.000 0.030 0.970
E10.5 With peripheral circulatory complications
0.000 0.033 0.967
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.035 0.965
D04.5 Skin of trunk
0.000 0.036 0.964
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.038 0.962
D06 Carcinoma in situ of cervix uteri
0.000 0.040 0.960
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.044 0.956
E89.0 Postprocedural hypothyroidism
0.000 0.058 0.942
C44 Other malignant neoplasms of skin
0.000 0.061 0.939
C44.7 Skin of lower limb, including hip
0.000 0.062 0.938
D06.9 Cervix, unspecified
0.000 0.064 0.936
E78.0 Pure hypercholesterolaemia
0.000 0.065 0.935
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.066 0.934
C44.6 Skin of upper limb, including shoulder
0.000 0.067 0.933
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.067 0.933
D04.3 Skin of other and unspecified parts of face
0.000 0.068 0.932
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.071 0.929
L40.5 Arthropathic psoriasis
0.000 0.072 0.928
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.076 0.924
Chapter II Neoplasms
0.000 0.077 0.923
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.079 0.921
M06.3 Rheumatoid nodule
0.000 0.080 0.920
M06.0 Seronegative rheumatoid arthritis
0.000 0.080 0.920
E10.2 With renal complications
0.000 0.087 0.913
D09 Carcinoma in situ of other and unspecified sites
0.000 0.088 0.912
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.088 0.912
L40 Psoriasis
0.000 0.092 0.908
D03 Melanoma in situ
0.000 0.093 0.907
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.094 0.906
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.097 0.903
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.098 0.902
E10.0 With coma
0.000 0.101 0.899
C83.3 Large cell (diffuse)
0.000 0.110 0.890
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.112 0.888
L40-L45 Papulosquamous disorders
0.000 0.116 0.884
G37.8 Other specified demyelinating diseases of central nervous system
0.882 0.118 0.000
E11.5 With peripheral circulatory complications
0.000 0.119 0.881
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.124 0.876
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.130 0.870
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.132 0.868
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.135 0.865
D04.4 Skin of scalp and neck
0.000 0.141 0.859
E16 Other disorders of pancreatic internal secretion
0.000 0.151 0.849
E10.8 With unspecified complications
0.000 0.153 0.847
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.155 0.845
E78.6 Lipoprotein deficiency
0.000 0.157 0.843
E06 Thyroiditis
0.000 0.159 0.841
D03.5 Melanoma in situ of trunk
0.000 0.160 0.840
D09.0 Bladder
0.000 0.167 0.833
C44.3 Skin of other and unspecified parts of face
0.000 0.169 0.831
E83.1 Disorders of iron metabolism
0.827 0.173 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.173 0.827
L40.9 Psoriasis, unspecified
0.000 0.175 0.825
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.179 0.821
E11.1 With ketoacidosis
0.000 0.184 0.816
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.815 0.185 0.000
E10.6 With other specified complications
0.000 0.185 0.815
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.191 0.809
C43 Malignant melanoma of skin
0.000 0.194 0.806
C91 Lymphoid leukaemia
0.000 0.195 0.805
D04.9 Skin, unspecified
0.000 0.195 0.805
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.195 0.805
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.199 0.801
M10 Gout
0.000 0.200 0.800
E11.0 With coma
0.000 0.200 0.800
E89.4 Postprocedural ovarian failure
0.000 0.204 0.796
E06.3 Autoimmune thyroiditis
0.000 0.207 0.793
E20-E35 Disorders of other endocrine glands
0.000 0.211 0.789
H36 Retinal disorders in diseases classified elsewhere
0.000 0.214 0.786
C85.1 B-cell lymphoma, unspecified
0.000 0.216 0.784
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.217 0.783
M06.34 Rheumatoid nodule (Hand)
0.000 0.220 0.780
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.222 0.778
E89.3 Postprocedural hypopituitarism
0.000 0.223 0.777
C82.0 Small cleaved cell, follicular
0.000 0.223 0.777
C44.4 Skin of scalp and neck
0.000 0.228 0.772
C82.2 Large cell, follicular
0.000 0.231 0.769
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.232 0.768
E78.1 Pure hyperglyceridaemia
0.000 0.232 0.768
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.233 0.767
M06.4 Inflammatory polyarthropathy
0.000 0.234 0.766
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.240 0.760
E88 Other metabolic disorders
0.000 0.241 0.759
E78.2 Mixed hyperlipidaemia
0.000 0.245 0.755
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.246 0.754
L43 Lichen planus
0.000 0.247 0.753
E79 Disorders of purine and pyrimidine metabolism
0.000 0.247 0.753
E89.2 Postprocedural hypoparathyroidism
0.000 0.251 0.749
E14 Unspecified diabetes mellitus
0.000 0.251 0.749
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.252 0.748
E05.8 Other thyrotoxicosis
0.000 0.253 0.747
G36 Other acute disseminated demyelination
0.746 0.254 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.254 0.746
C83.1 Small cleaved cell (diffuse)
0.000 0.256 0.744
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.257 0.743
E27 Other disorders of adrenal gland
0.000 0.259 0.741
E13 Other specified diabetes mellitus
0.000 0.259 0.741
D04.2 Skin of ear and external auricular canal
0.000 0.265 0.735
L40.1 Generalised pustular psoriasis
0.000 0.270 0.730
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.271 0.729
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.271 0.729
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.274 0.726
C44.0 Skin of lip
0.000 0.276 0.724
D09.1 Other and unspecified urinary organs
0.000 0.277 0.723
E27.1 Primary adrenocortical insufficiency
0.000 0.278 0.722
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.278 0.722
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.280 0.720
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
M07.6 Other enteropathic arthropathies
0.000 0.283 0.717
M07.5 Arthropathy in ulcerative colitis
0.000 0.283 0.717
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.283 0.717
M07.2 Psoriatic spondylitis
0.000 0.283 0.717
M07.1 Arthritis mutilans
0.000 0.283 0.717
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.283 0.717
M07.38 Other psoriatic arthropathies (Other)
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.283 0.717
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.283 0.717
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.283 0.717
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.284 0.716
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.284 0.716
C91.9 Lymphoid leukaemia, unspecified
0.000 0.284 0.716
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.712 0.288 0.000
G37.4 Subacute necrotising myelitis
0.712 0.288 0.000
G37.2 Central pontine myelinolysis
0.712 0.288 0.000
G37.1 Central demyelination of corpus callosum
0.712 0.288 0.000
G37.0 Diffuse sclerosis
0.712 0.288 0.000
D04.8 Skin of other sites
0.000 0.288 0.712
D04.0 Skin of lip
0.000 0.288 0.712
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.289 0.711
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.290 0.710
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.290 0.710
E78.5 Hyperlipidaemia, unspecified
0.000 0.290 0.710
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.291 0.709
E84 Cystic fibrosis
0.000 0.291 0.709
D06.0 Endocervix
0.000 0.298 0.702
E23 Hypofunction and other disorders of pituitary gland
0.000 0.299 0.701
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.300 0.700
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.300 0.700
E03.1 Congenital hypothyroidism without goitre
0.000 0.301 0.699
M06.8 Other specified rheumatoid arthritis
0.000 0.303 0.697
M11 Other crystal arthropathies
0.000 0.304 0.696
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.304 0.696
E77 Disorders of glycoprotein metabolism
0.000 0.305 0.695
E76 Disorders of glycosaminoglycan metabolism
0.000 0.305 0.695
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.305 0.695
E70 Disorders of aromatic amino-acid metabolism
0.000 0.305 0.695
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.305 0.695
E16.1 Other hypoglycaemia
0.000 0.309 0.691
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.310 0.690
E89.5 Postprocedural testicular hypofunction
0.000 0.310 0.690
D06.7 Other parts of cervix
0.000 0.312 0.688
D06.1 Exocervix
0.000 0.312 0.688
D03.3 Melanoma in situ of other and unspecified parts of face
0.000 0.314 0.686
L42 Pityriasis rosea
0.000 0.314 0.686
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.315 0.684
E16.2 Hypoglycaemia, unspecified
0.000 0.316 0.684
E03.8 Other specified hypothyroidism
0.000 0.316 0.684
D04.6 Skin of upper limb, including shoulder
0.000 0.317 0.683
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.318 0.682
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.319 0.681
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.322 0.677
C83.7 Burkitt's tumour
0.000 0.325 0.674
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.327 0.673
C44.8 Overlapping lesion of skin
0.000 0.327 0.673
E89.1 Postprocedural hypoinsulinaemia
0.000 0.330 0.670
E11.2 With renal complications
0.000 0.331 0.669
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.334 0.666
E14.3 With ophthalmic complications
0.000 0.334 0.666
M14 Arthropathies in other diseases classified elsewhere
0.000 0.337 0.663
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.337 0.662
C85.0 Lymphosarcoma
0.000 0.337 0.662
D03.4 Melanoma in situ of scalp and neck
0.000 0.338 0.662
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.340 0.660
M06.38 Rheumatoid nodule (Other)
0.000 0.340 0.660
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.340 0.660
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.340 0.660
M06.33 Rheumatoid nodule (Forearm)
0.000 0.340 0.660
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.340 0.660
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.340 0.659
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.340 0.659
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.340 0.659
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.340 0.659
M12 Other specific arthropathies
0.000 0.343 0.656
E11.6 With other specified complications
0.000 0.344 0.656
D09.9 Carcinoma in situ, unspecified
0.000 0.346 0.654
D09.7 Carcinoma in situ of other specified sites
0.000 0.346 0.654
D09.3 Thyroid and other endocrine glands
0.000 0.346 0.654
D09.2 Eye
0.000 0.346 0.654
E15 Nondiabetic hypoglycaemic coma
0.000 0.346 0.654
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.346 0.653
L40.3 Pustulosis palmaris et plantaris
0.000 0.349 0.651
L40.2 Acrodermatitis continua
0.000 0.349 0.651
M05.2 Rheumatoid vasculitis
0.000 0.350 0.650
D03.9 Melanoma in situ, unspecified
0.000 0.350 0.650
D03.8 Melanoma in situ of other sites
0.000 0.350 0.650
C86 Other specified types of T/NK-cell lymphoma
0.000 0.350 0.650
L57.5 Actinic granuloma
0.000 0.350 0.649
L57.3 Poikiloderma of Civatte
0.000 0.350 0.649
L57.2 Cutis rhomboidalis nuchae
0.000 0.350 0.649
L57.1 Actinic reticuloid
0.000 0.350 0.649
C91.5 Adult T-cell leukaemia
0.000 0.351 0.649
L43.8 Other lichen planus
0.000 0.352 0.648
C82.6 Cutaneous follicle centre lymphoma
0.000 0.353 0.647
C82.5 Diffuse follicle centre lymphoma
0.000 0.353 0.647
C82.4 Follicular lymphoma grade IIIb
0.000 0.353 0.647
L40.4 Guttate psoriasis
0.000 0.353 0.647
C83.6 Undifferentiated (diffuse)
0.000 0.353 0.647
C83.5 Lymphoblastic (diffuse)
0.000 0.353 0.647
C83.4 Immunoblastic (diffuse)
0.000 0.353 0.647
C83.2 Mixed small and large cell (diffuse)
0.000 0.353 0.647
M10.0 Idiopathic gout
0.000 0.357 0.643
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.357 0.643
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.358 0.642
C88 Malignant immunoproliferative diseases
0.000 0.358 0.642
D00.1 Oesophagus
0.000 0.360 0.640
E88.8 Other specified metabolic disorders
0.000 0.362 0.638
# Top node
0.000 0.362 0.638
E07 Other disorders of thyroid
0.000 0.364 0.636
D04.1 Skin of eyelid, including canthus
0.000 0.365 0.635
H30-H36 Disorders of choroid and retina
0.000 0.365 0.635
C91.0 Acute lymphoblastic leukaemia
0.000 0.365 0.635
L44 Other papulosquamous disorders
0.000 0.366 0.634
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.366 0.634
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.367 0.633
E11.8 With unspecified complications
0.000 0.368 0.632
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.370 0.630
C73 Malignant neoplasm of thyroid gland
0.000 0.371 0.629
D03.0 Melanoma in situ of lip
0.000 0.372 0.628
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.374 0.626
C94 Other leukaemias of specified cell type
0.000 0.375 0.625
E73 Lactose intolerance
0.000 0.375 0.624
D07.2 Vagina
0.000 0.375 0.624
E85 Amyloidosis
0.000 0.376 0.623
L55 Sunburn
0.000 0.378 0.622
E23.7 Disorder of pituitary gland, unspecified
0.000 0.378 0.622
C43.4 Malignant melanoma of scalp and neck
0.000 0.378 0.622
H35 Other retinal disorders
0.000 0.381 0.619
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.383 0.617
L41 Parapsoriasis
0.000 0.383 0.617
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.384 0.616
M13 Other arthritis
0.000 0.384 0.616
E06.5 Other chronic thyroiditis
0.000 0.385 0.615
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.386 0.614
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.387 0.613
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.388 0.612
E14.4 With neurological complications
0.000 0.390 0.610
C82.3 Follicular lymphoma grade IIIa
0.000 0.390 0.610
D00.0 Lip, oral cavity and pharynx
0.000 0.391 0.609
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.391 0.608
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.391 0.608
E16.4 Abnormal secretion of gastrin
0.000 0.391 0.608
E16.3 Increased secretion of glucagon
0.000 0.391 0.608
E65-E68 Obesity and other hyperalimentation
0.000 0.392 0.608
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.392 0.608
E88.9 Metabolic disorder, unspecified
0.000 0.392 0.608
D02.0 Larynx
0.000 0.392 0.607
C93 Monocytic leukaemia
0.000 0.394 0.606
E06.4 Drug-induced thyroiditis
0.000 0.397 0.603
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.397 0.603
E06.0 Acute thyroiditis
0.000 0.397 0.603
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.397 0.603
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.402 0.598
L57.4 Cutis laxa senilis
0.000 0.403 0.597
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.403 0.597
M10.9 Gout, unspecified
0.000 0.405 0.595
E23.6 Other disorders of pituitary gland
0.000 0.405 0.595
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.406 0.594
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.407 0.592
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.408 0.592
E78.3 Hyperchylomicronaemia
0.000 0.408 0.591
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.411 0.589
L58 Radiodermatitis
0.000 0.414 0.586
E14.1 With ketoacidosis
0.000 0.415 0.585
D07.4 Penis
0.000 0.415 0.585
L40.0 Psoriasis vulgaris
0.000 0.415 0.585
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.416 0.584
H35.6 Retinal haemorrhage
0.000 0.418 0.582
E28 Ovarian dysfunction
0.000 0.421 0.579
C95 Leukaemia of unspecified cell type
0.000 0.422 0.578
C43.8 Overlapping malignant melanoma of skin
0.000 0.422 0.578
C43.0 Malignant melanoma of lip
0.000 0.422 0.578
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.422 0.577
C91.7 Other lymphoid leukaemia
0.000 0.422 0.577
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.422 0.577
C91.3 Prolymphocytic leukaemia
0.000 0.422 0.577
C91.2 Subacute lymphocytic leukaemia
0.000 0.422 0.577
H35.8 Other specified retinal disorders
0.000 0.424 0.576
D00.2 Stomach
0.000 0.425 0.574
M10.4 Other secondary gout
0.000 0.426 0.574
M10.2 Drug-induced gout
0.000 0.426 0.574
M10.1 Lead-induced gout
0.000 0.426 0.574
M10.3 Gout due to impairment of renal function
0.000 0.428 0.572
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.429 0.571
E83 Disorders of mineral metabolism
0.039 0.429 0.532
E72 Other disorders of amino-acid metabolism
0.000 0.432 0.568
G36.0 Neuromyelitis optica [Devic]
0.568 0.432 0.000
E40-E46 Malnutrition
0.000 0.434 0.566
L82 Seborrhoeic keratosis
0.000 0.434 0.566
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.434 0.566
E32 Diseases of thymus
0.000 0.434 0.566
E31 Polyglandular dysfunction
0.000 0.434 0.566
E30 Disorders of puberty, not elsewhere classified
0.000 0.434 0.566
M11.9 Crystal arthropathy, unspecified
0.000 0.435 0.565
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.436 0.563
L43.9 Lichen planus, unspecified
0.000 0.438 0.562
E14.5 With peripheral circulatory complications
0.000 0.441 0.559
E78.8 Other disorders of lipoprotein metabolism
0.000 0.442 0.557
C91.4 Hairy-cell leukaemia
0.000 0.443 0.557
H35.2 Other proliferative retinopathy
0.000 0.443 0.557
D01.0 Colon
0.000 0.444 0.556
E13.9 Without complications
0.000 0.445 0.555
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.445 0.554
E88.3 Tumour lysis syndrome
0.000 0.446 0.554
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.447 0.553
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.447 0.553
M13.1 Monoarthritis, not elsewhere classified
0.000 0.448 0.552
D02.4 Respiratory system, unspecified
0.000 0.449 0.551
D02.3 Other parts of respiratory system
0.000 0.449 0.551
D02.2 Bronchus and lung
0.000 0.449 0.551
D02.1 Trachea
0.000 0.449 0.551
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.451 0.549
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.451 0.549
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.451 0.549
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.451 0.549
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.451 0.549
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.451 0.549
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.451 0.549
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.451 0.549
E20 Hypoparathyroidism
0.000 0.458 0.542
L43.3 Subacute (active) lichen planus
0.000 0.460 0.540
L43.2 Lichenoid drug reaction
0.000 0.460 0.540
L43.1 Bullous lichen planus
0.000 0.460 0.540
L43.0 Hypertrophic lichen planus
0.000 0.460 0.540
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.460 0.540
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.460 0.540
E79.1 Lesch-Nyhan syndrome
0.000 0.460 0.540
E24 Cushing's syndrome
0.000 0.462 0.538
C12 Malignant neoplasm of pyriform sinus
0.000 0.462 0.538
E14.7 With multiple complications
0.000 0.463 0.537
E14.0 With coma
0.000 0.463 0.537
G36.9 Acute disseminated demyelination, unspecified
0.535 0.465 0.000
G36.8 Other specified acute disseminated demyelination
0.535 0.465 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.535 0.465 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.467 0.533
D01.3 Anus and anal canal
0.000 0.468 0.532
E27.5 Adrenomedullary hyperfunction
0.000 0.468 0.531
E27.0 Other adrenocortical overactivity
0.000 0.468 0.531
E80.1 Porphyria cutanea tarda
0.000 0.469 0.531
E13.8 With unspecified complications
0.000 0.469 0.531
E13.7 With multiple complications
0.000 0.469 0.531
E13.6 With other specified complications
0.000 0.469 0.531
E13.5 With peripheral circulatory complications
0.000 0.469 0.531
E13.4 With neurological complications
0.000 0.469 0.531
E13.3 With ophthalmic complications
0.000 0.469 0.531
E13.2 With renal complications
0.000 0.469 0.531
E13.1 With ketoacidosis
0.000 0.469 0.531
E13.0 With coma
0.000 0.469 0.531
D07.1 Vulva
0.000 0.469 0.531
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.470 0.530
H30 Chorioretinal inflammation
0.000 0.470 0.530
L85 Other epidermal thickening
0.000 0.470 0.530
E88.2 Lipomatosis, not elsewhere classified
0.000 0.470 0.530
L94 Other localised connective tissue disorders
0.000 0.471 0.529
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.473 0.527
Chapter VII Diseases of the eye and adnexa
0.000 0.475 0.525
E23.2 Diabetes insipidus
0.000 0.475 0.525
C81 Hodgkin's disease
0.000 0.477 0.523
E84.9 Cystic fibrosis, unspecified
0.000 0.478 0.521
M10.09 Idiopathic gout (Site unspecified)
0.000 0.479 0.521
E14.8 With unspecified complications
0.000 0.479 0.521
E29 Testicular dysfunction
0.000 0.481 0.519
M13.8 Other specified arthritis
0.000 0.482 0.518
L10-L14 Bullous disorders
0.000 0.484 0.516
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.484 0.516
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M08.9 Juvenile arthritis, unspecified
0.000 0.486 0.514
M08.8 Other juvenile arthritis
0.000 0.486 0.514
M08.4 Pauciarticular juvenile arthritis
0.000 0.486 0.514
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.486 0.514
M08.2 Juvenile arthritis with systemic onset
0.000 0.486 0.514
M08.1 Juvenile ankylosing spondylitis
0.000 0.486 0.514
M08.0 Juvenile rheumatoid arthritis
0.000 0.486 0.514
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.486 0.514
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.486 0.514
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.486 0.514
M09.0 Juvenile arthritis in psoriasis
0.000 0.486 0.514
M05.09 Felty's syndrome (Site unspecified)
0.000 0.486 0.514
M05.08 Felty's syndrome (Other)
0.000 0.486 0.514
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.486 0.514
M05.06 Felty's syndrome (Lower leg)
0.000 0.486 0.514
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.486 0.514
M05.04 Felty's syndrome (Hand)
0.000 0.486 0.514
M05.03 Felty's syndrome (Forearm)
0.000 0.486 0.514
M05.02 Felty's syndrome (Upper arm)
0.000 0.486 0.514
M05.01 Felty's syndrome (Shoulder region)
0.000 0.486 0.514
M05.00 Felty's syndrome (Multiple sites)
0.000 0.486 0.514
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.486 0.514
M05.18 Rheumatoid lung disease (Other)
0.000 0.486 0.514
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.486 0.514
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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