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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9379844
log Bayes Factor = 48.0451
Chromosome 6   position 26,291,527  (GRCh37) Explore rs9379844 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.021 0.979
E10-E14 Diabetes mellitus
0.000 0.022 0.978
E10 Insulin-dependent diabetes mellitus
0.000 0.027 0.973
E11.2 With renal complications
0.000 0.053 0.947
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.060 0.940
E83 Disorders of mineral metabolism
0.000 0.064 0.936
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.070 0.930
I10 Essential (primary) hypertension
0.000 0.073 0.927
E70-E90 Metabolic disorders
0.000 0.076 0.924
E16 Other disorders of pancreatic internal secretion
0.000 0.077 0.923
E16.2 Hypoglycaemia, unspecified
0.000 0.082 0.918
E10.0 With coma
0.000 0.096 0.904
E11.5 With peripheral circulatory complications
0.000 0.096 0.904
E10.5 With peripheral circulatory complications
0.000 0.109 0.891
E11.4 With neurological complications
0.000 0.119 0.881
E10.3 With ophthalmic complications
0.000 0.125 0.875
E11.3 With ophthalmic complications
0.000 0.132 0.868
E11.9 Without complications
0.000 0.139 0.861
E40-E46 Malnutrition
0.000 0.148 0.852
E10.1 With ketoacidosis
0.000 0.162 0.838
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.199 0.801
E46 Unspecified protein-energy malnutrition
0.000 0.211 0.789
E88 Other metabolic disorders
0.000 0.213 0.787
E11.6 With other specified complications
0.000 0.220 0.780
E10.8 With unspecified complications
0.000 0.238 0.762
E73 Lactose intolerance
0.000 0.262 0.738
E11.1 With ketoacidosis
0.000 0.263 0.737
E10.2 With renal complications
0.000 0.271 0.729
E84 Cystic fibrosis
0.000 0.280 0.720
E80.4 Gilbert's syndrome
0.000 0.292 0.708
E11.7 With multiple complications
0.000 0.298 0.702
E11.0 With coma
0.000 0.299 0.701
E12 Malnutrition-related diabetes mellitus
0.000 0.299 0.701
E10.7 With multiple complications
0.000 0.302 0.698
E14 Unspecified diabetes mellitus
0.000 0.316 0.684
E10.4 With neurological complications
0.000 0.317 0.683
E79 Disorders of purine and pyrimidine metabolism
0.000 0.317 0.682
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.328 0.672
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.329 0.671
E83.8 Other disorders of mineral metabolism
0.000 0.329 0.671
E83.2 Disorders of zinc metabolism
0.000 0.329 0.671
E83.0 Disorders of copper metabolism
0.000 0.329 0.671
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.333 0.667
E15 Nondiabetic hypoglycaemic coma
0.000 0.333 0.667
E10.9 Without complications
0.000 0.337 0.663
E76 Disorders of glycosaminoglycan metabolism
0.000 0.338 0.662
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.338 0.662
E70 Disorders of aromatic amino-acid metabolism
0.000 0.338 0.662
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.338 0.662
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.338 0.662
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.338 0.662
E16.4 Abnormal secretion of gastrin
0.000 0.338 0.662
E16.3 Increased secretion of glucagon
0.000 0.338 0.662
E88.8 Other specified metabolic disorders
0.000 0.354 0.646
E83.3 Disorders of phosphorus metabolism
0.000 0.354 0.646
E16.1 Other hypoglycaemia
0.000 0.356 0.643
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.361 0.639
E77 Disorders of glycoprotein metabolism
0.000 0.371 0.629
E80.2 Other porphyria
0.000 0.375 0.625
E10.6 With other specified complications
0.000 0.380 0.620
E13 Other specified diabetes mellitus
0.000 0.384 0.616
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.389 0.611
E45 Retarded development following protein-energy malnutrition
0.000 0.389 0.611
E43 Unspecified severe protein-energy malnutrition
0.000 0.389 0.611
E42 Marasmic kwashiorkor
0.000 0.389 0.611
E41 Nutritional marasmus
0.000 0.389 0.611
E40 Kwashiorkor
0.000 0.389 0.611
E73.9 Lactose intolerance, unspecified
0.000 0.395 0.605
E14.3 With ophthalmic complications
0.000 0.398 0.602
E72 Other disorders of amino-acid metabolism
0.000 0.406 0.593
E74 Other disorders of carbohydrate metabolism
0.000 0.412 0.587
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.421 0.579
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.425 0.575
E80.5 Crigler-Najjar syndrome
0.000 0.425 0.575
E80.3 Defects of catalase and peroxydase
0.000 0.425 0.575
E80.1 Porphyria cutanea tarda
0.000 0.425 0.575
E80.0 Hereditary erythropoietic porphyria
0.000 0.425 0.575
E84.9 Cystic fibrosis, unspecified
0.000 0.426 0.574
E88.3 Tumour lysis syndrome
0.000 0.436 0.564
E14.6 With other specified complications
0.000 0.438 0.562
E88.9 Metabolic disorder, unspecified
0.000 0.444 0.556
E88.2 Lipomatosis, not elsewhere classified
0.000 0.454 0.546
E80.6 Other disorders of bilirubin metabolism
0.000 0.471 0.529
E73.8 Other lactose intolerance
0.000 0.471 0.529
E73.1 Secondary lactase deficiency
0.000 0.471 0.529
E73.0 Congenital lactase deficiency
0.000 0.471 0.529
E14.5 With peripheral circulatory complications
0.000 0.483 0.517
E84.8 Cystic fibrosis with other manifestations
0.000 0.484 0.516
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.484 0.516
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.484 0.516
E65-E68 Obesity and other hyperalimentation
0.000 0.487 0.513
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.490 0.510
E12.9 Without complications
0.000 0.497 0.503
E12.8 With unspecified complications
0.000 0.497 0.503
E12.7 With multiple complications
0.000 0.497 0.503
E12.6 With other specified complications
0.000 0.497 0.503
E12.5 With peripheral circulatory complications
0.000 0.497 0.503
E12.4 With neurological complications
0.000 0.497 0.503
E12.3 With ophthalmic complications
0.000 0.497 0.503
E12.2 With renal complications
0.000 0.497 0.503
E12.1 With ketoacidosis
0.000 0.497 0.503
E12.0 With coma
0.000 0.497 0.503
E14.1 With ketoacidosis
0.000 0.501 0.499
E83.4 Disorders of magnesium metabolism
0.000 0.503 0.497
E14.8 With unspecified complications
0.000 0.507 0.493
E14.7 With multiple complications
0.000 0.509 0.490
E14.0 With coma
0.000 0.509 0.490
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.510 0.489
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.510 0.489
E79.1 Lesch-Nyhan syndrome
0.000 0.510 0.489
E11.8 With unspecified complications
0.000 0.515 0.485
E75.5 Other lipid storage disorders
0.000 0.517 0.483
E75.6 Lipid storage disorder, unspecified
0.000 0.521 0.478
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.521 0.478
E75.3 Sphingolipidosis, unspecified
0.000 0.521 0.478
E75.2 Other sphingolipidosis
0.000 0.521 0.478
E75.1 Other gangliosidosis
0.000 0.521 0.478
E75.0 GM2 gangliosidosis
0.000 0.521 0.478
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.525 0.475
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.525 0.475
E70.3 Albinism
0.000 0.525 0.475
E70.2 Disorders of tyrosine metabolism
0.000 0.525 0.475
E70.1 Other hyperphenylalaninaemias
0.000 0.525 0.475
E70.0 Classical phenylketonuria
0.000 0.525 0.475
E71.3 Disorders of fatty-acid metabolism
0.000 0.525 0.475
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.525 0.475
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.525 0.475
E71.0 Maple-syrup-urine disease
0.000 0.525 0.475
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.525 0.475
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.525 0.475
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.525 0.475
E76.2 Other mucopolysaccharidoses
0.000 0.525 0.475
E76.1 Mucopolysaccharidosis, type II
0.000 0.525 0.475
E76.0 Mucopolysaccharidosis, type I
0.000 0.525 0.475
E14.4 With neurological complications
0.000 0.539 0.461
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.549 0.451
E77.1 Defects in glycoprotein degradation
0.000 0.549 0.451
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.549 0.451
E13.3 With ophthalmic complications
0.000 0.553 0.447
E13.8 With unspecified complications
0.000 0.558 0.442
E13.7 With multiple complications
0.000 0.558 0.442
E13.6 With other specified complications
0.000 0.558 0.442
E13.5 With peripheral circulatory complications
0.000 0.558 0.442
E13.4 With neurological complications
0.000 0.558 0.442
E13.2 With renal complications
0.000 0.558 0.442
E13.1 With ketoacidosis
0.000 0.558 0.442
E13.0 With coma
0.000 0.558 0.442
E44.1 Mild protein-energy malnutrition
0.000 0.562 0.438
E44.0 Moderate protein-energy malnutrition
0.000 0.562 0.438
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.574 0.425
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.574 0.425
E72.5 Disorders of glycine metabolism
0.000 0.574 0.425
E72.4 Disorders of ornithine metabolism
0.000 0.574 0.425
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.574 0.425
E72.2 Disorders of urea cycle metabolism
0.000 0.574 0.425
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.574 0.425
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.579 0.421
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.579 0.421
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.579 0.421
E74.2 Disorders of galactose metabolism
0.000 0.579 0.421
E74.1 Disorders of fructose metabolism
0.000 0.579 0.421
E77.8 Other disorders of glycoprotein metabolism
0.000 0.582 0.418
E65 Localised adiposity
0.000 0.589 0.410
E83.5 Disorders of calcium metabolism
0.000 0.593 0.407
E74.0 Glycogen storage disease
0.000 0.594 0.406
E14.2 Withrenal complications
0.000 0.612 0.387
E67 Other hyperalimentation
0.000 0.632 0.368
E68 Sequelae of hyperalimentation
0.000 0.632 0.368
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.633 0.367
E72.0 Disorders of amino-acid transport
0.000 0.643 0.357
E85 Amyloidosis
0.001 0.643 0.356
E13.9 Without complications
0.000 0.651 0.348
K90 Intestinal malabsorption
0.000 0.701 0.299
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.715 0.285
E85.8 Other amyloidosis
0.001 0.736 0.264
E67.8 Other specified hyperalimentation
0.000 0.736 0.264
E67.3 Hypervitaminosis D
0.000 0.736 0.264
E67.2 Megavitamin-B6 syndrome
0.000 0.736 0.264
E67.1 Hypercarotenaemia
0.000 0.736 0.264
E67.0 Hypervitaminosis A
0.000 0.736 0.264
E00-E07 Disorders of thyroid gland
0.000 0.738 0.262
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.744 0.255
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.744 0.255
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.744 0.255
E50-E64 Other nutritional deficiencies
0.001 0.750 0.249
E89.4 Postprocedural ovarian failure
0.000 0.757 0.243
E03 Other hypothyroidism
0.000 0.776 0.224
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.783 0.217
K90.3 Pancreatic steatorrhoea
0.000 0.785 0.215
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.785 0.215
K90.1 Tropical sprue
0.000 0.785 0.215
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.792 0.208
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.796 0.204
E89.1 Postprocedural hypoinsulinaemia
0.000 0.796 0.204
E85.4 Organ-limited amyloidosis
0.001 0.796 0.203
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.800 0.200
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.802 0.198
I10-I15 Hypertensive diseases
0.000 0.804 0.196
K90.9 Intestinal malabsorption, unspecified
0.000 0.806 0.194
E85.9 Amyloidosis, unspecified
0.001 0.808 0.191
E56 Other vitamin deficiencies
0.001 0.811 0.189
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.812 0.188
E00 Congenital iodine-deficiency syndrome
0.000 0.812 0.188
E89.5 Postprocedural testicular hypofunction
0.000 0.814 0.186
K90.8 Other intestinal malabsorption
0.000 0.816 0.183
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.820 0.180
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.821 0.179
E63 Other nutritional deficiencies
0.001 0.821 0.179
E50 Vitamin A deficiency
0.001 0.821 0.179
E60 Dietary zinc deficiency
0.001 0.821 0.179
E59 Dietary selenium deficiency
0.001 0.821 0.179
E54 Ascorbic acid deficiency
0.001 0.821 0.179
E52 Niacin deficiency [pellagra]
0.001 0.821 0.179
E85.3 Secondary systemic amyloidosis
0.001 0.821 0.178
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.825 0.174
E58 Dietary calcium deficiency
0.001 0.825 0.174
E51 Thiamine deficiency
0.001 0.831 0.169
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.832 0.168
E03.8 Other specified hypothyroidism
0.000 0.834 0.166
E03.5 Myxoedema coma
0.000 0.839 0.161
E03.4 Atrophy of thyroid (acquired)
0.000 0.839 0.161
E03.3 Postinfectious hypothyroidism
0.000 0.839 0.161
E03.1 Congenital hypothyroidism without goitre
0.000 0.839 0.160
E05.9 Thyrotoxicosis, unspecified
0.000 0.841 0.159
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.842 0.157
E06 Thyroiditis
0.000 0.844 0.156
E89.3 Postprocedural hypopituitarism
0.000 0.846 0.154
I11 Hypertensive heart disease
0.000 0.847 0.153
E03.9 Hypothyroidism, unspecified
0.000 0.850 0.150
E89.2 Postprocedural hypoparathyroidism
0.000 0.854 0.146
E56.1 Deficiency of vitamin K
0.000 0.854 0.145
E05.8 Other thyrotoxicosis
0.000 0.857 0.143
I13 Hypertensive heart and renal disease
0.000 0.863 0.137
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.863 0.137
E86 Volume depletion
0.000 0.863 0.137
E14.9 Without complications
0.000 0.864 0.136
E56.9 Vitamin deficiency, unspecified
0.001 0.864 0.135
E56.8 Deficiency of other vitamins
0.001 0.864 0.135
E56.0 Deficiency of vitamin E
0.001 0.864 0.135
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.865 0.135
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.865 0.135
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.865 0.135
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.865 0.135
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.865 0.135
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.865 0.135
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.865 0.135
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.865 0.135
E05.5 Thyroid crisis or storm
0.000 0.871 0.129
E05.4 Thyrotoxicosis factitia
0.000 0.871 0.129
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.871 0.129
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.871 0.129
E50.9 Vitamin A deficiency, unspecified
0.001 0.871 0.128
E50.8 Other manifestations of vitamin A deficiency
0.001 0.871 0.128
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.871 0.128
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.871 0.128
E50.5 Vitamin A deficiency with night blindness
0.001 0.871 0.128
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.871 0.128
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.871 0.128
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.871 0.128
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.871 0.128
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.871 0.128
E63.9 Nutritional deficiency, unspecified
0.001 0.871 0.128
E63.8 Other specified nutritional deficiencies
0.001 0.871 0.128
E63.1 Imbalance of constituents of food intake
0.001 0.871 0.128
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.871 0.128
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.871 0.128
E64.8 Sequelae of other nutritional deficiencies
0.001 0.871 0.128
E64.3 Sequelae of rickets
0.001 0.871 0.128
E64.2 Sequelae of vitamin C deficiency
0.001 0.871 0.128
E64.1 Sequelae of vitamin A deficiency
0.001 0.871 0.128
E64.0 Sequelae of protein-energy malnutrition
0.001 0.871 0.128
I15 Secondary hypertension
0.000 0.873 0.127
E53 Deficiency of other B group vitamins
0.000 0.876 0.124
E06.3 Autoimmune thyroiditis
0.000 0.877 0.123
E51.9 Thiamine deficiency, unspecified
0.001 0.878 0.121
E51.8 Other manifestations of thiamine deficiency
0.001 0.878 0.121
E51.1 Beriberi
0.001 0.878 0.121
E07 Other disorders of thyroid
0.000 0.883 0.116
E61 Deficiency of other nutrient elements
0.001 0.884 0.115
E06.4 Drug-induced thyroiditis
0.000 0.888 0.112
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.888 0.112
E06.0 Acute thyroiditis
0.000 0.888 0.112
E51.2 Wernicke's encephalopathy
0.001 0.888 0.111
E55 Vitamin D deficiency
0.001 0.889 0.109
E06.9 Thyroiditis, unspecified
0.000 0.894 0.106
I15.9 Seconday hypertension, unspecified
0.000 0.898 0.102
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.901 0.099
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.901 0.099
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.901 0.099
E06.5 Other chronic thyroiditis
0.000 0.903 0.097
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.905 0.095
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.908 0.092
I15.8 Other secondary hypertension
0.000 0.909 0.091
I15.2 Hypertension secondary to endocrine disorders
0.000 0.911 0.089
E53.1 Pyridoxine deficiency
0.000 0.911 0.089
E53.0 Riboflavin deficiency
0.000 0.911 0.089
E06.1 Subacute thyroiditis
0.000 0.912 0.087
I15.0 Renovascular hypertension
0.000 0.914 0.086
E07.1 Dyshormogenetic goitre
0.000 0.916 0.084
E07.0 Hypersecretion of calcitonin
0.000 0.916 0.084
E61.9 Deficiency of nutrient element, unspecified
0.001 0.917 0.083
E61.8 Deficiency of other specified nutrient elements
0.001 0.917 0.083
E61.7 Deficiency of multiple nutrient elements
0.001 0.917 0.083
E61.6 Vanadium deficiency
0.001 0.917 0.083
E61.5 Molybdenum deficiency
0.001 0.917 0.083
E61.4 Chromium deficiency
0.001 0.917 0.083
E61.3 Manganese deficiency
0.001 0.917 0.083
E61.0 Copper deficiency
0.001 0.917 0.083
E20-E35 Disorders of other endocrine glands
0.000 0.917 0.083
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.919 0.081
E55.0 Rickets, active
0.001 0.920 0.079
E66 Obesity
0.000 0.922 0.078
E53.9 Vitamin B deficiency, unspecified
0.000 0.925 0.075
E61.2 Magnesium deficiency
0.001 0.926 0.074
E07.8 Other specified disorders of thyroid
0.000 0.926 0.074
R40.0 Somnolence
0.069 0.931 0.000
E78.4 Other hyperlipidaemia
0.000 0.933 0.067
E78.1 Pure hyperglyceridaemia
0.000 0.934 0.066
I15.1 Hypertension secondary to other renal disorders
0.000 0.934 0.066
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.934 0.066
E20 Hypoparathyroidism
0.000 0.934 0.066
E89.0 Postprocedural hypothyroidism
0.000 0.935 0.065
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.936 0.064
E25 Adrenogenital disorders
0.000 0.938 0.062
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.939 0.061
E29 Testicular dysfunction
0.000 0.939 0.061
E78.6 Lipoprotein deficiency
0.000 0.940 0.060
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.940 0.060
E32 Diseases of thymus
0.000 0.940 0.060
E31 Polyglandular dysfunction
0.000 0.940 0.060
E30 Disorders of puberty, not elsewhere classified
0.000 0.940 0.060
E53.8 Deficiency of other specified B group vitamins
0.000 0.941 0.059
I83 Varicose veins of lower extremities
0.000 0.941 0.059
E26 Hyperaldosteronism
0.000 0.942 0.058
E66.1 Drug-induced obesity
0.000 0.944 0.056
E78.3 Hyperchylomicronaemia
0.000 0.944 0.056
I12 Hypertensive renal disease
0.000 0.946 0.054
E34 Other endocrine disorders
0.000 0.946 0.054
E20.9 Hypoparathyroidism, unspecified
0.000 0.947 0.053
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.947 0.053
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.947 0.053
E87.5 Hyperkalaemia
0.000 0.951 0.049
E27 Other disorders of adrenal gland
0.000 0.951 0.049
E20.8 Other hypoparathyroidism
0.000 0.953 0.047
E20.1 Pseudohypoparathyroidism
0.000 0.953 0.047
E20.0 Idiopathic hypoparathyroidism
0.000 0.953 0.047
E29.1 Testicular hypofunction
0.000 0.953 0.047
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.953 0.047
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.953 0.047
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.955 0.045
E25.9 Adrenogenital disorder, unspecified
0.000 0.955 0.045
E25.8 Other adrenogenital disorders
0.000 0.955 0.045
E26.9 Hyperaldosteronism, unspecified
0.000 0.956 0.044
E29.8 Other testicular dysfunction
0.000 0.956 0.044
E29.0 Testicular hyperfunction
0.000 0.956 0.044
E34.9 Endocrine disorder, unspecified
0.000 0.956 0.043
E30.9 Disorder of puberty, unspecified
0.000 0.957 0.043
E30.8 Other disorders of puberty
0.000 0.957 0.043
E30.1 Precocious puberty
0.000 0.957 0.043
E30.0 Delayed puberty
0.000 0.957 0.043
E31.9 Polyglandular dysfunction, unspecified
0.000 0.957 0.043
E31.8 Other polyglandular dysfunction
0.000 0.957 0.043
E31.1 Polyglandular hyperfunction
0.000 0.957 0.043
E31.0 Autoimmune polyglandular failure
0.000 0.957 0.043
E32.9 Disease of thymus, unspecified
0.000 0.957 0.043
E32.8 Other diseases of thymus
0.000 0.957 0.043
E32.1 Abscess of thymus
0.000 0.957 0.043
E32.0 Persistent hyperplasia of thymus
0.000 0.957 0.043
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.957 0.043
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.957 0.043
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.957 0.043
D45 Polycythaemia vera
0.000 0.957 0.043
E26.8 Other hyperaldosteronism
0.000 0.958 0.042
E26.1 Secondary hyperaldosteronism
0.000 0.958 0.042
E78.8 Other disorders of lipoprotein metabolism
0.000 0.958 0.042
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.958 0.041
E21.2 Other hyperparathyroidism
0.000 0.959 0.041
E29.9 Testicular dysfunction, unspecified
0.000 0.959 0.041
E61.1 Iron deficiency
0.001 0.960 0.040
E78.2 Mixed hyperlipidaemia
0.000 0.961 0.039
E24 Cushing's syndrome
0.000 0.961 0.039
E28 Ovarian dysfunction
0.000 0.961 0.039
E87.3 Alkalosis
0.000 0.961 0.039
E34.5 Androgen resistance syndrome
0.000 0.961 0.039
E34.4 Constitutional tall stature
0.000 0.961 0.039
E34.3 Short stature, not elsewhere classified
0.000 0.961 0.039
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.961 0.039
E34.1 Other hypersecretion of intestinal hormones
0.000 0.961 0.039
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.961 0.039
E87.4 Mixed disorder of acid-base balance
0.000 0.961 0.038
E34.8 Other specified endocrine disorders
0.000 0.962 0.038
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.962 0.038
E22 Hyperfunction of pituitary gland
0.000 0.962 0.038
E21.4 Other specified disorders of parathyroid gland
0.000 0.962 0.038
E27.1 Primary adrenocortical insufficiency
0.000 0.962 0.038
E26.0 Primary hyperaldosteronism
0.000 0.962 0.037
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.963 0.037
E07.9 Disorder of thyroid, unspecified
0.000 0.964 0.036
E87.0 Hyperosmolality and hypernatraemia
0.000 0.964 0.036
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.964 0.036
E27.5 Adrenomedullary hyperfunction
0.000 0.965 0.035
E27.0 Other adrenocortical overactivity
0.000 0.965 0.035
E66.0 Obesity due to excess calories
0.000 0.966 0.034
E27.2 Addisonian crisis
0.000 0.966 0.033
E27.9 Disorder of adrenal gland, unspecified
0.000 0.969 0.031
E22.1 Hyperprolactinaemia
0.000 0.969 0.030
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.970 0.030
E27.8 Other specified disorders of adrenal gland
0.000 0.970 0.030
E24.2 Drug-induced Cushing's syndrome
0.000 0.971 0.029
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.971 0.028
E24.3 Ectopic ACTH syndrome
0.000 0.971 0.028
E24.1 Nelson's syndrome
0.000 0.971 0.028
E28.9 Ovarian dysfunction, unspecified
0.000 0.972 0.028
E28.8 Other ovarian dysfunction
0.000 0.972 0.028
E28.1 Androgen excess
0.000 0.972 0.028
E28.0 Oestrogen excess
0.000 0.972 0.028
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.972 0.027
E22.8 Other hyperfunction of pituitary gland
0.000 0.972 0.027
E21.0 Primary hyperparathyroidism
0.000 0.972 0.028
E28.3 Primary ovarian failure
0.000 0.974 0.026
E23 Hypofunction and other disorders of pituitary gland
0.000 0.974 0.026
E24.0 Pituitary-dependent Cushing's disease
0.000 0.975 0.025
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.975 0.025
K90-K93 Other diseases of the digestive system
0.000 0.975 0.025
E34.0 Carcinoid syndrome
0.000 0.976 0.024
E24.8 Other Cushing's syndrome
0.000 0.976 0.024
D46 Myelodysplastic syndromes
0.000 0.976 0.024
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.976 0.024
E22.0 Acromegaly and pituitary gigantism
0.000 0.977 0.022
D39.1 Ovary
0.000 0.978 0.022
I12.9 Hypertensive renal disease without renal failure
0.000 0.978 0.022
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.978 0.022
E04 Other non-toxic goitre
0.000 0.978 0.022
E21.3 Hyperparathyroidism, unspecified
0.000 0.978 0.022
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.979 0.021
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.979 0.021
E24.9 Cushing's syndrome, unspecified
0.000 0.979 0.020
D46.4 Refractory anaemia, unspecified
0.000 0.980 0.020
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.980 0.020
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.980 0.020
D44.3 Pituitary gland
0.000 0.980 0.020
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.981 0.018
E23.1 Drug-induced hypopituitarism
0.000 0.981 0.018
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.982 0.018
D46.2 Refractory anaemia with excess of blasts
0.000 0.982 0.018
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.982 0.018
D44.7 Aortic body and other paraganglia
0.000 0.982 0.018
D44.0 Thyroid gland
0.000 0.982 0.018
E66.8 Other obesity
0.000 0.982 0.018
D46.1 Refractory anaemia with sideroblasts
0.000 0.982 0.018
D37.7 Other digestive organs
0.000 0.982 0.018
D39.7 Other female genital organs
0.000 0.982 0.018
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.982 0.018
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.982 0.018
E23.7 Disorder of pituitary gland, unspecified
0.000 0.982 0.018
D37.3 Appendix
0.000 0.982 0.018
D46.7 Other myelodysplastic syndromes
0.000 0.982 0.017
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.983 0.017
D46.5 Refractory anaemia with multi-lineage dysplasia
0.000 0.983 0.017
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.983 0.017
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.983 0.017
D39.0 Uterus
0.000 0.983 0.017
D39.9 Female genital organ, unspecified
0.000 0.983 0.017
D39.2 Placenta
0.000 0.983 0.017
D44.6 Carotid body
0.000 0.983 0.017
D37.6 Liver, gallbladder and bile ducts
0.000 0.983 0.017
E23.2 Diabetes insipidus
0.000 0.984 0.016
D44.5 Pineal gland
0.000 0.984 0.016
D44.2 Parathyroid gland
0.000 0.984 0.016
E04.8 Other specified non-toxic goitre
0.000 0.984 0.016
D37.1 Stomach
0.000 0.984 0.016
D47.2 Monoclonal gammopathy
0.000 0.984 0.016
D37.4 Colon
0.000 0.984 0.016
D37.9 Digestive organ, unspecified
0.000 0.984 0.016
D44.9 Endocrine gland, unspecified
0.000 0.984 0.015
D44.1 Adrenal gland
0.000 0.985 0.015
E23.6 Other disorders of pituitary gland
0.000 0.985 0.015
K70.9 Alcoholic liver disease, unspecified
0.000 0.985 0.015
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.985 0.015
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.985 0.015
D44.8 Pluriglandular involvement
0.000 0.985 0.015
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.985 0.014
D75.1 Secondary polycythaemia
0.000 0.985 0.015
D44.4 Craniopharyngeal duct
0.000 0.986 0.014
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.986 0.014
D42.9 Meninges, unspecified
0.000 0.987 0.013
D42.1 Spinal meninges
0.000 0.987 0.013
D42.0 Cerebral meninges
0.000 0.987 0.013
H57.9 Disorder of eye and adnexa, unspecified
0.013 0.987 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.987 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.987 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.987 0.013
R40 Somnolence, stupor and coma
0.013 0.987 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.987 0.013
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.987 0.013
H57.8 Other specified disorders of eye and adnexa
0.013 0.987 0.000
K70.0 Alcoholic fatty liver
0.000 0.987 0.013
D86.9 Sarcoidosis, unspecified
0.000 0.987 0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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