TreeWAS – Variant ID: rs3135350

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E10.1 With ketoacidosis	1.000	0.000	0.000
H36.0 Diabetic retinopathy	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.000	1.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.000	1.000
H36 Retinal disorders in diseases classified elsewhere	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
E10.4 With neurological complications	1.000	0.000	0.000
K51 Ulcerative colitis	0.000	0.001	0.999
I20-I25 Ischaemic heart diseases	0.999	0.001	0.000
I10-I15 Hypertensive diseases	0.999	0.001	0.000
E14.9 Without complications	0.999	0.001	0.000
K90 Intestinal malabsorption	0.999	0.001	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.001	0.001	0.998
K90-K93 Other diseases of the digestive system	0.998	0.002	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.002	0.998
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.003	0.997
J33 Nasal polyp	0.997	0.003	0.000
J33.9 Nasal polyp, unspecified	0.997	0.003	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.996	0.004	0.000
L40-L45 Papulosquamous disorders	0.995	0.005	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.995	0.005	0.000
K70-K77 Diseases of liver	0.995	0.005	0.000
I10 Essential (primary) hypertension	0.994	0.006	0.000
J45 Asthma	0.994	0.006	0.000
E14.3 With ophthalmic complications	0.994	0.006	0.000
L40 Psoriasis	0.994	0.006	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.007	0.993
Chapter X Diseases of the respiratory system	0.993	0.007	0.000
J40-J47 Chronic lower respiratory diseases	0.993	0.007	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.992	0.008	0.000
L43 Lichen planus	0.992	0.008	0.000
H40-H42 Glaucoma	0.991	0.009	0.000
H43-H45 Disorders of vitreous body and globe	0.991	0.009	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.989	0.011	0.000
E70-E90 Metabolic disorders	0.989	0.011	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.989	0.011	0.000
L43.9 Lichen planus, unspecified	0.988	0.012	0.000
H43 Disorders of vitreous body	0.988	0.012	0.000
Chapter VIII Diseases of the ear and mastoid process	0.988	0.012	0.000
H60-H62 Diseases of external ear	0.985	0.015	0.000
H40 Glaucoma	0.985	0.015	0.000
L40.5 Arthropathic psoriasis	0.984	0.016	0.000
I22 Subsequent myocardial infarction	0.983	0.017	0.000
H40.9 Glaucoma, unspecified	0.982	0.018	0.000
J30-J39 Other diseases of upper respiratory tract	0.980	0.020	0.000
E05.9 Thyrotoxicosis, unspecified	0.979	0.021	0.000
E10.5 With peripheral circulatory complications	0.977	0.023	0.000
K74 Fibrosis and cirrhosis of liver	0.974	0.026	0.000
H61 Other disorders of external ear	0.973	0.027	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.972	0.028	0.000
E11.3 With ophthalmic complications	0.965	0.035	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.965	0.035	0.000
E06 Thyroiditis	0.964	0.036	0.000
J33.8 Other polyp of sinus	0.963	0.037	0.000
I20 Angina pectoris	0.962	0.038	0.000
K51.8 Other ulcerative colitis	0.000	0.039	0.961
E11.1 With ketoacidosis	0.961	0.039	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.959	0.041	0.000
I12 Hypertensive renal disease	0.959	0.041	0.000
H43.8 Other disorders of vitreous body	0.957	0.043	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.957	0.043	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.955	0.045	0.000
H43.3 Other vitreous opacities	0.954	0.046	0.000
K50-K52 Noninfective enteritis and colitis	0.934	0.052	0.013
K74.3 Primary biliary cirrhosis	0.947	0.053	0.000
J33.0 Polyp of nasal cavity	0.946	0.054	0.000
H61.0 Perichondritis of external ear	0.944	0.056	0.000
H60 Otitis externa	0.941	0.059	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.936	0.064	0.000
E06.3 Autoimmune thyroiditis	0.936	0.064	0.000
I25 Chronic ischaemic heart disease	0.929	0.071	0.000
M70-M79 Other soft tissue disorders	0.926	0.074	0.000
E10.2 With renal complications	0.925	0.075	0.000
K55-K64 Other diseases of intestines	0.921	0.079	0.000
H34 Retinal vascular occlusions	0.921	0.079	0.000
M65-M68 Disorders of synovium and tendon	0.919	0.081	0.000
I15 Secondary hypertension	0.918	0.082	0.000
K72 Hepatic failure, not elsewhere classified	0.918	0.082	0.000
L40.9 Psoriasis, unspecified	0.918	0.082	0.000
E10.8 With unspecified complications	0.916	0.084	0.000
E11.5 With peripheral circulatory complications	0.915	0.085	0.000
E13 Other specified diabetes mellitus	0.914	0.086	0.000
J46 Status asthmaticus	0.908	0.092	0.000
K60 Fissure and fistula of anal and rectal regions	0.908	0.092	0.000
Q80-Q89 Other congenital malformations	0.906	0.094	0.000
M06.0 Seronegative rheumatoid arthritis	0.904	0.096	0.000
E10.0 With coma	0.904	0.096	0.000
Q60-Q64 Congenital malformations of the urinary system	0.902	0.098	0.000
I12.9 Hypertensive renal disease without renal failure	0.902	0.098	0.000
M07 Psoriatic and enteropathic arthropathies	0.901	0.099	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.100	0.900
E11.2 With renal complications	0.893	0.107	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.890	0.110	0.000
I20.1 Angina pectoris with documented spasm	0.889	0.111	0.000
K50 Crohn's disease [regional enteritis]	0.889	0.111	0.001
M75 Shoulder lesions	0.888	0.112	0.000
M06.3 Rheumatoid nodule	0.879	0.121	0.000
E03.8 Other specified hypothyroidism	0.877	0.123	0.000
I20.9 Angina pectoris, unspecified	0.876	0.124	0.000
I24 Other acute ischaemic heart diseases	0.876	0.124	0.000
M06.4 Inflammatory polyarthropathy	0.875	0.125	0.000
J86 Pyothorax	0.874	0.126	0.000
E07 Other disorders of thyroid	0.873	0.127	0.000
I25.5 Ischaemic cardiomyopathy	0.871	0.129	0.000
Q61 Cystic kidney disease	0.870	0.130	0.000
K58 Irritable bowel syndrome	0.870	0.130	0.000
M75.0 Adhesive capsulitis of shoulder	0.868	0.132	0.000
H40.1 Primary open-angle glaucoma	0.867	0.133	0.000
M77 Other enthesopathies	0.867	0.133	0.000
M65 Synovitis and tenosynovitis	0.863	0.137	0.000
I20.0 Unstable angina	0.862	0.138	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.860	0.140	0.000
K73 Chronic hepatitis, not elsewhere classified	0.858	0.142	0.000
K75 Other inflammatory liver diseases	0.858	0.142	0.000
K60.2 Anal fissure, unspecified	0.857	0.143	0.000
M77.1 Lateral epicondylitis	0.854	0.146	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.853	0.147	0.000
K60.0 Acute anal fissure	0.852	0.148	0.000
E11.6 With other specified complications	0.850	0.150	0.000
Q85 Phakomatoses, not elsewhere classified	0.850	0.150	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.848	0.152	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.847	0.153	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.847	0.153	0.000
H25-H28 Disorders of lens	0.845	0.155	0.000
E13.9 Without complications	0.843	0.157	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.842	0.158	0.000
M07.3 Other psoriatic arthropathies	0.840	0.160	0.000
H61.8 Other specified disorders of external ear	0.835	0.165	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.166	0.834
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.834	0.166	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.830	0.170	0.000
K60.5 Anorectal fistula	0.830	0.170	0.000
H60.3 Other infective otitis externa	0.830	0.170	0.000
H40.5 Glaucoma secondary to other eye disorders	0.830	0.170	0.000
E10.6 With other specified complications	0.829	0.171	0.000
K55 Vascular disorders of intestine	0.829	0.171	0.000
H61.1 Non-infective disorders of pinna	0.828	0.172	0.000
I12.0 Hypertensive renal disease with renal failure	0.822	0.178	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.821	0.179	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.820	0.180	0.000
E14.1 With ketoacidosis	0.819	0.181	0.000
K74.6 Other and unspecified cirrhosis of liver	0.819	0.181	0.000
I15.1 Hypertension secondary to other renal disorders	0.817	0.183	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.185	0.815
I25.2 Old myocardial infarction	0.814	0.186	0.000
E78.1 Pure hyperglyceridaemia	0.814	0.186	0.000
K74.5 Biliary cirrhosis, unspecified	0.814	0.186	0.000
E88 Other metabolic disorders	0.813	0.187	0.000
K50.8 Other Crohn's disease	0.813	0.187	0.000
K51.4 Pseudopolyposis of colon	0.000	0.190	0.810
K72.9 Hepatic failure, unspecified	0.809	0.191	0.000
K75.4 Autoimmune hepatitis	0.809	0.191	0.000
H40.3 Glaucoma secondary to eye trauma	0.809	0.191	0.000
E14.6 With other specified complications	0.808	0.192	0.000
E14.4 With neurological complications	0.807	0.193	0.000
H34.2 Other retinal artery occlusions	0.806	0.194	0.000
H60.9 Otitis externa, unspecified	0.803	0.197	0.000
Q61.3 Polycystic kidney, unspecified	0.803	0.197	0.000
Q50-Q56 Congenital malformations of genital organs	0.802	0.198	0.000
K71 Toxic liver disease	0.801	0.199	0.000
M45-M49 Spondylopathies	0.800	0.200	0.000
E14.8 With unspecified complications	0.799	0.201	0.000
E40-E46 Malnutrition	0.798	0.202	0.000
J43 Emphysema	0.795	0.204	0.000
E07.9 Disorder of thyroid, unspecified	0.794	0.206	0.000
M14 Arthropathies in other diseases classified elsewhere	0.793	0.206	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.793	0.207	0.000
M08 Juvenile arthritis	0.792	0.208	0.000
L43.8 Other lichen planus	0.792	0.208	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.791	0.209	0.000
M75.2 Bicipital tendinitis	0.791	0.209	0.000
H27 Other disorders of lens	0.788	0.212	0.000
J86.9 Pyothorax without fistula	0.788	0.212	0.000
K50.1 Crohn's disease of large intestine	0.788	0.212	0.000
K63 Other diseases of intestine	0.786	0.214	0.000
J33.1 Polypoid sinus degeneration	0.786	0.214	0.000
M45 Ankylosing spondylitis	0.785	0.215	0.000
J44 Other chronic obstructive pulmonary disease	0.783	0.217	0.000
E16.1 Other hypoglycaemia	0.782	0.218	0.000
J37 Chronic laryngitis and laryngotracheitis	0.781	0.219	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.779	0.221	0.000
L40.4 Guttate psoriasis	0.779	0.221	0.000
I23 Certain current complications following acute myocardial infarction	0.778	0.222	0.000
H61.3 Acquired stenosis of external ear canal	0.777	0.223	0.000
E78.2 Mixed hyperlipidaemia	0.776	0.224	0.000
Q61.0 Congenital single renal cyst	0.776	0.224	0.000
E10.7 With multiple complications	0.775	0.225	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.774	0.226	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.773	0.227	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.773	0.227	0.000
E14.5 With peripheral circulatory complications	0.770	0.229	0.000
L40.1 Generalised pustular psoriasis	0.770	0.230	0.000
E11.7 With multiple complications	0.770	0.230	0.000
M05.8 Other seropositive rheumatoid arthritis	0.769	0.231	0.000
E78.5 Hyperlipidaemia, unspecified	0.769	0.231	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.768	0.232	0.000
M60-M63 Disorders of muscles	0.766	0.234	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.766	0.234	0.000
H60.4 Cholesteatoma of external ear	0.766	0.234	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.765	0.235	0.000
E74 Other disorders of carbohydrate metabolism	0.765	0.235	0.000
J32 Chronic sinusitis	0.764	0.236	0.000
K51.5 Mucosal proctocolitis	0.000	0.236	0.764
H34.8 Other retinal vascular occlusions	0.764	0.236	0.000
L10-L14 Bullous disorders	0.762	0.237	0.000
J85 Abscess of lung and mediastinum	0.762	0.238	0.000
Q83 Congenital malformations of breast	0.760	0.240	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.760	0.240	0.000
K63.9 Disease of intestine, unspecified	0.759	0.241	0.000
E14.2 Withrenal complications	0.759	0.241	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.757	0.243	0.000
K72.0 Acute and subacute hepatic failure	0.757	0.243	0.000
L40.8 Other psoriasis	0.755	0.245	0.000
H43.9 Disorder of vitreous body, unspecified	0.755	0.245	0.000
E06.5 Other chronic thyroiditis	0.753	0.247	0.000
H43.0 Vitreous prolapse	0.753	0.247	0.000
K55.2 Angiodysplasia of colon	0.750	0.250	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.748	0.252	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.746	0.254	0.000
M11 Other crystal arthropathies	0.746	0.254	0.000
J86.0 Pyothorax with fistula	0.745	0.255	0.000
I15.9 Seconday hypertension, unspecified	0.745	0.255	0.000
H43.2 Crystalline deposits in vitreous body	0.745	0.255	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.745	0.255	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.743	0.257	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.741	0.259	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.741	0.259	0.000
L44 Other papulosquamous disorders	0.741	0.259	0.000
M05.1 Rheumatoid lung disease	0.739	0.261	0.000
K90.9 Intestinal malabsorption, unspecified	0.738	0.261	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.738	0.262	0.000
Q85.9 Phakomatosis, unspecified	0.738	0.262	0.000
L40.3 Pustulosis palmaris et plantaris	0.737	0.263	0.000
E70 Disorders of aromatic amino-acid metabolism	0.733	0.267	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.733	0.267	0.000
I25.1 Atherosclerotic heart disease	0.733	0.267	0.000
L43.0 Hypertrophic lichen planus	0.732	0.268	0.000
M06.8 Other specified rheumatoid arthritis	0.732	0.268	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.732	0.268	0.000
M75.4 Impingement syndrome of shoulder	0.731	0.269	0.000
E11.8 With unspecified complications	0.729	0.270	0.000
H60.5 Acute otitis externa, non-infective	0.729	0.271	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.727	0.273	0.000
M75.3 Calcific tendinitis of shoulder	0.727	0.273	0.000
H40.4 Glaucoma secondary to eye inflammation	0.726	0.274	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.726	0.274	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.725	0.275	0.000
K52 Other non-infective gastro-enteritis and colitis	0.722	0.276	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.722	0.278	0.000
E78.6 Lipoprotein deficiency	0.721	0.279	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.721	0.279	0.000
H34.1 Central retinal artery occlusion	0.720	0.280	0.000
E77 Disorders of glycoprotein metabolism	0.719	0.281	0.000
Q89 Other congenital malformations, not elsewhere classified	0.718	0.281	0.000
E14.0 With coma	0.718	0.282	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
K90.3 Pancreatic steatorrhoea	0.716	0.284	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.716	0.284	0.000
K90.1 Tropical sprue	0.716	0.284	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.716	0.284	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.284	0.715
G37.4 Subacute necrotising myelitis	0.000	0.284	0.715
G37.2 Central pontine myelinolysis	0.000	0.284	0.715
G37.1 Central demyelination of corpus callosum	0.000	0.284	0.715
G37.0 Diffuse sclerosis	0.000	0.284	0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.715	0.285	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.715	0.285	0.000
I11 Hypertensive heart disease	0.715	0.285	0.000
I15.2 Hypertension secondary to endocrine disorders	0.715	0.285	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.715	0.285	0.000
H60.8 Other otitis externa	0.714	0.286	0.000
J45.1 Nonallergic asthma	0.714	0.286	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.714	0.286	0.000
K55.8 Other vascular disorders of intestine	0.713	0.287	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.713	0.287	0.000
L40.2 Acrodermatitis continua	0.712	0.287	0.000
M06.34 Rheumatoid nodule (Hand)	0.712	0.288	0.000
H65-H75 Diseases of middle ear and mastoid	0.712	0.288	0.000
L43.3 Subacute (active) lichen planus	0.711	0.289	0.000
L43.2 Lichenoid drug reaction	0.711	0.289	0.000
L43.1 Bullous lichen planus	0.711	0.289	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.711	0.289	0.000
H42 Glaucoma in diseases classified elsewhere	0.710	0.289	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.710	0.290	0.000
M05.0 Felty's syndrome	0.710	0.290	0.000
E76 Disorders of glycosaminoglycan metabolism	0.709	0.290	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.709	0.290	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.709	0.290	0.000
H60.2 Malignant otitis externa	0.709	0.291	0.000
E05.5 Thyroid crisis or storm	0.709	0.291	0.000
E05.4 Thyrotoxicosis factitia	0.709	0.291	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.709	0.291	0.000
K73.9 Chronic hepatitis, unspecified	0.709	0.291	0.000
G36 Other acute disseminated demyelination	0.001	0.292	0.707
K63.3 Ulcer of intestine	0.707	0.293	0.000
K72.1 Chronic hepatic failure	0.707	0.293	0.000
E11.0 With coma	0.703	0.297	0.000
M06.1 Adult-onset Still's disease	0.703	0.297	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.701	0.299	0.000
M80-M85 Disorders of bone density and structure	0.701	0.299	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.299	0.701
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.700	0.300	0.000
L40.0 Psoriasis vulgaris	0.700	0.300	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.699	0.301	0.000
K74.4 Secondary biliary cirrhosis	0.698	0.302	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.698	0.302	0.000
H40.6 Glaucoma secondary to drugs	0.697	0.303	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.696	0.304	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.695	0.305	0.000
H43.1 Vitreous haemorrhage	0.695	0.305	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.694	0.306	0.000
E06.4 Drug-induced thyroiditis	0.691	0.309	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.691	0.309	0.000
E06.0 Acute thyroiditis	0.691	0.309	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.690	0.310	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.690	0.310	0.000
J41 Simple and mucopurulent chronic bronchitis	0.689	0.311	0.000
E13.3 With ophthalmic complications	0.689	0.311	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.689	0.311	0.000
E11.4 With neurological complications	0.688	0.312	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.688	0.312	0.000
I00-I02 Acute rheumatic fever	0.685	0.315	0.000
I25.6 Silent myocardial ischaemia	0.684	0.316	0.000
H27.0 Aphakia	0.684	0.316	0.000
K77 Liver disorders in diseases classified elsewhere	0.684	0.316	0.000
Q35-Q37 Cleft lip and cleft palate	0.683	0.317	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.683	0.317	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.681	0.319	0.000
I15.0 Renovascular hypertension	0.680	0.319	0.000
E05.8 Other thyrotoxicosis	0.679	0.320	0.000
K50.0 Crohn's disease of small intestine	0.679	0.320	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.679	0.321	0.000
M14.6 Neuropathic arthropathy	0.679	0.321	0.000
M60 Myositis	0.678	0.322	0.000
I25.4 Coronary artery aneurysm	0.677	0.323	0.000
E72 Other disorders of amino-acid metabolism	0.677	0.323	0.000
Q82 Other congenital malformations of skin	0.676	0.324	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.675	0.325	0.000
H30 Chorioretinal inflammation	0.675	0.325	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.326	0.674
Q61.2 Polycystic kidney, adult type	0.671	0.329	0.000
L41 Parapsoriasis	0.671	0.329	0.000
E06.9 Thyroiditis, unspecified	0.669	0.331	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.669	0.331	0.000
H60.1 Cellulitis of external ear	0.667	0.332	0.000
H27.8 Other specified disorders of lens	0.667	0.333	0.000
J45.8 Mixed asthma	0.666	0.334	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.665	0.334	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.665	0.335	0.000
H61.9 Disorder of external ear, unspecified	0.664	0.336	0.000
M66 Spontaneous rupture of synovium and tendon	0.664	0.336	0.000
I21 Acute myocardial infarction	0.664	0.336	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.664	0.336	0.000
E78.3 Hyperchylomicronaemia	0.663	0.336	0.000
M77.3 Calcaneal spur	0.663	0.337	0.000
J95-J99 Other diseases of the respiratory system	0.663	0.337	0.000
I13 Hypertensive heart and renal disease	0.662	0.338	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.662	0.338	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.661	0.339	0.000
K64 Haemorrhoids and perianal venous thrombosis	0.660	0.339	0.000
H34.0 Transient retinal artery occlusion	0.660	0.340	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.659	0.341	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.658	0.342	0.000
E06.1 Subacute thyroiditis	0.656	0.344	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.656	0.344	0.000
K63.4 Enteroptosis	0.656	0.344	0.000
E13.8 With unspecified complications	0.655	0.345	0.000
E13.7 With multiple complications	0.655	0.345	0.000
E13.6 With other specified complications	0.655	0.345	0.000
E13.5 With peripheral circulatory complications	0.655	0.345	0.000
E13.4 With neurological complications	0.655	0.345	0.000
E13.2 With renal complications	0.655	0.345	0.000
E13.1 With ketoacidosis	0.655	0.345	0.000
E13.0 With coma	0.655	0.345	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.655	0.345	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.655	0.345	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.655	0.345	0.000
K52.1 Toxic gastro-enteritis and colitis	0.654	0.346	0.001
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.654	0.346	0.000
E46 Unspecified protein-energy malnutrition	0.654	0.346	0.000
Chapter VI Diseases of the nervous system	0.636	0.347	0.017
E83 Disorders of mineral metabolism	0.179	0.347	0.474
L42 Pityriasis rosea	0.651	0.349	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.651	0.349	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.650	0.350	0.000
Q84 Other congenital malformations of integument	0.650	0.350	0.000
Q81 Epidermolysis bullosa	0.650	0.350	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.648	0.352	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.648	0.352	0.000
H25 Senile cataract	0.648	0.352	0.000
M07.5 Arthropathy in ulcerative colitis	0.646	0.354	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.646	0.354	0.000
M07.2 Psoriatic spondylitis	0.646	0.354	0.000
M07.1 Arthritis mutilans	0.646	0.354	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.646	0.354	0.000
J32.4 Chronic pansinusitis	0.644	0.356	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.644	0.356	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.644	0.356	0.000
Q54 Hypospadias	0.643	0.357	0.000
Q80 Congenital ichthyosis	0.643	0.357	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.642	0.358	0.000
H34.9 Retinal vascular occlusion, unspecified	0.642	0.358	0.000
M67 Other disorders of synovium and tendon	0.642	0.358	0.000
E03.1 Congenital hypothyroidism without goitre	0.642	0.358	0.000
M82 Osteoporosis in diseases classified elsewhere	0.641	0.359	0.000
M15-M19 Arthrosis	0.641	0.359	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.641	0.359	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.641	0.359	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.640	0.360	0.000
J37.0 Chronic laryngitis	0.638	0.362	0.000
E79 Disorders of purine and pyrimidine metabolism	0.636	0.363	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.636	0.364	0.000
M05.2 Rheumatoid vasculitis	0.636	0.364	0.000
H25.1 Senile nuclear cataract	0.636	0.364	0.000
M76 Enthesopathies of lower limb, excluding foot	0.635	0.365	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.635	0.365	0.000
M12 Other specific arthropathies	0.635	0.365	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.632	0.368	0.000
K71.0 Toxic liver disease with cholestasis	0.632	0.368	0.000
Q61.5 Medullary cystic kidney	0.630	0.370	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.630	0.370	0.000
M06.38 Rheumatoid nodule (Other)	0.630	0.370	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.630	0.370	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.630	0.370	0.000
M06.33 Rheumatoid nodule (Forearm)	0.630	0.370	0.000
Q83.1 Accessory breast	0.629	0.371	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.629	0.371	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.628	0.372	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.627	0.373	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.627	0.373	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.627	0.373	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.627	0.373	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.627	0.373	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.627	0.373	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.627	0.373	0.000
H27.1 Dislocation of lens	0.627	0.373	0.000
E88.2 Lipomatosis, not elsewhere classified	0.626	0.374	0.000
J43.2 Centrilobular emphysema	0.626	0.374	0.000
K55.1 Chronic vascular disorders of intestine	0.626	0.374	0.000
K75.9 Inflammatory liver disease, unspecified	0.626	0.374	0.000
E07.1 Dyshormogenetic goitre	0.626	0.374	0.000
E07.0 Hypersecretion of calcitonin	0.626	0.374	0.000
J43.9 Emphysema, unspecified	0.625	0.375	0.000
K74.1 Hepatic sclerosis	0.625	0.375	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.624	0.375	0.000
Q61.8 Other cystic kidney diseases	0.624	0.376	0.000
Q61.1 Polycystic kidney, infantile type	0.624	0.376	0.000
E88.9 Metabolic disorder, unspecified	0.624	0.376	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.621	0.377	0.002
E78.8 Other disorders of lipoprotein metabolism	0.622	0.377	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.622	0.378	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations