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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3763365
log Bayes Factor = 87.8968
Chromosome 6   position 32,807,453  (GRCh37) Explore rs3763365 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.998 0.002 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.998 0.002 0.000
E11.9 Without complications
0.998 0.002 0.000
E16 Other disorders of pancreatic internal secretion
0.997 0.003 0.000
E16.2 Hypoglycaemia, unspecified
0.997 0.003 0.000
E14 Unspecified diabetes mellitus
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
E10.4 With neurological complications
0.994 0.006 0.000
M05 Seropositive rheumatoid arthritis
0.993 0.007 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.991 0.009 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.987 0.013 0.000
E11.3 With ophthalmic complications
0.981 0.019 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.974 0.026 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.973 0.027 0.000
E11.2 With renal complications
0.970 0.030 0.000
E14.3 With ophthalmic complications
0.969 0.031 0.000
E10.2 With renal complications
0.960 0.040 0.000
E10.8 With unspecified complications
0.959 0.041 0.000
E06 Thyroiditis
0.945 0.055 0.000
E10.0 With coma
0.931 0.069 0.000
M06.3 Rheumatoid nodule
0.926 0.074 0.000
E20-E35 Disorders of other endocrine glands
0.899 0.101 0.000
E06.3 Autoimmune thyroiditis
0.882 0.118 0.000
E11.1 With ketoacidosis
0.879 0.121 0.000
E11.4 With neurological complications
0.876 0.124 0.000
E10.6 With other specified complications
0.875 0.125 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.874 0.126 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.862 0.138 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.858 0.142 0.000
E11.6 With other specified complications
0.852 0.148 0.000
E27 Other disorders of adrenal gland
0.839 0.161 0.000
E10.7 With multiple complications
0.834 0.166 0.000
E23 Hypofunction and other disorders of pituitary gland
0.834 0.166 0.000
M05.8 Other seropositive rheumatoid arthritis
0.833 0.167 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.832 0.168 0.000
E14.9 Without complications
0.830 0.170 0.000
E27.1 Primary adrenocortical insufficiency
0.829 0.171 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.829 0.171 0.000
E14.6 With other specified complications
0.823 0.177 0.000
E14.1 With ketoacidosis
0.821 0.179 0.000
M06.4 Inflammatory polyarthropathy
0.818 0.182 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.813 0.187 0.000
E10.5 With peripheral circulatory complications
0.801 0.199 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.800 0.200 0.000
E14.8 With unspecified complications
0.798 0.202 0.000
E11.8 With unspecified complications
0.794 0.205 0.000
M10 Gout
0.794 0.206 0.000
M05.0 Felty's syndrome
0.791 0.209 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.788 0.212 0.000
M14 Arthropathies in other diseases classified elsewhere
0.775 0.224 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.774 0.226 0.000
M08 Juvenile arthritis
0.768 0.232 0.000
E11.7 With multiple complications
0.766 0.234 0.000
E06.5 Other chronic thyroiditis
0.765 0.235 0.000
E14.0 With coma
0.762 0.238 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.754 0.245 0.000
E23.7 Disorder of pituitary gland, unspecified
0.754 0.246 0.000
E14.5 With peripheral circulatory complications
0.750 0.250 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.750 0.250 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.749 0.250 0.000
M05.1 Rheumatoid lung disease
0.747 0.253 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.741 0.259 0.000
E23.2 Diabetes insipidus
0.741 0.259 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.737 0.263 0.000
H36.0 Diabetic retinopathy
0.733 0.267 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.733 0.267 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.732 0.268 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.730 0.270 0.000
M06.8 Other specified rheumatoid arthritis
0.729 0.270 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.715 0.285 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.715 0.285 0.000
E16.4 Abnormal secretion of gastrin
0.715 0.285 0.000
E16.3 Increased secretion of glucagon
0.715 0.285 0.000
E14.7 With multiple complications
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.712 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.712 0.288 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.710 0.289 0.000
E03.1 Congenital hypothyroidism without goitre
0.704 0.296 0.000
M12 Other specific arthropathies
0.703 0.297 0.000
E06.9 Thyroiditis, unspecified
0.702 0.298 0.000
E11.5 With peripheral circulatory complications
0.701 0.299 0.000
M06.0 Seronegative rheumatoid arthritis
0.700 0.300 0.000
E13 Other specified diabetes mellitus
0.697 0.303 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.693 0.307 0.000
E14.4 With neurological complications
0.683 0.316 0.000
E24 Cushing's syndrome
0.683 0.317 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.680 0.320 0.000
M06.34 Rheumatoid nodule (Hand)
0.679 0.321 0.000
E06.4 Drug-induced thyroiditis
0.677 0.323 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.677 0.323 0.000
E06.0 Acute thyroiditis
0.677 0.323 0.000
E06.1 Subacute thyroiditis
0.667 0.333 0.000
E20 Hypoparathyroidism
0.666 0.334 0.000
E14.2 Withrenal complications
0.666 0.334 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.334 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.664 0.336 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.664 0.336 0.000
M06.38 Rheumatoid nodule (Other)
0.664 0.336 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.664 0.336 0.000
M06.33 Rheumatoid nodule (Forearm)
0.664 0.336 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.664 0.336 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.662 0.338 0.000
M05.2 Rheumatoid vasculitis
0.657 0.343 0.000
E23.6 Other disorders of pituitary gland
0.654 0.346 0.000
M13 Other arthritis
0.653 0.347 0.000
E27.8 Other specified disorders of adrenal gland
0.651 0.349 0.000
E03.8 Other specified hypothyroidism
0.647 0.353 0.000
M05.09 Felty's syndrome (Site unspecified)
0.646 0.354 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.645 0.355 0.000
E32 Diseases of thymus
0.645 0.355 0.000
E30 Disorders of puberty, not elsewhere classified
0.645 0.355 0.000
E29 Testicular dysfunction
0.642 0.358 0.000
M14.6 Neuropathic arthropathy
0.642 0.358 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.640 0.359 0.000
E31 Polyglandular dysfunction
0.638 0.362 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.638 0.362 0.000
M10.0 Idiopathic gout
0.636 0.364 0.000
E25 Adrenogenital disorders
0.636 0.364 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.625 0.375 0.000
M11 Other crystal arthropathies
0.620 0.380 0.000
E16.1 Other hypoglycaemia
0.618 0.381 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.616 0.384 0.000
E04 Other non-toxic goitre
0.609 0.391 0.000
M08.0 Juvenile rheumatoid arthritis
0.606 0.394 0.000
E27.5 Adrenomedullary hyperfunction
0.602 0.398 0.000
E27.0 Other adrenocortical overactivity
0.602 0.398 0.000
E23.1 Drug-induced hypopituitarism
0.598 0.402 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.597 0.403 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.597 0.403 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.597 0.403 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.597 0.403 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.597 0.403 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.597 0.403 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.597 0.403 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.597 0.403 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.595 0.405 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.593 0.407 0.000
M10.9 Gout, unspecified
0.589 0.411 0.000
E28 Ovarian dysfunction
0.589 0.411 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.587 0.413 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.587 0.413 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.587 0.413 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.587 0.413 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.587 0.413 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.587 0.413 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.587 0.413 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.586 0.414 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.582 0.418 0.000
M13.8 Other specified arthritis
0.581 0.419 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.578 0.422 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.571 0.429 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.570 0.429 0.000
M10.4 Other secondary gout
0.569 0.431 0.000
M10.3 Gout due to impairment of renal function
0.569 0.431 0.000
M10.2 Drug-induced gout
0.569 0.431 0.000
M10.1 Lead-induced gout
0.569 0.431 0.000
M05.08 Felty's syndrome (Other)
0.567 0.433 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.567 0.433 0.000
M05.06 Felty's syndrome (Lower leg)
0.567 0.433 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.567 0.433 0.000
M05.04 Felty's syndrome (Hand)
0.567 0.433 0.000
M05.03 Felty's syndrome (Forearm)
0.567 0.433 0.000
M05.02 Felty's syndrome (Upper arm)
0.567 0.433 0.000
M05.01 Felty's syndrome (Shoulder region)
0.567 0.433 0.000
M05.00 Felty's syndrome (Multiple sites)
0.567 0.433 0.000
E05.8 Other thyrotoxicosis
0.566 0.434 0.000
M07 Psoriatic and enteropathic arthropathies
0.562 0.438 0.000
M14.4 Arthropathy in amyloidosis
0.556 0.444 0.000
M14.3 Lipoid dermatoarthritis
0.556 0.444 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.556 0.444 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.556 0.444 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.556 0.444 0.000
M08.9 Juvenile arthritis, unspecified
0.551 0.449 0.000
M08.8 Other juvenile arthritis
0.551 0.449 0.000
M08.4 Pauciarticular juvenile arthritis
0.551 0.449 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.551 0.449 0.000
M08.2 Juvenile arthritis with systemic onset
0.551 0.449 0.000
M08.1 Juvenile ankylosing spondylitis
0.551 0.449 0.000
E24.2 Drug-induced Cushing's syndrome
0.547 0.453 0.000
M14.2 Diabetic arthropathy
0.546 0.454 0.000
E04.0 Non-toxic diffuse goitre
0.544 0.456 0.000
M12.3 Palindromic rheumatism
0.544 0.456 0.000
M10.96 Gout, unspecified (Lower leg)
0.544 0.456 0.000
E24.8 Other Cushing's syndrome
0.540 0.460 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.537 0.463 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.536 0.463 0.000
M05.18 Rheumatoid lung disease (Other)
0.536 0.464 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.536 0.464 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.536 0.464 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.536 0.464 0.000
M05.14 Rheumatoid lung disease (Hand)
0.536 0.464 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.536 0.464 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.536 0.464 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.536 0.464 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.536 0.464 0.000
E40-E46 Malnutrition
0.530 0.470 0.000
E13.3 With ophthalmic complications
0.530 0.470 0.000
M12.5 Traumatic arthropathy
0.528 0.472 0.000
E07 Other disorders of thyroid
0.527 0.473 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.523 0.477 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.523 0.477 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.523 0.477 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.523 0.477 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.523 0.477 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.523 0.477 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.523 0.477 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.523 0.477 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.523 0.477 0.000
M10.90 Gout, unspecified (Multiple sites)
0.519 0.481 0.000
M10.06 Idiopathic gout (Lower leg)
0.516 0.484 0.000
E26 Hyperaldosteronism
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.513 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.513 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.513 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.513 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.513 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.513 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.513 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.513 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.513 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.513 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.513 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.513 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.513 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.513 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.513 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.513 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.513 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.513 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.513 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.513 0.486 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.512 0.487 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.511 0.489 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.511 0.489 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.511 0.489 0.000
M09.0 Juvenile arthritis in psoriasis
0.511 0.489 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.510 0.489 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.510 0.489 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.510 0.489 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.510 0.489 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.510 0.489 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.510 0.489 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.510 0.489 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.510 0.489 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.510 0.489 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.510 0.489 0.000
E34 Other endocrine disorders
0.505 0.494 0.000
M12.4 Intermittent hydrarthrosis
0.504 0.496 0.000
M12.1 Kaschin-Beck disease
0.504 0.496 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.504 0.496 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.502 0.498 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.502 0.498 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.502 0.498 0.000
E13.8 With unspecified complications
0.500 0.500 0.000
E13.7 With multiple complications
0.500 0.500 0.000
E13.6 With other specified complications
0.500 0.500 0.000
E13.5 With peripheral circulatory complications
0.500 0.500 0.000
E13.4 With neurological complications
0.500 0.500 0.000
E13.2 With renal complications
0.500 0.500 0.000
E13.1 With ketoacidosis
0.500 0.500 0.000
E13.0 With coma
0.500 0.500 0.000
E20.9 Hypoparathyroidism, unspecified
0.500 0.500 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.496 0.504 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.495 0.505 0.000
E24.0 Pituitary-dependent Cushing's disease
0.495 0.505 0.000
E22 Hyperfunction of pituitary gland
0.493 0.507 0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.493 0.507 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.490 0.510 0.000
E24.3 Ectopic ACTH syndrome
0.490 0.510 0.000
E24.1 Nelson's syndrome
0.490 0.510 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.488 0.512 0.000
E27.2 Addisonian crisis
0.485 0.514 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.484 0.516 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.483 0.517 0.000
M35.3 Polymyalgia rheumatica
0.480 0.520 0.000
M13.80 Other specified arthritis (Multiple sites)
0.480 0.520 0.000
M13.0 Polyarthritis, unspecified
0.478 0.522 0.000
E20.8 Other hypoparathyroidism
0.478 0.522 0.000
E20.1 Pseudohypoparathyroidism
0.478 0.522 0.000
E20.0 Idiopathic hypoparathyroidism
0.478 0.522 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.476 0.524 0.000
M13.89 Other specified arthritis (Site unspecified)
0.475 0.525 0.000
M05.28 Rheumatoid vasculitis (Other)
0.471 0.529 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.471 0.529 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.471 0.529 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.471 0.529 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.471 0.529 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.471 0.529 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.471 0.529 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.471 0.529 0.000
E11.0 With coma
0.470 0.530 0.000
M13.1 Monoarthritis, not elsewhere classified
0.468 0.532 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.464 0.536 0.000
M11.9 Crystal arthropathy, unspecified
0.463 0.537 0.000
E50-E64 Other nutritional deficiencies
0.462 0.537 0.000
E30.9 Disorder of puberty, unspecified
0.462 0.538 0.000
E30.8 Other disorders of puberty
0.462 0.538 0.000
E30.1 Precocious puberty
0.462 0.538 0.000
E30.0 Delayed puberty
0.462 0.538 0.000
E32.9 Disease of thymus, unspecified
0.462 0.538 0.000
E32.8 Other diseases of thymus
0.462 0.538 0.000
E32.1 Abscess of thymus
0.462 0.538 0.000
E32.0 Persistent hyperplasia of thymus
0.462 0.538 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.462 0.538 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.462 0.538 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.462 0.538 0.000
E29.9 Testicular dysfunction, unspecified
0.461 0.539 0.000
E29.8 Other testicular dysfunction
0.461 0.539 0.000
E29.0 Testicular hyperfunction
0.461 0.539 0.000
E29.1 Testicular hypofunction
0.458 0.542 0.000
E31.9 Polyglandular dysfunction, unspecified
0.457 0.542 0.000
E31.8 Other polyglandular dysfunction
0.457 0.542 0.000
E31.1 Polyglandular hyperfunction
0.457 0.542 0.000
M10.08 Idiopathic gout (Other)
0.456 0.544 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.456 0.544 0.000
M10.03 Idiopathic gout (Forearm)
0.456 0.544 0.000
M10.02 Idiopathic gout (Upper arm)
0.456 0.544 0.000
M10.01 Idiopathic gout (Shoulder region)
0.456 0.544 0.000
E25.9 Adrenogenital disorder, unspecified
0.456 0.544 0.000
E25.8 Other adrenogenital disorders
0.456 0.544 0.000
M10.93 Gout, unspecified (Forearm)
0.455 0.545 0.000
K90 Intestinal malabsorption
0.451 0.549 0.000
E31.0 Autoimmune polyglandular failure
0.451 0.549 0.000
M10.04 Idiopathic gout (Hand)
0.450 0.550 0.000
M10.00 Idiopathic gout (Multiple sites)
0.450 0.550 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.447 0.553 0.000
E28.3 Primary ovarian failure
0.446 0.554 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.445 0.555 0.000
E27.9 Disorder of adrenal gland, unspecified
0.445 0.555 0.000
M10.09 Idiopathic gout (Site unspecified)
0.445 0.555 0.000
M11.1 Familial chondrocalcinosis
0.445 0.555 0.000
M11.0 Hydroxyapatite deposition disease
0.445 0.555 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.445 0.555 0.000
M13.84 Other specified arthritis (Hand)
0.445 0.555 0.000
M13.87 Other specified arthritis (Ankle and foot)
0.443 0.557 0.000
E13.9 Without complications
0.441 0.559 0.000
E04.9 Non-toxic goitre, unspecified
0.440 0.560 0.000
M11.8 Other specified crystal arthropathies
0.438 0.562 0.000
E04.8 Other specified non-toxic goitre
0.437 0.563 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.435 0.565 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.435 0.565 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.435 0.565 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.435 0.565 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.435 0.565 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.435 0.565 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.435 0.565 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.435 0.565 0.000
E21.4 Other specified disorders of parathyroid gland
0.431 0.569 0.000
M12.2 Villonodular synovitis (pigmented)
0.430 0.569 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.430 0.570 0.000
M35 Other systemic involvement of connective tissue
0.430 0.570 0.000
E21.2 Other hyperparathyroidism
0.429 0.571 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.427 0.573 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.426 0.573 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.424 0.576 0.000
M20-M25 Other joint disorders
0.424 0.576 0.000
M10.98 Gout, unspecified (Other)
0.422 0.578 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.422 0.578 0.000
M10.91 Gout, unspecified (Shoulder region)
0.422 0.578 0.000
E28.9 Ovarian dysfunction, unspecified
0.422 0.578 0.000
E28.8 Other ovarian dysfunction
0.422 0.578 0.000
E28.1 Androgen excess
0.422 0.578 0.000
E28.0 Oestrogen excess
0.422 0.578 0.000
M13.88 Other specified arthritis (Other)
0.416 0.583 0.000
M13.85 Other specified arthritis (Pelvic region and thigh)
0.416 0.583 0.000
M13.83 Other specified arthritis (Forearm)
0.416 0.583 0.000
M13.82 Other specified arthritis (Upper arm)
0.416 0.583 0.000
M13.81 Other specified arthritis (Shoulder region)
0.416 0.583 0.000
E21.3 Hyperparathyroidism, unspecified
0.411 0.589 0.000
M31 Other necrotising vasculopathies
0.411 0.589 0.000
M10.19 Lead-induced gout (Site unspecified)
0.408 0.592 0.000
M10.18 Lead-induced gout (Other)
0.408 0.592 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.408 0.592 0.000
M10.16 Lead-induced gout (Lower leg)
0.408 0.592 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.408 0.592 0.000
M10.14 Lead-induced gout (Hand)
0.408 0.592 0.000
M10.13 Lead-induced gout (Forearm)
0.408 0.592 0.000
M10.12 Lead-induced gout (Upper arm)
0.408 0.592 0.000
M10.11 Lead-induced gout (Shoulder region)
0.408 0.592 0.000
M10.10 Lead-induced gout (Multiple sites)
0.408 0.592 0.000
M10.29 Drug-induced gout (Site unspecified)
0.408 0.592 0.000
M10.28 Drug-induced gout (Other)
0.408 0.592 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.408 0.592 0.000
M10.26 Drug-induced gout (Lower leg)
0.408 0.592 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.408 0.592 0.000
M10.24 Drug-induced gout (Hand)
0.408 0.592 0.000
M10.23 Drug-induced gout (Forearm)
0.408 0.592 0.000
M10.22 Drug-induced gout (Upper arm)
0.408 0.592 0.000
M10.21 Drug-induced gout (Shoulder region)
0.408 0.592 0.000
M10.20 Drug-induced gout (Multiple sites)
0.408 0.592 0.000
M10.39 Gout due to impairment of renal function (Site unspecified)
0.408 0.592 0.000
M10.38 Gout due to impairment of renal function (Other)
0.408 0.592 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.408 0.592 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.408 0.592 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.408 0.592 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.408 0.592 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.408 0.592 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.408 0.592 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.408 0.592 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.408 0.592 0.000
M10.49 Other secondary gout (Site unspecified)
0.408 0.592 0.000
M10.48 Other secondary gout (Other)
0.408 0.592 0.000
M10.47 Other secondary gout (Ankle and foot)
0.408 0.592 0.000
M10.46 Other secondary gout (Lower leg)
0.408 0.592 0.000
M10.45 Other secondary gout (Pelvic region and thigh)
0.408 0.592 0.000
M10.44 Other secondary gout (Hand)
0.408 0.592 0.000
M10.43 Other secondary gout (Forearm)
0.408 0.592 0.000
M10.42 Other secondary gout (Upper arm)
0.408 0.592 0.000
M10.41 Other secondary gout (Shoulder region)
0.408 0.592 0.000
M10.40 Other secondary gout (Multiple sites)
0.408 0.592 0.000
M86-M90 Other osteopathies
0.404 0.596 0.000
M12.57 Traumatic arthropathy (Ankle and foot)
0.403 0.597 0.000
M07.6 Other enteropathic arthropathies
0.403 0.597 0.000
M07.5 Arthropathy in ulcerative colitis
0.403 0.597 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.403 0.597 0.000
M07.2 Psoriatic spondylitis
0.403 0.597 0.000
M07.1 Arthritis mutilans
0.403 0.597 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.403 0.597 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.402 0.598 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.399 0.601 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.399 0.601 0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.395 0.605 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.395 0.605 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.395 0.605 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.395 0.605 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.395 0.605 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.395 0.605 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.395 0.605 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.395 0.605 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.395 0.605 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.395 0.605 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.395 0.605 0.000
M08.28 Juvenile arthritis with systemic onset (Other)
0.395 0.605 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.395 0.605 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.395 0.605 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.395 0.605 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.395 0.605 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.395 0.605 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.395 0.605 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.395 0.605 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.395 0.605 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.395 0.605 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.395 0.605 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.395 0.605 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.395 0.605 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.395 0.605 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.395 0.605 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.395 0.605 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.395 0.605 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.395 0.605 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.395 0.605 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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