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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129867
log Bayes Factor = 289.989
Chromosome 6   position 32,404,220  (GRCh37) Explore rs3129867 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M20-M25 Other joint disorders
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.001 0.999
E14.9 Without complications
0.000 0.001 0.999
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.001 0.999
J30-J39 Other diseases of upper respiratory tract
0.000 0.002 0.998
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
M06.0 Seronegative rheumatoid arthritis
0.000 0.004 0.996
E10.5 With peripheral circulatory complications
0.000 0.004 0.996
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E10.2 With renal complications
0.000 0.005 0.995
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.008 0.992
D64.9 Anaemia, unspecified
0.000 0.009 0.991
D60-D64 Aplastic and other anaemias
0.000 0.009 0.991
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.009 0.991
D64 Other anaemias
0.000 0.009 0.991
M34 Systemic sclerosis
0.000 0.014 0.986
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.015 0.985
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.017 0.983
E11.3 With ophthalmic complications
0.000 0.019 0.981
E11.1 With ketoacidosis
0.000 0.020 0.980
E06 Thyroiditis
0.000 0.021 0.979
L43 Lichen planus
0.000 0.022 0.978
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.022 0.978
L43.9 Lichen planus, unspecified
0.000 0.022 0.978
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.024 0.976
L40-L45 Papulosquamous disorders
0.000 0.025 0.975
M45 Ankylosing spondylitis
0.000 0.026 0.974
M45-M49 Spondylopathies
0.000 0.027 0.973
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.028 0.972
M65-M68 Disorders of synovium and tendon
0.000 0.032 0.968
M06.4 Inflammatory polyarthropathy
0.000 0.032 0.968
J33.8 Other polyp of sinus
0.000 0.033 0.967
E11.5 With peripheral circulatory complications
0.000 0.033 0.967
M06.3 Rheumatoid nodule
0.000 0.034 0.966
H36 Retinal disorders in diseases classified elsewhere
0.000 0.035 0.965
E11.9 Without complications
0.000 0.035 0.965
E06.3 Autoimmune thyroiditis
0.000 0.037 0.963
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.038 0.962
J32 Chronic sinusitis
0.000 0.040 0.960
E10.0 With coma
0.000 0.040 0.960
G35-G37 Demyelinating diseases of the central nervous system
0.954 0.041 0.005
K90 Intestinal malabsorption
0.000 0.041 0.959
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.047 0.953
M65 Synovitis and tenosynovitis
0.000 0.048 0.952
E10.8 With unspecified complications
0.000 0.050 0.950
Chapter XI Diseases of the digestive system
0.000 0.053 0.947
G37 Other demyelinating diseases of central nervous system
0.945 0.054 0.002
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.054 0.946
K90-K93 Other diseases of the digestive system
0.000 0.055 0.945
G37.9 Demyelinating disease of central nervous system, unspecified
0.940 0.060 0.000
H30-H36 Disorders of choroid and retina
0.000 0.060 0.940
L43.8 Other lichen planus
0.000 0.063 0.937
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.064 0.936
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.066 0.934
K70-K77 Diseases of liver
0.000 0.068 0.932
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.070 0.930
Chapter VII Diseases of the eye and adnexa
0.000 0.071 0.929
M34.1 CR(E)ST syndrome
0.000 0.072 0.928
K75 Other inflammatory liver diseases
0.000 0.073 0.927
M34.9 Systemic sclerosis, unspecified
0.000 0.075 0.925
K75.4 Autoimmune hepatitis
0.000 0.075 0.925
E07 Other disorders of thyroid
0.000 0.080 0.920
J84 Other interstitial pulmonary diseases
0.000 0.080 0.920
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.082 0.918
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.086 0.914
D50-D53 Nutritional anaemias
0.000 0.086 0.914
M06.34 Rheumatoid nodule (Hand)
0.000 0.087 0.913
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.089 0.911
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.094 0.906
J47 Bronchiectasis
0.000 0.095 0.905
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.100 0.900
M35.1 Other overlap syndromes
0.000 0.101 0.899
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.105 0.895
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.107 0.893
J86 Pyothorax
0.000 0.111 0.889
D50 Iron deficiency anaemia
0.000 0.113 0.887
M30 Polyarteritis nodosa and related conditions
0.000 0.113 0.887
K82 Other diseases of gallbladder
0.000 0.113 0.887
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.117 0.883
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.120 0.880
E14.1 With ketoacidosis
0.000 0.122 0.878
K82.8 Other specified diseases of gallbladder
0.000 0.122 0.878
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.129 0.871
J32.4 Chronic pansinusitis
0.000 0.131 0.869
D50.9 Iron deficiency anaemia, unspecified
0.000 0.132 0.868
K73 Chronic hepatitis, not elsewhere classified
0.000 0.135 0.865
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.138 0.862
J20-J22 Other acute lower respiratory infections
0.000 0.139 0.861
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.140 0.860
J46 Status asthmaticus
0.000 0.143 0.857
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.143 0.857
E07.9 Disorder of thyroid, unspecified
0.000 0.146 0.854
E10.6 With other specified complications
0.000 0.148 0.852
E11.4 With neurological complications
0.000 0.150 0.850
M35.7 Hypermobility syndrome
0.000 0.159 0.841
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.162 0.838
M20 Acquired deformities of fingers and toes
0.000 0.164 0.836
M35.2 Behcet's disease
0.000 0.174 0.826
H34 Retinal vascular occlusions
0.000 0.178 0.821
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.181 0.819
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.183 0.817
J86.9 Pyothorax without fistula
0.000 0.187 0.813
J32.0 Chronic maxillary sinusitis
0.000 0.188 0.812
D50.8 Other iron deficiency anaemias
0.000 0.190 0.810
J32.8 Other chronic sinusitis
0.000 0.190 0.810
M65.1 Other infective (teno)synovitis
0.000 0.192 0.808
E14.8 With unspecified complications
0.000 0.196 0.804
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.198 0.802
J37 Chronic laryngitis and laryngotracheitis
0.000 0.199 0.801
D62 Acute posthaemorrhagic anaemia
0.000 0.200 0.800
L57.0 Actinic keratosis
0.000 0.200 0.800
E11.2 With renal complications
0.000 0.202 0.798
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.205 0.795
K81 Cholecystitis
0.000 0.206 0.794
E03.8 Other specified hypothyroidism
0.000 0.211 0.789
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.216 0.784
M14 Arthropathies in other diseases classified elsewhere
0.000 0.217 0.783
K81.9 Cholecystitis, unspecified
0.000 0.219 0.781
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.220 0.780
E11.6 With other specified complications
0.000 0.221 0.779
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.224 0.776
M30.0 Polyarteritis nodosa
0.000 0.226 0.774
K82.2 Perforation of gallbladder
0.000 0.230 0.770
K73.9 Chronic hepatitis, unspecified
0.000 0.234 0.766
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.234 0.766
E11.8 With unspecified complications
0.000 0.235 0.765
M31 Other necrotising vasculopathies
0.000 0.235 0.765
L10-L14 Bullous disorders
0.000 0.235 0.765
E14.2 Withrenal complications
0.000 0.236 0.764
K72 Hepatic failure, not elsewhere classified
0.000 0.236 0.764
J22 Unspecified acute lower respiratory infection
0.000 0.237 0.763
J85 Abscess of lung and mediastinum
0.000 0.237 0.763
J32.9 Chronic sinusitis, unspecified
0.000 0.237 0.763
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.238 0.762
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.239 0.761
M34.8 Other forms of systemic sclerosis
0.000 0.240 0.760
K82.3 Fistula of gallbladder
0.000 0.242 0.758
J86.0 Pyothorax with fistula
0.000 0.247 0.753
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.252 0.748
D53 Other nutritional anaemias
0.000 0.255 0.745
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.260 0.740
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.260 0.740
K90.9 Intestinal malabsorption, unspecified
0.000 0.262 0.738
E06.9 Thyroiditis, unspecified
0.000 0.264 0.736
M32 Systemic lupus erythematosus
0.000 0.267 0.733
E14.4 With neurological complications
0.000 0.269 0.731
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.269 0.731
M35.0 Sicca syndrome [Sjogren]
0.000 0.271 0.729
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.281 0.719
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.283 0.717
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.283 0.717
M35.5 Multifocal fibrosclerosis
0.000 0.283 0.717
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.286 0.714
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.286 0.714
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.286 0.714
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.286 0.714
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.286 0.714
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.286 0.714
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.286 0.714
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.289 0.711
H40-H42 Glaucoma
0.000 0.290 0.710
D64.4 Congenital dyserythropoietic anaemia
0.000 0.290 0.710
D64.3 Other sideroblastic anaemias
0.000 0.290 0.710
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.290 0.710
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.290 0.710
D64.0 Hereditary sideroblastic anaemia
0.000 0.290 0.710
E14.5 With peripheral circulatory complications
0.000 0.291 0.709
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.291 0.709
K85 Acute pancreatitis
0.000 0.291 0.709
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.293 0.707
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.293 0.707
M34.0 Progressive systemic sclerosis
0.000 0.293 0.707
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.293 0.706
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.294 0.706
K75.9 Inflammatory liver disease, unspecified
0.000 0.295 0.705
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.296 0.704
E06.5 Other chronic thyroiditis
0.000 0.298 0.702
E06.4 Drug-induced thyroiditis
0.000 0.298 0.702
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.298 0.702
E06.1 Subacute thyroiditis
0.000 0.298 0.702
E06.0 Acute thyroiditis
0.000 0.298 0.702
L43.3 Subacute (active) lichen planus
0.000 0.299 0.701
L43.2 Lichenoid drug reaction
0.000 0.299 0.701
L43.1 Bullous lichen planus
0.000 0.299 0.701
L43.0 Hypertrophic lichen planus
0.000 0.299 0.701
M49 Spondylopathies in diseases classified elsewhere
0.000 0.299 0.701
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.300 0.700
E05.8 Other thyrotoxicosis
0.000 0.301 0.699
L41 Parapsoriasis
0.000 0.301 0.699
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.301 0.699
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.302 0.698
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.302 0.698
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.302 0.698
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.302 0.698
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.302 0.698
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.302 0.698
J32.2 Chronic ethmoidal sinusitis
0.000 0.302 0.698
H34.2 Other retinal artery occlusions
0.000 0.304 0.696
M12 Other specific arthropathies
0.000 0.305 0.694
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.306 0.694
E07.8 Other specified disorders of thyroid
0.000 0.306 0.694
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.306 0.694
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.306 0.694
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.306 0.694
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.306 0.694
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.306 0.694
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.306 0.694
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.306 0.694
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.306 0.694
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.307 0.693
M06.38 Rheumatoid nodule (Other)
0.000 0.307 0.693
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.307 0.693
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.307 0.693
M06.33 Rheumatoid nodule (Forearm)
0.000 0.307 0.693
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.307 0.693
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.308 0.692
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.308 0.692
J41 Simple and mucopurulent chronic bronchitis
0.000 0.310 0.690
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.312 0.688
K90.3 Pancreatic steatorrhoea
0.000 0.313 0.687
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.313 0.687
K90.1 Tropical sprue
0.000 0.313 0.687
K82.9 Disease of gallbladder, unspecified
0.000 0.316 0.684
G37.8 Other specified demyelinating diseases of central nervous system
0.682 0.317 0.001
M65.2 Calcific tendinitis
0.000 0.317 0.683
M65.0 Abscess of tendon sheath
0.000 0.317 0.683
K72.0 Acute and subacute hepatic failure
0.000 0.318 0.682
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.319 0.681
J32.1 Chronic frontal sinusitis
0.000 0.320 0.680
G37.5 Concentric sclerosis [Balo]
0.677 0.321 0.001
G37.4 Subacute necrotising myelitis
0.677 0.321 0.001
G37.2 Central pontine myelinolysis
0.677 0.321 0.001
G37.1 Central demyelination of corpus callosum
0.677 0.321 0.001
G37.0 Diffuse sclerosis
0.677 0.321 0.001
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.322 0.678
J60-J70 Lung diseases due to external agents
0.000 0.322 0.677
K71 Toxic liver disease
0.000 0.323 0.677
M60-M63 Disorders of muscles
0.000 0.324 0.675
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.325 0.675
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.326 0.674
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.329 0.671
E16.1 Other hypoglycaemia
0.000 0.329 0.671
E40-E46 Malnutrition
0.000 0.329 0.671
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.329 0.671
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.329 0.671
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.329 0.671
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.329 0.671
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.329 0.671
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.329 0.671
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.329 0.671
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.329 0.671
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.329 0.670
M14.6 Neuropathic arthropathy
0.000 0.331 0.669
K77 Liver disorders in diseases classified elsewhere
0.000 0.332 0.668
J31.2 Chronic pharyngitis
0.000 0.333 0.667
K75.2 Nonspecific reactive hepatitis
0.000 0.335 0.664
K75.1 Phlebitis of portal vein
0.000 0.335 0.664
E13 Other specified diabetes mellitus
0.000 0.336 0.664
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.338 0.662
G36 Other acute disseminated demyelination
0.658 0.338 0.004
J85.2 Abscess of lung without pneumonia
0.000 0.340 0.660
E07.1 Dyshormogenetic goitre
0.000 0.340 0.660
E07.0 Hypersecretion of calcitonin
0.000 0.340 0.660
J37.0 Chronic laryngitis
0.000 0.340 0.660
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.341 0.659
L44 Other papulosquamous disorders
0.000 0.341 0.659
H30 Chorioretinal inflammation
0.000 0.343 0.657
M66 Spontaneous rupture of synovium and tendon
0.000 0.344 0.656
H34.8 Other retinal vascular occlusions
0.000 0.344 0.656
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.345 0.655
M24 Other specific joint derangements
0.000 0.345 0.655
J45.1 Nonallergic asthma
0.000 0.348 0.652
K85.1 Biliary acute pancreatitis
0.000 0.349 0.651
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.351 0.649
K74 Fibrosis and cirrhosis of liver
0.000 0.351 0.649
J42 Unspecified chronic bronchitis
0.000 0.353 0.647
L12 Pemphigoid
0.000 0.354 0.646
Chapter VIII Diseases of the ear and mastoid process
0.000 0.354 0.646
K50-K52 Noninfective enteritis and colitis
0.004 0.357 0.639
K75.8 Other specified inflammatory liver diseases
0.000 0.357 0.643
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.359 0.641
E20-E35 Disorders of other endocrine glands
0.000 0.361 0.639
J31.1 Chronic nasopharyngitis
0.000 0.362 0.638
J95-J99 Other diseases of the respiratory system
0.000 0.363 0.637
H35 Other retinal disorders
0.000 0.363 0.637
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.364 0.636
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.364 0.636
M30.2 Juvenile polyarteritis
0.000 0.364 0.636
J21 Acute bronchiolitis
0.000 0.365 0.635
D61 Other aplastic anaemias
0.000 0.367 0.633
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.369 0.631
L42 Pityriasis rosea
0.000 0.371 0.629
M80-M85 Disorders of bone density and structure
0.000 0.374 0.626
L55 Sunburn
0.000 0.376 0.624
D50.1 Sideropenic dysphagia
0.000 0.376 0.623
D53.9 Nutritional anaemia, unspecified
0.000 0.377 0.623
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.379 0.620
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.379 0.620
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.379 0.620
L80 Vitiligo
0.000 0.381 0.619
J84.0 Alveolar and parietoalveolar conditions
0.000 0.382 0.618
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.383 0.617
M31.6 Other giant cell arteritis
0.000 0.384 0.616
M67 Other disorders of synovium and tendon
0.000 0.385 0.615
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.385 0.614
J45.8 Mixed asthma
0.000 0.386 0.614
H60-H62 Diseases of external ear
0.000 0.386 0.614
K52 Other non-infective gastro-enteritis and colitis
0.001 0.390 0.609
H35.8 Other specified retinal disorders
0.000 0.391 0.609
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.391 0.609
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.392 0.607
K90.8 Other intestinal malabsorption
0.000 0.393 0.607
H34.1 Central retinal artery occlusion
0.000 0.395 0.605
M91-M94 Chondropathies
0.000 0.396 0.604
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.396 0.604
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.397 0.603
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.401 0.598
J32.3 Chronic sphenoidal sinusitis
0.000 0.403 0.597
J20 Acute bronchitis
0.000 0.404 0.596
K82.1 Hydrops of gallbladder
0.000 0.405 0.595
M80 Osteoporosis with pathological fracture
0.000 0.407 0.593
M00-M03 Infectious arthropathies
0.000 0.407 0.593
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.408 0.592
L20-L30 Dermatitis and eczema
0.000 0.409 0.591
D63.0 Anaemia in neoplastic disease
0.000 0.410 0.590
E50-E64 Other nutritional deficiencies
0.000 0.411 0.589
E11.0 With coma
0.000 0.411 0.589
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.588 0.411 0.001
H34.0 Transient retinal artery occlusion
0.000 0.411 0.589
L57.5 Actinic granuloma
0.000 0.414 0.586
L57.3 Poikiloderma of Civatte
0.000 0.414 0.586
L57.2 Cutis rhomboidalis nuchae
0.000 0.414 0.586
L57.1 Actinic reticuloid
0.000 0.414 0.586
E03.1 Congenital hypothyroidism without goitre
0.000 0.414 0.585
M15-M19 Arthrosis
0.000 0.415 0.585
J84.8 Other specified interstitial pulmonary diseases
0.000 0.415 0.585
H34.9 Retinal vascular occlusion, unspecified
0.000 0.416 0.584
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.416 0.584
H35.4 Peripheral retinal degeneration
0.000 0.416 0.584
K52.1 Toxic gastro-enteritis and colitis
0.000 0.416 0.584
M31.1 Thrombotic microangiopathy
0.000 0.420 0.580
M11 Other crystal arthropathies
0.000 0.421 0.579
M60 Myositis
0.000 0.421 0.579
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.421 0.579
M65.18 Other infective (teno)synovitis (Other)
0.000 0.421 0.579
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.421 0.579
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.421 0.579
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.421 0.579
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.421 0.579
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.421 0.579
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.421 0.579
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.421 0.579
M18 Arthrosis of first carpometacarpal joint
0.000 0.421 0.579
L28 Lichen simplex chronicus and prurigo
0.000 0.422 0.578
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.423 0.577
H10-H13 Disorders of conjunctiva
0.000 0.425 0.575
J37.1 Chronic laryngotracheitis
0.000 0.426 0.574
J43 Emphysema
0.000 0.427 0.573
L13 Other bullous disorders
0.000 0.429 0.571
M07 Psoriatic and enteropathic arthropathies
0.000 0.432 0.568
M20.0 Deformity of finger(s)
0.000 0.432 0.568
M24.1 Other articular cartilage disorders
0.000 0.433 0.567
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.434 0.566
H04 Disorders of lachrymal system
0.000 0.435 0.565
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.438 0.562
M14.4 Arthropathy in amyloidosis
0.000 0.438 0.562
M14.3 Lipoid dermatoarthritis
0.000 0.438 0.562
M14.2 Diabetic arthropathy
0.000 0.438 0.562
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.438 0.562
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.438 0.562
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.439 0.561
M35.8 Other specified systemic involvement of connective tissue
0.000 0.439 0.561
H61 Other disorders of external ear
0.000 0.440 0.560
D61.1 Drug-induced aplastic anaemia
0.000 0.440 0.560
D64.8 Other specified anaemias
0.000 0.441 0.559
L28.0 Lichen simplex chronicus
0.000 0.441 0.559
K74.3 Primary biliary cirrhosis
0.000 0.442 0.558
E23 Hypofunction and other disorders of pituitary gland
0.000 0.443 0.557
L12.1 Cicatricial pemphigoid
0.000 0.444 0.556
J45.0 Predominantly allergic asthma
0.000 0.445 0.554
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.446 0.554
H40 Glaucoma
0.000 0.446 0.554
K74.5 Biliary cirrhosis, unspecified
0.000 0.447 0.553
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.448 0.552
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.451 0.549
M31.8 Other specified necrotising vasculopathies
0.000 0.451 0.548
M31.7 Microscopic polyangiitis
0.000 0.451 0.548
M31.2 Lethal midline granuloma
0.000 0.451 0.548
L10 Pemphigus
0.000 0.452 0.548
L14 Bullous disorders in diseases classified elsewhere
0.000 0.452 0.548
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.452 0.547
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.453 0.547
D55-D59 Haemolytic anaemias
0.000 0.453 0.547
J85.3 Abscess of mediastinum
0.000 0.453 0.547
J85.0 Gangrene and necrosis of lung
0.000 0.453 0.547
M66.2 Spontaneous rupture of extensor tendons
0.000 0.455 0.545
H40.9 Glaucoma, unspecified
0.000 0.457 0.543
L58 Radiodermatitis
0.000 0.459 0.541
K82.0 Obstruction of gallbladder
0.000 0.459 0.541
H60 Otitis externa
0.000 0.460 0.540
H35.6 Retinal haemorrhage
0.000 0.461 0.539
L95.8 Other vasculitis limited to skin
0.000 0.464 0.536
M24.7 Protrusio acetabuli
0.000 0.465 0.535
D53.8 Other specified nutritional anaemias
0.000 0.466 0.534
D53.2 Scorbutic anaemia
0.000 0.466 0.534
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.466 0.534
D53.0 Protein deficiency anaemia
0.000 0.466 0.534
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.466 0.534
M82 Osteoporosis in diseases classified elsewhere
0.000 0.471 0.529
K75.0 Abscess of liver
0.000 0.471 0.529
E28 Ovarian dysfunction
0.000 0.471 0.529
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.474 0.526
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.474 0.526
E27 Other disorders of adrenal gland
0.000 0.475 0.525
K85.8 Other acute pancreatitis
0.000 0.475 0.525
L57.4 Cutis laxa senilis
0.000 0.476 0.524
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.477 0.522

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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