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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9268877
log Bayes Factor = 301.004
Chromosome 6   position 32,431,147  (GRCh37) Explore rs9268877 on Ensembl!
Variant rs9268877 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
J33 Nasal polyp
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Z93.2 Ileostomy status
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
C44.7 Skin of lower limb, including hip
1.000 0.000 0.000
J33.8 Other polyp of sinus
0.000 0.001 0.999
J30-J39 Other diseases of upper respiratory tract
0.000 0.002 0.998
K90 Intestinal malabsorption
0.000 0.002 0.998
E11.1 With ketoacidosis
0.000 0.003 0.997
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.003 0.997
M06 Other rheumatoid arthritis
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.004 0.996
K51.8 Other ulcerative colitis
0.996 0.004 0.000
# Top node
0.000 0.004 0.996
K51.4 Pseudopolyposis of colon
0.995 0.005 0.000
Chapter XI Diseases of the digestive system
0.000 0.005 0.995
K90-K93 Other diseases of the digestive system
0.000 0.005 0.995
M05 Seropositive rheumatoid arthritis
0.000 0.006 0.994
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.006 0.994
E10.5 With peripheral circulatory complications
0.000 0.006 0.994
J46 Status asthmaticus
0.000 0.008 0.992
M05-M14 Inflammatory polyarthropathies
0.000 0.008 0.992
K70-K77 Diseases of liver
0.000 0.009 0.991
J44 Other chronic obstructive pulmonary disease
0.000 0.012 0.988
K51.2 Ulcerative (chronic) proctitis
0.987 0.013 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.013 0.987
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.014 0.986
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.015 0.985
E10.8 With unspecified complications
0.000 0.015 0.985
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.017 0.983
K55-K64 Other diseases of intestines
0.000 0.017 0.983
C44.5 Skin of trunk
0.983 0.017 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.018 0.982
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.019 0.981
K60 Fissure and fistula of anal and rectal regions
0.000 0.020 0.980
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.021 0.979
K57 Diverticular disease of intestine
0.000 0.021 0.979
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.022 0.978
E10.2 With renal complications
0.000 0.022 0.978
E11.3 With ophthalmic complications
0.000 0.024 0.976
D64.9 Anaemia, unspecified
0.000 0.025 0.975
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.025 0.975
J43 Emphysema
0.000 0.028 0.972
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.029 0.971
K51.3 Ulcerative (chronic) rectosigmoiditis
0.970 0.030 0.000
D64 Other anaemias
0.000 0.031 0.969
J86 Pyothorax
0.000 0.033 0.967
D60-D64 Aplastic and other anaemias
0.000 0.033 0.967
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.043 0.957
J43.9 Emphysema, unspecified
0.000 0.046 0.954
E11.5 With peripheral circulatory complications
0.000 0.047 0.953
C44.1 Skin of eyelid, including canthus
0.953 0.047 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.049 0.951
E05.9 Thyrotoxicosis, unspecified
0.000 0.056 0.944
C44.2 Skin of ear and external auricular canal
0.940 0.060 0.000
Chapter VIII Diseases of the ear and mastoid process
0.000 0.064 0.936
K60.0 Acute anal fissure
0.000 0.064 0.936
K60.2 Anal fissure, unspecified
0.000 0.066 0.934
H60-H62 Diseases of external ear
0.000 0.069 0.931
J95-J99 Other diseases of the respiratory system
0.000 0.072 0.928
H61 Other disorders of external ear
0.000 0.074 0.926
K75 Other inflammatory liver diseases
0.000 0.074 0.926
K74.3 Primary biliary cirrhosis
0.000 0.075 0.925
J86.9 Pyothorax without fistula
0.000 0.079 0.921
H61.0 Perichondritis of external ear
0.000 0.079 0.921
D50-D53 Nutritional anaemias
0.000 0.083 0.917
G35-G37 Demyelinating diseases of the central nervous system
0.910 0.084 0.005
E10.0 With coma
0.000 0.087 0.913
E10.6 With other specified complications
0.000 0.088 0.912
E13 Other specified diabetes mellitus
0.000 0.088 0.912
J86.0 Pyothorax with fistula
0.000 0.091 0.909
K75.4 Autoimmune hepatitis
0.000 0.093 0.907
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.094 0.906
K76 Other diseases of liver
0.000 0.096 0.904
J32 Chronic sinusitis
0.000 0.097 0.903
K76.8 Other specified diseases of liver
0.000 0.097 0.903
E50-E64 Other nutritional deficiencies
0.000 0.098 0.902
M06.3 Rheumatoid nodule
0.000 0.104 0.896
E40-E46 Malnutrition
0.000 0.106 0.894
G37 Other demyelinating diseases of central nervous system
0.890 0.109 0.001
D50 Iron deficiency anaemia
0.000 0.114 0.886
E14.6 With other specified complications
0.000 0.118 0.882
K73 Chronic hepatitis, not elsewhere classified
0.000 0.118 0.882
D50.9 Iron deficiency anaemia, unspecified
0.000 0.118 0.882
C44.4 Skin of scalp and neck
0.876 0.124 0.000
E14.1 With ketoacidosis
0.000 0.128 0.872
K90.9 Intestinal malabsorption, unspecified
0.000 0.129 0.871
G37.9 Demyelinating disease of central nervous system, unspecified
0.870 0.130 0.000
K51.5 Mucosal proctocolitis
0.870 0.130 0.000
E14.8 With unspecified complications
0.000 0.132 0.868
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.136 0.864
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.137 0.863
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.143 0.857
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.145 0.855
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.146 0.854
E16.1 Other hypoglycaemia
0.000 0.149 0.851
K60.1 Chronic anal fissure
0.000 0.150 0.850
L90.0 Lichen sclerosus et atrophicus
0.000 0.150 0.850
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.153 0.847
L90 Atrophic disorders of skin
0.000 0.157 0.843
E13.9 Without complications
0.000 0.158 0.842
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.158 0.842
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.165 0.835
J37 Chronic laryngitis and laryngotracheitis
0.000 0.172 0.828
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.174 0.826
E61 Deficiency of other nutrient elements
0.000 0.176 0.824
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.177 0.823
K60.5 Anorectal fistula
0.000 0.179 0.821
E46 Unspecified protein-energy malnutrition
0.000 0.181 0.819
E53 Deficiency of other B group vitamins
0.000 0.183 0.817
E11.2 With renal complications
0.000 0.186 0.814
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.187 0.813
H61.3 Acquired stenosis of external ear canal
0.000 0.194 0.806
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.195 0.805
J32.2 Chronic ethmoidal sinusitis
0.000 0.197 0.803
K74.5 Biliary cirrhosis, unspecified
0.000 0.198 0.802
L92.0 Granuloma annulare
0.000 0.204 0.796
L40-L45 Papulosquamous disorders
0.000 0.205 0.795
K58 Irritable bowel syndrome
0.000 0.207 0.793
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.000 0.211 0.789
J98 Other respiratory disorders
0.000 0.212 0.788
C44.9 Malignant neoplasm of skin, unspecified
0.787 0.213 0.000
L80 Vitiligo
0.000 0.215 0.785
E61.1 Iron deficiency
0.000 0.215 0.785
M06.4 Inflammatory polyarthropathy
0.000 0.217 0.783
M05.8 Other seropositive rheumatoid arthritis
0.000 0.217 0.783
E14.5 With peripheral circulatory complications
0.000 0.218 0.782
K55 Vascular disorders of intestine
0.000 0.221 0.779
K72 Hepatic failure, not elsewhere classified
0.000 0.223 0.777
C44.6 Skin of upper limb, including shoulder
0.777 0.223 0.000
M12 Other specific arthropathies
0.000 0.224 0.776
E53.8 Deficiency of other specified B group vitamins
0.000 0.227 0.773
E11.6 With other specified complications
0.000 0.227 0.773
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.228 0.772
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.229 0.771
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.232 0.768
L40.9 Psoriasis, unspecified
0.000 0.232 0.768
L40 Psoriasis
0.000 0.233 0.767
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.000 0.234 0.766
K60.4 Rectal fistula
0.000 0.234 0.766
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.234 0.766
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.234 0.766
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.238 0.762
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.245 0.755
N48.6 Balanitis xerotica obliterans
0.000 0.247 0.753
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.248 0.752
J98.4 Other disorders of lung
0.000 0.250 0.750
M06.34 Rheumatoid nodule (Hand)
0.000 0.254 0.746
H61.1 Non-infective disorders of pinna
0.000 0.254 0.746
E03.1 Congenital hypothyroidism without goitre
0.000 0.257 0.743
N48 Other disorders of penis
0.000 0.258 0.742
K74.0 Hepatic fibrosis
0.000 0.260 0.740
J43.2 Centrilobular emphysema
0.000 0.262 0.738
E14.2 Withrenal complications
0.000 0.262 0.738
L10-L14 Bullous disorders
0.000 0.265 0.735
J33.1 Polypoid sinus degeneration
0.000 0.266 0.734
M06.8 Other specified rheumatoid arthritis
0.000 0.273 0.727
J32.4 Chronic pansinusitis
0.000 0.275 0.725
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.277 0.723
K55.2 Angiodysplasia of colon
0.000 0.278 0.722
N48.0 Leukoplakia of penis
0.000 0.281 0.719
J32.9 Chronic sinusitis, unspecified
0.000 0.282 0.718
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.284 0.715
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.284 0.715
K90.1 Tropical sprue
0.000 0.284 0.715
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.285 0.715
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.285 0.715
M06.2 Rheumatoid bursitis
0.000 0.285 0.715
H60 Otitis externa
0.000 0.285 0.715
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.286 0.714
C44.0 Skin of lip
0.713 0.287 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.287 0.713
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.287 0.713
M05.1 Rheumatoid lung disease
0.000 0.287 0.713
M05.0 Felty's syndrome
0.000 0.287 0.713
J32.8 Other chronic sinusitis
0.000 0.287 0.713
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.288 0.711
M08 Juvenile arthritis
0.000 0.288 0.711
K77 Liver disorders in diseases classified elsewhere
0.000 0.289 0.710
J41 Simple and mucopurulent chronic bronchitis
0.000 0.290 0.710
H61.8 Other specified disorders of external ear
0.000 0.291 0.709
D51 Vitamin B12 deficiency anaemia
0.000 0.291 0.709
J98.6 Disorders of diaphragm
0.000 0.292 0.708
E05.5 Thyroid crisis or storm
0.000 0.292 0.707
E05.4 Thyrotoxicosis factitia
0.000 0.292 0.707
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.292 0.707
J95.0 Tracheostomy malfunction
0.000 0.293 0.707
J37.0 Chronic laryngitis
0.000 0.294 0.706
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.295 0.705
J85 Abscess of lung and mediastinum
0.000 0.303 0.697
J43.1 Panlobular emphysema
0.000 0.303 0.697
J43.0 MacLeod's syndrome
0.000 0.303 0.697
D53 Other nutritional anaemias
0.000 0.304 0.696
E06 Thyroiditis
0.000 0.304 0.696
D64.4 Congenital dyserythropoietic anaemia
0.000 0.305 0.695
D64.3 Other sideroblastic anaemias
0.000 0.305 0.695
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.305 0.695
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.305 0.695
D64.0 Hereditary sideroblastic anaemia
0.000 0.305 0.695
J45.1 Nonallergic asthma
0.000 0.306 0.694
L50-L54 Urticaria and erythema
0.000 0.306 0.694
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.307 0.693
K76.1 Chronic passive congestion of liver
0.000 0.307 0.693
N40-N51 Diseases of male genital organs
0.000 0.307 0.693
J32.3 Chronic sphenoidal sinusitis
0.000 0.307 0.692
M14 Arthropathies in other diseases classified elsewhere
0.000 0.308 0.692
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.308 0.692
J45.0 Predominantly allergic asthma
0.000 0.309 0.691
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.689 0.310 0.001
E03.8 Other specified hypothyroidism
0.000 0.311 0.688
E14.4 With neurological complications
0.000 0.313 0.687
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.313 0.687
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.317 0.683
K74.4 Secondary biliary cirrhosis
0.000 0.318 0.682
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.318 0.682
K75.8 Other specified inflammatory liver diseases
0.000 0.318 0.682
M05.2 Rheumatoid vasculitis
0.000 0.319 0.681
E11.8 With unspecified complications
0.000 0.320 0.680
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.322 0.678
K73.9 Chronic hepatitis, unspecified
0.000 0.322 0.678
E13.3 With ophthalmic complications
0.000 0.322 0.678
L13 Other bullous disorders
0.000 0.323 0.677
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.323 0.677
H80-H83 Diseases of inner ear
0.000 0.326 0.674
Chapter XIV Diseases of the genitourinary system
0.000 0.333 0.667
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.333 0.667
E20-E35 Disorders of other endocrine glands
0.000 0.334 0.666
N48.1 Balanoposthitis
0.000 0.334 0.666
J96 Respiratory failure, not elsewhere classified
0.000 0.334 0.666
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.335 0.665
G36 Other acute disseminated demyelination
0.661 0.336 0.004
K75.2 Nonspecific reactive hepatitis
0.000 0.336 0.664
K75.1 Phlebitis of portal vein
0.000 0.336 0.664
M06.1 Adult-onset Still's disease
0.000 0.337 0.663
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.337 0.663
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.339 0.661
E07 Other disorders of thyroid
0.000 0.340 0.660
J90-J94 Other diseases of pleura
0.000 0.341 0.659
E56 Other vitamin deficiencies
0.000 0.341 0.659
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.342 0.658
G37.8 Other specified demyelinating diseases of central nervous system
0.657 0.342 0.001
E11.0 With coma
0.000 0.343 0.657
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.344 0.656
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.344 0.656
E13.8 With unspecified complications
0.000 0.346 0.654
E13.7 With multiple complications
0.000 0.346 0.654
E13.6 With other specified complications
0.000 0.346 0.654
E13.5 With peripheral circulatory complications
0.000 0.346 0.654
E13.4 With neurological complications
0.000 0.346 0.654
E13.2 With renal complications
0.000 0.346 0.654
E13.1 With ketoacidosis
0.000 0.346 0.654
E13.0 With coma
0.000 0.346 0.654
H36 Retinal disorders in diseases classified elsewhere
0.000 0.346 0.654
L89 Decubitus ulcer
0.000 0.348 0.652
D50.1 Sideropenic dysphagia
0.000 0.349 0.651
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.350 0.650
N00-N08 Glomerular diseases
0.000 0.350 0.650
K51.1 Ulcerative (chronic) ileocolitis
0.649 0.351 0.000
J45.8 Mixed asthma
0.000 0.352 0.648
K76.5 Hepatic veno-occlusive disease
0.000 0.352 0.648
K76.4 Peliosis hepatis
0.000 0.352 0.648
K76.3 Infarction of liver
0.000 0.352 0.648
K76.2 Central haemorrhagic necrosis of liver
0.000 0.352 0.648
J32.1 Chronic frontal sinusitis
0.000 0.352 0.648
K55.1 Chronic vascular disorders of intestine
0.000 0.352 0.648
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.353 0.647
E63 Other nutritional deficiencies
0.000 0.353 0.647
E50 Vitamin A deficiency
0.000 0.353 0.647
E60 Dietary zinc deficiency
0.000 0.353 0.647
E59 Dietary selenium deficiency
0.000 0.353 0.647
E54 Ascorbic acid deficiency
0.000 0.353 0.647
E52 Niacin deficiency [pellagra]
0.000 0.353 0.647
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.354 0.646
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.000 0.355 0.645
K71 Toxic liver disease
0.000 0.357 0.643
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.357 0.643
M06.38 Rheumatoid nodule (Other)
0.000 0.357 0.643
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.357 0.643
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.357 0.643
M06.33 Rheumatoid nodule (Forearm)
0.000 0.357 0.643
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.357 0.643
E51 Thiamine deficiency
0.000 0.357 0.642
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.359 0.641
E45 Retarded development following protein-energy malnutrition
0.000 0.359 0.641
E43 Unspecified severe protein-energy malnutrition
0.000 0.359 0.641
E42 Marasmic kwashiorkor
0.000 0.359 0.641
E41 Nutritional marasmus
0.000 0.359 0.641
E40 Kwashiorkor
0.000 0.359 0.641
J99.0 Rheumatoid lung disease
0.000 0.359 0.641
G37.5 Concentric sclerosis [Balo]
0.638 0.361 0.001
G37.4 Subacute necrotising myelitis
0.638 0.361 0.001
G37.2 Central pontine myelinolysis
0.638 0.361 0.001
G37.1 Central demyelination of corpus callosum
0.638 0.361 0.001
G37.0 Diffuse sclerosis
0.638 0.361 0.001
M12.3 Palindromic rheumatism
0.000 0.361 0.639
L13.0 Dermatitis herpetiformis
0.000 0.365 0.635
N49.2 Inflammatory disorders of scrotum
0.000 0.368 0.632
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.368 0.632
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.368 0.632
L43 Lichen planus
0.000 0.368 0.632
K72.0 Acute and subacute hepatic failure
0.000 0.369 0.631
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.369 0.631
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.371 0.629
J98.2 Interstitial emphysema
0.000 0.371 0.629
L50 Urticaria
0.000 0.372 0.628
M10 Gout
0.000 0.373 0.627
D55-D59 Haemolytic anaemias
0.000 0.375 0.625
J93 Pneumothorax
0.000 0.376 0.624
K86 Other diseases of pancreas
0.000 0.377 0.623
K86.1 Other chronic pancreatitis
0.000 0.380 0.620
J39 Other diseases of upper respiratory tract
0.000 0.380 0.620
J43.8 Other emphysema
0.000 0.381 0.618
J93.9 Pneumothorax, unspecified
0.000 0.384 0.616
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.387 0.613
K60.3 Anal fistula
0.000 0.388 0.612
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.389 0.611
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.391 0.609
L87 Transepidermal elimination disorders
0.000 0.392 0.608
L86 Keratoderma in diseases classified elsewhere
0.000 0.392 0.608
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.394 0.606
L90.9 Atrophic disorder of skin, unspecified
0.000 0.396 0.604
L90.6 Striae atrophicae
0.000 0.396 0.604
L90.4 Acrodermatitis chronica atrophicans
0.000 0.396 0.604
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.396 0.604
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.396 0.604
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.396 0.604
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.397 0.603
L89.2 Stage III decubitus ulcer
0.000 0.397 0.603
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.400 0.600
Q80-Q89 Other congenital malformations
0.000 0.401 0.599
K51.0 Ulcerative (chronic) enterocolitis
0.595 0.405 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.406 0.594
J37.1 Chronic laryngotracheitis
0.000 0.406 0.594
D64.8 Other specified anaemias
0.000 0.407 0.593
E61.9 Deficiency of nutrient element, unspecified
0.000 0.409 0.591
E61.8 Deficiency of other specified nutrient elements
0.000 0.409 0.591
E61.7 Deficiency of multiple nutrient elements
0.000 0.409 0.591
E61.6 Vanadium deficiency
0.000 0.409 0.591
E61.5 Molybdenum deficiency
0.000 0.409 0.591
E61.4 Chromium deficiency
0.000 0.409 0.591
E61.3 Manganese deficiency
0.000 0.409 0.591
E61.0 Copper deficiency
0.000 0.409 0.591
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.411 0.589
L91 Hypertrophic disorders of skin
0.000 0.412 0.588
Q38-Q45 Other congenital malformations of the digestive system
0.000 0.412 0.588
E53.1 Pyridoxine deficiency
0.000 0.414 0.586
E53.0 Riboflavin deficiency
0.000 0.414 0.586
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.417 0.583
N48.9 Disorder of penis, unspecified
0.000 0.423 0.577
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.424 0.576
J31.2 Chronic pharyngitis
0.000 0.425 0.575
E05.8 Other thyrotoxicosis
0.000 0.425 0.575
K50-K52 Noninfective enteritis and colitis
0.155 0.427 0.418
J85.2 Abscess of lung without pneumonia
0.000 0.429 0.571
L52 Erythema nodosum
0.000 0.429 0.571
C43-C44 Melanoma and other malignant neoplasms of skin
0.551 0.430 0.019
L44 Other papulosquamous disorders
0.000 0.430 0.570
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.430 0.570
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.000 0.431 0.569
K72.1 Chronic hepatic failure
0.000 0.432 0.568
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.432 0.568
K74.6 Other and unspecified cirrhosis of liver
0.000 0.433 0.567
J98.3 Compensatory emphysema
0.000 0.435 0.565
K90.8 Other intestinal malabsorption
0.000 0.435 0.564
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.437 0.563
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.438 0.562
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.438 0.562
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.438 0.562
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.438 0.562
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.438 0.562
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.438 0.562
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.438 0.562
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.438 0.562
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.439 0.561
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.439 0.561
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.439 0.561
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.439 0.561
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.439 0.561
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.439 0.561
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.439 0.561
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.439 0.561
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.439 0.561
K57.0 Diverticular disease of small intestine with perforation and abscess
0.000 0.439 0.561
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.439 0.561
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.441 0.559
L50.0 Allergic urticaria
0.000 0.441 0.559
E21.0 Primary hyperparathyroidism
0.000 0.441 0.559
J98.8 Other specified respiratory disorders
0.000 0.442 0.558
E24 Cushing's syndrome
0.000 0.443 0.557
M12.5 Traumatic arthropathy
0.000 0.443 0.556
M12.4 Intermittent hydrarthrosis
0.000 0.443 0.556
M12.1 Kaschin-Beck disease
0.000 0.443 0.556
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.443 0.556
E06.3 Autoimmune thyroiditis
0.000 0.444 0.556
H60.5 Acute otitis externa, non-infective
0.000 0.444 0.556
L40.3 Pustulosis palmaris et plantaris
0.000 0.444 0.555
J42 Unspecified chronic bronchitis
0.000 0.448 0.552
J95.5 Postprocedural subglottic stenosis
0.000 0.449 0.551
J95.4 Mendelson's syndrome
0.000 0.449 0.551
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.449 0.551
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.449 0.551
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.449 0.551
L40.2 Acrodermatitis continua
0.000 0.450 0.550
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.450 0.550
D62 Acute posthaemorrhagic anaemia
0.000 0.457 0.543
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.000 0.460 0.540
M14.6 Neuropathic arthropathy
0.000 0.460 0.540
E58 Dietary calcium deficiency
0.000 0.460 0.540
H60.9 Otitis externa, unspecified
0.000 0.461 0.539
Q85 Phakomatoses, not elsewhere classified
0.000 0.461 0.539
L40.1 Generalised pustular psoriasis
0.000 0.461 0.539
H81 Disorders of vestibular function
0.000 0.461 0.539
H60.3 Other infective otitis externa
0.000 0.462 0.538
D53.9 Nutritional anaemia, unspecified
0.000 0.462 0.537
N25-N29 Other disorders of kidney and ureter
0.000 0.463 0.537
E29 Testicular dysfunction
0.000 0.463 0.537
K72.9 Hepatic failure, unspecified
0.000 0.464 0.536
N42 Other disorders of prostate
0.000 0.465 0.535
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.466 0.534
H61.9 Disorder of external ear, unspecified
0.000 0.467 0.533
L94 Other localised connective tissue disorders
0.000 0.467 0.533
M11 Other crystal arthropathies
0.000 0.467 0.533
E20 Hypoparathyroidism
0.000 0.468 0.532
H60.2 Malignant otitis externa
0.000 0.470 0.530
K86.3 Pseudocyst of pancreas
0.000 0.470 0.530
L43.9 Lichen planus, unspecified
0.000 0.470 0.530
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.471 0.529
L14 Bullous disorders in diseases classified elsewhere
0.000 0.473 0.527
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.000 0.473 0.527
L41 Parapsoriasis
0.000 0.475 0.525
H60.4 Cholesteatoma of external ear
0.000 0.475 0.525
N48.3 Priapism
0.000 0.475 0.525
Q43 Other congenital malformations of intestine
0.000 0.478 0.522
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.478 0.522
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.478 0.521
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.478 0.521
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.478 0.521
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.478 0.521
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.478 0.521
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.478 0.521
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.478 0.521
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.478 0.521
N42.2 Atrophy of prostate
0.000 0.479 0.521
M12.2 Villonodular synovitis (pigmented)
0.000 0.480 0.520
H80 Otosclerosis
0.000 0.481 0.519
L11 Other acantholytic disorders
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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