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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3021302
log Bayes Factor = 364.737
Chromosome 6   position 32,623,150  (GRCh37) Explore rs3021302 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
D50 Iron deficiency anaemia
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
D50.9 Iron deficiency anaemia, unspecified
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
E14.3 With ophthalmic complications
1.000 0.000 0.000
G56.0 Carpal tunnel syndrome
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
G56 Mononeuropathies of upper limb
1.000 0.000 0.000
K75.4 Autoimmune hepatitis
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E27.1 Primary adrenocortical insufficiency
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
E27 Other disorders of adrenal gland
0.999 0.001 0.000
E10.4 With neurological complications
0.999 0.001 0.000
K90-K93 Other diseases of the digestive system
0.999 0.001 0.000
H00.1 Chalazion
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
N04 Nephrotic syndrome
0.999 0.001 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.999 0.001 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
D69.6 Thrombocytopenia, unspecified
0.998 0.002 0.000
I63 Cerebral infarction
0.998 0.002 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.998 0.002 0.000
E11.3 With ophthalmic complications
0.998 0.002 0.000
N05 Unspecified nephritic syndrome
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
E14.9 Without complications
0.997 0.003 0.000
K90.9 Intestinal malabsorption, unspecified
0.997 0.003 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.035 0.004 0.961
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.996 0.004 0.000
E89.0 Postprocedural hypothyroidism
0.996 0.004 0.000
N04.9 Unspecified
0.995 0.005 0.000
E10.2 With renal complications
0.995 0.005 0.000
M06 Other rheumatoid arthritis
0.003 0.006 0.992
N08 Glomerular disorders in diseases classified elsewhere
0.994 0.006 0.000
D51 Vitamin B12 deficiency anaemia
0.992 0.008 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.992 0.008 0.000
C85.1 B-cell lymphoma, unspecified
0.991 0.009 0.000
C91 Lymphoid leukaemia
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.989 0.011 0.000
C81 Hodgkin's disease
0.989 0.011 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.988 0.012 0.000
D50.8 Other iron deficiency anaemias
0.988 0.012 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.985 0.015 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.984 0.016 0.000
M05 Seropositive rheumatoid arthritis
0.016 0.016 0.968
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.983 0.017 0.000
L10-L14 Bullous disorders
0.982 0.018 0.000
H43-H45 Disorders of vitreous body and globe
0.981 0.019 0.000
N05.2 Diffuse membranous glomerulonephritis
0.981 0.019 0.000
Chapter XIV Diseases of the genitourinary system
0.981 0.019 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.002 0.020 0.978
G59 Mononeuropathy in diseases classified elsewhere
0.979 0.021 0.000
G35 Multiple sclerosis
0.978 0.022 0.000
K74 Fibrosis and cirrhosis of liver
0.978 0.022 0.000
D68 Other coagulation defects
0.978 0.022 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.022 0.978
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.978 0.022 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.977 0.023 0.000
H43 Disorders of vitreous body
0.974 0.026 0.000
N17-N19 Renal failure
0.972 0.028 0.000
I74 Arterial embolism and thrombosis
0.971 0.029 0.000
N18 Chronic renal failure
0.970 0.030 0.000
H34 Retinal vascular occlusions
0.969 0.031 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.968 0.032 0.000
G51 Facial nerve disorders
0.967 0.033 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.967 0.033 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.966 0.034 0.000
G59.0 Diabetic mononeuropathy
0.964 0.036 0.000
L13 Other bullous disorders
0.964 0.036 0.000
Chapter II Neoplasms
0.962 0.038 0.000
I77 Other disorders of arteries and arterioles
0.961 0.039 0.000
C91.1 Chronic lymphocytic leukaemia
0.961 0.039 0.000
C83.3 Large cell (diffuse)
0.960 0.040 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.960 0.040 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.958 0.042 0.000
M15-M19 Arthrosis
0.957 0.043 0.000
B07 Viral warts
0.956 0.044 0.000
N18.4 Chronic kidney disease, stage 4
0.954 0.046 0.000
M23 Internal derangement of knee
0.954 0.046 0.000
K73 Chronic hepatitis, not elsewhere classified
0.952 0.048 0.000
E06 Thyroiditis
0.952 0.048 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.951 0.049 0.000
L13.0 Dermatitis herpetiformis
0.951 0.049 0.000
M18 Arthrosis of first carpometacarpal joint
0.948 0.052 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.943 0.053 0.004
I64 Stroke, not specified as haemorrhage or infarction
0.946 0.054 0.000
E10.5 With peripheral circulatory complications
0.944 0.056 0.000
K50-K52 Noninfective enteritis and colitis
0.233 0.057 0.710
E11.1 With ketoacidosis
0.943 0.057 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.057 0.942
H43.1 Vitreous haemorrhage
0.942 0.058 0.000
E21.3 Hyperparathyroidism, unspecified
0.941 0.059 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.941 0.059 0.000
I73 Other peripheral vascular diseases
0.941 0.059 0.000
M24 Other specific joint derangements
0.940 0.060 0.000
H34.8 Other retinal vascular occlusions
0.940 0.060 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.939 0.061 0.000
M86-M90 Other osteopathies
0.938 0.062 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.936 0.062 0.002
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.938 0.062 0.000
C81.1 Nodular sclerosis
0.935 0.065 0.000
C81.9 Hodgkin's disease, unspecified
0.934 0.066 0.000
K75.8 Other specified inflammatory liver diseases
0.933 0.067 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.067 0.933
H06.2 Dysthyroid exophthalmos
0.931 0.068 0.000
N18.3 Chronic kidney disease, stage 3
0.931 0.069 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.070 0.930
L92 Granulomatous disorders of skin and subcutaneous tissue
0.929 0.071 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.927 0.073 0.000
M34 Systemic sclerosis
0.926 0.074 0.000
A63.0 Anogenital (venereal) warts
0.926 0.074 0.000
G51.0 Bell's palsy
0.924 0.076 0.000
E10.0 With coma
0.922 0.078 0.000
E07 Other disorders of thyroid
0.922 0.078 0.000
K74.6 Other and unspecified cirrhosis of liver
0.921 0.079 0.000
M86 Osteomyelitis
0.921 0.079 0.000
K35-K38 Diseases of appendix
0.917 0.083 0.000
D61 Other aplastic anaemias
0.917 0.083 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.917 0.083 0.000
E06.3 Autoimmune thyroiditis
0.915 0.085 0.000
I62 Other nontraumatic intracranial haemorrhage
0.913 0.087 0.000
L93 Lupus erythematosus
0.913 0.087 0.000
K72 Hepatic failure, not elsewhere classified
0.911 0.089 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.911 0.089 0.000
M23.8 Other internal derangements of knee
0.908 0.092 0.000
N05.9 Unspecified
0.906 0.094 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.906 0.094 0.000
N05.1 Focal and segmental glomerular lesions
0.903 0.097 0.000
C91.9 Lymphoid leukaemia, unspecified
0.902 0.098 0.000
E11.5 With peripheral circulatory complications
0.901 0.099 0.000
M23.5 Chronic instability of knee
0.899 0.101 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.101 0.899
L94 Other localised connective tissue disorders
0.899 0.101 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.898 0.102 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.897 0.103 0.000
M80-M85 Disorders of bone density and structure
0.897 0.103 0.000
H43.8 Other disorders of vitreous body
0.896 0.104 0.000
N40 Hyperplasia of prostate
0.000 0.104 0.896
K51 Ulcerative colitis
0.001 0.105 0.894
L40-L45 Papulosquamous disorders
0.824 0.106 0.069
D68.8 Other specified coagulation defects
0.893 0.107 0.000
M35.7 Hypermobility syndrome
0.891 0.109 0.000
D80-D89 Certain disorders involving the immune mechanism
0.891 0.109 0.000
D68.0 Von Willebrand's disease
0.890 0.110 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.889 0.111 0.000
M06.3 Rheumatoid nodule
0.001 0.111 0.888
L83 Acanthosis nigricans
0.885 0.115 0.000
B00 Herpesviral [herpes simplex] infections
0.883 0.117 0.000
M60-M63 Disorders of muscles
0.882 0.118 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.882 0.118 0.000
D69.4 Other primary thrombocytopenia
0.882 0.118 0.000
B25-B34 Other viral diseases
0.881 0.119 0.000
M86.9 Osteomyelitis, unspecified
0.881 0.119 0.000
M15 Polyarthrosis
0.880 0.120 0.000
H25-H28 Disorders of lens
0.880 0.120 0.000
K74.3 Primary biliary cirrhosis
0.880 0.120 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.877 0.123 0.000
L92.0 Granuloma annulare
0.877 0.123 0.000
D68.6 Other Thrombophilia
0.876 0.124 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.875 0.125 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.874 0.126 0.000
C04 Malignant neoplasm of floor of mouth
0.873 0.127 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.873 0.127 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.872 0.128 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.128 0.872
M32 Systemic lupus erythematosus
0.871 0.129 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.871 0.129 0.000
H46 Optic neuritis
0.871 0.129 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.871 0.129 0.000
M21 Other acquired deformities of limbs
0.868 0.132 0.000
M24.1 Other articular cartilage disorders
0.867 0.133 0.000
D55-D59 Haemolytic anaemias
0.866 0.134 0.000
L40.9 Psoriasis, unspecified
0.000 0.135 0.865
M07 Psoriatic and enteropathic arthropathies
0.017 0.136 0.846
N04.1 Focal and segmental glomerular lesions
0.861 0.139 0.000
I77.1 Stricture of artery
0.861 0.139 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.139 0.861
I10-I15 Hypertensive diseases
0.861 0.139 0.000
M33 Dermatopolymyositis
0.858 0.142 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.857 0.143 0.000
R63.4 Abnormal weight loss
0.856 0.144 0.000
I63.8 Other cerebral infarction
0.856 0.144 0.000
N04.2 Diffuse membranous glomerulonephritis
0.856 0.144 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.856 0.144 0.000
M81 Osteoporosis without pathological fracture
0.855 0.145 0.000
E14.5 With peripheral circulatory complications
0.855 0.145 0.000
E86 Volume depletion
0.851 0.149 0.000
L50-L54 Urticaria and erythema
0.851 0.149 0.000
I73.0 Raynaud's syndrome
0.849 0.151 0.000
H26 Other cataract
0.849 0.151 0.000
H00 Hordeolum and chalazion
0.139 0.152 0.709
D61.9 Aplastic anaemia, unspecified
0.847 0.153 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.846 0.154 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.845 0.155 0.000
C15-C26 Malignant neoplasms of digestive organs
0.845 0.155 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.845 0.155 0.000
E50-E64 Other nutritional deficiencies
0.843 0.157 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.843 0.157 0.000
E10.7 With multiple complications
0.842 0.158 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.841 0.159 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.839 0.161 0.000
H43.9 Disorder of vitreous body, unspecified
0.839 0.161 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.838 0.162 0.000
I12 Hypertensive renal disease
0.838 0.162 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.837 0.163 0.000
I73.9 Peripheral vascular disease, unspecified
0.837 0.163 0.000
M81.9 Osteoporosis, unspecified
0.836 0.163 0.000
H26.9 Cataract, unspecified
0.835 0.165 0.000
G11 Hereditary ataxia
0.834 0.166 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.834 0.166 0.000
I77.6 Arteritis, unspecified
0.833 0.167 0.000
M21.0 Valgus deformity, not elsewhere classified
0.832 0.168 0.000
G51.9 Disorder of facial nerve, unspecified
0.832 0.168 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.832 0.168 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.831 0.169 0.000
C07 Malignant neoplasm of parotid gland
0.830 0.170 0.000
E14.1 With ketoacidosis
0.829 0.171 0.000
E88 Other metabolic disorders
0.829 0.171 0.000
E10.8 With unspecified complications
0.828 0.172 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.828 0.172 0.000
H33 Retinal detachments and breaks
0.828 0.172 0.000
D73 Diseases of spleen
0.826 0.174 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.826 0.174 0.000
E22 Hyperfunction of pituitary gland
0.826 0.174 0.000
D69.8 Other specified haemorrhagic conditions
0.826 0.174 0.000
C20 Malignant neoplasm of rectum
0.825 0.175 0.000
K38 Other diseases of appendix
0.824 0.176 0.000
E14.4 With neurological complications
0.824 0.176 0.000
K72.0 Acute and subacute hepatic failure
0.823 0.177 0.000
E28 Ovarian dysfunction
0.823 0.177 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.822 0.178 0.000
L93.0 Discoid lupus erythematosus
0.821 0.179 0.000
D64.8 Other specified anaemias
0.819 0.181 0.000
C88 Malignant immunoproliferative diseases
0.819 0.181 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.818 0.182 0.000
N18.0 End-stage renal disease
0.818 0.182 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.818 0.182 0.000
K35 Acute appendicitis
0.816 0.184 0.000
E14.8 With unspecified complications
0.816 0.184 0.000
L43 Lichen planus
0.791 0.184 0.026
G58 Other mononeuropathies
0.815 0.185 0.000
E31 Polyglandular dysfunction
0.815 0.185 0.000
M06.34 Rheumatoid nodule (Hand)
0.001 0.187 0.813
E07.9 Disorder of thyroid, unspecified
0.813 0.187 0.000
E11.0 With coma
0.812 0.188 0.000
E10.6 With other specified complications
0.812 0.188 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.811 0.188 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.189 0.811
B35-B49 Mycoses
0.811 0.189 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.807 0.193 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.806 0.194 0.000
I74.5 Embolism and thrombosis of iliac artery
0.806 0.194 0.000
D69.2 Other nonthrombocytopenic purpura
0.803 0.197 0.000
K51.4 Pseudopolyposis of colon
0.000 0.197 0.803
G56.4 Causalgia
0.802 0.198 0.000
D70 Agranulocytosis
0.802 0.198 0.000
B00.9 Herpesviral infection, unspecified
0.802 0.198 0.000
E14.2 Withrenal complications
0.801 0.199 0.000
C83.0 Small cell (diffuse)
0.801 0.199 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.799 0.201 0.000
B15-B19 Viral hepatitis
0.793 0.207 0.000
N18.1 Chronic kidney disease, stage 1
0.792 0.208 0.000
G54 Nerve root and plexus disorders
0.792 0.208 0.000
C91.0 Acute lymphoblastic leukaemia
0.791 0.209 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.790 0.210 0.000
I74.8 Embolism and thrombosis of other arteries
0.790 0.210 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.790 0.210 0.000
M60 Myositis
0.789 0.211 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.212 0.788
M23.4 Loose body in knee
0.788 0.212 0.000
L94.0 Localised scleroderma [morphea]
0.787 0.213 0.000
E07.8 Other specified disorders of thyroid
0.787 0.213 0.000
K74.5 Biliary cirrhosis, unspecified
0.786 0.214 0.000
K73.9 Chronic hepatitis, unspecified
0.785 0.215 0.000
E89.4 Postprocedural ovarian failure
0.784 0.216 0.000
C83.1 Small cleaved cell (diffuse)
0.783 0.217 0.000
C04.9 Floor of mouth, unspecified
0.783 0.217 0.000
D52 Folate deficiency anaemia
0.781 0.219 0.000
M06.0 Seronegative rheumatoid arthritis
0.001 0.219 0.780
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.781 0.219 0.000
E13 Other specified diabetes mellitus
0.780 0.219 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.779 0.221 0.000
E11.2 With renal complications
0.779 0.221 0.000
N03 Chronic nephritic syndrome
0.779 0.221 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.779 0.221 0.000
I60 Subarachnoid haemorrhage
0.778 0.222 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.778 0.222 0.000
E73 Lactose intolerance
0.778 0.222 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.778 0.222 0.000
I12.9 Hypertensive renal disease without renal failure
0.778 0.222 0.000
K90.8 Other intestinal malabsorption
0.777 0.223 0.000
B25 Cytomegaloviral disease
0.777 0.223 0.000
C02.9 Tongue, unspecified
0.776 0.224 0.000
G11.9 Hereditary ataxia, unspecified
0.775 0.225 0.000
H30 Chorioretinal inflammation
0.774 0.226 0.000
C92 Myeloid leukaemia
0.774 0.226 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.774 0.226 0.000
I12.0 Hypertensive renal disease with renal failure
0.774 0.226 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.773 0.227 0.000
K60.2 Anal fissure, unspecified
0.772 0.228 0.000
E74 Other disorders of carbohydrate metabolism
0.772 0.228 0.000
D72 Other disorders of white blood cells
0.771 0.229 0.000
M34.0 Progressive systemic sclerosis
0.771 0.229 0.000
Q43 Other congenital malformations of intestine
0.770 0.230 0.000
L95.8 Other vasculitis limited to skin
0.770 0.230 0.000
D73.5 Infarction of spleen
0.769 0.231 0.000
M07.3 Other psoriatic arthropathies
0.005 0.231 0.764
M35.1 Other overlap syndromes
0.768 0.231 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.767 0.233 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.767 0.233 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.766 0.234 0.000
M34.1 CR(E)ST syndrome
0.766 0.234 0.000
L43.9 Lichen planus, unspecified
0.763 0.234 0.002
E11.6 With other specified complications
0.765 0.235 0.000
I65.2 Occlusion and stenosis of carotid artery
0.764 0.236 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.764 0.236 0.000
K35.9 Acute appendicitis, unspecified
0.763 0.237 0.000
E16.1 Other hypoglycaemia
0.763 0.237 0.000
B37 Candidiasis
0.763 0.237 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.762 0.238 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.761 0.239 0.000
C83.7 Burkitt's tumour
0.761 0.239 0.000
E40-E46 Malnutrition
0.761 0.239 0.000
G30-G32 Other degenerative diseases of the nervous system
0.758 0.242 0.000
M70-M79 Other soft tissue disorders
0.757 0.243 0.000
C23 Malignant neoplasm of gallbladder
0.756 0.244 0.000
G70-G73 Diseases of myoneural junction and muscle
0.756 0.244 0.000
L11 Other acantholytic disorders
0.755 0.245 0.000
C84.5 Other and unspecified T-cell lymphomas
0.755 0.245 0.000
K71 Toxic liver disease
0.755 0.245 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.754 0.246 0.000
H26.1 Traumatic cataract
0.754 0.246 0.000
A20-A28 Certain zoonotic bacterial diseases
0.754 0.246 0.000
H33.3 Retinal breaks without detachment
0.753 0.247 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.752 0.248 0.000
D68.2 Hereditary deficiency of other clotting factors
0.751 0.249 0.000
L12 Pemphigoid
0.750 0.250 0.000
L80 Vitiligo
0.750 0.250 0.000
H05 Disorders of orbit
0.748 0.250 0.002
M86.1 Other acute osteomyelitis
0.749 0.251 0.000
H35 Other retinal disorders
0.749 0.251 0.000
G51.8 Other disorders of facial nerve
0.749 0.251 0.000
M86.8 Other osteomyelitis
0.748 0.252 0.000
M24.5 Contracture of joint
0.748 0.252 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.748 0.252 0.000
C04.0 Anterior floor of mouth
0.748 0.252 0.000
G52 Disorders of other cranial nerves
0.747 0.253 0.000
B34 Viral infection of unspecified site
0.746 0.254 0.000
D80 Immunodeficiency with predominantly antibody defects
0.745 0.255 0.000
K60 Fissure and fistula of anal and rectal regions
0.744 0.256 0.000
C81.0 Lymphocytic predominance
0.744 0.256 0.000
K51.5 Mucosal proctocolitis
0.001 0.256 0.743
E21.0 Primary hyperparathyroidism
0.744 0.256 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.743 0.257 0.000
C81.2 Mixed cellularity
0.742 0.258 0.000
M33.2 Polymyositis
0.741 0.259 0.000
N05.8 Other
0.741 0.259 0.000
L40 Psoriasis
0.049 0.259 0.692
L93.2 Other local lupus erythematosus
0.741 0.259 0.000
M86.6 Other chronic osteomyelitis
0.740 0.260 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.740 0.260 0.000
H34.1 Central retinal artery occlusion
0.740 0.260 0.000
N17 Acute renal failure
0.739 0.261 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.738 0.262 0.000
G56.8 Other mononeuropathies of upper limb
0.737 0.263 0.000
E11.8 With unspecified complications
0.737 0.263 0.000
M34.9 Systemic sclerosis, unspecified
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.736 0.264 0.000
H34.2 Other retinal artery occlusions
0.735 0.265 0.000
B37.8 Candidiasis of other sites
0.735 0.265 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.734 0.266 0.000
G12 Spinal muscular atrophy and related syndromes
0.732 0.268 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.731 0.269 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.730 0.270 0.000
M20.1 Hallux valgus (acquired)
0.000 0.270 0.730
C10 Malignant neoplasm of oropharynx
0.729 0.271 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.729 0.271 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.729 0.271 0.000
Q60-Q64 Congenital malformations of the urinary system
0.728 0.272 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.726 0.274 0.000
M34.8 Other forms of systemic sclerosis
0.726 0.274 0.000
G58.9 Mononeuropathy, unspecified
0.726 0.274 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.726 0.274 0.000
I63.9 Cerebral infarction, unspecified
0.725 0.275 0.000
I70 Atherosclerosis
0.725 0.275 0.000
C15 Malignant neoplasm of oesophagus
0.724 0.276 0.000
K72.9 Hepatic failure, unspecified
0.724 0.276 0.000
G56.1 Other lesions of median nerve
0.723 0.277 0.000
E27.2 Addisonian crisis
0.720 0.279 0.000
Q80-Q89 Other congenital malformations
0.720 0.280 0.000
H33.1 Retinoschisis and retinal cysts
0.720 0.280 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.719 0.281 0.000
K38.8 Other specified diseases of appendix
0.718 0.282 0.000
M79.8 Other specified soft tissue disorders
0.718 0.282 0.000
D61.0 Constitutional aplastic anaemia
0.718 0.282 0.000
K50 Crohn's disease [regional enteritis]
0.008 0.283 0.709
D50.1 Sideropenic dysphagia
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.6 With other specified complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D67 Hereditary factor IX deficiency
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
N00 Acute nephritic syndrome
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
D69.1 Qualitative platelet defects
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E27.5 Adrenomedullary hyperfunction
0.717 0.283 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.717 0.283 0.000
E27.0 Other adrenocortical overactivity
0.717 0.283 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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