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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs910049
log Bayes Factor = 214.799
Chromosome 6   position 32,315,727  (GRCh37) Explore rs910049 on Ensembl!
Variant rs910049 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
M07 Psoriatic and enteropathic arthropathies
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
M35 Other systemic involvement of connective tissue
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
E14.3 With ophthalmic complications
0.000 0.003 0.997
M20-M25 Other joint disorders
0.000 0.004 0.996
# Top node
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.006 0.994
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
E11.1 With ketoacidosis
0.000 0.008 0.992
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.008 0.992
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.009 0.991
E10.5 With peripheral circulatory complications
0.000 0.010 0.990
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.010 0.990
L43 Lichen planus
0.000 0.014 0.986
H40-H42 Glaucoma
0.000 0.019 0.981
E10.2 With renal complications
0.000 0.022 0.978
E06 Thyroiditis
0.000 0.022 0.978
J33.0 Polyp of nasal cavity
0.000 0.026 0.974
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.027 0.973
J33 Nasal polyp
0.000 0.027 0.973
H40 Glaucoma
0.000 0.029 0.971
H40.9 Glaucoma, unspecified
0.000 0.030 0.970
J33.9 Nasal polyp, unspecified
0.000 0.031 0.969
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.033 0.967
L43.9 Lichen planus, unspecified
0.000 0.034 0.966
E06.3 Autoimmune thyroiditis
0.000 0.036 0.964
M06.0 Seronegative rheumatoid arthritis
0.000 0.037 0.963
M34 Systemic sclerosis
0.000 0.037 0.963
I10 Essential (primary) hypertension
0.000 0.038 0.962
I10-I15 Hypertensive diseases
0.000 0.039 0.961
E10.8 With unspecified complications
0.000 0.044 0.956
J33.8 Other polyp of sinus
0.000 0.045 0.955
H34 Retinal vascular occlusions
0.000 0.046 0.954
Chapter IX Diseases of the circulatory system
0.000 0.049 0.951
M06.3 Rheumatoid nodule
0.000 0.050 0.950
D64.9 Anaemia, unspecified
0.000 0.051 0.949
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.055 0.945
D64 Other anaemias
0.000 0.056 0.944
E10.0 With coma
0.000 0.056 0.944
D60-D64 Aplastic and other anaemias
0.000 0.056 0.944
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.058 0.942
M45-M49 Spondylopathies
0.000 0.076 0.924
M45 Ankylosing spondylitis
0.000 0.076 0.924
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.076 0.924
E78.2 Mixed hyperlipidaemia
0.000 0.077 0.923
H35 Other retinal disorders
0.000 0.077 0.923
I22 Subsequent myocardial infarction
0.000 0.078 0.922
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.080 0.920
I20-I25 Ischaemic heart diseases
0.000 0.082 0.918
M65-M68 Disorders of synovium and tendon
0.000 0.086 0.914
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.091 0.909
I12 Hypertensive renal disease
0.000 0.092 0.908
M06.4 Inflammatory polyarthropathy
0.000 0.095 0.905
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.096 0.904
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.097 0.903
E88 Other metabolic disorders
0.000 0.098 0.902
I12.9 Hypertensive renal disease without renal failure
0.000 0.115 0.885
M34.1 CR(E)ST syndrome
0.000 0.116 0.884
M65 Synovitis and tenosynovitis
0.000 0.117 0.883
H35.8 Other specified retinal disorders
0.000 0.120 0.880
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.121 0.879
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.122 0.878
H35.4 Peripheral retinal degeneration
0.000 0.123 0.877
M34.9 Systemic sclerosis, unspecified
0.000 0.126 0.874
E07 Other disorders of thyroid
0.000 0.128 0.872
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.130 0.870
M35.7 Hypermobility syndrome
0.000 0.133 0.867
E78.1 Pure hyperglyceridaemia
0.000 0.135 0.865
M35.1 Other overlap syndromes
0.000 0.137 0.863
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.138 0.862
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.139 0.861
E11.5 With peripheral circulatory complications
0.000 0.139 0.861
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.140 0.860
L40.8 Other psoriasis
0.000 0.140 0.860
M06.34 Rheumatoid nodule (Hand)
0.000 0.143 0.857
G37.8 Other specified demyelinating diseases of central nervous system
0.856 0.144 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.150 0.850
H34.2 Other retinal artery occlusions
0.000 0.153 0.847
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.154 0.846
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.154 0.846
E11.2 With renal complications
0.000 0.156 0.844
L43.8 Other lichen planus
0.000 0.157 0.843
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.165 0.835
H34.8 Other retinal vascular occlusions
0.000 0.168 0.832
E89.0 Postprocedural hypothyroidism
0.000 0.172 0.828
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.174 0.826
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.177 0.823
E10.6 With other specified complications
0.000 0.178 0.822
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.182 0.818
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.183 0.817
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.190 0.810
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.193 0.807
D50-D53 Nutritional anaemias
0.000 0.195 0.805
E03.8 Other specified hypothyroidism
0.000 0.198 0.802
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.204 0.796
E14.4 With neurological complications
0.000 0.204 0.796
M30 Polyarteritis nodosa and related conditions
0.000 0.205 0.795
H35.6 Retinal haemorrhage
0.000 0.208 0.792
H40.4 Glaucoma secondary to eye inflammation
0.000 0.216 0.784
E74 Other disorders of carbohydrate metabolism
0.000 0.218 0.782
L57.0 Actinic keratosis
0.000 0.223 0.777
D50 Iron deficiency anaemia
0.000 0.229 0.771
M31 Other necrotising vasculopathies
0.000 0.229 0.771
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.229 0.771
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.230 0.770
M35.2 Behcet's disease
0.000 0.231 0.769
E07.9 Disorder of thyroid, unspecified
0.000 0.234 0.766
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.235 0.765
E11.8 With unspecified complications
0.000 0.242 0.758
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.243 0.757
E14.5 With peripheral circulatory complications
0.000 0.243 0.756
D50.8 Other iron deficiency anaemias
0.000 0.247 0.753
E83 Disorders of mineral metabolism
0.359 0.250 0.391
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.251 0.749
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.253 0.747
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.254 0.746
I15 Secondary hypertension
0.000 0.254 0.745
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.743 0.257 0.000
H35.7 Separation of retinal layers
0.000 0.258 0.742
H40.5 Glaucoma secondary to other eye disorders
0.000 0.260 0.740
L40.3 Pustulosis palmaris et plantaris
0.000 0.265 0.735
E14.2 Withrenal complications
0.000 0.265 0.735
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.266 0.734
H34.1 Central retinal artery occlusion
0.000 0.267 0.733
H34.9 Retinal vascular occlusion, unspecified
0.000 0.268 0.732
D62 Acute posthaemorrhagic anaemia
0.000 0.271 0.729
G36 Other acute disseminated demyelination
0.726 0.273 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.275 0.725
H30 Chorioretinal inflammation
0.000 0.276 0.724
E88.2 Lipomatosis, not elsewhere classified
0.000 0.276 0.724
I22.8 Subsequent myocardial infarction of other sites
0.000 0.277 0.723
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.278 0.722
E88.8 Other specified metabolic disorders
0.000 0.278 0.721
H40.1 Primary open-angle glaucoma
0.000 0.279 0.721
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.279 0.721
L40.0 Psoriasis vulgaris
0.000 0.280 0.720
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.281 0.719
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
L44 Other papulosquamous disorders
0.000 0.283 0.716
L41 Parapsoriasis
0.000 0.283 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.283 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.283 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.283 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.283 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.283 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.716
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.716
M07.2 Psoriatic spondylitis
0.000 0.284 0.716
M07.1 Arthritis mutilans
0.000 0.284 0.716
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.284 0.716
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.284 0.716
M35.5 Multifocal fibrosclerosis
0.000 0.284 0.716
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.000 0.284 0.716
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.284 0.716
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.284 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.284 0.716
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.284 0.716
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.284 0.716
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.286 0.714
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.286 0.714
M34.8 Other forms of systemic sclerosis
0.000 0.286 0.713
G37.5 Concentric sclerosis [Balo]
0.713 0.287 0.000
G37.4 Subacute necrotising myelitis
0.713 0.287 0.000
G37.2 Central pontine myelinolysis
0.713 0.287 0.000
G37.1 Central demyelination of corpus callosum
0.713 0.287 0.000
G37.0 Diffuse sclerosis
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.000 0.287 0.713
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.288 0.712
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.292 0.708
L43.3 Subacute (active) lichen planus
0.000 0.293 0.707
L43.2 Lichenoid drug reaction
0.000 0.293 0.707
L43.1 Bullous lichen planus
0.000 0.293 0.707
L43.0 Hypertrophic lichen planus
0.000 0.293 0.707
M91-M94 Chondropathies
0.000 0.296 0.704
I11 Hypertensive heart disease
0.000 0.296 0.704
H42 Glaucoma in diseases classified elsewhere
0.000 0.297 0.703
E70 Disorders of aromatic amino-acid metabolism
0.000 0.298 0.702
E06.5 Other chronic thyroiditis
0.000 0.299 0.701
E06.4 Drug-induced thyroiditis
0.000 0.299 0.701
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.299 0.701
E06.1 Subacute thyroiditis
0.000 0.299 0.701
E06.0 Acute thyroiditis
0.000 0.299 0.701
Chapter VIII Diseases of the ear and mastoid process
0.000 0.301 0.699
J33.1 Polypoid sinus degeneration
0.000 0.302 0.698
H40.6 Glaucoma secondary to drugs
0.000 0.304 0.696
H40.3 Glaucoma secondary to eye trauma
0.000 0.304 0.696
E40-E46 Malnutrition
0.000 0.304 0.696
M65.1 Other infective (teno)synovitis
0.000 0.305 0.695
E79 Disorders of purine and pyrimidine metabolism
0.000 0.305 0.695
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.305 0.695
E78.4 Other hyperlipidaemia
0.000 0.306 0.694
I00-I02 Acute rheumatic fever
0.000 0.307 0.693
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.309 0.690
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.309 0.690
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.309 0.690
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.309 0.690
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.309 0.690
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.309 0.690
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.310 0.690
M34.0 Progressive systemic sclerosis
0.000 0.310 0.690
E11.4 With neurological complications
0.000 0.310 0.690
I13 Hypertensive heart and renal disease
0.000 0.311 0.689
E16.1 Other hypoglycaemia
0.000 0.311 0.689
H35.2 Other proliferative retinopathy
0.000 0.311 0.689
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.312 0.688
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.312 0.688
E11.6 With other specified complications
0.000 0.313 0.687
H34.0 Transient retinal artery occlusion
0.000 0.316 0.684
M12 Other specific arthropathies
0.000 0.317 0.683
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.318 0.682
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.319 0.681
M06.38 Rheumatoid nodule (Other)
0.000 0.319 0.681
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.319 0.681
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.319 0.681
M06.33 Rheumatoid nodule (Forearm)
0.000 0.319 0.681
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.319 0.681
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.319 0.681
D64.4 Congenital dyserythropoietic anaemia
0.000 0.323 0.677
D64.3 Other sideroblastic anaemias
0.000 0.323 0.677
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.323 0.677
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.323 0.677
D64.0 Hereditary sideroblastic anaemia
0.000 0.323 0.677
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.323 0.677
M07.6 Other enteropathic arthropathies
0.000 0.329 0.670
D50.9 Iron deficiency anaemia, unspecified
0.000 0.330 0.670
M86-M90 Other osteopathies
0.000 0.331 0.669
E84 Cystic fibrosis
0.000 0.331 0.669
H60-H62 Diseases of external ear
0.000 0.334 0.666
E06.9 Thyroiditis, unspecified
0.000 0.336 0.664
M15-M19 Arthrosis
0.000 0.336 0.664
H40.0 Glaucoma suspect
0.000 0.337 0.663
M31.6 Other giant cell arteritis
0.000 0.337 0.663
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.338 0.662
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.338 0.662
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.338 0.662
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.338 0.662
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.338 0.662
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.338 0.662
E89.4 Postprocedural ovarian failure
0.000 0.338 0.662
H35.1 Retinopathy of prematurity
0.000 0.338 0.662
E13 Other specified diabetes mellitus
0.000 0.338 0.662
M66 Spontaneous rupture of synovium and tendon
0.000 0.339 0.661
E72 Other disorders of amino-acid metabolism
0.000 0.339 0.661
H33 Retinal detachments and breaks
0.000 0.342 0.658
E07.8 Other specified disorders of thyroid
0.000 0.343 0.657
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.343 0.657
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.345 0.655
M32 Systemic lupus erythematosus
0.000 0.346 0.654
E88.3 Tumour lysis syndrome
0.000 0.346 0.654
M49 Spondylopathies in diseases classified elsewhere
0.000 0.349 0.651
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.349 0.651
D55-D59 Haemolytic anaemias
0.000 0.350 0.649
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.351 0.649
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.351 0.649
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.351 0.649
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.351 0.649
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.351 0.649
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.351 0.649
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.351 0.649
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.351 0.649
E88.9 Metabolic disorder, unspecified
0.000 0.353 0.647
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.353 0.647
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.354 0.646
M11 Other crystal arthropathies
0.000 0.361 0.639
L10-L14 Bullous disorders
0.000 0.364 0.635
M65.2 Calcific tendinitis
0.000 0.367 0.633
M65.0 Abscess of tendon sheath
0.000 0.367 0.633
M80-M85 Disorders of bone density and structure
0.000 0.369 0.631
M33 Dermatopolymyositis
0.000 0.370 0.630
M18 Arthrosis of first carpometacarpal joint
0.000 0.370 0.630
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.370 0.630
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.370 0.630
E89.5 Postprocedural testicular hypofunction
0.000 0.370 0.630
E89.1 Postprocedural hypoinsulinaemia
0.000 0.370 0.630
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.372 0.628
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.373 0.627
L42 Pityriasis rosea
0.000 0.374 0.626
E07.1 Dyshormogenetic goitre
0.000 0.375 0.625
E07.0 Hypersecretion of calcitonin
0.000 0.375 0.625
E65-E68 Obesity and other hyperalimentation
0.000 0.375 0.625
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.379 0.621
L55 Sunburn
0.000 0.382 0.618
M60-M63 Disorders of muscles
0.000 0.383 0.617
E05.8 Other thyrotoxicosis
0.000 0.384 0.616
M86 Osteomyelitis
0.000 0.384 0.615
E89.3 Postprocedural hypopituitarism
0.000 0.386 0.614
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.388 0.612
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.390 0.610
M30.0 Polyarteritis nodosa
0.000 0.391 0.609
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.391 0.609
H61 Other disorders of external ear
0.000 0.391 0.609
H43-H45 Disorders of vitreous body and globe
0.000 0.394 0.606
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.395 0.604
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.396 0.604
E73 Lactose intolerance
0.000 0.399 0.601
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.400 0.600
D53 Other nutritional anaemias
0.000 0.402 0.597
L20-L30 Dermatitis and eczema
0.000 0.403 0.597
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.405 0.594
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.410 0.590
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.410 0.590
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.410 0.590
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.410 0.590
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.410 0.590
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.410 0.590
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.410 0.590
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.410 0.590
I15.9 Seconday hypertension, unspecified
0.000 0.411 0.589
H60 Otitis externa
0.000 0.412 0.588
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.413 0.587
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.415 0.585
M86.9 Osteomyelitis, unspecified
0.000 0.416 0.584
E89.2 Postprocedural hypoparathyroidism
0.000 0.416 0.583
H33.3 Retinal breaks without detachment
0.000 0.420 0.580
D61 Other aplastic anaemias
0.000 0.421 0.579
L57.5 Actinic granuloma
0.000 0.421 0.579
L57.3 Poikiloderma of Civatte
0.000 0.421 0.579
L57.2 Cutis rhomboidalis nuchae
0.000 0.421 0.579
L57.1 Actinic reticuloid
0.000 0.421 0.579
M31.3 Wegener's granulomatosis
0.000 0.422 0.577
L28 Lichen simplex chronicus and prurigo
0.000 0.425 0.575
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.430 0.570
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.430 0.570
M30.2 Juvenile polyarteritis
0.000 0.430 0.570
M10 Gout
0.000 0.431 0.569
H46 Optic neuritis
0.000 0.431 0.569
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.432 0.568
I23 Certain current complications following acute myocardial infarction
0.000 0.433 0.567
M14.6 Neuropathic arthropathy
0.000 0.433 0.567
M31.9 Necrotising vasculopathy, unspecified
0.000 0.434 0.566
I15.1 Hypertension secondary to other renal disorders
0.000 0.435 0.565
L58 Radiodermatitis
0.000 0.435 0.565
E03.1 Congenital hypothyroidism without goitre
0.000 0.435 0.565
M82 Osteoporosis in diseases classified elsewhere
0.000 0.435 0.565
M31.1 Thrombotic microangiopathy
0.000 0.437 0.563
M80 Osteoporosis with pathological fracture
0.000 0.439 0.561
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.439 0.561
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.439 0.561
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.439 0.561
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.439 0.561
E74.2 Disorders of galactose metabolism
0.000 0.439 0.561
E74.1 Disorders of fructose metabolism
0.000 0.439 0.561
E74.0 Glycogen storage disease
0.000 0.439 0.561
M00-M03 Infectious arthropathies
0.000 0.439 0.561
E78.8 Other disorders of lipoprotein metabolism
0.000 0.443 0.557
E20-E35 Disorders of other endocrine glands
0.000 0.446 0.554
E11.0 With coma
0.000 0.446 0.554
D50.1 Sideropenic dysphagia
0.000 0.447 0.553
M31.8 Other specified necrotising vasculopathies
0.000 0.447 0.553
M31.7 Microscopic polyangiitis
0.000 0.447 0.553
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.447 0.553
M31.2 Lethal midline granuloma
0.000 0.447 0.553
H35.5 Hereditary retinal dystrophy
0.000 0.447 0.553
M15 Polyarthrosis
0.000 0.448 0.552
M35.0 Sicca syndrome [Sjogren]
0.000 0.451 0.549
L28.0 Lichen simplex chronicus
0.000 0.451 0.549
H61.0 Perichondritis of external ear
0.000 0.456 0.544
M94 Other disorders of cartilage
0.000 0.456 0.544
M66.2 Spontaneous rupture of extensor tendons
0.000 0.456 0.543
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.457 0.542
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.462 0.538
E83.8 Other disorders of mineral metabolism
0.257 0.462 0.281
E83.2 Disorders of zinc metabolism
0.257 0.462 0.281
E83.0 Disorders of copper metabolism
0.257 0.462 0.281
M92 Other juvenile osteochondrosis
0.000 0.464 0.536
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.464 0.536
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.000 0.465 0.535
I15.8 Other secondary hypertension
0.000 0.465 0.534
I15.2 Hypertension secondary to endocrine disorders
0.000 0.465 0.534
H33.4 Traction detachment of retina
0.000 0.466 0.534
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.466 0.534
G36.0 Neuromyelitis optica [Devic]
0.533 0.466 0.000
H61.8 Other specified disorders of external ear
0.000 0.467 0.533
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.470 0.530
H30.9 Chorioretinal inflammation, unspecified
0.000 0.472 0.527
E83.9 Disorder of mineral metabolism, unspecified
0.278 0.473 0.249
I21 Acute myocardial infarction
0.000 0.477 0.523
H60.3 Other infective otitis externa
0.000 0.478 0.521
G36.9 Acute disseminated demyelination, unspecified
0.521 0.479 0.000
G36.8 Other specified acute disseminated demyelination
0.521 0.479 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.521 0.479 0.000
H30.8 Other chorioretinal inflammations
0.000 0.481 0.519
H30.2 Posterior cyclitis
0.000 0.481 0.519
H30.1 Disseminated chorioretinal inflammation
0.000 0.481 0.519
H30.0 Focal chorioretinal inflammation
0.000 0.481 0.519
M82.1 Osteoporosis in endocrine disorders
0.000 0.482 0.518
H61.1 Non-infective disorders of pinna
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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