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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9271367
log Bayes Factor = 258.737
Chromosome 6   position 32,586,908  (GRCh37) Explore rs9271367 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
Z93.2 Ileostomy status
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
E10.4 With neurological complications
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
K51.4 Pseudopolyposis of colon
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
C44 Other malignant neoplasms of skin
0.998 0.002 0.000
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
K51.8 Other ulcerative colitis
0.998 0.002 0.000
D60-D64 Aplastic and other anaemias
0.000 0.004 0.996
D64.9 Anaemia, unspecified
0.000 0.005 0.995
D64 Other anaemias
0.000 0.005 0.995
K51.3 Ulcerative (chronic) rectosigmoiditis
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.008 0.992
E11.1 With ketoacidosis
0.000 0.009 0.991
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.012 0.988
K90 Intestinal malabsorption
0.000 0.013 0.987
G35-G37 Demyelinating diseases of the central nervous system
0.986 0.014 0.000
K51.2 Ulcerative (chronic) proctitis
0.986 0.014 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.015 0.985
L40-L45 Papulosquamous disorders
0.000 0.016 0.984
G37 Other demyelinating diseases of central nervous system
0.984 0.016 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.017 0.983
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.018 0.982
E05.9 Thyrotoxicosis, unspecified
0.000 0.019 0.981
L90.0 Lichen sclerosus et atrophicus
0.000 0.019 0.981
L90 Atrophic disorders of skin
0.000 0.019 0.981
L40 Psoriasis
0.000 0.019 0.981
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.020 0.980
G37.9 Demyelinating disease of central nervous system, unspecified
0.980 0.020 0.000
D50-D53 Nutritional anaemias
0.000 0.022 0.978
L40.9 Psoriasis, unspecified
0.000 0.025 0.975
H34 Retinal vascular occlusions
0.000 0.026 0.974
D50.9 Iron deficiency anaemia, unspecified
0.000 0.028 0.972
C44.1 Skin of eyelid, including canthus
0.972 0.028 0.000
D50 Iron deficiency anaemia
0.000 0.029 0.971
J43 Emphysema
0.000 0.030 0.970
J95-J99 Other diseases of the respiratory system
0.000 0.030 0.970
E10.5 With peripheral circulatory complications
0.000 0.030 0.970
K90-K93 Other diseases of the digestive system
0.000 0.033 0.967
Chapter XI Diseases of the digestive system
0.000 0.035 0.965
J86 Pyothorax
0.000 0.039 0.961
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.039 0.961
C44.7 Skin of lower limb, including hip
0.960 0.040 0.000
N18.9 Chronic renal failure, unspecified
0.000 0.047 0.953
N18 Chronic renal failure
0.000 0.051 0.949
E10.8 With unspecified complications
0.000 0.052 0.948
K70-K77 Diseases of liver
0.000 0.052 0.948
Chapter XIV Diseases of the genitourinary system
0.000 0.053 0.947
J43.9 Emphysema, unspecified
0.000 0.053 0.947
D80-D89 Certain disorders involving the immune mechanism
0.000 0.053 0.947
E11.2 With renal complications
0.000 0.055 0.945
N17-N19 Renal failure
0.000 0.057 0.943
H34.8 Other retinal vascular occlusions
0.000 0.058 0.942
N00-N08 Glomerular diseases
0.000 0.060 0.940
J98 Other respiratory disorders
0.000 0.060 0.940
K75 Other inflammatory liver diseases
0.000 0.066 0.934
D86 Sarcoidosis
0.000 0.067 0.933
L80 Vitiligo
0.000 0.068 0.932
K75.4 Autoimmune hepatitis
0.000 0.071 0.929
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.071 0.929
H43-H45 Disorders of vitreous body and globe
0.000 0.073 0.927
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.074 0.926
C44.9 Malignant neoplasm of skin, unspecified
0.926 0.074 0.000
E11.5 With peripheral circulatory complications
0.000 0.077 0.923
H35 Other retinal disorders
0.000 0.077 0.923
E20-E35 Disorders of other endocrine glands
0.000 0.078 0.922
H53-H54 Visual disturbances and blindness
0.000 0.078 0.922
E10.2 With renal complications
0.000 0.079 0.921
J86.9 Pyothorax without fistula
0.000 0.080 0.920
L92.0 Granuloma annulare
0.000 0.081 0.919
E10.0 With coma
0.000 0.083 0.917
E03.8 Other specified hypothyroidism
0.000 0.085 0.915
D86.9 Sarcoidosis, unspecified
0.000 0.086 0.914
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.091 0.909
L40.0 Psoriasis vulgaris
0.000 0.092 0.908
J46 Status asthmaticus
0.000 0.094 0.906
H43 Disorders of vitreous body
0.000 0.095 0.905
K86 Other diseases of pancreas
0.000 0.095 0.905
E11.3 With ophthalmic complications
0.000 0.096 0.904
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.103 0.897
E11.6 With other specified complications
0.000 0.107 0.893
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.119 0.881
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.120 0.880
H54 Blindness and low vision
0.000 0.121 0.879
J98.4 Other disorders of lung
0.000 0.125 0.875
K90.9 Intestinal malabsorption, unspecified
0.000 0.126 0.874
N40-N51 Diseases of male genital organs
0.000 0.127 0.873
J86.0 Pyothorax with fistula
0.000 0.129 0.871
C44.5 Skin of trunk
0.869 0.131 0.000
N48 Other disorders of penis
0.000 0.132 0.868
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.133 0.867
E14.8 With unspecified complications
0.000 0.135 0.865
K72 Hepatic failure, not elsewhere classified
0.000 0.136 0.864
N05 Unspecified nephritic syndrome
0.000 0.139 0.861
E24 Cushing's syndrome
0.000 0.141 0.859
K86.1 Other chronic pancreatitis
0.000 0.143 0.857
E10.6 With other specified complications
0.000 0.143 0.857
N04 Nephrotic syndrome
0.000 0.143 0.856
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.144 0.856
K51.5 Mucosal proctocolitis
0.855 0.145 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.145 0.855
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.146 0.854
H35.2 Other proliferative retinopathy
0.000 0.148 0.852
N18.2 Chronic kidney disease, stage 2
0.000 0.148 0.852
N48.6 Balanitis xerotica obliterans
0.000 0.154 0.846
H43.3 Other vitreous opacities
0.000 0.155 0.845
E13 Other specified diabetes mellitus
0.000 0.156 0.844
H35.8 Other specified retinal disorders
0.000 0.157 0.843
E16.1 Other hypoglycaemia
0.000 0.162 0.838
H54.7 Unspecified visual loss
0.000 0.165 0.835
N25-N29 Other disorders of kidney and ureter
0.000 0.167 0.833
N48.0 Leukoplakia of penis
0.000 0.168 0.832
K86.3 Pseudocyst of pancreas
0.000 0.169 0.831
K73 Chronic hepatitis, not elsewhere classified
0.000 0.169 0.831
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.827 0.173 0.000
K82 Other diseases of gallbladder
0.000 0.174 0.826
E27 Other disorders of adrenal gland
0.000 0.180 0.820
N48.1 Balanoposthitis
0.000 0.187 0.813
E14.6 With other specified complications
0.000 0.188 0.812
Chapter VIII Diseases of the ear and mastoid process
0.000 0.188 0.812
E65-E68 Obesity and other hyperalimentation
0.000 0.188 0.812
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.189 0.811
D62 Acute posthaemorrhagic anaemia
0.000 0.192 0.808
H43.8 Other disorders of vitreous body
0.000 0.193 0.807
J44 Other chronic obstructive pulmonary disease
0.000 0.196 0.804
H43.1 Vitreous haemorrhage
0.000 0.198 0.802
H60-H62 Diseases of external ear
0.000 0.202 0.798
H54.0 Blindness, both eyes
0.000 0.204 0.796
N04.9 Unspecified
0.000 0.204 0.796
J42 Unspecified chronic bronchitis
0.000 0.204 0.796
L10-L14 Bullous disorders
0.000 0.207 0.792
H34.2 Other retinal artery occlusions
0.000 0.208 0.792
J98.6 Disorders of diaphragm
0.000 0.208 0.792
E40-E46 Malnutrition
0.000 0.209 0.791
D86.8 Sarcoidosis of other and combined sites
0.000 0.210 0.790
K72.0 Acute and subacute hepatic failure
0.000 0.210 0.790
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.210 0.790
H61 Other disorders of external ear
0.000 0.213 0.787
C44.6 Skin of upper limb, including shoulder
0.787 0.213 0.000
H35.6 Retinal haemorrhage
0.000 0.215 0.785
E83 Disorders of mineral metabolism
0.784 0.216 0.000
E06 Thyroiditis
0.000 0.217 0.783
L40.1 Generalised pustular psoriasis
0.000 0.217 0.783
J85 Abscess of lung and mediastinum
0.000 0.218 0.782
E21.0 Primary hyperparathyroidism
0.000 0.222 0.778
H61.0 Perichondritis of external ear
0.000 0.222 0.778
E27.1 Primary adrenocortical insufficiency
0.000 0.225 0.775
N05.2 Diffuse membranous glomerulonephritis
0.000 0.226 0.774
L40.8 Other psoriasis
0.000 0.227 0.773
J43.2 Centrilobular emphysema
0.000 0.227 0.773
J98.8 Other specified respiratory disorders
0.000 0.230 0.770
E83.3 Disorders of phosphorus metabolism
0.769 0.231 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.239 0.761
N42 Other disorders of prostate
0.000 0.241 0.759
N18.3 Chronic kidney disease, stage 3
0.000 0.242 0.758
J95.0 Tracheostomy malfunction
0.000 0.243 0.757
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.244 0.756
E24.2 Drug-induced Cushing's syndrome
0.000 0.245 0.755
C44.4 Skin of scalp and neck
0.754 0.246 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.246 0.754
K82.8 Other specified diseases of gallbladder
0.000 0.247 0.753
L43 Lichen planus
0.000 0.248 0.752
E14.4 With neurological complications
0.000 0.253 0.747
E13.9 Without complications
0.000 0.254 0.746
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.255 0.745
N18.0 End-stage renal disease
0.000 0.255 0.745
K86.2 Cyst of pancreas
0.000 0.257 0.743
N28 Other disorders of kidney and ureter, not elsewhere classified
0.000 0.259 0.741
D80 Immunodeficiency with predominantly antibody defects
0.000 0.260 0.740
E66 Obesity
0.000 0.263 0.737
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.263 0.737
H35.4 Peripheral retinal degeneration
0.000 0.265 0.735
C44.0 Skin of lip
0.734 0.266 0.000
G36 Other acute disseminated demyelination
0.734 0.266 0.000
D53 Other nutritional anaemias
0.000 0.266 0.734
D86.1 Sarcoidosis of lymph nodes
0.000 0.267 0.733
N28.9 Disorder of kidney and ureter, unspecified
0.000 0.269 0.731
J45.1 Nonallergic asthma
0.000 0.276 0.724
H34.1 Central retinal artery occlusion
0.000 0.277 0.723
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.277 0.723
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.280 0.720
J98.2 Interstitial emphysema
0.000 0.282 0.718
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
H34.9 Retinal vascular occlusion, unspecified
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
G37.8 Other specified demyelinating diseases of central nervous system
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
C44.8 Overlapping lesion of skin
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
H35.0 Background retinopathy and retinal vascular changes
0.000 0.285 0.715
E14.5 With peripheral circulatory complications
0.000 0.285 0.715
K82.9 Disease of gallbladder, unspecified
0.000 0.285 0.715
K75.8 Other specified inflammatory liver diseases
0.000 0.285 0.714
E66.9 Obesity, unspecified
0.000 0.286 0.714
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.286 0.714
D64.4 Congenital dyserythropoietic anaemia
0.000 0.287 0.713
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.287 0.713
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.287 0.713
D64.0 Hereditary sideroblastic anaemia
0.000 0.287 0.713
K74 Fibrosis and cirrhosis of liver
0.000 0.287 0.713
N48.9 Disorder of penis, unspecified
0.000 0.289 0.711
K90.3 Pancreatic steatorrhoea
0.000 0.292 0.708
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.292 0.708
K90.1 Tropical sprue
0.000 0.292 0.708
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.293 0.707
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.293 0.706
L87 Transepidermal elimination disorders
0.000 0.293 0.706
L86 Keratoderma in diseases classified elsewhere
0.000 0.293 0.706
N05.9 Unspecified
0.000 0.294 0.706
J98.9 Respiratory disorder, unspecified
0.000 0.294 0.706
N18.8 Other chronic renal failure
0.000 0.295 0.705
L44 Other papulosquamous disorders
0.000 0.295 0.705
L41 Parapsoriasis
0.000 0.295 0.705
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.295 0.705
G37.5 Concentric sclerosis [Balo]
0.705 0.295 0.000
G37.4 Subacute necrotising myelitis
0.705 0.295 0.000
G37.2 Central pontine myelinolysis
0.705 0.295 0.000
G37.1 Central demyelination of corpus callosum
0.705 0.295 0.000
G37.0 Diffuse sclerosis
0.705 0.295 0.000
L90.9 Atrophic disorder of skin, unspecified
0.000 0.296 0.703
L90.6 Striae atrophicae
0.000 0.296 0.703
L90.4 Acrodermatitis chronica atrophicans
0.000 0.296 0.703
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.296 0.703
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.296 0.703
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.296 0.703
L40.4 Guttate psoriasis
0.000 0.297 0.703
L40.3 Pustulosis palmaris et plantaris
0.000 0.297 0.703
L40.2 Acrodermatitis continua
0.000 0.297 0.703
L13 Other bullous disorders
0.000 0.298 0.702
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.300 0.700
H34.0 Transient retinal artery occlusion
0.000 0.302 0.698
H54.2 Low vision, both eyes
0.000 0.302 0.698
N25 Disorders resulting from impaired renal tubular function
0.000 0.303 0.696
D50.1 Sideropenic dysphagia
0.000 0.303 0.696
J43.1 Panlobular emphysema
0.000 0.304 0.696
J43.0 MacLeod's syndrome
0.000 0.304 0.696
J96 Respiratory failure, not elsewhere classified
0.000 0.304 0.696
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.307 0.693
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.307 0.693
E21.3 Hyperparathyroidism, unspecified
0.000 0.311 0.689
J45.8 Mixed asthma
0.000 0.311 0.689
D83 Common variable immunodeficiency
0.000 0.311 0.689
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.311 0.689
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.311 0.689
K71 Toxic liver disease
0.000 0.320 0.680
K77 Liver disorders in diseases classified elsewhere
0.000 0.320 0.680
D82 Immunodeficiency associated with other major defects
0.000 0.321 0.679
D81 Combined immunodeficiencies
0.000 0.321 0.679
H35.5 Hereditary retinal dystrophy
0.000 0.323 0.677
K86.8 Other specified diseases of pancreas
0.000 0.323 0.677
H54.1 Blindness, one eye, low vision, other eye
0.000 0.323 0.677
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.324 0.676
J41 Simple and mucopurulent chronic bronchitis
0.000 0.325 0.675
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.326 0.674
N06 Isolated proteinuria with specified morphological lesion
0.000 0.326 0.674
N01 Rapidly progressive nephritic syndrome
0.000 0.326 0.674
N00 Acute nephritic syndrome
0.000 0.326 0.674
J85.2 Abscess of lung without pneumonia
0.000 0.326 0.674
J98.3 Compensatory emphysema
0.000 0.326 0.674
E20 Hypoparathyroidism
0.000 0.328 0.672
K72.1 Chronic hepatic failure
0.000 0.330 0.670
K75.2 Nonspecific reactive hepatitis
0.000 0.331 0.669
K75.1 Phlebitis of portal vein
0.000 0.331 0.669
D86.3 Sarcoidosis of skin
0.000 0.331 0.669
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.334 0.666
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.334 0.666
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.334 0.666
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.334 0.666
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.335 0.664
H35.1 Retinopathy of prematurity
0.000 0.338 0.661
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.339 0.661
E32 Diseases of thymus
0.000 0.339 0.661
E31 Polyglandular dysfunction
0.000 0.339 0.661
E30 Disorders of puberty, not elsewhere classified
0.000 0.339 0.661
E29 Testicular dysfunction
0.000 0.340 0.660
K82.3 Fistula of gallbladder
0.000 0.345 0.655
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.345 0.655
E11.8 With unspecified complications
0.000 0.345 0.655
H30 Chorioretinal inflammation
0.000 0.348 0.652
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.348 0.651
H61.8 Other specified disorders of external ear
0.000 0.349 0.651
N42.8 Other specified disorders of prostate
0.000 0.351 0.649
K73.9 Chronic hepatitis, unspecified
0.000 0.352 0.648
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.354 0.646
N04.1 Focal and segmental glomerular lesions
0.000 0.354 0.646
N05.1 Focal and segmental glomerular lesions
0.000 0.356 0.644
H43.2 Crystalline deposits in vitreous body
0.000 0.356 0.644
E07 Other disorders of thyroid
0.000 0.357 0.643
K51.0 Ulcerative (chronic) enterocolitis
0.643 0.357 0.000
L94 Other localised connective tissue disorders
0.000 0.358 0.642
E46 Unspecified protein-energy malnutrition
0.000 0.359 0.641
K82.2 Perforation of gallbladder
0.000 0.360 0.640
N05.8 Other
0.000 0.361 0.639
L13.0 Dermatitis herpetiformis
0.000 0.362 0.638
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.363 0.636
J43.8 Other emphysema
0.000 0.364 0.636
D64.3 Other sideroblastic anaemias
0.000 0.364 0.636
H43.0 Vitreous prolapse
0.000 0.365 0.635
E83.9 Disorder of mineral metabolism, unspecified
0.633 0.367 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.367 0.633
E21.4 Other specified disorders of parathyroid gland
0.000 0.369 0.631
E28 Ovarian dysfunction
0.000 0.369 0.631
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.369 0.631
H54.3 Unqualified visual loss, both eyes
0.000 0.370 0.630
E05.8 Other thyrotoxicosis
0.000 0.372 0.627
H61.3 Acquired stenosis of external ear canal
0.000 0.374 0.626
D86.0 Sarcoidosis of lung
0.000 0.375 0.625
H54.5 Low vision, one eye
0.000 0.377 0.623
N42.2 Atrophy of prostate
0.000 0.378 0.622
N18.4 Chronic kidney disease, stage 4
0.000 0.379 0.621
J45.0 Predominantly allergic asthma
0.000 0.379 0.621
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.381 0.618
N05.6 Dense deposit disease
0.000 0.382 0.617
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.382 0.617
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.382 0.617
N05.0 Minor glomerular abnormality
0.000 0.382 0.617
K72.9 Hepatic failure, unspecified
0.000 0.383 0.617
D51 Vitamin B12 deficiency anaemia
0.000 0.384 0.616
E24.8 Other Cushing's syndrome
0.000 0.384 0.616
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.384 0.616
E24.3 Ectopic ACTH syndrome
0.000 0.384 0.616
E24.1 Nelson's syndrome
0.000 0.384 0.616
E24.0 Pituitary-dependent Cushing's disease
0.000 0.384 0.616
K90.8 Other intestinal malabsorption
0.000 0.384 0.616
K74.6 Other and unspecified cirrhosis of liver
0.000 0.384 0.616
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.385 0.614
H53 Visual disturbances
0.000 0.386 0.614
N04.8 Other
0.000 0.386 0.614
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.386 0.614
N04.6 Dense deposit disease
0.000 0.386 0.614
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.386 0.614
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.386 0.614
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.386 0.614
N04.2 Diffuse membranous glomerulonephritis
0.000 0.386 0.614
N18.1 Chronic kidney disease, stage 1
0.000 0.389 0.611
H60 Otitis externa
0.000 0.390 0.610
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.391 0.609
K51.1 Ulcerative (chronic) ileocolitis
0.609 0.391 0.000
E06.3 Autoimmune thyroiditis
0.000 0.393 0.607
E13.8 With unspecified complications
0.000 0.394 0.605
E13.7 With multiple complications
0.000 0.394 0.605
E13.6 With other specified complications
0.000 0.394 0.605
E13.5 With peripheral circulatory complications
0.000 0.394 0.605
E13.4 With neurological complications
0.000 0.394 0.605
E13.2 With renal complications
0.000 0.394 0.605
E13.1 With ketoacidosis
0.000 0.394 0.605
E13.0 With coma
0.000 0.394 0.605
K74.0 Hepatic fibrosis
0.000 0.395 0.605
K82.0 Obstruction of gallbladder
0.000 0.395 0.605
N42.9 Disorder of prostate, unspecified
0.000 0.395 0.605
H80-H83 Diseases of inner ear
0.000 0.396 0.604
L90.8 Other atrophic disorders of skin
0.000 0.396 0.604
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.399 0.601
N49.2 Inflammatory disorders of scrotum
0.000 0.400 0.600
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.000 0.403 0.596
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.404 0.596
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.404 0.596
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.404 0.596
H54.6 Unqualified visual loss, one eye
0.000 0.408 0.592
E25 Adrenogenital disorders
0.000 0.408 0.592
N42.1 Congestion and haemorrhage of prostate
0.000 0.409 0.591
C44.2 Skin of ear and external auricular canal
0.590 0.410 0.000
E06.9 Thyroiditis, unspecified
0.000 0.411 0.589
E27.5 Adrenomedullary hyperfunction
0.000 0.412 0.588
E27.0 Other adrenocortical overactivity
0.000 0.412 0.588
N48.5 Ulcer of penis
0.000 0.414 0.586
D63.0 Anaemia in neoplastic disease
0.000 0.417 0.583
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.417 0.582
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.418 0.582
E67 Other hyperalimentation
0.000 0.418 0.582
E68 Sequelae of hyperalimentation
0.000 0.418 0.582
J95.5 Postprocedural subglottic stenosis
0.000 0.418 0.581
J95.4 Mendelson's syndrome
0.000 0.418 0.581
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.418 0.581
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.418 0.581
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.418 0.581
H53.1 Subjective visual disturbances
0.000 0.421 0.579
N04.0 Minor glomerular abnormality
0.000 0.421 0.578
N25.8 Other disorders resulting from impaired renal tubular function
0.000 0.422 0.578
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.423 0.577
H61.9 Disorder of external ear, unspecified
0.000 0.423 0.577
E27.8 Other specified disorders of adrenal gland
0.000 0.427 0.573
E13.3 With ophthalmic complications
0.000 0.427 0.573
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.427 0.572
J33 Nasal polyp
0.000 0.428 0.572
J33.9 Nasal polyp, unspecified
0.000 0.431 0.569
E21.2 Other hyperparathyroidism
0.000 0.432 0.568
L10 Pemphigus
0.000 0.432 0.568
L14 Bullous disorders in diseases classified elsewhere
0.000 0.432 0.568
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.433 0.567
E45 Retarded development following protein-energy malnutrition
0.000 0.433 0.567
E43 Unspecified severe protein-energy malnutrition
0.000 0.433 0.567
E42 Marasmic kwashiorkor
0.000 0.433 0.567
E41 Nutritional marasmus
0.000 0.433 0.567
E40 Kwashiorkor
0.000 0.433 0.567
E26 Hyperaldosteronism
0.000 0.434 0.565
L43.8 Other lichen planus
0.000 0.435 0.564
L43.9 Lichen planus, unspecified
0.000 0.437 0.563
J85.0 Gangrene and necrosis of lung
0.000 0.437 0.562
E83.8 Other disorders of mineral metabolism
0.562 0.437 0.000
E83.2 Disorders of zinc metabolism
0.562 0.437 0.000
E83.0 Disorders of copper metabolism
0.562 0.437 0.000
K50-K52 Noninfective enteritis and colitis
0.404 0.438 0.158
E06.5 Other chronic thyroiditis
0.000 0.438 0.562
E06.4 Drug-induced thyroiditis
0.000 0.438 0.562
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.438 0.562
E06.1 Subacute thyroiditis
0.000 0.438 0.562
E06.0 Acute thyroiditis
0.000 0.438 0.562
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.439 0.561
E11.4 With neurological complications
0.000 0.439 0.561
J85.3 Abscess of mediastinum
0.000 0.439 0.560
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.440 0.559
D53.9 Nutritional anaemia, unspecified
0.000 0.442 0.558
N44 Torsion of testis
0.000 0.445 0.554
J33.0 Polyp of nasal cavity
0.000 0.447 0.553
G36.0 Neuromyelitis optica [Devic]
0.553 0.447 0.000
N27 Small kidney of unknown cause
0.000 0.448 0.552
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.448 0.551
H31 Other disorders of choroid
0.000 0.453 0.547
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.455 0.545
N42.3 Dysplasia of prostate
0.000 0.456 0.544
E11.0 With coma
0.000 0.456 0.544
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.456 0.544
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.457 0.542
H80 Otosclerosis
0.000 0.458 0.542
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.000 0.458 0.541
H53.0 Amblyopia ex anopsia
0.000 0.458 0.542
L43.3 Subacute (active) lichen planus
0.000 0.461 0.539
L43.2 Lichenoid drug reaction
0.000 0.461 0.539
L43.1 Bullous lichen planus
0.000 0.461 0.539
L43.0 Hypertrophic lichen planus
0.000 0.461 0.539
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.461 0.539
N25.9 Disorder resulting from impaired renal tubular function, unspecified
0.000 0.466 0.534
L11 Other acantholytic disorders
0.000 0.466 0.534
N48.3 Priapism
0.000 0.467 0.533
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.469 0.531
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.469 0.531
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.469 0.531
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.469 0.531
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.469 0.531
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.469 0.531
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.470 0.530
N26 Unspecified contracted kidney
0.000 0.470 0.530
E66.1 Drug-induced obesity
0.000 0.471 0.529
E27.9 Disorder of adrenal gland, unspecified
0.000 0.472 0.528
J30-J39 Other diseases of upper respiratory tract
0.000 0.472 0.528
G36.9 Acute disseminated demyelination, unspecified
0.526 0.474 0.000
G36.8 Other specified acute disseminated demyelination
0.526 0.474 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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