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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0102
log Bayes Factor = 99.5678
contains 5 variants:
rs76335573
lBF = 12.493
Chr 1 : 107,687,605
rs10999556
lBF = 11.158
Chr10 : 72,571,360
rs77657273
lBF = 15.122
Chr14 : 35,139,957
rs61988316
lBF = 17.526
Chr14 : 35,888,993
rs116954357
lBF = 6.547
Chr19 : 20,223,681
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I50.1 Left ventricular failure
1.000 0.000 0.000
M19.9 Arthrosis, unspecified
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I45 Other conduction disorders
1.000 0.000 0.000
M19 Other arthrosis
1.000 0.000 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
I45.1 Other and unspecified right bundle-branch block
1.000 0.000 0.000
I50.0 Congestive heart failure
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
M19.94 Arthrosis, unspecified (Hand)
1.000 0.000 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.999 0.001 0.000
M54.5 Low back pain
0.999 0.001 0.000
M18 Arthrosis of first carpometacarpal joint
0.999 0.001 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.999 0.001 0.000
I51 Complications and ill-defined descriptions of heart disease
0.999 0.001 0.000
M24 Other specific joint derangements
0.999 0.001 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.999 0.001 0.000
Z36 Antenatal screening
0.998 0.002 0.000
I51.7 Cardiomegaly
0.998 0.002 0.000
B95-B98 Bacterial, viral and other infectious agents
0.998 0.002 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.997 0.003 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.996 0.004 0.000
M31 Other necrotising vasculopathies
0.996 0.004 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.995 0.005 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.995 0.005 0.000
F30-F39 Mood [affective] disorders
0.995 0.005 0.000
M54.9 Dorsalgia, unspecified
0.994 0.006 0.000
I34 Nonrheumatic mitral valve disorders
0.994 0.006 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.994 0.006 0.000
G20-G26 Extrapyramidal and movement disorders
0.994 0.006 0.000
M54.59 Low back pain (Site unspecified)
0.994 0.006 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.994 0.006 0.000
M54.56 Low back pain (Lumbar region)
0.993 0.007 0.000
Z35 Supervision of high-risk pregnancy
0.992 0.008 0.000
M21 Other acquired deformities of limbs
0.992 0.008 0.000
M31.6 Other giant cell arteritis
0.991 0.009 0.000
O36 Maternal care for other known or suspected foetal problems
0.991 0.009 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.990 0.010 0.000
M25 Other joint disorders, not elsewhere classified
0.990 0.010 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.990 0.010 0.000
O26.8 Other specified pregnancy-related conditions
0.989 0.011 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.989 0.011 0.000
G20 Parkinson's disease
0.989 0.011 0.000
I42 Cardiomyopathy
0.989 0.011 0.000
W00-W19 Falls
0.987 0.013 0.000
T42.4 Benzodiazepines
0.987 0.013 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.987 0.013 0.000
M65-M68 Disorders of synovium and tendon
0.987 0.013 0.000
M80-M85 Disorders of bone density and structure
0.987 0.013 0.000
M86-M90 Other osteopathies
0.984 0.016 0.000
O42 Premature rupture of membranes
0.984 0.016 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.984 0.016 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.983 0.017 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.983 0.017 0.000
F03 Unspecified dementia
0.983 0.017 0.000
Y52 Agents primarily affecting the cardiovascular system
0.982 0.018 0.000
I50.9 Heart failure, unspecified
0.980 0.020 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.980 0.020 0.000
M23 Internal derangement of knee
0.980 0.020 0.000
Z74 Problems related to care-provider dependency
0.980 0.020 0.000
I31 Other diseases of pericardium
0.978 0.022 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.977 0.023 0.000
F32 Depressive episode
0.977 0.023 0.000
I44 Atrioventricular and left bundle-branch block
0.974 0.026 0.000
M24.2 Disorder of ligament
0.974 0.026 0.000
O00-O08 Pregnancy with abortive outcome
0.973 0.027 0.000
M25.8 Other specified joint disorders
0.973 0.027 0.000
F32.9 Depressive episode, unspecified
0.973 0.027 0.000
M45-M49 Spondylopathies
0.972 0.028 0.000
Z36.9 Antenatal screening, unspecified
0.970 0.030 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.967 0.033 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.966 0.034 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.966 0.034 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.963 0.036 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.963 0.037 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.963 0.037 0.000
I05-I09 Chronic rheumatic heart diseases
0.961 0.039 0.000
O85-O92 Complications predominantly related to the puerperium
0.960 0.040 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.960 0.040 0.000
O42.9 Premature rupture of membranes, unspecified
0.959 0.041 0.000
V80-V89 Other land transport accidents
0.959 0.041 0.000
X60-X84 Intentional self-harm
0.956 0.044 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.955 0.045 0.000
M19.0 Primary arthrosis of other joints
0.955 0.045 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.955 0.045 0.000
I27 Other pulmonary heart diseases
0.955 0.045 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.955 0.045 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.955 0.045 0.000
M89 Other disorders of bone
0.953 0.047 0.000
I31.3 Pericardial effusion (noninflammatory)
0.952 0.048 0.000
O03 Spontaneous abortion
0.950 0.050 0.000
W19 Unspecified fall
0.950 0.050 0.000
Y42.7 Androgens and anabolic congeners
0.950 0.050 0.000
O36.5 Maternal care for poor foetal growth
0.948 0.052 0.000
Y43 Primarily systemic agents
0.947 0.053 0.000
Z74.0 Reduced mobility
0.946 0.054 0.000
T79-T79 Certain early complications of trauma
0.945 0.055 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.945 0.055 0.000
O03.9 Complete or unspecified, without complication
0.943 0.057 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.942 0.058 0.000
M81 Osteoporosis without pathological fracture
0.940 0.060 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.939 0.061 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.938 0.062 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.938 0.062 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.937 0.063 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.936 0.064 0.000
Z32 Pregnancy examination and test
0.936 0.064 0.000
F99-F99 Unspecified mental disorder
0.936 0.064 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.935 0.065 0.000
M65 Synovitis and tenosynovitis
0.935 0.065 0.000
T93 Sequelae of injuries of lower limb
0.935 0.065 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.932 0.068 0.000
Z35.8 Supervision of other high-risk pregnancies
0.931 0.069 0.000
I08 Multiple valve diseases
0.930 0.070 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.930 0.070 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.929 0.071 0.000
O30 Multiple gestation
0.928 0.072 0.000
M54.1 Radiculopathy
0.928 0.072 0.000
I45.5 Other specified heart block
0.928 0.072 0.000
I42.0 Dilated cardiomyopathy
0.928 0.072 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.926 0.074 0.000
M67 Other disorders of synovium and tendon
0.926 0.074 0.000
I44.7 Left bundle-branch block, unspecified
0.925 0.075 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.925 0.075 0.000
M24.1 Other articular cartilage disorders
0.921 0.079 0.000
F52.2 Failure of genital response
0.919 0.081 0.000
I34.1 Mitral (valve) prolapse
0.918 0.082 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.918 0.082 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.918 0.082 0.000
I44.0 Atrioventricular block, first degree
0.918 0.082 0.000
M05-M14 Inflammatory polyarthropathies
0.918 0.082 0.000
W18 Other fall on same level
0.917 0.083 0.000
B35-B49 Mycoses
0.917 0.083 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.916 0.084 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.916 0.084 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.916 0.084 0.000
S10-S19 Injuries to the neck
0.916 0.084 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.915 0.085 0.000
M45 Ankylosing spondylitis
0.914 0.086 0.000
I47 Paroxysmal tachycardia
0.914 0.086 0.000
O86 Other puerperal infections
0.913 0.087 0.000
W19.2 School, other institution and public administrative area
0.913 0.087 0.000
Y42.5 Other oestrogens and progestogens
0.912 0.088 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.911 0.089 0.000
Z39 Postpartum care and examination
0.911 0.089 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.911 0.089 0.000
S40-S49 Injuries to the shoulder and upper arm
0.911 0.089 0.000
O00 Ectopic pregnancy
0.910 0.090 0.000
I30 Acute pericarditis
0.910 0.090 0.000
O80-O84 Delivery
0.909 0.091 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.909 0.091 0.000
I27.2 Other secondary pulmonary hypertension
0.908 0.092 0.000
I42.8 Other cardiomyopathies
0.908 0.092 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.908 0.092 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.907 0.093 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.907 0.093 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.906 0.094 0.000
M54.3 Sciatica
0.904 0.096 0.000
Z76 Persons encountering health services in other circumstances
0.902 0.098 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.902 0.098 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.901 0.099 0.000
O44 Placenta praevia
0.900 0.100 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.900 0.100 0.000
T87 Complications peculiar to reattachment and amputation
0.900 0.100 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.900 0.100 0.000
I47.2 Ventricular tachycardia
0.898 0.102 0.000
M21.2 Flexion deformity
0.898 0.102 0.000
Q80-Q89 Other congenital malformations
0.897 0.103 0.000
I33 Acute and subacute endocarditis
0.897 0.103 0.000
G54 Nerve root and plexus disorders
0.897 0.103 0.000
M23.4 Loose body in knee
0.896 0.104 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.895 0.105 0.000
Z32.1 Pregnancy confirmed
0.894 0.106 0.000
Chapter XXII Codes for special purposes
0.893 0.107 0.000
M24.26 Disorder of ligament (Lower leg)
0.893 0.107 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.891 0.109 0.000
I34.0 Mitral (valve) insufficiency
0.891 0.109 0.000
T86 Failure and rejection of transplanted organs and tissues
0.890 0.110 0.000
F99 Mental disorder, not otherwise specified
0.890 0.110 0.000
M89.9 Disorder of bone, unspecified
0.890 0.110 0.000
Y43.0 Antiallergic and antiemetic drugs
0.889 0.111 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.889 0.111 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.888 0.112 0.000
M21.6 Other acquired deformities of ankle and foot
0.888 0.112 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.888 0.112 0.000
I51.0 Cardiac septal defect, acquired
0.887 0.112 0.000
Y43.4 Immunosuppressive agents
0.887 0.113 0.000
I27.0 Primary pulmonary hypertension
0.887 0.113 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.886 0.114 0.000
S00-S09 Injuries to the head
0.882 0.118 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.882 0.118 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.882 0.118 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.882 0.118 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.881 0.119 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.881 0.119 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.880 0.120 0.000
M54.12 Radiculopathy (Cervical region)
0.879 0.121 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.879 0.121 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.879 0.121 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.878 0.122 0.000
T90 Sequelae of injuries of head
0.878 0.122 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.877 0.123 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.877 0.123 0.000
O30.0 Twin pregnancy
0.877 0.123 0.000
O23 Infections of genito-urinary tract in pregnancy
0.876 0.124 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.876 0.124 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.875 0.125 0.000
T40.2 Other opioids
0.875 0.125 0.000
Z74.1 Need for assistance with personal care
0.875 0.125 0.000
M81.9 Osteoporosis, unspecified
0.874 0.126 0.000
E10-E14 Diabetes mellitus
0.873 0.127 0.000
M25.7 Osteophyte
0.873 0.127 0.000
M23.3 Other meniscus derangements
0.872 0.128 0.000
W50-W64 Exposure to animate mechanical forces
0.872 0.128 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.871 0.129 0.000
O86.4 Pyrexia of unknown origin following delivery
0.871 0.129 0.000
Z39.1 Care and examination of lactating mother
0.868 0.132 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.867 0.133 0.000
M54.4 Lumbago with sciatica
0.867 0.133 0.000
I38 Endocarditis, valve unspecified
0.866 0.134 0.000
M82 Osteoporosis in diseases classified elsewhere
0.866 0.134 0.000
M00-M03 Infectious arthropathies
0.865 0.135 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.865 0.135 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.865 0.135 0.000
O82 Single delivery by Caesarean section
0.865 0.135 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.863 0.137 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.862 0.138 0.000
I08.0 Disorders of both mitral and aortic valves
0.862 0.138 0.000
M33 Dermatopolymyositis
0.861 0.138 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.861 0.139 0.000
Z35.5 Supervision of elderly primigravida
0.860 0.140 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.860 0.140 0.000
I77 Other disorders of arteries and arterioles
0.859 0.141 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.859 0.141 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.858 0.142 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.857 0.143 0.000
M54.39 Sciatica (Site unspecified)
0.856 0.144 0.000
M54.8 Other dorsalgia
0.856 0.144 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.856 0.144 0.000
G58 Other mononeuropathies
0.856 0.144 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.856 0.144 0.000
I72 Other aneurysm
0.855 0.145 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.855 0.145 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.855 0.145 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.855 0.145 0.000
M21.1 Varus deformity, not elsewhere classified
0.855 0.145 0.000
D60-D64 Aplastic and other anaemias
0.855 0.145 0.000
M47 Spondylosis
0.854 0.146 0.000
S00 Superficial injury of head
0.854 0.146 0.000
W18.3 Sports and athletics area
0.851 0.149 0.000
O36.4 Maternal care for intra-uterine death
0.849 0.151 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.849 0.151 0.000
I42.6 Alcoholic cardiomyopathy
0.849 0.151 0.000
W06 Fall involving bed
0.849 0.151 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.848 0.152 0.000
E14 Unspecified diabetes mellitus
0.848 0.152 0.000
M23.0 Cystic meniscus
0.848 0.152 0.000
I30.9 Acute pericarditis, unspecified
0.845 0.155 0.000
I10-I15 Hypertensive diseases
0.845 0.155 0.000
W20-W49 Exposure to inanimate mechanical forces
0.845 0.155 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.844 0.156 0.000
M21.0 Valgus deformity, not elsewhere classified
0.843 0.157 0.000
S90-S99 Injuries to the ankle and foot
0.843 0.157 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.843 0.157 0.000
T98 Sequelae of other and unspecified effects of external causes
0.843 0.157 0.000
O60-O75 Complications of labour and delivery
0.843 0.157 0.000
I45.3 Trifascicular block
0.842 0.158 0.000
Y40 Systemic antibiotics
0.842 0.158 0.000
G03 Meningitis due to other and unspecified causes
0.842 0.158 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.842 0.158 0.000
M60-M63 Disorders of muscles
0.842 0.158 0.000
B00 Herpesviral [herpes simplex] infections
0.839 0.161 0.000
M06 Other rheumatoid arthritis
0.839 0.161 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.839 0.161 0.000
G30-G32 Other degenerative diseases of the nervous system
0.839 0.161 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.838 0.162 0.000
X41.9 Unspecified place
0.838 0.162 0.000
W17 Other fall from one level to another
0.837 0.163 0.000
M23.49 Loose body in knee-Unspec lig/men
0.836 0.164 0.000
M24.23 Disorder of ligament (Forearm)
0.836 0.164 0.000
G90-G99 Other disorders of the nervous system
0.835 0.165 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.835 0.165 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.835 0.165 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.835 0.165 0.000
T45.0 Antiallergic and antiemetic drugs
0.834 0.166 0.000
O14.9 Preeclampsia, unspecified
0.832 0.168 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.832 0.168 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.831 0.169 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.830 0.170 0.000
M40-M43 Deforming dorsopathies
0.830 0.170 0.000
O44.1 Placenta praevia with haemorrhage
0.830 0.170 0.000
F39 Unspecified mood [affective] disorder
0.829 0.171 0.000
E00-E07 Disorders of thyroid gland
0.829 0.171 0.000
I45.8 Other specified conduction disorders
0.829 0.171 0.000
S00.0 Superficial injury of scalp
0.829 0.171 0.000
F30 Manic episode
0.828 0.171 0.000
M23.9 Internal derangement of knee, unspecified
0.826 0.174 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.826 0.174 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.826 0.174 0.000
M24.0 Loose body in joint
0.825 0.175 0.000
I36 Nonrheumatic tricuspid valve disorders
0.824 0.176 0.000
I33.0 Acute and subacute infective endocarditis
0.823 0.177 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.822 0.178 0.000
M21.4 Flat foot [pes planus] (acquired)
0.822 0.178 0.000
M47.2 Other spondylosis with radiculopathy
0.822 0.178 0.000
M25.9 Joint disorder, unspecified
0.821 0.178 0.000
Z56 Problems related to employment and unemployment
0.821 0.179 0.000
Z63 Other problems related to primary support group, including family circumstances
0.821 0.179 0.000
V40-V49 Car occupant injured in transport accident
0.821 0.179 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.821 0.179 0.000
M87 Osteonecrosis
0.820 0.179 0.000
V10-V19 Pedal cyclist injured in transport accident
0.820 0.180 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.820 0.180 0.000
T91 Sequelae of injuries of neck and trunk
0.819 0.181 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.819 0.181 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.819 0.181 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.818 0.182 0.000
X50-X57 Overexertion, travel and privation
0.818 0.182 0.000
M84 Disorders of continuity of bone
0.818 0.182 0.000
I77.0 Arteriovenous fistula, acquired
0.818 0.182 0.000
A15-A19 Tuberculosis
0.817 0.183 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.817 0.183 0.000
Z31 Procreative management
0.817 0.183 0.000
S60-S69 Injuries to the wrist and hand
0.817 0.183 0.000
M23.8 Other internal derangements of knee
0.816 0.184 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.816 0.184 0.000
I45.9 Conduction disorder, unspecified
0.816 0.184 0.000
T88.5 Other complications of anaesthesia
0.816 0.184 0.000
D61 Other aplastic anaemias
0.816 0.184 0.000
M80 Osteoporosis with pathological fracture
0.816 0.184 0.000
T86.1 Kidney transplant failure and rejection
0.814 0.186 0.000
M35 Other systemic involvement of connective tissue
0.814 0.186 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.814 0.186 0.000
T58 Toxic effect of carbon monoxide
0.814 0.186 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.814 0.186 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.813 0.187 0.000
M24.5 Contracture of joint
0.813 0.187 0.000
M46 Other inflammatory spondylopathies
0.812 0.188 0.000
B49 Unspecified mycosis
0.812 0.188 0.000
M25.86 Other specified joint disorders (Lower leg)
0.811 0.189 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.811 0.189 0.000
D75 Other diseases of blood and blood-forming organs
0.811 0.189 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.810 0.190 0.000
T20 Burn and corrosion of head and neck
0.810 0.190 0.000
M70-M79 Other soft tissue disorders
0.810 0.190 0.000
O00.1 Tubal pregnancy
0.809 0.191 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.809 0.191 0.000
G24 Dystonia
0.809 0.191 0.000
G58.8 Other specified mononeuropathies
0.809 0.191 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.808 0.192 0.000
M88 Paget's disease of bone [osteitis deformans]
0.807 0.193 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.807 0.193 0.000
T87.6 Other and unspecified complications of amputation stump
0.807 0.193 0.000
O82.1 Delivery by emergency Caesarean section
0.806 0.194 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.806 0.194 0.000
T17 Foreign body in respiratory tract
0.806 0.194 0.000
Q76 Congenital malformations of spine and bony thorax
0.805 0.195 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.805 0.195 0.000
I31.9 Disease of pericardium, unspecified
0.805 0.195 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.805 0.195 0.000
I42.2 Other hypertrophic cardiomyopathy
0.804 0.196 0.000
M22 Disorders of patella
0.803 0.197 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.803 0.197 0.000
M54.19 Radiculopathy (Site unspecified)
0.802 0.198 0.000
E14.9 Without complications
0.802 0.198 0.000
I08.8 Other multiple valve diseases
0.802 0.198 0.000
X20-X29 Contact with venomous animals and plants
0.801 0.199 0.000
E20-E35 Disorders of other endocrine glands
0.801 0.199 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.801 0.199 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.800 0.200 0.000
T36 Poisoning by systemic antibiotics
0.800 0.200 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.800 0.200 0.000
I77.6 Arteritis, unspecified
0.800 0.200 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.800 0.200 0.000
Z76.9 Persons encountering health services in unspecified circumstances
0.800 0.200 0.000
E07 Other disorders of thyroid
0.800 0.200 0.000
I46 Cardiac arrest
0.800 0.200 0.000
M25.3 Other instability of joint
0.800 0.200 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.799 0.201 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.799 0.201 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.799 0.201 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.799 0.201 0.000
F32.0 Mild depressive episode
0.798 0.202 0.000
O26.2 Pregnancy care of habitual aborter
0.797 0.203 0.000
T93.1 Sequelae of fracture of femur
0.797 0.203 0.000
G54.0 Brachial plexus disorders
0.796 0.204 0.000
T93.0 Sequelae of open wound of lower limb
0.796 0.204 0.000
O00.9 Ectopic pregnancy, unspecified
0.795 0.205 0.000
F02 Dementia in other diseases classified elsewhere
0.795 0.205 0.000
F33 Recurrent depressive disorder
0.795 0.205 0.000
O87 Venous complications in the puerperium
0.794 0.206 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.793 0.206 0.000
M89.0 Algoneurodystrophy
0.793 0.207 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.793 0.207 0.000
W19.1 Residential institution
0.792 0.208 0.000
E16 Other disorders of pancreatic internal secretion
0.791 0.209 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.791 0.209 0.000
Y85 Sequelae of transport accidents
0.791 0.209 0.000
Q24 Other congenital malformations of heart
0.791 0.209 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.791 0.209 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.791 0.209 0.000
S62 Fracture at wrist and hand level
0.789 0.211 0.000
I27.8 Other specified pulmonary heart diseases
0.789 0.211 0.000
X10-X19 Contact with heat and hot substances
0.789 0.211 0.000
O16 Unspecified maternal hypertension
0.789 0.211 0.000
V89.9 Person injured in unspecified vehicle accident
0.788 0.212 0.000
D61.9 Aplastic anaemia, unspecified
0.788 0.212 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.788 0.212 0.000
M24.24 Disorder of ligament (Hand)
0.788 0.212 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.787 0.213 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.787 0.213 0.000
T23 Burn and corrosion of wrist and hand
0.786 0.214 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.786 0.214 0.000
F31 Bipolar affective disorder
0.786 0.214 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.785 0.215 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.785 0.215 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.785 0.215 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.785 0.215 0.000
M19.2 Other secondary arthrosis
0.784 0.216 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.784 0.216 0.000
G30 Alzheimer's disease
0.783 0.217 0.000
Z73 Problems related to life-management difficulty
0.783 0.217 0.000
M67.4 Ganglion
0.782 0.218 0.000
T92 Sequelae of injuries of upper limb
0.781 0.219 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.781 0.219 0.000
S90 Superficial injury of ankle and foot
0.781 0.219 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.781 0.219 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.780 0.220 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.780 0.220 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.780 0.220 0.000
M82.1 Osteoporosis in endocrine disorders
0.780 0.220 0.000
Z63.0 Problems in relationship with spouse or partner
0.780 0.220 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.779 0.220 0.000
M25.88 Other specified joint disorders (Other)
0.779 0.221 0.000
D80-D89 Certain disorders involving the immune mechanism
0.779 0.221 0.000
E07.8 Other specified disorders of thyroid
0.778 0.222 0.000
M54.37 Sciatica (Lumbosacral region)
0.776 0.224 0.000
I37 Pulmonary valve disorders
0.775 0.225 0.000
A80-A89 Viral infections of the central nervous system
0.774 0.226 0.000
D68 Other coagulation defects
0.774 0.226 0.000
O36.9 Maternal care for foetal problem, unspecified
0.774 0.226 0.000
M89.8 Other specified disorders of bone
0.773 0.227 0.000
M34 Systemic sclerosis
0.773 0.227 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.771 0.229 0.000
Y44 Agents primarily affecting blood constituents
0.771 0.229 0.000
O33 Maternal care for known or suspected disproportion
0.771 0.229 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.770 0.229 0.000
B35 Dermatophytosis
0.769 0.231 0.000
T63 Toxic effect of contact with venomous animals
0.769 0.231 0.000
M00 Pyogenic arthritis
0.769 0.231 0.000
O12.1 Gestational proteinuria
0.768 0.232 0.000
S62.5 Fracture of thumb
0.767 0.233 0.000
M81.4 Drug-induced osteoporosis
0.767 0.233 0.000
I47.0 Reentry ventricular arrhythmia
0.766 0.234 0.000
X78 Intentional self-harm by sharp object
0.766 0.234 0.000
S06 Intracranial injury
0.766 0.234 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.766 0.234 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.765 0.235 0.000
M21.26 Flexion deformity (Lower leg)
0.765 0.235 0.000
Q60-Q64 Congenital malformations of the urinary system
0.765 0.235 0.000
M91-M94 Chondropathies
0.764 0.236 0.000
T79.7 Traumatic subcutaneous emphysema
0.764 0.236 0.000
M30 Polyarteritis nodosa and related conditions
0.763 0.237 0.000
O45 Premature separation of placenta [abruptio placentae]
0.763 0.237 0.000
S05 Injury of eye and orbit
0.763 0.237 0.000
M21.24 Flexion deformity (Hand)
0.762 0.238 0.000
I05 Rheumatic mitral valve diseases
0.762 0.238 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.762 0.238 0.000
I08.9 Multiple valve disease, unspecified
0.762 0.238 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.761 0.238 0.000
U80 Agent resistant to penicillin and related antibiotics
0.761 0.239 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.760 0.240 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.760 0.240 0.000
M66 Spontaneous rupture of synovium and tendon
0.760 0.240 0.000
T45.2 Vitamins, not elsewhere classified
0.760 0.240 0.000
T17.2 Foreign body in pharynx
0.759 0.241 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.759 0.241 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.758 0.242 0.000
Y57 Other and unspecified drugs and medicaments
0.756 0.244 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.755 0.245 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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