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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3129923
log Bayes Factor = 214.888
Chromosome 6   position 32,333,195  (GRCh37) Explore rs3129923 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
L40 Psoriasis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.001 0.999
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
J45 Asthma
0.000 0.001 0.999
M07 Psoriatic and enteropathic arthropathies
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
M35 Other systemic involvement of connective tissue
0.000 0.003 0.997
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.003 0.997
M20-M25 Other joint disorders
0.000 0.003 0.997
G37 Other demyelinating diseases of central nervous system
0.996 0.004 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
J33.9 Nasal polyp, unspecified
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
E11.1 With ketoacidosis
0.000 0.009 0.991
E10.2 With renal complications
0.000 0.010 0.990
D64.9 Anaemia, unspecified
0.000 0.014 0.986
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.015 0.985
E83.1 Disorders of iron metabolism
0.982 0.018 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.019 0.981
E10.5 With peripheral circulatory complications
0.000 0.019 0.981
D64 Other anaemias
0.000 0.019 0.981
D60-D64 Aplastic and other anaemias
0.000 0.020 0.980
M06.3 Rheumatoid nodule
0.000 0.020 0.980
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.022 0.978
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.024 0.976
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.025 0.975
J30-J39 Other diseases of upper respiratory tract
0.000 0.025 0.975
L40.0 Psoriasis vulgaris
0.000 0.029 0.971
J33.8 Other polyp of sinus
0.000 0.032 0.968
M31 Other necrotising vasculopathies
0.000 0.033 0.967
J43 Emphysema
0.000 0.034 0.966
E10.0 With coma
0.000 0.036 0.964
K90 Intestinal malabsorption
0.000 0.039 0.961
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.047 0.953
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.051 0.949
Chapter XI Diseases of the digestive system
0.000 0.053 0.947
K90-K93 Other diseases of the digestive system
0.000 0.054 0.946
M06.4 Inflammatory polyarthropathy
0.000 0.058 0.942
E11.3 With ophthalmic complications
0.000 0.059 0.941
J95-J99 Other diseases of the respiratory system
0.000 0.060 0.940
K75 Other inflammatory liver diseases
0.000 0.064 0.936
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.064 0.936
K70-K77 Diseases of liver
0.000 0.064 0.936
M31.6 Other giant cell arteritis
0.000 0.066 0.934
K75.4 Autoimmune hepatitis
0.000 0.067 0.933
E27 Other disorders of adrenal gland
0.000 0.069 0.931
E20-E35 Disorders of other endocrine glands
0.000 0.071 0.929
E27.1 Primary adrenocortical insufficiency
0.000 0.075 0.925
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.076 0.924
H53-H54 Visual disturbances and blindness
0.000 0.078 0.922
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.080 0.920
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.083 0.917
E11.2 With renal complications
0.000 0.086 0.914
M45-M49 Spondylopathies
0.000 0.087 0.913
J95.0 Tracheostomy malfunction
0.000 0.088 0.912
L80 Vitiligo
0.000 0.089 0.911
K75.8 Other specified inflammatory liver diseases
0.000 0.090 0.910
E10.8 With unspecified complications
0.000 0.092 0.908
D50-D53 Nutritional anaemias
0.000 0.094 0.906
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.097 0.903
J86 Pyothorax
0.000 0.098 0.902
H54 Blindness and low vision
0.000 0.098 0.902
E06 Thyroiditis
0.000 0.100 0.900
M35.1 Other overlap syndromes
0.000 0.100 0.900
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.102 0.898
E10.6 With other specified complications
0.000 0.105 0.895
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.107 0.893
E83 Disorders of mineral metabolism
0.823 0.110 0.066
E70-E90 Metabolic disorders
0.001 0.116 0.883
J43.9 Emphysema, unspecified
0.000 0.118 0.882
E50-E64 Other nutritional deficiencies
0.000 0.119 0.881
E11.8 With unspecified complications
0.000 0.120 0.880
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.122 0.878
K73 Chronic hepatitis, not elsewhere classified
0.000 0.124 0.876
D50 Iron deficiency anaemia
0.000 0.127 0.873
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.128 0.872
H34 Retinal vascular occlusions
0.000 0.132 0.868
D50.9 Iron deficiency anaemia, unspecified
0.000 0.134 0.866
L10-L14 Bullous disorders
0.000 0.135 0.865
M34 Systemic sclerosis
0.000 0.143 0.856
E14.6 With other specified complications
0.000 0.144 0.856
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.146 0.854
E86 Volume depletion
0.000 0.147 0.853
G37.8 Other specified demyelinating diseases of central nervous system
0.852 0.148 0.000
M45 Ankylosing spondylitis
0.000 0.148 0.852
J43.2 Centrilobular emphysema
0.000 0.149 0.851
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.152 0.848
J46 Status asthmaticus
0.000 0.152 0.848
E14.1 With ketoacidosis
0.000 0.153 0.847
E53 Deficiency of other B group vitamins
0.000 0.153 0.847
H54.0 Blindness, both eyes
0.000 0.153 0.847
M65-M68 Disorders of synovium and tendon
0.000 0.156 0.844
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.159 0.841
M49 Spondylopathies in diseases classified elsewhere
0.000 0.159 0.841
H33 Retinal detachments and breaks
0.000 0.161 0.839
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.162 0.838
L40.1 Generalised pustular psoriasis
0.000 0.162 0.838
M06.34 Rheumatoid nodule (Hand)
0.000 0.164 0.836
L40.8 Other psoriasis
0.000 0.168 0.832
E53.8 Deficiency of other specified B group vitamins
0.000 0.169 0.831
H35 Other retinal disorders
0.000 0.169 0.831
M12 Other specific arthropathies
0.000 0.171 0.829
H54.7 Unspecified visual loss
0.000 0.171 0.829
J86.0 Pyothorax with fistula
0.000 0.173 0.827
J20-J22 Other acute lower respiratory infections
0.000 0.178 0.822
E14.8 With unspecified complications
0.000 0.179 0.821
J86.9 Pyothorax without fistula
0.000 0.181 0.819
E16.1 Other hypoglycaemia
0.000 0.181 0.819
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.184 0.816
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.186 0.814
K82 Other diseases of gallbladder
0.000 0.189 0.811
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.190 0.810
H33.3 Retinal breaks without detachment
0.000 0.191 0.809
D62 Acute posthaemorrhagic anaemia
0.000 0.192 0.808
E03.8 Other specified hypothyroidism
0.000 0.193 0.807
J39 Other diseases of upper respiratory tract
0.000 0.194 0.806
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.198 0.802
E14.2 Withrenal complications
0.000 0.199 0.801
E06.3 Autoimmune thyroiditis
0.000 0.200 0.800
K82.8 Other specified diseases of gallbladder
0.000 0.203 0.797
M24 Other specific joint derangements
0.000 0.205 0.795
H35.4 Peripheral retinal degeneration
0.000 0.206 0.794
H33.4 Traction detachment of retina
0.000 0.207 0.793
L90 Atrophic disorders of skin
0.000 0.208 0.792
E11.5 With peripheral circulatory complications
0.000 0.209 0.791
E88 Other metabolic disorders
0.000 0.209 0.790
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.211 0.789
J43.8 Other emphysema
0.000 0.212 0.788
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.214 0.786
K90.9 Intestinal malabsorption, unspecified
0.000 0.215 0.785
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.215 0.785
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.220 0.780
L92.0 Granuloma annulare
0.000 0.221 0.779
H35.8 Other specified retinal disorders
0.000 0.223 0.777
E78.2 Mixed hyperlipidaemia
0.000 0.226 0.774
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.229 0.771
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.229 0.771
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.231 0.769
M31.3 Wegener's granulomatosis
0.000 0.234 0.766
G36 Other acute disseminated demyelination
0.763 0.237 0.000
M35.7 Hypermobility syndrome
0.000 0.240 0.760
M06.0 Seronegative rheumatoid arthritis
0.000 0.240 0.760
M30 Polyarteritis nodosa and related conditions
0.000 0.243 0.757
L40.3 Pustulosis palmaris et plantaris
0.000 0.243 0.756
H54.2 Low vision, both eyes
0.000 0.245 0.755
E83.3 Disorders of phosphorus metabolism
0.741 0.246 0.014
M24.1 Other articular cartilage disorders
0.000 0.247 0.753
E78.4 Other hyperlipidaemia
0.000 0.249 0.751
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.251 0.749
M65 Synovitis and tenosynovitis
0.000 0.252 0.748
M31.7 Microscopic polyangiitis
0.000 0.252 0.748
K81 Cholecystitis
0.000 0.253 0.747
L90.0 Lichen sclerosus et atrophicus
0.000 0.253 0.747
M80-M85 Disorders of bone density and structure
0.000 0.255 0.745
J33.1 Polypoid sinus degeneration
0.000 0.256 0.744
K71 Toxic liver disease
0.000 0.257 0.743
E83.5 Disorders of calcium metabolism
0.740 0.259 0.001
L94 Other localised connective tissue disorders
0.000 0.260 0.740
J22 Unspecified acute lower respiratory infection
0.000 0.261 0.739
L12 Pemphigoid
0.000 0.264 0.736
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.266 0.734
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.269 0.731
H34.9 Retinal vascular occlusion, unspecified
0.000 0.271 0.729
E83.9 Disorder of mineral metabolism, unspecified
0.692 0.271 0.036
M35.2 Behcet's disease
0.000 0.272 0.728
M91-M94 Chondropathies
0.000 0.272 0.728
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.272 0.728
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.273 0.727
H54.1 Blindness, one eye, low vision, other eye
0.000 0.274 0.726
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.275 0.725
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.725 0.275 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.276 0.724
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.276 0.724
M80 Osteoporosis with pathological fracture
0.000 0.278 0.722
M31.8 Other specified necrotising vasculopathies
0.000 0.279 0.721
J39.8 Other specified diseases of upper respiratory tract
0.000 0.280 0.720
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.284 0.716
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.284 0.716
M07.2 Psoriatic spondylitis
0.000 0.284 0.716
M07.1 Arthritis mutilans
0.000 0.284 0.716
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.284 0.716
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.000 0.284 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.284 0.716
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.285 0.715
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.285 0.715
M35.5 Multifocal fibrosclerosis
0.000 0.285 0.715
H35.2 Other proliferative retinopathy
0.000 0.285 0.715
G37.5 Concentric sclerosis [Balo]
0.714 0.285 0.000
G37.4 Subacute necrotising myelitis
0.714 0.285 0.000
G37.2 Central pontine myelinolysis
0.714 0.285 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.285 0.000
G37.0 Diffuse sclerosis
0.714 0.285 0.000
L40.4 Guttate psoriasis
0.000 0.287 0.713
E11.4 With neurological complications
0.000 0.287 0.713
E28 Ovarian dysfunction
0.000 0.288 0.712
M34.1 CR(E)ST syndrome
0.000 0.290 0.710
H30 Chorioretinal inflammation
0.000 0.291 0.709
L13 Other bullous disorders
0.000 0.294 0.706
E27.8 Other specified disorders of adrenal gland
0.000 0.294 0.706
H43-H45 Disorders of vitreous body and globe
0.000 0.295 0.705
K81.9 Cholecystitis, unspecified
0.000 0.296 0.704
D64.4 Congenital dyserythropoietic anaemia
0.000 0.297 0.703
D64.3 Other sideroblastic anaemias
0.000 0.297 0.703
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.297 0.703
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.297 0.703
D64.0 Hereditary sideroblastic anaemia
0.000 0.297 0.703
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.297 0.703
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.297 0.703
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.298 0.702
M06.38 Rheumatoid nodule (Other)
0.000 0.298 0.702
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.298 0.702
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.298 0.702
M06.33 Rheumatoid nodule (Forearm)
0.000 0.298 0.702
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.298 0.702
E11.0 With coma
0.000 0.300 0.700
M05.2 Rheumatoid vasculitis
0.000 0.301 0.699
J44 Other chronic obstructive pulmonary disease
0.000 0.301 0.699
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.303 0.697
M31.1 Thrombotic microangiopathy
0.000 0.304 0.696
M06.1 Adult-onset Still's disease
0.000 0.306 0.694
M24.11 Other articular cartilage disorders (Shoulder region)
0.000 0.306 0.694
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.307 0.693
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.307 0.693
M31.2 Lethal midline granuloma
0.000 0.307 0.693
J43.1 Panlobular emphysema
0.000 0.307 0.693
J43.0 MacLeod's syndrome
0.000 0.307 0.693
K73.9 Chronic hepatitis, unspecified
0.000 0.307 0.693
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.308 0.692
H34.2 Other retinal artery occlusions
0.000 0.309 0.691
M86-M90 Other osteopathies
0.000 0.310 0.689
K90.3 Pancreatic steatorrhoea
0.000 0.311 0.689
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.311 0.689
K90.1 Tropical sprue
0.000 0.311 0.689
H20 Iridocyclitis
0.000 0.312 0.688
M12.3 Palindromic rheumatism
0.000 0.312 0.687
E06.5 Other chronic thyroiditis
0.000 0.313 0.687
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.316 0.684
E06.9 Thyroiditis, unspecified
0.000 0.316 0.684
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.317 0.683
L87 Transepidermal elimination disorders
0.000 0.317 0.683
L86 Keratoderma in diseases classified elsewhere
0.000 0.317 0.683
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.317 0.683
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.317 0.683
E14.5 With peripheral circulatory complications
0.000 0.318 0.682
E24 Cushing's syndrome
0.000 0.319 0.681
K50-K52 Noninfective enteritis and colitis
0.016 0.319 0.666
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.319 0.681
M07.6 Other enteropathic arthropathies
0.000 0.319 0.680
E78.6 Lipoprotein deficiency
0.000 0.320 0.680
K82.3 Fistula of gallbladder
0.000 0.320 0.680
H35.6 Retinal haemorrhage
0.000 0.320 0.680
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.322 0.678
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.322 0.678
L84 Corns and callosities
0.000 0.322 0.678
M34.8 Other forms of systemic sclerosis
0.000 0.322 0.678
K81.1 Chronic cholecystitis
0.000 0.323 0.677
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.323 0.677
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.324 0.676
D51 Vitamin B12 deficiency anaemia
0.000 0.324 0.676
H34.1 Central retinal artery occlusion
0.000 0.324 0.676
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.325 0.675
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.325 0.675
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.325 0.675
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.325 0.675
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.325 0.675
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.325 0.675
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.325 0.675
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.325 0.675
J96 Respiratory failure, not elsewhere classified
0.000 0.326 0.674
M24.7 Protrusio acetabuli
0.000 0.328 0.672
K75.2 Nonspecific reactive hepatitis
0.000 0.329 0.671
K75.1 Phlebitis of portal vein
0.000 0.329 0.671
K77 Liver disorders in diseases classified elsewhere
0.000 0.329 0.671
E70 Disorders of aromatic amino-acid metabolism
0.001 0.329 0.670
E88.2 Lipomatosis, not elsewhere classified
0.000 0.329 0.671
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.331 0.669
M32 Systemic lupus erythematosus
0.000 0.331 0.669
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.331 0.669
E89.0 Postprocedural hypothyroidism
0.000 0.331 0.669
J45.1 Nonallergic asthma
0.000 0.332 0.668
E27.5 Adrenomedullary hyperfunction
0.000 0.332 0.668
E27.0 Other adrenocortical overactivity
0.000 0.332 0.668
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.332 0.667
H20.0 Acute and subacute iridocyclitis
0.000 0.334 0.666
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.334 0.666
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.334 0.666
E32 Diseases of thymus
0.000 0.334 0.666
E31 Polyglandular dysfunction
0.000 0.334 0.666
E30 Disorders of puberty, not elsewhere classified
0.000 0.334 0.666
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.335 0.665
E14.4 With neurological complications
0.000 0.335 0.665
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.336 0.664
E07 Other disorders of thyroid
0.000 0.336 0.664
M14 Arthropathies in other diseases classified elsewhere
0.000 0.339 0.661
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.340 0.660
M00-M03 Infectious arthropathies
0.000 0.342 0.658
M06.8 Other specified rheumatoid arthritis
0.000 0.342 0.657
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.342 0.658
J95.5 Postprocedural subglottic stenosis
0.000 0.343 0.657
J95.4 Mendelson's syndrome
0.000 0.343 0.657
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.343 0.657
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.343 0.657
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.343 0.657
L10 Pemphigus
0.000 0.343 0.657
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.343 0.657
E40-E46 Malnutrition
0.000 0.345 0.655
E74 Other disorders of carbohydrate metabolism
0.001 0.346 0.653
E27.9 Disorder of adrenal gland, unspecified
0.000 0.347 0.653
H54.6 Unqualified visual loss, one eye
0.000 0.348 0.652
M15-M19 Arthrosis
0.000 0.349 0.651
E03.1 Congenital hypothyroidism without goitre
0.000 0.351 0.648
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.352 0.648
J39.0 Retropharyngeal and parapharyngeal abscess
0.000 0.352 0.648
H54.3 Unqualified visual loss, both eyes
0.000 0.353 0.647
E06.4 Drug-induced thyroiditis
0.000 0.354 0.646
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.354 0.646
E06.1 Subacute thyroiditis
0.000 0.354 0.646
E06.0 Acute thyroiditis
0.000 0.354 0.646
H54.5 Low vision, one eye
0.000 0.356 0.644
M18 Arthrosis of first carpometacarpal joint
0.000 0.356 0.644
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.356 0.644
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.356 0.644
E56 Other vitamin deficiencies
0.000 0.357 0.643
D53 Other nutritional anaemias
0.000 0.357 0.642
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.359 0.641
E83.8 Other disorders of mineral metabolism
0.590 0.362 0.048
E83.2 Disorders of zinc metabolism
0.590 0.362 0.048
E83.0 Disorders of copper metabolism
0.590 0.362 0.048
M94 Other disorders of cartilage
0.000 0.363 0.637
D50.1 Sideropenic dysphagia
0.000 0.365 0.635
L12.1 Cicatricial pemphigoid
0.000 0.366 0.634
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.366 0.634
E77 Disorders of glycoprotein metabolism
0.001 0.366 0.633
E76 Disorders of glycosaminoglycan metabolism
0.001 0.366 0.633
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.366 0.633
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.366 0.633
E25 Adrenogenital disorders
0.000 0.367 0.633
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.369 0.631
E63 Other nutritional deficiencies
0.000 0.369 0.631
E50 Vitamin A deficiency
0.000 0.369 0.631
E60 Dietary zinc deficiency
0.000 0.369 0.631
E59 Dietary selenium deficiency
0.000 0.369 0.631
E52 Niacin deficiency [pellagra]
0.000 0.369 0.631
M12.2 Villonodular synovitis (pigmented)
0.000 0.369 0.631
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.370 0.630
M31.9 Necrotising vasculopathy, unspecified
0.000 0.370 0.629
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.372 0.628
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.372 0.628
M34.9 Systemic sclerosis, unspecified
0.000 0.372 0.628
M60-M63 Disorders of muscles
0.000 0.373 0.627
J99.0 Rheumatoid lung disease
0.000 0.373 0.627
L94.2 Calcinosis cutis
0.000 0.377 0.623
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.377 0.623
H34.0 Transient retinal artery occlusion
0.000 0.378 0.622
L14 Bullous disorders in diseases classified elsewhere
0.000 0.380 0.620
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.380 0.620
J41 Simple and mucopurulent chronic bronchitis
0.000 0.380 0.619
E51 Thiamine deficiency
0.000 0.381 0.619
H10-H13 Disorders of conjunctiva
0.000 0.382 0.618
M34.0 Progressive systemic sclerosis
0.000 0.382 0.618
M82 Osteoporosis in diseases classified elsewhere
0.000 0.382 0.618
K50 Crohn's disease [regional enteritis]
0.000 0.384 0.616
E54 Ascorbic acid deficiency
0.000 0.384 0.616
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.386 0.614
M46 Other inflammatory spondylopathies
0.000 0.386 0.614
J37 Chronic laryngitis and laryngotracheitis
0.000 0.388 0.612
E28.3 Primary ovarian failure
0.000 0.389 0.611
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.389 0.611
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.389 0.611
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.389 0.611
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.389 0.611
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.389 0.611
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.389 0.611
E13 Other specified diabetes mellitus
0.000 0.392 0.608
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.392 0.608
E53.1 Pyridoxine deficiency
0.000 0.392 0.607
E53.0 Riboflavin deficiency
0.000 0.392 0.607
M35.8 Other specified systemic involvement of connective tissue
0.000 0.393 0.607
H31 Other disorders of choroid
0.000 0.393 0.607
K72 Hepatic failure, not elsewhere classified
0.000 0.394 0.606
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.395 0.605
E72 Other disorders of amino-acid metabolism
0.001 0.395 0.604
M86 Osteomyelitis
0.000 0.395 0.605
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.396 0.604
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.396 0.604
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.397 0.603
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.397 0.603
M49.4 Neuropathic spondylopathy
0.000 0.397 0.603
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.397 0.603
M49.2 Enterobacterial spondylitis
0.000 0.397 0.603
M49.1 Brucella spondylitis
0.000 0.397 0.603
M49.0 Tuberculosis of spine
0.000 0.397 0.603
M30.0 Polyarteritis nodosa
0.000 0.398 0.601
D55-D59 Haemolytic anaemias
0.000 0.399 0.601
E23 Hypofunction and other disorders of pituitary gland
0.000 0.399 0.601
M12.5 Traumatic arthropathy
0.000 0.399 0.601
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.401 0.599
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.402 0.598
G36.0 Neuromyelitis optica [Devic]
0.596 0.404 0.000
M24.6 Ankylosis of joint
0.000 0.404 0.596
M66 Spontaneous rupture of synovium and tendon
0.000 0.404 0.596
H35.1 Retinopathy of prematurity
0.000 0.404 0.596
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.404 0.595
M12.4 Intermittent hydrarthrosis
0.000 0.406 0.594
M12.1 Kaschin-Beck disease
0.000 0.406 0.594
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.406 0.594
L13.0 Dermatitis herpetiformis
0.000 0.407 0.593
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.409 0.591
K71.0 Toxic liver disease with cholestasis
0.000 0.413 0.587
L90.8 Other atrophic disorders of skin
0.000 0.413 0.587
J45.8 Mixed asthma
0.000 0.415 0.585
L12.9 Pemphigoid, unspecified
0.000 0.415 0.585

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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