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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9273339
log Bayes Factor = 437.281
Chromosome 6   position 32,623,430  (GRCh37) Explore rs9273339 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
D64.9 Anaemia, unspecified
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
N48 Other disorders of penis
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E14.3 With ophthalmic complications
0.000 0.000 1.000
D50-D53 Nutritional anaemias
0.000 0.000 1.000
Chapter II Neoplasms
0.000 0.000 1.000
E11.3 With ophthalmic complications
0.000 0.000 1.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.000 1.000
D00-D09 In situ neoplasms
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
N40-N51 Diseases of male genital organs
0.000 0.000 1.000
C15-C26 Malignant neoplasms of digestive organs
0.000 0.000 1.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.000 1.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.000 1.000
K70-K77 Diseases of liver
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
Chapter XI Diseases of the digestive system
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
K75 Other inflammatory liver diseases
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
K75.4 Autoimmune hepatitis
0.000 0.001 0.999
H36 Retinal disorders in diseases classified elsewhere
0.000 0.001 0.999
D50 Iron deficiency anaemia
0.000 0.001 0.999
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
M05 Seropositive rheumatoid arthritis
0.000 0.001 0.999
D64 Other anaemias
0.000 0.001 0.999
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.001 0.999
H30-H36 Disorders of choroid and retina
0.000 0.001 0.999
D50.9 Iron deficiency anaemia, unspecified
0.000 0.001 0.999
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.001 0.999
D60-D64 Aplastic and other anaemias
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
C21.0 Anus, unspecified
0.000 0.001 0.999
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.001 0.999
K90-K93 Other diseases of the digestive system
0.000 0.001 0.999
D07.1 Vulva
0.000 0.001 0.999
L90 Atrophic disorders of skin
0.000 0.002 0.998
Chapter XIV Diseases of the genitourinary system
0.000 0.002 0.998
L90.0 Lichen sclerosus et atrophicus
0.000 0.002 0.998
Chapter VII Diseases of the eye and adnexa
0.000 0.002 0.998
N00-N08 Glomerular diseases
0.000 0.002 0.998
J45 Asthma
0.000 0.002 0.998
E83.1 Disorders of iron metabolism
0.998 0.002 0.000
D06 Carcinoma in situ of cervix uteri
0.000 0.002 0.998
N48.6 Balanitis xerotica obliterans
0.000 0.003 0.997
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.004 0.996
D06.9 Cervix, unspecified
0.000 0.004 0.996
K51.4 Pseudopolyposis of colon
0.996 0.004 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.005 0.995
N48.1 Balanoposthitis
0.000 0.005 0.995
E10.5 With peripheral circulatory complications
0.000 0.005 0.995
J40-J47 Chronic lower respiratory diseases
0.000 0.006 0.994
E20-E35 Disorders of other endocrine glands
0.000 0.006 0.994
C21.1 Anal canal
0.000 0.006 0.994
Chapter X Diseases of the respiratory system
0.000 0.006 0.994
H43-H45 Disorders of vitreous body and globe
0.000 0.006 0.994
H43 Disorders of vitreous body
0.000 0.008 0.992
D51 Vitamin B12 deficiency anaemia
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.010 0.990
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.011 0.989
N05 Unspecified nephritic syndrome
0.000 0.011 0.989
E27 Other disorders of adrenal gland
0.000 0.012 0.988
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.014 0.986
K51.3 Ulcerative (chronic) rectosigmoiditis
0.986 0.014 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.015 0.985
L92.0 Granuloma annulare
0.000 0.015 0.985
H43.1 Vitreous haemorrhage
0.000 0.016 0.984
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.017 0.983
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.018 0.982
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.019 0.981
C20 Malignant neoplasm of rectum
0.000 0.020 0.980
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.020 0.980
E10.2 With renal complications
0.000 0.026 0.974
Chapter VI Diseases of the nervous system
0.000 0.026 0.974
J46 Status asthmaticus
0.000 0.030 0.970
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.031 0.969
N48.0 Leukoplakia of penis
0.000 0.032 0.968
K51.2 Ulcerative (chronic) proctitis
0.968 0.032 0.000
E10.0 With coma
0.000 0.035 0.965
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.035 0.965
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.035 0.965
J33.8 Other polyp of sinus
0.000 0.036 0.964
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.039 0.961
L40-L45 Papulosquamous disorders
0.000 0.042 0.958
E10.6 With other specified complications
0.000 0.044 0.956
H34 Retinal vascular occlusions
0.000 0.044 0.956
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.044 0.956
G63.2 Diabetic polyneuropathy
0.000 0.045 0.955
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.046 0.954
E11.5 With peripheral circulatory complications
0.000 0.047 0.953
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.047 0.953
E10.8 With unspecified complications
0.000 0.048 0.952
K51.8 Other ulcerative colitis
0.952 0.048 0.000
E07 Other disorders of thyroid
0.000 0.050 0.950
C09 Malignant neoplasm of tonsil
0.000 0.050 0.950
L80 Vitiligo
0.000 0.051 0.949
L40 Psoriasis
0.000 0.057 0.943
J95-J99 Other diseases of the respiratory system
0.000 0.061 0.939
L40.9 Psoriasis, unspecified
0.000 0.061 0.939
K51.5 Mucosal proctocolitis
0.938 0.062 0.000
N04 Nephrotic syndrome
0.000 0.064 0.936
M06.3 Rheumatoid nodule
0.000 0.068 0.932
K73 Chronic hepatitis, not elsewhere classified
0.000 0.068 0.932
H34.8 Other retinal vascular occlusions
0.000 0.068 0.932
H43.8 Other disorders of vitreous body
0.000 0.069 0.931
K72 Hepatic failure, not elsewhere classified
0.000 0.071 0.929
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.072 0.928
N49.2 Inflammatory disorders of scrotum
0.000 0.072 0.928
C09.9 Tonsil, unspecified
0.000 0.073 0.927
E07.9 Disorder of thyroid, unspecified
0.000 0.074 0.926
K90.9 Intestinal malabsorption, unspecified
0.000 0.075 0.925
G35-G37 Demyelinating diseases of the central nervous system
0.855 0.076 0.069
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.077 0.923
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.078 0.922
J30-J39 Other diseases of upper respiratory tract
0.000 0.080 0.920
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.080 0.920
C91.1 Chronic lymphocytic leukaemia
0.000 0.081 0.919
D50.8 Other iron deficiency anaemias
0.000 0.084 0.916
E11.2 With renal complications
0.000 0.084 0.916
K75.8 Other specified inflammatory liver diseases
0.000 0.085 0.915
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.086 0.914
E13 Other specified diabetes mellitus
0.000 0.092 0.908
E24 Cushing's syndrome
0.000 0.095 0.905
C91 Lymphoid leukaemia
0.000 0.095 0.905
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.096 0.904
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.096 0.904
N05.2 Diffuse membranous glomerulonephritis
0.000 0.097 0.903
K55-K64 Other diseases of intestines
0.000 0.097 0.903
K60 Fissure and fistula of anal and rectal regions
0.000 0.102 0.898
G56.0 Carpal tunnel syndrome
0.000 0.103 0.897
G56 Mononeuropathies of upper limb
0.000 0.104 0.896
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.105 0.895
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.107 0.893
M06.4 Inflammatory polyarthropathy
0.000 0.107 0.893
K60.2 Anal fissure, unspecified
0.000 0.108 0.892
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.109 0.891
E16.1 Other hypoglycaemia
0.000 0.112 0.888
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.113 0.887
E06 Thyroiditis
0.000 0.114 0.886
Chapter IX Diseases of the circulatory system
0.000 0.114 0.886
I20-I25 Ischaemic heart diseases
0.000 0.118 0.882
E50-E64 Other nutritional deficiencies
0.000 0.118 0.882
N05.1 Focal and segmental glomerular lesions
0.000 0.119 0.881
J45.0 Predominantly allergic asthma
0.000 0.121 0.879
L10-L14 Bullous disorders
0.000 0.122 0.878
H43.3 Other vitreous opacities
0.000 0.124 0.876
E11.6 With other specified complications
0.000 0.124 0.876
J86 Pyothorax
0.000 0.127 0.873
M45-M49 Spondylopathies
0.000 0.127 0.873
E14.8 With unspecified complications
0.000 0.131 0.869
K55 Vascular disorders of intestine
0.000 0.131 0.869
D07.4 Penis
0.000 0.134 0.866
N04.9 Unspecified
0.000 0.134 0.866
J98 Other respiratory disorders
0.000 0.134 0.866
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.135 0.865
E21.0 Primary hyperparathyroidism
0.000 0.136 0.864
N48.2 Other inflammatory disorders of penis
0.000 0.139 0.861
G70-G73 Diseases of myoneural junction and muscle
0.000 0.140 0.860
K55.2 Angiodysplasia of colon
0.000 0.141 0.859
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.142 0.858
N48.4 Impotence of organic origin
0.000 0.143 0.857
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.143 0.857
E53 Deficiency of other B group vitamins
0.000 0.143 0.857
E03.8 Other specified hypothyroidism
0.000 0.144 0.856
E14.1 With ketoacidosis
0.000 0.145 0.855
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.147 0.853
K72.0 Acute and subacute hepatic failure
0.000 0.148 0.852
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.150 0.850
E21.3 Hyperparathyroidism, unspecified
0.000 0.150 0.850
I24 Other acute ischaemic heart diseases
0.000 0.151 0.849
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.152 0.848
I25 Chronic ischaemic heart disease
0.000 0.152 0.848
E53.8 Deficiency of other specified B group vitamins
0.000 0.156 0.844
K51.0 Ulcerative (chronic) enterocolitis
0.840 0.160 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.161 0.839
N05.8 Other
0.000 0.163 0.837
E13.9 Without complications
0.000 0.165 0.835
I20 Angina pectoris
0.000 0.165 0.835
E06.3 Autoimmune thyroiditis
0.000 0.167 0.833
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.167 0.833
G00 Bacterial meningitis, not elsewhere classified
0.000 0.169 0.831
J86.0 Pyothorax with fistula
0.000 0.169 0.831
G61 Inflammatory polyneuropathy
0.000 0.170 0.830
E14.5 With peripheral circulatory complications
0.000 0.170 0.830
E14.4 With neurological complications
0.000 0.172 0.828
I74 Arterial embolism and thrombosis
0.000 0.172 0.828
G37 Other demyelinating diseases of central nervous system
0.805 0.174 0.020
M14 Arthropathies in other diseases classified elsewhere
0.000 0.175 0.825
E14.6 With other specified complications
0.000 0.176 0.824
C23 Malignant neoplasm of gallbladder
0.000 0.176 0.824
I25.5 Ischaemic cardiomyopathy
0.000 0.176 0.824
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.176 0.824
G59 Mononeuropathy in diseases classified elsewhere
0.000 0.177 0.823
N05.9 Unspecified
0.000 0.177 0.823
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.178 0.822
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.182 0.817
C04 Malignant neoplasm of floor of mouth
0.000 0.184 0.816
C22.9 Liver, unspecified
0.000 0.186 0.814
E27.2 Addisonian crisis
0.000 0.188 0.812
G60 Hereditary and idiopathic neuropathy
0.000 0.188 0.812
E11.0 With coma
0.000 0.188 0.812
K60.0 Acute anal fissure
0.000 0.189 0.811
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.189 0.811
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.190 0.810
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.191 0.809
I20.9 Angina pectoris, unspecified
0.000 0.192 0.808
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.196 0.804
M48 Other spondylopathies
0.000 0.198 0.802
I10-I15 Hypertensive diseases
0.000 0.198 0.802
C07 Malignant neoplasm of parotid gland
0.000 0.200 0.800
K60.1 Chronic anal fissure
0.000 0.203 0.797
E20 Hypoparathyroidism
0.000 0.204 0.796
D04 Carcinoma in situ of skin
0.000 0.204 0.796
E14.2 Withrenal complications
0.000 0.205 0.795
C22.1 Intrahepatic bile duct carcinoma
0.000 0.205 0.794
K74 Fibrosis and cirrhosis of liver
0.000 0.209 0.791
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.209 0.791
K57 Diverticular disease of intestine
0.000 0.212 0.788
C10 Malignant neoplasm of oropharynx
0.000 0.212 0.788
M12 Other specific arthropathies
0.000 0.217 0.783
C12 Malignant neoplasm of pyriform sinus
0.000 0.218 0.782
K57.3 Diverticular disease of large intestine without perforation or abscess
0.000 0.219 0.781
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.220 0.780
G51 Facial nerve disorders
0.000 0.221 0.779
D06.0 Endocervix
0.000 0.222 0.778
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.222 0.778
G72 Other myopathies
0.000 0.224 0.776
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.226 0.774
J44 Other chronic obstructive pulmonary disease
0.000 0.227 0.773
E24.0 Pituitary-dependent Cushing's disease
0.000 0.227 0.773
G37.9 Demyelinating disease of central nervous system, unspecified
0.770 0.228 0.003
G00.1 Pneumococcal meningitis
0.000 0.228 0.772
L13 Other bullous disorders
0.000 0.229 0.771
I74.8 Embolism and thrombosis of other arteries
0.000 0.229 0.771
I77 Other disorders of arteries and arterioles
0.000 0.231 0.769
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.231 0.769
C60-C63 Malignant neoplasms of male genital organs
0.000 0.231 0.769
I20.0 Unstable angina
0.000 0.232 0.768
I74.5 Embolism and thrombosis of iliac artery
0.000 0.232 0.768
K72.9 Hepatic failure, unspecified
0.000 0.233 0.767
I10 Essential (primary) hypertension
0.000 0.234 0.766
C11 Malignant neoplasm of nasopharynx
0.000 0.238 0.762
M45 Ankylosing spondylitis
0.000 0.239 0.761
L94 Other localised connective tissue disorders
0.000 0.239 0.761
E05.8 Other thyrotoxicosis
0.000 0.240 0.760
H35 Other retinal disorders
0.000 0.241 0.759
G59.0 Diabetic mononeuropathy
0.000 0.242 0.758
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.242 0.758
N48.9 Disorder of penis, unspecified
0.000 0.243 0.757
N48.5 Ulcer of penis
0.000 0.243 0.757
M48.0 Spinal stenosis
0.000 0.244 0.756
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.245 0.755
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.245 0.755
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.247 0.753
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.248 0.752
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.248 0.752
M10 Gout
0.000 0.249 0.751
E24.9 Cushing's syndrome, unspecified
0.000 0.249 0.751
M06.8 Other specified rheumatoid arthritis
0.000 0.249 0.751
N04.1 Focal and segmental glomerular lesions
0.000 0.250 0.750
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.250 0.750
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.251 0.749
J45.1 Nonallergic asthma
0.000 0.251 0.749
C13 Malignant neoplasm of hypopharynx
0.000 0.254 0.746
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.254 0.746
M14.6 Neuropathic arthropathy
0.000 0.257 0.743
G70 Myasthenia gravis and other myoneural disorders
0.000 0.260 0.740
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.261 0.739
L40.1 Generalised pustular psoriasis
0.000 0.262 0.737
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.265 0.735
G61.0 Guillain-Barre syndrome
0.000 0.266 0.734
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.266 0.734
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.268 0.732
I25.2 Old myocardial infarction
0.000 0.270 0.730
L12 Pemphigoid
0.000 0.271 0.729
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.271 0.729
K73.9 Chronic hepatitis, unspecified
0.000 0.272 0.728
L40.0 Psoriasis vulgaris
0.000 0.272 0.728
K55.8 Other vascular disorders of intestine
0.000 0.273 0.727
M05.2 Rheumatoid vasculitis
0.000 0.276 0.724
J98.4 Other disorders of lung
0.000 0.276 0.724
C91.9 Lymphoid leukaemia, unspecified
0.000 0.278 0.722
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.278 0.722
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.278 0.722
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.279 0.721
M49 Spondylopathies in diseases classified elsewhere
0.000 0.279 0.721
H30 Chorioretinal inflammation
0.000 0.280 0.720
C01 Malignant neoplasm of base of tongue
0.000 0.280 0.720
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.280 0.720
G72.0 Drug-induced myopathy
0.000 0.282 0.718
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.282 0.718
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
C21.2 Cloacogenic zone
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.283 0.717
L87 Transepidermal elimination disorders
0.000 0.283 0.717
L86 Keratoderma in diseases classified elsewhere
0.000 0.283 0.717
K77 Liver disorders in diseases classified elsewhere
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
K75.2 Nonspecific reactive hepatitis
0.000 0.283 0.717
K75.1 Phlebitis of portal vein
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.283 0.717
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.283 0.717
K90.1 Tropical sprue
0.000 0.283 0.717
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.283 0.716
D50.1 Sideropenic dysphagia
0.000 0.283 0.716
M05.8 Other seropositive rheumatoid arthritis
0.000 0.284 0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.284 0.716
M05.1 Rheumatoid lung disease
0.000 0.284 0.716
M05.0 Felty's syndrome
0.000 0.284 0.716
D64.4 Congenital dyserythropoietic anaemia
0.000 0.284 0.716
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.284 0.716
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.284 0.716
D64.0 Hereditary sideroblastic anaemia
0.000 0.284 0.716
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.284 0.716
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.284 0.716
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.284 0.716
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.284 0.716
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.284 0.716
D07.6 Other and unspecified male genital organs
0.000 0.284 0.716
D07.3 Other and unspecified female genital organs
0.000 0.284 0.716
D07.0 Endometrium
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.716
L90.9 Atrophic disorder of skin, unspecified
0.000 0.284 0.716
L90.6 Striae atrophicae
0.000 0.284 0.716
L90.4 Acrodermatitis chronica atrophicans
0.000 0.284 0.716
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.284 0.716
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.284 0.716
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.284 0.716
J98.6 Disorders of diaphragm
0.000 0.284 0.716
E21.2 Other hyperparathyroidism
0.000 0.284 0.716
N07 Hereditary nephropathy, not elsewhere classified
0.000 0.284 0.715
N06 Isolated proteinuria with specified morphological lesion
0.000 0.284 0.715
N01 Rapidly progressive nephritic syndrome
0.000 0.284 0.715
N00 Acute nephritic syndrome
0.000 0.284 0.715
D06.7 Other parts of cervix
0.000 0.285 0.715
D06.1 Exocervix
0.000 0.285 0.715
C17 Malignant neoplasm of small intestine
0.000 0.285 0.715
C62 Malignant neoplasm of testis
0.000 0.285 0.715
D01.3 Anus and anal canal
0.000 0.286 0.714
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.286 0.714
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.286 0.714
C91.0 Acute lymphoblastic leukaemia
0.000 0.287 0.713
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.287 0.713
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.287 0.713
E32 Diseases of thymus
0.000 0.287 0.713
E31 Polyglandular dysfunction
0.000 0.287 0.713
E30 Disorders of puberty, not elsewhere classified
0.000 0.287 0.713
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.287 0.712
M06.34 Rheumatoid nodule (Hand)
0.000 0.289 0.711
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.290 0.710
D51.2 Transcobalamin II deficiency
0.000 0.290 0.710
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.290 0.710
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.291 0.709
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.291 0.709
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.291 0.709
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.291 0.709
N05.6 Dense deposit disease
0.000 0.291 0.709
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.291 0.709
N05.0 Minor glomerular abnormality
0.000 0.291 0.709
E27.5 Adrenomedullary hyperfunction
0.000 0.291 0.709
E27.0 Other adrenocortical overactivity
0.000 0.291 0.709
N44 Torsion of testis
0.000 0.292 0.708
M48.09 Spinal stenosis (Site unspecified)
0.000 0.293 0.707
M47 Spondylosis
0.000 0.296 0.704
E11.8 With unspecified complications
0.000 0.296 0.704
H31 Other disorders of choroid
0.000 0.296 0.703
E21.4 Other specified disorders of parathyroid gland
0.000 0.297 0.703
N04.2 Diffuse membranous glomerulonephritis
0.000 0.298 0.702
E24.2 Drug-induced Cushing's syndrome
0.000 0.298 0.702
L40.4 Guttate psoriasis
0.000 0.299 0.701
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.299 0.701
H35.2 Other proliferative retinopathy
0.000 0.300 0.700
D04.9 Skin, unspecified
0.000 0.300 0.700
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.300 0.699
K71 Toxic liver disease
0.000 0.303 0.697
C04.9 Floor of mouth, unspecified
0.000 0.303 0.697
H43.0 Vitreous prolapse
0.000 0.303 0.696
D01.0 Colon
0.000 0.304 0.696
G64 Other disorders of peripheral nervous system
0.000 0.305 0.695
H25-H28 Disorders of lens
0.000 0.305 0.695
D53 Other nutritional anaemias
0.000 0.306 0.694
L13.0 Dermatitis herpetiformis
0.000 0.306 0.694
I77.6 Arteritis, unspecified
0.000 0.308 0.692
H34.2 Other retinal artery occlusions
0.000 0.308 0.692
C95 Leukaemia of unspecified cell type
0.000 0.311 0.689
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.311 0.689
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.311 0.689
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.311 0.689
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.311 0.689
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.311 0.689
G63.1 Polyneuropathy in neoplastic disease
0.000 0.311 0.689
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.311 0.689
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.312 0.688
H34.9 Retinal vascular occlusion, unspecified
0.000 0.312 0.688
L44 Other papulosquamous disorders
0.000 0.313 0.687
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.313 0.687
D07.2 Vagina
0.000 0.313 0.687
D04.7 Skin of lower limb, including hip
0.000 0.313 0.687
H43.2 Crystalline deposits in vitreous body
0.000 0.314 0.686
H34.0 Transient retinal artery occlusion
0.000 0.314 0.686
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.314 0.686
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.314 0.686
M06.1 Adult-onset Still's disease
0.000 0.316 0.684
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.317 0.683
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.318 0.682
E07.1 Dyshormogenetic goitre
0.000 0.319 0.681
E07.0 Hypersecretion of calcitonin
0.000 0.319 0.681
C09.8 Overlapping lesion of tonsil
0.000 0.319 0.681
C09.1 Tonsillar pillar (anterior) (posterior)
0.000 0.319 0.681
C09.0 Tonsillar fossa
0.000 0.320 0.679
M11 Other crystal arthropathies
0.000 0.320 0.679
K51.1 Ulcerative (chronic) ileocolitis
0.679 0.321 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.321 0.679
L40.3 Pustulosis palmaris et plantaris
0.000 0.323 0.676
L40.2 Acrodermatitis continua
0.000 0.323 0.676
E13.3 With ophthalmic complications
0.000 0.324 0.676
G60.0 Hereditary motor and sensory neuropathy
0.000 0.324 0.676
J45.8 Mixed asthma
0.000 0.324 0.675
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.325 0.675
G51.9 Disorder of facial nerve, unspecified
0.000 0.326 0.674
E25 Adrenogenital disorders
0.000 0.326 0.674
J96 Respiratory failure, not elsewhere classified
0.000 0.327 0.673
G00.9 Bacterial meningitis, unspecified
0.000 0.327 0.673
E40-E46 Malnutrition
0.000 0.327 0.672
N04.8 Other
0.000 0.328 0.671
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.328 0.671
N04.6 Dense deposit disease
0.000 0.328 0.671
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.328 0.671
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.328 0.671
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.328 0.671
N04.0 Minor glomerular abnormality
0.000 0.328 0.671
C62.9 Testis, unspecified
0.000 0.330 0.670
I25.1 Atherosclerotic heart disease
0.000 0.330 0.670
J86.9 Pyothorax without fistula
0.000 0.330 0.670
M47.9 Spondylosis, unspecified
0.000 0.332 0.668
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.332 0.668
M06.38 Rheumatoid nodule (Other)
0.000 0.332 0.668
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.332 0.668
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.332 0.668
M06.33 Rheumatoid nodule (Forearm)
0.000 0.332 0.668
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.332 0.668
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.332 0.668
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.332 0.668
M48.8 Other specified spondylopathies
0.000 0.334 0.666
L40.8 Other psoriasis
0.000 0.337 0.662
G56.4 Causalgia
0.000 0.338 0.662

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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