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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs532965
log Bayes Factor = 522.853
Chromosome 6   position 32,577,973  (GRCh37) Explore rs532965 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
1.000 0.000 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
1.000 0.000 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
1.000 0.000 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
J33.9 Nasal polyp, unspecified
1.000 0.000 0.000
J33.0 Polyp of nasal cavity
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M35.3 Polymyalgia rheumatica
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
J33 Nasal polyp
1.000 0.000 0.000
K51 Ulcerative colitis
0.000 0.000 1.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
M06.3 Rheumatoid nodule
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
J45 Asthma
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
1.000 0.000 0.000
M31 Other necrotising vasculopathies
1.000 0.000 0.000
J32 Chronic sinusitis
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
M31.6 Other giant cell arteritis
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E11.3 With ophthalmic complications
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
J32.9 Chronic sinusitis, unspecified
1.000 0.000 0.000
H00 Hordeolum and chalazion
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.999 0.001 0.000
M06.34 Rheumatoid nodule (Hand)
0.999 0.001 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
E10.5 With peripheral circulatory complications
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.999 0.001 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.999 0.001 0.000
E14.9 Without complications
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
M65-M68 Disorders of synovium and tendon
0.999 0.001 0.000
J20-J22 Other acute lower respiratory infections
0.998 0.002 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.998 0.002 0.000
J33.8 Other polyp of sinus
0.998 0.002 0.000
M06.0 Seronegative rheumatoid arthritis
0.998 0.002 0.000
M65 Synovitis and tenosynovitis
0.998 0.002 0.000
M20 Acquired deformities of fingers and toes
0.998 0.002 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.997 0.003 0.000
J22 Unspecified acute lower respiratory infection
0.996 0.004 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.996 0.004 0.000
J95-J99 Other diseases of the respiratory system
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.995 0.005 0.000
E14.3 With ophthalmic complications
0.994 0.006 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.993 0.007 0.000
M25.4 Effusion of joint
0.993 0.007 0.000
M25 Other joint disorders, not elsewhere classified
0.993 0.007 0.000
H00.1 Chalazion
0.993 0.007 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.991 0.009 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.990 0.010 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.989 0.011 0.000
H20 Iridocyclitis
0.989 0.011 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.989 0.011 0.000
M25.46 Effusion of joint (Lower leg)
0.988 0.012 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.012 0.988
L97 Ulcer of lower limb, not elsewhere classified
0.988 0.012 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.988 0.012 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.987 0.013 0.000
K52 Other non-infective gastro-enteritis and colitis
0.000 0.013 0.987
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.014 0.986
L05 Pilonidal cyst
0.985 0.015 0.000
E11.1 With ketoacidosis
0.985 0.015 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.981 0.019 0.000
J46 Status asthmaticus
0.981 0.019 0.000
L05.0 Pilonidal cyst with abscess
0.981 0.019 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.980 0.020 0.000
J44 Other chronic obstructive pulmonary disease
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
J47 Bronchiectasis
0.978 0.022 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.974 0.026 0.000
E10.8 With unspecified complications
0.972 0.028 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.029 0.971
K51.4 Pseudopolyposis of colon
0.000 0.031 0.969
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.969 0.031 0.000
H04 Disorders of lachrymal system
0.967 0.033 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.963 0.037 0.000
E10.6 With other specified complications
0.963 0.037 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.960 0.040 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.958 0.042 0.000
L89 Decubitus ulcer
0.956 0.044 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.954 0.046 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.953 0.047 0.000
E06 Thyroiditis
0.953 0.047 0.000
H16 Keratitis
0.949 0.051 0.000
M25.40 Effusion of joint (Multiple sites)
0.946 0.054 0.000
M06.4 Inflammatory polyarthropathy
0.945 0.055 0.000
M86-M90 Other osteopathies
0.944 0.056 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.941 0.059 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.060 0.940
E10.2 With renal complications
0.940 0.060 0.000
L89.1 Stage II decubitus ulcer
0.939 0.061 0.000
J45.0 Predominantly allergic asthma
0.938 0.062 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.935 0.065 0.000
E10.0 With coma
0.934 0.066 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.932 0.068 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.927 0.073 0.000
J99.0 Rheumatoid lung disease
0.926 0.074 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.925 0.075 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.923 0.077 0.000
E06.3 Autoimmune thyroiditis
0.923 0.077 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.922 0.078 0.000
K52.3 Indeterminate colitis
0.000 0.079 0.921
L80 Vitiligo
0.921 0.079 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.921 0.079 0.000
M12 Other specific arthropathies
0.920 0.080 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.920 0.080 0.000
M35.1 Other overlap syndromes
0.918 0.082 0.000
H20.9 Iridocyclitis, unspecified
0.918 0.082 0.000
E11.5 With peripheral circulatory complications
0.917 0.083 0.000
G63.2 Diabetic polyneuropathy
0.915 0.085 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.914 0.086 0.000
J32.2 Chronic ethmoidal sinusitis
0.913 0.087 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.912 0.088 0.000
H04.1 Other disorders of lachrymal gland
0.912 0.088 0.000
Chapter VI Diseases of the nervous system
0.911 0.088 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.911 0.089 0.000
M20.4 Other hammer toe(s) (acquired)
0.911 0.089 0.000
H01 Other inflammation of eyelid
0.907 0.093 0.000
W00-W19 Falls
0.903 0.097 0.000
E14.6 With other specified complications
0.901 0.099 0.000
J98 Other respiratory disorders
0.901 0.099 0.000
J00-J06 Acute upper respiratory infections
0.901 0.099 0.000
K51.8 Other ulcerative colitis
0.000 0.100 0.900
M20.5 Other deformities of toe(s) (acquired)
0.897 0.103 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.896 0.104 0.000
H20.0 Acute and subacute iridocyclitis
0.894 0.106 0.000
Q28 Other congenital malformations of circulatory system
0.894 0.106 0.000
H53-H54 Visual disturbances and blindness
0.891 0.109 0.000
M14 Arthropathies in other diseases classified elsewhere
0.889 0.111 0.000
M20.1 Hallux valgus (acquired)
0.889 0.111 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.884 0.116 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.881 0.119 0.000
M05.8 Other seropositive rheumatoid arthritis
0.880 0.120 0.000
V20-V29 Motorcycle rider injured in transport accident
0.879 0.121 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.878 0.122 0.000
Q66 Congenital deformities of feet
0.878 0.122 0.000
E50-E64 Other nutritional deficiencies
0.876 0.124 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.872 0.128 0.000
M25.47 Effusion of joint (Ankle and foot)
0.870 0.130 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.869 0.131 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.864 0.136 0.000
H20.8 Other iridocyclitis
0.863 0.137 0.000
J95.0 Tracheostomy malfunction
0.863 0.137 0.000
M89 Other disorders of bone
0.857 0.143 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.857 0.143 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.855 0.145 0.000
M30 Polyarteritis nodosa and related conditions
0.855 0.145 0.000
J35 Chronic diseases of tonsils and adenoids
0.854 0.146 0.000
J84 Other interstitial pulmonary diseases
0.852 0.148 0.000
J32.0 Chronic maxillary sinusitis
0.851 0.149 0.000
Y00-Y09 Assault
0.851 0.149 0.000
M21 Other acquired deformities of limbs
0.851 0.149 0.000
W15 Fall from cliff
0.851 0.149 0.000
H31 Other disorders of choroid
0.850 0.150 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.848 0.152 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.848 0.152 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.848 0.152 0.000
Q80-Q89 Other congenital malformations
0.848 0.152 0.000
M05.1 Rheumatoid lung disease
0.846 0.154 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.154 0.846
K51.5 Mucosal proctocolitis
0.000 0.156 0.844
H15 Disorders of sclera
0.842 0.158 0.000
L05.9 Pilonidal cyst without abscess
0.840 0.160 0.000
M48 Other spondylopathies
0.839 0.161 0.000
J98.1 Pulmonary collapse
0.838 0.162 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.838 0.162 0.000
M06.8 Other specified rheumatoid arthritis
0.837 0.162 0.000
M12.3 Palindromic rheumatism
0.836 0.164 0.000
M86 Osteomyelitis
0.834 0.166 0.000
M60-M63 Disorders of muscles
0.833 0.167 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.833 0.167 0.000
M31.7 Microscopic polyangiitis
0.832 0.168 0.000
E10.7 With multiple complications
0.832 0.168 0.000
M66 Spontaneous rupture of synovium and tendon
0.832 0.168 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.832 0.168 0.000
Y52 Agents primarily affecting the cardiovascular system
0.830 0.170 0.000
M25.3 Other instability of joint
0.830 0.170 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.828 0.172 0.000
J32.4 Chronic pansinusitis
0.828 0.172 0.000
H17 Corneal scars and opacities
0.828 0.172 0.000
L90 Atrophic disorders of skin
0.826 0.174 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.825 0.175 0.000
M00-M03 Infectious arthropathies
0.822 0.177 0.000
H16.0 Corneal ulcer
0.822 0.178 0.000
H01.0 Blepharitis
0.821 0.179 0.000
H16.8 Other keratitis
0.819 0.181 0.000
Y40 Systemic antibiotics
0.818 0.182 0.000
J32.1 Chronic frontal sinusitis
0.815 0.185 0.000
J20 Acute bronchitis
0.814 0.186 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.814 0.186 0.000
Y48 Anaesthetics and therapeutic gases
0.813 0.187 0.000
M31.3 Wegener's granulomatosis
0.812 0.188 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.811 0.189 0.000
L91 Hypertrophic disorders of skin
0.809 0.191 0.000
Q66.8 Other congenital deformities of feet
0.809 0.191 0.000
H20.1 Chronic iridocyclitis
0.807 0.193 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.807 0.193 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.806 0.194 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.196 0.804
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.802 0.198 0.000
J42 Unspecified chronic bronchitis
0.801 0.199 0.000
M34 Systemic sclerosis
0.801 0.199 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.801 0.199 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.801 0.199 0.000
M65.1 Other infective (teno)synovitis
0.799 0.201 0.000
W15.8 Other specified place
0.798 0.202 0.000
M08 Juvenile arthritis
0.797 0.203 0.000
Q27 Other congenital malformations of peripheral vascular system
0.797 0.203 0.000
J33.1 Polypoid sinus degeneration
0.797 0.203 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.797 0.203 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.796 0.204 0.000
W75-W84 Other accidental threats to breathing
0.796 0.204 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.795 0.205 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.793 0.207 0.000
H16.4 Corneal neovascularisation
0.793 0.207 0.000
V10-V19 Pedal cyclist injured in transport accident
0.790 0.210 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.789 0.211 0.000
L90.0 Lichen sclerosus et atrophicus
0.789 0.211 0.000
M20.0 Deformity of finger(s)
0.788 0.212 0.000
Q24 Other congenital malformations of heart
0.788 0.212 0.000
H43-H45 Disorders of vitreous body and globe
0.787 0.213 0.000
J21 Acute bronchiolitis
0.786 0.214 0.000
M89.0 Algoneurodystrophy
0.785 0.215 0.000
E07 Other disorders of thyroid
0.785 0.215 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.785 0.215 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.784 0.216 0.000
Q35-Q37 Cleft lip and cleft palate
0.780 0.220 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.780 0.220 0.000
Y04 Assault by bodily force
0.779 0.221 0.000
J98.4 Other disorders of lung
0.778 0.222 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.778 0.222 0.000
M49 Spondylopathies in diseases classified elsewhere
0.774 0.226 0.000
J01 Acute sinusitis
0.774 0.226 0.000
M65.8 Other synovitis and tenosynovitis
0.771 0.229 0.000
G90-G99 Other disorders of the nervous system
0.771 0.229 0.000
Q78 Other osteochondrodysplasias
0.770 0.230 0.000
M25.8 Other specified joint disorders
0.770 0.230 0.000
H05 Disorders of orbit
0.769 0.231 0.000
J80 Adult respiratory distress syndrome
0.768 0.232 0.000
M25.43 Effusion of joint (Forearm)
0.767 0.233 0.000
X50-X57 Overexertion, travel and privation
0.766 0.234 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.765 0.235 0.000
M14.6 Neuropathic arthropathy
0.763 0.237 0.000
E61 Deficiency of other nutrient elements
0.762 0.238 0.000
W06 Fall involving bed
0.761 0.239 0.000
E53 Deficiency of other B group vitamins
0.761 0.239 0.000
W50-W64 Exposure to animate mechanical forces
0.759 0.241 0.000
M31.8 Other specified necrotising vasculopathies
0.758 0.242 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.243 0.757
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.756 0.244 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.755 0.244 0.000
J35.1 Hypertrophy of tonsils
0.755 0.245 0.000
V80-V89 Other land transport accidents
0.754 0.246 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.754 0.246 0.000
H53 Visual disturbances
0.754 0.246 0.000
M91-M94 Chondropathies
0.753 0.246 0.000
H31.0 Chorioretinal scars
0.753 0.247 0.000
E14.1 With ketoacidosis
0.753 0.247 0.000
H55-H59 Other disorders of eye and adnexa
0.753 0.247 0.000
Y58 Bacterial vaccines
0.752 0.248 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.752 0.248 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.752 0.248 0.000
H21 Other disorders of iris and ciliary body
0.750 0.250 0.000
H01.8 Other specified inflammation of eyelid
0.750 0.250 0.000
M89.8 Other specified disorders of bone
0.750 0.250 0.000
Q83 Congenital malformations of breast
0.749 0.251 0.000
M25.36 Other instability of joint (Lower leg)
0.749 0.251 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.314 0.252 0.434
V95-V97 Air and space transport accidents
0.747 0.253 0.000
H54 Blindness and low vision
0.747 0.253 0.000
E11.6 With other specified complications
0.747 0.253 0.000
Y42.1 Thyroid hormones and substitutes
0.747 0.253 0.000
H30 Chorioretinal inflammation
0.745 0.255 0.000
W14 Fall from tree
0.745 0.255 0.000
E11.4 With neurological complications
0.744 0.256 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.744 0.256 0.000
M66.2 Spontaneous rupture of extensor tendons
0.742 0.258 0.000
E16.1 Other hypoglycaemia
0.742 0.258 0.000
M25.9 Joint disorder, unspecified
0.742 0.258 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.741 0.259 0.000
G61 Inflammatory polyneuropathy
0.741 0.259 0.000
M12.2 Villonodular synovitis (pigmented)
0.740 0.259 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.740 0.260 0.000
W05 Fall involving wheelchair
0.738 0.262 0.000
M35.8 Other specified systemic involvement of connective tissue
0.737 0.263 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.736 0.264 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.736 0.264 0.000
E11.0 With coma
0.735 0.265 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.735 0.265 0.000
L89.2 Stage III decubitus ulcer
0.735 0.265 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.733 0.267 0.000
E14.5 With peripheral circulatory complications
0.732 0.267 0.000
G95 Other diseases of spinal cord
0.732 0.268 0.000
M14.2 Diabetic arthropathy
0.732 0.268 0.000
Y42.5 Other oestrogens and progestogens
0.732 0.268 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.731 0.269 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.731 0.269 0.000
Q21 Congenital malformations of cardiac septa
0.730 0.270 0.000
M86.9 Osteomyelitis, unspecified
0.728 0.272 0.000
J32.3 Chronic sphenoidal sinusitis
0.728 0.272 0.000
E03.8 Other specified hypothyroidism
0.727 0.273 0.000
L10-L14 Bullous disorders
0.727 0.273 0.000
E14.2 Withrenal complications
0.726 0.274 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.726 0.274 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.725 0.275 0.000
H16.3 Interstitial and deep keratitis
0.723 0.277 0.000
Q25 Congenital malformations of great arteries
0.722 0.278 0.000
M20.3 Other deformity of hallux (acquired)
0.721 0.279 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.720 0.280 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.720 0.280 0.000
X00-X09 Exposure to smoke, fire and flames
0.720 0.280 0.000
L94 Other localised connective tissue disorders
0.718 0.281 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.718 0.281 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.718 0.282 0.000
M12.39 Palindromic rheumatism (Site unspecified)
0.718 0.282 0.000
J95.8 Other postprocedural respiratory disorders
0.718 0.282 0.000
J85 Abscess of lung and mediastinum
0.718 0.282 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.717 0.283 0.000
M06.38 Rheumatoid nodule (Other)
0.717 0.283 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.717 0.283 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.717 0.283 0.000
M06.33 Rheumatoid nodule (Forearm)
0.717 0.283 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.717 0.283 0.000
J45.8 Mixed asthma
0.717 0.283 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.717 0.283 0.000
M05.2 Rheumatoid vasculitis
0.717 0.283 0.000
M05.0 Felty's syndrome
0.717 0.283 0.000
M31.2 Lethal midline granuloma
0.717 0.283 0.000
M31.1 Thrombotic microangiopathy
0.717 0.283 0.000
M31.0 Hypersensitivity angiitis
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.717 0.283 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.283 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.283 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.716 0.283 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.283 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.283 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.283 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.716 0.284 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.715 0.284 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.715 0.284 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.715 0.284 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.715 0.284 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.715 0.284 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.715 0.284 0.000
M65.2 Calcific tendinitis
0.715 0.284 0.000
M65.0 Abscess of tendon sheath
0.715 0.284 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.715 0.285 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.715 0.285 0.000
J96 Respiratory failure, not elsewhere classified
0.714 0.286 0.000
E11.8 With unspecified complications
0.712 0.288 0.000
E14.4 With neurological complications
0.712 0.288 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.712 0.288 0.000
M25.49 Effusion of joint (Site unspecified)
0.712 0.288 0.000
M25.48 Effusion of joint (Other)
0.712 0.288 0.000
M25.41 Effusion of joint (Shoulder region)
0.712 0.288 0.000
M25.2 Flail joint
0.712 0.288 0.000
M25.1 Fistula of joint
0.712 0.288 0.000
J45.1 Nonallergic asthma
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.710 0.290 0.000
L87 Transepidermal elimination disorders
0.710 0.290 0.000
L86 Keratoderma in diseases classified elsewhere
0.710 0.290 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.709 0.291 0.000
H20.2 Lens-induced iridocyclitis
0.709 0.291 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.709 0.291 0.000
L00 Staphylococcal scalded skin syndrome
0.708 0.292 0.000
W10 Fall on and from stairs and steps
0.707 0.293 0.000
M35.2 Behcet's disease
0.706 0.294 0.000
Q66.0 Talipes equinovarus
0.705 0.295 0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.705 0.295 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.705 0.295 0.000
H17.9 Corneal scar and opacity, unspecified
0.705 0.295 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.705 0.295 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.704 0.296 0.000
Y54.3 Benzothiadiazine derivatives
0.704 0.296 0.000
M31.9 Necrotising vasculopathy, unspecified
0.704 0.296 0.000
M90 Osteopathies in diseases classified elsewhere
0.704 0.296 0.000
H15.1 Episcleritis
0.703 0.297 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.297 0.000
L04 Acute lymphadenitis
0.703 0.297 0.000
Y04.8 Other specified place
0.703 0.297 0.000
J35.2 Hypertrophy of adenoids
0.703 0.297 0.000
M30.0 Polyarteritis nodosa
0.702 0.298 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
M25.42 Effusion of joint (Upper arm)
0.701 0.299 0.000
E61.1 Iron deficiency
0.700 0.300 0.000
H44 Disorders of globe
0.700 0.300 0.000
J43 Emphysema
0.699 0.301 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.698 0.301 0.000
E07.9 Disorder of thyroid, unspecified
0.698 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.302 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.697 0.303 0.000
Y40.9 Systemic antibiotic, unspecified
0.695 0.305 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.694 0.306 0.000
H04.6 Other changes in lachrymal passages
0.694 0.306 0.000
H04.0 Dacryoadenitis
0.694 0.306 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.694 0.306 0.000
Y40.7 Antifungal antibiotics, systemically used
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
Chapter VIII Diseases of the ear and mastoid process
0.693 0.307 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.692 0.308 0.000
Q79.6 Ehlers-Danlos syndrome
0.691 0.308 0.000
M60 Myositis
0.691 0.308 0.000
J06.9 Acute upper respiratory infection, unspecified
0.690 0.310 0.000
H16.9 Keratitis, unspecified
0.689 0.311 0.000
M13 Other arthritis
0.689 0.311 0.000
Y10-Y34 Event of undetermined intent
0.689 0.311 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.689 0.311 0.000
W00 Fall on same level involving ice and snow
0.688 0.312 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.688 0.312 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.688 0.312 0.000
Q26 Congenital malformations of great veins
0.687 0.313 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.687 0.313 0.000
E14.8 With unspecified complications
0.686 0.314 0.000
V28.9 Unspecified motorcycle rider injured in traffic accident
0.684 0.316 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.684 0.316 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.684 0.316 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.684 0.316 0.000
Q75 Other congenital malformations of skull and face bones
0.684 0.316 0.000
Q73 Reduction defects of unspecified limb
0.684 0.316 0.000
Q72 Reduction defects of lower limb
0.684 0.316 0.000
Q71 Reduction defects of upper limb
0.684 0.316 0.000
Q70 Syndactyly
0.684 0.316 0.000
Q69 Polydactyly
0.684 0.316 0.000
Q68 Other congenital musculoskeletal deformities
0.684 0.316 0.000
J98.2 Interstitial emphysema
0.684 0.316 0.000
E06.5 Other chronic thyroiditis
0.683 0.316 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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