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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs707928
log Bayes Factor = 282.972
Chromosome 6   position 31,742,590  (GRCh37) Explore rs707928 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
K90-K93 Other diseases of the digestive system
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
H43 Disorders of vitreous body
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
E14.3 With ophthalmic complications
0.999 0.001 0.000
H43-H45 Disorders of vitreous body and globe
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
K70-K77 Diseases of liver
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
L40-L45 Papulosquamous disorders
0.999 0.001 0.000
L43.9 Lichen planus, unspecified
0.998 0.002 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.998 0.002 0.000
E10.2 With renal complications
0.998 0.002 0.000
L43 Lichen planus
0.998 0.002 0.000
N04 Nephrotic syndrome
0.998 0.002 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.997 0.003 0.000
N17-N19 Renal failure
0.997 0.003 0.000
H43.1 Vitreous haemorrhage
0.997 0.003 0.000
H25-H28 Disorders of lens
0.997 0.003 0.000
H26.9 Cataract, unspecified
0.997 0.003 0.000
D64 Other anaemias
0.997 0.003 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.004 0.996
N18 Chronic renal failure
0.996 0.004 0.000
H26 Other cataract
0.995 0.005 0.000
E11 Non-insulin-dependent diabetes mellitus
0.995 0.005 0.000
D64.9 Anaemia, unspecified
0.995 0.005 0.000
D61 Other aplastic anaemias
0.995 0.005 0.000
K75 Other inflammatory liver diseases
0.994 0.006 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.994 0.006 0.000
K75.4 Autoimmune hepatitis
0.994 0.006 0.000
K90.9 Intestinal malabsorption, unspecified
0.993 0.007 0.000
N04.9 Unspecified
0.993 0.007 0.000
K50-K52 Noninfective enteritis and colitis
0.992 0.008 0.000
K52 Other non-infective gastro-enteritis and colitis
0.992 0.008 0.000
H43.8 Other disorders of vitreous body
0.991 0.009 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.991 0.009 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.990 0.010 0.000
D61.9 Aplastic anaemia, unspecified
0.990 0.010 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.984 0.016 0.000
K74 Fibrosis and cirrhosis of liver
0.973 0.027 0.000
L89 Decubitus ulcer
0.971 0.029 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.970 0.030 0.000
E10.5 With peripheral circulatory complications
0.970 0.030 0.000
H00.1 Chalazion
0.000 0.031 0.969
L92 Granulomatous disorders of skin and subcutaneous tissue
0.965 0.035 0.000
N18.9 Chronic renal failure, unspecified
0.963 0.037 0.000
K74.6 Other and unspecified cirrhosis of liver
0.959 0.041 0.000
H33 Retinal detachments and breaks
0.958 0.042 0.000
H34 Retinal vascular occlusions
0.952 0.048 0.000
E11.5 With peripheral circulatory complications
0.947 0.053 0.000
N05 Unspecified nephritic syndrome
0.947 0.053 0.000
K73 Chronic hepatitis, not elsewhere classified
0.943 0.057 0.000
E10.0 With coma
0.942 0.058 0.000
N18.3 Chronic kidney disease, stage 3
0.940 0.060 0.000
E06 Thyroiditis
0.939 0.061 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.932 0.068 0.000
L10-L14 Bullous disorders
0.922 0.078 0.000
H33.0 Retinal detachment with retinal break
0.921 0.079 0.000
E13 Other specified diabetes mellitus
0.921 0.079 0.000
L94 Other localised connective tissue disorders
0.919 0.081 0.000
E14.8 With unspecified complications
0.918 0.082 0.000
N05.2 Diffuse membranous glomerulonephritis
0.918 0.082 0.000
E11.0 With coma
0.911 0.089 0.000
L93 Lupus erythematosus
0.909 0.091 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.905 0.095 0.000
Q60-Q64 Congenital malformations of the urinary system
0.902 0.098 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.897 0.103 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.897 0.103 0.000
Q38.7 Pharyngeal pouch
0.893 0.107 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.891 0.109 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.888 0.112 0.000
L89.1 Stage II decubitus ulcer
0.887 0.113 0.000
E11.1 With ketoacidosis
0.885 0.115 0.000
C85.1 B-cell lymphoma, unspecified
0.883 0.117 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.881 0.119 0.000
D55-D59 Haemolytic anaemias
0.881 0.119 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.879 0.121 0.000
Q61 Cystic kidney disease
0.879 0.121 0.000
H30 Chorioretinal inflammation
0.876 0.124 0.000
N18.0 End-stage renal disease
0.875 0.125 0.000
G56.0 Carpal tunnel syndrome
0.869 0.131 0.000
N04.1 Focal and segmental glomerular lesions
0.868 0.132 0.000
H26.1 Traumatic cataract
0.867 0.133 0.000
E14.1 With ketoacidosis
0.865 0.135 0.000
H27 Other disorders of lens
0.862 0.138 0.000
L89.2 Stage III decubitus ulcer
0.862 0.138 0.000
N03 Chronic nephritic syndrome
0.860 0.140 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.860 0.140 0.000
K90.8 Other intestinal malabsorption
0.858 0.142 0.000
H34.8 Other retinal vascular occlusions
0.857 0.143 0.000
N05.1 Focal and segmental glomerular lesions
0.856 0.144 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.855 0.144 0.000
E13.9 Without complications
0.854 0.146 0.000
Q00-Q07 Congenital malformations of the nervous system
0.854 0.146 0.000
E14.6 With other specified complications
0.853 0.147 0.000
E11.6 With other specified complications
0.849 0.151 0.000
L13 Other bullous disorders
0.845 0.155 0.000
N18.4 Chronic kidney disease, stage 4
0.843 0.157 0.000
K73.9 Chronic hepatitis, unspecified
0.842 0.158 0.000
E06.3 Autoimmune thyroiditis
0.838 0.162 0.000
H34.2 Other retinal artery occlusions
0.838 0.162 0.000
E10.6 With other specified complications
0.836 0.164 0.000
L20-L30 Dermatitis and eczema
0.835 0.165 0.000
L94.0 Localised scleroderma [morphea]
0.835 0.165 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.833 0.167 0.000
N18.2 Chronic kidney disease, stage 2
0.833 0.167 0.000
E11.3 With ophthalmic complications
0.831 0.169 0.000
N04.2 Diffuse membranous glomerulonephritis
0.828 0.172 0.000
K75.8 Other specified inflammatory liver diseases
0.827 0.173 0.000
E14.5 With peripheral circulatory complications
0.827 0.173 0.000
N00 Acute nephritic syndrome
0.827 0.173 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.826 0.174 0.000
L28 Lichen simplex chronicus and prurigo
0.823 0.177 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.818 0.180 0.002
N18.1 Chronic kidney disease, stage 1
0.819 0.181 0.000
E11.4 With neurological complications
0.818 0.182 0.000
E40-E46 Malnutrition
0.818 0.182 0.000
Q61.3 Polycystic kidney, unspecified
0.817 0.183 0.000
L92.0 Granuloma annulare
0.817 0.183 0.000
D68 Other coagulation defects
0.816 0.184 0.000
D58 Other hereditary haemolytic anaemias
0.815 0.185 0.000
L28.0 Lichen simplex chronicus
0.815 0.185 0.000
L84 Corns and callosities
0.811 0.189 0.000
L93.0 Discoid lupus erythematosus
0.809 0.191 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.805 0.195 0.000
L94.9 Localised connective tissue disorder, unspecified
0.804 0.196 0.000
E11.7 With multiple complications
0.796 0.204 0.000
E14.4 With neurological complications
0.793 0.207 0.000
G59.0 Diabetic mononeuropathy
0.792 0.208 0.000
L13.0 Dermatitis herpetiformis
0.790 0.210 0.000
E14.2 Withrenal complications
0.789 0.211 0.000
H30.9 Chorioretinal inflammation, unspecified
0.787 0.213 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.784 0.216 0.000
Q65 Congenital deformities of hip
0.784 0.216 0.000
G56 Mononeuropathies of upper limb
0.781 0.219 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.780 0.220 0.000
E06.9 Thyroiditis, unspecified
0.780 0.220 0.000
N10-N16 Renal tubulo-interstitial diseases
0.777 0.223 0.000
E10.7 With multiple complications
0.775 0.225 0.000
H33.4 Traction detachment of retina
0.773 0.227 0.000
D61.0 Constitutional aplastic anaemia
0.772 0.228 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.772 0.228 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.770 0.230 0.000
H34.1 Central retinal artery occlusion
0.768 0.232 0.000
E07 Other disorders of thyroid
0.767 0.233 0.000
E06.5 Other chronic thyroiditis
0.765 0.235 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.765 0.235 0.000
H33.5 Other retinal detachments
0.764 0.236 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.760 0.239 0.001
N19 Unspecified renal failure
0.759 0.241 0.000
E10.8 With unspecified complications
0.759 0.241 0.000
H27.1 Dislocation of lens
0.759 0.241 0.000
Q35-Q37 Cleft lip and cleft palate
0.758 0.242 0.000
Q43 Other congenital malformations of intestine
0.755 0.245 0.000
L50-L54 Urticaria and erythema
0.752 0.248 0.000
Q40 Other congenital malformations of upper alimentary tract
0.751 0.249 0.000
E03.8 Other specified hypothyroidism
0.751 0.249 0.000
L80 Vitiligo
0.750 0.250 0.000
D61.1 Drug-induced aplastic anaemia
0.750 0.250 0.000
H31 Other disorders of choroid
0.749 0.251 0.000
Q61.0 Congenital single renal cyst
0.748 0.252 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.748 0.252 0.000
Q38.1 Ankyloglossia
0.748 0.252 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.746 0.254 0.000
H05 Disorders of orbit
0.745 0.254 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.745 0.255 0.000
D58.0 Hereditary spherocytosis
0.745 0.255 0.000
N11 Chronic tubulo-interstitial nephritis
0.744 0.255 0.000
K52.3 Indeterminate colitis
0.744 0.256 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.741 0.259 0.000
N18.5 Chronic kidney disease, stage 5
0.739 0.260 0.000
Chapter VI Diseases of the nervous system
0.738 0.262 0.000
K71 Toxic liver disease
0.735 0.265 0.000
L43.8 Other lichen planus
0.735 0.265 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.735 0.265 0.000
H43.9 Disorder of vitreous body, unspecified
0.734 0.266 0.000
E50-E64 Other nutritional deficiencies
0.733 0.267 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.724 0.276 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.722 0.277 0.000
N03.1 Focal and segmental glomerular lesions
0.721 0.279 0.000
K40-K46 Hernia
0.719 0.281 0.000
H06.2 Dysthyroid exophthalmos
0.718 0.281 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.718 0.281 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.717 0.283 0.000
H43.0 Vitreous prolapse
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.283 0.000
E16.3 Increased secretion of glucagon
0.716 0.283 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.716 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.716 0.284 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.716 0.284 0.000
L44 Other papulosquamous disorders
0.716 0.284 0.000
L41 Parapsoriasis
0.716 0.284 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.716 0.284 0.000
L93.1 Subacute cutaneous lupus erythematosus
0.716 0.284 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.716 0.284 0.000
L87 Transepidermal elimination disorders
0.716 0.284 0.000
L86 Keratoderma in diseases classified elsewhere
0.716 0.284 0.000
L43.3 Subacute (active) lichen planus
0.716 0.284 0.000
L43.2 Lichenoid drug reaction
0.716 0.284 0.000
L43.1 Bullous lichen planus
0.716 0.284 0.000
L43.0 Hypertrophic lichen planus
0.716 0.284 0.000
N04.8 Other
0.715 0.285 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.715 0.285 0.000
N04.6 Dense deposit disease
0.715 0.285 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.715 0.285 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.715 0.285 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.715 0.285 0.000
N04.0 Minor glomerular abnormality
0.715 0.285 0.000
D64.4 Congenital dyserythropoietic anaemia
0.714 0.285 0.000
D64.3 Other sideroblastic anaemias
0.714 0.285 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.714 0.285 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.714 0.285 0.000
D64.0 Hereditary sideroblastic anaemia
0.714 0.285 0.000
C88 Malignant immunoproliferative diseases
0.714 0.286 0.000
K43 Ventral hernia
0.714 0.286 0.000
D61.8 Other specified aplastic anaemias
0.713 0.287 0.000
D61.3 Idiopathic aplastic anaemia
0.713 0.287 0.000
D61.2 Aplastic anaemia due to other external agents
0.713 0.287 0.000
K75.2 Nonspecific reactive hepatitis
0.713 0.287 0.000
K75.1 Phlebitis of portal vein
0.713 0.287 0.000
D68.0 Von Willebrand's disease
0.712 0.288 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.711 0.289 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.711 0.289 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.711 0.289 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.711 0.289 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.710 0.290 0.000
H43.3 Other vitreous opacities
0.709 0.291 0.000
Q05 Spina bifida
0.707 0.293 0.000
N03.8 Other
0.706 0.294 0.000
L10 Pemphigus
0.704 0.296 0.000
Q61.9 Cystic kidney disease, unspecified
0.704 0.296 0.000
L83 Acanthosis nigricans
0.703 0.297 0.000
H00 Hordeolum and chalazion
0.207 0.297 0.496
N00.9 Unspecified
0.703 0.297 0.000
H55-H59 Other disorders of eye and adnexa
0.702 0.298 0.000
Q75 Other congenital malformations of skull and face bones
0.701 0.299 0.000
L42 Pityriasis rosea
0.700 0.300 0.000
E13.3 With ophthalmic complications
0.700 0.300 0.000
Q39 Congenital malformations of oesophagus
0.698 0.301 0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.698 0.302 0.000
K74.4 Secondary biliary cirrhosis
0.697 0.302 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.697 0.302 0.000
Q03 Congenital hydrocephalus
0.696 0.304 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.696 0.304 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.696 0.304 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.693 0.307 0.000
C83.3 Large cell (diffuse)
0.693 0.307 0.000
D68.8 Other specified coagulation defects
0.693 0.307 0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.692 0.308 0.000
L12 Pemphigoid
0.692 0.308 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.692 0.308 0.000
Q65.8 Other congenital deformities of hip
0.692 0.308 0.000
K72 Hepatic failure, not elsewhere classified
0.691 0.309 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.691 0.309 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.688 0.312 0.000
L20 Atopic dermatitis
0.687 0.313 0.000
L93.2 Other local lupus erythematosus
0.687 0.313 0.000
Q78 Other osteochondrodysplasias
0.687 0.313 0.000
E46 Unspecified protein-energy malnutrition
0.687 0.313 0.000
K74.1 Hepatic sclerosis
0.686 0.313 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.684 0.315 0.000
Q76 Congenital malformations of spine and bony thorax
0.684 0.316 0.000
K74.5 Biliary cirrhosis, unspecified
0.684 0.316 0.000
E11.2 With renal complications
0.683 0.316 0.000
H34.0 Transient retinal artery occlusion
0.683 0.317 0.000
H27.8 Other specified disorders of lens
0.681 0.319 0.000
C81 Hodgkin's disease
0.679 0.321 0.000
N05.6 Dense deposit disease
0.679 0.321 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.679 0.321 0.000
N05.0 Minor glomerular abnormality
0.679 0.321 0.000
H33.1 Retinoschisis and retinal cysts
0.678 0.322 0.000
Q61.2 Polycystic kidney, adult type
0.677 0.323 0.000
H26.3 Drug-induced cataract
0.677 0.323 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.676 0.324 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.676 0.324 0.000
K74.0 Hepatic fibrosis
0.675 0.325 0.000
L88 Pyoderma gangrenosum
0.674 0.326 0.000
H33.3 Retinal breaks without detachment
0.674 0.326 0.000
E06.4 Drug-induced thyroiditis
0.673 0.327 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.673 0.327 0.000
E06.0 Acute thyroiditis
0.673 0.327 0.000
H05.8 Other disorders of orbit
0.670 0.329 0.000
Q38.8 Other congenital malformations of pharynx
0.668 0.331 0.000
Q38.6 Other congenital malformations of mouth
0.668 0.331 0.000
Q38.5 Congenital malformations of palate, not elsewhere classified
0.668 0.331 0.000
Q38.4 Congenital malformations of salivary glands and ducts
0.668 0.331 0.000
Q38.3 Other congenital malformations of tongue
0.668 0.331 0.000
Q38.2 Macroglossia
0.668 0.331 0.000
Q38.0 Congenital malformations of lips, not elsewhere classified
0.668 0.331 0.000
L11 Other acantholytic disorders
0.668 0.332 0.000
Q44.6 Cystic disease of liver
0.666 0.334 0.000
D59 Acquired haemolytic anaemia
0.664 0.336 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.664 0.336 0.000
K74.3 Primary biliary cirrhosis
0.664 0.336 0.000
K52.1 Toxic gastro-enteritis and colitis
0.663 0.337 0.000
H26.0 Infantile, juvenile and presenile cataract
0.663 0.337 0.000
L14 Bullous disorders in diseases classified elsewhere
0.661 0.339 0.000
E11.8 With unspecified complications
0.661 0.339 0.000
E13.8 With unspecified complications
0.660 0.340 0.000
E13.7 With multiple complications
0.660 0.340 0.000
E13.6 With other specified complications
0.660 0.340 0.000
E13.5 With peripheral circulatory complications
0.660 0.340 0.000
E13.4 With neurological complications
0.660 0.340 0.000
E13.2 With renal complications
0.660 0.340 0.000
E13.1 With ketoacidosis
0.660 0.340 0.000
E13.0 With coma
0.660 0.340 0.000
L94.6 Ainhum
0.659 0.341 0.000
L94.5 Poikiloderma vasculare atrophicans
0.659 0.341 0.000
L94.4 Gottron's papules
0.659 0.341 0.000
L94.3 Sclerodactyly
0.659 0.341 0.000
L94.1 Linear scleroderma
0.659 0.341 0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue
0.658 0.342 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.656 0.343 0.000
H46 Optic neuritis
0.656 0.344 0.000
Q45 Other congenital malformations of digestive system
0.655 0.345 0.000
N17 Acute renal failure
0.654 0.346 0.000
L52 Erythema nodosum
0.653 0.347 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.652 0.348 0.000
G70-G73 Diseases of myoneural junction and muscle
0.652 0.348 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.651 0.349 0.000
D68.1 Hereditary factor XI deficiency
0.650 0.350 0.000
Chapter XXII Codes for special purposes
0.649 0.351 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.647 0.353 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.647 0.353 0.000
N10 Acute tubulo-interstitial nephritis
0.646 0.354 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.646 0.354 0.000
D68.6 Other Thrombophilia
0.646 0.354 0.000
Q44.4 Choledochal cyst
0.644 0.356 0.000
C85.0 Lymphosarcoma
0.643 0.357 0.000
E06.1 Subacute thyroiditis
0.642 0.358 0.000
H31.3 Choroidal haemorrhage and rupture
0.641 0.359 0.000
Q61.4 Renal dysplasia
0.641 0.359 0.000
N02 Recurrent and persistent haematuria
0.640 0.360 0.000
Q61.5 Medullary cystic kidney
0.639 0.361 0.000
H05.2 Exophthalmic conditions
0.639 0.361 0.000
H52 Disorders of refraction and accommodation
0.639 0.361 0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.639 0.361 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.639 0.361 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.638 0.362 0.000
L94.8 Other specified localised connective tissue disorders
0.633 0.367 0.000
Q73 Reduction defects of unspecified limb
0.632 0.368 0.000
Q72 Reduction defects of lower limb
0.632 0.368 0.000
Q71 Reduction defects of upper limb
0.632 0.368 0.000
Q70 Syndactyly
0.632 0.368 0.000
Q69 Polydactyly
0.632 0.368 0.000
Q68 Other congenital musculoskeletal deformities
0.632 0.368 0.000
C92 Myeloid leukaemia
0.632 0.368 0.000
D57 Sickle-cell disorders
0.631 0.368 0.000
D55 Anaemia due to enzyme disorders
0.631 0.368 0.000
H52.1 Myopia
0.631 0.369 0.000
Q44.5 Other congenital malformations of bile ducts
0.631 0.369 0.000
D67 Hereditary factor IX deficiency
0.630 0.370 0.000
Q61.8 Other cystic kidney diseases
0.630 0.370 0.000
Q61.1 Polycystic kidney, infantile type
0.630 0.370 0.000
N18.8 Other chronic renal failure
0.629 0.370 0.000
H30.8 Other chorioretinal inflammations
0.628 0.372 0.000
H30.2 Posterior cyclitis
0.628 0.372 0.000
H30.1 Disseminated chorioretinal inflammation
0.628 0.372 0.000
H30.0 Focal chorioretinal inflammation
0.628 0.372 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.625 0.375 0.000
C81.1 Nodular sclerosis
0.621 0.379 0.000
L95.8 Other vasculitis limited to skin
0.621 0.379 0.000
H27.9 Disorder of lens, unspecified
0.618 0.382 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.618 0.382 0.000
G52 Disorders of other cranial nerves
0.618 0.382 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.618 0.382 0.000
Q65.2 Congenital dislocation of hip, unspecified
0.617 0.383 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.617 0.383 0.000
N03.6 Dense deposit disease
0.617 0.383 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.617 0.383 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.617 0.383 0.000
N03.2 Diffuse membranous glomerulonephritis
0.617 0.383 0.000
N03.0 Minor glomerular abnormality
0.617 0.383 0.000
H34.9 Retinal vascular occlusion, unspecified
0.616 0.383 0.000
D64.8 Other specified anaemias
0.616 0.384 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.615 0.385 0.000
G56.4 Causalgia
0.614 0.385 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.613 0.387 0.000
Q06 Other congenital malformations of spinal cord
0.612 0.388 0.000
Q01 Encephalocele
0.612 0.388 0.000
Q00 Anencephaly and similar malformations
0.612 0.388 0.000
Q02 Microcephaly
0.612 0.388 0.000
Q07 Other congenital malformations of nervous system
0.610 0.389 0.000
E05.8 Other thyrotoxicosis
0.610 0.390 0.000
Q04 Other congenital malformations of brain
0.610 0.390 0.000
G56.8 Other mononeuropathies of upper limb
0.610 0.390 0.000
N11.1 Chronic obstructive pyelonephritis
0.609 0.391 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.606 0.394 0.000
L13.9 Bullous disorder, unspecified
0.606 0.394 0.000
L13.8 Other specified bullous disorders
0.606 0.394 0.000
L13.1 Subcorneal pustular dermatitis
0.606 0.394 0.000
L21 Seborrhoeic dermatitis
0.606 0.394 0.000
D68.9 Coagulation defect, unspecified
0.604 0.396 0.000
Q40.3 Congenital malformation of stomach, unspecified
0.602 0.398 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.602 0.398 0.000
E14.9 Without complications
0.601 0.399 0.000
N15 Other renal tubulo-interstitial diseases
0.601 0.399 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.600 0.400 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.600 0.400 0.000
L24 Irritant contact dermatitis
0.599 0.401 0.000
L26 Exfoliative dermatitis
0.599 0.401 0.000
L22 Diaper [napkin] dermatitis
0.599 0.401 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.598 0.402 0.000
N25-N29 Other disorders of kidney and ureter
0.597 0.403 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.596 0.404 0.000
H43.2 Crystalline deposits in vitreous body
0.596 0.404 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.595 0.405 0.000
N00.8 Other
0.593 0.407 0.000
N00.7 Diffuse crescentic glomerulonephritis
0.593 0.407 0.000
N00.6 Dense deposit disease
0.593 0.407 0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.593 0.407 0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.593 0.407 0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.593 0.407 0.000
N00.2 Diffuse membranous glomerulonephritis
0.593 0.407 0.000
N00.1 Focal and segmental glomerular lesions
0.593 0.407 0.000
N00.0 Minor glomerular abnormality
0.593 0.407 0.000
Q44.7 Other congenital malformations of liver
0.592 0.408 0.000
Q44.3 Congenital stenosis and stricture of bile ducts
0.592 0.408 0.000
Q44.2 Atresia of bile ducts
0.592 0.408 0.000
Q44.1 Other congenital malformations of gallbladder
0.592 0.408 0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder
0.592 0.408 0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis
0.591 0.409 0.000
E58 Dietary calcium deficiency
0.591 0.409 0.000
E07.9 Disorder of thyroid, unspecified
0.591 0.409 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.590 0.410 0.000
L28.2 Other prurigo
0.590 0.410 0.000
N05.8 Other
0.588 0.412 0.000
Q43.3 Congenital malformations of intestinal fixation
0.586 0.413 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.586 0.414 0.000
E45 Retarded development following protein-energy malnutrition
0.586 0.414 0.000
E43 Unspecified severe protein-energy malnutrition
0.586 0.414 0.000
E42 Marasmic kwashiorkor
0.586 0.414 0.000
E41 Nutritional marasmus
0.586 0.414 0.000
E40 Kwashiorkor
0.586 0.414 0.000
D68.5 Primary Thrombophilia
0.586 0.414 0.000
L28.1 Prurigo nodularis
0.585 0.415 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.585 0.415 0.000
D58.1 Hereditary elliptocytosis
0.585 0.415 0.000
Q03.0 Malformations of aqueduct of Sylvius
0.583 0.417 0.000
N02.2 Diffuse membranous glomerulonephritis
0.582 0.418 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.582 0.418 0.000
L20.9 Atopic dermatitis, unspecified
0.581 0.419 0.000
L25 Unspecified contact dermatitis
0.581 0.419 0.000
D58.2 Other haemoglobinopathies
0.580 0.420 0.000
Q66 Congenital deformities of feet
0.579 0.421 0.000
H55 Nystagmus and other irregular eye movements
0.578 0.422 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.578 0.422 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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