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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117111
log Bayes Factor = 217.05
Chromosome 6   position 32,338,400  (GRCh37) Explore rs3117111 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
M07 Psoriatic and enteropathic arthropathies
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.004 0.996
H30-H36 Disorders of choroid and retina
0.000 0.004 0.996
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
L40.9 Psoriasis, unspecified
0.000 0.004 0.996
M35 Other systemic involvement of connective tissue
0.000 0.005 0.995
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
M07.3 Other psoriatic arthropathies
0.000 0.005 0.995
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
E10.5 With peripheral circulatory complications
0.000 0.007 0.993
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
# Top node
0.000 0.008 0.992
J33.8 Other polyp of sinus
0.000 0.009 0.991
E11.1 With ketoacidosis
0.000 0.009 0.991
Chapter VII Diseases of the eye and adnexa
0.000 0.009 0.991
I10 Essential (primary) hypertension
0.000 0.009 0.991
I10-I15 Hypertensive diseases
0.000 0.010 0.990
M20-M25 Other joint disorders
0.000 0.011 0.989
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.013 0.987
L43 Lichen planus
0.000 0.016 0.984
Chapter IX Diseases of the circulatory system
0.000 0.018 0.982
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.021 0.979
E10.2 With renal complications
0.000 0.025 0.975
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.029 0.971
E06 Thyroiditis
0.000 0.030 0.970
H40-H42 Glaucoma
0.000 0.030 0.970
I22 Subsequent myocardial infarction
0.000 0.031 0.969
I20-I25 Ischaemic heart diseases
0.000 0.032 0.968
L43.9 Lichen planus, unspecified
0.000 0.039 0.961
H40 Glaucoma
0.000 0.044 0.956
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.045 0.955
H40.9 Glaucoma, unspecified
0.000 0.045 0.955
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.045 0.955
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.046 0.954
E10.8 With unspecified complications
0.000 0.046 0.954
E06.3 Autoimmune thyroiditis
0.000 0.048 0.952
M34 Systemic sclerosis
0.000 0.052 0.948
I12 Hypertensive renal disease
0.000 0.052 0.948
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.052 0.948
H34 Retinal vascular occlusions
0.000 0.053 0.947
M06.0 Seronegative rheumatoid arthritis
0.000 0.056 0.944
E10.0 With coma
0.000 0.058 0.942
M06.3 Rheumatoid nodule
0.000 0.060 0.940
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.062 0.938
M65-M68 Disorders of synovium and tendon
0.000 0.064 0.936
I12.9 Hypertensive renal disease without renal failure
0.000 0.071 0.929
E78.2 Mixed hyperlipidaemia
0.000 0.077 0.923
M65 Synovitis and tenosynovitis
0.000 0.082 0.918
M45-M49 Spondylopathies
0.000 0.086 0.914
M45 Ankylosing spondylitis
0.000 0.088 0.912
M06.4 Inflammatory polyarthropathy
0.000 0.092 0.908
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.104 0.896
E11.2 With renal complications
0.000 0.104 0.896
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.105 0.895
E07 Other disorders of thyroid
0.000 0.105 0.895
E78.1 Pure hyperglyceridaemia
0.000 0.107 0.893
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.108 0.892
E88 Other metabolic disorders
0.000 0.111 0.889
H35 Other retinal disorders
0.000 0.113 0.887
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.120 0.880
E11.5 With peripheral circulatory complications
0.000 0.126 0.874
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.131 0.869
M34.1 CR(E)ST syndrome
0.000 0.135 0.865
M35.1 Other overlap syndromes
0.000 0.135 0.865
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.137 0.863
G37.8 Other specified demyelinating diseases of central nervous system
0.860 0.140 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.142 0.858
M35.7 Hypermobility syndrome
0.000 0.144 0.856
L40.8 Other psoriasis
0.000 0.145 0.855
L43.8 Other lichen planus
0.000 0.145 0.855
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.148 0.852
M34.9 Systemic sclerosis, unspecified
0.000 0.151 0.849
H35.4 Peripheral retinal degeneration
0.000 0.156 0.844
H34.8 Other retinal vascular occlusions
0.000 0.158 0.842
H35.8 Other specified retinal disorders
0.000 0.162 0.838
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.164 0.836
M06.34 Rheumatoid nodule (Hand)
0.000 0.167 0.833
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.172 0.828
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.174 0.826
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.177 0.823
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.179 0.821
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.179 0.821
H34.2 Other retinal artery occlusions
0.000 0.182 0.818
E10.6 With other specified complications
0.000 0.183 0.817
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.184 0.816
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.189 0.811
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.192 0.808
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.192 0.807
E07.9 Disorder of thyroid, unspecified
0.000 0.199 0.801
E11.8 With unspecified complications
0.000 0.202 0.798
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.205 0.795
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.206 0.794
E14.4 With neurological complications
0.000 0.209 0.791
E03.8 Other specified hypothyroidism
0.000 0.211 0.789
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.213 0.787
I15 Secondary hypertension
0.000 0.215 0.784
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.217 0.783
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.217 0.783
M30 Polyarteritis nodosa and related conditions
0.000 0.221 0.779
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.221 0.779
M31 Other necrotising vasculopathies
0.000 0.223 0.777
E74 Other disorders of carbohydrate metabolism
0.000 0.226 0.774
I22.8 Subsequent myocardial infarction of other sites
0.000 0.230 0.770
H40.4 Glaucoma secondary to eye inflammation
0.000 0.231 0.769
E83 Disorders of mineral metabolism
0.355 0.234 0.411
M35.2 Behcet's disease
0.000 0.237 0.763
H43-H45 Disorders of vitreous body and globe
0.000 0.241 0.759
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.244 0.756
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.244 0.755
E14.5 With peripheral circulatory complications
0.000 0.247 0.753
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.254 0.746
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.262 0.738
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.266 0.734
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.733 0.267 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.267 0.733
L40.3 Pustulosis palmaris et plantaris
0.000 0.268 0.732
E14.2 Withrenal complications
0.000 0.269 0.731
H40.5 Glaucoma secondary to other eye disorders
0.000 0.269 0.731
G36 Other acute disseminated demyelination
0.729 0.271 0.000
H35.6 Retinal haemorrhage
0.000 0.272 0.728
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.275 0.725
M14 Arthropathies in other diseases classified elsewhere
0.000 0.276 0.724
H34.9 Retinal vascular occlusion, unspecified
0.000 0.277 0.723
E89.0 Postprocedural hypothyroidism
0.000 0.279 0.721
H34.1 Central retinal artery occlusion
0.000 0.279 0.721
H30 Chorioretinal inflammation
0.000 0.281 0.719
H35.7 Separation of retinal layers
0.000 0.282 0.718
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
M65.1 Other infective (teno)synovitis
0.000 0.283 0.717
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.715
M07.5 Arthropathy in ulcerative colitis
0.000 0.285 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.285 0.715
M07.2 Psoriatic spondylitis
0.000 0.285 0.715
M07.1 Arthritis mutilans
0.000 0.285 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.714
E40-E46 Malnutrition
0.000 0.286 0.714
D64.9 Anaemia, unspecified
0.000 0.286 0.714
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.286 0.714
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.286 0.714
M35.5 Multifocal fibrosclerosis
0.000 0.286 0.714
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.287 0.713
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.287 0.713
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.287 0.713
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.287 0.713
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.287 0.713
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.287 0.713
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.289 0.711
I13 Hypertensive heart and renal disease
0.000 0.290 0.710
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.291 0.709
E88.2 Lipomatosis, not elsewhere classified
0.000 0.291 0.709
E88.8 Other specified metabolic disorders
0.000 0.291 0.709
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.293 0.707
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.294 0.706
L43.3 Subacute (active) lichen planus
0.000 0.294 0.705
L43.2 Lichenoid drug reaction
0.000 0.294 0.705
L43.1 Bullous lichen planus
0.000 0.294 0.705
L43.0 Hypertrophic lichen planus
0.000 0.294 0.705
D64 Other anaemias
0.000 0.295 0.705
I00-I02 Acute rheumatic fever
0.000 0.296 0.704
D60-D64 Aplastic and other anaemias
0.000 0.297 0.703
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
I11 Hypertensive heart disease
0.000 0.301 0.699
E13 Other specified diabetes mellitus
0.000 0.301 0.699
E11.6 With other specified complications
0.000 0.303 0.697
L40.0 Psoriasis vulgaris
0.000 0.304 0.696
E06.5 Other chronic thyroiditis
0.000 0.304 0.696
E06.4 Drug-induced thyroiditis
0.000 0.304 0.696
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.304 0.696
E06.1 Subacute thyroiditis
0.000 0.304 0.696
E06.0 Acute thyroiditis
0.000 0.304 0.696
M34.8 Other forms of systemic sclerosis
0.000 0.304 0.696
H42 Glaucoma in diseases classified elsewhere
0.000 0.304 0.696
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.305 0.695
E79 Disorders of purine and pyrimidine metabolism
0.000 0.307 0.692
L57.0 Actinic keratosis
0.000 0.309 0.691
E07.8 Other specified disorders of thyroid
0.000 0.311 0.689
H43 Disorders of vitreous body
0.000 0.312 0.688
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.313 0.687
H40.6 Glaucoma secondary to drugs
0.000 0.315 0.685
H40.3 Glaucoma secondary to eye trauma
0.000 0.315 0.685
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.317 0.683
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.317 0.683
E16.1 Other hypoglycaemia
0.000 0.318 0.682
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.320 0.680
M34.0 Progressive systemic sclerosis
0.000 0.320 0.680
H34.0 Transient retinal artery occlusion
0.000 0.321 0.679
E78.4 Other hyperlipidaemia
0.000 0.322 0.678
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.323 0.677
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.323 0.677
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.323 0.677
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.323 0.677
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.323 0.677
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.323 0.677
M12 Other specific arthropathies
0.000 0.323 0.676
M91-M94 Chondropathies
0.000 0.324 0.676
M31.6 Other giant cell arteritis
0.000 0.324 0.676
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.326 0.674
M06.38 Rheumatoid nodule (Other)
0.000 0.326 0.674
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.326 0.674
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.326 0.674
M06.33 Rheumatoid nodule (Forearm)
0.000 0.326 0.674
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.326 0.674
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.326 0.674
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.329 0.671
M07.6 Other enteropathic arthropathies
0.000 0.332 0.668
E84 Cystic fibrosis
0.000 0.333 0.666
M49 Spondylopathies in diseases classified elsewhere
0.000 0.337 0.663
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.659
H40.1 Primary open-angle glaucoma
0.000 0.341 0.659
M65.2 Calcific tendinitis
0.000 0.342 0.658
M65.0 Abscess of tendon sheath
0.000 0.342 0.658
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.344 0.656
M86-M90 Other osteopathies
0.000 0.346 0.654
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.346 0.654
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.346 0.654
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.346 0.654
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.346 0.654
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.346 0.654
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.346 0.654
Chapter VIII Diseases of the ear and mastoid process
0.000 0.348 0.652
L10-L14 Bullous disorders
0.000 0.348 0.652
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.349 0.651
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.349 0.651
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.349 0.651
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.349 0.651
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.349 0.651
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.349 0.651
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.349 0.651
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.349 0.651
H35.2 Other proliferative retinopathy
0.000 0.350 0.650
E06.9 Thyroiditis, unspecified
0.000 0.351 0.649
H40.0 Glaucoma suspect
0.000 0.352 0.648
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.358 0.642
E07.1 Dyshormogenetic goitre
0.000 0.359 0.641
E07.0 Hypersecretion of calcitonin
0.000 0.359 0.641
E88.3 Tumour lysis syndrome
0.000 0.359 0.641
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.360 0.640
E88.9 Metabolic disorder, unspecified
0.000 0.362 0.637
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.362 0.637
M32 Systemic lupus erythematosus
0.000 0.363 0.637
H35.1 Retinopathy of prematurity
0.000 0.364 0.636
M66 Spontaneous rupture of synovium and tendon
0.000 0.365 0.635
E11.4 With neurological complications
0.000 0.369 0.631
M11 Other crystal arthropathies
0.000 0.375 0.624
I21 Acute myocardial infarction
0.000 0.376 0.624
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.377 0.623
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.377 0.623
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.377 0.623
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.377 0.623
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.377 0.623
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.377 0.623
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.377 0.623
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.377 0.623
H60-H62 Diseases of external ear
0.000 0.379 0.621
L42 Pityriasis rosea
0.000 0.383 0.617
I15.9 Seconday hypertension, unspecified
0.000 0.385 0.615
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.387 0.613
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.387 0.612
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.388 0.612
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.388 0.611
E05.8 Other thyrotoxicosis
0.000 0.390 0.610
H33 Retinal detachments and breaks
0.000 0.392 0.608
H43.3 Other vitreous opacities
0.000 0.393 0.607
I15.1 Hypertension secondary to other renal disorders
0.000 0.397 0.603
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.399 0.601
M86 Osteomyelitis
0.000 0.399 0.601
E73 Lactose intolerance
0.000 0.400 0.600
E89.4 Postprocedural ovarian failure
0.000 0.403 0.596
M33 Dermatopolymyositis
0.000 0.406 0.594
I23 Certain current complications following acute myocardial infarction
0.000 0.406 0.593
M30.0 Polyarteritis nodosa
0.000 0.407 0.593
M60-M63 Disorders of muscles
0.000 0.409 0.591
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.410 0.590
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.410 0.589
H43.9 Disorder of vitreous body, unspecified
0.000 0.414 0.586
M35.0 Sicca syndrome [Sjogren]
0.000 0.414 0.586
L55 Sunburn
0.000 0.415 0.585
M14.6 Neuropathic arthropathy
0.000 0.416 0.584
M31.3 Wegener's granulomatosis
0.000 0.417 0.583
E65-E68 Obesity and other hyperalimentation
0.000 0.418 0.582
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.422 0.578
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.428 0.572
M86.9 Osteomyelitis, unspecified
0.000 0.428 0.572
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.430 0.570
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.430 0.570
E89.5 Postprocedural testicular hypofunction
0.000 0.430 0.570
E89.1 Postprocedural hypoinsulinaemia
0.000 0.430 0.570
H61 Other disorders of external ear
0.000 0.430 0.570
E11.0 With coma
0.000 0.431 0.569
M31.9 Necrotising vasculopathy, unspecified
0.000 0.432 0.567
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.434 0.566
M31.1 Thrombotic microangiopathy
0.000 0.435 0.565
M10 Gout
0.000 0.435 0.565
M15-M19 Arthrosis
0.000 0.436 0.564
E78.8 Other disorders of lipoprotein metabolism
0.000 0.437 0.563
I15.8 Other secondary hypertension
0.000 0.437 0.562
I15.2 Hypertension secondary to endocrine disorders
0.000 0.437 0.562
E03.1 Congenital hypothyroidism without goitre
0.000 0.438 0.561
M80-M85 Disorders of bone density and structure
0.000 0.439 0.561
I21.9 Acute myocardial infarction, unspecified
0.000 0.440 0.560
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.441 0.559
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.441 0.559
M30.2 Juvenile polyarteritis
0.000 0.441 0.559
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.442 0.558
M31.8 Other specified necrotising vasculopathies
0.000 0.443 0.557
M31.7 Microscopic polyangiitis
0.000 0.443 0.557
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.443 0.557
M31.2 Lethal midline granuloma
0.000 0.443 0.557
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.445 0.555
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.445 0.555
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.445 0.555
E74.2 Disorders of galactose metabolism
0.000 0.445 0.555
E74.1 Disorders of fructose metabolism
0.000 0.445 0.555
E74.0 Glycogen storage disease
0.000 0.445 0.555
M00-M03 Infectious arthropathies
0.000 0.445 0.555
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.448 0.552
E83.8 Other disorders of mineral metabolism
0.255 0.451 0.295
E83.2 Disorders of zinc metabolism
0.255 0.451 0.295
E83.0 Disorders of copper metabolism
0.255 0.451 0.295
I15.0 Renovascular hypertension
0.000 0.451 0.549
E20-E35 Disorders of other endocrine glands
0.000 0.451 0.549
D62 Acute posthaemorrhagic anaemia
0.000 0.454 0.546
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.454 0.545
I24 Other acute ischaemic heart diseases
0.000 0.455 0.545
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.455 0.544
H60 Otitis externa
0.000 0.456 0.544
E89.3 Postprocedural hypopituitarism
0.000 0.457 0.543
I70 Atherosclerosis
0.000 0.461 0.539
G36.0 Neuromyelitis optica [Devic]
0.537 0.462 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.276 0.463 0.261
L58 Radiodermatitis
0.000 0.466 0.534
H33.3 Retinal breaks without detachment
0.000 0.466 0.534
L20-L30 Dermatitis and eczema
0.000 0.471 0.529
L57.5 Actinic granuloma
0.000 0.475 0.525
L57.3 Poikiloderma of Civatte
0.000 0.475 0.525
L57.2 Cutis rhomboidalis nuchae
0.000 0.475 0.525
L57.1 Actinic reticuloid
0.000 0.475 0.525
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.475 0.525
G36.9 Acute disseminated demyelination, unspecified
0.523 0.477 0.000
G36.8 Other specified acute disseminated demyelination
0.523 0.477 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.523 0.477 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.480 0.520
H43.2 Crystalline deposits in vitreous body
0.000 0.481 0.519
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.481 0.519
M14.4 Arthropathy in amyloidosis
0.000 0.481 0.519
M14.3 Lipoid dermatoarthritis
0.000 0.481 0.519
M14.2 Diabetic arthropathy
0.000 0.481 0.519
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.481 0.519
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.481 0.519
H61.0 Perichondritis of external ear
0.000 0.483 0.517
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.483 0.517
H46 Optic neuritis
0.000 0.484 0.516
H30.8 Other chorioretinal inflammations
0.000 0.484 0.515
H30.2 Posterior cyclitis
0.000 0.484 0.515
H30.1 Disseminated chorioretinal inflammation
0.000 0.484 0.515
H30.0 Focal chorioretinal inflammation
0.000 0.484 0.515
H35.5 Hereditary retinal dystrophy
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514
M06.14 Adult-onset Still's disease (Hand)
0.000 0.486 0.514
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.486 0.514
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.486 0.514
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.486 0.514
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.486 0.514
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.486 0.514
M06.28 Rheumatoid bursitis (Other)
0.000 0.486 0.514
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.486 0.514
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.486 0.514
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.486 0.514
M06.24 Rheumatoid bursitis (Hand)
0.000 0.486 0.514
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.486 0.514
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.486 0.514
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.486 0.514
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.486 0.514
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.486 0.514
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.486 0.514
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.486 0.514
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.486 0.514
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.486 0.514
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.486 0.514
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.486 0.514
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.486 0.514
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.486 0.514
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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