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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3117138
log Bayes Factor = 217.565
Chromosome 6   position 32,306,970  (GRCh37) Explore rs3117138 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
J33 Nasal polyp
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
J33.0 Polyp of nasal cavity
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.001 0.999
E11.3 With ophthalmic complications
0.000 0.001 0.999
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.001 0.999
J33.9 Nasal polyp, unspecified
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M07 Psoriatic and enteropathic arthropathies
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.000 0.003 0.997
M07.3 Other psoriatic arthropathies
0.000 0.003 0.997
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.000 0.004 0.996
I10 Essential (primary) hypertension
0.000 0.004 0.996
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
L40.9 Psoriasis, unspecified
0.000 0.005 0.995
M35 Other systemic involvement of connective tissue
0.000 0.005 0.995
I10-I15 Hypertensive diseases
0.000 0.005 0.995
G37.9 Demyelinating disease of central nervous system, unspecified
0.994 0.006 0.000
J33.8 Other polyp of sinus
0.000 0.007 0.993
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.007 0.993
# Top node
0.000 0.007 0.993
E10.5 With peripheral circulatory complications
0.000 0.007 0.993
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.008 0.992
E11.1 With ketoacidosis
0.000 0.009 0.991
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.010 0.990
Chapter VII Diseases of the eye and adnexa
0.000 0.011 0.989
M20-M25 Other joint disorders
0.000 0.012 0.988
Chapter IX Diseases of the circulatory system
0.000 0.016 0.984
L43 Lichen planus
0.000 0.016 0.984
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.017 0.983
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.024 0.976
E10.2 With renal complications
0.000 0.024 0.976
I22 Subsequent myocardial infarction
0.000 0.034 0.966
I20-I25 Ischaemic heart diseases
0.000 0.035 0.965
I12 Hypertensive renal disease
0.000 0.036 0.964
E06 Thyroiditis
0.000 0.038 0.962
L43.9 Lichen planus, unspecified
0.000 0.040 0.960
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.041 0.959
E10.8 With unspecified complications
0.000 0.046 0.954
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.047 0.953
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.048 0.952
I12.9 Hypertensive renal disease without renal failure
0.000 0.050 0.950
H40-H42 Glaucoma
0.000 0.050 0.950
M06.0 Seronegative rheumatoid arthritis
0.000 0.052 0.948
M34 Systemic sclerosis
0.000 0.052 0.948
M65-M68 Disorders of synovium and tendon
0.000 0.052 0.948
M45-M49 Spondylopathies
0.000 0.058 0.942
E10.0 With coma
0.000 0.058 0.942
E06.3 Autoimmune thyroiditis
0.000 0.059 0.941
M45 Ankylosing spondylitis
0.000 0.059 0.941
M06.3 Rheumatoid nodule
0.000 0.060 0.940
H34 Retinal vascular occlusions
0.000 0.061 0.939
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.061 0.939
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.067 0.933
M65 Synovitis and tenosynovitis
0.000 0.067 0.933
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.074 0.926
H40 Glaucoma
0.000 0.078 0.922
H40.9 Glaucoma, unspecified
0.000 0.081 0.919
M06.4 Inflammatory polyarthropathy
0.000 0.092 0.908
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.093 0.907
E78.2 Mixed hyperlipidaemia
0.000 0.096 0.904
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.102 0.898
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.104 0.896
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.107 0.893
E88 Other metabolic disorders
0.000 0.110 0.890
E11.2 With renal complications
0.000 0.111 0.889
E78.1 Pure hyperglyceridaemia
0.000 0.114 0.885
E07 Other disorders of thyroid
0.000 0.123 0.877
H35 Other retinal disorders
0.000 0.123 0.877
E11.5 With peripheral circulatory complications
0.000 0.125 0.875
M34.1 CR(E)ST syndrome
0.000 0.135 0.865
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.136 0.864
G37.8 Other specified demyelinating diseases of central nervous system
0.860 0.140 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.142 0.858
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.142 0.858
M35.7 Hypermobility syndrome
0.000 0.144 0.856
L43.8 Other lichen planus
0.000 0.145 0.855
M35.1 Other overlap syndromes
0.000 0.146 0.854
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.148 0.852
M34.9 Systemic sclerosis, unspecified
0.000 0.151 0.849
L40.8 Other psoriasis
0.000 0.154 0.846
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.158 0.842
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.164 0.836
H35.4 Peripheral retinal degeneration
0.000 0.165 0.835
M06.34 Rheumatoid nodule (Hand)
0.000 0.166 0.834
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.167 0.833
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.168 0.832
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.169 0.831
H34.8 Other retinal vascular occlusions
0.000 0.169 0.831
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.171 0.829
D64.9 Anaemia, unspecified
0.000 0.172 0.828
H35.8 Other specified retinal disorders
0.000 0.175 0.825
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.176 0.824
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.179 0.821
D64 Other anaemias
0.000 0.180 0.820
D60-D64 Aplastic and other anaemias
0.000 0.182 0.818
E10.6 With other specified complications
0.000 0.183 0.817
E11.8 With unspecified complications
0.000 0.189 0.811
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.189 0.811
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.192 0.808
H34.2 Other retinal artery occlusions
0.000 0.196 0.804
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.200 0.800
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.201 0.799
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.000 0.202 0.798
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.207 0.793
E14.4 With neurological complications
0.000 0.209 0.791
I15 Secondary hypertension
0.000 0.211 0.789
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.217 0.783
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.000 0.217 0.783
M30 Polyarteritis nodosa and related conditions
0.000 0.221 0.779
E03.8 Other specified hypothyroidism
0.000 0.221 0.779
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.224 0.776
E83 Disorders of mineral metabolism
0.360 0.228 0.412
E07.9 Disorder of thyroid, unspecified
0.000 0.231 0.769
I22.8 Subsequent myocardial infarction of other sites
0.000 0.231 0.769
E74 Other disorders of carbohydrate metabolism
0.000 0.235 0.765
H43-H45 Disorders of vitreous body and globe
0.000 0.237 0.763
M35.2 Behcet's disease
0.000 0.238 0.762
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.239 0.761
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.243 0.757
E14.5 With peripheral circulatory complications
0.000 0.247 0.753
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.248 0.752
M31 Other necrotising vasculopathies
0.000 0.253 0.747
H40.4 Glaucoma secondary to eye inflammation
0.000 0.259 0.741
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.263 0.737
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.264 0.736
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.733 0.267 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.268 0.732
E14.2 Withrenal complications
0.000 0.269 0.731
H35.6 Retinal haemorrhage
0.000 0.271 0.729
G36 Other acute disseminated demyelination
0.729 0.271 0.000
M65.1 Other infective (teno)synovitis
0.000 0.272 0.728
E89.0 Postprocedural hypothyroidism
0.000 0.275 0.725
M14 Arthropathies in other diseases classified elsewhere
0.000 0.276 0.724
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.279 0.721
H30 Chorioretinal inflammation
0.000 0.281 0.719
H34.9 Retinal vascular occlusion, unspecified
0.000 0.283 0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.283 0.717
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.283 0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.283 0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.717
M08 Juvenile arthritis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M05.8 Other seropositive rheumatoid arthritis
0.000 0.283 0.717
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.283 0.717
M05.2 Rheumatoid vasculitis
0.000 0.283 0.717
M05.1 Rheumatoid lung disease
0.000 0.283 0.717
M05.0 Felty's syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
J33.1 Polypoid sinus degeneration
0.000 0.283 0.717
E78.6 Lipoprotein deficiency
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
E77 Disorders of glycoprotein metabolism
0.000 0.284 0.716
E76 Disorders of glycosaminoglycan metabolism
0.000 0.284 0.716
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.284 0.716
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.284 0.716
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.284 0.716
M07.5 Arthropathy in ulcerative colitis
0.000 0.285 0.715
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.285 0.715
M07.2 Psoriatic spondylitis
0.000 0.285 0.715
M07.1 Arthritis mutilans
0.000 0.285 0.715
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.285 0.715
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.285 0.715
I00-I02 Acute rheumatic fever
0.000 0.285 0.715
E40-E46 Malnutrition
0.000 0.285 0.715
M07.38 Other psoriatic arthropathies (Other)
0.000 0.285 0.714
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.285 0.714
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.285 0.714
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.285 0.714
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.285 0.714
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.285 0.714
L57.0 Actinic keratosis
0.000 0.285 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.286 0.714
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.287 0.713
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.287 0.713
M35.5 Multifocal fibrosclerosis
0.000 0.287 0.713
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.287 0.713
I13 Hypertensive heart and renal disease
0.000 0.287 0.713
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.288 0.712
E88.2 Lipomatosis, not elsewhere classified
0.000 0.290 0.710
L40.0 Psoriasis vulgaris
0.000 0.290 0.710
E88.8 Other specified metabolic disorders
0.000 0.291 0.709
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.291 0.709
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.707
H40.5 Glaucoma secondary to other eye disorders
0.000 0.295 0.705
L43.3 Subacute (active) lichen planus
0.000 0.295 0.705
L43.2 Lichenoid drug reaction
0.000 0.295 0.705
L43.1 Bullous lichen planus
0.000 0.295 0.705
L43.0 Hypertrophic lichen planus
0.000 0.295 0.705
I11 Hypertensive heart disease
0.000 0.296 0.704
H34.1 Central retinal artery occlusion
0.000 0.297 0.703
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.298 0.702
E70 Disorders of aromatic amino-acid metabolism
0.000 0.299 0.701
E13 Other specified diabetes mellitus
0.000 0.300 0.700
E11.6 With other specified complications
0.000 0.303 0.697
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.303 0.697
M34.8 Other forms of systemic sclerosis
0.000 0.304 0.696
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.305 0.695
H43 Disorders of vitreous body
0.000 0.307 0.693
E79 Disorders of purine and pyrimidine metabolism
0.000 0.307 0.692
H35.7 Separation of retinal layers
0.000 0.308 0.692
H33 Retinal detachments and breaks
0.000 0.310 0.690
E06.5 Other chronic thyroiditis
0.000 0.310 0.690
E06.4 Drug-induced thyroiditis
0.000 0.310 0.690
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.310 0.690
E06.1 Subacute thyroiditis
0.000 0.310 0.690
E06.0 Acute thyroiditis
0.000 0.310 0.690
M49 Spondylopathies in diseases classified elsewhere
0.000 0.316 0.684
E16.1 Other hypoglycaemia
0.000 0.318 0.682
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.318 0.682
H42 Glaucoma in diseases classified elsewhere
0.000 0.319 0.681
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.320 0.680
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.320 0.680
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.320 0.680
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.320 0.680
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.320 0.680
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.320 0.680
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.320 0.680
M34.0 Progressive systemic sclerosis
0.000 0.320 0.680
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.320 0.679
E78.4 Other hyperlipidaemia
0.000 0.321 0.678
M12 Other specific arthropathies
0.000 0.323 0.677
E07.8 Other specified disorders of thyroid
0.000 0.324 0.676
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.326 0.674
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.326 0.674
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.326 0.674
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.326 0.674
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.326 0.674
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.326 0.674
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.326 0.674
M06.38 Rheumatoid nodule (Other)
0.000 0.326 0.674
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.326 0.674
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.326 0.674
M06.33 Rheumatoid nodule (Forearm)
0.000 0.326 0.674
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.326 0.674
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.326 0.674
H34.0 Transient retinal artery occlusion
0.000 0.327 0.673
M65.2 Calcific tendinitis
0.000 0.331 0.669
M65.0 Abscess of tendon sheath
0.000 0.331 0.669
M07.6 Other enteropathic arthropathies
0.000 0.332 0.668
E84 Cystic fibrosis
0.000 0.333 0.666
M91-M94 Chondropathies
0.000 0.336 0.664
H40.6 Glaucoma secondary to drugs
0.000 0.339 0.661
H40.3 Glaucoma secondary to eye trauma
0.000 0.339 0.661
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.340 0.660
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.659
M86-M90 Other osteopathies
0.000 0.342 0.657
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.344 0.656
L10-L14 Bullous disorders
0.000 0.346 0.654
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.349 0.651
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.349 0.651
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.349 0.651
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.349 0.651
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.349 0.651
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.349 0.651
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.349 0.651
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.349 0.651
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.350 0.650
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.352 0.647
M66 Spontaneous rupture of synovium and tendon
0.000 0.354 0.646
M32 Systemic lupus erythematosus
0.000 0.355 0.644
H35.2 Other proliferative retinopathy
0.000 0.356 0.644
E88.3 Tumour lysis syndrome
0.000 0.358 0.642
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.000 0.360 0.640
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.000 0.360 0.640
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.000 0.360 0.640
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.000 0.360 0.640
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.000 0.360 0.640
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.000 0.360 0.640
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.000 0.360 0.640
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.000 0.360 0.640
E88.9 Metabolic disorder, unspecified
0.000 0.362 0.638
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.362 0.638
D62 Acute posthaemorrhagic anaemia
0.000 0.364 0.636
Chapter VIII Diseases of the ear and mastoid process
0.000 0.364 0.636
E11.4 With neurological complications
0.000 0.365 0.635
E07.1 Dyshormogenetic goitre
0.000 0.371 0.629
E07.0 Hypersecretion of calcitonin
0.000 0.371 0.629
H35.1 Retinopathy of prematurity
0.000 0.371 0.629
D50-D53 Nutritional anaemias
0.000 0.375 0.625
H40.0 Glaucoma suspect
0.000 0.378 0.622
H33.3 Retinal breaks without detachment
0.000 0.380 0.620
I15.9 Seconday hypertension, unspecified
0.000 0.381 0.619
L42 Pityriasis rosea
0.000 0.382 0.617
H43.3 Other vitreous opacities
0.000 0.383 0.617
E06.9 Thyroiditis, unspecified
0.000 0.385 0.615
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.386 0.614
H40.1 Primary open-angle glaucoma
0.000 0.387 0.613
E05.8 Other thyrotoxicosis
0.000 0.390 0.610
H60-H62 Diseases of external ear
0.000 0.392 0.608
M11 Other crystal arthropathies
0.000 0.392 0.608
I15.1 Hypertension secondary to other renal disorders
0.000 0.393 0.607
M31.6 Other giant cell arteritis
0.000 0.397 0.603
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.000 0.398 0.602
M86 Osteomyelitis
0.000 0.399 0.601
E89.4 Postprocedural ovarian failure
0.000 0.399 0.601
E73 Lactose intolerance
0.000 0.400 0.600
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.402 0.597
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.403 0.596
M15-M19 Arthrosis
0.000 0.404 0.596
M33 Dermatopolymyositis
0.000 0.406 0.594
M30.0 Polyarteritis nodosa
0.000 0.407 0.593
M60-M63 Disorders of muscles
0.000 0.407 0.592
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.407 0.592
I23 Certain current complications following acute myocardial infarction
0.000 0.408 0.592
H43.9 Disorder of vitreous body, unspecified
0.000 0.409 0.591
L55 Sunburn
0.000 0.409 0.591
M31.3 Wegener's granulomatosis
0.000 0.411 0.589
D64.4 Congenital dyserythropoietic anaemia
0.000 0.412 0.588
D64.3 Other sideroblastic anaemias
0.000 0.412 0.588
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.412 0.588
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.412 0.588
D64.0 Hereditary sideroblastic anaemia
0.000 0.412 0.588
E65-E68 Obesity and other hyperalimentation
0.000 0.413 0.587
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.413 0.587
I21 Acute myocardial infarction
0.000 0.415 0.585
M14.6 Neuropathic arthropathy
0.000 0.415 0.585
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.418 0.582
M35.0 Sicca syndrome [Sjogren]
0.000 0.423 0.577
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.423 0.576
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.426 0.574
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.426 0.574
E89.5 Postprocedural testicular hypofunction
0.000 0.426 0.574
E89.1 Postprocedural hypoinsulinaemia
0.000 0.426 0.574
E11.0 With coma
0.000 0.430 0.569
M86.9 Osteomyelitis, unspecified
0.000 0.430 0.570
I24 Other acute ischaemic heart diseases
0.000 0.431 0.569
D50 Iron deficiency anaemia
0.000 0.432 0.568
H61 Other disorders of external ear
0.000 0.433 0.567
I15.8 Other secondary hypertension
0.000 0.434 0.566
I15.2 Hypertension secondary to endocrine disorders
0.000 0.434 0.566
E78.8 Other disorders of lipoprotein metabolism
0.000 0.436 0.564
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.438 0.562
E03.1 Congenital hypothyroidism without goitre
0.000 0.438 0.561
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.440 0.560
E80.4 Gilbert's syndrome
0.000 0.440 0.560
L20-L30 Dermatitis and eczema
0.000 0.441 0.559
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.441 0.559
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.441 0.559
M30.2 Juvenile polyarteritis
0.000 0.441 0.559
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.445 0.555
D55-D59 Haemolytic anaemias
0.000 0.446 0.554
E83.8 Other disorders of mineral metabolism
0.258 0.447 0.295
E83.2 Disorders of zinc metabolism
0.258 0.447 0.295
E83.0 Disorders of copper metabolism
0.258 0.447 0.295
H33.4 Traction detachment of retina
0.000 0.447 0.553
M10 Gout
0.000 0.447 0.552
I15.0 Renovascular hypertension
0.000 0.448 0.552
M18 Arthrosis of first carpometacarpal joint
0.000 0.450 0.550
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.451 0.549
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.451 0.549
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.451 0.549
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.451 0.549
E74.2 Disorders of galactose metabolism
0.000 0.451 0.549
E74.1 Disorders of fructose metabolism
0.000 0.451 0.549
E74.0 Glycogen storage disease
0.000 0.451 0.549
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.453 0.547
E89.3 Postprocedural hypopituitarism
0.000 0.453 0.547
M31.9 Necrotising vasculopathy, unspecified
0.000 0.455 0.545
M00-M03 Infectious arthropathies
0.000 0.455 0.544
M31.1 Thrombotic microangiopathy
0.000 0.457 0.543
E83.9 Disorder of mineral metabolism, unspecified
0.280 0.459 0.261
D50.8 Other iron deficiency anaemias
0.000 0.459 0.541
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.459 0.540
L58 Radiodermatitis
0.000 0.460 0.540
L57.5 Actinic granuloma
0.000 0.461 0.539
L57.3 Poikiloderma of Civatte
0.000 0.461 0.539
L57.2 Cutis rhomboidalis nuchae
0.000 0.461 0.539
L57.1 Actinic reticuloid
0.000 0.461 0.539
G36.0 Neuromyelitis optica [Devic]
0.537 0.463 0.000
L28 Lichen simplex chronicus and prurigo
0.000 0.463 0.537
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.464 0.536
M31.8 Other specified necrotising vasculopathies
0.000 0.464 0.535
M31.7 Microscopic polyangiitis
0.000 0.464 0.535
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.464 0.535
M31.2 Lethal midline granuloma
0.000 0.464 0.535
I12.0 Hypertensive renal disease with renal failure
0.000 0.465 0.535
L80 Vitiligo
0.000 0.468 0.532
M80-M85 Disorders of bone density and structure
0.000 0.469 0.531
E89.2 Postprocedural hypoparathyroidism
0.000 0.470 0.530
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.471 0.529
H60 Otitis externa
0.000 0.475 0.525
E80.6 Other disorders of bilirubin metabolism
0.000 0.476 0.523
M46 Other inflammatory spondylopathies
0.000 0.477 0.523
H43.2 Crystalline deposits in vitreous body
0.000 0.477 0.523
E20-E35 Disorders of other endocrine glands
0.000 0.477 0.523
G36.9 Acute disseminated demyelination, unspecified
0.522 0.477 0.000
G36.8 Other specified acute disseminated demyelination
0.522 0.477 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.522 0.477 0.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.478 0.522
I00 Rheumatic fever without mention of heart involvement
0.000 0.478 0.522
M65.19 Other infective (teno)synovitis (Site unspecified)
0.000 0.478 0.522
M65.18 Other infective (teno)synovitis (Other)
0.000 0.478 0.522
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.000 0.478 0.522
M65.16 Other infective (teno)synovitis (Lower leg)
0.000 0.478 0.522
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.000 0.478 0.522
M65.13 Other infective (teno)synovitis (Forearm)
0.000 0.478 0.522
M65.12 Other infective (teno)synovitis (Upper arm)
0.000 0.478 0.522
M65.11 Other infective (teno)synovitis (Shoulder region)
0.000 0.478 0.522
M65.10 Other infective (teno)synovitis (Multiple sites)
0.000 0.478 0.522
H61.0 Perichondritis of external ear
0.000 0.478 0.522
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.479 0.521
H30.9 Chorioretinal inflammation, unspecified
0.000 0.480 0.520
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.481 0.519
M14.4 Arthropathy in amyloidosis
0.000 0.481 0.519
M14.3 Lipoid dermatoarthritis
0.000 0.481 0.519
M14.2 Diabetic arthropathy
0.000 0.481 0.519
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.481 0.519
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.481 0.519
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.483 0.517
E80.5 Crigler-Najjar syndrome
0.000 0.483 0.517
E80.3 Defects of catalase and peroxydase
0.000 0.483 0.517
E80.1 Porphyria cutanea tarda
0.000 0.483 0.517
E80.0 Hereditary erythropoietic porphyria
0.000 0.483 0.517
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.484 0.516
H30.8 Other chorioretinal inflammations
0.000 0.485 0.515
H30.2 Posterior cyclitis
0.000 0.485 0.515
H30.1 Disseminated chorioretinal inflammation
0.000 0.485 0.515
H30.0 Focal chorioretinal inflammation
0.000 0.485 0.515
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.486 0.514
M06.18 Adult-onset Still's disease (Other)
0.000 0.486 0.514
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.486 0.514
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.486 0.514
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.486 0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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