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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2508015
log Bayes Factor = 169.83
Chromosome 6   position 31,010,200  (GRCh37) Explore rs2508015 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
L40 Psoriasis
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.989 0.011 0.000
E24 Cushing's syndrome
0.972 0.028 0.000
E14.3 With ophthalmic complications
0.969 0.031 0.000
L40.0 Psoriasis vulgaris
0.000 0.043 0.957
E23 Hypofunction and other disorders of pituitary gland
0.949 0.051 0.000
K90 Intestinal malabsorption
0.933 0.067 0.000
E10.2 With renal complications
0.931 0.069 0.000
J45.9 Asthma, unspecified
0.923 0.077 0.000
E07 Other disorders of thyroid
0.920 0.080 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.911 0.089 0.000
E23.2 Diabetes insipidus
0.910 0.090 0.000
E10.1 With ketoacidosis
0.904 0.096 0.000
E10.0 With coma
0.903 0.097 0.000
E10.4 With neurological complications
0.893 0.107 0.000
K90.9 Intestinal malabsorption, unspecified
0.882 0.118 0.000
E24.2 Drug-induced Cushing's syndrome
0.881 0.119 0.000
E24.9 Cushing's syndrome, unspecified
0.879 0.121 0.000
E28 Ovarian dysfunction
0.866 0.134 0.000
E03.8 Other specified hypothyroidism
0.864 0.136 0.000
E07.9 Disorder of thyroid, unspecified
0.852 0.148 0.000
E16 Other disorders of pancreatic internal secretion
0.847 0.153 0.000
E27 Other disorders of adrenal gland
0.845 0.155 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.840 0.160 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.822 0.178 0.000
E23.6 Other disorders of pituitary gland
0.822 0.178 0.000
L40.8 Other psoriasis
0.000 0.188 0.812
E14.6 With other specified complications
0.808 0.192 0.000
E24.0 Pituitary-dependent Cushing's disease
0.805 0.195 0.000
E10.6 With other specified complications
0.803 0.197 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.794 0.206 0.000
E14.1 With ketoacidosis
0.793 0.207 0.000
K90.8 Other intestinal malabsorption
0.791 0.209 0.000
E27.1 Primary adrenocortical insufficiency
0.778 0.222 0.000
E31 Polyglandular dysfunction
0.767 0.233 0.000
E20 Hypoparathyroidism
0.759 0.241 0.000
E14.2 Withrenal complications
0.750 0.250 0.000
E14.8 With unspecified complications
0.749 0.250 0.000
E21.3 Hyperparathyroidism, unspecified
0.746 0.254 0.000
E16.2 Hypoglycaemia, unspecified
0.746 0.254 0.000
E10.5 With peripheral circulatory complications
0.739 0.261 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.262 0.738
E14.0 With coma
0.737 0.263 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.735 0.265 0.000
M35.0 Sicca syndrome [Sjogren]
0.734 0.266 0.000
E28.3 Primary ovarian failure
0.727 0.273 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.724 0.276 0.000
E10.8 With unspecified complications
0.719 0.281 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
E22 Hyperfunction of pituitary gland
0.714 0.286 0.000
E24.8 Other Cushing's syndrome
0.712 0.288 0.000
E14.7 With multiple complications
0.709 0.291 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.708 0.292 0.000
E14.5 With peripheral circulatory complications
0.707 0.292 0.000
E05.8 Other thyrotoxicosis
0.706 0.293 0.000
E23.7 Disorder of pituitary gland, unspecified
0.704 0.296 0.000
E10.7 With multiple complications
0.703 0.297 0.000
E07.8 Other specified disorders of thyroid
0.701 0.299 0.000
E28.2 Polycystic ovarian syndrome
0.699 0.301 0.000
E40-E46 Malnutrition
0.699 0.301 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.697 0.303 0.000
E24.3 Ectopic ACTH syndrome
0.697 0.303 0.000
E24.1 Nelson's syndrome
0.697 0.303 0.000
E14.9 Without complications
0.697 0.303 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.695 0.305 0.000
L40.1 Generalised pustular psoriasis
0.000 0.315 0.685
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.680 0.319 0.000
E23.1 Drug-induced hypopituitarism
0.680 0.319 0.000
K90.3 Pancreatic steatorrhoea
0.669 0.331 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.669 0.331 0.000
K90.1 Tropical sprue
0.669 0.331 0.000
E13 Other specified diabetes mellitus
0.668 0.332 0.000
E07.1 Dyshormogenetic goitre
0.660 0.340 0.000
E07.0 Hypersecretion of calcitonin
0.660 0.340 0.000
E14.4 With neurological complications
0.654 0.346 0.000
E15 Nondiabetic hypoglycaemic coma
0.653 0.347 0.000
E29 Testicular dysfunction
0.652 0.348 0.000
E27.9 Disorder of adrenal gland, unspecified
0.651 0.349 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.645 0.354 0.000
E06 Thyroiditis
0.645 0.355 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.641 0.359 0.000
E03.1 Congenital hypothyroidism without goitre
0.634 0.366 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.621 0.378 0.000
E28.9 Ovarian dysfunction, unspecified
0.621 0.379 0.000
E28.8 Other ovarian dysfunction
0.621 0.379 0.000
E28.1 Androgen excess
0.621 0.379 0.000
E28.0 Oestrogen excess
0.621 0.379 0.000
E16.1 Other hypoglycaemia
0.617 0.383 0.000
E25 Adrenogenital disorders
0.612 0.387 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.607 0.392 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.607 0.392 0.000
E16.4 Abnormal secretion of gastrin
0.607 0.392 0.000
E16.3 Increased secretion of glucagon
0.607 0.392 0.000
E27.5 Adrenomedullary hyperfunction
0.606 0.394 0.000
E27.0 Other adrenocortical overactivity
0.606 0.394 0.000
E31.0 Autoimmune polyglandular failure
0.602 0.398 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.594 0.406 0.000
E20.9 Hypoparathyroidism, unspecified
0.589 0.411 0.000
E26 Hyperaldosteronism
0.576 0.424 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.564 0.435 0.000
E21.2 Other hyperparathyroidism
0.561 0.439 0.000
E21.4 Other specified disorders of parathyroid gland
0.556 0.444 0.000
E27.2 Addisonian crisis
0.555 0.445 0.000
E31.9 Polyglandular dysfunction, unspecified
0.550 0.450 0.000
E31.8 Other polyglandular dysfunction
0.550 0.450 0.000
E31.1 Polyglandular hyperfunction
0.550 0.450 0.000
E20.8 Other hypoparathyroidism
0.544 0.455 0.000
E20.1 Pseudohypoparathyroidism
0.544 0.455 0.000
E20.0 Idiopathic hypoparathyroidism
0.544 0.455 0.000
E13.3 With ophthalmic complications
0.516 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.512 0.488 0.000
E30.8 Other disorders of puberty
0.512 0.488 0.000
E30.1 Precocious puberty
0.512 0.488 0.000
E30.0 Delayed puberty
0.512 0.488 0.000
E32.9 Disease of thymus, unspecified
0.512 0.488 0.000
E32.8 Other diseases of thymus
0.512 0.488 0.000
E32.1 Abscess of thymus
0.512 0.488 0.000
E32.0 Persistent hyperplasia of thymus
0.512 0.488 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.512 0.488 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.512 0.488 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.512 0.488 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.512 0.488 0.000
E22.8 Other hyperfunction of pituitary gland
0.512 0.488 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.501 0.499 0.000
E45 Retarded development following protein-energy malnutrition
0.501 0.499 0.000
E43 Unspecified severe protein-energy malnutrition
0.501 0.499 0.000
E42 Marasmic kwashiorkor
0.501 0.499 0.000
E41 Nutritional marasmus
0.501 0.499 0.000
E40 Kwashiorkor
0.501 0.499 0.000
E22.1 Hyperprolactinaemia
0.490 0.510 0.000
E46 Unspecified protein-energy malnutrition
0.483 0.517 0.000
E06.5 Other chronic thyroiditis
0.481 0.519 0.000
E13.8 With unspecified complications
0.479 0.521 0.000
E13.7 With multiple complications
0.479 0.521 0.000
E13.6 With other specified complications
0.479 0.521 0.000
E13.5 With peripheral circulatory complications
0.479 0.521 0.000
E13.4 With neurological complications
0.479 0.521 0.000
E13.2 With renal complications
0.479 0.521 0.000
E13.1 With ketoacidosis
0.479 0.521 0.000
E13.0 With coma
0.479 0.521 0.000
E29.9 Testicular dysfunction, unspecified
0.467 0.533 0.000
E29.8 Other testicular dysfunction
0.467 0.533 0.000
E29.0 Testicular hyperfunction
0.467 0.533 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.464 0.535 0.000
E06.4 Drug-induced thyroiditis
0.462 0.537 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.462 0.537 0.000
E06.1 Subacute thyroiditis
0.462 0.537 0.000
E06.0 Acute thyroiditis
0.462 0.537 0.000
E06.3 Autoimmune thyroiditis
0.447 0.553 0.000
E25.9 Adrenogenital disorder, unspecified
0.439 0.561 0.000
E25.8 Other adrenogenital disorders
0.439 0.561 0.000
E23.0 Hypopituitarism
0.419 0.581 0.000
E26.9 Hyperaldosteronism, unspecified
0.413 0.586 0.000
E26.8 Other hyperaldosteronism
0.413 0.587 0.000
E26.1 Secondary hyperaldosteronism
0.413 0.587 0.000
E29.1 Testicular hypofunction
0.405 0.595 0.000
E27.8 Other specified disorders of adrenal gland
0.392 0.607 0.000
E06.9 Thyroiditis, unspecified
0.384 0.616 0.000
E13.9 Without complications
0.372 0.628 0.000
E44.1 Mild protein-energy malnutrition
0.359 0.640 0.000
E44.0 Moderate protein-energy malnutrition
0.359 0.640 0.000
J45 Asthma
0.357 0.643 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.337 0.662 0.001
E50-E64 Other nutritional deficiencies
0.330 0.670 0.000
E21.0 Primary hyperparathyroidism
0.329 0.671 0.000
E34 Other endocrine disorders
0.316 0.683 0.001
E22.0 Acromegaly and pituitary gigantism
0.314 0.686 0.000
C61 Malignant neoplasm of prostate
0.000 0.689 0.311
E26.0 Primary hyperaldosteronism
0.273 0.726 0.001
E51 Thiamine deficiency
0.273 0.727 0.000
J45.1 Nonallergic asthma
0.272 0.728 0.000
J45.8 Mixed asthma
0.259 0.741 0.000
E65-E68 Obesity and other hyperalimentation
0.237 0.760 0.003
E64 Sequelae of malnutrition and other nutritional deficiencies
0.236 0.763 0.000
E63 Other nutritional deficiencies
0.236 0.763 0.000
E50 Vitamin A deficiency
0.236 0.763 0.000
E60 Dietary zinc deficiency
0.236 0.763 0.000
E59 Dietary selenium deficiency
0.236 0.763 0.000
E54 Ascorbic acid deficiency
0.236 0.763 0.000
E52 Niacin deficiency [pellagra]
0.236 0.763 0.000
E51.2 Wernicke's encephalopathy
0.233 0.767 0.000
E34.5 Androgen resistance syndrome
0.226 0.772 0.001
E34.4 Constitutional tall stature
0.226 0.772 0.001
E34.3 Short stature, not elsewhere classified
0.226 0.772 0.001
E34.2 Ectopic hormone secretion, not elsewhere classified
0.226 0.772 0.001
E34.1 Other hypersecretion of intestinal hormones
0.226 0.772 0.001
E56 Other vitamin deficiencies
0.223 0.777 0.000
E58 Dietary calcium deficiency
0.221 0.779 0.000
J45.0 Predominantly allergic asthma
0.217 0.783 0.000
L40-L45 Papulosquamous disorders
0.000 0.798 0.202
E51.9 Thiamine deficiency, unspecified
0.196 0.804 0.000
E51.8 Other manifestations of thiamine deficiency
0.196 0.804 0.000
E51.1 Beriberi
0.196 0.804 0.000
E34.8 Other specified endocrine disorders
0.192 0.806 0.001
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.819 0.181
E61 Deficiency of other nutrient elements
0.175 0.824 0.000
E67 Other hyperalimentation
0.170 0.828 0.002
E68 Sequelae of hyperalimentation
0.170 0.828 0.002
K50 Crohn's disease [regional enteritis]
0.000 0.828 0.172
K50.1 Crohn's disease of large intestine
0.000 0.828 0.172
K50.0 Crohn's disease of small intestine
0.000 0.829 0.171
E50.9 Vitamin A deficiency, unspecified
0.170 0.830 0.000
E50.8 Other manifestations of vitamin A deficiency
0.170 0.830 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.170 0.830 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.170 0.830 0.000
E50.5 Vitamin A deficiency with night blindness
0.170 0.830 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.170 0.830 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.170 0.830 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.170 0.830 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.170 0.830 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.170 0.830 0.000
E63.9 Nutritional deficiency, unspecified
0.170 0.830 0.000
E63.8 Other specified nutritional deficiencies
0.170 0.830 0.000
E63.1 Imbalance of constituents of food intake
0.170 0.830 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.170 0.830 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.170 0.830 0.000
E64.8 Sequelae of other nutritional deficiencies
0.170 0.830 0.000
E64.3 Sequelae of rickets
0.170 0.830 0.000
E64.2 Sequelae of vitamin C deficiency
0.170 0.830 0.000
E64.1 Sequelae of vitamin A deficiency
0.170 0.830 0.000
E64.0 Sequelae of protein-energy malnutrition
0.170 0.830 0.000
E34.0 Carcinoid syndrome
0.165 0.833 0.001
M35 Other systemic involvement of connective tissue
0.163 0.837 0.000
R31 Unspecified haematuria
0.000 0.839 0.161
E55 Vitamin D deficiency
0.161 0.839 0.000
K50.8 Other Crohn's disease
0.000 0.839 0.161
E56.9 Vitamin deficiency, unspecified
0.160 0.840 0.000
E56.8 Deficiency of other vitamins
0.160 0.840 0.000
E56.0 Deficiency of vitamin E
0.160 0.840 0.000
E56.1 Deficiency of vitamin K
0.146 0.853 0.000
L44 Other papulosquamous disorders
0.000 0.854 0.146
L41 Parapsoriasis
0.000 0.855 0.145
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.855 0.145
K50.9 Crohn's disease, unspecified
0.000 0.868 0.132
E53 Deficiency of other B group vitamins
0.132 0.868 0.000
M35.1 Other overlap syndromes
0.128 0.872 0.000
E61.9 Deficiency of nutrient element, unspecified
0.126 0.874 0.000
E61.8 Deficiency of other specified nutrient elements
0.126 0.874 0.000
E61.7 Deficiency of multiple nutrient elements
0.126 0.874 0.000
E61.6 Vanadium deficiency
0.126 0.874 0.000
E61.5 Molybdenum deficiency
0.126 0.874 0.000
E61.4 Chromium deficiency
0.126 0.874 0.000
E61.3 Manganese deficiency
0.126 0.874 0.000
E61.0 Copper deficiency
0.126 0.874 0.000
E61.2 Magnesium deficiency
0.124 0.876 0.000
E67.8 Other specified hyperalimentation
0.122 0.876 0.002
E67.3 Hypervitaminosis D
0.122 0.876 0.002
E67.2 Megavitamin-B6 syndrome
0.122 0.876 0.002
E67.1 Hypercarotenaemia
0.122 0.876 0.002
E67.0 Hypervitaminosis A
0.122 0.876 0.002
L42 Pityriasis rosea
0.000 0.877 0.123
M35.8 Other specified systemic involvement of connective tissue
0.119 0.881 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.117 0.883 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.117 0.883 0.000
M35.5 Multifocal fibrosclerosis
0.117 0.883 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.117 0.883 0.000
E55.0 Rickets, active
0.115 0.885 0.000
E34.9 Endocrine disorder, unspecified
0.106 0.892 0.002
M35.2 Behcet's disease
0.106 0.893 0.000
M35.7 Hypermobility syndrome
0.106 0.894 0.000
L44.0 Pityriasis rubra pilaris
0.000 0.894 0.105
L44.9 Papulosquamous disorder, unspecified
0.000 0.895 0.105
L44.8 Other specified papulosquamous disorders
0.000 0.895 0.105
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.895 0.105
L44.3 Lichen ruber moniliformis
0.000 0.895 0.105
L44.2 Lichen striatus
0.000 0.895 0.105
L44.1 Lichen nitidus
0.000 0.895 0.105
L41.9 Parapsoriasis, unspecified
0.000 0.896 0.104
L41.8 Other parapsoriasis
0.000 0.896 0.104
L41.5 Retiform parapsoriasis
0.000 0.896 0.104
L41.4 Large plaque parapsoriasis
0.000 0.896 0.104
L41.3 Small plaque parapsoriasis
0.000 0.896 0.104
L41.2 Lymphomatoid papulosis
0.000 0.896 0.104
L41.1 Pityriasis lichenoides chronica
0.000 0.896 0.104
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.896 0.104
H00.1 Chalazion
0.000 0.905 0.095
E53.1 Pyridoxine deficiency
0.094 0.905 0.000
E53.0 Riboflavin deficiency
0.094 0.905 0.000
M45 Ankylosing spondylitis
0.000 0.910 0.090
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.084 0.916 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.917 0.083
L43 Lichen planus
0.000 0.919 0.081
E65 Localised adiposity
0.075 0.922 0.003
E53.9 Vitamin B deficiency, unspecified
0.071 0.929 0.000
C60-C63 Malignant neoplasms of male genital organs
0.000 0.929 0.071
E61.1 Iron deficiency
0.069 0.931 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.935 0.065
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.935 0.065
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.935 0.065
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.935 0.065
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.935 0.065
M35.3 Polymyalgia rheumatica
0.062 0.938 0.000
E70-E90 Metabolic disorders
0.061 0.939 0.000
E89.0 Postprocedural hypothyroidism
0.061 0.939 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.061 0.939 0.000
K90-K93 Other diseases of the digestive system
0.059 0.941 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.941 0.059
L43.3 Subacute (active) lichen planus
0.000 0.942 0.058
L43.2 Lichenoid drug reaction
0.000 0.942 0.058
L43.1 Bullous lichen planus
0.000 0.942 0.058
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.942 0.058
L43.8 Other lichen planus
0.000 0.943 0.057
E73 Lactose intolerance
0.056 0.944 0.000
E73.9 Lactose intolerance, unspecified
0.053 0.947 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.947 0.053
E04 Other non-toxic goitre
0.052 0.948 0.001
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.948 0.052
C63 Malignant neoplasm of other and unspecified male genital organs
0.000 0.949 0.051
L43.0 Hypertrophic lichen planus
0.000 0.949 0.051
E74 Other disorders of carbohydrate metabolism
0.049 0.951 0.000
H00 Hordeolum and chalazion
0.000 0.953 0.047
E89.3 Postprocedural hypopituitarism
0.047 0.953 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.046 0.954 0.000
E89.5 Postprocedural testicular hypofunction
0.045 0.954 0.000
E53.8 Deficiency of other specified B group vitamins
0.044 0.956 0.000
E77 Disorders of glycoprotein metabolism
0.044 0.956 0.000
E76 Disorders of glycosaminoglycan metabolism
0.044 0.956 0.000
E72 Other disorders of amino-acid metabolism
0.044 0.956 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.044 0.956 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.044 0.956 0.000
E89.4 Postprocedural ovarian failure
0.044 0.956 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.044 0.956 0.000
E89.1 Postprocedural hypoinsulinaemia
0.044 0.956 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.957 0.043
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.043 0.957 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.043 0.957 0.000
C60 Malignant neoplasm of penis
0.000 0.957 0.042
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.042 0.958 0.000
E70 Disorders of aromatic amino-acid metabolism
0.041 0.959 0.000
E73.8 Other lactose intolerance
0.041 0.959 0.000
E73.1 Secondary lactase deficiency
0.041 0.959 0.000
E73.0 Congenital lactase deficiency
0.041 0.959 0.000
E84 Cystic fibrosis
0.040 0.960 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.040 0.960 0.000
E55.9 Vitamin D deficiency, unspecified
0.039 0.961 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.961 0.039
Q21.1 Atrial septal defect
0.000 0.961 0.039
K50-K52 Noninfective enteritis and colitis
0.000 0.962 0.038
E04.8 Other specified non-toxic goitre
0.037 0.962 0.001
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.962 0.038
E79 Disorders of purine and pyrimidine metabolism
0.037 0.963 0.000
K40 Inguinal hernia
0.000 0.963 0.037
C62 Malignant neoplasm of testis
0.000 0.963 0.037
C63.9 Male genital organ, unspecified
0.000 0.963 0.037
C63.8 Overlapping lesion of male genital organs
0.000 0.963 0.037
C63.7 Other specified male genital organs
0.000 0.963 0.037
C63.2 Scrotum
0.000 0.963 0.037
C63.1 Spermatic cord
0.000 0.963 0.037
C63.0 Epididymis
0.000 0.963 0.037
E88 Other metabolic disorders
0.037 0.963 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.036 0.964 0.000
E89.2 Postprocedural hypoparathyroidism
0.035 0.965 0.000
M07.3 Other psoriatic arthropathies
0.000 0.965 0.035
E74.9 Disorder of carbohydrate metabolism, unspecified
0.035 0.965 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.035 0.965 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.035 0.965 0.000
E74.2 Disorders of galactose metabolism
0.035 0.965 0.000
E74.1 Disorders of fructose metabolism
0.035 0.965 0.000
E74.0 Glycogen storage disease
0.035 0.965 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.965 0.035
D64.9 Anaemia, unspecified
0.033 0.967 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.967 0.033
E88.2 Lipomatosis, not elsewhere classified
0.032 0.967 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.968 0.032
E80 Disorders of porphyrin and bilirubin metabolism
0.032 0.968 0.000
E71.3 Disorders of fatty-acid metabolism
0.032 0.968 0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.032 0.968 0.000
E71.1 Other disorders of branched-chain amino-acid metabolism
0.032 0.968 0.000
E71.0 Maple-syrup-urine disease
0.032 0.968 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.032 0.968 0.000
E72.8 Other specified disorders of amino-acid metabolism
0.032 0.968 0.000
E72.5 Disorders of glycine metabolism
0.032 0.968 0.000
E72.4 Disorders of ornithine metabolism
0.032 0.968 0.000
E72.3 Disorders of lysine and hydroxylysine metabolism
0.032 0.968 0.000
E72.2 Disorders of urea cycle metabolism
0.032 0.968 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.032 0.968 0.000
E72.0 Disorders of amino-acid transport
0.032 0.968 0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.032 0.968 0.000
E76.8 Other disorders of glucosaminoglycan metabolism
0.032 0.968 0.000
E76.3 Mucopolysaccharidosis, unspecified
0.032 0.968 0.000
E76.2 Other mucopolysaccharidoses
0.032 0.968 0.000
E76.1 Mucopolysaccharidosis, type II
0.032 0.968 0.000
E76.0 Mucopolysaccharidosis, type I
0.032 0.968 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.032 0.968 0.000
E77.8 Other disorders of glycoprotein metabolism
0.032 0.968 0.000
E77.1 Defects in glycoprotein degradation
0.032 0.968 0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.032 0.968 0.000
M06.9 Rheumatoid arthritis, unspecified
0.031 0.969 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.031 0.969 0.000
K93.1 Megacolon in Chagas' disease
0.031 0.969 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.031 0.969 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.031 0.969 0.000
C60.8 Overlapping lesion of penis
0.000 0.969 0.030
C60.2 Body of penis
0.000 0.969 0.030
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.970 0.030
E75.6 Lipid storage disorder, unspecified
0.030 0.970 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.030 0.970 0.000
E75.3 Sphingolipidosis, unspecified
0.030 0.970 0.000
E75.2 Other sphingolipidosis
0.030 0.970 0.000
E75.1 Other gangliosidosis
0.030 0.970 0.000
E75.0 GM2 gangliosidosis
0.030 0.970 0.000
I83 Varicose veins of lower extremities
0.000 0.970 0.030
C60.1 Glans penis
0.000 0.970 0.030
C60.0 Prepuce
0.000 0.970 0.030
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.029 0.970 0.000
E70.8 Other disorders of aromatic amino-acid metabolism
0.029 0.970 0.000
E70.2 Disorders of tyrosine metabolism
0.029 0.970 0.000
E70.1 Other hyperphenylalaninaemias
0.029 0.970 0.000
E70.0 Classical phenylketonuria
0.029 0.970 0.000
E04.0 Non-toxic diffuse goitre
0.029 0.970 0.001
E88.8 Other specified metabolic disorders
0.029 0.971 0.000
E84.8 Cystic fibrosis with other manifestations
0.029 0.971 0.000
E84.1 Cystic fibrosis with intestinal manifestations
0.029 0.971 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.029 0.971 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.028 0.971 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.971 0.028
E75.5 Other lipid storage disorders
0.028 0.972 0.000
N05.2 Diffuse membranous glomerulonephritis
0.028 0.972 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.972 0.028
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.972 0.028
C62.1 Descended testis
0.000 0.972 0.027
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.027 0.973 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.027 0.973 0.000
E79.1 Lesch-Nyhan syndrome
0.027 0.973 0.000
N05 Unspecified nephritic syndrome
0.027 0.973 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.973 0.027
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.973 0.027
E70.3 Albinism
0.026 0.973 0.000
C62.0 Undescended testis
0.000 0.973 0.027
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.027 0.973 0.000
K52 Other non-infective gastro-enteritis and colitis
0.000 0.974 0.026
E80.2 Other porphyria
0.025 0.974 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.026 0.974 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.974 0.025
M07.38 Other psoriatic arthropathies (Other)
0.000 0.975 0.025
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.975 0.025
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.975 0.025
N05.9 Unspecified
0.025 0.975 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.975 0.025
E84.9 Cystic fibrosis, unspecified
0.024 0.975 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.024 0.976 0.000
C60.9 Penis, unspecified
0.000 0.976 0.024
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.976 0.024
E80.7 Disorder of bilirubin metabolism, unspecified
0.024 0.976 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.023 0.976 0.000
Q21 Congenital malformations of cardiac septa
0.000 0.977 0.023
E80.5 Crigler-Najjar syndrome
0.023 0.977 0.000
E80.3 Defects of catalase and peroxydase
0.023 0.977 0.000
E80.0 Hereditary erythropoietic porphyria
0.023 0.977 0.000
K75.4 Autoimmune hepatitis
0.023 0.977 0.000
E88.9 Metabolic disorder, unspecified
0.022 0.978 0.000
N40 Hyperplasia of prostate
0.000 0.978 0.022
E80.1 Porphyria cutanea tarda
0.022 0.978 0.000
E88.3 Tumour lysis syndrome
0.022 0.978 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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