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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4947350
log Bayes Factor = 137.219
Chromosome 6   position 32,767,620  (GRCh37) Explore rs4947350 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
0.999 0.001 0.000
E10.4 With neurological complications
0.999 0.001 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.999 0.001 0.000
E10.2 With renal complications
0.999 0.001 0.000
E14.3 With ophthalmic complications
0.999 0.001 0.000
E27.1 Primary adrenocortical insufficiency
0.998 0.002 0.000
E27 Other disorders of adrenal gland
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.997 0.003 0.000
R31 Unspecified haematuria
0.000 0.004 0.996
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
D61 Other aplastic anaemias
0.995 0.005 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.994 0.006 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.006 0.994
B25-B34 Other viral diseases
0.993 0.007 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.993 0.007 0.000
K50.9 Crohn's disease, unspecified
0.000 0.007 0.993
N17-N19 Renal failure
0.992 0.008 0.000
N04 Nephrotic syndrome
0.991 0.009 0.000
D69 Purpura and other haemorrhagic conditions
0.991 0.009 0.000
D50 Iron deficiency anaemia
0.990 0.010 0.000
D61.9 Aplastic anaemia, unspecified
0.989 0.011 0.000
D50.9 Iron deficiency anaemia, unspecified
0.988 0.012 0.000
B25 Cytomegaloviral disease
0.987 0.013 0.000
N18 Chronic renal failure
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.984 0.016 0.000
D80-D89 Certain disorders involving the immune mechanism
0.984 0.016 0.000
D51 Vitamin B12 deficiency anaemia
0.984 0.016 0.000
K50-K52 Noninfective enteritis and colitis
0.008 0.018 0.974
N04.9 Unspecified
0.982 0.018 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.981 0.019 0.000
B25.9 Cytomegaloviral disease, unspecified
0.981 0.019 0.000
D69.6 Thrombocytopenia, unspecified
0.977 0.023 0.000
K51 Ulcerative colitis
0.000 0.025 0.974
Q38-Q45 Other congenital malformations of the digestive system
0.972 0.028 0.000
K50.8 Other Crohn's disease
0.000 0.029 0.971
M60-M63 Disorders of muscles
0.971 0.029 0.000
G56 Mononeuropathies of upper limb
0.965 0.035 0.000
M34 Systemic sclerosis
0.964 0.036 0.000
N05 Unspecified nephritic syndrome
0.963 0.037 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.962 0.038 0.000
G56.0 Carpal tunnel syndrome
0.962 0.038 0.000
E10.5 With peripheral circulatory complications
0.960 0.040 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.040 0.960
N18.9 Chronic renal failure, unspecified
0.955 0.045 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.954 0.046 0.000
N17 Acute renal failure
0.953 0.047 0.000
N18.0 End-stage renal disease
0.953 0.047 0.000
I74 Arterial embolism and thrombosis
0.951 0.049 0.000
I73 Other peripheral vascular diseases
0.949 0.051 0.000
D86 Sarcoidosis
0.947 0.053 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.943 0.057 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.943 0.057 0.000
I73.0 Raynaud's syndrome
0.940 0.060 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.940 0.060 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.938 0.062 0.000
K51.4 Pseudopolyposis of colon
0.000 0.063 0.937
E11 Non-insulin-dependent diabetes mellitus
0.936 0.064 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.929 0.071 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.926 0.074 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.926 0.074 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.924 0.076 0.000
E11.3 With ophthalmic complications
0.924 0.076 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.923 0.077 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.923 0.077 0.000
J44 Other chronic obstructive pulmonary disease
0.922 0.078 0.000
A63.0 Anogenital (venereal) warts
0.922 0.078 0.000
H35 Other retinal disorders
0.921 0.079 0.000
Chapter IX Diseases of the circulatory system
0.920 0.080 0.000
M62 Other disorders of muscle
0.919 0.081 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.919 0.081 0.000
H33 Retinal detachments and breaks
0.917 0.083 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.917 0.083 0.000
G30-G32 Other degenerative diseases of the nervous system
0.915 0.085 0.000
C91 Lymphoid leukaemia
0.914 0.086 0.000
E10.0 With coma
0.913 0.087 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.913 0.087 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.912 0.088 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.912 0.088 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.910 0.090 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.909 0.091 0.000
J40-J47 Chronic lower respiratory diseases
0.908 0.092 0.000
Chapter X Diseases of the respiratory system
0.904 0.096 0.000
M21 Other acquired deformities of limbs
0.903 0.097 0.000
M32 Systemic lupus erythematosus
0.901 0.099 0.000
N17.9 Acute renal failure, unspecified
0.901 0.099 0.000
E07 Other disorders of thyroid
0.897 0.103 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.895 0.105 0.000
H33.3 Retinal breaks without detachment
0.895 0.105 0.000
D86.9 Sarcoidosis, unspecified
0.894 0.106 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.893 0.107 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.891 0.109 0.000
K50.1 Crohn's disease of large intestine
0.000 0.109 0.891
E89.0 Postprocedural hypothyroidism
0.889 0.111 0.000
E70-E90 Metabolic disorders
0.888 0.112 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.887 0.113 0.000
G59.0 Diabetic mononeuropathy
0.887 0.113 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.113 0.886
D69.4 Other primary thrombocytopenia
0.886 0.113 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.117 0.883
E50-E64 Other nutritional deficiencies
0.882 0.118 0.000
M80-M85 Disorders of bone density and structure
0.880 0.120 0.000
T39.1 4-Aminophenol derivatives
0.000 0.120 0.880
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.122 0.878
Q43 Other congenital malformations of intestine
0.878 0.122 0.000
C91.1 Chronic lymphocytic leukaemia
0.874 0.126 0.000
D52 Folate deficiency anaemia
0.871 0.128 0.000
K50.0 Crohn's disease of small intestine
0.000 0.130 0.870
Chapter XII Diseases of the skin and subcutaneous tissue
0.869 0.131 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.132 0.868
H10-H13 Disorders of conjunctiva
0.867 0.133 0.000
E24 Cushing's syndrome
0.866 0.134 0.000
B07 Viral warts
0.866 0.134 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.865 0.135 0.000
H35.2 Other proliferative retinopathy
0.864 0.136 0.000
E11.2 With renal complications
0.864 0.136 0.000
N18.2 Chronic kidney disease, stage 2
0.864 0.136 0.000
H31 Other disorders of choroid
0.863 0.137 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.138 0.862
M60 Myositis
0.861 0.139 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.858 0.142 0.000
M05-M14 Inflammatory polyarthropathies
0.857 0.143 0.000
N25-N29 Other disorders of kidney and ureter
0.856 0.143 0.000
A80-A89 Viral infections of the central nervous system
0.856 0.144 0.000
C81 Hodgkin's disease
0.855 0.145 0.000
Q44.6 Cystic disease of liver
0.855 0.145 0.000
N05.2 Diffuse membranous glomerulonephritis
0.855 0.145 0.000
B15-B19 Viral hepatitis
0.850 0.150 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.151 0.849
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.848 0.152 0.000
K51.5 Mucosal proctocolitis
0.000 0.153 0.847
G51 Facial nerve disorders
0.846 0.154 0.000
N03 Chronic nephritic syndrome
0.846 0.154 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.846 0.154 0.000
I63 Cerebral infarction
0.845 0.155 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.845 0.155 0.000
B34 Viral infection of unspecified site
0.843 0.157 0.000
M62.8 Other specified disorders of muscle
0.843 0.157 0.000
C83.3 Large cell (diffuse)
0.841 0.159 0.000
J90-J94 Other diseases of pleura
0.840 0.160 0.000
D55-D59 Haemolytic anaemias
0.839 0.161 0.000
H30 Chorioretinal inflammation
0.839 0.161 0.000
E10.8 With unspecified complications
0.838 0.162 0.000
H35.4 Peripheral retinal degeneration
0.837 0.163 0.000
I60-I69 Cerebrovascular diseases
0.837 0.163 0.000
I73.9 Peripheral vascular disease, unspecified
0.836 0.164 0.000
G54 Nerve root and plexus disorders
0.835 0.165 0.000
E14.8 With unspecified complications
0.834 0.166 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.167 0.833
L20-L30 Dermatitis and eczema
0.833 0.167 0.000
E28 Ovarian dysfunction
0.832 0.168 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.830 0.170 0.000
D86.3 Sarcoidosis of skin
0.828 0.172 0.000
D61.1 Drug-induced aplastic anaemia
0.828 0.172 0.000
E10.7 With multiple complications
0.827 0.173 0.000
M34.0 Progressive systemic sclerosis
0.827 0.173 0.000
E10.6 With other specified complications
0.827 0.173 0.000
J90 Pleural effusion, not elsewhere classified
0.827 0.173 0.000
N05.1 Focal and segmental glomerular lesions
0.826 0.174 0.000
K75.4 Autoimmune hepatitis
0.825 0.175 0.000
M34.9 Systemic sclerosis, unspecified
0.825 0.175 0.000
M34.8 Other forms of systemic sclerosis
0.825 0.175 0.000
C88 Malignant immunoproliferative diseases
0.825 0.175 0.000
E14.2 Withrenal complications
0.824 0.176 0.000
M82 Osteoporosis in diseases classified elsewhere
0.823 0.177 0.000
E23 Hypofunction and other disorders of pituitary gland
0.823 0.177 0.000
E07.8 Other specified disorders of thyroid
0.819 0.181 0.000
K75 Other inflammatory liver diseases
0.819 0.181 0.000
M24 Other specific joint derangements
0.818 0.182 0.000
I63.8 Other cerebral infarction
0.818 0.182 0.000
G70-G73 Diseases of myoneural junction and muscle
0.818 0.182 0.000
L10-L14 Bullous disorders
0.816 0.184 0.000
E22 Hyperfunction of pituitary gland
0.815 0.185 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.186 0.814
M22 Disorders of patella
0.814 0.186 0.000
M23 Internal derangement of knee
0.812 0.188 0.000
E53 Deficiency of other B group vitamins
0.811 0.189 0.000
L27 Dermatitis due to substances taken internally
0.811 0.189 0.000
N17.0 Acute renal failure with tubular necrosis
0.811 0.189 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.810 0.190 0.000
M86-M90 Other osteopathies
0.810 0.190 0.000
G52 Disorders of other cranial nerves
0.809 0.191 0.000
M06 Other rheumatoid arthritis
0.809 0.191 0.000
D53 Other nutritional anaemias
0.809 0.191 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.808 0.192 0.000
D73 Diseases of spleen
0.807 0.193 0.000
J47 Bronchiectasis
0.807 0.193 0.000
M21.0 Valgus deformity, not elsewhere classified
0.806 0.194 0.000
T43.2 Other and unspecified antidepressants
0.000 0.195 0.805
E40-E46 Malnutrition
0.805 0.195 0.000
C91.9 Lymphoid leukaemia, unspecified
0.801 0.199 0.000
K70-K77 Diseases of liver
0.801 0.199 0.000
B25.8 Other cytomegaloviral diseases
0.801 0.199 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.800 0.200 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.799 0.201 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.797 0.203 0.000
Q65 Congenital deformities of hip
0.797 0.203 0.000
G56.4 Causalgia
0.795 0.205 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.793 0.207 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.788 0.212 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.788 0.212 0.000
N18.5 Chronic kidney disease, stage 5
0.787 0.213 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.213 0.787
G30 Alzheimer's disease
0.786 0.214 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.214 0.786
H35.0 Background retinopathy and retinal vascular changes
0.785 0.215 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.785 0.215 0.000
E13 Other specified diabetes mellitus
0.784 0.216 0.000
A15-A19 Tuberculosis
0.783 0.217 0.000
M06.9 Rheumatoid arthritis, unspecified
0.783 0.217 0.000
G00 Bacterial meningitis, not elsewhere classified
0.783 0.217 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.782 0.218 0.000
M82.1 Osteoporosis in endocrine disorders
0.782 0.218 0.000
K72 Hepatic failure, not elsewhere classified
0.780 0.220 0.000
D52.9 Folate deficiency anaemia, unspecified
0.780 0.220 0.000
N04.1 Focal and segmental glomerular lesions
0.779 0.221 0.000
D86.0 Sarcoidosis of lung
0.779 0.221 0.000
Q00-Q07 Congenital malformations of the nervous system
0.778 0.222 0.000
H35.8 Other specified retinal disorders
0.777 0.223 0.000
C83.7 Burkitt's tumour
0.776 0.224 0.000
M24.1 Other articular cartilage disorders
0.776 0.224 0.000
D69.2 Other nonthrombocytopenic purpura
0.776 0.224 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.775 0.225 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.775 0.225 0.000
D59 Acquired haemolytic anaemia
0.774 0.226 0.000
D64.8 Other specified anaemias
0.773 0.226 0.000
C85.1 B-cell lymphoma, unspecified
0.772 0.228 0.000
G12 Spinal muscular atrophy and related syndromes
0.771 0.229 0.000
E53.8 Deficiency of other specified B group vitamins
0.771 0.229 0.000
C81.9 Hodgkin's disease, unspecified
0.770 0.230 0.000
H31.0 Chorioretinal scars
0.770 0.230 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.767 0.233 0.000
M60.9 Myositis, unspecified
0.767 0.233 0.000
K73 Chronic hepatitis, not elsewhere classified
0.767 0.233 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.766 0.234 0.000
I74.5 Embolism and thrombosis of iliac artery
0.765 0.235 0.000
H35.6 Retinal haemorrhage
0.765 0.235 0.000
L13 Other bullous disorders
0.764 0.236 0.000
Q66 Congenital deformities of feet
0.764 0.236 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.763 0.237 0.000
M34.1 CR(E)ST syndrome
0.763 0.237 0.000
Q44.5 Other congenital malformations of bile ducts
0.763 0.237 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.762 0.238 0.000
C83.0 Small cell (diffuse)
0.762 0.238 0.000
D69.0 Allergic purpura
0.761 0.239 0.000
M21.1 Varus deformity, not elsewhere classified
0.760 0.240 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.760 0.240 0.000
G51.3 Clonic hemifacial spasm
0.760 0.240 0.000
G72 Other myopathies
0.758 0.242 0.000
G11 Hereditary ataxia
0.757 0.243 0.000
Q50-Q56 Congenital malformations of genital organs
0.757 0.243 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.244 0.756
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.756 0.244 0.000
E16.1 Other hypoglycaemia
0.754 0.246 0.000
K75.8 Other specified inflammatory liver diseases
0.754 0.246 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.754 0.246 0.000
N04.2 Diffuse membranous glomerulonephritis
0.754 0.246 0.000
D73.5 Infarction of spleen
0.753 0.247 0.000
N00 Acute nephritic syndrome
0.753 0.247 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.752 0.248 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.752 0.248 0.000
E31 Polyglandular dysfunction
0.752 0.248 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.752 0.248 0.000
Q68 Other congenital musculoskeletal deformities
0.752 0.248 0.000
N05.8 Other
0.752 0.248 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.751 0.249 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.749 0.251 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.749 0.251 0.000
I63.9 Cerebral infarction, unspecified
0.749 0.251 0.000
J45 Asthma
0.746 0.254 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.745 0.255 0.000
D70 Agranulocytosis
0.745 0.255 0.000
E14.1 With ketoacidosis
0.744 0.256 0.000
L28 Lichen simplex chronicus and prurigo
0.743 0.257 0.000
H10 Conjunctivitis
0.742 0.258 0.000
D89.1 Cryoglobulinaemia
0.741 0.259 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.741 0.259 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.740 0.260 0.000
C91.0 Acute lymphoblastic leukaemia
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.736 0.263 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.736 0.263 0.000
M35.1 Other overlap syndromes
0.736 0.264 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.735 0.265 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.735 0.265 0.000
K72.0 Acute and subacute hepatic failure
0.734 0.266 0.000
Q40 Other congenital malformations of upper alimentary tract
0.734 0.266 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.734 0.266 0.000
J92 Pleural plaque
0.733 0.267 0.000
I70 Atherosclerosis
0.731 0.269 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.731 0.269 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.730 0.269 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.730 0.270 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.271 0.729
N28 Other disorders of kidney and ureter, not elsewhere classified
0.729 0.271 0.000
L13.0 Dermatitis herpetiformis
0.727 0.273 0.000
E28.3 Primary ovarian failure
0.727 0.273 0.000
D50.8 Other iron deficiency anaemias
0.727 0.273 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.726 0.274 0.000
N18.4 Chronic kidney disease, stage 4
0.725 0.275 0.000
H30.9 Chorioretinal inflammation, unspecified
0.723 0.277 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.722 0.278 0.000
C91.5 Adult T-cell leukaemia
0.721 0.279 0.000
Q74 Other congenital malformations of limb(s)
0.721 0.279 0.000
E27.2 Addisonian crisis
0.720 0.280 0.000
E34 Other endocrine disorders
0.719 0.281 0.000
E88 Other metabolic disorders
0.719 0.281 0.000
E20 Hypoparathyroidism
0.718 0.281 0.000
B00 Herpesviral [herpes simplex] infections
0.718 0.282 0.000
M35.7 Hypermobility syndrome
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
T42.0 Hydantoin derivatives
0.000 0.283 0.717
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
H06.2 Dysthyroid exophthalmos
0.717 0.283 0.000
E14.7 With multiple complications
0.716 0.283 0.000
E14.0 With coma
0.716 0.283 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.716 0.284 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.716 0.284 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.716 0.284 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.716 0.284 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.716 0.284 0.000
E27.5 Adrenomedullary hyperfunction
0.716 0.284 0.000
E27.0 Other adrenocortical overactivity
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.284 0.000
A75-A79 Rickettsioses
0.715 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.284 0.000
Q43.0 Meckel's diverticulum
0.715 0.285 0.000
M65-M68 Disorders of synovium and tendon
0.715 0.285 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.714 0.286 0.000
D61.8 Other specified aplastic anaemias
0.713 0.287 0.000
D61.3 Idiopathic aplastic anaemia
0.713 0.287 0.000
D61.2 Aplastic anaemia due to other external agents
0.713 0.287 0.000
D61.0 Constitutional aplastic anaemia
0.713 0.287 0.000
M23.4 Loose body in knee
0.713 0.287 0.000
Q35-Q37 Cleft lip and cleft palate
0.713 0.287 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.713 0.287 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.713 0.287 0.000
E23.7 Disorder of pituitary gland, unspecified
0.713 0.287 0.000
C81.1 Nodular sclerosis
0.713 0.287 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
E14.6 With other specified complications
0.712 0.288 0.000
B33 Other viral diseases, not elsewhere classified
0.712 0.288 0.000
B30 Viral conjunctivitis
0.712 0.288 0.000
B26 Mumps
0.712 0.288 0.000
D67 Hereditary factor IX deficiency
0.712 0.288 0.000
N04.8 Other
0.711 0.289 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.711 0.289 0.000
N04.6 Dense deposit disease
0.711 0.289 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.711 0.289 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.711 0.289 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.711 0.289 0.000
N04.0 Minor glomerular abnormality
0.711 0.289 0.000
D69.8 Other specified haemorrhagic conditions
0.711 0.289 0.000
D69.1 Qualitative platelet defects
0.711 0.289 0.000
M62.6 Muscle strain
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
D50.1 Sideropenic dysphagia
0.710 0.290 0.000
B34.9 Viral infection, unspecified
0.710 0.290 0.000
E24.0 Pituitary-dependent Cushing's disease
0.710 0.290 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.710 0.290 0.000
N03.8 Other
0.709 0.291 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.708 0.292 0.000
B25.2 Cytomegaloviral pancreatitis
0.708 0.292 0.000
B25.1 Cytomegaloviral hepatitis
0.708 0.292 0.000
B25.0 Cytomegaloviral pneumonitis
0.708 0.292 0.000
M22.9 Disorder of patella, unspecified
0.708 0.292 0.000
K73.9 Chronic hepatitis, unspecified
0.708 0.292 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.707 0.293 0.000
G00.1 Pneumococcal meningitis
0.706 0.293 0.000
K72.9 Hepatic failure, unspecified
0.706 0.294 0.000
D81 Combined immunodeficiencies
0.705 0.295 0.000
D51.2 Transcobalamin II deficiency
0.705 0.295 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.705 0.295 0.000
K75.0 Abscess of liver
0.705 0.295 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.705 0.295 0.000
Q43.3 Congenital malformations of intestinal fixation
0.705 0.295 0.000
D82 Immunodeficiency associated with other major defects
0.704 0.296 0.000
L50-L54 Urticaria and erythema
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.703 0.297 0.000
Chapter XI Diseases of the digestive system
0.703 0.297 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.298 0.702
N05.9 Unspecified
0.702 0.298 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.701 0.299 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.700 0.300 0.000
G54.6 Phantom limb syndrome with pain
0.700 0.300 0.000
M22.3 Other derangements of patella
0.699 0.301 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.698 0.302 0.000
N25 Disorders resulting from impaired renal tubular function
0.698 0.302 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.697 0.303 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.697 0.303 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.697 0.303 0.000
A65-A69 Other spirochaetal diseases
0.697 0.303 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
M21.4 Flat foot [pes planus] (acquired)
0.696 0.304 0.000
B17 Other acute viral hepatitis
0.696 0.304 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.696 0.304 0.000
M61 Calcification and ossification of muscle
0.696 0.304 0.000
M83 Adult osteomalacia
0.696 0.304 0.000
M86 Osteomyelitis
0.696 0.304 0.000
E14.5 With peripheral circulatory complications
0.694 0.305 0.000
Q78 Other osteochondrodysplasias
0.694 0.306 0.000
J41 Simple and mucopurulent chronic bronchitis
0.694 0.306 0.000
H33.4 Traction detachment of retina
0.693 0.307 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.307 0.693
A87 Viral meningitis
0.693 0.307 0.000
C84.5 Other and unspecified T-cell lymphomas
0.693 0.307 0.000
G30.9 Alzheimer's disease, unspecified
0.692 0.308 0.000
Q65.8 Other congenital deformities of hip
0.692 0.308 0.000
Q43.8 Other specified congenital malformations of intestine
0.692 0.308 0.000
M80 Osteoporosis with pathological fracture
0.692 0.308 0.000
E03.8 Other specified hypothyroidism
0.691 0.309 0.000
T42.1 Iminostilbenes
0.000 0.309 0.691
M34.2 Systemic sclerosis induced by drugs and chemicals
0.691 0.309 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.691 0.309 0.000
N05.6 Dense deposit disease
0.691 0.309 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.691 0.309 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.691 0.309 0.000
N05.0 Minor glomerular abnormality
0.691 0.309 0.000
Q45 Other congenital malformations of digestive system
0.691 0.309 0.000
I74.8 Embolism and thrombosis of other arteries
0.691 0.309 0.000
A80 Acute poliomyelitis
0.691 0.309 0.000
E51 Thiamine deficiency
0.690 0.309 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.690 0.310 0.000
A59 Trichomoniasis
0.689 0.310 0.000
A56 Other sexually transmitted chlamydial diseases
0.689 0.310 0.000
A54 Gonococcal infection
0.689 0.310 0.000
A53 Other and unspecified syphilis
0.689 0.310 0.000
A52 Late syphilis
0.689 0.310 0.000
A51 Early syphilis
0.689 0.310 0.000
A50 Congenital syphilis
0.689 0.310 0.000
A64 Unspecified sexually transmitted disease
0.689 0.310 0.000
A58 Granuloma inguinale
0.689 0.310 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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