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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12524487
log Bayes Factor = 43.9884
Chromosome 6   position 31,354,238  (GRCh37) Explore rs12524487 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
E10.3 With ophthalmic complications
0.997 0.003 0.000
M05 Seropositive rheumatoid arthritis
0.994 0.006 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.994 0.006 0.000
E11 Non-insulin-dependent diabetes mellitus
0.993 0.007 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.991 0.009 0.000
H65-H75 Diseases of middle ear and mastoid
0.990 0.010 0.000
Chapter VIII Diseases of the ear and mastoid process
0.989 0.011 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
# Top node
0.988 0.012 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.983 0.017 0.000
E10.1 With ketoacidosis
0.975 0.025 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.973 0.027 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.970 0.030 0.000
E14 Unspecified diabetes mellitus
0.969 0.031 0.000
H72 Perforation of tympanic membrane
0.965 0.035 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.959 0.041 0.000
E16 Other disorders of pancreatic internal secretion
0.956 0.044 0.000
H65 Nonsuppurative otitis media
0.949 0.051 0.000
Chapter V Mental and behavioural disorders
0.944 0.056 0.000
E11.3 With ophthalmic complications
0.940 0.060 0.000
E10.4 With neurological complications
0.940 0.060 0.000
H30-H36 Disorders of choroid and retina
0.937 0.063 0.000
Chapter VII Diseases of the eye and adnexa
0.936 0.064 0.000
E16.2 Hypoglycaemia, unspecified
0.934 0.066 0.000
H36 Retinal disorders in diseases classified elsewhere
0.933 0.067 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.933 0.067 0.000
H36.0 Diabetic retinopathy
0.932 0.068 0.000
H65.3 Chronic mucoid otitis media
0.931 0.069 0.000
M70-M79 Other soft tissue disorders
0.926 0.074 0.000
E10.0 With coma
0.922 0.078 0.000
H90-H95 Other disorders of ear
0.922 0.078 0.000
E14.9 Without complications
0.907 0.093 0.000
H53-H54 Visual disturbances and blindness
0.904 0.096 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.900 0.100 0.000
F30-F39 Mood [affective] disorders
0.897 0.103 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.889 0.111 0.000
M86-M90 Other osteopathies
0.887 0.113 0.000
H71 Cholesteatoma of middle ear
0.882 0.118 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.875 0.125 0.000
H90 Conductive and sensorineural hearing loss
0.875 0.125 0.000
E10.2 With renal complications
0.871 0.129 0.000
M06.0 Seronegative rheumatoid arthritis
0.868 0.132 0.000
E11.4 With neurological complications
0.866 0.134 0.000
E11.1 With ketoacidosis
0.864 0.136 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.864 0.136 0.000
M75 Shoulder lesions
0.861 0.139 0.000
F32 Depressive episode
0.850 0.150 0.000
H73 Other disorders of tympanic membrane
0.849 0.151 0.000
H72.8 Other perforations of tympanic membrane
0.847 0.153 0.000
H53 Visual disturbances
0.847 0.153 0.000
E40-E46 Malnutrition
0.846 0.154 0.000
E11.0 With coma
0.838 0.162 0.000
M06.3 Rheumatoid nodule
0.838 0.162 0.000
E10.5 With peripheral circulatory complications
0.835 0.165 0.000
M80-M85 Disorders of bone density and structure
0.833 0.167 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.832 0.168 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.831 0.169 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.829 0.171 0.000
Q60-Q64 Congenital malformations of the urinary system
0.828 0.172 0.000
F32.9 Depressive episode, unspecified
0.825 0.175 0.000
E11.5 With peripheral circulatory complications
0.821 0.179 0.000
F03 Unspecified dementia
0.820 0.180 0.000
H74 Other disorders of middle ear and mastoid
0.815 0.185 0.000
E13 Other specified diabetes mellitus
0.814 0.185 0.000
E14.8 With unspecified complications
0.811 0.189 0.000
M75.0 Adhesive capsulitis of shoulder
0.809 0.191 0.000
H33 Retinal detachments and breaks
0.808 0.192 0.000
H90.2 Conductive hearing loss, unspecified
0.808 0.192 0.000
Q80-Q89 Other congenital malformations
0.805 0.195 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.803 0.197 0.000
E14.6 With other specified complications
0.801 0.198 0.000
H54 Blindness and low vision
0.801 0.199 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.800 0.200 0.000
H53.8 Other visual disturbances
0.791 0.209 0.000
H53.4 Visual field defects
0.790 0.210 0.000
H70 Mastoiditis and related conditions
0.786 0.213 0.000
M14 Arthropathies in other diseases classified elsewhere
0.786 0.214 0.000
E03 Other hypothyroidism
0.035 0.214 0.751
H34 Retinal vascular occlusions
0.786 0.214 0.000
H33.2 Serous retinal detachment
0.785 0.215 0.000
E10.8 With unspecified complications
0.774 0.226 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.773 0.227 0.000
H72.1 Attic perforation of tympanic membrane
0.772 0.228 0.000
E11.6 With other specified complications
0.771 0.229 0.000
F30 Manic episode
0.768 0.232 0.000
M06.4 Inflammatory polyarthropathy
0.767 0.233 0.000
M10 Gout
0.767 0.233 0.000
E10.6 With other specified complications
0.766 0.234 0.000
H65.2 Chronic serous otitis media
0.764 0.236 0.000
H66 Suppurative and unspecified otitis media
0.762 0.238 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.759 0.241 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.759 0.241 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.758 0.241 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.756 0.244 0.000
M77 Other enthesopathies
0.753 0.247 0.000
H72.0 Central perforation of tympanic membrane
0.750 0.250 0.000
M80 Osteoporosis with pathological fracture
0.750 0.250 0.000
H73.8 Other specified disorders of tympanic membrane
0.747 0.253 0.000
M87 Osteonecrosis
0.746 0.254 0.000
M75.3 Calcific tendinitis of shoulder
0.738 0.262 0.000
E11.2 With renal complications
0.738 0.262 0.000
E46 Unspecified protein-energy malnutrition
0.737 0.262 0.000
M11 Other crystal arthropathies
0.736 0.264 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.736 0.264 0.000
M76 Enthesopathies of lower limb, excluding foot
0.731 0.269 0.000
E11.8 With unspecified complications
0.726 0.274 0.000
F32.0 Mild depressive episode
0.725 0.275 0.000
M65-M68 Disorders of synovium and tendon
0.723 0.277 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.722 0.278 0.000
M71 Other bursopathies
0.722 0.278 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.721 0.279 0.000
H69 Other disorders of Eustachian tube
0.720 0.280 0.000
Q85 Phakomatoses, not elsewhere classified
0.717 0.282 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M86 Osteomyelitis
0.715 0.285 0.000
E50-E64 Other nutritional deficiencies
0.714 0.286 0.000
F60-F69 Disorders of adult personality and behaviour
0.714 0.286 0.000
Q61 Cystic kidney disease
0.714 0.286 0.000
Chapter XXII Codes for special purposes
0.713 0.286 0.000
M05.8 Other seropositive rheumatoid arthritis
0.713 0.287 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.713 0.287 0.000
M05.2 Rheumatoid vasculitis
0.713 0.287 0.000
M05.1 Rheumatoid lung disease
0.713 0.287 0.000
M05.0 Felty's syndrome
0.713 0.287 0.000
F31 Bipolar affective disorder
0.713 0.287 0.000
F41 Other anxiety disorders
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.287 0.000
E11.7 With multiple complications
0.712 0.288 0.000
Q66 Congenital deformities of feet
0.712 0.288 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.711 0.289 0.000
H43-H45 Disorders of vitreous body and globe
0.711 0.289 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.710 0.290 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.710 0.290 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.710 0.290 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.710 0.290 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.710 0.290 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.710 0.290 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.710 0.290 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.710 0.290 0.000
H31 Other disorders of choroid
0.710 0.290 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.710 0.290 0.000
H68 Eustachian salpingitis and obstruction
0.710 0.290 0.000
H67 Otitis media in diseases classified elsewhere
0.710 0.290 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.708 0.292 0.000
H90.3 Sensorineural hearing loss, bilateral
0.705 0.295 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.699 0.301 0.000
E15 Nondiabetic hypoglycaemic coma
0.698 0.302 0.000
Chapter X Diseases of the respiratory system
0.696 0.304 0.000
E14.7 With multiple complications
0.695 0.305 0.000
E14.5 With peripheral circulatory complications
0.695 0.305 0.000
E14.4 With neurological complications
0.695 0.305 0.000
E14.2 Withrenal complications
0.695 0.305 0.000
E14.1 With ketoacidosis
0.695 0.305 0.000
E14.0 With coma
0.695 0.305 0.000
H60-H62 Diseases of external ear
0.692 0.308 0.000
E14.3 With ophthalmic complications
0.692 0.308 0.000
H72.2 Other marginal perforations of tympanic membrane
0.692 0.308 0.000
H90.5 Sensorineural hearing loss, unspecified
0.690 0.310 0.000
F39 Unspecified mood [affective] disorder
0.690 0.310 0.000
F02 Dementia in other diseases classified elsewhere
0.689 0.311 0.000
H92 Otalgia and effusion of ear
0.686 0.314 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.685 0.315 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.685 0.315 0.000
E16.4 Abnormal secretion of gastrin
0.685 0.315 0.000
E16.3 Increased secretion of glucagon
0.685 0.315 0.000
E16.1 Other hypoglycaemia
0.685 0.315 0.000
E13.9 Without complications
0.682 0.318 0.000
M60-M63 Disorders of muscles
0.681 0.319 0.000
H65.1 Other acute nonsuppurative otitis media
0.680 0.320 0.000
H65.0 Acute serous otitis media
0.680 0.320 0.000
M82 Osteoporosis in diseases classified elsewhere
0.680 0.320 0.000
F41.2 Mixed anxiety and depressive disorder
0.679 0.321 0.000
H54.4 Blindness, one eye
0.678 0.322 0.000
M06.34 Rheumatoid nodule (Hand)
0.678 0.322 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.677 0.323 0.000
F70-F79 Mental retardation
0.677 0.323 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.676 0.324 0.000
M87.9 Osteonecrosis, unspecified
0.674 0.326 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.672 0.328 0.000
H30 Chorioretinal inflammation
0.672 0.328 0.000
M88 Paget's disease of bone [osteitis deformans]
0.669 0.331 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.669 0.331 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.669 0.331 0.000
Q35-Q37 Cleft lip and cleft palate
0.669 0.331 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.669 0.331 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.665 0.335 0.000
E20-E35 Disorders of other endocrine glands
0.664 0.336 0.000
M75.1 Rotator cuff syndrome
0.664 0.336 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.664 0.336 0.000
M90 Osteopathies in diseases classified elsewhere
0.664 0.336 0.000
H34.1 Central retinal artery occlusion
0.663 0.337 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.663 0.337 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.662 0.338 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.661 0.339 0.000
H74.1 Adhesive middle ear disease
0.660 0.340 0.000
J40-J47 Chronic lower respiratory diseases
0.660 0.340 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.660 0.340 0.000
H93 Other disorders of ear, not elsewhere classified
0.654 0.346 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.653 0.346 0.000
M77.9 Enthesopathy, unspecified
0.653 0.347 0.000
F06.7 Mild cognitive disorder
0.653 0.347 0.000
E65-E68 Obesity and other hyperalimentation
0.652 0.348 0.000
M72 Fibroblastic disorders
0.652 0.348 0.000
H53.0 Amblyopia ex anopsia
0.646 0.354 0.000
Q83 Congenital malformations of breast
0.645 0.355 0.000
J47 Bronchiectasis
0.645 0.355 0.000
M89 Other disorders of bone
0.644 0.356 0.000
F38 Other mood [affective] disorders
0.643 0.357 0.000
H95.1 Other disorders following mastoidectomy
0.642 0.358 0.000
H74.4 Polyp of middle ear
0.642 0.358 0.000
H70.8 Other mastoiditis and related conditions
0.640 0.359 0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease
0.640 0.360 0.000
H34.2 Other retinal artery occlusions
0.639 0.361 0.000
J45 Asthma
0.639 0.361 0.000
M91-M94 Chondropathies
0.638 0.362 0.000
Q23 Congenital malformations of aortic and mitral valves
0.638 0.362 0.000
F80-F89 Disorders of psychological development
0.638 0.362 0.000
E03.8 Other specified hypothyroidism
0.019 0.364 0.618
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.635 0.365 0.000
J00-J06 Acute upper respiratory infections
0.635 0.365 0.000
F34 Persistent mood [affective] disorders
0.635 0.365 0.000
M14.6 Neuropathic arthropathy
0.633 0.367 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.630 0.369 0.000
H54.7 Unspecified visual loss
0.630 0.370 0.000
F30.0 Hypomania
0.628 0.372 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.628 0.372 0.000
F09 Unspecified organic or symptomatic mental disorder
0.628 0.372 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.628 0.372 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.627 0.373 0.000
F30.9 Manic episode, unspecified
0.626 0.374 0.000
J45.9 Asthma, unspecified
0.625 0.375 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.625 0.375 0.000
H33.4 Traction detachment of retina
0.625 0.375 0.000
Q66.8 Other congenital deformities of feet
0.624 0.376 0.000
H66.3 Other chronic suppurative otitis media
0.624 0.376 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.622 0.377 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.622 0.377 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.622 0.377 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.622 0.377 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.622 0.377 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.622 0.377 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.622 0.377 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.622 0.377 0.000
H90.0 Conductive hearing loss, bilateral
0.621 0.379 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.620 0.379 0.000
M13 Other arthritis
0.619 0.381 0.000
H54.0 Blindness, both eyes
0.619 0.381 0.000
F44 Dissociative [conversion] disorders
0.618 0.381 0.000
M75.8 Other shoulder lesions
0.618 0.382 0.000
M40-M43 Deforming dorsopathies
0.617 0.383 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.615 0.385 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.614 0.386 0.000
Q65 Congenital deformities of hip
0.609 0.390 0.000
F32.8 Other depressive episodes
0.609 0.391 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.608 0.391 0.000
H73.1 Chronic myringitis
0.608 0.391 0.000
H73.0 Acute myringitis
0.608 0.391 0.000
H53.6 Night blindness
0.608 0.392 0.000
H53.5 Colour vision deficiencies
0.608 0.392 0.000
H53.3 Other disorders of binocular vision
0.608 0.392 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.606 0.393 0.000
E45 Retarded development following protein-energy malnutrition
0.606 0.393 0.000
E43 Unspecified severe protein-energy malnutrition
0.606 0.393 0.000
E42 Marasmic kwashiorkor
0.606 0.393 0.000
E41 Nutritional marasmus
0.606 0.393 0.000
E40 Kwashiorkor
0.606 0.393 0.000
M75.9 Shoulder lesion, unspecified
0.603 0.397 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.603 0.397 0.000
H43 Disorders of vitreous body
0.602 0.398 0.000
J06.9 Acute upper respiratory infection, unspecified
0.602 0.398 0.000
H35 Other retinal disorders
0.602 0.398 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.600 0.399 0.000
M06.38 Rheumatoid nodule (Other)
0.600 0.399 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.600 0.399 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.600 0.399 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.600 0.399 0.000
M06.33 Rheumatoid nodule (Forearm)
0.600 0.399 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.600 0.399 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.600 0.399 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.600 0.400 0.000
M10.9 Gout, unspecified
0.600 0.400 0.000
Q27 Other congenital malformations of peripheral vascular system
0.599 0.401 0.000
H74.0 Tympanosclerosis
0.599 0.401 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.599 0.401 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.599 0.401 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.599 0.401 0.000
M83 Adult osteomalacia
0.597 0.403 0.000
F99-F99 Unspecified mental disorder
0.596 0.404 0.000
F41.9 Anxiety disorder, unspecified
0.595 0.405 0.000
Q64 Other congenital malformations of urinary system
0.593 0.406 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.593 0.406 0.000
M07 Psoriatic and enteropathic arthropathies
0.592 0.407 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.592 0.408 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.592 0.408 0.000
M86.9 Osteomyelitis, unspecified
0.591 0.408 0.000
Q89 Other congenital malformations, not elsewhere classified
0.590 0.410 0.000
E00-E07 Disorders of thyroid gland
0.145 0.410 0.445
M71.3 Other bursal cyst
0.588 0.411 0.000
Q61.2 Polycystic kidney, adult type
0.588 0.412 0.000
M75.5 Bursitis of shoulder
0.588 0.412 0.000
Q63 Other congenital malformations of kidney
0.587 0.413 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.584 0.416 0.000
E13.8 With unspecified complications
0.584 0.416 0.000
E13.7 With multiple complications
0.584 0.416 0.000
E13.6 With other specified complications
0.584 0.416 0.000
E13.5 With peripheral circulatory complications
0.584 0.416 0.000
E13.4 With neurological complications
0.584 0.416 0.000
E13.3 With ophthalmic complications
0.584 0.416 0.000
E13.2 With renal complications
0.584 0.416 0.000
E13.1 With ketoacidosis
0.584 0.416 0.000
E13.0 With coma
0.584 0.416 0.000
Q85.9 Phakomatosis, unspecified
0.580 0.420 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.580 0.420 0.000
H33.1 Retinoschisis and retinal cysts
0.580 0.420 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.579 0.421 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.578 0.422 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.577 0.423 0.000
Q84 Other congenital malformations of integument
0.577 0.423 0.000
Q81 Epidermolysis bullosa
0.577 0.423 0.000
Q80 Congenital ichthyosis
0.577 0.423 0.000
H54.6 Unqualified visual loss, one eye
0.574 0.426 0.000
H54.5 Low vision, one eye
0.574 0.426 0.000
H54.3 Unqualified visual loss, both eyes
0.574 0.426 0.000
H54.2 Low vision, both eyes
0.574 0.426 0.000
H54.1 Blindness, one eye, low vision, other eye
0.574 0.426 0.000
H54.9 Unspecified visual impairment (binocular)
0.574 0.426 0.000
Q78 Other osteochondrodysplasias
0.573 0.426 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.573 0.426 0.000
Q75 Other congenital malformations of skull and face bones
0.573 0.426 0.000
Q74 Other congenital malformations of limb(s)
0.573 0.426 0.000
Q73 Reduction defects of unspecified limb
0.573 0.426 0.000
Q72 Reduction defects of lower limb
0.573 0.426 0.000
Q71 Reduction defects of upper limb
0.573 0.426 0.000
Q70 Syndactyly
0.573 0.426 0.000
Q69 Polydactyly
0.573 0.426 0.000
Q68 Other congenital musculoskeletal deformities
0.573 0.426 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.573 0.426 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.573 0.427 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.572 0.428 0.000
M85 Other disorders of bone density and structure
0.571 0.429 0.000
M82.1 Osteoporosis in endocrine disorders
0.571 0.429 0.000
Q60.0 Renal agenesis, unilateral
0.568 0.432 0.000
Q66.3 Other congenital varus deformities of feet
0.568 0.432 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.566 0.434 0.000
J60-J70 Lung diseases due to external agents
0.564 0.436 0.000
H70.9 Mastoiditis, unspecified
0.564 0.436 0.000
H70.2 Petrositis
0.564 0.436 0.000
H70.1 Chronic mastoiditis
0.564 0.436 0.000
H70.0 Acute mastoiditis
0.564 0.436 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.564 0.436 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.564 0.436 0.000
M14.4 Arthropathy in amyloidosis
0.564 0.436 0.000
M14.3 Lipoid dermatoarthritis
0.564 0.436 0.000
M14.2 Diabetic arthropathy
0.564 0.436 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.564 0.436 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.564 0.436 0.000
E03.5 Myxoedema coma
0.025 0.436 0.539
E03.4 Atrophy of thyroid (acquired)
0.025 0.436 0.539
E03.3 Postinfectious hypothyroidism
0.025 0.436 0.539
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.025 0.436 0.539
E03.1 Congenital hypothyroidism without goitre
0.025 0.436 0.539
E03.0 Congenital hypothyroidism with diffuse goitre
0.025 0.436 0.539
H34.9 Retinal vascular occlusion, unspecified
0.563 0.437 0.000
H34.0 Transient retinal artery occlusion
0.563 0.437 0.000
F01 Vascular dementia
0.561 0.438 0.000
Q00-Q07 Congenital malformations of the nervous system
0.560 0.440 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.559 0.441 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.558 0.442 0.000
E55 Vitamin D deficiency
0.558 0.442 0.000
H92.1 Otorrhoea
0.557 0.443 0.000
E70-E90 Metabolic disorders
0.556 0.444 0.000
M65 Synovitis and tenosynovitis
0.556 0.444 0.000
M79.1 Myalgia
0.555 0.445 0.000
H53.1 Subjective visual disturbances
0.555 0.445 0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease
0.554 0.446 0.000
F06.6 Organic emotionally labile [asthenic] disorder
0.554 0.446 0.000
F06.5 Organic dissociative disorder
0.554 0.446 0.000
F06.4 Organic anxiety disorder
0.554 0.446 0.000
F06.3 Organic mood [affective] disorders
0.554 0.446 0.000
F06.2 Organic delusional [schizophrenia-like] disorder
0.554 0.446 0.000
F06.1 Organic catatonic disorder
0.554 0.446 0.000
F06.0 Organic hallucinosis
0.554 0.446 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.554 0.446 0.000
E65 Localised adiposity
0.553 0.446 0.000
E22 Hyperfunction of pituitary gland
0.553 0.447 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.553 0.447 0.000
Q61.3 Polycystic kidney, unspecified
0.553 0.447 0.000
Q24 Other congenital malformations of heart
0.552 0.448 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.552 0.448 0.000
F30.8 Other manic episodes
0.551 0.449 0.000
F30.2 Mania with psychotic symptoms
0.551 0.449 0.000
F30.1 Mania without psychotic symptoms
0.551 0.449 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.551 0.449 0.000
M66 Spontaneous rupture of synovium and tendon
0.550 0.449 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.550 0.450 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.550 0.450 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.550 0.450 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.550 0.450 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.550 0.450 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.550 0.450 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.550 0.450 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.550 0.450 0.000
H31.0 Chorioretinal scars
0.550 0.450 0.000
M10.4 Other secondary gout
0.550 0.450 0.000
M10.3 Gout due to impairment of renal function
0.550 0.450 0.000
M10.2 Drug-induced gout
0.550 0.450 0.000
M10.1 Lead-induced gout
0.550 0.450 0.000
M10.0 Idiopathic gout
0.550 0.450 0.000
F60 Specific personality disorders
0.549 0.451 0.000
Q61.0 Congenital single renal cyst
0.549 0.451 0.000
M75.4 Impingement syndrome of shoulder
0.548 0.452 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.548 0.452 0.000
M11.2 Other chondrocalcinosis
0.547 0.453 0.000
H43.1 Vitreous haemorrhage
0.547 0.453 0.000
H66.4 Suppurative otitis media, unspecified
0.547 0.453 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.547 0.453 0.000
H66.0 Acute suppurative otitis media
0.547 0.453 0.000
M84 Disorders of continuity of bone
0.546 0.454 0.000
H60 Otitis externa
0.546 0.454 0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified
0.544 0.456 0.000
H95.8 Other postprocedural disorders of ear and mastoid process
0.544 0.456 0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity
0.544 0.456 0.000
Q26 Congenital malformations of great veins
0.544 0.456 0.000
Q25 Congenital malformations of great arteries
0.544 0.456 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.544 0.456 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.544 0.456 0.000
F48 Other neurotic disorders
0.544 0.456 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.543 0.456 0.000
H69.8 Other specified disorders of Eustachian tube
0.542 0.458 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.540 0.460 0.000
M77.8 Other enthesopathies, not elsewhere classified
0.540 0.460 0.000
M77.5 Other enthesopathy of foot
0.540 0.460 0.000
M77.3 Calcaneal spur
0.540 0.460 0.000
M77.2 Periarthritis of wrist
0.540 0.460 0.000
E34 Other endocrine disorders
0.540 0.460 0.000
F41.1 Generalised anxiety disorder
0.540 0.460 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.538 0.462 0.000
M80.8 Other osteoporosis with pathological fracture
0.538 0.462 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.538 0.462 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.538 0.462 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.538 0.462 0.000
Q23.0 Congenital stenosis of aortic valve
0.536 0.464 0.000
H93.9 Disorder of ear, unspecified
0.536 0.464 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.536 0.464 0.000
M77.1 Lateral epicondylitis
0.535 0.464 0.000
M87.8 Other osteonecrosis
0.535 0.465 0.000
M87.3 Other secondary osteonecrosis
0.535 0.465 0.000
M87.1 Osteonecrosis due to drugs
0.535 0.465 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.535 0.465 0.000
H35.8 Other specified retinal disorders
0.533 0.467 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.532 0.468 0.000
M77.0 Medial epicondylitis
0.532 0.468 0.000
F50 Eating disorders
0.531 0.469 0.000
Q76 Congenital malformations of spine and bony thorax
0.530 0.470 0.000
H33.3 Retinal breaks without detachment
0.530 0.470 0.000
Q83.1 Accessory breast
0.530 0.470 0.000
M11.9 Crystal arthropathy, unspecified
0.528 0.472 0.000
M11.8 Other specified crystal arthropathies
0.528 0.472 0.000
M11.1 Familial chondrocalcinosis
0.528 0.472 0.000
M11.0 Hydroxyapatite deposition disease
0.528 0.472 0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)
0.527 0.473 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.526 0.474 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.525 0.475 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.525 0.475 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.525 0.475 0.000
M76.9 Enthesopathy of lower limb, unspecified
0.524 0.476 0.000
M76.7 Peroneal tendinitis
0.524 0.476 0.000
M76.5 Patellar tendinitis
0.524 0.476 0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]
0.524 0.476 0.000
M76.3 Iliotibial band syndrome
0.524 0.476 0.000
M76.2 Iliac crest spur
0.524 0.476 0.000
M76.1 Psoas tendinitis
0.524 0.476 0.000
M76.0 Gluteal tendinitis
0.524 0.476 0.000
F02.3 Dementia in Parkinson's disease
0.523 0.477 0.000
E53 Deficiency of other B group vitamins
0.522 0.478 0.000
M75.2 Bicipital tendinitis
0.519 0.481 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.519 0.481 0.000
J45.1 Nonallergic asthma
0.518 0.482 0.000
J03 Acute tonsillitis
0.518 0.482 0.000
F44.4 Dissociative motor disorders
0.518 0.482 0.000
M71.9 Bursopathy, unspecified
0.517 0.482 0.000
M71.8 Other specified bursopathies
0.517 0.482 0.000
M71.5 Other bursitis, not elsewhere classified
0.517 0.482 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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