TreeWAS – Variant ID: rs9380254

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E10.9 Without complications	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter VIII Diseases of the ear and mastoid process	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
H65-H75 Diseases of middle ear and mastoid	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
E10.3 With ophthalmic complications	0.998	0.002	0.000
Chapter VII Diseases of the eye and adnexa	0.991	0.009	0.000
H30-H36 Disorders of choroid and retina	0.988	0.012	0.000
H72 Perforation of tympanic membrane	0.984	0.016	0.000
H36 Retinal disorders in diseases classified elsewhere	0.982	0.018	0.000
E10.1 With ketoacidosis	0.981	0.019	0.000
E14 Unspecified diabetes mellitus	0.980	0.020	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.979	0.021	0.000
H36.0 Diabetic retinopathy	0.978	0.022	0.000
H90-H95 Other disorders of ear	0.973	0.027	0.000
E11 Non-insulin-dependent diabetes mellitus	0.972	0.028	0.000
M05 Seropositive rheumatoid arthritis	0.968	0.032	0.000
H53-H54 Visual disturbances and blindness	0.967	0.033	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.966	0.034	0.000
H65 Nonsuppurative otitis media	0.960	0.040	0.000
M70-M79 Other soft tissue disorders	0.960	0.040	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.959	0.041	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.957	0.043	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.945	0.055	0.000
H65.3 Chronic mucoid otitis media	0.945	0.055	0.000
H90 Conductive and sensorineural hearing loss	0.944	0.056	0.000
E16 Other disorders of pancreatic internal secretion	0.942	0.058	0.000
E14.9 Without complications	0.937	0.063	0.000
E10.4 With neurological complications	0.933	0.067	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.926	0.074	0.000
E10.0 With coma	0.918	0.082	0.000
E16.2 Hypoglycaemia, unspecified	0.916	0.084	0.000
E50-E64 Other nutritional deficiencies	0.914	0.086	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.912	0.088	0.000
H43-H45 Disorders of vitreous body and globe	0.906	0.094	0.000
H54 Blindness and low vision	0.905	0.095	0.000
M75 Shoulder lesions	0.902	0.098	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.900	0.100	0.000
E03 Other hypothyroidism	0.016	0.101	0.883
E10.2 With renal complications	0.898	0.102	0.000
H60-H62 Diseases of external ear	0.898	0.102	0.000
H34 Retinal vascular occlusions	0.891	0.109	0.000
H71 Cholesteatoma of middle ear	0.890	0.110	0.000
H53 Visual disturbances	0.890	0.110	0.000
E11.3 With ophthalmic complications	0.888	0.112	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.887	0.113	0.000
M86-M90 Other osteopathies	0.878	0.122	0.000
H72.8 Other perforations of tympanic membrane	0.877	0.123	0.000
M06.0 Seronegative rheumatoid arthritis	0.876	0.124	0.000
H90.2 Conductive hearing loss, unspecified	0.861	0.139	0.000
H43 Disorders of vitreous body	0.861	0.139	0.000
H73 Other disorders of tympanic membrane	0.849	0.151	0.000
M72 Fibroblastic disorders	0.846	0.154	0.000
M10 Gout	0.846	0.154	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.843	0.157	0.000
H66 Suppurative and unspecified otitis media	0.843	0.157	0.000
Q60-Q64 Congenital malformations of the urinary system	0.842	0.158	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.838	0.162	0.000
H90.5 Sensorineural hearing loss, unspecified	0.835	0.165	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.831	0.169	0.000
E11.1 With ketoacidosis	0.828	0.172	0.000
E11.0 With coma	0.827	0.173	0.000
H53.4 Visual field defects	0.825	0.175	0.000
H43.1 Vitreous haemorrhage	0.824	0.176	0.000
M80-M85 Disorders of bone density and structure	0.824	0.176	0.000
Chapter X Diseases of the respiratory system	0.821	0.179	0.000
E55 Vitamin D deficiency	0.819	0.181	0.000
E00-E07 Disorders of thyroid gland	0.057	0.181	0.762
Chapter V Mental and behavioural disorders	0.818	0.182	0.000
H31 Other disorders of choroid	0.814	0.186	0.000
E10.5 With peripheral circulatory complications	0.813	0.187	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.812	0.188	0.000
H74 Other disorders of middle ear and mastoid	0.811	0.189	0.000
E40-E46 Malnutrition	0.809	0.191	0.000
E14.8 With unspecified complications	0.808	0.192	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.807	0.193	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.805	0.194	0.000
H90.3 Sensorineural hearing loss, bilateral	0.805	0.195	0.000
E11.4 With neurological complications	0.804	0.196	0.000
Q80-Q89 Other congenital malformations	0.803	0.197	0.000
H72.0 Central perforation of tympanic membrane	0.802	0.198	0.000
M75.0 Adhesive capsulitis of shoulder	0.800	0.200	0.000
M65-M68 Disorders of synovium and tendon	0.800	0.200	0.000
H70 Mastoiditis and related conditions	0.800	0.200	0.000
J40-J47 Chronic lower respiratory diseases	0.797	0.203	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.796	0.203	0.000
H92 Otalgia and effusion of ear	0.796	0.204	0.000
E14.6 With other specified complications	0.796	0.204	0.000
H53.8 Other visual disturbances	0.790	0.210	0.000
J45 Asthma	0.785	0.215	0.000
E10.6 With other specified complications	0.783	0.217	0.000
H61 Other disorders of external ear	0.782	0.218	0.000
E53 Deficiency of other B group vitamins	0.778	0.222	0.000
H72.1 Attic perforation of tympanic membrane	0.775	0.225	0.000
E11.6 With other specified complications	0.775	0.225	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.773	0.227	0.000
M11 Other crystal arthropathies	0.772	0.227	0.000
J45.9 Asthma, unspecified	0.772	0.228	0.000
M14 Arthropathies in other diseases classified elsewhere	0.772	0.228	0.000
E10.8 With unspecified complications	0.771	0.229	0.000
H34.1 Central retinal artery occlusion	0.769	0.231	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.768	0.232	0.000
M06.3 Rheumatoid nodule	0.765	0.234	0.000
E20-E35 Disorders of other endocrine glands	0.763	0.237	0.000
H54.4 Blindness, one eye	0.762	0.238	0.000
H65.2 Chronic serous otitis media	0.761	0.239	0.000
E14.3 With ophthalmic complications	0.759	0.241	0.000
J47 Bronchiectasis	0.755	0.245	0.000
M75.1 Rotator cuff syndrome	0.754	0.246	0.000
M87 Osteonecrosis	0.753	0.247	0.000
M75.5 Bursitis of shoulder	0.753	0.247	0.000
E55.9 Vitamin D deficiency, unspecified	0.752	0.248	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.749	0.251	0.000
H93 Other disorders of ear, not elsewhere classified	0.747	0.253	0.000
Q66 Congenital deformities of feet	0.744	0.256	0.000
E11.5 With peripheral circulatory complications	0.741	0.259	0.000
H73.8 Other specified disorders of tympanic membrane	0.741	0.259	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.740	0.260	0.000
E11.8 With unspecified complications	0.738	0.262	0.000
M76 Enthesopathies of lower limb, excluding foot	0.738	0.262	0.000
H60 Otitis externa	0.737	0.263	0.000
M10.9 Gout, unspecified	0.736	0.264	0.000
H66.3 Other chronic suppurative otitis media	0.736	0.264	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.736	0.264	0.000
M00-M03 Infectious arthropathies	0.735	0.265	0.000
M75.3 Calcific tendinitis of shoulder	0.734	0.266	0.000
H34.8 Other retinal vascular occlusions	0.734	0.266	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.730	0.270	0.000
H54.1 Blindness, one eye, low vision, other eye	0.728	0.272	0.000
H54.9 Unspecified visual impairment (binocular)	0.726	0.274	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.725	0.275	0.000
M06.4 Inflammatory polyarthropathy	0.725	0.275	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.724	0.276	0.000
Q85 Phakomatoses, not elsewhere classified	0.721	0.279	0.000
M60-M63 Disorders of muscles	0.720	0.280	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.720	0.280	0.000
M80 Osteoporosis with pathological fracture	0.720	0.280	0.000
H43.3 Other vitreous opacities	0.719	0.281	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.719	0.281	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.717	0.283	0.000
H68 Eustachian salpingitis and obstruction	0.717	0.283	0.000
H67 Otitis media in diseases classified elsewhere	0.717	0.283	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
Q61 Cystic kidney disease	0.716	0.283	0.000
H54.7 Unspecified visual loss	0.714	0.286	0.000
M77 Other enthesopathies	0.713	0.287	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.032	0.289	0.680
E03.8 Other specified hypothyroidism	0.009	0.289	0.701
E13 Other specified diabetes mellitus	0.711	0.289	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.708	0.292	0.000
H30 Chorioretinal inflammation	0.708	0.292	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.708	0.292	0.000
H69 Other disorders of Eustachian tube	0.708	0.292	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.706	0.294	0.000
H72.2 Other marginal perforations of tympanic membrane	0.706	0.294	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.704	0.296	0.000
H92.1 Otorrhoea	0.704	0.296	0.000
E14.7 With multiple complications	0.703	0.297	0.000
E14.5 With peripheral circulatory complications	0.703	0.297	0.000
E14.4 With neurological complications	0.703	0.297	0.000
E14.2 Withrenal complications	0.703	0.297	0.000
E14.1 With ketoacidosis	0.703	0.297	0.000
E14.0 With coma	0.703	0.297	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.698	0.302	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.698	0.302	0.000
E11.7 With multiple complications	0.697	0.303	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.695	0.305	0.000
M05.8 Other seropositive rheumatoid arthritis	0.694	0.306	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.694	0.306	0.000
M05.2 Rheumatoid vasculitis	0.694	0.306	0.000
M05.1 Rheumatoid lung disease	0.694	0.306	0.000
M05.0 Felty's syndrome	0.694	0.306	0.000
E15 Nondiabetic hypoglycaemic coma	0.693	0.307	0.000
Q23 Congenital malformations of aortic and mitral valves	0.690	0.310	0.000
H65.1 Other acute nonsuppurative otitis media	0.688	0.312	0.000
H65.0 Acute serous otitis media	0.688	0.312	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.688	0.312	0.000
Chapter XXII Codes for special purposes	0.688	0.312	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.687	0.313	0.000
Q35-Q37 Cleft lip and cleft palate	0.687	0.313	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.687	0.313	0.000
M87.9 Osteonecrosis, unspecified	0.686	0.314	0.000
M75.9 Shoulder lesion, unspecified	0.686	0.314	0.000
H95.1 Other disorders following mastoidectomy	0.685	0.315	0.000
M91-M94 Chondropathies	0.685	0.315	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.681	0.319	0.000
H54.0 Blindness, both eyes	0.680	0.319	0.000
H31.0 Chorioretinal scars	0.679	0.321	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.677	0.323	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.677	0.323	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.677	0.323	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.677	0.323	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.677	0.323	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.677	0.323	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.677	0.323	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.677	0.323	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.677	0.323	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.676	0.324	0.000
F03 Unspecified dementia	0.676	0.324	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.676	0.324	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.676	0.324	0.000
E16.4 Abnormal secretion of gastrin	0.676	0.324	0.000
E16.3 Increased secretion of glucagon	0.676	0.324	0.000
E16.1 Other hypoglycaemia	0.676	0.324	0.000
M82 Osteoporosis in diseases classified elsewhere	0.676	0.324	0.000
E65-E68 Obesity and other hyperalimentation	0.674	0.326	0.000
E46 Unspecified protein-energy malnutrition	0.672	0.328	0.000
M90 Osteopathies in diseases classified elsewhere	0.670	0.330	0.000
E70-E90 Metabolic disorders	0.670	0.330	0.000
E22 Hyperfunction of pituitary gland	0.669	0.331	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.669	0.331	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.668	0.332	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.668	0.332	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.667	0.333	0.000
M88 Paget's disease of bone [osteitis deformans]	0.667	0.333	0.000
J42 Unspecified chronic bronchitis	0.667	0.333	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.666	0.334	0.000
H34.2 Other retinal artery occlusions	0.663	0.337	0.000
E11.2 With renal complications	0.662	0.337	0.000
H61.2 Impacted cerumen	0.662	0.338	0.000
E05.9 Thyrotoxicosis, unspecified	0.002	0.338	0.660
E53.8 Deficiency of other specified B group vitamins	0.661	0.339	0.000
H35 Other retinal disorders	0.659	0.341	0.000
H70.8 Other mastoiditis and related conditions	0.657	0.343	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.655	0.345	0.000
E63 Other nutritional deficiencies	0.655	0.345	0.000
E56 Other vitamin deficiencies	0.655	0.345	0.000
E51 Thiamine deficiency	0.655	0.345	0.000
E50 Vitamin A deficiency	0.655	0.345	0.000
E60 Dietary zinc deficiency	0.655	0.345	0.000
E59 Dietary selenium deficiency	0.655	0.345	0.000
E58 Dietary calcium deficiency	0.655	0.345	0.000
E54 Ascorbic acid deficiency	0.655	0.345	0.000
E52 Niacin deficiency [pellagra]	0.655	0.345	0.000
H53.0 Amblyopia ex anopsia	0.653	0.347	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.653	0.347	0.000
Q66.8 Other congenital deformities of feet	0.651	0.349	0.000
J00-J06 Acute upper respiratory infections	0.650	0.349	0.000
R30-R39 Symptoms and signs involving the urinary system	0.650	0.350	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.650	0.350	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.649	0.350	0.000
H54.6 Unqualified visual loss, one eye	0.649	0.351	0.000
H54.5 Low vision, one eye	0.649	0.351	0.000
H54.3 Unqualified visual loss, both eyes	0.649	0.351	0.000
H54.2 Low vision, both eyes	0.649	0.351	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.648	0.352	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.647	0.353	0.000
M75.8 Other shoulder lesions	0.647	0.353	0.000
E03.5 Myxoedema coma	0.012	0.355	0.633
E03.4 Atrophy of thyroid (acquired)	0.012	0.355	0.633
E03.3 Postinfectious hypothyroidism	0.012	0.355	0.633
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.012	0.355	0.633
E03.1 Congenital hypothyroidism without goitre	0.012	0.355	0.633
E03.0 Congenital hypothyroidism with diffuse goitre	0.012	0.355	0.633
H62 Disorders of external ear in diseases classified elsewhere	0.644	0.356	0.000
J45.1 Nonallergic asthma	0.643	0.357	0.000
E07 Other disorders of thyroid	0.032	0.357	0.611
H34.9 Retinal vascular occlusion, unspecified	0.639	0.361	0.000
H34.0 Transient retinal artery occlusion	0.639	0.361	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.639	0.361	0.000
M79.1 Myalgia	0.638	0.362	0.000
H53.6 Night blindness	0.638	0.362	0.000
H53.5 Colour vision deficiencies	0.638	0.362	0.000
H53.3 Other disorders of binocular vision	0.638	0.362	0.000
M65 Synovitis and tenosynovitis	0.637	0.363	0.000
Chapter XX External causes of morbidity and mortality	0.637	0.363	0.000
M86 Osteomyelitis	0.636	0.364	0.000
E86 Volume depletion	0.635	0.365	0.000
E06 Thyroiditis	0.034	0.368	0.599
J30-J39 Other diseases of upper respiratory tract	0.630	0.370	0.000
F60-F69 Disorders of adult personality and behaviour	0.628	0.371	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.628	0.372	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.628	0.372	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.628	0.372	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.628	0.372	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.628	0.372	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.628	0.372	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.628	0.372	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.628	0.372	0.000
H74.1 Adhesive middle ear disease	0.628	0.372	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.625	0.375	0.000
M89 Other disorders of bone	0.624	0.376	0.000
H53.2 Diplopia	0.623	0.377	0.000
Q00-Q07 Congenital malformations of the nervous system	0.622	0.377	0.000
H90.0 Conductive hearing loss, bilateral	0.621	0.379	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.619	0.381	0.000
J60-J70 Lung diseases due to external agents	0.618	0.382	0.000
H43.2 Crystalline deposits in vitreous body	0.617	0.383	0.000
H43.0 Vitreous prolapse	0.617	0.383	0.000
H74.0 Tympanosclerosis	0.617	0.383	0.000
H61.1 Non-infective disorders of pinna	0.617	0.383	0.000
F41 Other anxiety disorders	0.617	0.383	0.000
J33 Nasal polyp	0.616	0.384	0.000
R41.3 Other amnesia	0.616	0.384	0.000
M10.96 Gout, unspecified (Lower leg)	0.616	0.384	0.000
Q27 Other congenital malformations of peripheral vascular system	0.615	0.385	0.000
R41.2 Retrograde amnesia	0.615	0.385	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.614	0.386	0.000
R32 Unspecified urinary incontinence	0.614	0.386	0.000
M71 Other bursopathies	0.614	0.386	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.614	0.386	0.000
R47-R49 Symptoms and signs involving speech and voice	0.614	0.386	0.000
M66 Spontaneous rupture of synovium and tendon	0.613	0.387	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.613	0.387	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.610	0.390	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.610	0.390	0.000
M11.2 Other chondrocalcinosis	0.610	0.390	0.000
H43.9 Disorder of vitreous body, unspecified	0.609	0.391	0.000
Q65 Congenital deformities of hip	0.609	0.391	0.000
M79.0 Rheumatism, unspecified	0.609	0.391	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.609	0.391	0.000
H73.1 Chronic myringitis	0.609	0.391	0.000
H73.0 Acute myringitis	0.609	0.391	0.000
M14.6 Neuropathic arthropathy	0.609	0.391	0.000
M72.9 Fibroblastic disorder, unspecified	0.607	0.393	0.000
M72.8 Other fibroblastic disorders	0.607	0.393	0.000
M72.6 Necrotizing fasciitis	0.607	0.393	0.000
M72.5 Fasciitis, not elsewhere classified	0.607	0.393	0.000
M72.4 Pseudosarcomatous fibromatosis	0.607	0.393	0.000
M72.3 Nodular fasciitis	0.607	0.393	0.000
M72.1 Knuckle pads	0.607	0.393	0.000
M10.4 Other secondary gout	0.607	0.393	0.000
M10.3 Gout due to impairment of renal function	0.607	0.393	0.000
M10.2 Drug-induced gout	0.607	0.393	0.000
M10.1 Lead-induced gout	0.607	0.393	0.000
M10.0 Idiopathic gout	0.607	0.393	0.000
Q61.2 Polycystic kidney, adult type	0.606	0.394	0.000
Q83 Congenital malformations of breast	0.605	0.395	0.000
F30-F39 Mood [affective] disorders	0.605	0.395	0.000
H66.4 Suppurative otitis media, unspecified	0.604	0.395	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.604	0.395	0.000
H66.0 Acute suppurative otitis media	0.604	0.395	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.604	0.396	0.000
Q64 Other congenital malformations of urinary system	0.604	0.396	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.604	0.396	0.000
Q66.3 Other congenital varus deformities of feet	0.603	0.397	0.000
Q24 Other congenital malformations of heart	0.601	0.399	0.000
H31.8 Other specified disorders of choroid	0.601	0.399	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.599	0.401	0.000
H61.0 Perichondritis of external ear	0.598	0.402	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.596	0.404	0.000
Q78 Other osteochondrodysplasias	0.596	0.404	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.596	0.404	0.000
Q75 Other congenital malformations of skull and face bones	0.596	0.404	0.000
Q74 Other congenital malformations of limb(s)	0.596	0.404	0.000
Q73 Reduction defects of unspecified limb	0.596	0.404	0.000
Q72 Reduction defects of lower limb	0.596	0.404	0.000
Q71 Reduction defects of upper limb	0.596	0.404	0.000
Q70 Syndactyly	0.596	0.404	0.000
Q69 Polydactyly	0.596	0.404	0.000
Q68 Other congenital musculoskeletal deformities	0.596	0.404	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.596	0.404	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.595	0.405	0.000
Q60.0 Renal agenesis, unilateral	0.595	0.405	0.000
M07 Psoriatic and enteropathic arthropathies	0.594	0.405	0.000
E53.9 Vitamin B deficiency, unspecified	0.594	0.405	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.594	0.406	0.000
J33.0 Polyp of nasal cavity	0.594	0.406	0.000
E61 Deficiency of other nutrient elements	0.593	0.407	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.593	0.407	0.000
J85 Abscess of lung and mediastinum	0.593	0.407	0.000
H61.9 Disorder of external ear, unspecified	0.592	0.408	0.000
M83 Adult osteomalacia	0.591	0.409	0.000
M40-M43 Deforming dorsopathies	0.590	0.410	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.589	0.411	0.000
R35 Polyuria	0.589	0.411	0.000
H74.4 Polyp of middle ear	0.588	0.412	0.000
H60.9 Otitis externa, unspecified	0.588	0.412	0.000
E55.0 Rickets, active	0.587	0.412	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.041	0.413	0.546
E00 Congenital iodine-deficiency syndrome	0.041	0.413	0.546
E02 Subclinical iodine-deficiency hypothyroidism	0.041	0.413	0.546
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.587	0.413	0.000
F70-F79 Mental retardation	0.587	0.413	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.586	0.414	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.586	0.414	0.000
R33 Retention of urine	0.586	0.414	0.000
M76.8 Other enthesopathies of lower limb, excluding foot	0.585	0.414	0.000
H31.9 Disorder of choroid, unspecified	0.583	0.416	0.000
H31.4 Choroidal detachment	0.583	0.416	0.000
H31.3 Choroidal haemorrhage and rupture	0.583	0.416	0.000
H31.2 Hereditary choroidal dystrophy	0.583	0.416	0.000
H31.1 Choroidal degeneration	0.583	0.416	0.000
M72.2 Plantar fascial fibromatosis	0.583	0.417	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.583	0.417	0.000
J09-J18 Influenza and pneumonia	0.583	0.417	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.582	0.418	0.000
M77.9 Enthesopathy, unspecified	0.580	0.420	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.580	0.420	0.000
E45 Retarded development following protein-energy malnutrition	0.580	0.420	0.000
E43 Unspecified severe protein-energy malnutrition	0.580	0.420	0.000
E42 Marasmic kwashiorkor	0.580	0.420	0.000
E41 Nutritional marasmus	0.580	0.420	0.000
E40 Kwashiorkor	0.580	0.420	0.000
Q63 Other congenital malformations of kidney	0.579	0.421	0.000
Q26 Congenital malformations of great veins	0.578	0.421	0.000
Q25 Congenital malformations of great arteries	0.578	0.421	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.578	0.421	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.578	0.421	0.000
M75.2 Bicipital tendinitis	0.578	0.422	0.000
Q85.9 Phakomatosis, unspecified	0.578	0.422	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.577	0.422	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.577	0.422	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.577	0.422	0.000
Y43 Primarily systemic agents	0.576	0.424	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.575	0.424	0.000
Q84 Other congenital malformations of integument	0.575	0.424	0.000
Q81 Epidermolysis bullosa	0.575	0.424	0.000
Q80 Congenital ichthyosis	0.575	0.424	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.574	0.425	0.000
Q23.0 Congenital stenosis of aortic valve	0.574	0.426	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.574	0.426	0.000
H70.9 Mastoiditis, unspecified	0.574	0.426	0.000
H70.2 Petrositis	0.574	0.426	0.000
H70.1 Chronic mastoiditis	0.574	0.426	0.000
H70.0 Acute mastoiditis	0.574	0.426	0.000
H60.4 Cholesteatoma of external ear	0.574	0.426	0.000
M10.94 Gout, unspecified (Hand)	0.574	0.426	0.000
R49 Voice disturbances	0.573	0.427	0.000
H93.9 Disorder of ear, unspecified	0.573	0.427	0.000
H35.8 Other specified retinal disorders	0.572	0.428	0.000
J41 Simple and mucopurulent chronic bronchitis	0.572	0.428	0.000
J06.9 Acute upper respiratory infection, unspecified	0.572	0.428	0.000
S00-S09 Injuries to the head	0.571	0.429	0.000
H92.2 Otorrhagia	0.571	0.429	0.000
Q76 Congenital malformations of spine and bony thorax	0.570	0.430	0.000
M13 Other arthritis	0.570	0.430	0.000
M82.1 Osteoporosis in endocrine disorders	0.569	0.431	0.000
E22.0 Acromegaly and pituitary gigantism	0.569	0.431	0.000
E20 Hypoparathyroidism	0.569	0.431	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.568	0.432	0.000
E65 Localised adiposity	0.568	0.432	0.000
E34 Other endocrine disorders	0.565	0.435	0.000
R45 Symptoms and signs involving emotional state	0.565	0.435	0.000
F41.2 Mixed anxiety and depressive disorder	0.565	0.435	0.000
H33 Retinal detachments and breaks	0.564	0.436	0.000
J45.8 Mixed asthma	0.563	0.437	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.562	0.437	0.000
M67 Other disorders of synovium and tendon	0.562	0.438	0.000
H61.3 Acquired stenosis of external ear canal	0.561	0.439	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.560	0.440	0.000
F02 Dementia in other diseases classified elsewhere	0.560	0.440	0.000
H44 Disorders of globe	0.559	0.441	0.000
Q61.3 Polycystic kidney, unspecified	0.559	0.441	0.000
J45.0 Predominantly allergic asthma	0.559	0.441	0.000
E53.1 Pyridoxine deficiency	0.558	0.442	0.000
E53.0 Riboflavin deficiency	0.558	0.442	0.000
H55-H59 Other disorders of eye and adnexa	0.557	0.443	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.557	0.443	0.000
M84 Disorders of continuity of bone	0.555	0.444	0.000
Q21 Congenital malformations of cardiac septa	0.555	0.445	0.000
E22.1 Hyperprolactinaemia	0.554	0.446	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.554	0.446	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.554	0.446	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.554	0.446	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.554	0.446	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.554	0.446	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.554	0.446	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.554	0.446	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.554	0.446	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.554	0.446	0.000
M11.9 Crystal arthropathy, unspecified	0.554	0.446	0.000
M11.8 Other specified crystal arthropathies	0.554	0.446	0.000
M11.1 Familial chondrocalcinosis	0.554	0.446	0.000
M11.0 Hydroxyapatite deposition disease	0.554	0.446	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.553	0.446	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.553	0.446	0.000
M14.4 Arthropathy in amyloidosis	0.553	0.446	0.000
M14.3 Lipoid dermatoarthritis	0.553	0.446	0.000
M14.2 Diabetic arthropathy	0.553	0.446	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.553	0.446	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.553	0.446	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.553	0.447	0.000
Q28 Other congenital malformations of circulatory system	0.552	0.447	0.000
E85 Amyloidosis	0.551	0.448	0.000
E24 Cushing's syndrome	0.550	0.450	0.000
Q89 Other congenital malformations, not elsewhere classified	0.550	0.450	0.000
R30 Pain associated with micturition	0.550	0.450	0.000
H93.1 Tinnitus	0.549	0.451	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.549	0.451	0.000
M06.38 Rheumatoid nodule (Other)	0.549	0.451	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.549	0.451	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.549	0.451	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations