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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9270227
log Bayes Factor = 253.321
Chromosome 6   position 32,556,699  (GRCh37) Explore rs9270227 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
Z93.2 Ileostomy status
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
J45 Asthma
0.000 0.000 1.000
C44.3 Skin of other and unspecified parts of face
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.001 0.999
K90 Intestinal malabsorption
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
K51.4 Pseudopolyposis of colon
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
K90-K93 Other diseases of the digestive system
0.000 0.002 0.998
K51.8 Other ulcerative colitis
0.998 0.002 0.000
K70-K77 Diseases of liver
0.000 0.003 0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.004 0.996
C44 Other malignant neoplasms of skin
0.995 0.005 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.006 0.994
K51.3 Ulcerative (chronic) rectosigmoiditis
0.993 0.007 0.000
E14.3 With ophthalmic complications
0.000 0.007 0.993
E11.1 With ketoacidosis
0.000 0.010 0.990
H30-H36 Disorders of choroid and retina
0.000 0.011 0.989
D64.9 Anaemia, unspecified
0.000 0.012 0.988
D60-D64 Aplastic and other anaemias
0.000 0.013 0.987
D64 Other anaemias
0.000 0.014 0.986
E05.9 Thyrotoxicosis, unspecified
0.000 0.014 0.986
K86 Other diseases of pancreas
0.000 0.016 0.984
E11.3 With ophthalmic complications
0.000 0.017 0.983
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.017 0.983
Chapter VII Diseases of the eye and adnexa
0.000 0.017 0.983
E10.5 With peripheral circulatory complications
0.000 0.017 0.983
L90.0 Lichen sclerosus et atrophicus
0.000 0.018 0.982
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.018 0.982
K74 Fibrosis and cirrhosis of liver
0.000 0.020 0.980
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.020 0.980
K75 Other inflammatory liver diseases
0.000 0.021 0.979
L90 Atrophic disorders of skin
0.000 0.021 0.979
J33 Nasal polyp
0.000 0.022 0.978
K75.4 Autoimmune hepatitis
0.000 0.025 0.975
J33.9 Nasal polyp, unspecified
0.000 0.025 0.975
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.027 0.973
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.027 0.973
K51.2 Ulcerative (chronic) proctitis
0.973 0.027 0.000
L40-L45 Papulosquamous disorders
0.000 0.028 0.972
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.030 0.970
L40 Psoriasis
0.000 0.031 0.969
G35-G37 Demyelinating diseases of the central nervous system
0.964 0.035 0.001
L40.9 Psoriasis, unspecified
0.000 0.036 0.964
K86.1 Other chronic pancreatitis
0.000 0.038 0.962
Chapter VIII Diseases of the ear and mastoid process
0.000 0.038 0.962
J43 Emphysema
0.000 0.039 0.961
J33.8 Other polyp of sinus
0.000 0.040 0.960
H60-H62 Diseases of external ear
0.000 0.040 0.960
H61 Other disorders of external ear
0.000 0.044 0.956
H43-H45 Disorders of vitreous body and globe
0.000 0.044 0.956
G37 Other demyelinating diseases of central nervous system
0.955 0.044 0.000
E10.8 With unspecified complications
0.000 0.045 0.955
D50-D53 Nutritional anaemias
0.000 0.048 0.952
H61.0 Perichondritis of external ear
0.000 0.048 0.952
E11.2 With renal complications
0.000 0.048 0.952
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.049 0.951
K86.0 Alcohol-induced chronic pancreatitis
0.000 0.050 0.950
J86 Pyothorax
0.000 0.050 0.950
J33.0 Polyp of nasal cavity
0.000 0.051 0.949
G37.9 Demyelinating disease of central nervous system, unspecified
0.949 0.051 0.000
H34 Retinal vascular occlusions
0.000 0.052 0.948
H43 Disorders of vitreous body
0.000 0.052 0.948
D50 Iron deficiency anaemia
0.000 0.058 0.942
D50.9 Iron deficiency anaemia, unspecified
0.000 0.060 0.940
J43.9 Emphysema, unspecified
0.000 0.061 0.939
J30-J39 Other diseases of upper respiratory tract
0.000 0.062 0.938
K90.9 Intestinal malabsorption, unspecified
0.000 0.062 0.938
K74.3 Primary biliary cirrhosis
0.000 0.064 0.936
C44.7 Skin of lower limb, including hip
0.935 0.065 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.930 0.070 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.071 0.929
E10.0 With coma
0.000 0.072 0.928
L80 Vitiligo
0.000 0.072 0.928
K51.5 Mucosal proctocolitis
0.925 0.075 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.080 0.920
L92.0 Granuloma annulare
0.000 0.084 0.916
H43.3 Other vitreous opacities
0.000 0.084 0.916
J95-J99 Other diseases of the respiratory system
0.000 0.084 0.916
E13 Other specified diabetes mellitus
0.000 0.085 0.915
J46 Status asthmaticus
0.000 0.088 0.912
E03.8 Other specified hypothyroidism
0.000 0.090 0.910
E11.5 With peripheral circulatory complications
0.000 0.091 0.909
K86.3 Pseudocyst of pancreas
0.000 0.097 0.903
E10.2 With renal complications
0.000 0.098 0.902
C44.1 Skin of eyelid, including canthus
0.899 0.101 0.000
H34.8 Other retinal vascular occlusions
0.000 0.101 0.899
D86 Sarcoidosis
0.000 0.101 0.899
K72 Hepatic failure, not elsewhere classified
0.000 0.103 0.897
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.104 0.896
E11.6 With other specified complications
0.000 0.104 0.896
E06 Thyroiditis
0.000 0.110 0.890
J86.9 Pyothorax without fistula
0.000 0.113 0.887
J86.0 Pyothorax with fistula
0.000 0.119 0.881
K86.2 Cyst of pancreas
0.000 0.123 0.877
E83 Disorders of mineral metabolism
0.871 0.129 0.000
J98 Other respiratory disorders
0.000 0.130 0.870
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.000 0.130 0.870
H43.8 Other disorders of vitreous body
0.000 0.134 0.866
K74.5 Biliary cirrhosis, unspecified
0.000 0.136 0.864
C44.5 Skin of trunk
0.863 0.137 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.140 0.860
K74.6 Other and unspecified cirrhosis of liver
0.000 0.142 0.858
H60 Otitis externa
0.000 0.142 0.858
E13.9 Without complications
0.000 0.142 0.858
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.143 0.857
E10.6 With other specified complications
0.000 0.145 0.855
K86.8 Other specified diseases of pancreas
0.000 0.147 0.853
E14.8 With unspecified complications
0.000 0.149 0.851
E83.3 Disorders of phosphorus metabolism
0.847 0.153 0.000
E24 Cushing's syndrome
0.000 0.159 0.841
E27 Other disorders of adrenal gland
0.000 0.160 0.840
E16.1 Other hypoglycaemia
0.000 0.164 0.836
L40.0 Psoriasis vulgaris
0.000 0.165 0.835
E07 Other disorders of thyroid
0.000 0.169 0.831
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.172 0.828
H53-H54 Visual disturbances and blindness
0.000 0.173 0.827
K73 Chronic hepatitis, not elsewhere classified
0.000 0.175 0.825
K72.0 Acute and subacute hepatic failure
0.000 0.178 0.822
E06.3 Autoimmune thyroiditis
0.000 0.192 0.808
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.192 0.808
H43.1 Vitreous haemorrhage
0.000 0.194 0.806
C44.0 Skin of lip
0.800 0.200 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.200 0.800
K82 Other diseases of gallbladder
0.000 0.200 0.800
E21.0 Primary hyperparathyroidism
0.000 0.201 0.799
E14.6 With other specified complications
0.000 0.202 0.798
E65-E68 Obesity and other hyperalimentation
0.000 0.204 0.796
D86.8 Sarcoidosis of other and combined sites
0.000 0.204 0.796
L40.8 Other psoriasis
0.000 0.206 0.794
L10-L14 Bullous disorders
0.000 0.208 0.792
C44.4 Skin of scalp and neck
0.790 0.210 0.000
H60.9 Otitis externa, unspecified
0.000 0.212 0.788
J98.4 Other disorders of lung
0.000 0.212 0.788
E40-E46 Malnutrition
0.000 0.212 0.788
H35 Other retinal disorders
0.000 0.213 0.787
H61.3 Acquired stenosis of external ear canal
0.000 0.216 0.784
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.219 0.781
H61.8 Other specified disorders of external ear
0.000 0.224 0.776
H54 Blindness and low vision
0.000 0.225 0.775
H34.2 Other retinal artery occlusions
0.000 0.229 0.771
L40.1 Generalised pustular psoriasis
0.000 0.240 0.760
E14.2 Withrenal complications
0.000 0.243 0.757
K74.0 Hepatic fibrosis
0.000 0.245 0.755
E14.5 With peripheral circulatory complications
0.000 0.245 0.755
E14.4 With neurological complications
0.000 0.249 0.751
E21.3 Hyperparathyroidism, unspecified
0.000 0.250 0.750
H54.7 Unspecified visual loss
0.000 0.250 0.750
J33.1 Polypoid sinus degeneration
0.000 0.250 0.750
J85 Abscess of lung and mediastinum
0.000 0.252 0.748
C44.6 Skin of upper limb, including shoulder
0.745 0.255 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.260 0.740
J44 Other chronic obstructive pulmonary disease
0.000 0.260 0.740
L94 Other localised connective tissue disorders
0.000 0.261 0.739
J37 Chronic laryngitis and laryngotracheitis
0.000 0.262 0.738
D55-D59 Haemolytic anaemias
0.000 0.263 0.737
H61.1 Non-infective disorders of pinna
0.000 0.266 0.734
J42 Unspecified chronic bronchitis
0.000 0.270 0.730
E24.9 Cushing's syndrome, unspecified
0.000 0.271 0.729
E07.9 Disorder of thyroid, unspecified
0.000 0.279 0.721
G37.8 Other specified demyelinating diseases of central nervous system
0.720 0.280 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.717 0.282 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
H35.2 Other proliferative retinopathy
0.000 0.283 0.717
K90.3 Pancreatic steatorrhoea
0.000 0.283 0.716
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.283 0.716
K90.1 Tropical sprue
0.000 0.283 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.284 0.715
K77 Liver disorders in diseases classified elsewhere
0.000 0.285 0.715
J98.9 Respiratory disorder, unspecified
0.000 0.285 0.715
D86.1 Sarcoidosis of lymph nodes
0.000 0.286 0.714
C44.8 Overlapping lesion of skin
0.713 0.286 0.000
J98.6 Disorders of diaphragm
0.000 0.287 0.713
D80 Immunodeficiency with predominantly antibody defects
0.000 0.287 0.713
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.287 0.713
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.287 0.712
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.289 0.711
J45.1 Nonallergic asthma
0.000 0.289 0.710
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.291 0.709
E83.9 Disorder of mineral metabolism, unspecified
0.709 0.291 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.292 0.708
G36 Other acute disseminated demyelination
0.706 0.293 0.001
D64.4 Congenital dyserythropoietic anaemia
0.000 0.293 0.707
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.293 0.707
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.293 0.707
D64.0 Hereditary sideroblastic anaemia
0.000 0.293 0.707
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.294 0.706
E24.0 Pituitary-dependent Cushing's disease
0.000 0.294 0.706
H43.2 Crystalline deposits in vitreous body
0.000 0.294 0.706
H34.9 Retinal vascular occlusion, unspecified
0.000 0.295 0.705
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.296 0.704
K74.4 Secondary biliary cirrhosis
0.000 0.297 0.703
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.297 0.703
K82.8 Other specified diseases of gallbladder
0.000 0.297 0.703
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.298 0.702
L87 Transepidermal elimination disorders
0.000 0.298 0.702
L86 Keratoderma in diseases classified elsewhere
0.000 0.298 0.702
K75.2 Nonspecific reactive hepatitis
0.000 0.298 0.702
K75.1 Phlebitis of portal vein
0.000 0.298 0.702
L90.9 Atrophic disorder of skin, unspecified
0.000 0.298 0.702
L90.6 Striae atrophicae
0.000 0.298 0.702
L90.4 Acrodermatitis chronica atrophicans
0.000 0.298 0.702
L90.3 Atrophoderma of Pasini and Pierini
0.000 0.298 0.702
L90.2 Anetoderma of Jadassohn-Pellizzari
0.000 0.298 0.702
L90.1 Anetoderma of Schweninger-Buzzi
0.000 0.298 0.702
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.302 0.698
L44 Other papulosquamous disorders
0.000 0.303 0.697
L41 Parapsoriasis
0.000 0.303 0.697
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.303 0.697
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.303 0.697
L40.4 Guttate psoriasis
0.000 0.305 0.695
L40.3 Pustulosis palmaris et plantaris
0.000 0.305 0.695
L40.2 Acrodermatitis continua
0.000 0.305 0.695
J43.2 Centrilobular emphysema
0.000 0.307 0.693
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.691 0.309 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.309 0.691
J45.0 Predominantly allergic asthma
0.000 0.310 0.690
H60.3 Other infective otitis externa
0.000 0.311 0.689
J43.1 Panlobular emphysema
0.000 0.311 0.689
J43.0 MacLeod's syndrome
0.000 0.311 0.689
H62 Disorders of external ear in diseases classified elsewhere
0.000 0.312 0.688
E66 Obesity
0.000 0.312 0.688
L13 Other bullous disorders
0.000 0.312 0.688
D53 Other nutritional anaemias
0.000 0.312 0.687
J98.8 Other specified respiratory disorders
0.000 0.313 0.687
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.315 0.685
G37.5 Concentric sclerosis [Balo]
0.685 0.315 0.000
G37.4 Subacute necrotising myelitis
0.685 0.315 0.000
G37.2 Central pontine myelinolysis
0.685 0.315 0.000
G37.1 Central demyelination of corpus callosum
0.685 0.315 0.000
G37.0 Diffuse sclerosis
0.685 0.315 0.000
K82.9 Disease of gallbladder, unspecified
0.000 0.315 0.685
J41 Simple and mucopurulent chronic bronchitis
0.000 0.317 0.683
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.318 0.682
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.318 0.682
H30 Chorioretinal inflammation
0.000 0.318 0.681
H34.0 Transient retinal artery occlusion
0.000 0.320 0.679
H43.0 Vitreous prolapse
0.000 0.321 0.679
K71 Toxic liver disease
0.000 0.323 0.677
J45.8 Mixed asthma
0.000 0.323 0.676
E29 Testicular dysfunction
0.000 0.324 0.676
E11.8 With unspecified complications
0.000 0.324 0.676
D50.1 Sideropenic dysphagia
0.000 0.325 0.675
H35.0 Background retinopathy and retinal vascular changes
0.000 0.327 0.673
H34.1 Central retinal artery occlusion
0.000 0.327 0.673
H80-H83 Diseases of inner ear
0.000 0.328 0.672
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.334 0.666
E32 Diseases of thymus
0.000 0.334 0.666
E31 Polyglandular dysfunction
0.000 0.334 0.666
E30 Disorders of puberty, not elsewhere classified
0.000 0.334 0.666
K72.9 Hepatic failure, unspecified
0.000 0.335 0.665
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.337 0.663
L43 Lichen planus
0.000 0.339 0.661
E05.8 Other thyrotoxicosis
0.000 0.340 0.660
D82 Immunodeficiency associated with other major defects
0.000 0.340 0.659
D81 Combined immunodeficiencies
0.000 0.340 0.659
E66.9 Obesity, unspecified
0.000 0.341 0.659
H54.0 Blindness, both eyes
0.000 0.343 0.657
H60.8 Other otitis externa
0.000 0.343 0.657
J96 Respiratory failure, not elsewhere classified
0.000 0.343 0.656
E13.8 With unspecified complications
0.000 0.344 0.656
E13.7 With multiple complications
0.000 0.344 0.656
E13.6 With other specified complications
0.000 0.344 0.656
E13.5 With peripheral circulatory complications
0.000 0.344 0.656
E13.4 With neurological complications
0.000 0.344 0.656
E13.2 With renal complications
0.000 0.344 0.656
E13.1 With ketoacidosis
0.000 0.344 0.656
E13.0 With coma
0.000 0.344 0.656
D83 Common variable immunodeficiency
0.000 0.345 0.655
H61.9 Disorder of external ear, unspecified
0.000 0.347 0.653
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.348 0.652
E03.1 Congenital hypothyroidism without goitre
0.000 0.349 0.651
E06.9 Thyroiditis, unspecified
0.000 0.352 0.648
J98.2 Interstitial emphysema
0.000 0.352 0.648
E20 Hypoparathyroidism
0.000 0.353 0.646
D86.3 Sarcoidosis of skin
0.000 0.356 0.644
J95.0 Tracheostomy malfunction
0.000 0.356 0.644
E21.4 Other specified disorders of parathyroid gland
0.000 0.357 0.643
J85.2 Abscess of lung without pneumonia
0.000 0.358 0.642
D62 Acute posthaemorrhagic anaemia
0.000 0.358 0.642
K75.8 Other specified inflammatory liver diseases
0.000 0.360 0.640
E06.5 Other chronic thyroiditis
0.000 0.362 0.638
E06.4 Drug-induced thyroiditis
0.000 0.362 0.638
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.362 0.638
E06.1 Subacute thyroiditis
0.000 0.362 0.638
E06.0 Acute thyroiditis
0.000 0.362 0.638
E13.3 With ophthalmic complications
0.000 0.363 0.637
D50.8 Other iron deficiency anaemias
0.000 0.363 0.637
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.363 0.637
E46 Unspecified protein-energy malnutrition
0.000 0.365 0.635
K72.1 Chronic hepatic failure
0.000 0.366 0.634
Chapter IX Diseases of the circulatory system
0.000 0.371 0.629
K90.8 Other intestinal malabsorption
0.000 0.372 0.627
J43.8 Other emphysema
0.000 0.372 0.627
H60.5 Acute otitis externa, non-infective
0.000 0.373 0.627
H35.6 Retinal haemorrhage
0.000 0.375 0.625
E83.8 Other disorders of mineral metabolism
0.624 0.376 0.000
E83.2 Disorders of zinc metabolism
0.624 0.376 0.000
E83.0 Disorders of copper metabolism
0.624 0.376 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.624 0.376 0.000
J98.3 Compensatory emphysema
0.000 0.376 0.624
C44.2 Skin of ear and external auricular canal
0.624 0.376 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.377 0.623
D64.3 Other sideroblastic anaemias
0.000 0.377 0.623
I10-I15 Hypertensive diseases
0.000 0.377 0.623
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.378 0.622
H35.8 Other specified retinal disorders
0.000 0.384 0.616
H60.2 Malignant otitis externa
0.000 0.385 0.615
D58 Other hereditary haemolytic anaemias
0.000 0.385 0.615
L13.0 Dermatitis herpetiformis
0.000 0.387 0.613
K82.3 Fistula of gallbladder
0.000 0.387 0.613
K73.9 Chronic hepatitis, unspecified
0.000 0.389 0.611
L90.8 Other atrophic disorders of skin
0.000 0.395 0.605
H54.2 Low vision, both eyes
0.000 0.396 0.604
E24.8 Other Cushing's syndrome
0.000 0.397 0.603
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.397 0.603
E24.3 Ectopic ACTH syndrome
0.000 0.397 0.603
E24.2 Drug-induced Cushing's syndrome
0.000 0.397 0.603
E24.1 Nelson's syndrome
0.000 0.397 0.603
E27.5 Adrenomedullary hyperfunction
0.000 0.397 0.603
E27.0 Other adrenocortical overactivity
0.000 0.397 0.603
H60.4 Cholesteatoma of external ear
0.000 0.398 0.602
K82.2 Perforation of gallbladder
0.000 0.401 0.599
E11.0 With coma
0.000 0.403 0.597
E07.1 Dyshormogenetic goitre
0.000 0.404 0.596
E07.0 Hypersecretion of calcitonin
0.000 0.404 0.596
E21.2 Other hyperparathyroidism
0.000 0.405 0.595
J37.0 Chronic laryngitis
0.000 0.405 0.595
L94.2 Calcinosis cutis
0.000 0.406 0.594
I10 Essential (primary) hypertension
0.000 0.408 0.592
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.408 0.592
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.408 0.592
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.408 0.592
K50-K52 Noninfective enteritis and colitis
0.163 0.408 0.429
H43.9 Disorder of vitreous body, unspecified
0.000 0.409 0.591
K75.9 Inflammatory liver disease, unspecified
0.000 0.410 0.590
E27.8 Other specified disorders of adrenal gland
0.000 0.411 0.589
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.412 0.588
H35.5 Hereditary retinal dystrophy
0.000 0.415 0.585
H54.1 Blindness, one eye, low vision, other eye
0.000 0.416 0.584
Q80-Q89 Other congenital malformations
0.000 0.417 0.583
E28 Ovarian dysfunction
0.000 0.425 0.575
H35.4 Peripheral retinal degeneration
0.000 0.425 0.575
E25 Adrenogenital disorders
0.000 0.427 0.573
E07.8 Other specified disorders of thyroid
0.000 0.428 0.572
E67 Other hyperalimentation
0.000 0.429 0.571
E68 Sequelae of hyperalimentation
0.000 0.429 0.571
K82.0 Obstruction of gallbladder
0.000 0.429 0.571
L94.9 Localised connective tissue disorder, unspecified
0.000 0.431 0.569
L10 Pemphigus
0.000 0.432 0.568
L14 Bullous disorders in diseases classified elsewhere
0.000 0.432 0.568
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.433 0.567
I15 Secondary hypertension
0.000 0.433 0.567
Q60-Q64 Congenital malformations of the urinary system
0.000 0.434 0.566
L11 Other acantholytic disorders
0.000 0.434 0.566
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.435 0.565
E45 Retarded development following protein-energy malnutrition
0.000 0.435 0.565
E43 Unspecified severe protein-energy malnutrition
0.000 0.435 0.565
E42 Marasmic kwashiorkor
0.000 0.435 0.565
E41 Nutritional marasmus
0.000 0.435 0.565
E40 Kwashiorkor
0.000 0.435 0.565
H35.1 Retinopathy of prematurity
0.000 0.436 0.564
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.437 0.563
E26 Hyperaldosteronism
0.000 0.439 0.561
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.439 0.561
H80 Otosclerosis
0.000 0.440 0.560
E83.4 Disorders of magnesium metabolism
0.559 0.441 0.000
H54.3 Unqualified visual loss, both eyes
0.000 0.444 0.556
H54.5 Low vision, one eye
0.000 0.444 0.556
H60.1 Cellulitis of external ear
0.000 0.445 0.554
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.448 0.552
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.449 0.551
E27.9 Disorder of adrenal gland, unspecified
0.000 0.449 0.551
J85.0 Gangrene and necrosis of lung
0.000 0.449 0.551
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.451 0.549
D86.0 Sarcoidosis of lung
0.000 0.454 0.546
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.455 0.544
J36 Peritonsillar abscess
0.000 0.458 0.542
E83.5 Disorders of calcium metabolism
0.541 0.459 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.461 0.539
J85.3 Abscess of mediastinum
0.000 0.464 0.536
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.466 0.534
L84 Corns and callosities
0.000 0.468 0.532
L94.6 Ainhum
0.000 0.470 0.530
L94.5 Poikiloderma vasculare atrophicans
0.000 0.470 0.530
L94.4 Gottron's papules
0.000 0.470 0.530
L94.3 Sclerodactyly
0.000 0.470 0.530
L94.1 Linear scleroderma
0.000 0.470 0.530
J37.1 Chronic laryngotracheitis
0.000 0.471 0.529
D57 Sickle-cell disorders
0.000 0.472 0.528
D55 Anaemia due to enzyme disorders
0.000 0.472 0.528
Q85 Phakomatoses, not elsewhere classified
0.000 0.474 0.526
K81 Cholecystitis
0.000 0.475 0.525
I12 Hypertensive renal disease
0.000 0.477 0.523
G36.0 Neuromyelitis optica [Devic]
0.522 0.477 0.001
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.481 0.519
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.484 0.515
Q61 Cystic kidney disease
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
P90-P96 Other disorders originating in the perinatal period
0.000 0.486 0.514
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.000 0.486 0.514
P75-P78 Digestive system disorders of fetus and newborn
0.000 0.486 0.514
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.000 0.486 0.514
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.000 0.486 0.514
P35-P39 Infections specific to the perinatal period
0.000 0.486 0.514
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.000 0.486 0.514
P10-P15 Birth trauma
0.000 0.486 0.514
P05-P08 Disorders related to length of gestation and fetal growth
0.000 0.486 0.514
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.000 0.486 0.514
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.486 0.514
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.487 0.513
K93.1 Megacolon in Chagas' disease
0.000 0.487 0.513
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.487 0.513
D51 Vitamin B12 deficiency anaemia
0.000 0.487 0.513
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.487 0.512
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.487 0.512
Q89 Other congenital malformations, not elsewhere classified
0.000 0.487 0.512
L81 Other disorders of pigmentation
0.000 0.488 0.512
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.488 0.511
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.488 0.511
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.488 0.511
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.488 0.511
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.488 0.511
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.488 0.511
J95.5 Postprocedural subglottic stenosis
0.000 0.490 0.510
J95.4 Mendelson's syndrome
0.000 0.490 0.510
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.490 0.510
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.490 0.510
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.490 0.510
I85 Oesophageal varices
0.000 0.490 0.510
H60.0 Abscess of external ear
0.000 0.491 0.509
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.491 0.509
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.491 0.509
D58.0 Hereditary spherocytosis
0.000 0.492 0.508
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.492 0.507
D60.8 Other acquired pure red cell aplasias
0.000 0.492 0.507

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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