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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs241454
log Bayes Factor = 114.601
Chromosome 6   position 32,796,144  (GRCh37) Explore rs241454 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
I21 Acute myocardial infarction
0.997 0.003 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
I21.9 Acute myocardial infarction, unspecified
0.996 0.004 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.996 0.004 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
I25.9 Chronic ischaemic heart disease, unspecified
0.994 0.006 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
I25.2 Old myocardial infarction
0.990 0.010 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.010 0.990
E10.4 With neurological complications
0.000 0.012 0.988
M07.39 Other psoriatic arthropathies (Site unspecified)
0.986 0.014 0.000
M07.3 Other psoriatic arthropathies
0.986 0.014 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.982 0.018 0.000
I24 Other acute ischaemic heart diseases
0.978 0.022 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.024 0.976
E07 Other disorders of thyroid
0.000 0.056 0.944
I24.8 Other forms of acute ischaemic heart disease
0.944 0.056 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.939 0.061 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.914 0.086 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.912 0.088 0.000
E10.0 With coma
0.000 0.089 0.911
C44 Other malignant neoplasms of skin
0.909 0.091 0.000
C44.2 Skin of ear and external auricular canal
0.908 0.092 0.000
E10.8 With unspecified complications
0.000 0.098 0.902
E07.9 Disorder of thyroid, unspecified
0.000 0.104 0.896
E10.2 With renal complications
0.000 0.107 0.893
I24.9 Acute ischaemic heart disease, unspecified
0.888 0.112 0.000
C44.3 Skin of other and unspecified parts of face
0.879 0.121 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.871 0.129 0.000
C82.0 Small cleaved cell, follicular
0.871 0.129 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.865 0.135 0.000
E14 Unspecified diabetes mellitus
0.000 0.136 0.864
C44.7 Skin of lower limb, including hip
0.859 0.141 0.000
L40.1 Generalised pustular psoriasis
0.857 0.143 0.000
C44.4 Skin of scalp and neck
0.857 0.143 0.000
E10.6 With other specified complications
0.000 0.146 0.854
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.852 0.148 0.000
I23 Certain current complications following acute myocardial infarction
0.850 0.150 0.000
J45 Asthma
0.000 0.153 0.847
E40-E46 Malnutrition
0.000 0.156 0.844
I25.1 Atherosclerotic heart disease
0.840 0.160 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.161 0.839
L40.0 Psoriasis vulgaris
0.831 0.169 0.000
I25.3 Aneurysm of heart
0.817 0.183 0.000
L40.4 Guttate psoriasis
0.816 0.183 0.000
J45.0 Predominantly allergic asthma
0.000 0.184 0.816
L40-L45 Papulosquamous disorders
0.810 0.190 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.797 0.203 0.000
E14.3 With ophthalmic complications
0.000 0.213 0.787
E16.1 Other hypoglycaemia
0.000 0.218 0.782
C44.0 Skin of lip
0.775 0.225 0.000
E10.5 With peripheral circulatory complications
0.000 0.232 0.768
L40.8 Other psoriasis
0.766 0.234 0.000
I22 Subsequent myocardial infarction
0.766 0.234 0.000
C82.3 Follicular lymphoma grade IIIa
0.751 0.249 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.748 0.252 0.000
I25.5 Ischaemic cardiomyopathy
0.745 0.255 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.739 0.261 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.264 0.736
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.733 0.266 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.268 0.732
C44.5 Skin of trunk
0.731 0.269 0.000
E07.8 Other specified disorders of thyroid
0.000 0.274 0.726
I25.0 Atherosclerotic cardiovascular disease, so described
0.724 0.276 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.723 0.277 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.716
I21.X Presumed acute myicardial infaction (unconfirmed)
0.715 0.285 0.000
C82.2 Large cell, follicular
0.715 0.285 0.000
K90 Intestinal malabsorption
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
M07.38 Other psoriatic arthropathies (Other)
0.707 0.293 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.707 0.293 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.707 0.293 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.707 0.293 0.000
E05.8 Other thyrotoxicosis
0.000 0.302 0.698
E03.8 Other specified hypothyroidism
0.000 0.306 0.694
M07 Psoriatic and enteropathic arthropathies
0.693 0.307 0.000
I20 Angina pectoris
0.688 0.312 0.000
L43 Lichen planus
0.688 0.312 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.681 0.318 0.000
E07.1 Dyshormogenetic goitre
0.000 0.323 0.677
E07.0 Hypersecretion of calcitonin
0.000 0.323 0.677
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.676 0.324 0.000
E14.9 Without complications
0.000 0.324 0.676
C82.4 Follicular lymphoma grade IIIb
0.659 0.341 0.000
C82.6 Cutaneous follicle centre lymphoma
0.654 0.346 0.000
C82.5 Diffuse follicle centre lymphoma
0.654 0.346 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.653 0.347 0.000
C44.8 Overlapping lesion of skin
0.652 0.348 0.000
E14.8 With unspecified complications
0.000 0.353 0.647
I24.1 Dressler's syndrome
0.641 0.359 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.639 0.361 0.000
L42 Pityriasis rosea
0.630 0.370 0.000
I23.8 Other current complications following acute myocardial infarction
0.629 0.371 0.000
E14.5 With peripheral circulatory complications
0.000 0.373 0.627
E14.7 With multiple complications
0.000 0.381 0.619
E14.2 Withrenal complications
0.000 0.381 0.619
E14.0 With coma
0.000 0.381 0.619
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.383 0.617
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.383 0.617
L43.9 Lichen planus, unspecified
0.615 0.385 0.000
E14.6 With other specified complications
0.000 0.388 0.611
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.609 0.390 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.609 0.390 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.609 0.390 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.609 0.390 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.609 0.390 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.609 0.390 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.608 0.391 0.000
I20.0 Unstable angina
0.608 0.392 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.608 0.392 0.000
J45.8 Mixed asthma
0.000 0.393 0.607
J45.1 Nonallergic asthma
0.000 0.393 0.607
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.395 0.605
E45 Retarded development following protein-energy malnutrition
0.000 0.395 0.605
E43 Unspecified severe protein-energy malnutrition
0.000 0.395 0.605
E42 Marasmic kwashiorkor
0.000 0.395 0.605
E41 Nutritional marasmus
0.000 0.395 0.605
E40 Kwashiorkor
0.000 0.395 0.605
I25.4 Coronary artery aneurysm
0.599 0.400 0.000
I20.1 Angina pectoris with documented spasm
0.598 0.402 0.000
K90.8 Other intestinal malabsorption
0.000 0.407 0.593
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.582 0.418 0.000
L44 Other papulosquamous disorders
0.581 0.419 0.000
L41 Parapsoriasis
0.581 0.419 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.581 0.419 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.569 0.431 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.567 0.433 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.566 0.434 0.000
C85.1 B-cell lymphoma, unspecified
0.564 0.436 0.000
E14.1 With ketoacidosis
0.000 0.442 0.558
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.558 0.442 0.000
T43.2 Other and unspecified antidepressants
0.553 0.447 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.449 0.551
T42.4 Benzodiazepines
0.550 0.450 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.550 0.450 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.542 0.458 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.532 0.468 0.000
F41 Other anxiety disorders
0.531 0.469 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.528 0.472 0.000
E50-E64 Other nutritional deficiencies
0.000 0.475 0.525
Chapter II Neoplasms
0.525 0.475 0.000
Chapter V Mental and behavioural disorders
0.523 0.477 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.523 0.477 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.520 0.480 0.000
F60-F69 Disorders of adult personality and behaviour
0.519 0.481 0.000
F60 Specific personality disorders
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
K90.3 Pancreatic steatorrhoea
0.000 0.488 0.512
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.488 0.512
K90.1 Tropical sprue
0.000 0.488 0.512
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.503 0.497 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.497 0.503
E14.4 With neurological complications
0.000 0.500 0.499
C90 Multiple myeloma and malignant plasma cell neoplasms
0.499 0.501 0.000
M07.6 Other enteropathic arthropathies
0.497 0.503 0.000
M07.5 Arthropathy in ulcerative colitis
0.497 0.503 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.497 0.503 0.000
M07.2 Psoriatic spondylitis
0.497 0.503 0.000
M07.1 Arthritis mutilans
0.497 0.503 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.497 0.503 0.000
I22.8 Subsequent myocardial infarction of other sites
0.496 0.504 0.000
L43.3 Subacute (active) lichen planus
0.493 0.507 0.000
L43.2 Lichenoid drug reaction
0.493 0.507 0.000
L43.1 Bullous lichen planus
0.493 0.507 0.000
L43.0 Hypertrophic lichen planus
0.493 0.507 0.000
C95 Leukaemia of unspecified cell type
0.491 0.509 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.484 0.516 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.484 0.516 0.000
F30-F39 Mood [affective] disorders
0.483 0.517 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.517 0.483
M05-M14 Inflammatory polyarthropathies
0.482 0.518 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.480 0.520 0.000
F60.9 Personality disorder, unspecified
0.479 0.521 0.000
F60.3 Emotionally unstable personality disorder
0.479 0.521 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.477 0.523 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.476 0.524 0.000
E13 Other specified diabetes mellitus
0.000 0.526 0.474
# Top node
0.472 0.528 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.468 0.532 0.000
F33 Recurrent depressive disorder
0.462 0.538 0.000
Chapter IX Diseases of the circulatory system
0.462 0.538 0.000
C73 Malignant neoplasm of thyroid gland
0.459 0.541 0.000
M65-M68 Disorders of synovium and tendon
0.457 0.543 0.000
F41.3 Other mixed anxiety disorders
0.456 0.544 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.455 0.545 0.000
L43.8 Other lichen planus
0.454 0.546 0.000
F41.1 Generalised anxiety disorder
0.452 0.548 0.000
M67 Other disorders of synovium and tendon
0.450 0.550 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.450 0.550 0.000
F69 Unspecified disorder of adult personality and behaviour
0.448 0.552 0.000
T42.1 Iminostilbenes
0.446 0.554 0.000
F48 Other neurotic disorders
0.444 0.556 0.000
M80-M85 Disorders of bone density and structure
0.443 0.557 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.442 0.558 0.000
F30 Manic episode
0.442 0.558 0.000
M60-M63 Disorders of muscles
0.441 0.559 0.000
E53 Deficiency of other B group vitamins
0.000 0.563 0.437
C93 Monocytic leukaemia
0.437 0.563 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.436 0.564 0.000
C94 Other leukaemias of specified cell type
0.436 0.564 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.435 0.565 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.566 0.434
E44.0 Moderate protein-energy malnutrition
0.000 0.566 0.434
L57 Skin changes due to chronic exposure to nonionising radiation
0.434 0.566 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.433 0.567 0.000
F44 Dissociative [conversion] disorders
0.431 0.569 0.000
M85 Other disorders of bone density and structure
0.427 0.573 0.000
C86 Other specified types of T/NK-cell lymphoma
0.426 0.574 0.000
M67.8 Other specified disorders of synovium and tendon
0.426 0.574 0.000
F41.8 Other specified anxiety disorders
0.424 0.576 0.000
F60.5 Anankastic personality disorder
0.424 0.576 0.000
M62 Other disorders of muscle
0.424 0.576 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.424 0.576 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.422 0.578 0.000
F45 Somatoform disorders
0.421 0.579 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.420 0.579 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.418 0.582 0.000
C85.0 Lymphosarcoma
0.418 0.582 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.417 0.583 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.417 0.583 0.000
L41.9 Parapsoriasis, unspecified
0.416 0.583 0.000
L41.8 Other parapsoriasis
0.416 0.583 0.000
L41.5 Retiform parapsoriasis
0.416 0.583 0.000
L41.4 Large plaque parapsoriasis
0.416 0.583 0.000
L41.3 Small plaque parapsoriasis
0.416 0.583 0.000
L41.2 Lymphomatoid papulosis
0.416 0.583 0.000
L41.1 Pityriasis lichenoides chronica
0.416 0.583 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.416 0.583 0.000
L44.9 Papulosquamous disorder, unspecified
0.416 0.583 0.000
L44.8 Other specified papulosquamous disorders
0.416 0.583 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.416 0.583 0.000
L44.3 Lichen ruber moniliformis
0.416 0.583 0.000
L44.2 Lichen striatus
0.416 0.583 0.000
L44.1 Lichen nitidus
0.416 0.583 0.000
L44.0 Pityriasis rubra pilaris
0.416 0.583 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.415 0.584 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.415 0.585 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.414 0.586 0.000
L57.0 Actinic keratosis
0.412 0.588 0.000
E06 Thyroiditis
0.000 0.588 0.411
M67.2 Synovial hypertrophy, not elsewhere classified
0.411 0.589 0.000
C74 Malignant neoplasm of adrenal gland
0.411 0.589 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.411 0.589 0.000
C44.1 Skin of eyelid, including canthus
0.410 0.590 0.000
F43 Reaction to severe stress, and adjustment disorders
0.409 0.591 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.409 0.591 0.000
M85.8 Other specified disorders of bone density and structure
0.408 0.592 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.408 0.592 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.408 0.592 0.000
M70-M79 Other soft tissue disorders
0.408 0.592 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.407 0.593 0.000
F60.8 Other specific personality disorders
0.407 0.593 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.406 0.594 0.000
T42.3 Barbiturates
0.406 0.594 0.000
T42.2 Succinimides and oxazolidinediones
0.406 0.594 0.000
T42.0 Hydantoin derivatives
0.406 0.594 0.000
T43.9 Psychotropic drug, unspecified
0.406 0.594 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.406 0.594 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.402 0.598 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.402 0.598 0.000
C95.9 Leukaemia, unspecified
0.400 0.600 0.000
T50.7 Analeptics and opioid receptor antagonists
0.400 0.600 0.000
T50.5 Appetite depressants
0.400 0.600 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.400 0.600 0.000
T50.1 Loop [high-ceiling] diuretics
0.400 0.600 0.000
T50.0 Mineralocorticoids and their antagonists
0.400 0.600 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.400 0.600 0.000
C90.2 Plasmacytoma, extramedullary
0.397 0.603 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.397 0.603 0.000
C90.0 Multiple myeloma
0.395 0.605 0.000
M62.8 Other specified disorders of muscle
0.394 0.606 0.000
T50.8 Diagnostic agents
0.394 0.606 0.000
F70-F79 Mental retardation
0.394 0.606 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.390 0.610 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.390 0.610 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.388 0.611 0.000
T36 Poisoning by systemic antibiotics
0.388 0.612 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.385 0.615 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.383 0.617 0.000
C45 Mesothelioma
0.383 0.617 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.383 0.617 0.000
F34 Persistent mood [affective] disorders
0.380 0.620 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.621 0.379
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.378 0.622 0.000
F30.9 Manic episode, unspecified
0.378 0.622 0.000
T50.4 Drugs affecting uric acid metabolism
0.378 0.622 0.000
F60.6 Anxious [avoidant] personality disorder
0.377 0.622 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.377 0.623 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.377 0.623 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.623 0.376
E63 Other nutritional deficiencies
0.000 0.623 0.376
E56 Other vitamin deficiencies
0.000 0.623 0.376
E50 Vitamin A deficiency
0.000 0.623 0.376
E60 Dietary zinc deficiency
0.000 0.623 0.376
E59 Dietary selenium deficiency
0.000 0.623 0.376
E54 Ascorbic acid deficiency
0.000 0.623 0.376
E52 Niacin deficiency [pellagra]
0.000 0.623 0.376
F48.0 Neurasthenia
0.376 0.624 0.000
F45.3 Somatoform autonomic dysfunction
0.376 0.624 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.375 0.625 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.375 0.625 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.374 0.626 0.000
F33.9 Recurrent depressive disorder, unspecified
0.374 0.626 0.000
F68 Other disorders of adult personality and behaviour
0.372 0.627 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.372 0.627 0.000
F65 Disorders of sexual preference
0.372 0.627 0.000
F63 Habit and impulse disorders
0.372 0.627 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.372 0.627 0.000
F61 Mixed and other personality disorders
0.372 0.627 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.372 0.627 0.000
C02.1 Border of tongue
0.372 0.628 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.372 0.628 0.000
M14 Arthropathies in other diseases classified elsewhere
0.371 0.628 0.000
C44.6 Skin of upper limb, including shoulder
0.370 0.630 0.000
F60.4 Histrionic personality disorder
0.369 0.631 0.000
F60.2 Dissocial personality disorder
0.369 0.631 0.000
F60.1 Schizoid personality disorder
0.369 0.631 0.000
F60.0 Paranoid personality disorder
0.369 0.631 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.369 0.631 0.000
F30.0 Hypomania
0.368 0.632 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.367 0.633 0.000
M70.4 Prepatellar bursitis
0.363 0.637 0.000
C95.0 Acute leukaemia of unspecified cell type
0.362 0.638 0.000
M85.6 Other cyst of bone
0.362 0.638 0.000
E51 Thiamine deficiency
0.000 0.641 0.359
C90.1 Plasma cell leukaemia
0.358 0.642 0.000
F20 Schizophrenia
0.357 0.643 0.000
I21.4 Acute subendocardial myocardial infarction
0.357 0.643 0.000
M84 Disorders of continuity of bone
0.356 0.644 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.356 0.644 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.356 0.644 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.356 0.644 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.356 0.644 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.356 0.644 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.356 0.644 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.356 0.644 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.356 0.644 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.356 0.644 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.356 0.644 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.356 0.644 0.000
M07.18 Arthritis mutilans (Other)
0.356 0.644 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.356 0.644 0.000
M07.16 Arthritis mutilans (Lower leg)
0.356 0.644 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.356 0.644 0.000
M07.14 Arthritis mutilans (Hand)
0.356 0.644 0.000
M07.13 Arthritis mutilans (Forearm)
0.356 0.644 0.000
M07.12 Arthritis mutilans (Upper arm)
0.356 0.644 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.356 0.644 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.356 0.644 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.356 0.644 0.000
M07.28 Psoriatic spondylitis (Other)
0.356 0.644 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.356 0.644 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.356 0.644 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.356 0.644 0.000
M07.24 Psoriatic spondylitis (Hand)
0.356 0.644 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.356 0.644 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.356 0.644 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.356 0.644 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.356 0.644 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.356 0.644 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.356 0.644 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.356 0.644 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.356 0.644 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.356 0.644 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.356 0.644 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.356 0.644 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.356 0.644 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.356 0.644 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.356 0.644 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.356 0.644 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.356 0.644 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.356 0.644 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.356 0.644 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.356 0.644 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.356 0.644 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.356 0.644 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.356 0.644 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.356 0.644 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.356 0.644 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.356 0.644 0.000
M07.68 Other enteropathic arthropathies (Other)
0.356 0.644 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.356 0.644 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.356 0.644 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.356 0.644 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.356 0.644 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.356 0.644 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.356 0.644 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.356 0.644 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.356 0.644 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.355 0.645 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.355 0.645 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.355 0.645 0.000
F44.5 Dissociative convulsions
0.354 0.646 0.000
M67.0 Short Achilles tendon (acquired)
0.353 0.647 0.000
C90.3 Solitary plasmacytoma
0.352 0.648 0.000
C95.7 Other leukaemia of unspecified cell type
0.352 0.648 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.352 0.648 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.352 0.648 0.000
M77 Other enthesopathies
0.351 0.649 0.000
M62.0 Diastasis of muscle
0.350 0.650 0.000
F43.0 Acute stress reaction
0.350 0.650 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.349 0.651 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.349 0.651 0.000
M76 Enthesopathies of lower limb, excluding foot
0.348 0.652 0.000
M67.1 Other contracture of tendon (sheath)
0.347 0.653 0.000
F38 Other mood [affective] disorders
0.347 0.653 0.000
E67 Other hyperalimentation
0.000 0.654 0.346
E68 Sequelae of hyperalimentation
0.000 0.654 0.346
M09 Juvenile arthritis in diseases classified elsewhere
0.346 0.654 0.000
M08 Juvenile arthritis
0.346 0.654 0.000
I05-I09 Chronic rheumatic heart diseases
0.346 0.654 0.000
M62.9 Disorder of muscle, unspecified
0.345 0.655 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.345 0.655 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.345 0.655 0.000
L57.5 Actinic granuloma
0.344 0.656 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.344 0.656 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.344 0.656 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.344 0.656 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.344 0.656 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.344 0.656 0.000
T44.0 Anticholinesterase agents
0.344 0.656 0.000
I27 Other pulmonary heart diseases
0.344 0.656 0.000
M71 Other bursopathies
0.343 0.657 0.000
C45.0 Mesothelioma of pleura
0.343 0.657 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.342 0.658 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.342 0.658 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.342 0.658 0.000
T47.7 Emetics
0.342 0.658 0.000
T47.6 Antidiarrhoeal drugs
0.342 0.658 0.000
T47.5 Digestants
0.342 0.658 0.000
T47.4 Other laxatives
0.342 0.658 0.000
T47.3 Saline and osmotic laxatives
0.342 0.658 0.000
T47.2 Stimulant laxatives
0.342 0.658 0.000
T47.0 Histamine H(2)-receptor antagonists
0.342 0.658 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.342 0.658 0.000
C88 Malignant immunoproliferative diseases
0.340 0.660 0.000
E13.8 With unspecified complications
0.000 0.660 0.340
E13.7 With multiple complications
0.000 0.660 0.340
E13.6 With other specified complications
0.000 0.660 0.340
E13.5 With peripheral circulatory complications
0.000 0.660 0.340
E13.4 With neurological complications
0.000 0.660 0.340
E13.2 With renal complications
0.000 0.660 0.340
E13.1 With ketoacidosis
0.000 0.660 0.340
E13.0 With coma
0.000 0.660 0.340
F33.1 Recurrent depressive disorder, current episode moderate
0.339 0.661 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.339 0.661 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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