TreeWAS – Variant ID: rs2844482

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
H65-H75 Diseases of middle ear and mastoid	1.000	0.000	0.000
Chapter VIII Diseases of the ear and mastoid process	1.000	0.000	0.000
E11.9 Without complications	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001	0.000
E70-E90 Metabolic disorders	0.999	0.001	0.000
E10.9 Without complications	0.996	0.004	0.000
H71 Cholesteatoma of middle ear	0.995	0.005	0.000
S00-S09 Injuries to the head	0.992	0.008	0.000
S02 Fracture of skull and facial bones	0.989	0.011	0.000
K50.9 Crohn's disease, unspecified	0.988	0.012	0.000
K50 Crohn's disease [regional enteritis]	0.987	0.013	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.986	0.014	0.000
Chapter XX External causes of morbidity and mortality	0.986	0.014	0.000
T66-T78 Other and unspecified effects of external causes	0.985	0.015	0.000
E78.0 Pure hypercholesterolaemia	0.985	0.015	0.000
Chapter V Mental and behavioural disorders	0.984	0.016	0.000
H73 Other disorders of tympanic membrane	0.981	0.019	0.000
K50-K52 Noninfective enteritis and colitis	0.979	0.021	0.000
Chapter XI Diseases of the digestive system	0.976	0.024	0.000
S02.4 Fracture of malar and maxillary bones	0.974	0.026	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.972	0.028	0.000
R31 Unspecified haematuria	0.971	0.029	0.000
E10.3 With ophthalmic complications	0.968	0.032	0.000
K90-K93 Other diseases of the digestive system	0.964	0.034	0.001
H73.8 Other specified disorders of tympanic membrane	0.965	0.035	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.963	0.037	0.000
T78 Adverse effects, not elsewhere classified	0.963	0.037	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.962	0.038	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.961	0.039	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.961	0.039	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.959	0.041	0.000
E85 Amyloidosis	0.958	0.042	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.957	0.043	0.000
E11.3 With ophthalmic complications	0.954	0.046	0.000
E20-E35 Disorders of other endocrine glands	0.949	0.051	0.000
S06 Intracranial injury	0.946	0.054	0.000
W00-W19 Falls	0.944	0.056	0.000
E10.4 With neurological complications	0.944	0.056	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.942	0.058	0.000
H60-H62 Diseases of external ear	0.941	0.059	0.000
H74 Other disorders of middle ear and mastoid	0.939	0.061	0.000
F01 Vascular dementia	0.937	0.063	0.000
E14 Unspecified diabetes mellitus	0.936	0.064	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.932	0.068	0.000
K50.1 Crohn's disease of large intestine	0.931	0.069	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.930	0.070	0.000
H66 Suppurative and unspecified otitis media	0.927	0.073	0.000
E10.5 With peripheral circulatory complications	0.924	0.076	0.000
Y57 Other and unspecified drugs and medicaments	0.923	0.077	0.000
S40-S49 Injuries to the shoulder and upper arm	0.913	0.087	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.909	0.091	0.000
E10.1 With ketoacidosis	0.909	0.091	0.000
F01.9 Vascular dementia, unspecified	0.906	0.094	0.000
H66.3 Other chronic suppurative otitis media	0.903	0.097	0.000
W20-W49 Exposure to inanimate mechanical forces	0.901	0.099	0.000
E21.3 Hyperparathyroidism, unspecified	0.901	0.099	0.000
T78.3 Angioneurotic oedema	0.900	0.100	0.000
S02.1 Fracture of base of skull	0.890	0.110	0.000
F06.7 Mild cognitive disorder	0.890	0.110	0.000
H90-H95 Other disorders of ear	0.889	0.111	0.000
E11.0 With coma	0.889	0.111	0.000
S06.5 Traumatic subdural haemorrhage	0.888	0.112	0.000
H61 Other disorders of external ear	0.883	0.117	0.000
H74.4 Polyp of middle ear	0.877	0.123	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.875	0.125	0.000
E89.3 Postprocedural hypopituitarism	0.872	0.128	0.000
S06.2 Diffuse brain injury	0.872	0.128	0.000
E85.9 Amyloidosis, unspecified	0.871	0.129	0.000
Y40 Systemic antibiotics	0.868	0.132	0.000
Q80-Q89 Other congenital malformations	0.864	0.136	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.864	0.136	0.000
Y57.9 Drug or medicament, unspecified	0.864	0.136	0.000
Q25 Congenital malformations of great arteries	0.863	0.137	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.862	0.138	0.000
W15 Fall from cliff	0.862	0.138	0.000
E11.4 With neurological complications	0.860	0.140	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.859	0.141	0.000
E50-E64 Other nutritional deficiencies	0.859	0.141	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.859	0.141	0.000
F80-F89 Disorders of psychological development	0.857	0.143	0.000
E65-E68 Obesity and other hyperalimentation	0.856	0.144	0.000
H92 Otalgia and effusion of ear	0.852	0.148	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.851	0.149	0.000
V10-V19 Pedal cyclist injured in transport accident	0.851	0.149	0.000
S02.0 Fracture of vault of skull	0.850	0.150	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.850	0.150	0.000
Q23 Congenital malformations of aortic and mitral valves	0.849	0.151	0.000
K50.8 Other Crohn's disease	0.849	0.151	0.000
W05 Fall involving wheelchair	0.847	0.153	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.846	0.154	0.000
W50-W64 Exposure to animate mechanical forces	0.845	0.155	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.843	0.157	0.000
E10.8 With unspecified complications	0.843	0.157	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.843	0.157	0.000
T00-T07 Injuries involving multiple body regions	0.842	0.158	0.000
E89.1 Postprocedural hypoinsulinaemia	0.840	0.160	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.832	0.168	0.000
S42 Fracture of shoulder and upper arm	0.832	0.168	0.000
L05 Pilonidal cyst	0.831	0.169	0.000
E11.5 With peripheral circulatory complications	0.823	0.177	0.000
Q24 Other congenital malformations of heart	0.821	0.179	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.820	0.180	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.820	0.180	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.819	0.181	0.000
S02.10 Fracture of base of skull (closed)	0.819	0.181	0.000
E85.3 Secondary systemic amyloidosis	0.817	0.183	0.000
H61.0 Perichondritis of external ear	0.817	0.183	0.000
E65 Localised adiposity	0.817	0.183	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.816	0.184	0.000
E79 Disorders of purine and pyrimidine metabolism	0.816	0.184	0.000
H92.1 Otorrhoea	0.815	0.185	0.000
E11.6 With other specified complications	0.812	0.188	0.000
L05.0 Pilonidal cyst with abscess	0.811	0.189	0.000
S40 Superficial injury of shoulder and upper arm	0.810	0.190	0.000
T70 Effects of air pressure and water pressure	0.808	0.192	0.000
T78.9 Adverse effect, unspecified	0.807	0.193	0.000
W08 Fall involving other furniture	0.806	0.194	0.000
E20 Hypoparathyroidism	0.804	0.196	0.000
H65 Nonsuppurative otitis media	0.798	0.202	0.000
E26 Hyperaldosteronism	0.793	0.207	0.000
E89.2 Postprocedural hypoparathyroidism	0.791	0.209	0.000
Y00-Y09 Assault	0.790	0.210	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.789	0.211	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.789	0.211	0.000
Y52 Agents primarily affecting the cardiovascular system	0.789	0.211	0.000
T71 Asphyxiation	0.789	0.211	0.000
S70-S79 Injuries to the hip and thigh	0.786	0.214	0.000
E14.8 With unspecified complications	0.786	0.214	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.786	0.214	0.000
W13 Fall from, out of or through building or structure	0.785	0.215	0.000
E85.4 Organ-limited amyloidosis	0.783	0.217	0.000
K52 Other non-infective gastro-enteritis and colitis	0.781	0.219	0.000
T75 Effects of other external causes	0.779	0.220	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.779	0.221	0.000
W29 Contact with other powered hand tools and household machinery	0.779	0.221	0.000
S02.8 Fractures of other skull and facial bones	0.776	0.224	0.000
F60-F69 Disorders of adult personality and behaviour	0.776	0.224	0.000
W15.9 Unspecified place	0.776	0.224	0.000
K90 Intestinal malabsorption	0.409	0.224	0.367
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.775	0.225	0.000
Y10-Y34 Event of undetermined intent	0.775	0.225	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.774	0.226	0.000
Y40.0 Penicillins	0.773	0.227	0.000
S02.6 Fracture of mandible	0.773	0.227	0.000
Q85 Phakomatoses, not elsewhere classified	0.772	0.228	0.000
K50.0 Crohn's disease of small intestine	0.772	0.228	0.000
K52.1 Toxic gastro-enteritis and colitis	0.772	0.228	0.000
E10.0 With coma	0.771	0.229	0.000
F84 Pervasive developmental disorders	0.770	0.230	0.000
Y59 Other and unspecified vaccines and biological substances	0.770	0.230	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.769	0.231	0.000
H72 Perforation of tympanic membrane	0.768	0.232	0.000
K08 Other disorders of teeth and supporting structures	0.768	0.232	0.000
V01-V09 Pedestrian injured in transport accident	0.768	0.232	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.766	0.234	0.000
E14.6 With other specified complications	0.766	0.234	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.765	0.235	0.000
Y46.2 Hydantoin derivatives	0.765	0.235	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.765	0.235	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.765	0.235	0.000
E61 Deficiency of other nutrient elements	0.763	0.237	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.762	0.238	0.000
Y57.8 Other drugs and medicaments	0.761	0.239	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.760	0.240	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.759	0.241	0.000
X00-X09 Exposure to smoke, fire and flames	0.758	0.242	0.000
E21.4 Other specified disorders of parathyroid gland	0.758	0.242	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.755	0.245	0.000
W75-W84 Other accidental threats to breathing	0.754	0.246	0.000
L03 Cellulitis	0.754	0.246	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.753	0.247	0.000
M86-M90 Other osteopathies	0.752	0.248	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.752	0.248	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.751	0.249	0.000
S02.00 Fracture of vault of skull (closed)	0.751	0.249	0.000
W05.9 Unspecified place	0.749	0.251	0.000
X50-X57 Overexertion, travel and privation	0.748	0.252	0.000
H61.2 Impacted cerumen	0.748	0.252	0.000
S32 Fracture of lumbar spine and pelvis	0.747	0.253	0.000
S42.0 Fracture of clavicle	0.746	0.254	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.746	0.254	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.746	0.254	0.000
Q23.1 Congenital insufficiency of aortic valve	0.745	0.255	0.000
H60 Otitis externa	0.745	0.255	0.000
Y58 Bacterial vaccines	0.741	0.259	0.000
M05-M14 Inflammatory polyarthropathies	0.741	0.259	0.000
Q25.1 Coarctation of aorta	0.741	0.259	0.000
Y57.6 Other diagnostic agents	0.741	0.259	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.740	0.259	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.740	0.260	0.000
E14.9 Without complications	0.740	0.260	0.000
W10 Fall on and from stairs and steps	0.740	0.260	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.739	0.261	0.000
E10.6 With other specified complications	0.739	0.261	0.000
Q21 Congenital malformations of cardiac septa	0.739	0.261	0.000
L03.3 Cellulitis of trunk	0.738	0.262	0.000
K91.1 Postgastric surgery syndromes	0.738	0.262	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.738	0.262	0.000
F99-F99 Unspecified mental disorder	0.737	0.263	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.736	0.264	0.000
S02.5 Fracture of tooth	0.734	0.266	0.000
S06.9 Intracranial injury, unspecified	0.734	0.266	0.000
E84 Cystic fibrosis	0.732	0.268	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.730	0.269	0.000
L05.9 Pilonidal cyst without abscess	0.729	0.271	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.728	0.272	0.000
H70 Mastoiditis and related conditions	0.727	0.273	0.000
W26 Contact with knife, sword or dagger	0.726	0.274	0.000
F01.1 Multi-infarct dementia	0.726	0.274	0.000
S60-S69 Injuries to the wrist and hand	0.725	0.275	0.000
E14.5 With peripheral circulatory complications	0.724	0.276	0.000
F70-F79 Mental retardation	0.724	0.276	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.723	0.277	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.722	0.278	0.000
V98-V99 Other and unspecified transport accidents	0.722	0.278	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.722	0.278	0.000
Q25.4 Other congenital malformations of aorta	0.722	0.278	0.000
W55 Bitten or struck by other mammals	0.722	0.278	0.000
S42.4 Fracture of lower end of humerus	0.721	0.279	0.000
T78.8 Other adverse effects, not elsewhere classified	0.721	0.279	0.000
E21.2 Other hyperparathyroidism	0.721	0.279	0.000
E78.6 Lipoprotein deficiency	0.719	0.281	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.718	0.282	0.000
K05 Gingivitis and periodontal diseases	0.717	0.283	0.000
E10.7 With multiple complications	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E11.7 With multiple complications	0.717	0.283	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.717	0.283	0.000
H68 Eustachian salpingitis and obstruction	0.717	0.283	0.000
H67 Otitis media in diseases classified elsewhere	0.717	0.283	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.717	0.283	0.000
T33-T35 Frostbite	0.716	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.283	0.000
F02 Dementia in other diseases classified elsewhere	0.716	0.284	0.000
H74.1 Adhesive middle ear disease	0.716	0.284	0.000
E77 Disorders of glycoprotein metabolism	0.716	0.284	0.000
E76 Disorders of glycosaminoglycan metabolism	0.716	0.284	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.716	0.284	0.000
E72 Other disorders of amino-acid metabolism	0.716	0.284	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.716	0.284	0.000
E70 Disorders of aromatic amino-acid metabolism	0.716	0.284	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.716	0.284	0.000
Q24.8 Other specified congenital malformations of heart	0.715	0.285	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.715	0.285	0.000
E89.4 Postprocedural ovarian failure	0.714	0.286	0.000
Y40.9 Systemic antibiotic, unspecified	0.714	0.286	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.712	0.288	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.711	0.289	0.000
E74 Other disorders of carbohydrate metabolism	0.711	0.289	0.000
S70 Superficial injury of hip and thigh	0.711	0.289	0.000
S08 Traumatic amputation of part of head	0.711	0.289	0.000
S07 Crushing injury of head	0.711	0.289	0.000
S04 Injury of cranial nerves	0.711	0.289	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.710	0.290	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.710	0.290	0.000
S02.2 Fracture of nasal bones	0.709	0.291	0.000
F84.5 Asperger's syndrome	0.708	0.292	0.000
E88 Other metabolic disorders	0.708	0.292	0.000
E78.3 Hyperchylomicronaemia	0.707	0.293	0.000
Y35-Y36 Legal intervention and operations of war	0.707	0.293	0.000
X85-X99 Assault	0.707	0.293	0.000
X30-X39 Exposure to forces of nature	0.707	0.293	0.000
W65-W74 Accidental drowning and submersion	0.707	0.293	0.000
V95-V97 Air and space transport accidents	0.707	0.293	0.000
V90-V94 Water transport accidents	0.707	0.293	0.000
V70-V79 Bus occupant injured in transport accident	0.707	0.293	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293	0.000
T88.4 Failed or difficult intubation	0.706	0.294	0.000
T74 Maltreatment syndromes	0.706	0.294	0.000
T73 Effects of other deprivation	0.706	0.294	0.000
T69 Other effects of reduced temperature	0.706	0.294	0.000
T67 Effects of heat and light	0.706	0.294	0.000
T66 Unspecified effects of radiation	0.706	0.294	0.000
E29 Testicular dysfunction	0.706	0.294	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.706	0.294	0.000
W14 Fall from tree	0.705	0.295	0.000
E14.4 With neurological complications	0.704	0.296	0.000
H66.4 Suppurative otitis media, unspecified	0.704	0.296	0.000
H73.1 Chronic myringitis	0.704	0.296	0.000
H73.0 Acute myringitis	0.704	0.296	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.703	0.297	0.000
W03.9 Unspecified place	0.703	0.297	0.000
S40.0 Contusion of shoulder and upper arm	0.702	0.298	0.000
E51 Thiamine deficiency	0.702	0.298	0.000
E25 Adrenogenital disorders	0.701	0.299	0.000
F43 Reaction to severe stress, and adjustment disorders	0.701	0.299	0.000
E61.1 Iron deficiency	0.700	0.300	0.000
M60-M63 Disorders of muscles	0.700	0.300	0.000
X20-X29 Contact with venomous animals and plants	0.700	0.300	0.000
S02.3 Fracture of orbital floor	0.700	0.300	0.000
E20.9 Hypoparathyroidism, unspecified	0.700	0.300	0.000
T01 Open wounds involving multiple body regions	0.699	0.301	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.699	0.301	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.699	0.301	0.000
H65.2 Chronic serous otitis media	0.699	0.301	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.698	0.302	0.000
F09 Unspecified organic or symptomatic mental disorder	0.697	0.303	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.697	0.303	0.000
M88 Paget's disease of bone [osteitis deformans]	0.697	0.303	0.000
Z93.2 Ileostomy status	0.696	0.304	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.695	0.305	0.000
Q23.0 Congenital stenosis of aortic valve	0.695	0.305	0.000
E14.3 With ophthalmic complications	0.694	0.306	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.694	0.306	0.000
T20 Burn and corrosion of head and neck	0.694	0.306	0.000
W08.0 Home	0.693	0.307	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.693	0.307	0.000
W15.8 Other specified place	0.693	0.307	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.691	0.308	0.001
E80 Disorders of porphyrin and bilirubin metabolism	0.692	0.308	0.000
E10.2 With renal complications	0.692	0.308	0.000
W34 Discharge from other and unspecified firearms	0.692	0.308	0.000
W29.9 Unspecified place	0.689	0.311	0.000
Q35-Q37 Cleft lip and cleft palate	0.689	0.311	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.689	0.311	0.000
Y40.4 Tetracyclines	0.689	0.311	0.000
S05 Injury of eye and orbit	0.689	0.311	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.689	0.311	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.689	0.311	0.000
F00 Dementia in Alzheimer's disease	0.689	0.311	0.000
E85.8 Other amyloidosis	0.687	0.313	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.687	0.313	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.687	0.313	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.687	0.313	0.000
T79-T79 Certain early complications of trauma	0.686	0.314	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.686	0.314	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.686	0.314	0.000
E89.5 Postprocedural testicular hypofunction	0.686	0.314	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.686	0.314	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.686	0.314	0.000
E73 Lactose intolerance	0.685	0.315	0.000
S42.00 Fracture of clavicle (closed)	0.685	0.315	0.000
W28 Contact with powered lawn mower	0.685	0.315	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.684	0.316	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.684	0.316	0.000
W20 Struck by thrown, projected or falling object	0.683	0.317	0.000
M05 Seropositive rheumatoid arthritis	0.683	0.317	0.000
Y43 Primarily systemic agents	0.683	0.317	0.000
L04 Acute lymphadenitis	0.682	0.318	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.681	0.319	0.000
E32 Diseases of thymus	0.681	0.319	0.000
E31 Polyglandular dysfunction	0.681	0.319	0.000
E30 Disorders of puberty, not elsewhere classified	0.681	0.319	0.000
T70.3 Caisson disease [decompression sickness]	0.680	0.320	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.680	0.320	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.680	0.320	0.000
Q82 Other congenital malformations of skin	0.679	0.321	0.000
E78.2 Mixed hyperlipidaemia	0.678	0.322	0.000
S06.7 Intracranial injury with prolonged coma	0.678	0.322	0.000
S06.1 Traumatic cerebral oedema	0.678	0.322	0.000
M11 Other crystal arthropathies	0.678	0.322	0.000
W05.0 Home	0.677	0.323	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.677	0.323	0.000
W12 Fall on and from scaffolding	0.677	0.323	0.000
W09 Fall involving playground equipment	0.677	0.323	0.000
W04 Fall while being carried or supported by other persons	0.677	0.323	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.677	0.323	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.676	0.324	0.000
Q26 Congenital malformations of great veins	0.675	0.324	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.675	0.324	0.000
Y46.4 Iminostilbenes	0.675	0.325	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.674	0.325	0.000
S42.1 Fracture of scapula	0.674	0.326	0.000
H92.0 Otalgia	0.674	0.326	0.000
K12 Stomatitis and related lesions	0.673	0.327	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.673	0.327	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.672	0.328	0.000
F01.8 Other vascular dementia	0.672	0.328	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.672	0.328	0.000
F01.2 Subcortical vascular dementia	0.672	0.328	0.000
F01.0 Vascular dementia of acute onset	0.672	0.328	0.000
W45 Foreign body or object entering through skin	0.671	0.329	0.000
E14.7 With multiple complications	0.671	0.329	0.000
E14.2 Withrenal complications	0.671	0.329	0.000
E14.1 With ketoacidosis	0.671	0.329	0.000
E14.0 With coma	0.671	0.329	0.000
T25 Burn and corrosion of ankle and foot	0.671	0.329	0.000
W13.9 Unspecified place	0.671	0.329	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.670	0.330	0.000
Q25.6 Stenosis of pulmonary artery	0.668	0.331	0.000
S32.4 Fracture of acetabulum	0.668	0.332	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.668	0.332	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.668	0.332	0.000
F06.5 Organic dissociative disorder	0.668	0.332	0.000
F06.4 Organic anxiety disorder	0.668	0.332	0.000
F06.3 Organic mood [affective] disorders	0.668	0.332	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.668	0.332	0.000
F06.1 Organic catatonic disorder	0.668	0.332	0.000
F06.0 Organic hallucinosis	0.668	0.332	0.000
F43.0 Acute stress reaction	0.667	0.333	0.000
Y04 Assault by bodily force	0.667	0.333	0.000
T23 Burn and corrosion of wrist and hand	0.667	0.333	0.000
H61.1 Non-infective disorders of pinna	0.667	0.333	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.667	0.333	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.667	0.333	0.000
H65.3 Chronic mucoid otitis media	0.667	0.333	0.000
W00 Fall on same level involving ice and snow	0.666	0.334	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.666	0.334	0.000
Y44 Agents primarily affecting blood constituents	0.666	0.334	0.000
H61.9 Disorder of external ear, unspecified	0.666	0.334	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.665	0.335	0.000
H66.0 Acute suppurative otitis media	0.664	0.335	0.000
F03 Unspecified dementia	0.664	0.336	0.000
Y40.5 Aminoglycosides	0.663	0.337	0.000
W18 Other fall on same level	0.663	0.337	0.000
Y57.7 Vitamins, not elsewhere classified	0.662	0.338	0.000
Y57.4 Pharmaceutical excipients	0.662	0.338	0.000
Y57.3 Alcohol deterrents	0.662	0.338	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.662	0.338	0.000
Y57.1 Lipotropic drugs	0.662	0.338	0.000
Y57.0 Appetite depressants [anorectics]	0.662	0.338	0.000
S43.0 Dislocation of shoulder joint	0.661	0.339	0.000
F60 Specific personality disorders	0.660	0.340	0.000
Y46.7 Anti-Parkinsonism drugs	0.660	0.340	0.000
Q83 Congenital malformations of breast	0.660	0.340	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.660	0.340	0.000
T88.2 Shock due to anaesthesia	0.659	0.341	0.000
K91.5 Postcholecystectomy syndrome	0.659	0.341	0.000
M86 Osteomyelitis	0.658	0.342	0.000
E28 Ovarian dysfunction	0.658	0.342	0.000
E11.2 With renal complications	0.656	0.344	0.000
S48 Traumatic amputation of shoulder and upper arm	0.654	0.345	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.654	0.345	0.000
S44 Injury of nerves at shoulder and upper arm level	0.654	0.345	0.000
S47 Crushing injury of shoulder and upper arm	0.654	0.345	0.000
S02.7 Multiple fractures involving skull and facial bones	0.654	0.346	0.000
S09 Other and unspecified injuries of head	0.654	0.346	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.653	0.347	0.000
W11 Fall on and from ladder	0.653	0.347	0.000
Q50-Q56 Congenital malformations of genital organs	0.652	0.348	0.000
Y57.5 X-ray contrast media	0.652	0.348	0.000
T87 Complications peculiar to reattachment and amputation	0.652	0.348	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.651	0.349	0.000
S06.3 Focal brain injury	0.651	0.349	0.000
L57.0 Actinic keratosis	0.651	0.349	0.000
W49.0 Home	0.651	0.349	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.651	0.349	0.000
K10 Other diseases of jaws	0.650	0.350	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.650	0.350	0.000
M62 Other disorders of muscle	0.649	0.351	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.649	0.351	0.000
F80 Specific developmental disorders of speech and language	0.649	0.351	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.648	0.352	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.647	0.353	0.000
W46 Contact with hypodermic needle	0.646	0.354	0.000
W43 Exposure to vibration	0.646	0.354	0.000
W42 Exposure to noise	0.646	0.354	0.000
W41 Exposure to high-pressure jet	0.646	0.354	0.000
W40 Explosion of other materials	0.646	0.354	0.000
W39 Discharge of firework	0.646	0.354	0.000
W38 Explosion and rupture of other specified pressurised devices	0.646	0.354	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.646	0.354	0.000
W36 Explosion and rupture of gas cylinder	0.646	0.354	0.000
W35 Explosion and rupture of boiler	0.646	0.354	0.000
W33 Rifle, shotgun and larger firearm discharge	0.646	0.354	0.000
W32 Handgun discharge	0.646	0.354	0.000
W31 Contact with other and unspecified machinery	0.646	0.354	0.000
W30 Contact with agricultural machinery	0.646	0.354	0.000
W27 Contact with nonpowered hand tool	0.646	0.354	0.000
E23 Hypofunction and other disorders of pituitary gland	0.645	0.354	0.000
E34 Other endocrine disorders	0.645	0.355	0.000
H72.8 Other perforations of tympanic membrane	0.645	0.355	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.645	0.355	0.000
M88.9 Paget's disease of bone, unspecified	0.645	0.355	0.000
Q00-Q07 Congenital malformations of the nervous system	0.644	0.356	0.000
W03.0 Home	0.643	0.357	0.000
W07 Fall involving chair	0.642	0.358	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.641	0.359	0.000
K14 Diseases of tongue	0.641	0.359	0.000
W17 Other fall from one level to another	0.640	0.359	0.000
F51 Nonorganic sleep disorders	0.639	0.361	0.000
S37 Injury of urinary and pelvic organs	0.639	0.361	0.000
K03 Other diseases of hard tissues of teeth	0.639	0.361	0.000
M90 Osteopathies in diseases classified elsewhere	0.639	0.361	0.000
T00 Superficial injuries involving multiple body regions	0.638	0.361	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.638	0.361	0.000
S02.11 Fracture of base of skull (open)	0.638	0.362	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.638	0.362	0.000
S06.0 Concussion	0.638	0.362	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.638	0.362	0.000
M00-M03 Infectious arthropathies	0.637	0.363	0.000
M70-M79 Other soft tissue disorders	0.637	0.363	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.637	0.363	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.636	0.363	0.000
E26.0 Primary hyperaldosteronism	0.636	0.364	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.635	0.365	0.000
S43.1 Dislocation of acromioclavicular joint	0.635	0.365	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.635	0.365	0.000
S42.2 Fracture of upper end of humerus	0.635	0.365	0.000
E78.1 Pure hyperglyceridaemia	0.635	0.365	0.000
Y59.3 Immunoglobulin	0.634	0.366	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations