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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs74736071
log Bayes Factor = 21.8989
Chromosome 3   position 136,604,687  (GRCh37) Explore rs74736071 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.000 0.000 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.999 0.001 0.000
Y83.8 Other surgical procedures
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.997 0.003 0.000
R30-R39 Symptoms and signs involving the urinary system
0.993 0.007 0.000
T81 Complications of procedures, not elsewhere classified
0.991 0.009 0.000
N20-N23 Urolithiasis
0.991 0.009 0.000
R39 Other symptoms and signs involving the urinary system
0.986 0.014 0.000
N20 Calculus of kidney and ureter
0.986 0.014 0.000
M20-M25 Other joint disorders
0.984 0.016 0.000
Chapter VII Diseases of the eye and adnexa
0.980 0.020 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.979 0.021 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
Chapter VIII Diseases of the ear and mastoid process
0.971 0.029 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.965 0.035 0.000
S80-S89 Injuries to the knee and lower leg
0.960 0.040 0.000
M06 Other rheumatoid arthritis
0.957 0.043 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.957 0.043 0.000
S60-S69 Injuries to the wrist and hand
0.956 0.044 0.000
N20.0 Calculus of kidney
0.955 0.045 0.000
M23 Internal derangement of knee
0.949 0.051 0.000
N20.1 Calculus of ureter
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.941 0.059 0.000
N10-N16 Renal tubulo-interstitial diseases
0.933 0.067 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.932 0.068 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.932 0.068 0.000
Chapter XI Diseases of the digestive system
0.932 0.068 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.929 0.071 0.000
S00-S09 Injuries to the head
0.928 0.072 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.928 0.072 0.000
G90-G99 Other disorders of the nervous system
0.926 0.074 0.000
M10 Gout
0.918 0.082 0.000
H90-H95 Other disorders of ear
0.915 0.085 0.000
M06.9 Rheumatoid arthritis, unspecified
0.913 0.087 0.000
M13 Other arthritis
0.911 0.089 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.905 0.095 0.000
S61 Open wound of wrist and hand
0.905 0.095 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.905 0.095 0.000
R94 Abnormal results of function studies
0.903 0.096 0.000
M80-M85 Disorders of bone density and structure
0.901 0.099 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.900 0.100 0.000
G93 Other disorders of brain
0.897 0.103 0.000
Chapter X Diseases of the respiratory system
0.897 0.103 0.000
N13 Obstructive and reflux uropathy
0.894 0.106 0.000
M15-M19 Arthrosis
0.886 0.114 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.886 0.114 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.885 0.115 0.000
M70-M79 Other soft tissue disorders
0.883 0.117 0.000
S20-S29 Injuries to the thorax
0.880 0.120 0.000
R94.5 Abnormal results of liver function studies
0.880 0.120 0.000
R35 Polyuria
0.878 0.122 0.000
R33 Retention of urine
0.874 0.126 0.000
S80 Superficial injury of lower leg
0.869 0.131 0.000
H91 Other hearing loss
0.866 0.134 0.000
S81 Open wound of lower leg
0.866 0.134 0.000
M10.9 Gout, unspecified
0.861 0.139 0.000
M65-M68 Disorders of synovium and tendon
0.859 0.141 0.000
M25 Other joint disorders, not elsewhere classified
0.858 0.142 0.000
B95-B98 Bacterial, viral and other infectious agents
0.855 0.145 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.854 0.146 0.000
N17-N19 Renal failure
0.853 0.147 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.851 0.149 0.000
M13.9 Arthritis, unspecified
0.849 0.151 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.849 0.151 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.848 0.152 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.847 0.153 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.847 0.153 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.845 0.155 0.000
H65-H75 Diseases of middle ear and mastoid
0.843 0.157 0.000
L20-L30 Dermatitis and eczema
0.843 0.157 0.000
S61.0 Open wound of finger(s) without damage to nail
0.842 0.158 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.841 0.159 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.840 0.160 0.000
R04 Haemorrhage from respiratory passages
0.840 0.160 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.839 0.161 0.000
Y95 Nosocomial condition
0.837 0.163 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.837 0.163 0.000
K70-K77 Diseases of liver
0.832 0.168 0.000
O60-O75 Complications of labour and delivery
0.831 0.169 0.000
W20-W49 Exposure to inanimate mechanical forces
0.831 0.169 0.000
H91.9 Hearing loss, unspecified
0.831 0.169 0.000
K83 Other diseases of biliary tract
0.831 0.169 0.000
M81 Osteoporosis without pathological fracture
0.831 0.169 0.000
R30 Pain associated with micturition
0.829 0.171 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.827 0.173 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.827 0.173 0.000
J09-J18 Influenza and pneumonia
0.826 0.174 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.823 0.177 0.000
Y83.9 Surgical procedure, unspecified
0.823 0.177 0.000
M10.99 Gout, unspecified (Site unspecified)
0.821 0.179 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.820 0.180 0.000
M17 Gonarthrosis [arthrosis of knee]
0.818 0.182 0.000
S40-S49 Injuries to the shoulder and upper arm
0.818 0.182 0.000
H55-H59 Other disorders of eye and adnexa
0.816 0.184 0.000
S61.1 Open wound of finger(s) with damage to nail
0.815 0.185 0.000
Chapter V Mental and behavioural disorders
0.814 0.186 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.811 0.189 0.000
H53-H54 Visual disturbances and blindness
0.811 0.189 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.810 0.190 0.000
Chapter XXI Factors influencing health status and contact with health services
0.809 0.191 0.000
K40-K46 Hernia
0.808 0.192 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.807 0.193 0.000
R06 Abnormalities of breathing
0.804 0.196 0.000
L50-L54 Urticaria and erythema
0.803 0.197 0.000
M17.9 Gonarthrosis, unspecified
0.801 0.199 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.801 0.199 0.000
M40-M43 Deforming dorsopathies
0.799 0.201 0.000
R00 Abnormalities of heart beat
0.797 0.203 0.000
N17 Acute renal failure
0.794 0.206 0.000
M50-M54 Other dorsopathies
0.794 0.206 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.792 0.208 0.000
Y83.0 Surgical operation with transplant of whole organ
0.792 0.208 0.000
M05 Seropositive rheumatoid arthritis
0.791 0.209 0.000
M19 Other arthrosis
0.789 0.211 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.789 0.211 0.000
M65 Synovitis and tenosynovitis
0.787 0.213 0.000
R05 Cough
0.787 0.213 0.000
M91-M94 Chondropathies
0.787 0.213 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.786 0.214 0.000
R39.1 Other difficulties with micturition
0.786 0.214 0.000
M24 Other specific joint derangements
0.786 0.214 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.786 0.214 0.000
M06.4 Inflammatory polyarthropathy
0.784 0.216 0.000
S02 Fracture of skull and facial bones
0.783 0.217 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.781 0.219 0.000
M81.9 Osteoporosis, unspecified
0.781 0.219 0.000
S60 Superficial injury of wrist and hand
0.780 0.220 0.000
M25.5 Pain in joint
0.780 0.220 0.000
H40-H42 Glaucoma
0.779 0.220 0.000
M21 Other acquired deformities of limbs
0.779 0.221 0.000
M86-M90 Other osteopathies
0.779 0.221 0.000
S80.9 Superficial injury of lower leg, unspecified
0.778 0.222 0.000
S90-S99 Injuries to the ankle and foot
0.778 0.222 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.777 0.223 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.777 0.223 0.000
G93.6 Cerebral oedema
0.776 0.224 0.000
S00 Superficial injury of head
0.776 0.224 0.000
J18 Pneumonia, organism unspecified
0.774 0.226 0.000
K83.1 Obstruction of bile duct
0.774 0.226 0.000
K83.8 Other specified diseases of biliary tract
0.774 0.226 0.000
N25-N29 Other disorders of kidney and ureter
0.774 0.226 0.000
N60-N64 Disorders of breast
0.774 0.226 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.772 0.228 0.000
N20.2 Calculus of kidney with calculus of ureter
0.771 0.229 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.770 0.230 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.770 0.230 0.000
H04 Disorders of lachrymal system
0.769 0.231 0.000
R74 Abnormal serum enzyme levels
0.768 0.232 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.768 0.232 0.000
S81.8 Open wound of other parts of lower leg
0.767 0.233 0.000
T66-T78 Other and unspecified effects of external causes
0.765 0.235 0.000
S70-S79 Injuries to the hip and thigh
0.763 0.237 0.000
K76 Other diseases of liver
0.763 0.237 0.000
M79.8 Other specified soft tissue disorders
0.762 0.238 0.000
N23 Unspecified renal colic
0.762 0.238 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.762 0.238 0.000
D60-D64 Aplastic and other anaemias
0.759 0.241 0.000
G93.3 Postviral fatigue syndrome
0.757 0.243 0.000
N40-N51 Diseases of male genital organs
0.756 0.244 0.000
G93.9 Disorder of brain, unspecified
0.755 0.245 0.000
B25-B34 Other viral diseases
0.755 0.245 0.000
N13.8 Other obstructive and reflux uropathy
0.754 0.246 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.754 0.246 0.000
M31 Other necrotising vasculopathies
0.754 0.246 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.754 0.246 0.000
N17.9 Acute renal failure, unspecified
0.752 0.248 0.000
Y83.6 Removal of other organ (partial) (total)
0.752 0.248 0.000
H01 Other inflammation of eyelid
0.751 0.249 0.000
R02 Gangrene, not elsewhere classified
0.750 0.250 0.000
K50-K52 Noninfective enteritis and colitis
0.749 0.251 0.000
V10-V19 Pedal cyclist injured in transport accident
0.747 0.252 0.000
H43-H45 Disorders of vitreous body and globe
0.746 0.253 0.000
J18.1 Lobar pneumonia, unspecified
0.743 0.257 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.743 0.257 0.000
J84 Other interstitial pulmonary diseases
0.743 0.257 0.000
N00-N08 Glomerular diseases
0.743 0.257 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.742 0.258 0.000
Y84.6 Urinary catheterisation
0.741 0.259 0.000
K40 Inguinal hernia
0.738 0.262 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.738 0.262 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.738 0.262 0.000
M13.98 Arthritis, unspecified (Other)
0.738 0.262 0.000
M79.6 Pain in limb
0.738 0.262 0.000
Y44 Agents primarily affecting blood constituents
0.738 0.262 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.737 0.263 0.000
X60-X84 Intentional self-harm
0.736 0.264 0.000
R00.1 Bradycardia, unspecified
0.736 0.264 0.000
N64 Other disorders of breast
0.734 0.266 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.733 0.267 0.000
H60-H62 Diseases of external ear
0.731 0.269 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.731 0.269 0.000
S20 Superficial injury of thorax
0.730 0.270 0.000
E10-E14 Diabetes mellitus
0.729 0.271 0.000
A00-A09 Intestinal infectious diseases
0.728 0.272 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.728 0.272 0.000
T88.4 Failed or difficult intubation
0.728 0.272 0.000
E70-E90 Metabolic disorders
0.726 0.274 0.000
S82 Fracture of lower leg, including ankle
0.725 0.275 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.723 0.277 0.000
Y43 Primarily systemic agents
0.723 0.277 0.000
H80-H83 Diseases of inner ear
0.722 0.278 0.000
L27 Dermatitis due to substances taken internally
0.722 0.278 0.000
M25.8 Other specified joint disorders
0.721 0.279 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.720 0.280 0.000
G93.8 Other specified disorders of brain
0.718 0.282 0.000
S09 Other and unspecified injuries of head
0.718 0.282 0.000
R74.8 Abnormal levels of other serum enzymes
0.718 0.282 0.000
H92 Otalgia and effusion of ear
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Y83.5 Amputation of limb(s)
0.716 0.283 0.000
Y83.3 Surgical operation with formation of external stoma
0.716 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
M07 Psoriatic and enteropathic arthropathies
0.716 0.284 0.000
R04.2 Haemoptysis
0.716 0.284 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.285 0.000
M12 Other specific arthropathies
0.714 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.285 0.000
M08 Juvenile arthritis
0.714 0.285 0.000
H30-H36 Disorders of choroid and retina
0.714 0.286 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.713 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.712 0.287 0.000
R36 Urethral discharge
0.712 0.288 0.000
R34 Anuria and oliguria
0.712 0.288 0.000
S06 Intracranial injury
0.712 0.288 0.000
R30.0 Dysuria
0.712 0.288 0.000
M22 Disorders of patella
0.711 0.288 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.711 0.289 0.000
T81.9 Unspecified complication of procedure
0.711 0.289 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.711 0.289 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.711 0.289 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.711 0.289 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.711 0.289 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.710 0.290 0.000
Y83.4 Other reconstructive surgery
0.710 0.290 0.000
G96 Other disorders of central nervous system
0.710 0.290 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.710 0.290 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.710 0.290 0.000
L60-L75 Disorders of skin appendages
0.709 0.291 0.000
M11 Other crystal arthropathies
0.708 0.292 0.000
M54 Dorsalgia
0.707 0.293 0.000
R39.2 Extrarenal uraemia
0.707 0.293 0.000
R39.0 Extravasation of urine
0.707 0.293 0.000
M35 Other systemic involvement of connective tissue
0.707 0.293 0.000
N20.9 Urinary calculus, unspecified
0.707 0.293 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.706 0.294 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.706 0.294 0.000
M34 Systemic sclerosis
0.706 0.294 0.000
M33 Dermatopolymyositis
0.706 0.294 0.000
M32 Systemic lupus erythematosus
0.706 0.294 0.000
M30 Polyarteritis nodosa and related conditions
0.706 0.294 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.705 0.295 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.704 0.296 0.000
M19.0 Primary arthrosis of other joints
0.703 0.297 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.702 0.297 0.000
H10-H13 Disorders of conjunctiva
0.702 0.297 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
D64 Other anaemias
0.702 0.298 0.000
G70-G73 Diseases of myoneural junction and muscle
0.701 0.299 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.701 0.299 0.000
Q60-Q64 Congenital malformations of the urinary system
0.700 0.300 0.000
R94.3 Abnormal results of cardiovascular function studies
0.699 0.301 0.000
N99-N99 Other disorders of the genitourinary system
0.699 0.301 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.699 0.301 0.000
O72 Postpartum haemorrhage
0.699 0.301 0.000
G81 Hemiplegia
0.698 0.301 0.000
S81.9 Open wound of lower leg, part unspecified
0.698 0.302 0.000
G93.0 Cerebral cysts
0.698 0.302 0.000
O80-O84 Delivery
0.696 0.304 0.000
S80.0 Contusion of knee
0.694 0.306 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.693 0.307 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.692 0.308 0.000
L10-L14 Bullous disorders
0.691 0.308 0.000
G82 Paraplegia and tetraplegia
0.691 0.308 0.000
H66 Suppurative and unspecified otitis media
0.691 0.309 0.000
Y52 Agents primarily affecting the cardiovascular system
0.689 0.310 0.000
H18 Other disorders of cornea
0.689 0.311 0.000
S62 Fracture at wrist and hand level
0.689 0.311 0.000
B35-B49 Mycoses
0.689 0.311 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.689 0.311 0.000
S89 Other and unspecified injuries of lower leg
0.688 0.312 0.000
S88 Traumatic amputation of lower leg
0.688 0.312 0.000
S87 Crushing injury of lower leg
0.688 0.312 0.000
S86 Injury of muscle and tendon at lower leg level
0.688 0.312 0.000
S85 Injury of blood vessels at lower leg level
0.688 0.312 0.000
S84 Injury of nerves at lower leg level
0.688 0.312 0.000
H53 Visual disturbances
0.687 0.313 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.687 0.313 0.000
R01 Cardiac murmurs and other cardiac sounds
0.687 0.313 0.000
M06.8 Other specified rheumatoid arthritis
0.686 0.314 0.000
M06.3 Rheumatoid nodule
0.686 0.314 0.000
M06.2 Rheumatoid bursitis
0.686 0.314 0.000
M06.1 Adult-onset Still's disease
0.686 0.314 0.000
M06.0 Seronegative rheumatoid arthritis
0.686 0.314 0.000
H00 Hordeolum and chalazion
0.686 0.314 0.000
E11 Non-insulin-dependent diabetes mellitus
0.685 0.315 0.000
S69 Other and unspecified injuries of wrist and hand
0.685 0.315 0.000
S67 Crushing injury of wrist and hand
0.685 0.315 0.000
S65 Injury of blood vessels at wrist and hand level
0.685 0.315 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.685 0.315 0.000
M13.94 Arthritis, unspecified (Hand)
0.685 0.315 0.000
H55 Nystagmus and other irregular eye movements
0.685 0.315 0.000
M79.0 Rheumatism, unspecified
0.684 0.316 0.000
R06.8 Other and unspecified abnormalities of breathing
0.684 0.316 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.683 0.317 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.683 0.317 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.683 0.317 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.682 0.317 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.682 0.318 0.000
R47-R49 Symptoms and signs involving speech and voice
0.682 0.318 0.000
S01 Open wound of head
0.682 0.318 0.000
J60-J70 Lung diseases due to external agents
0.681 0.319 0.000
M23.9 Internal derangement of knee, unspecified
0.681 0.319 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.681 0.319 0.000
M23.5 Chronic instability of knee
0.681 0.319 0.000
M23.4 Loose body in knee
0.681 0.319 0.000
M23.1 Discoid meniscus (congenital)
0.681 0.319 0.000
M23.0 Cystic meniscus
0.681 0.319 0.000
R04.0 Epistaxis
0.680 0.320 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.680 0.320 0.000
R06.4 Hyperventilation
0.679 0.321 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.678 0.322 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.678 0.322 0.000
A30-A49 Other bacterial diseases
0.678 0.322 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.678 0.322 0.000
M65.3 Trigger finger
0.677 0.323 0.000
L40-L45 Papulosquamous disorders
0.676 0.324 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.676 0.324 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
W29 Contact with other powered hand tools and household machinery
0.675 0.325 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.674 0.326 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.673 0.327 0.000
K43 Ventral hernia
0.673 0.327 0.000
R06.2 Wheezing
0.672 0.328 0.000
J30-J39 Other diseases of upper respiratory tract
0.672 0.328 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.672 0.328 0.000
G57 Mononeuropathies of lower limb
0.672 0.328 0.000
N21 Calculus of lower urinary tract
0.671 0.329 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.671 0.329 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.671 0.329 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.670 0.330 0.000
G95 Other diseases of spinal cord
0.669 0.331 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.669 0.331 0.000
N15 Other renal tubulo-interstitial diseases
0.669 0.331 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.669 0.331 0.000
N11 Chronic tubulo-interstitial nephritis
0.669 0.331 0.000
N10 Acute tubulo-interstitial nephritis
0.669 0.331 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.669 0.331 0.000
O85-O92 Complications predominantly related to the puerperium
0.668 0.331 0.000
M23.8 Other internal derangements of knee
0.668 0.332 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.668 0.332 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.667 0.333 0.000
N64.5 Other signs and symptoms in breast
0.667 0.333 0.000
J00-J06 Acute upper respiratory infections
0.667 0.333 0.000
K50 Crohn's disease [regional enteritis]
0.667 0.333 0.000
G20-G26 Extrapyramidal and movement disorders
0.667 0.333 0.000
H02 Other disorders of eyelid
0.667 0.333 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.667 0.333 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.666 0.334 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.666 0.334 0.000
M41 Scoliosis
0.666 0.334 0.000
S08 Traumatic amputation of part of head
0.665 0.335 0.000
S07 Crushing injury of head
0.665 0.335 0.000
S05 Injury of eye and orbit
0.665 0.335 0.000
S04 Injury of cranial nerves
0.665 0.335 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.665 0.335 0.000
H65 Nonsuppurative otitis media
0.665 0.335 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.665 0.335 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.664 0.335 0.000
L03 Cellulitis
0.664 0.336 0.000
O70 Perineal laceration during delivery
0.664 0.336 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.664 0.336 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.664 0.336 0.000
G90 Disorders of autonomic nervous system
0.664 0.336 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.664 0.336 0.000
G92 Toxic encephalopathy
0.664 0.336 0.000
H90 Conductive and sensorineural hearing loss
0.663 0.337 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.663 0.337 0.000
D64.9 Anaemia, unspecified
0.661 0.339 0.000
S02.2 Fracture of nasal bones
0.660 0.340 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.660 0.340 0.000
S27 Injury of other and unspecified intrathoracic organs
0.660 0.340 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.659 0.340 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.659 0.341 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.659 0.341 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.658 0.342 0.000
K04 Diseases of pulp and periapical tissues
0.658 0.342 0.000
M10.4 Other secondary gout
0.658 0.342 0.000
M10.3 Gout due to impairment of renal function
0.658 0.342 0.000
M10.2 Drug-induced gout
0.658 0.342 0.000
M10.1 Lead-induced gout
0.658 0.342 0.000
M10.0 Idiopathic gout
0.658 0.342 0.000
R09.0 Asphyxia
0.657 0.343 0.000
S00.7 Multiple superficial injuries of head
0.657 0.343 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.656 0.344 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.656 0.344 0.000
K13 Other diseases of lip and oral mucosa
0.656 0.344 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.655 0.345 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.655 0.345 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.655 0.345 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.655 0.345 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.655 0.345 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.655 0.345 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.655 0.345 0.000
M25.57 Pain in joint (Ankle and foot)
0.655 0.345 0.000
Y40 Systemic antibiotics
0.654 0.346 0.000
M23.3 Other meniscus derangements
0.654 0.346 0.000
M13.8 Other specified arthritis
0.653 0.347 0.000
M13.1 Monoarthritis, not elsewhere classified
0.653 0.347 0.000
M13.0 Polyarthritis, unspecified
0.653 0.347 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.653 0.347 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.651 0.348 0.000
L30 Other dermatitis
0.651 0.349 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.650 0.350 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.650 0.350 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.649 0.350 0.000
Z57 Occupational exposure to risk-factors
0.649 0.351 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.649 0.351 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.649 0.351 0.000
Y98 Lifestyle-related condition
0.649 0.351 0.000
Y97 Environmental-pollution-related condition
0.649 0.351 0.000
Y96 Work-related condition
0.649 0.351 0.000
S61.7 Multiple open wounds of wrist and hand
0.649 0.351 0.000
H05 Disorders of orbit
0.649 0.351 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.649 0.351 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.648 0.352 0.000
R94.7 Abnormal results of other endocrine function studies
0.648 0.352 0.000
R94.6 Abnormal results of thyroid function studies
0.648 0.352 0.000
R94.4 Abnormal results of kidney function studies
0.648 0.352 0.000
R94.2 Abnormal results of pulmonary function studies
0.648 0.352 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.648 0.352 0.000
R94.0 Abnormal results of function studies of central nervous system
0.648 0.352 0.000
G40-G47 Episodic and paroxysmal disorders
0.646 0.354 0.000
M85 Other disorders of bone density and structure
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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