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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76681384
log Bayes Factor = 14.081
Chromosome 1   position 231,134,798  (GRCh37) Explore rs76681384 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.995 0.005 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.994 0.006 0.000
M20-M25 Other joint disorders
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
Chapter II Neoplasms
0.984 0.016 0.000
M15-M19 Arthrosis
0.983 0.017 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.983 0.017 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.982 0.018 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.982 0.018 0.000
M16 Coxarthrosis [arthrosis of hip]
0.981 0.019 0.000
M23 Internal derangement of knee
0.981 0.019 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
Chapter IX Diseases of the circulatory system
0.979 0.021 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.977 0.023 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.977 0.023 0.000
I60-I69 Cerebrovascular diseases
0.974 0.026 0.000
M23.3 Other meniscus derangements
0.972 0.028 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.968 0.032 0.000
M16.9 Coxarthrosis, unspecified
0.967 0.033 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.966 0.034 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.963 0.037 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.958 0.042 0.000
I30-I52 Other forms of heart disease
0.957 0.043 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.952 0.048 0.000
L03 Cellulitis
0.952 0.048 0.000
I63 Cerebral infarction
0.950 0.050 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.949 0.051 0.000
Chapter VI Diseases of the nervous system
0.943 0.057 0.000
M25 Other joint disorders, not elsewhere classified
0.940 0.060 0.000
M16.1 Other primary coxarthrosis
0.939 0.061 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.938 0.062 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.933 0.067 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.927 0.073 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.926 0.074 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.926 0.074 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.925 0.075 0.000
Chapter V Mental and behavioural disorders
0.924 0.076 0.000
I63.9 Cerebral infarction, unspecified
0.921 0.079 0.000
H53-H54 Visual disturbances and blindness
0.921 0.079 0.000
Z87 Personal history of other diseases and conditions
0.916 0.084 0.000
A30-A49 Other bacterial diseases
0.914 0.086 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.907 0.093 0.000
S20-S29 Injuries to the thorax
0.907 0.093 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.906 0.094 0.000
D00-D09 In situ neoplasms
0.901 0.099 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.899 0.101 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.897 0.103 0.000
B95-B98 Bacterial, viral and other infectious agents
0.896 0.104 0.000
H53 Visual disturbances
0.891 0.109 0.000
Z87.1 Personal history of diseases of the digestive system
0.890 0.110 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.885 0.115 0.000
Y43 Primarily systemic agents
0.877 0.123 0.000
Z92 Personal history of medical treatment
0.876 0.124 0.000
L03.1 Cellulitis of other parts of limb
0.875 0.125 0.000
C15-C26 Malignant neoplasms of digestive organs
0.869 0.131 0.000
Z13 Special screening examination for other diseases and disorders
0.869 0.131 0.000
W20-W49 Exposure to inanimate mechanical forces
0.868 0.132 0.000
H30-H36 Disorders of choroid and retina
0.868 0.132 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.867 0.133 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.866 0.134 0.000
A41 Other septicaemia
0.865 0.135 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.860 0.140 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.859 0.141 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.859 0.141 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.857 0.143 0.000
M24 Other specific joint derangements
0.855 0.145 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.854 0.146 0.000
I35 Nonrheumatic aortic valve disorders
0.852 0.148 0.000
M25.4 Effusion of joint
0.852 0.148 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.851 0.149 0.000
I38 Endocarditis, valve unspecified
0.851 0.149 0.000
M91-M94 Chondropathies
0.850 0.150 0.000
T81 Complications of procedures, not elsewhere classified
0.846 0.154 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.845 0.155 0.000
C43 Malignant melanoma of skin
0.844 0.156 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.839 0.161 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.839 0.161 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.833 0.167 0.000
I45 Other conduction disorders
0.830 0.170 0.000
H35 Other retinal disorders
0.828 0.172 0.000
C83.3 Large cell (diffuse)
0.825 0.175 0.000
Z89 Acquired absence of limb
0.825 0.175 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.824 0.176 0.000
Y83.4 Other reconstructive surgery
0.823 0.177 0.000
Z29 Need for other prophylactic measures
0.823 0.177 0.000
Z95.2 Presence of prosthetic heart valve
0.822 0.178 0.000
C44 Other malignant neoplasms of skin
0.822 0.178 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.821 0.179 0.000
Z13.9 Special screening examination, unspecified
0.821 0.179 0.000
T66-T78 Other and unspecified effects of external causes
0.819 0.181 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.819 0.181 0.000
D06 Carcinoma in situ of cervix uteri
0.817 0.183 0.000
F30-F39 Mood [affective] disorders
0.816 0.184 0.000
Y43.3 Other antineoplastic drugs
0.815 0.185 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.811 0.189 0.000
I51 Complications and ill-defined descriptions of heart disease
0.809 0.191 0.000
L90 Atrophic disorders of skin
0.809 0.191 0.000
Y86 Sequelae of other accidents
0.808 0.192 0.000
B35-B49 Mycoses
0.808 0.192 0.000
T82.3 Mechanical complication of other vascular grafts
0.806 0.194 0.000
M25.7 Osteophyte
0.805 0.195 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.803 0.196 0.000
Y85 Sequelae of transport accidents
0.802 0.198 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.801 0.199 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.797 0.203 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.797 0.203 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.796 0.204 0.000
B65-B83 Helminthiases
0.794 0.206 0.000
H53.9 Visual disturbance, unspecified
0.793 0.207 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.791 0.209 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.789 0.211 0.000
I69 Sequelae of cerebrovascular disease
0.789 0.211 0.000
L03.2 Cellulitis of face
0.789 0.211 0.000
M25.46 Effusion of joint (Lower leg)
0.788 0.212 0.000
S40-S49 Injuries to the shoulder and upper arm
0.786 0.214 0.000
L03.3 Cellulitis of trunk
0.786 0.214 0.000
G40-G47 Episodic and paroxysmal disorders
0.784 0.216 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
H53.1 Subjective visual disturbances
0.781 0.219 0.000
L03.0 Cellulitis of finger and toe
0.780 0.220 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.780 0.220 0.000
G20-G26 Extrapyramidal and movement disorders
0.779 0.221 0.000
S27 Injury of other and unspecified intrathoracic organs
0.778 0.222 0.000
L90.5 Scar conditions and fibrosis of skin
0.777 0.223 0.000
X60-X84 Intentional self-harm
0.776 0.224 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.775 0.225 0.000
H53.8 Other visual disturbances
0.774 0.226 0.000
C44.6 Skin of upper limb, including shoulder
0.774 0.226 0.000
I44 Atrioventricular and left bundle-branch block
0.774 0.226 0.000
C92 Myeloid leukaemia
0.774 0.226 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.226 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.772 0.228 0.000
Z99.3 Dependence on wheelchair
0.772 0.228 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.772 0.228 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.771 0.229 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.771 0.229 0.000
I62 Other nontraumatic intracranial haemorrhage
0.771 0.229 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.771 0.229 0.000
C25 Malignant neoplasm of pancreas
0.770 0.230 0.000
Z90.8 Acquired absence of other organs
0.770 0.230 0.000
I60 Subarachnoid haemorrhage
0.770 0.230 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.770 0.230 0.000
Y83.5 Amputation of limb(s)
0.765 0.234 0.000
I35.1 Aortic (valve) insufficiency
0.765 0.235 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.764 0.236 0.000
T79-T79 Certain early complications of trauma
0.764 0.236 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.764 0.236 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.762 0.238 0.000
M16.7 Other secondary coxarthrosis
0.761 0.239 0.000
T82.1 Mechanical complication of cardiac electronic device
0.761 0.239 0.000
Z87.0 Personal history of diseases of the respiratory system
0.760 0.240 0.000
Z90.5 Acquired absence of kidney
0.759 0.241 0.000
D06.9 Cervix, unspecified
0.757 0.243 0.000
Z90.3 Acquired absence of part of stomach
0.757 0.243 0.000
M24.1 Other articular cartilage disorders
0.756 0.244 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.755 0.244 0.000
Chapter XXII Codes for special purposes
0.755 0.245 0.000
Z95.0 Presence of cardiac pacemaker
0.754 0.246 0.000
D50-D53 Nutritional anaemias
0.753 0.247 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.752 0.248 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.752 0.248 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.751 0.249 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.748 0.251 0.000
M05-M14 Inflammatory polyarthropathies
0.748 0.252 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.747 0.253 0.000
W00-W19 Falls
0.747 0.253 0.000
C91 Lymphoid leukaemia
0.746 0.253 0.000
A80-A89 Viral infections of the central nervous system
0.746 0.254 0.000
F80-F89 Disorders of psychological development
0.746 0.254 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.745 0.255 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.744 0.256 0.000
I51.7 Cardiomegaly
0.744 0.256 0.000
L20-L30 Dermatitis and eczema
0.744 0.256 0.000
M80-M85 Disorders of bone density and structure
0.743 0.257 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.742 0.258 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.741 0.259 0.000
I67 Other cerebrovascular diseases
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.741 0.259 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.740 0.260 0.000
Z11.2 Special screening examination for other bacterial diseases
0.740 0.260 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.739 0.261 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.737 0.263 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.736 0.264 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.736 0.264 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.735 0.265 0.000
S70-S79 Injuries to the hip and thigh
0.735 0.265 0.000
G81 Hemiplegia
0.734 0.266 0.000
A41.9 Septicaemia, unspecified
0.734 0.266 0.000
Z80 Family history of malignant neoplasm
0.734 0.266 0.000
I05-I09 Chronic rheumatic heart diseases
0.733 0.267 0.000
T86 Failure and rejection of transplanted organs and tissues
0.731 0.269 0.000
G43 Migraine
0.729 0.271 0.000
W25 Contact with sharp glass
0.729 0.271 0.000
H35.8 Other specified retinal disorders
0.729 0.271 0.000
I61 Intracerebral haemorrhage
0.728 0.272 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.728 0.272 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.727 0.273 0.000
E10-E14 Diabetes mellitus
0.727 0.273 0.000
M21 Other acquired deformities of limbs
0.727 0.273 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.726 0.274 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.725 0.275 0.000
M23.4 Loose body in knee
0.724 0.276 0.000
S80-S89 Injuries to the knee and lower leg
0.723 0.277 0.000
I34 Nonrheumatic mitral valve disorders
0.722 0.278 0.000
Z29.2 Other prophylactic chemotherapy
0.721 0.279 0.000
M16.0 Primary coxarthrosis, bilateral
0.721 0.279 0.000
H40-H42 Glaucoma
0.720 0.280 0.000
Y45.1 Salicylates
0.720 0.280 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.720 0.280 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
F31 Bipolar affective disorder
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
I47 Paroxysmal tachycardia
0.715 0.285 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.714 0.286 0.000
Z04 Examination and observation for other reasons
0.713 0.286 0.000
Z10 Routine general health check-up of defined subpopulation
0.713 0.287 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.713 0.287 0.000
Z09.4 Follow-up examination after treatment of fracture
0.713 0.287 0.000
Z09.3 Follow-up examination after psychotherapy
0.713 0.287 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.713 0.287 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M34 Systemic sclerosis
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
H10-H13 Disorders of conjunctiva
0.712 0.288 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.712 0.288 0.000
I33 Acute and subacute endocarditis
0.712 0.288 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.712 0.288 0.000
M23.8 Other internal derangements of knee
0.711 0.288 0.000
M45-M49 Spondylopathies
0.711 0.289 0.000
H53.2 Diplopia
0.711 0.289 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.711 0.289 0.000
Z90.2 Acquired absence of lung [part of]
0.711 0.289 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.710 0.290 0.000
Y83.0 Surgical operation with transplant of whole organ
0.710 0.290 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.709 0.291 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.708 0.292 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.707 0.293 0.000
D04 Carcinoma in situ of skin
0.706 0.294 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
H35.2 Other proliferative retinopathy
0.706 0.294 0.000
D60-D64 Aplastic and other anaemias
0.706 0.294 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.706 0.294 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.706 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.706 0.294 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
Z22 Carrier of infectious disease
0.705 0.295 0.000
M19 Other arthrosis
0.705 0.295 0.000
M15 Polyarthrosis
0.705 0.295 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.704 0.295 0.000
C81 Hodgkin's disease
0.704 0.296 0.000
Z92.0 Personal history of contraception
0.704 0.296 0.000
M50-M54 Other dorsopathies
0.704 0.296 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.704 0.296 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.704 0.296 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.704 0.296 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.704 0.296 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.704 0.296 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.704 0.296 0.000
E20-E35 Disorders of other endocrine glands
0.704 0.296 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.703 0.296 0.000
M16.5 Other posttraumatic coxarthrosis
0.703 0.296 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.703 0.296 0.000
M16.3 Other dysplastic coxarthrosis
0.703 0.296 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.703 0.296 0.000
M23.9 Internal derangement of knee, unspecified
0.703 0.297 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.703 0.297 0.000
M23.5 Chronic instability of knee
0.703 0.297 0.000
M23.1 Discoid meniscus (congenital)
0.703 0.297 0.000
M23.0 Cystic meniscus
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.702 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.297 0.000
B50-B64 Protozoal diseases
0.702 0.297 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.297 0.000
A75-A79 Rickettsioses
0.702 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.297 0.000
A65-A69 Other spirochaetal diseases
0.702 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.297 0.000
A15-A19 Tuberculosis
0.702 0.297 0.000
I00-I02 Acute rheumatic fever
0.702 0.298 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.702 0.298 0.000
L04 Acute lymphadenitis
0.700 0.299 0.000
L01 Impetigo
0.700 0.299 0.000
L00 Staphylococcal scalded skin syndrome
0.700 0.299 0.000
Z84 Family history of other conditions
0.700 0.300 0.000
Z81 Family history of mental and behavioural disorders
0.700 0.300 0.000
Q60-Q64 Congenital malformations of the urinary system
0.700 0.300 0.000
Y40 Systemic antibiotics
0.700 0.300 0.000
L85 Other epidermal thickening
0.700 0.300 0.000
I44.2 Atrioventricular block, complete
0.699 0.301 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.698 0.302 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.698 0.302 0.000
I30 Acute pericarditis
0.698 0.302 0.000
Z90.0 Acquired absence of part of head and neck
0.698 0.302 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.697 0.303 0.000
M23.37 Other meniscus derangements-Capsular lig
0.697 0.303 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.697 0.303 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.697 0.303 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.697 0.303 0.000
B25-B34 Other viral diseases
0.696 0.304 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.694 0.306 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.694 0.306 0.000
C95 Leukaemia of unspecified cell type
0.694 0.306 0.000
C94 Other leukaemias of specified cell type
0.694 0.306 0.000
C93 Monocytic leukaemia
0.694 0.306 0.000
C88 Malignant immunoproliferative diseases
0.694 0.306 0.000
C86 Other specified types of T/NK-cell lymphoma
0.694 0.306 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.694 0.306 0.000
Z94 Transplanted organ and tissue status
0.694 0.306 0.000
M25.5 Pain in joint
0.693 0.307 0.000
I45.8 Other specified conduction disorders
0.691 0.309 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.691 0.309 0.000
Y59 Other and unspecified vaccines and biological substances
0.690 0.310 0.000
Y58 Bacterial vaccines
0.690 0.310 0.000
Y57 Other and unspecified drugs and medicaments
0.690 0.310 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.690 0.310 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.310 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.690 0.310 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.690 0.310 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.690 0.310 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
Y48 Anaesthetics and therapeutic gases
0.690 0.310 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.690 0.310 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.690 0.310 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.690 0.310 0.000
M92 Other juvenile osteochondrosis
0.690 0.310 0.000
C85.1 B-cell lymphoma, unspecified
0.690 0.310 0.000
T78 Adverse effects, not elsewhere classified
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.311 0.000
I51.0 Cardiac septal defect, acquired
0.688 0.312 0.000
T92 Sequelae of injuries of upper limb
0.688 0.312 0.000
Y88 Sequelae of surgical and medical care as external cause
0.687 0.313 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.687 0.313 0.000
S27.0 Traumatic pneumothorax
0.687 0.313 0.000
C43.5 Malignant melanoma of trunk
0.686 0.314 0.000
I52 Other heart disorders in diseases classified elsewhere
0.686 0.314 0.000
I48 Atrial fibrillation and flutter
0.686 0.314 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.686 0.314 0.000
I41 Myocarditis in diseases classified elsewhere
0.686 0.314 0.000
I40 Acute myocarditis
0.686 0.314 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.686 0.314 0.000
I37 Pulmonary valve disorders
0.686 0.314 0.000
I36 Nonrheumatic tricuspid valve disorders
0.686 0.314 0.000
I32 Pericarditis in diseases classified elsewhere
0.686 0.314 0.000
Z99.1 Dependence on respirator
0.686 0.314 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.685 0.314 0.000
I46 Cardiac arrest
0.685 0.315 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.684 0.316 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.684 0.316 0.000
L03.8 Cellulitis of other sites
0.682 0.318 0.000
L03.9 Cellulitis, unspecified
0.682 0.318 0.000
I63.8 Other cerebral infarction
0.681 0.319 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.681 0.319 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.681 0.319 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.681 0.319 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.681 0.319 0.000
I49 Other cardiac arrhythmias
0.681 0.319 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.680 0.319 0.000
Y83.6 Removal of other organ (partial) (total)
0.680 0.320 0.000
T88.5 Other complications of anaesthesia
0.680 0.320 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.678 0.322 0.000
W22 Striking against or struck by other objects
0.677 0.323 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.676 0.324 0.000
G43.9 Migraine, unspecified
0.676 0.324 0.000
Z95.4 Presence of other heart-valve replacement
0.675 0.325 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.675 0.325 0.000
H43-H45 Disorders of vitreous body and globe
0.675 0.325 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.674 0.326 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.674 0.326 0.000
M25.9 Joint disorder, unspecified
0.674 0.326 0.000
M25.8 Other specified joint disorders
0.674 0.326 0.000
M25.3 Other instability of joint
0.674 0.326 0.000
M25.2 Flail joint
0.674 0.326 0.000
M25.1 Fistula of joint
0.674 0.326 0.000
M25.0 Haemarthrosis
0.674 0.326 0.000
B35 Dermatophytosis
0.674 0.326 0.000
H36 Retinal disorders in diseases classified elsewhere
0.674 0.326 0.000
D05 Carcinoma in situ of breast
0.674 0.326 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.673 0.327 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.672 0.328 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.672 0.328 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.672 0.328 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.672 0.328 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.671 0.328 0.000
H35.3 Degeneration of macula and posterior pole
0.672 0.328 0.000
S50-S59 Injuries to the elbow and forearm
0.671 0.329 0.000
M40-M43 Deforming dorsopathies
0.671 0.329 0.000
C15 Malignant neoplasm of oesophagus
0.670 0.330 0.000
B15-B19 Viral hepatitis
0.669 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.669 0.331 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.668 0.332 0.000
W21 Striking against or struck by sports equipment
0.668 0.332 0.000
H25-H28 Disorders of lens
0.668 0.332 0.000
E10 Insulin-dependent diabetes mellitus
0.668 0.332 0.000
C44.7 Skin of lower limb, including hip
0.666 0.334 0.000
A49 Bacterial infection of unspecified site
0.666 0.334 0.000
L84 Corns and callosities
0.665 0.335 0.000
Y89 Sequelae of other external causes
0.665 0.335 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.665 0.335 0.000
Z97 Presence of other devices
0.665 0.335 0.000
Z89.4 Acquired absence of foot and ankle
0.664 0.336 0.000
C16 Malignant neoplasm of stomach
0.664 0.336 0.000
D69 Purpura and other haemorrhagic conditions
0.663 0.336 0.000
D55-D59 Haemolytic anaemias
0.663 0.337 0.000
G81.9 Hemiplegia, unspecified
0.663 0.337 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.663 0.337 0.000
F70-F79 Mental retardation
0.663 0.337 0.000
F60-F69 Disorders of adult personality and behaviour
0.663 0.337 0.000
M22 Disorders of patella
0.662 0.337 0.000
D68 Other coagulation defects
0.662 0.338 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.662 0.338 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.339 0.000
H35.0 Background retinopathy and retinal vascular changes
0.661 0.339 0.000
C25.0 Head of pancreas
0.661 0.339 0.000
B80 Enterobiasis
0.660 0.340 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.659 0.340 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.659 0.341 0.000
M31 Other necrotising vasculopathies
0.659 0.341 0.000
L90.0 Lichen sclerosus et atrophicus
0.659 0.341 0.000
M94 Other disorders of cartilage
0.658 0.342 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.658 0.342 0.000
F32 Depressive episode
0.657 0.343 0.000
I45.1 Other and unspecified right bundle-branch block
0.657 0.343 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.657 0.343 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.657 0.343 0.000
D09 Carcinoma in situ of other and unspecified sites
0.657 0.343 0.000
C21 Malignant neoplasm of anus and anal canal
0.656 0.343 0.000
A48 Other bacterial diseases, not elsewhere classified
0.655 0.345 0.000
A44 Bartonellosis
0.655 0.345 0.000
A43 Nocardiosis
0.655 0.345 0.000
A42 Actinomycosis
0.655 0.345 0.000
A40 Streptococcal septicaemia
0.655 0.345 0.000
A39 Meningococcal infection
0.655 0.345 0.000
A37 Whooping cough
0.655 0.345 0.000
A36 Diphtheria
0.655 0.345 0.000
A32 Listeriosis
0.655 0.345 0.000
A31 Infection due to other mycobacteria
0.655 0.345 0.000
A30 Leprosy [Hansen's disease]
0.655 0.345 0.000
A46 Erysipelas
0.655 0.345 0.000
A38 Scarlet fever
0.655 0.345 0.000
A35 Other tetanus
0.655 0.345 0.000
A34 Obstetrical tetanus
0.655 0.345 0.000
A33 Tetanus neonatorum
0.655 0.345 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.655 0.345 0.000
G30-G32 Other degenerative diseases of the nervous system
0.655 0.345 0.000
C44.5 Skin of trunk
0.655 0.345 0.000
H55-H59 Other disorders of eye and adnexa
0.654 0.346 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.654 0.346 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.654 0.346 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.652 0.347 0.000
S22.0 Fracture of thoracic vertebra
0.652 0.348 0.000
S00-S09 Injuries to the head
0.651 0.349 0.000
Z83 Family history of other specific disorders
0.651 0.349 0.000
Z28 Immunisation not carried out
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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