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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10491777
log Bayes Factor = 15.847
Chromosome 9   position 14,352,001  (GRCh37) Explore rs10491777 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
J34 Other disorders of nose and nasal sinuses
0.998 0.002 0.000
J33 Nasal polyp
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
W00-W19 Falls
0.994 0.006 0.000
N40-N51 Diseases of male genital organs
0.990 0.010 0.000
Chapter IX Diseases of the circulatory system
0.989 0.011 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.988 0.012 0.000
J33.9 Nasal polyp, unspecified
0.985 0.015 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.985 0.015 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
W19 Unspecified fall
0.981 0.019 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.980 0.020 0.000
N20-N23 Urolithiasis
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.972 0.028 0.000
W19.9 Unspecified place
0.970 0.030 0.000
I50 Heart failure
0.965 0.035 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.958 0.042 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.952 0.048 0.000
N10-N16 Renal tubulo-interstitial diseases
0.946 0.054 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.944 0.056 0.000
N48 Other disorders of penis
0.944 0.056 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.942 0.058 0.000
J34.2 Deviated nasal septum
0.941 0.059 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.938 0.062 0.000
J33.0 Polyp of nasal cavity
0.936 0.064 0.000
N23 Unspecified renal colic
0.932 0.068 0.000
I44 Atrioventricular and left bundle-branch block
0.931 0.069 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.928 0.072 0.000
N42 Other disorders of prostate
0.927 0.073 0.000
I60-I69 Cerebrovascular diseases
0.925 0.075 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.923 0.077 0.000
I50.1 Left ventricular failure
0.919 0.081 0.000
N13 Obstructive and reflux uropathy
0.909 0.091 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.907 0.093 0.000
T66-T78 Other and unspecified effects of external causes
0.905 0.094 0.000
S80-S89 Injuries to the knee and lower leg
0.904 0.096 0.000
M05-M14 Inflammatory polyarthropathies
0.904 0.096 0.000
M20-M25 Other joint disorders
0.899 0.101 0.000
F30-F39 Mood [affective] disorders
0.899 0.101 0.000
I50.9 Heart failure, unspecified
0.899 0.101 0.000
I44.2 Atrioventricular block, complete
0.892 0.108 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.889 0.111 0.000
Chapter VII Diseases of the eye and adnexa
0.888 0.112 0.000
M15-M19 Arthrosis
0.888 0.112 0.000
N60-N64 Disorders of breast
0.887 0.113 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.884 0.116 0.000
N20 Calculus of kidney and ureter
0.880 0.120 0.000
M45-M49 Spondylopathies
0.879 0.121 0.000
Chapter VIII Diseases of the ear and mastoid process
0.879 0.121 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.871 0.129 0.000
Y40 Systemic antibiotics
0.870 0.130 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.869 0.131 0.000
D69 Purpura and other haemorrhagic conditions
0.869 0.131 0.000
N00-N08 Glomerular diseases
0.867 0.133 0.000
N48.1 Balanoposthitis
0.867 0.133 0.000
I69 Sequelae of cerebrovascular disease
0.867 0.133 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.866 0.134 0.000
J35 Chronic diseases of tonsils and adenoids
0.865 0.135 0.000
F05.9 Delirium, unspecified
0.861 0.139 0.000
J39 Other diseases of upper respiratory tract
0.859 0.141 0.000
J84 Other interstitial pulmonary diseases
0.855 0.145 0.000
J36 Peritonsillar abscess
0.855 0.145 0.000
I72 Other aneurysm
0.854 0.146 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.852 0.148 0.000
H30-H36 Disorders of choroid and retina
0.850 0.150 0.000
M31 Other necrotising vasculopathies
0.849 0.151 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.849 0.151 0.000
I50.0 Congestive heart failure
0.844 0.156 0.000
O00-O08 Pregnancy with abortive outcome
0.844 0.156 0.000
J34.3 Hypertrophy of nasal turbinates
0.842 0.158 0.000
N42.8 Other specified disorders of prostate
0.841 0.159 0.000
F31 Bipolar affective disorder
0.841 0.159 0.000
D60-D64 Aplastic and other anaemias
0.839 0.161 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.839 0.161 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.838 0.162 0.000
N50 Other disorders of male genital organs
0.836 0.164 0.000
N48.6 Balanitis xerotica obliterans
0.833 0.167 0.000
J33.8 Other polyp of sinus
0.832 0.168 0.000
N62 Hypertrophy of breast
0.832 0.168 0.000
Y52 Agents primarily affecting the cardiovascular system
0.831 0.169 0.000
S70-S79 Injuries to the hip and thigh
0.830 0.170 0.000
Chapter XXII Codes for special purposes
0.830 0.170 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.829 0.171 0.000
W07 Fall involving chair
0.827 0.173 0.000
J81 Pulmonary oedema
0.826 0.174 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.823 0.177 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.822 0.178 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.822 0.178 0.000
I71 Aortic aneurysm and dissection
0.818 0.182 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.818 0.182 0.000
W13 Fall from, out of or through building or structure
0.818 0.182 0.000
O03 Spontaneous abortion
0.817 0.183 0.000
N43 Hydrocele and spermatocele
0.814 0.186 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.813 0.187 0.000
I74 Arterial embolism and thrombosis
0.810 0.190 0.000
S80 Superficial injury of lower leg
0.809 0.191 0.000
D55-D59 Haemolytic anaemias
0.809 0.191 0.000
Chapter I Certain infectious and parasitic diseases
0.808 0.192 0.000
I69.3 Sequelae of cerebral infarction
0.806 0.194 0.000
S00-S09 Injuries to the head
0.806 0.194 0.000
M31.6 Other giant cell arteritis
0.805 0.195 0.000
I05-I09 Chronic rheumatic heart diseases
0.805 0.195 0.000
F99-F99 Unspecified mental disorder
0.805 0.195 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.800 0.200 0.000
M17 Gonarthrosis [arthrosis of knee]
0.797 0.203 0.000
Y40.0 Penicillins
0.796 0.204 0.000
W20-W49 Exposure to inanimate mechanical forces
0.795 0.205 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.795 0.205 0.000
H80-H83 Diseases of inner ear
0.793 0.207 0.000
M60-M63 Disorders of muscles
0.792 0.208 0.000
N20.0 Calculus of kidney
0.792 0.208 0.000
W10 Fall on and from stairs and steps
0.792 0.208 0.000
M22 Disorders of patella
0.791 0.209 0.000
W19.2 School, other institution and public administrative area
0.790 0.209 0.000
H36 Retinal disorders in diseases classified elsewhere
0.790 0.210 0.000
F60-F69 Disorders of adult personality and behaviour
0.789 0.211 0.000
T68 Hypothermia
0.789 0.211 0.000
I44.7 Left bundle-branch block, unspecified
0.787 0.213 0.000
I46 Cardiac arrest
0.782 0.218 0.000
H90-H95 Other disorders of ear
0.782 0.218 0.000
M17.1 Other primary gonarthrosis
0.780 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.780 0.220 0.000
I72.4 Aneurysm of artery of lower extremity
0.779 0.221 0.000
D68 Other coagulation defects
0.777 0.223 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.776 0.224 0.000
I60 Subarachnoid haemorrhage
0.775 0.225 0.000
I36 Nonrheumatic tricuspid valve disorders
0.775 0.225 0.000
H43-H45 Disorders of vitreous body and globe
0.775 0.225 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.774 0.225 0.000
F17.2 Dependence syndrome
0.774 0.226 0.000
J39.2 Other diseases of pharynx
0.774 0.226 0.000
D50-D53 Nutritional anaemias
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.773 0.227 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.772 0.228 0.000
J35.0 Chronic tonsillitis
0.770 0.230 0.000
M25 Other joint disorders, not elsewhere classified
0.768 0.232 0.000
I33 Acute and subacute endocarditis
0.768 0.232 0.000
F31.9 Bipolar affective disorder, unspecified
0.767 0.233 0.000
J60-J70 Lung diseases due to external agents
0.766 0.234 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.764 0.236 0.000
O03.4 Incomplete, without complication
0.763 0.237 0.000
N50.8 Other specified disorders of male genital organs
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.762 0.238 0.000
N13.4 Hydroureter
0.761 0.239 0.000
Chapter VI Diseases of the nervous system
0.761 0.239 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.760 0.240 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.759 0.241 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.758 0.242 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.758 0.242 0.000
M47 Spondylosis
0.758 0.242 0.000
T78 Adverse effects, not elsewhere classified
0.757 0.243 0.000
D66 Hereditary factor VIII deficiency
0.757 0.243 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.756 0.244 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.756 0.244 0.000
N64 Other disorders of breast
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.755 0.245 0.000
D80-D89 Certain disorders involving the immune mechanism
0.753 0.247 0.000
S60-S69 Injuries to the wrist and hand
0.753 0.247 0.000
F80-F89 Disorders of psychological development
0.752 0.248 0.000
T86 Failure and rejection of transplanted organs and tissues
0.752 0.248 0.000
I38 Endocarditis, valve unspecified
0.752 0.248 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.751 0.249 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.750 0.250 0.000
H81 Disorders of vestibular function
0.749 0.251 0.000
I27 Other pulmonary heart diseases
0.748 0.252 0.000
H36.0 Diabetic retinopathy
0.748 0.252 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.747 0.253 0.000
F40 Phobic anxiety disorders
0.747 0.253 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.742 0.258 0.000
N42.0 Calculus of prostate
0.742 0.258 0.000
T36 Poisoning by systemic antibiotics
0.742 0.258 0.000
Y44 Agents primarily affecting blood constituents
0.741 0.259 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.740 0.260 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.740 0.260 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.740 0.260 0.000
T90 Sequelae of injuries of head
0.738 0.262 0.000
O03.9 Complete or unspecified, without complication
0.738 0.262 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.737 0.263 0.000
N63 Unspecified lump in breast
0.737 0.263 0.000
N13.6 Pyonephrosis
0.737 0.263 0.000
X60-X84 Intentional self-harm
0.736 0.264 0.000
M24 Other specific joint derangements
0.734 0.265 0.000
S82 Fracture of lower leg, including ankle
0.734 0.266 0.000
N17-N19 Renal failure
0.732 0.268 0.000
N45 Orchitis and epididymitis
0.731 0.269 0.000
W19.3 Sports and athletics area
0.731 0.269 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.731 0.269 0.000
Y57 Other and unspecified drugs and medicaments
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.727 0.272 0.000
T43.2 Other and unspecified antidepressants
0.727 0.273 0.000
M86-M90 Other osteopathies
0.726 0.274 0.000
M10 Gout
0.726 0.274 0.000
J00-J06 Acute upper respiratory infections
0.726 0.274 0.000
E10-E14 Diabetes mellitus
0.725 0.275 0.000
M06 Other rheumatoid arthritis
0.725 0.275 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.724 0.276 0.000
J09-J18 Influenza and pneumonia
0.724 0.276 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.722 0.278 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.719 0.281 0.000
M13 Other arthritis
0.719 0.281 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.718 0.282 0.000
S40-S49 Injuries to the shoulder and upper arm
0.717 0.282 0.000
H35 Other retinal disorders
0.717 0.283 0.000
J37 Chronic laryngitis and laryngotracheitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M45 Ankylosing spondylitis
0.716 0.284 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.716 0.284 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
J33.1 Polypoid sinus degeneration
0.715 0.285 0.000
W18 Other fall on same level
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.285 0.000
F70-F79 Mental retardation
0.714 0.285 0.000
M22.4 Chondromalacia patellae
0.714 0.286 0.000
W17 Other fall from one level to another
0.713 0.287 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.713 0.287 0.000
W15 Fall from cliff
0.713 0.287 0.000
W14 Fall from tree
0.713 0.287 0.000
W12 Fall on and from scaffolding
0.713 0.287 0.000
W11 Fall on and from ladder
0.713 0.287 0.000
W09 Fall involving playground equipment
0.713 0.287 0.000
W08 Fall involving other furniture
0.713 0.287 0.000
W05 Fall involving wheelchair
0.713 0.287 0.000
W04 Fall while being carried or supported by other persons
0.713 0.287 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.713 0.287 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.713 0.287 0.000
W00 Fall on same level involving ice and snow
0.713 0.287 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.713 0.287 0.000
H90 Conductive and sensorineural hearing loss
0.711 0.289 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.710 0.290 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.710 0.290 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.710 0.290 0.000
N46 Male infertility
0.710 0.290 0.000
N44 Torsion of testis
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.709 0.291 0.000
V10-V19 Pedal cyclist injured in transport accident
0.709 0.291 0.000
I46.0 Cardiac arrest with successful resuscitation
0.708 0.291 0.000
W07.9 Unspecified place
0.708 0.292 0.000
N42.9 Disorder of prostate, unspecified
0.708 0.292 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.707 0.293 0.000
N99-N99 Other disorders of the genitourinary system
0.707 0.293 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.706 0.294 0.000
T87 Complications peculiar to reattachment and amputation
0.706 0.294 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.706 0.294 0.000
D63.0 Anaemia in neoplastic disease
0.706 0.294 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.706 0.294 0.000
M00-M03 Infectious arthropathies
0.705 0.294 0.000
N40 Hyperplasia of prostate
0.705 0.295 0.000
D69.6 Thrombocytopenia, unspecified
0.705 0.295 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.705 0.295 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.705 0.295 0.000
W19.8 Other specified place
0.703 0.297 0.000
W19.5 Trade and service area
0.703 0.297 0.000
W19.0 Home
0.703 0.297 0.000
W19.7 Farm
0.703 0.297 0.000
W19.6 Industrial and construction area
0.703 0.297 0.000
W19.1 Residential institution
0.703 0.297 0.000
J20-J22 Other acute lower respiratory infections
0.703 0.297 0.000
N42.2 Atrophy of prostate
0.703 0.297 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.703 0.297 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.703 0.297 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.702 0.298 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.702 0.298 0.000
N20.1 Calculus of ureter
0.701 0.299 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.700 0.300 0.000
M05 Seropositive rheumatoid arthritis
0.699 0.301 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.699 0.301 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.697 0.302 0.000
N48.8 Other specified disorders of penis
0.697 0.303 0.000
N41 Inflammatory diseases of prostate
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.697 0.303 0.000
I48 Atrial fibrillation and flutter
0.697 0.303 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.697 0.303 0.000
I41 Myocarditis in diseases classified elsewhere
0.697 0.303 0.000
I40 Acute myocarditis
0.697 0.303 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.697 0.303 0.000
I37 Pulmonary valve disorders
0.697 0.303 0.000
I32 Pericarditis in diseases classified elsewhere
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.697 0.303 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
I72.0 Aneurysm of carotid artery
0.695 0.304 0.000
S81 Open wound of lower leg
0.695 0.304 0.000
D69.0 Allergic purpura
0.695 0.305 0.000
J31.0 Chronic rhinitis
0.695 0.305 0.000
I30 Acute pericarditis
0.694 0.306 0.000
Y88 Sequelae of surgical and medical care as external cause
0.694 0.306 0.000
M91-M94 Chondropathies
0.694 0.306 0.000
O00 Ectopic pregnancy
0.693 0.307 0.000
F01 Vascular dementia
0.693 0.307 0.000
W13.9 Unspecified place
0.692 0.308 0.000
T79-T79 Certain early complications of trauma
0.691 0.309 0.000
M07 Psoriatic and enteropathic arthropathies
0.690 0.309 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.690 0.309 0.000
N11 Chronic tubulo-interstitial nephritis
0.689 0.311 0.000
N43.3 Hydrocele, unspecified
0.689 0.311 0.000
I44.1 Atrioventricular block, second degree
0.688 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.688 0.312 0.000
Y40.3 Macrolides
0.688 0.312 0.000
H93 Other disorders of ear, not elsewhere classified
0.688 0.312 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.688 0.312 0.000
M47.8 Other spondylosis
0.687 0.313 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.687 0.313 0.000
N05 Unspecified nephritic syndrome
0.686 0.314 0.000
I42 Cardiomyopathy
0.685 0.315 0.000
O23 Infections of genito-urinary tract in pregnancy
0.684 0.315 0.000
M16 Coxarthrosis [arthrosis of hip]
0.684 0.316 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.683 0.317 0.000
M18 Arthrosis of first carpometacarpal joint
0.681 0.319 0.000
S72 Fracture of femur
0.681 0.319 0.000
J80 Adult respiratory distress syndrome
0.680 0.320 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.678 0.322 0.000
N15 Other renal tubulo-interstitial diseases
0.678 0.322 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.678 0.322 0.000
H31 Other disorders of choroid
0.678 0.322 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.678 0.322 0.000
I63 Cerebral infarction
0.678 0.322 0.000
Y59 Other and unspecified vaccines and biological substances
0.677 0.323 0.000
Y58 Bacterial vaccines
0.677 0.323 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.677 0.323 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.677 0.323 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.677 0.323 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
Y48 Anaesthetics and therapeutic gases
0.677 0.323 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.677 0.323 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.677 0.323 0.000
N48.9 Disorder of penis, unspecified
0.677 0.323 0.000
N48.5 Ulcer of penis
0.677 0.323 0.000
N48.3 Priapism
0.677 0.323 0.000
N48.2 Other inflammatory disorders of penis
0.677 0.323 0.000
S09 Other and unspecified injuries of head
0.676 0.324 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.676 0.324 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.675 0.325 0.000
D67 Hereditary factor IX deficiency
0.675 0.325 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.675 0.325 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.675 0.325 0.000
S50-S59 Injuries to the elbow and forearm
0.675 0.325 0.000
I08 Multiple valve diseases
0.674 0.326 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.673 0.327 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.673 0.327 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.673 0.327 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.673 0.327 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.673 0.327 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.673 0.327 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.673 0.327 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.673 0.327 0.000
F40.2 Specific (isolated) phobias
0.673 0.327 0.000
I62 Other nontraumatic intracranial haemorrhage
0.672 0.328 0.000
H10-H13 Disorders of conjunctiva
0.670 0.329 0.000
I44.3 Other and unspecified atrioventricular block
0.669 0.331 0.000
F32 Depressive episode
0.669 0.331 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.669 0.331 0.000
Q60-Q64 Congenital malformations of the urinary system
0.669 0.331 0.000
F99 Mental disorder, not otherwise specified
0.668 0.332 0.000
M48 Other spondylopathies
0.668 0.332 0.000
M65-M68 Disorders of synovium and tendon
0.668 0.332 0.000
I44.6 Other and unspecified fascicular block
0.667 0.333 0.000
I44.5 Left posterior fascicular block
0.667 0.333 0.000
I44.4 Left anterior fascicular block
0.667 0.333 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.667 0.333 0.000
H18 Other disorders of cornea
0.666 0.334 0.000
S06 Intracranial injury
0.666 0.334 0.000
H20 Iridocyclitis
0.666 0.334 0.000
M40-M43 Deforming dorsopathies
0.666 0.334 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.665 0.334 0.000
F02 Dementia in other diseases classified elsewhere
0.665 0.334 0.000
F09 Unspecified organic or symptomatic mental disorder
0.665 0.334 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.665 0.334 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.665 0.335 0.000
N42.3 Dysplasia of prostate
0.664 0.336 0.000
O21 Excessive vomiting in pregnancy
0.664 0.336 0.000
M21 Other acquired deformities of limbs
0.664 0.336 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.663 0.337 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.663 0.337 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.663 0.337 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.663 0.337 0.000
N20.9 Urinary calculus, unspecified
0.662 0.337 0.000
D69.5 Secondary thrombocytopenia
0.662 0.338 0.000
N48.0 Leukoplakia of penis
0.662 0.338 0.000
M11 Other crystal arthropathies
0.661 0.339 0.000
N48.4 Impotence of organic origin
0.661 0.339 0.000
E11 Non-insulin-dependent diabetes mellitus
0.660 0.340 0.000
N19 Unspecified renal failure
0.660 0.340 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.660 0.340 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.659 0.341 0.000
F17.1 Harmful use
0.658 0.342 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.658 0.342 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.657 0.342 0.000
S80.0 Contusion of knee
0.657 0.343 0.000
T88.5 Other complications of anaesthesia
0.657 0.343 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.657 0.343 0.000
N64.5 Other signs and symptoms in breast
0.657 0.343 0.000
H81.1 Benign paroxysmal vertigo
0.656 0.344 0.000
M50-M54 Other dorsopathies
0.656 0.344 0.000
M62 Other disorders of muscle
0.654 0.345 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.653 0.347 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.652 0.347 0.000
M31.3 Wegener's granulomatosis
0.652 0.348 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.652 0.348 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.652 0.348 0.000
H81.0 Meniere's disease
0.651 0.349 0.000
F00 Dementia in Alzheimer's disease
0.651 0.349 0.000
T93 Sequelae of injuries of lower limb
0.650 0.350 0.000
H43 Disorders of vitreous body
0.650 0.350 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.650 0.350 0.000
T75 Effects of other external causes
0.649 0.351 0.000
T74 Maltreatment syndromes
0.649 0.351 0.000
T73 Effects of other deprivation
0.649 0.351 0.000
T70 Effects of air pressure and water pressure
0.649 0.351 0.000
T69 Other effects of reduced temperature
0.649 0.351 0.000
T67 Effects of heat and light
0.649 0.351 0.000
T71 Asphyxiation
0.649 0.351 0.000
T66 Unspecified effects of radiation
0.649 0.351 0.000
M25.3 Other instability of joint
0.649 0.351 0.000
N42.1 Congestion and haemorrhage of prostate
0.648 0.351 0.000
S88 Traumatic amputation of lower leg
0.648 0.352 0.000
S87 Crushing injury of lower leg
0.648 0.352 0.000
S86 Injury of muscle and tendon at lower leg level
0.648 0.352 0.000
S85 Injury of blood vessels at lower leg level
0.648 0.352 0.000
S84 Injury of nerves at lower leg level
0.648 0.352 0.000
M14 Arthropathies in other diseases classified elsewhere
0.648 0.352 0.000
M12 Other specific arthropathies
0.648 0.352 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.648 0.352 0.000
M08 Juvenile arthritis
0.648 0.352 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.648 0.352 0.000
O26.8 Other specified pregnancy-related conditions
0.648 0.352 0.000
M34 Systemic sclerosis
0.647 0.353 0.000
N03 Chronic nephritic syndrome
0.646 0.354 0.000
F41 Other anxiety disorders
0.646 0.354 0.000
N50.0 Atrophy of testis
0.645 0.355 0.000
W06 Fall involving bed
0.645 0.355 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.645 0.355 0.000
M33 Dermatopolymyositis
0.645 0.355 0.000
M32 Systemic lupus erythematosus
0.645 0.355 0.000
M30 Polyarteritis nodosa and related conditions
0.645 0.355 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.644 0.356 0.000
F38 Other mood [affective] disorders
0.644 0.356 0.000
F34 Persistent mood [affective] disorders
0.644 0.356 0.000
F30 Manic episode
0.644 0.356 0.000
F39 Unspecified mood [affective] disorder
0.644 0.356 0.000
H21 Other disorders of iris and ciliary body
0.644 0.356 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.642 0.357 0.000
D58 Other hereditary haemolytic anaemias
0.642 0.358 0.000
Y40.8 Other systemic antibiotics
0.641 0.358 0.000
N13.8 Other obstructive and reflux uropathy
0.640 0.360 0.000
F60 Specific personality disorders
0.640 0.360 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.640 0.360 0.000
I27.2 Other secondary pulmonary hypertension
0.638 0.362 0.000
F05.8 Other delirium
0.637 0.363 0.000
F05.1 Delirium superimposed on dementia
0.637 0.363 0.000
F05.0 Delirium not superimposed on dementia, so described
0.637 0.363 0.000
M15 Polyarthrosis
0.636 0.363 0.000
H55-H59 Other disorders of eye and adnexa
0.636 0.363 0.000
F42 Obsessive-compulsive disorder
0.636 0.364 0.000
H35.4 Peripheral retinal degeneration
0.635 0.365 0.000
D59 Acquired haemolytic anaemia
0.635 0.365 0.000
M25.8 Other specified joint disorders
0.635 0.365 0.000
M13.0 Polyarthritis, unspecified
0.634 0.366 0.000
O85-O92 Complications predominantly related to the puerperium
0.634 0.366 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.634 0.366 0.000
H16 Keratitis
0.633 0.367 0.000
H44 Disorders of globe
0.632 0.368 0.000
E10 Insulin-dependent diabetes mellitus
0.631 0.369 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.631 0.369 0.000
M49 Spondylopathies in diseases classified elsewhere
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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