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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs150097632
log Bayes Factor = 16.4138
Chromosome 21   position 40,688,518  (GRCh37) Explore rs150097632 on Ensembl!
Variant rs150097632 is part of Cluster X0110

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
J40-J47 Chronic lower respiratory diseases
0.997 0.003 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.996 0.004 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.993 0.007 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.990 0.010 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
W00-W19 Falls
0.986 0.014 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.984 0.016 0.000
F10.1 Harmful use
0.982 0.018 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.979 0.021 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.976 0.024 0.000
W19 Unspecified fall
0.969 0.031 0.000
J44 Other chronic obstructive pulmonary disease
0.967 0.033 0.000
Z53.8 Procedure not carried out for other reasons
0.967 0.033 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.964 0.036 0.000
M81 Osteoporosis without pathological fracture
0.957 0.043 0.000
W19.9 Unspecified place
0.956 0.044 0.000
G40-G47 Episodic and paroxysmal disorders
0.947 0.053 0.000
J47 Bronchiectasis
0.947 0.053 0.000
M20-M25 Other joint disorders
0.943 0.057 0.000
Y83.8 Other surgical procedures
0.940 0.060 0.000
M81.9 Osteoporosis, unspecified
0.936 0.064 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.931 0.069 0.000
Chapter IX Diseases of the circulatory system
0.930 0.070 0.000
Chapter VII Diseases of the eye and adnexa
0.929 0.071 0.000
I30-I52 Other forms of heart disease
0.927 0.073 0.000
T81 Complications of procedures, not elsewhere classified
0.927 0.073 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.924 0.076 0.000
H30-H36 Disorders of choroid and retina
0.922 0.078 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.920 0.080 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.919 0.081 0.000
H35 Other retinal disorders
0.915 0.085 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.914 0.086 0.000
S60-S69 Injuries to the wrist and hand
0.909 0.091 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.906 0.094 0.000
M15-M19 Arthrosis
0.905 0.095 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.901 0.099 0.000
Chapter I Certain infectious and parasitic diseases
0.901 0.099 0.000
F10.0 Acute intoxication
0.900 0.100 0.000
L20-L30 Dermatitis and eczema
0.896 0.104 0.000
Y83.3 Surgical operation with formation of external stoma
0.895 0.105 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.894 0.106 0.000
I35 Nonrheumatic aortic valve disorders
0.894 0.106 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.893 0.107 0.000
M84 Disorders of continuity of bone
0.892 0.108 0.000
L60-L75 Disorders of skin appendages
0.888 0.112 0.000
M35 Other systemic involvement of connective tissue
0.882 0.118 0.000
H35.3 Degeneration of macula and posterior pole
0.877 0.123 0.000
G47 Sleep disorders
0.877 0.123 0.000
M16 Coxarthrosis [arthrosis of hip]
0.874 0.126 0.000
I50 Heart failure
0.874 0.126 0.000
J09-J18 Influenza and pneumonia
0.871 0.129 0.000
Y83.6 Removal of other organ (partial) (total)
0.871 0.129 0.000
I31 Other diseases of pericardium
0.869 0.131 0.000
Z42 Follow-up care involving plastic surgery
0.866 0.134 0.000
M65-M68 Disorders of synovium and tendon
0.860 0.140 0.000
M31 Other necrotising vasculopathies
0.859 0.141 0.000
S61 Open wound of wrist and hand
0.855 0.145 0.000
S20-S29 Injuries to the thorax
0.855 0.145 0.000
G90-G99 Other disorders of the nervous system
0.855 0.145 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.854 0.146 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.849 0.151 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.847 0.153 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.847 0.153 0.000
F10.2 Dependence syndrome
0.845 0.155 0.000
Chapter II Neoplasms
0.842 0.158 0.000
F17.1 Harmful use
0.840 0.160 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.840 0.160 0.000
M35.3 Polymyalgia rheumatica
0.839 0.161 0.000
H35.8 Other specified retinal disorders
0.838 0.162 0.000
M45-M49 Spondylopathies
0.837 0.163 0.000
Z53.9 Procedure not carried out, unspecified reason
0.830 0.170 0.000
J20-J22 Other acute lower respiratory infections
0.830 0.170 0.000
J40 Bronchitis, not specified as acute or chronic
0.830 0.170 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.829 0.171 0.000
I05-I09 Chronic rheumatic heart diseases
0.826 0.174 0.000
S40-S49 Injuries to the shoulder and upper arm
0.825 0.175 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.822 0.178 0.000
E70-E90 Metabolic disorders
0.822 0.178 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.822 0.178 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.820 0.180 0.000
I51 Complications and ill-defined descriptions of heart disease
0.820 0.180 0.000
Y40 Systemic antibiotics
0.819 0.181 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.817 0.183 0.000
G35 Multiple sclerosis
0.817 0.183 0.000
Z41 Procedures for purposes other than remedying health state
0.817 0.183 0.000
M16.1 Other primary coxarthrosis
0.816 0.184 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
G40 Epilepsy
0.812 0.188 0.000
M25 Other joint disorders, not elsewhere classified
0.812 0.188 0.000
J00-J06 Acute upper respiratory infections
0.811 0.189 0.000
I35.0 Aortic (valve) stenosis
0.810 0.189 0.000
Z46 Fitting and adjustment of other devices
0.810 0.190 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.809 0.191 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.807 0.193 0.000
Chapter XIV Diseases of the genitourinary system
0.807 0.193 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.806 0.194 0.000
I50.1 Left ventricular failure
0.806 0.194 0.000
Y83.4 Other reconstructive surgery
0.804 0.196 0.000
L27 Dermatitis due to substances taken internally
0.800 0.199 0.000
M31.6 Other giant cell arteritis
0.799 0.201 0.000
W18 Other fall on same level
0.798 0.202 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.796 0.204 0.000
G47.3 Sleep apnoea
0.796 0.204 0.000
I31.3 Pericardial effusion (noninflammatory)
0.795 0.205 0.000
M18 Arthrosis of first carpometacarpal joint
0.794 0.206 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.792 0.208 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.792 0.208 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.791 0.209 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.791 0.209 0.000
J42 Unspecified chronic bronchitis
0.790 0.210 0.000
I35.1 Aortic (valve) insufficiency
0.790 0.210 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.786 0.214 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.784 0.216 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.782 0.218 0.000
W50-W64 Exposure to animate mechanical forces
0.782 0.218 0.000
A30-A49 Other bacterial diseases
0.782 0.218 0.000
M86-M90 Other osteopathies
0.779 0.220 0.000
S70-S79 Injuries to the hip and thigh
0.779 0.221 0.000
F10.4 Withdrawal state with delirium
0.779 0.221 0.000
M65 Synovitis and tenosynovitis
0.777 0.223 0.000
H35.7 Separation of retinal layers
0.773 0.226 0.000
M91-M94 Chondropathies
0.773 0.227 0.000
M05-M14 Inflammatory polyarthropathies
0.772 0.228 0.000
H10-H13 Disorders of conjunctiva
0.769 0.231 0.000
M81.98 Osteoporosis, unspecified (Other)
0.769 0.231 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.768 0.232 0.000
N30-N39 Other diseases of urinary system
0.765 0.235 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.761 0.239 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.760 0.240 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.760 0.240 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.756 0.244 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.755 0.245 0.000
G93 Other disorders of brain
0.755 0.245 0.000
W13 Fall from, out of or through building or structure
0.754 0.246 0.000
Chapter XXII Codes for special purposes
0.753 0.247 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.752 0.247 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.752 0.248 0.000
Z34 Supervision of normal pregnancy
0.749 0.251 0.000
J43 Emphysema
0.748 0.252 0.000
Z54 Convalescence
0.748 0.252 0.000
I08 Multiple valve diseases
0.748 0.252 0.000
J30-J39 Other diseases of upper respiratory tract
0.747 0.253 0.000
V80-V89 Other land transport accidents
0.746 0.254 0.000
T66-T78 Other and unspecified effects of external causes
0.746 0.254 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.745 0.255 0.000
H34 Retinal vascular occlusions
0.745 0.255 0.000
N32 Other disorders of bladder
0.745 0.255 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.745 0.255 0.000
G20-G26 Extrapyramidal and movement disorders
0.743 0.256 0.000
H36 Retinal disorders in diseases classified elsewhere
0.743 0.257 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.741 0.259 0.000
L29 Pruritus
0.741 0.259 0.000
I51.8 Other ill-defined heart diseases
0.741 0.259 0.000
F99-F99 Unspecified mental disorder
0.740 0.260 0.000
Z50 Care involving use of rehabilitation procedures
0.740 0.260 0.000
F80-F89 Disorders of psychological development
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
J45 Asthma
0.737 0.263 0.000
N25-N29 Other disorders of kidney and ureter
0.737 0.263 0.000
F60-F69 Disorders of adult personality and behaviour
0.737 0.263 0.000
S64 Injury of nerves at wrist and hand level
0.736 0.264 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.736 0.264 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.735 0.265 0.000
W19.2 School, other institution and public administrative area
0.734 0.266 0.000
Y83.0 Surgical operation with transplant of whole organ
0.733 0.267 0.000
S61.8 Open wound of other parts of wrist and hand
0.733 0.267 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.732 0.268 0.000
I31.9 Disease of pericardium, unspecified
0.732 0.268 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.731 0.269 0.000
M24 Other specific joint derangements
0.731 0.269 0.000
I35.9 Aortic valve disorder, unspecified
0.730 0.270 0.000
Q50-Q56 Congenital malformations of genital organs
0.730 0.270 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.270 0.000
Q60-Q64 Congenital malformations of the urinary system
0.727 0.273 0.000
Z35 Supervision of high-risk pregnancy
0.726 0.274 0.000
L28 Lichen simplex chronicus and prurigo
0.725 0.274 0.000
C60-C63 Malignant neoplasms of male genital organs
0.723 0.277 0.000
C44 Other malignant neoplasms of skin
0.723 0.277 0.000
M84.0 Malunion of fracture
0.722 0.278 0.000
S61.0 Open wound of finger(s) without damage to nail
0.721 0.279 0.000
G30-G32 Other degenerative diseases of the nervous system
0.720 0.280 0.000
M16.0 Primary coxarthrosis, bilateral
0.720 0.280 0.000
G47.9 Sleep disorder, unspecified
0.720 0.280 0.000
I42 Cardiomyopathy
0.720 0.280 0.000
B95-B98 Bacterial, viral and other infectious agents
0.718 0.282 0.000
Z49 Care involving dialysis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
H35.0 Background retinopathy and retinal vascular changes
0.716 0.284 0.000
X60-X84 Intentional self-harm
0.716 0.284 0.000
M80 Osteoporosis with pathological fracture
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
L72.0 Epidermal cyst
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.284 0.000
F70-F79 Mental retardation
0.715 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.714 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.714 0.286 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.714 0.286 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.714 0.286 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.714 0.286 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.714 0.286 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.714 0.286 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.714 0.286 0.000
F11 Mental and behavioural disorders due to use of opioids
0.714 0.286 0.000
F10.9 Unspecified mental and behavioural disorder
0.712 0.288 0.000
F10.8 Other mental and behavioural disorders
0.712 0.288 0.000
F10.7 Residual and late-onset psychotic disorder
0.712 0.288 0.000
F10.6 Amnesic syndrome
0.712 0.288 0.000
F10.5 Psychotic disorder
0.712 0.288 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.712 0.288 0.000
M50-M54 Other dorsopathies
0.711 0.289 0.000
T51 Toxic effect of alcohol
0.711 0.289 0.000
T87 Complications peculiar to reattachment and amputation
0.710 0.290 0.000
T86 Failure and rejection of transplanted organs and tissues
0.710 0.290 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
J22 Unspecified acute lower respiratory infection
0.709 0.291 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.709 0.291 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.709 0.291 0.000
B35-B49 Mycoses
0.708 0.292 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.708 0.292 0.000
E10-E14 Diabetes mellitus
0.708 0.292 0.000
M85 Other disorders of bone density and structure
0.707 0.293 0.000
M83 Adult osteomalacia
0.707 0.293 0.000
M82 Osteoporosis in diseases classified elsewhere
0.707 0.293 0.000
W17 Other fall from one level to another
0.707 0.293 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.707 0.293 0.000
W15 Fall from cliff
0.707 0.293 0.000
W14 Fall from tree
0.707 0.293 0.000
W12 Fall on and from scaffolding
0.707 0.293 0.000
W11 Fall on and from ladder
0.707 0.293 0.000
W10 Fall on and from stairs and steps
0.707 0.293 0.000
W09 Fall involving playground equipment
0.707 0.293 0.000
W08 Fall involving other furniture
0.707 0.293 0.000
W07 Fall involving chair
0.707 0.293 0.000
W05 Fall involving wheelchair
0.707 0.293 0.000
W04 Fall while being carried or supported by other persons
0.707 0.293 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.707 0.293 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.707 0.293 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.707 0.293 0.000
W00 Fall on same level involving ice and snow
0.707 0.293 0.000
J46 Status asthmaticus
0.706 0.294 0.000
M16.7 Other secondary coxarthrosis
0.706 0.294 0.000
T81.9 Unspecified complication of procedure
0.706 0.294 0.000
Y83.5 Amputation of limb(s)
0.705 0.294 0.000
I49 Other cardiac arrhythmias
0.704 0.296 0.000
M22 Disorders of patella
0.703 0.296 0.000
H55-H59 Other disorders of eye and adnexa
0.703 0.297 0.000
Z22 Carrier of infectious disease
0.703 0.297 0.000
Z44 Fitting and adjustment of external prosthetic device
0.702 0.298 0.000
Z52 Donors of organs and tissues
0.701 0.299 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.701 0.299 0.000
M47 Spondylosis
0.701 0.299 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.700 0.299 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.700 0.300 0.000
Z32 Pregnancy examination and test
0.699 0.301 0.000
S67 Crushing injury of wrist and hand
0.698 0.302 0.000
W06 Fall involving bed
0.698 0.302 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.697 0.303 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.697 0.303 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.696 0.304 0.000
W19.4 Street and highway
0.695 0.305 0.000
W19.8 Other specified place
0.695 0.305 0.000
W19.5 Trade and service area
0.695 0.305 0.000
W19.0 Home
0.695 0.305 0.000
W19.7 Farm
0.695 0.305 0.000
W19.6 Industrial and construction area
0.695 0.305 0.000
W19.3 Sports and athletics area
0.695 0.305 0.000
W19.1 Residential institution
0.695 0.305 0.000
S61.1 Open wound of finger(s) with damage to nail
0.694 0.306 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.693 0.307 0.000
Z43 Attention to artificial openings
0.693 0.307 0.000
I50.9 Heart failure, unspecified
0.692 0.308 0.000
L10-L14 Bullous disorders
0.691 0.309 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.691 0.309 0.000
G44 Other headache syndromes
0.690 0.309 0.000
Y40.0 Penicillins
0.690 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.689 0.311 0.000
J95-J99 Other diseases of the respiratory system
0.689 0.311 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.687 0.313 0.000
M81.8 Other osteoporosis
0.686 0.314 0.000
M81.6 Localised osteoporosis [Lequesne]
0.686 0.314 0.000
M81.5 Idiopathic osteoporosis
0.686 0.314 0.000
M81.4 Drug-induced osteoporosis
0.686 0.314 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.686 0.314 0.000
M81.2 Osteoporosis of disuse
0.686 0.314 0.000
M81.1 Postoophorectomy osteoporosis
0.686 0.314 0.000
M81.0 Postmenopausal osteoporosis
0.686 0.314 0.000
Y52 Agents primarily affecting the cardiovascular system
0.686 0.314 0.000
Z47 Other orthopaedic follow-up care
0.686 0.314 0.000
I50.0 Congestive heart failure
0.686 0.314 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.686 0.314 0.000
S09 Other and unspecified injuries of head
0.686 0.314 0.000
N10-N16 Renal tubulo-interstitial diseases
0.685 0.314 0.000
M25.7 Osteophyte
0.685 0.315 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.685 0.315 0.000
Y43 Primarily systemic agents
0.685 0.315 0.000
L50-L54 Urticaria and erythema
0.684 0.316 0.000
E00-E07 Disorders of thyroid gland
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.682 0.318 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.681 0.319 0.000
H53-H54 Visual disturbances and blindness
0.681 0.319 0.000
I30 Acute pericarditis
0.680 0.319 0.000
I08.0 Disorders of both mitral and aortic valves
0.680 0.320 0.000
M65.3 Trigger finger
0.680 0.320 0.000
M21 Other acquired deformities of limbs
0.679 0.321 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.679 0.321 0.000
G41 Status epilepticus
0.679 0.321 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.679 0.321 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.679 0.321 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.679 0.321 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.679 0.321 0.000
V10-V19 Pedal cyclist injured in transport accident
0.678 0.322 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.678 0.322 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.676 0.324 0.000
M34 Systemic sclerosis
0.676 0.324 0.000
M33 Dermatopolymyositis
0.676 0.324 0.000
M32 Systemic lupus erythematosus
0.676 0.324 0.000
M30 Polyarteritis nodosa and related conditions
0.676 0.324 0.000
E20-E35 Disorders of other endocrine glands
0.676 0.324 0.000
O80-O84 Delivery
0.675 0.325 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.675 0.325 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.674 0.326 0.000
A80-A89 Viral infections of the central nervous system
0.674 0.326 0.000
E87.0 Hyperosmolality and hypernatraemia
0.672 0.328 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.671 0.329 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.671 0.329 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.671 0.329 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.671 0.329 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.671 0.329 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.671 0.329 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.671 0.329 0.000
N32.0 Bladder-neck obstruction
0.670 0.330 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.669 0.331 0.000
S90-S99 Injuries to the ankle and foot
0.668 0.331 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.667 0.332 0.000
I35.8 Other aortic valve disorders
0.667 0.333 0.000
Z46.6 Fitting and adjustment of urinary device
0.667 0.333 0.000
I00-I02 Acute rheumatic fever
0.667 0.333 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.666 0.334 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.666 0.334 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.666 0.334 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.665 0.335 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.665 0.335 0.000
I52 Other heart disorders in diseases classified elsewhere
0.665 0.335 0.000
I48 Atrial fibrillation and flutter
0.665 0.335 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.665 0.335 0.000
I41 Myocarditis in diseases classified elsewhere
0.665 0.335 0.000
I40 Acute myocarditis
0.665 0.335 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.665 0.335 0.000
I37 Pulmonary valve disorders
0.665 0.335 0.000
I36 Nonrheumatic tricuspid valve disorders
0.665 0.335 0.000
I32 Pericarditis in diseases classified elsewhere
0.665 0.335 0.000
G37 Other demyelinating diseases of central nervous system
0.664 0.335 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.664 0.336 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.664 0.336 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.664 0.336 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.664 0.336 0.000
H20 Iridocyclitis
0.664 0.336 0.000
W18.5 Trade and service area
0.663 0.337 0.000
S27 Injury of other and unspecified intrathoracic organs
0.662 0.337 0.000
Y59 Other and unspecified vaccines and biological substances
0.662 0.338 0.000
Y58 Bacterial vaccines
0.662 0.338 0.000
Y57 Other and unspecified drugs and medicaments
0.662 0.338 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.662 0.338 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.662 0.338 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.662 0.338 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
Y48 Anaesthetics and therapeutic gases
0.662 0.338 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.662 0.338 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.662 0.338 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.662 0.338 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.662 0.338 0.000
S50-S59 Injuries to the elbow and forearm
0.661 0.339 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.661 0.339 0.000
H31 Other disorders of choroid
0.661 0.339 0.000
H30 Chorioretinal inflammation
0.661 0.339 0.000
C44.4 Skin of scalp and neck
0.661 0.339 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.660 0.340 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
J11 Influenza, virus not identified
0.659 0.341 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.659 0.341 0.000
L73 Other follicular disorders
0.659 0.341 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.659 0.341 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.658 0.342 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.658 0.342 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.657 0.343 0.000
H35.9 Retinal disorder, unspecified
0.656 0.344 0.000
H35.6 Retinal haemorrhage
0.656 0.344 0.000
H35.5 Hereditary retinal dystrophy
0.656 0.344 0.000
H35.2 Other proliferative retinopathy
0.656 0.344 0.000
H35.1 Retinopathy of prematurity
0.656 0.344 0.000
M46 Other inflammatory spondylopathies
0.655 0.345 0.000
Y83.9 Surgical procedure, unspecified
0.654 0.345 0.000
T63 Toxic effect of contact with venomous animals
0.654 0.346 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.654 0.346 0.000
H35.4 Peripheral retinal degeneration
0.653 0.347 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.653 0.347 0.000
S29 Other and unspecified injuries of thorax
0.652 0.348 0.000
S69 Other and unspecified injuries of wrist and hand
0.651 0.348 0.000
S65 Injury of blood vessels at wrist and hand level
0.651 0.348 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.651 0.349 0.000
G43 Migraine
0.651 0.349 0.000
X59 Exposure to unspecified factor
0.650 0.349 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.650 0.350 0.000
N32.9 Bladder disorder, unspecified
0.650 0.350 0.000
M16.9 Coxarthrosis, unspecified
0.650 0.350 0.000
E40-E46 Malnutrition
0.649 0.351 0.000
M15 Polyarthrosis
0.649 0.351 0.000
J00 Acute nasopharyngitis [common cold]
0.649 0.351 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.648 0.352 0.000
M06 Other rheumatoid arthritis
0.648 0.352 0.000
G95 Other diseases of spinal cord
0.648 0.352 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.647 0.353 0.000
J60-J70 Lung diseases due to external agents
0.647 0.353 0.000
S02 Fracture of skull and facial bones
0.647 0.353 0.000
M40-M43 Deforming dorsopathies
0.646 0.354 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.646 0.354 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.646 0.354 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.354 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.646 0.354 0.000
Q00-Q07 Congenital malformations of the nervous system
0.646 0.354 0.000
B99-B99 Other infectious diseases
0.646 0.354 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.646 0.354 0.000
B65-B83 Helminthiases
0.646 0.354 0.000
B50-B64 Protozoal diseases
0.646 0.354 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.646 0.354 0.000
A75-A79 Rickettsioses
0.646 0.354 0.000
A70-A74 Other diseases caused by chlamydiae
0.646 0.354 0.000
A65-A69 Other spirochaetal diseases
0.646 0.354 0.000
A20-A28 Certain zoonotic bacterial diseases
0.646 0.354 0.000
A15-A19 Tuberculosis
0.646 0.354 0.000
G40.9 Epilepsy, unspecified
0.646 0.354 0.000
N35 Urethral stricture
0.646 0.354 0.000
G91 Hydrocephalus
0.646 0.354 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.645 0.354 0.000
J90-J94 Other diseases of pleura
0.645 0.355 0.000
C15-C26 Malignant neoplasms of digestive organs
0.645 0.355 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.645 0.355 0.000
Y40.8 Other systemic antibiotics
0.643 0.356 0.000
A41 Other septicaemia
0.643 0.357 0.000
Y54.3 Benzothiadiazine derivatives
0.643 0.357 0.000
F29 Unspecified nonorganic psychosis
0.643 0.357 0.000
N00-N08 Glomerular diseases
0.643 0.357 0.000
T92 Sequelae of injuries of upper limb
0.643 0.357 0.000
J18 Pneumonia, organism unspecified
0.643 0.357 0.000
L25 Unspecified contact dermatitis
0.642 0.358 0.000
L24 Irritant contact dermatitis
0.642 0.358 0.000
L23 Allergic contact dermatitis
0.642 0.358 0.000
L21 Seborrhoeic dermatitis
0.642 0.358 0.000
L20 Atopic dermatitis
0.642 0.358 0.000
L26 Exfoliative dermatitis
0.642 0.358 0.000
L22 Diaper [napkin] dermatitis
0.642 0.358 0.000
T88.4 Failed or difficult intubation
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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