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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80289820
log Bayes Factor = 14.63
Chromosome 13   position 36,476,290  (GRCh37) Explore rs80289820 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Z51 Other medical care
0.996 0.004 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.993 0.007 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.988 0.012 0.000
Z51.0 Radiotherapy session
0.985 0.015 0.000
Z51.5 Palliative care
0.980 0.020 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.973 0.027 0.000
G90-G99 Other disorders of the nervous system
0.972 0.028 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.971 0.029 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.971 0.029 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.970 0.030 0.000
Y83.8 Other surgical procedures
0.967 0.033 0.000
H43-H45 Disorders of vitreous body and globe
0.967 0.033 0.000
H30-H36 Disorders of choroid and retina
0.965 0.035 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.962 0.038 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.958 0.042 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.955 0.045 0.000
C34 Malignant neoplasm of bronchus and lung
0.950 0.050 0.000
H43 Disorders of vitreous body
0.950 0.050 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.950 0.050 0.000
G40-G47 Episodic and paroxysmal disorders
0.946 0.054 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.943 0.057 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.932 0.068 0.000
G47 Sleep disorders
0.929 0.071 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.925 0.075 0.000
Chapter V Mental and behavioural disorders
0.923 0.077 0.000
M70-M79 Other soft tissue disorders
0.919 0.081 0.000
G62 Other polyneuropathies
0.918 0.082 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.917 0.083 0.000
W20-W49 Exposure to inanimate mechanical forces
0.916 0.084 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.915 0.085 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.908 0.092 0.000
Z93 Artificial opening status
0.908 0.092 0.000
G93 Other disorders of brain
0.908 0.092 0.000
C79 Secondary malignant neoplasm of other sites
0.907 0.093 0.000
Chapter X Diseases of the respiratory system
0.907 0.093 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.905 0.095 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.902 0.098 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.902 0.098 0.000
G47.3 Sleep apnoea
0.899 0.101 0.000
C34.3 Lower lobe, bronchus or lung
0.899 0.101 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.897 0.103 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.896 0.104 0.000
H43.8 Other disorders of vitreous body
0.894 0.106 0.000
H36 Retinal disorders in diseases classified elsewhere
0.892 0.108 0.000
J40-J47 Chronic lower respiratory diseases
0.887 0.113 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.886 0.114 0.000
M50-M54 Other dorsopathies
0.884 0.116 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.878 0.122 0.000
M75 Shoulder lesions
0.877 0.123 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.872 0.128 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.872 0.128 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.871 0.129 0.000
Y43 Primarily systemic agents
0.867 0.133 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.866 0.134 0.000
D70 Agranulocytosis
0.860 0.140 0.000
C45 Mesothelioma
0.857 0.143 0.000
S80-S89 Injuries to the knee and lower leg
0.856 0.144 0.000
C90.0 Multiple myeloma
0.856 0.144 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.855 0.145 0.000
C34.9 Bronchus or lung, unspecified
0.855 0.145 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.854 0.146 0.000
E10-E14 Diabetes mellitus
0.852 0.148 0.000
C50-C50 Malignant neoplasm of breast
0.851 0.149 0.000
Z88.2 Personal history of allergy to sulphonamides
0.851 0.149 0.000
Z51.3 Blood transfusion without reported diagnosis
0.850 0.149 0.000
G62.9 Polyneuropathy, unspecified
0.850 0.150 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.848 0.151 0.000
J44 Other chronic obstructive pulmonary disease
0.848 0.152 0.000
Z88.6 Personal history of allergy to analgesic agent
0.848 0.152 0.000
J43 Emphysema
0.847 0.153 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.845 0.155 0.000
H43.1 Vitreous haemorrhage
0.843 0.157 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.842 0.158 0.000
T79-T79 Certain early complications of trauma
0.841 0.159 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.841 0.159 0.000
G20-G26 Extrapyramidal and movement disorders
0.840 0.160 0.000
H35 Other retinal disorders
0.840 0.160 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.840 0.160 0.000
H36.0 Diabetic retinopathy
0.839 0.161 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.839 0.161 0.000
Z98 Other postsurgical states
0.838 0.162 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.836 0.164 0.000
H33 Retinal detachments and breaks
0.835 0.165 0.000
S40-S49 Injuries to the shoulder and upper arm
0.833 0.167 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.832 0.168 0.000
Z93.1 Gastrostomy status
0.829 0.170 0.000
Z53.9 Procedure not carried out, unspecified reason
0.827 0.173 0.000
M75.5 Bursitis of shoulder
0.826 0.174 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.825 0.175 0.000
W25 Contact with sharp glass
0.824 0.176 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.824 0.176 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.824 0.176 0.000
G47.9 Sleep disorder, unspecified
0.823 0.177 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.821 0.179 0.000
C85.1 B-cell lymphoma, unspecified
0.821 0.179 0.000
S90-S99 Injuries to the ankle and foot
0.820 0.180 0.000
J43.9 Emphysema, unspecified
0.819 0.181 0.000
Z93.3 Colostomy status
0.816 0.184 0.000
M51 Other intervertebral disk disorders
0.816 0.184 0.000
T66-T78 Other and unspecified effects of external causes
0.815 0.185 0.000
G90 Disorders of autonomic nervous system
0.814 0.186 0.000
Z88.5 Personal history of allergy to narcotic agent
0.812 0.188 0.000
C80 Malignant neoplasm without specification of site
0.809 0.191 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.808 0.192 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.807 0.193 0.000
E10 Insulin-dependent diabetes mellitus
0.807 0.193 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.804 0.196 0.000
J40 Bronchitis, not specified as acute or chronic
0.803 0.197 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.803 0.197 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.799 0.201 0.000
H43.3 Other vitreous opacities
0.799 0.201 0.000
X60-X84 Intentional self-harm
0.798 0.202 0.000
Y83.5 Amputation of limb(s)
0.796 0.204 0.000
M45-M49 Spondylopathies
0.796 0.204 0.000
G93.3 Postviral fatigue syndrome
0.794 0.206 0.000
Y43.3 Other antineoplastic drugs
0.792 0.208 0.000
Z93.2 Ileostomy status
0.791 0.209 0.000
Z98.1 Arthrodesis status
0.790 0.210 0.000
Z41 Procedures for purposes other than remedying health state
0.789 0.211 0.000
G95 Other diseases of spinal cord
0.788 0.211 0.000
D60-D64 Aplastic and other anaemias
0.788 0.212 0.000
H10-H13 Disorders of conjunctiva
0.786 0.214 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.785 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.783 0.217 0.000
H33.0 Retinal detachment with retinal break
0.782 0.218 0.000
T81 Complications of procedures, not elsewhere classified
0.782 0.218 0.000
Z93.0 Tracheostomy status
0.781 0.219 0.000
E10.3 With ophthalmic complications
0.781 0.219 0.000
D00-D09 In situ neoplasms
0.780 0.220 0.000
M51.2 Other specified intervertebral disk displacement
0.778 0.222 0.000
C77.2 Intra-abdominal lymph nodes
0.778 0.222 0.000
Z54 Convalescence
0.772 0.228 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.772 0.228 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.771 0.229 0.000
M75.0 Adhesive capsulitis of shoulder
0.771 0.229 0.000
G30-G32 Other degenerative diseases of the nervous system
0.770 0.230 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.770 0.230 0.000
G62.8 Other specified polyneuropathies
0.769 0.231 0.000
Z46 Fitting and adjustment of other devices
0.768 0.232 0.000
Y84.6 Urinary catheterisation
0.767 0.233 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.767 0.233 0.000
G70-G73 Diseases of myoneural junction and muscle
0.766 0.233 0.000
H50 Other strabismus
0.766 0.234 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.765 0.235 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.765 0.235 0.000
D68 Other coagulation defects
0.764 0.236 0.000
S20-S29 Injuries to the thorax
0.764 0.236 0.000
Z49 Care involving dialysis
0.764 0.236 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.764 0.236 0.000
C77.5 Intrapelvic lymph nodes
0.763 0.237 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.762 0.238 0.000
E40-E46 Malnutrition
0.762 0.238 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.762 0.238 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.761 0.239 0.000
W25.9 Unspecified place
0.758 0.242 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.757 0.243 0.000
X50-X57 Overexertion, travel and privation
0.756 0.244 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.756 0.244 0.000
Z51.1 Chemotherapy session for neoplasm
0.756 0.244 0.000
C45.0 Mesothelioma of pleura
0.755 0.245 0.000
V80-V89 Other land transport accidents
0.754 0.246 0.000
H55-H59 Other disorders of eye and adnexa
0.754 0.246 0.000
M76 Enthesopathies of lower limb, excluding foot
0.754 0.246 0.000
Z51.9 Medical care, unspecified
0.754 0.246 0.000
C81 Hodgkin's disease
0.753 0.247 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.752 0.248 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.751 0.249 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.750 0.250 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.746 0.254 0.000
C50 Malignant neoplasm of breast
0.745 0.255 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.745 0.255 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.744 0.256 0.000
Z89 Acquired absence of limb
0.743 0.257 0.000
T18 Foreign body in alimentary tract
0.740 0.260 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.740 0.260 0.000
G62.0 Drug-induced polyneuropathy
0.739 0.261 0.000
C92 Myeloid leukaemia
0.739 0.261 0.000
C90.2 Plasmacytoma, extramedullary
0.738 0.262 0.000
D37.4 Colon
0.738 0.262 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.738 0.262 0.000
C83.3 Large cell (diffuse)
0.737 0.263 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.737 0.263 0.000
S10-S19 Injuries to the neck
0.736 0.264 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.735 0.265 0.000
Chapter VIII Diseases of the ear and mastoid process
0.734 0.266 0.000
Y83.3 Surgical operation with formation of external stoma
0.731 0.269 0.000
C34.1 Upper lobe, bronchus or lung
0.731 0.269 0.000
D75 Other diseases of blood and blood-forming organs
0.730 0.270 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.729 0.271 0.000
T87 Complications peculiar to reattachment and amputation
0.728 0.272 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.728 0.272 0.000
C50.9 Breast, unspecified
0.727 0.273 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.727 0.273 0.000
Z50 Care involving use of rehabilitation procedures
0.726 0.274 0.000
G60 Hereditary and idiopathic neuropathy
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.724 0.276 0.000
M75.1 Rotator cuff syndrome
0.723 0.277 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.721 0.279 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.721 0.279 0.000
Q80-Q89 Other congenital malformations
0.721 0.279 0.000
F41 Other anxiety disorders
0.719 0.281 0.000
Z52 Donors of organs and tissues
0.718 0.282 0.000
M50 Cervical disk disorders
0.718 0.282 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.285 0.000
Z51.6 Desensitisation to allergens
0.714 0.286 0.000
G93.4 Encephalopathy, unspecified
0.712 0.288 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.712 0.288 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
C95 Leukaemia of unspecified cell type
0.712 0.288 0.000
C94 Other leukaemias of specified cell type
0.712 0.288 0.000
C93 Monocytic leukaemia
0.712 0.288 0.000
C88 Malignant immunoproliferative diseases
0.712 0.288 0.000
C86 Other specified types of T/NK-cell lymphoma
0.712 0.288 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.712 0.288 0.000
Z04 Examination and observation for other reasons
0.710 0.290 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.710 0.290 0.000
Y57 Other and unspecified drugs and medicaments
0.710 0.290 0.000
J00-J06 Acute upper respiratory infections
0.710 0.290 0.000
C09 Malignant neoplasm of tonsil
0.709 0.291 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.709 0.291 0.000
C51-C58 Malignant neoplasms of female genital organs
0.709 0.291 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.708 0.292 0.000
F99-F99 Unspecified mental disorder
0.707 0.293 0.000
C77.8 Lymph nodes of multiple regions
0.707 0.293 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.707 0.293 0.000
M40-M43 Deforming dorsopathies
0.706 0.294 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.706 0.294 0.000
H40-H42 Glaucoma
0.705 0.295 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.705 0.295 0.000
E00-E07 Disorders of thyroid gland
0.704 0.296 0.000
C77.4 Inguinal and lower limb lymph nodes
0.704 0.296 0.000
G93.9 Disorder of brain, unspecified
0.704 0.296 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.703 0.297 0.000
C45.7 Mesothelioma of other sites
0.703 0.297 0.000
G12 Spinal muscular atrophy and related syndromes
0.702 0.298 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.701 0.298 0.000
Y84.8 Other medical procedures
0.700 0.300 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.700 0.300 0.000
Z12 Special screening examination for neoplasms
0.700 0.300 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.699 0.301 0.000
Q00-Q07 Congenital malformations of the nervous system
0.699 0.301 0.000
C45.9 Mesothelioma, unspecified
0.699 0.301 0.000
M80-M85 Disorders of bone density and structure
0.698 0.302 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.697 0.303 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.697 0.303 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.697 0.303 0.000
J60-J70 Lung diseases due to external agents
0.697 0.303 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.697 0.303 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
G92 Toxic encephalopathy
0.697 0.303 0.000
Y83.9 Surgical procedure, unspecified
0.696 0.304 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.696 0.304 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.696 0.304 0.000
C32 Malignant neoplasm of larynx
0.696 0.304 0.000
C31 Malignant neoplasm of accessory sinuses
0.696 0.304 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.696 0.304 0.000
C37 Malignant neoplasm of thymus
0.696 0.304 0.000
C33 Malignant neoplasm of trachea
0.696 0.304 0.000
G93.6 Cerebral oedema
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.696 0.304 0.000
Y58 Bacterial vaccines
0.696 0.304 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.696 0.304 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.696 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.696 0.304 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.696 0.304 0.000
Y48 Anaesthetics and therapeutic gases
0.696 0.304 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.696 0.304 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
Y83.0 Surgical operation with transplant of whole organ
0.696 0.304 0.000
H35.2 Other proliferative retinopathy
0.695 0.305 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.695 0.305 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.695 0.305 0.000
S82 Fracture of lower leg, including ankle
0.694 0.306 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.693 0.307 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.693 0.307 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.692 0.308 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.692 0.308 0.000
H31 Other disorders of choroid
0.692 0.308 0.000
H30 Chorioretinal inflammation
0.692 0.308 0.000
G96 Other disorders of central nervous system
0.692 0.308 0.000
F60-F69 Disorders of adult personality and behaviour
0.691 0.309 0.000
Z93.6 Other artificial openings of urinary tract status
0.690 0.310 0.000
Y52 Agents primarily affecting the cardiovascular system
0.690 0.310 0.000
D55-D59 Haemolytic anaemias
0.689 0.310 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.689 0.311 0.000
M79.8 Other specified soft tissue disorders
0.688 0.312 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.687 0.313 0.000
S50-S59 Injuries to the elbow and forearm
0.687 0.313 0.000
S80 Superficial injury of lower leg
0.687 0.313 0.000
T86 Failure and rejection of transplanted organs and tissues
0.687 0.313 0.000
Z45 Adjustment and management of implanted device
0.687 0.313 0.000
G91 Hydrocephalus
0.686 0.313 0.000
M79.6 Pain in limb
0.686 0.313 0.000
Y44 Agents primarily affecting blood constituents
0.686 0.314 0.000
S90 Superficial injury of ankle and foot
0.685 0.315 0.000
G64 Other disorders of peripheral nervous system
0.685 0.315 0.000
T78 Adverse effects, not elsewhere classified
0.684 0.316 0.000
H50.9 Strabismus, unspecified
0.684 0.316 0.000
Z50.0 Cardiac rehabilitation
0.684 0.316 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.683 0.317 0.000
H49 Paralytic strabismus
0.683 0.317 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.683 0.317 0.000
C34.8 Overlapping lesion of bronchus and lung
0.681 0.319 0.000
C34.2 Middle lobe, bronchus or lung
0.681 0.319 0.000
C34.0 Main bronchus
0.681 0.319 0.000
H43.9 Disorder of vitreous body, unspecified
0.681 0.319 0.000
H43.2 Crystalline deposits in vitreous body
0.681 0.319 0.000
H43.0 Vitreous prolapse
0.681 0.319 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.681 0.319 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.681 0.319 0.000
C85.0 Lymphosarcoma
0.681 0.319 0.000
Y42.7 Androgens and anabolic congeners
0.679 0.321 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.678 0.321 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.678 0.322 0.000
G41 Status epilepticus
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
F30-F39 Mood [affective] disorders
0.677 0.323 0.000
G83 Other paralytic syndromes
0.676 0.323 0.000
M60-M63 Disorders of muscles
0.676 0.324 0.000
M00-M03 Infectious arthropathies
0.676 0.324 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.676 0.324 0.000
F80-F89 Disorders of psychological development
0.675 0.325 0.000
H35.0 Background retinopathy and retinal vascular changes
0.675 0.325 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.675 0.325 0.000
E65-E68 Obesity and other hyperalimentation
0.675 0.325 0.000
D37.5 Rectum
0.673 0.327 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.673 0.327 0.000
G24 Dystonia
0.673 0.327 0.000
J30-J39 Other diseases of upper respiratory tract
0.672 0.328 0.000
G11 Hereditary ataxia
0.671 0.329 0.000
E14 Unspecified diabetes mellitus
0.670 0.330 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
Z97 Presence of other devices
0.669 0.331 0.000
M91-M94 Chondropathies
0.668 0.331 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.668 0.332 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.332 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.668 0.332 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.668 0.332 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
T36 Poisoning by systemic antibiotics
0.668 0.332 0.000
G25 Other extrapyramidal and movement disorders
0.668 0.332 0.000
D46 Myelodysplastic syndromes
0.668 0.332 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.667 0.332 0.000
W49.9 Unspecified place
0.668 0.332 0.000
D68.2 Hereditary deficiency of other clotting factors
0.667 0.333 0.000
M46 Other inflammatory spondylopathies
0.667 0.333 0.000
C79.2 Secondary malignant neoplasm of skin
0.667 0.333 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.667 0.333 0.000
G47.8 Other sleep disorders
0.666 0.334 0.000
G47.4 Narcolepsy and cataplexy
0.666 0.334 0.000
G47.2 Disorders of the sleep-wake schedule
0.666 0.334 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.666 0.334 0.000
S70 Superficial injury of hip and thigh
0.665 0.335 0.000
F00 Dementia in Alzheimer's disease
0.665 0.335 0.000
Q60-Q64 Congenital malformations of the urinary system
0.664 0.336 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.663 0.337 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.663 0.337 0.000
C90.3 Solitary plasmacytoma
0.663 0.337 0.000
C90.1 Plasma cell leukaemia
0.663 0.337 0.000
E46 Unspecified protein-energy malnutrition
0.662 0.338 0.000
Y40 Systemic antibiotics
0.662 0.338 0.000
E20-E35 Disorders of other endocrine glands
0.662 0.338 0.000
H35.9 Retinal disorder, unspecified
0.662 0.338 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.662 0.338 0.000
F70-F79 Mental retardation
0.662 0.338 0.000
Z48 Other surgical follow-up care
0.661 0.338 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.661 0.339 0.000
J84 Other interstitial pulmonary diseases
0.660 0.340 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.660 0.340 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.660 0.340 0.000
C77.0 Lymph nodes of head, face and neck
0.659 0.340 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.659 0.341 0.000
V10-V19 Pedal cyclist injured in transport accident
0.659 0.341 0.000
G61 Inflammatory polyneuropathy
0.658 0.341 0.000
G62.2 Polyneuropathy due to other toxic agents
0.658 0.342 0.000
G62.1 Alcoholic polyneuropathy
0.658 0.342 0.000
W44 Foreign body entering into or through eye or natural orifice
0.658 0.342 0.000
Z99.8 Dependence on other enabling machines and devices
0.658 0.342 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.657 0.343 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.657 0.343 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.657 0.343 0.000
C46 Kaposi's sarcoma
0.657 0.343 0.000
D03 Melanoma in situ
0.657 0.343 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.657 0.343 0.000
W46 Contact with hypodermic needle
0.657 0.343 0.000
W45 Foreign body or object entering through skin
0.657 0.343 0.000
W43 Exposure to vibration
0.657 0.343 0.000
W42 Exposure to noise
0.657 0.343 0.000
W41 Exposure to high-pressure jet
0.657 0.343 0.000
W40 Explosion of other materials
0.657 0.343 0.000
W39 Discharge of firework
0.657 0.343 0.000
W38 Explosion and rupture of other specified pressurised devices
0.657 0.343 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.657 0.343 0.000
W36 Explosion and rupture of gas cylinder
0.657 0.343 0.000
W35 Explosion and rupture of boiler
0.657 0.343 0.000
W34 Discharge from other and unspecified firearms
0.657 0.343 0.000
W33 Rifle, shotgun and larger firearm discharge
0.657 0.343 0.000
W32 Handgun discharge
0.657 0.343 0.000
W31 Contact with other and unspecified machinery
0.657 0.343 0.000
W30 Contact with agricultural machinery
0.657 0.343 0.000
W28 Contact with powered lawn mower
0.657 0.343 0.000
W27 Contact with nonpowered hand tool
0.657 0.343 0.000
W26 Contact with knife, sword or dagger
0.657 0.343 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.657 0.343 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.657 0.343 0.000
W21 Striking against or struck by sports equipment
0.657 0.343 0.000
W20 Struck by thrown, projected or falling object
0.657 0.343 0.000
Y42.5 Other oestrogens and progestogens
0.657 0.343 0.000
Z84 Family history of other conditions
0.656 0.344 0.000
Z81 Family history of mental and behavioural disorders
0.656 0.344 0.000
G40 Epilepsy
0.656 0.344 0.000
H53-H54 Visual disturbances and blindness
0.656 0.344 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.655 0.345 0.000
M54 Dorsalgia
0.655 0.345 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.654 0.346 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.653 0.347 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.652 0.348 0.000
D74 Methaemoglobinaemia
0.651 0.349 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.651 0.349 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.651 0.349 0.000
Z93.9 Artificial opening status, unspecified
0.651 0.349 0.000
Z93.8 Other artificial opening status
0.651 0.349 0.000
Z93.5 Cystostomy status
0.651 0.349 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.651 0.349 0.000
G93.8 Other specified disorders of brain
0.651 0.349 0.000
G93.7 Reye's syndrome
0.651 0.349 0.000
G93.5 Compression of brain
0.651 0.349 0.000
G93.2 Benign intracranial hypertension
0.651 0.349 0.000
G93.0 Cerebral cysts
0.651 0.349 0.000
M79.1 Myalgia
0.650 0.350 0.000
C79.6 Secondary malignant neoplasm of ovary
0.650 0.350 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.650 0.350 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.650 0.350 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.650 0.350 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.648 0.352 0.000
W29 Contact with other powered hand tools and household machinery
0.647 0.352 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.647 0.353 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.647 0.353 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.647 0.353 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.647 0.353 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.647 0.353 0.000
D68.8 Other specified coagulation defects
0.646 0.354 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.645 0.355 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.645 0.355 0.000
T45.5 Anticoagulants
0.645 0.355 0.000
H35.6 Retinal haemorrhage
0.645 0.355 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.644 0.355 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.644 0.356 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.643 0.357 0.000
Q50-Q56 Congenital malformations of genital organs
0.643 0.357 0.000
Q35-Q37 Cleft lip and cleft palate
0.643 0.357 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.643 0.357 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.643 0.357 0.000
S89 Other and unspecified injuries of lower leg
0.643 0.357 0.000
G82 Paraplegia and tetraplegia
0.642 0.358 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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