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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77101722
log Bayes Factor = 14.3457
Chromosome 2   position 126,788,300  (GRCh37) Explore rs77101722 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.999 0.001 0.000
T81 Complications of procedures, not elsewhere classified
0.998 0.002 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
R11 Nausea and vomiting
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.987 0.013 0.000
Y83.8 Other surgical procedures
0.986 0.014 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.979 0.021 0.000
Y83.6 Removal of other organ (partial) (total)
0.976 0.024 0.000
G40-G47 Episodic and paroxysmal disorders
0.959 0.041 0.000
R50-R69 General symptoms and signs
0.959 0.041 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.951 0.049 0.000
B95-B98 Bacterial, viral and other infectious agents
0.948 0.052 0.000
Chapter IX Diseases of the circulatory system
0.948 0.052 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
M50-M54 Other dorsopathies
0.945 0.055 0.000
Chapter II Neoplasms
0.944 0.056 0.000
I30-I52 Other forms of heart disease
0.944 0.056 0.000
H25-H28 Disorders of lens
0.941 0.059 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.941 0.059 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.921 0.079 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.920 0.080 0.000
H26 Other cataract
0.918 0.082 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.917 0.083 0.000
H53-H54 Visual disturbances and blindness
0.914 0.086 0.000
R20 Disturbances of skin sensation
0.912 0.088 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.909 0.091 0.000
M54 Dorsalgia
0.906 0.094 0.000
G43 Migraine
0.902 0.098 0.000
G90-G99 Other disorders of the nervous system
0.897 0.103 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.896 0.104 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.896 0.104 0.000
R50 Fever of unknown origin
0.893 0.107 0.000
R18 Ascites
0.886 0.114 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.884 0.116 0.000
M80-M85 Disorders of bone density and structure
0.881 0.119 0.000
A30-A49 Other bacterial diseases
0.880 0.120 0.000
M15-M19 Arthrosis
0.880 0.120 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.878 0.122 0.000
L60-L75 Disorders of skin appendages
0.870 0.130 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.869 0.131 0.000
M54.5 Low back pain
0.868 0.132 0.000
I49 Other cardiac arrhythmias
0.866 0.134 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.865 0.135 0.000
H43-H45 Disorders of vitreous body and globe
0.865 0.135 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.862 0.138 0.000
S20-S29 Injuries to the thorax
0.862 0.138 0.000
R51 Headache
0.862 0.138 0.000
G40 Epilepsy
0.860 0.140 0.000
R12 Heartburn
0.856 0.144 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.853 0.147 0.000
H53 Visual disturbances
0.852 0.148 0.000
G43.9 Migraine, unspecified
0.851 0.149 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.850 0.149 0.000
S90-S99 Injuries to the ankle and foot
0.850 0.150 0.000
H26.9 Cataract, unspecified
0.850 0.150 0.000
R42 Dizziness and giddiness
0.849 0.151 0.000
Chapter XXII Codes for special purposes
0.848 0.152 0.000
M05-M14 Inflammatory polyarthropathies
0.848 0.152 0.000
R50.9 Fever, unspecified
0.846 0.154 0.000
R20.2 Paraesthesia of skin
0.845 0.155 0.000
R15 Faecal incontinence
0.838 0.162 0.000
M16 Coxarthrosis [arthrosis of hip]
0.834 0.166 0.000
M54.56 Low back pain (Lumbar region)
0.834 0.166 0.000
I60-I69 Cerebrovascular diseases
0.829 0.171 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.827 0.173 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.827 0.173 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.826 0.174 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.825 0.175 0.000
Y83.9 Surgical procedure, unspecified
0.824 0.176 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
Chapter VIII Diseases of the ear and mastoid process
0.818 0.182 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.815 0.185 0.000
I34 Nonrheumatic mitral valve disorders
0.813 0.187 0.000
S70-S79 Injuries to the hip and thigh
0.812 0.188 0.000
M16.9 Coxarthrosis, unspecified
0.812 0.188 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.811 0.189 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.811 0.189 0.000
S40-S49 Injuries to the shoulder and upper arm
0.808 0.192 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.806 0.194 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.805 0.195 0.000
H26.4 After-cataract
0.802 0.198 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.801 0.198 0.000
Y83.0 Surgical operation with transplant of whole organ
0.801 0.199 0.000
M20-M25 Other joint disorders
0.799 0.201 0.000
Q21 Congenital malformations of cardiac septa
0.793 0.207 0.000
I47 Paroxysmal tachycardia
0.793 0.207 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.793 0.207 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.791 0.208 0.000
R47-R49 Symptoms and signs involving speech and voice
0.791 0.209 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.790 0.210 0.000
W20-W49 Exposure to inanimate mechanical forces
0.789 0.211 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.788 0.212 0.000
D69 Purpura and other haemorrhagic conditions
0.782 0.218 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.782 0.218 0.000
R16.1 Splenomegaly, not elsewhere classified
0.780 0.220 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.780 0.220 0.000
H26.8 Other specified cataract
0.779 0.221 0.000
M40-M43 Deforming dorsopathies
0.777 0.222 0.000
H43 Disorders of vitreous body
0.777 0.223 0.000
R52 Pain, not elsewhere classified
0.775 0.225 0.000
A49 Bacterial infection of unspecified site
0.774 0.226 0.000
G93 Other disorders of brain
0.770 0.229 0.000
M54.57 Low back pain (Lumbosacral region)
0.769 0.230 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.767 0.233 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.766 0.234 0.000
D60-D64 Aplastic and other anaemias
0.765 0.235 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.765 0.235 0.000
G40.9 Epilepsy, unspecified
0.764 0.236 0.000
I05-I09 Chronic rheumatic heart diseases
0.760 0.239 0.000
R40 Somnolence, stupor and coma
0.760 0.240 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.758 0.242 0.000
L72.0 Epidermal cyst
0.757 0.243 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.757 0.243 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.756 0.244 0.000
M81 Osteoporosis without pathological fracture
0.755 0.245 0.000
B25-B34 Other viral diseases
0.753 0.247 0.000
I44 Atrioventricular and left bundle-branch block
0.750 0.250 0.000
R54 Senility
0.749 0.251 0.000
M54.9 Dorsalgia, unspecified
0.749 0.251 0.000
Q23 Congenital malformations of aortic and mitral valves
0.746 0.254 0.000
M86-M90 Other osteopathies
0.746 0.254 0.000
R63 Symptoms and signs concerning food and fluid intake
0.745 0.255 0.000
G30-G32 Other degenerative diseases of the nervous system
0.744 0.256 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.744 0.256 0.000
S80-S89 Injuries to the knee and lower leg
0.743 0.257 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.743 0.257 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.742 0.258 0.000
I50 Heart failure
0.742 0.258 0.000
T79-T79 Certain early complications of trauma
0.741 0.259 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.739 0.261 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.739 0.261 0.000
I35 Nonrheumatic aortic valve disorders
0.738 0.262 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.737 0.263 0.000
H55-H59 Other disorders of eye and adnexa
0.735 0.264 0.000
B35-B49 Mycoses
0.735 0.265 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.735 0.265 0.000
I46 Cardiac arrest
0.734 0.266 0.000
I42 Cardiomyopathy
0.733 0.267 0.000
Q21.1 Atrial septal defect
0.732 0.268 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
H53.2 Diplopia
0.732 0.268 0.000
H53.9 Visual disturbance, unspecified
0.731 0.269 0.000
V10-V19 Pedal cyclist injured in transport accident
0.730 0.270 0.000
I34.0 Mitral (valve) insufficiency
0.729 0.271 0.000
I38 Endocarditis, valve unspecified
0.729 0.271 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.729 0.271 0.000
I49.3 Ventricular premature depolarisation
0.728 0.272 0.000
T66-T78 Other and unspecified effects of external causes
0.728 0.272 0.000
Q60-Q64 Congenital malformations of the urinary system
0.728 0.272 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
M53 Other dorsopathies, not elsewhere classified
0.724 0.276 0.000
Y84.6 Urinary catheterisation
0.724 0.276 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.724 0.276 0.000
I51 Complications and ill-defined descriptions of heart disease
0.723 0.277 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.723 0.277 0.000
I31 Other diseases of pericardium
0.723 0.277 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.722 0.278 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.722 0.278 0.000
D69.6 Thrombocytopenia, unspecified
0.721 0.279 0.000
M06 Other rheumatoid arthritis
0.721 0.279 0.000
M70-M79 Other soft tissue disorders
0.721 0.279 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.720 0.280 0.000
M65-M68 Disorders of synovium and tendon
0.720 0.280 0.000
M80 Osteoporosis with pathological fracture
0.718 0.282 0.000
R56 Convulsions, not elsewhere classified
0.718 0.282 0.000
Y84.8 Other medical procedures
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Q50-Q56 Congenital malformations of genital organs
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
Y83.5 Amputation of limb(s)
0.716 0.284 0.000
S60-S69 Injuries to the wrist and hand
0.716 0.284 0.000
T81.9 Unspecified complication of procedure
0.715 0.284 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.715 0.284 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.715 0.284 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.715 0.284 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.284 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
M91-M94 Chondropathies
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
S50-S59 Injuries to the elbow and forearm
0.714 0.286 0.000
C50-C50 Malignant neoplasm of breast
0.713 0.286 0.000
C79 Secondary malignant neoplasm of other sites
0.713 0.287 0.000
M10 Gout
0.713 0.287 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.712 0.288 0.000
H43.3 Other vitreous opacities
0.712 0.288 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.712 0.288 0.000
H10-H13 Disorders of conjunctiva
0.709 0.291 0.000
R59 Enlarged lymph nodes
0.709 0.291 0.000
I49.9 Cardiac arrhythmia, unspecified
0.708 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.707 0.292 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.292 0.000
B65-B83 Helminthiases
0.707 0.292 0.000
B50-B64 Protozoal diseases
0.707 0.292 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.292 0.000
B15-B19 Viral hepatitis
0.707 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.292 0.000
A75-A79 Rickettsioses
0.707 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.292 0.000
A65-A69 Other spirochaetal diseases
0.707 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.292 0.000
A15-A19 Tuberculosis
0.707 0.292 0.000
S20 Superficial injury of thorax
0.707 0.293 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.707 0.293 0.000
R69 Unknown and unspecified causes of morbidity
0.705 0.295 0.000
S92 Fracture of foot, except ankle
0.703 0.297 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.700 0.300 0.000
A41 Other septicaemia
0.700 0.300 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.700 0.300 0.000
I69 Sequelae of cerebrovascular disease
0.699 0.301 0.000
G96 Other disorders of central nervous system
0.698 0.302 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.698 0.302 0.000
W00-W19 Falls
0.698 0.302 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
D00-D09 In situ neoplasms
0.697 0.302 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.697 0.303 0.000
Chapter V Mental and behavioural disorders
0.696 0.304 0.000
I47.1 Supraventricular tachycardia
0.696 0.304 0.000
R60 Oedema, not elsewhere classified
0.695 0.305 0.000
G43.1 Migraine with aura [classical migraine]
0.694 0.306 0.000
M45-M49 Spondylopathies
0.693 0.307 0.000
B07 Viral warts
0.692 0.308 0.000
I33 Acute and subacute endocarditis
0.691 0.309 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.691 0.309 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.690 0.310 0.000
D41.4 Bladder
0.688 0.312 0.000
H54 Blindness and low vision
0.688 0.312 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.688 0.312 0.000
G44 Other headache syndromes
0.688 0.312 0.000
G41 Status epilepticus
0.688 0.312 0.000
R68 Other general symptoms and signs
0.688 0.312 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.688 0.312 0.000
R62 Lack of expected normal physiological development
0.688 0.312 0.000
R57 Shock, not elsewhere classified
0.688 0.312 0.000
R64 Cachexia
0.688 0.312 0.000
R58 Haemorrhage, not elsewhere classified
0.688 0.312 0.000
D10-D36 Benign neoplasms
0.684 0.316 0.000
H46 Optic neuritis
0.684 0.316 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.683 0.317 0.000
D75 Other diseases of blood and blood-forming organs
0.683 0.317 0.000
R23 Other skin changes
0.682 0.318 0.000
M50 Cervical disk disorders
0.681 0.319 0.000
G20-G26 Extrapyramidal and movement disorders
0.680 0.320 0.000
I49.0 Ventricular fibrillation and flutter
0.680 0.320 0.000
I00-I02 Acute rheumatic fever
0.680 0.320 0.000
R61 Hyperhidrosis
0.679 0.321 0.000
L60 Nail disorders
0.679 0.321 0.000
D70 Agranulocytosis
0.679 0.321 0.000
M25 Other joint disorders, not elsewhere classified
0.679 0.321 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.679 0.321 0.000
I49.4 Other and unspecified premature depolarisation
0.678 0.322 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.677 0.323 0.000
L50-L54 Urticaria and erythema
0.677 0.323 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.677 0.323 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.677 0.323 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.677 0.323 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.677 0.323 0.000
I52 Other heart disorders in diseases classified elsewhere
0.677 0.323 0.000
I48 Atrial fibrillation and flutter
0.677 0.323 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.677 0.323 0.000
I41 Myocarditis in diseases classified elsewhere
0.677 0.323 0.000
I40 Acute myocarditis
0.677 0.323 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.677 0.323 0.000
I37 Pulmonary valve disorders
0.677 0.323 0.000
I36 Nonrheumatic tricuspid valve disorders
0.677 0.323 0.000
I32 Pericarditis in diseases classified elsewhere
0.677 0.323 0.000
I30 Acute pericarditis
0.677 0.323 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.675 0.325 0.000
H27 Other disorders of lens
0.675 0.325 0.000
S99 Other and unspecified injuries of ankle and foot
0.675 0.325 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.674 0.325 0.000
Q80-Q89 Other congenital malformations
0.674 0.325 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.674 0.325 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.674 0.325 0.000
Q35-Q37 Cleft lip and cleft palate
0.674 0.325 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.674 0.325 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.674 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.325 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.674 0.326 0.000
M54.4 Lumbago with sciatica
0.673 0.327 0.000
H53.4 Visual field defects
0.671 0.328 0.000
C64-C68 Malignant neoplasms of urinary tract
0.671 0.329 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.670 0.330 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.670 0.330 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.669 0.331 0.000
H80-H83 Diseases of inner ear
0.669 0.331 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.669 0.331 0.000
D46 Myelodysplastic syndromes
0.668 0.332 0.000
Y83.3 Surgical operation with formation of external stoma
0.667 0.332 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.665 0.334 0.000
R40.2 Coma, unspecified
0.664 0.336 0.000
M81.9 Osteoporosis, unspecified
0.664 0.336 0.000
U80 Agent resistant to penicillin and related antibiotics
0.661 0.339 0.000
A49.8 Other bacterial infections of unspecified site
0.661 0.339 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.660 0.340 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.660 0.340 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.660 0.340 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.660 0.340 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.660 0.340 0.000
L10-L14 Bullous disorders
0.660 0.340 0.000
L73 Other follicular disorders
0.659 0.341 0.000
D64 Other anaemias
0.659 0.341 0.000
Y83.4 Other reconstructive surgery
0.659 0.341 0.000
H26.3 Drug-induced cataract
0.658 0.341 0.000
H26.2 Complicated cataract
0.658 0.341 0.000
H26.1 Traumatic cataract
0.658 0.341 0.000
H26.0 Infantile, juvenile and presenile cataract
0.658 0.341 0.000
G91 Hydrocephalus
0.656 0.344 0.000
R20.3 Hyperaesthesia
0.654 0.346 0.000
R20.1 Hypoaesthesia of skin
0.654 0.346 0.000
R20.0 Anaesthesia of skin
0.654 0.346 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.654 0.346 0.000
I67 Other cerebrovascular diseases
0.653 0.347 0.000
R45 Symptoms and signs involving emotional state
0.652 0.348 0.000
R46 Symptoms and signs involving appearance and behaviour
0.652 0.348 0.000
R43 Disturbances of smell and taste
0.652 0.348 0.000
I61 Intracerebral haemorrhage
0.652 0.348 0.000
Q23.1 Congenital insufficiency of aortic valve
0.652 0.348 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.651 0.349 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.650 0.350 0.000
M54.8 Other dorsalgia
0.650 0.350 0.000
M54.6 Pain in thoracic spine
0.650 0.350 0.000
M54.0 Panniculitis affecting regions of neck and back
0.650 0.350 0.000
H40-H42 Glaucoma
0.649 0.351 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.649 0.351 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.648 0.352 0.000
R27 Other lack of coordination
0.647 0.353 0.000
G43.8 Other migraine
0.646 0.353 0.000
G43.3 Complicated migraine
0.646 0.353 0.000
G43.2 Status migrainosus
0.646 0.353 0.000
G43.0 Migraine without aura [common migraine]
0.646 0.353 0.000
G93.8 Other specified disorders of brain
0.646 0.354 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.646 0.354 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.646 0.354 0.000
L20-L30 Dermatitis and eczema
0.646 0.354 0.000
S70 Superficial injury of hip and thigh
0.644 0.355 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.644 0.356 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.643 0.357 0.000
G95 Other diseases of spinal cord
0.643 0.357 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.643 0.357 0.000
G90 Disorders of autonomic nervous system
0.643 0.357 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.643 0.357 0.000
G92 Toxic encephalopathy
0.643 0.357 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.643 0.357 0.000
I50.9 Heart failure, unspecified
0.642 0.358 0.000
S27 Injury of other and unspecified intrathoracic organs
0.642 0.358 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.642 0.358 0.000
H53.0 Amblyopia ex anopsia
0.642 0.358 0.000
M19 Other arthrosis
0.642 0.358 0.000
R17 Unspecified jaundice
0.641 0.358 0.000
I60 Subarachnoid haemorrhage
0.641 0.359 0.000
M54.2 Cervicalgia
0.641 0.359 0.000
R50.8 Other specified fever
0.640 0.359 0.000
R50.2 Drug-induced fever
0.640 0.359 0.000
R50.1 Persistent fever
0.640 0.359 0.000
R50.0 Fever with chills
0.640 0.359 0.000
S42 Fracture of shoulder and upper arm
0.637 0.363 0.000
M24 Other specific joint derangements
0.636 0.364 0.000
D22 Melanocytic naevi
0.636 0.364 0.000
D41.0 Kidney
0.636 0.364 0.000
Y84.0 Cardiac catheterisation
0.636 0.364 0.000
M34 Systemic sclerosis
0.635 0.365 0.000
M51 Other intervertebral disk disorders
0.635 0.365 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.635 0.365 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.634 0.366 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.634 0.366 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.634 0.366 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.634 0.366 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.634 0.366 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.634 0.366 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.634 0.366 0.000
C92 Myeloid leukaemia
0.632 0.368 0.000
M85 Other disorders of bone density and structure
0.632 0.368 0.000
M84 Disorders of continuity of bone
0.632 0.368 0.000
M83 Adult osteomalacia
0.632 0.368 0.000
M82 Osteoporosis in diseases classified elsewhere
0.632 0.368 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.632 0.368 0.000
I42.2 Other hypertrophic cardiomyopathy
0.631 0.369 0.000
I45 Other conduction disorders
0.631 0.369 0.000
A48 Other bacterial diseases, not elsewhere classified
0.631 0.369 0.000
A44 Bartonellosis
0.631 0.369 0.000
A43 Nocardiosis
0.631 0.369 0.000
A42 Actinomycosis
0.631 0.369 0.000
A40 Streptococcal septicaemia
0.631 0.369 0.000
A39 Meningococcal infection
0.631 0.369 0.000
A37 Whooping cough
0.631 0.369 0.000
A36 Diphtheria
0.631 0.369 0.000
A32 Listeriosis
0.631 0.369 0.000
A31 Infection due to other mycobacteria
0.631 0.369 0.000
A30 Leprosy [Hansen's disease]
0.631 0.369 0.000
A46 Erysipelas
0.631 0.369 0.000
A38 Scarlet fever
0.631 0.369 0.000
A35 Other tetanus
0.631 0.369 0.000
A34 Obstetrical tetanus
0.631 0.369 0.000
A33 Tetanus neonatorum
0.631 0.369 0.000
M15 Polyarthrosis
0.631 0.369 0.000
M06.9 Rheumatoid arthritis, unspecified
0.631 0.369 0.000
Q28 Other congenital malformations of circulatory system
0.629 0.371 0.000
Q27 Other congenital malformations of peripheral vascular system
0.629 0.371 0.000
Q26 Congenital malformations of great veins
0.629 0.371 0.000
Q25 Congenital malformations of great arteries
0.629 0.371 0.000
Q24 Other congenital malformations of heart
0.629 0.371 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.629 0.371 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.629 0.371 0.000
S72 Fracture of femur
0.628 0.372 0.000
M54.1 Radiculopathy
0.627 0.373 0.000
I46.9 Cardiac arrest, unspecified
0.627 0.373 0.000
A49.0 Staphylococcal infection, unspecified
0.626 0.374 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.626 0.374 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.625 0.375 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.624 0.375 0.000
C34 Malignant neoplasm of bronchus and lung
0.624 0.376 0.000
M16.1 Other primary coxarthrosis
0.624 0.376 0.000
L75 Apocrine sweat disorders
0.623 0.376 0.000
L74 Eccrine sweat disorders
0.623 0.376 0.000
L71 Rosacea
0.623 0.376 0.000
L70 Acne
0.623 0.376 0.000
L68 Hypertrichosis
0.623 0.376 0.000
L67 Hair colour and hair shaft abnormalities
0.623 0.376 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.623 0.376 0.000
L65 Other nonscarring hair loss
0.623 0.376 0.000
L64 Androgenic alopecia
0.623 0.376 0.000
L63 Alopecia areata
0.623 0.376 0.000
L62 Nail disorders in diseases classified elsewhere
0.623 0.376 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.623 0.377 0.000
Y84.9 Medical procedure, unspecified
0.623 0.377 0.000
Y84.7 Blood-sampling
0.623 0.377 0.000
Y84.5 Insertion of gastric or duodenal sound
0.623 0.377 0.000
Y84.4 Aspiration of fluid
0.623 0.377 0.000
Y84.3 Shock therapy
0.623 0.377 0.000
Y84.1 Kidney dialysis
0.623 0.377 0.000
I49.8 Other specified cardiac arrhythmias
0.622 0.378 0.000
M54.55 Low back pain (Thoracolumbar region)
0.622 0.378 0.000
M54.54 Low back pain-Thoracic
0.622 0.378 0.000
M54.53 Low back pain-Cervicothoracic
0.622 0.378 0.000
M54.52 Low back pain-Cervical
0.622 0.378 0.000
M54.51 Low back pain-Occipit-atl-axl
0.622 0.378 0.000
M54.50 Low back pain (Multiple sites in spine)
0.622 0.378 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.622 0.378 0.000
I49.2 Junctional premature depolarisation
0.621 0.379 0.000
I49.1 Atrial premature depolarisation
0.621 0.379 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.620 0.379 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.620 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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