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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs13216156
log Bayes Factor = 13.8063
Chromosome 6   position 157,390,781  (GRCh37) Explore rs13216156 on Ensembl!
Variant rs13216156 is part of Cluster X0007

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
0.999 0.001 0.000
E87.6 Hypokalaemia
0.998 0.002 0.000
N18 Chronic renal failure
0.997 0.003 0.000
H53-H54 Visual disturbances and blindness
0.996 0.004 0.000
N10-N16 Renal tubulo-interstitial diseases
0.995 0.005 0.000
E20-E35 Disorders of other endocrine glands
0.993 0.007 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.993 0.007 0.000
N13 Obstructive and reflux uropathy
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.982 0.018 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.977 0.023 0.000
W00-W19 Falls
0.976 0.024 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.976 0.024 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.975 0.025 0.000
H40-H42 Glaucoma
0.975 0.025 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.973 0.027 0.000
N18.0 End-stage renal disease
0.972 0.028 0.000
H53 Visual disturbances
0.971 0.029 0.000
H54 Blindness and low vision
0.968 0.032 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.967 0.033 0.000
H53.9 Visual disturbance, unspecified
0.966 0.034 0.000
G12 Spinal muscular atrophy and related syndromes
0.961 0.039 0.000
H20 Iridocyclitis
0.958 0.042 0.000
E16 Other disorders of pancreatic internal secretion
0.958 0.042 0.000
H40 Glaucoma
0.958 0.042 0.000
N17 Acute renal failure
0.957 0.043 0.000
G12.2 Motor neuron disease
0.951 0.049 0.000
Y40 Systemic antibiotics
0.948 0.052 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.948 0.052 0.000
N18.9 Chronic renal failure, unspecified
0.947 0.053 0.000
E16.2 Hypoglycaemia, unspecified
0.941 0.059 0.000
Y54.3 Benzothiadiazine derivatives
0.940 0.060 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.938 0.062 0.000
N18.5 Chronic kidney disease, stage 5
0.934 0.066 0.000
E85 Amyloidosis
0.926 0.074 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.924 0.076 0.000
N17.9 Acute renal failure, unspecified
0.922 0.078 0.000
H43-H45 Disorders of vitreous body and globe
0.918 0.082 0.000
H20.9 Iridocyclitis, unspecified
0.915 0.085 0.000
E21.3 Hyperparathyroidism, unspecified
0.914 0.086 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.909 0.091 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.905 0.095 0.000
Y57 Other and unspecified drugs and medicaments
0.905 0.095 0.000
E21.0 Primary hyperparathyroidism
0.905 0.095 0.000
E87.5 Hyperkalaemia
0.902 0.098 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.901 0.099 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.898 0.102 0.000
N18.8 Other chronic renal failure
0.891 0.109 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.891 0.109 0.000
E27 Other disorders of adrenal gland
0.886 0.114 0.000
H55-H59 Other disorders of eye and adnexa
0.886 0.114 0.000
E86 Volume depletion
0.885 0.115 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.884 0.116 0.000
Y52 Agents primarily affecting the cardiovascular system
0.879 0.121 0.000
N20-N23 Urolithiasis
0.878 0.122 0.000
H44 Disorders of globe
0.877 0.123 0.000
N00-N08 Glomerular diseases
0.876 0.124 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.872 0.128 0.000
Y40.8 Other systemic antibiotics
0.872 0.128 0.000
H21 Other disorders of iris and ciliary body
0.871 0.129 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.871 0.129 0.000
H40.1 Primary open-angle glaucoma
0.866 0.134 0.000
H54.0 Blindness, both eyes
0.865 0.135 0.000
L20-L30 Dermatitis and eczema
0.865 0.135 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.864 0.136 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.860 0.140 0.000
W18 Other fall on same level
0.859 0.141 0.000
H40.9 Glaucoma, unspecified
0.859 0.141 0.000
H54.4 Blindness, one eye
0.859 0.141 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.855 0.145 0.000
N20 Calculus of kidney and ureter
0.855 0.145 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.853 0.147 0.000
H40.5 Glaucoma secondary to other eye disorders
0.853 0.147 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.850 0.150 0.000
G90-G99 Other disorders of the nervous system
0.845 0.155 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.845 0.155 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.844 0.156 0.000
H53.4 Visual field defects
0.843 0.157 0.000
O47 False labour
0.843 0.157 0.000
E87.2 Acidosis
0.840 0.160 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.837 0.163 0.000
E85.4 Organ-limited amyloidosis
0.836 0.164 0.000
G70-G73 Diseases of myoneural junction and muscle
0.835 0.165 0.000
Y00-Y09 Assault
0.835 0.165 0.000
G82 Paraplegia and tetraplegia
0.834 0.166 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.834 0.166 0.000
L28 Lichen simplex chronicus and prurigo
0.832 0.168 0.000
N25-N29 Other disorders of kidney and ureter
0.831 0.169 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.830 0.170 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.830 0.170 0.000
E87.3 Alkalosis
0.827 0.173 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.826 0.174 0.000
N13.4 Hydroureter
0.823 0.177 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.820 0.180 0.000
N20.2 Calculus of kidney with calculus of ureter
0.818 0.182 0.000
E22 Hyperfunction of pituitary gland
0.818 0.182 0.000
H44.2 Degenerative myopia
0.816 0.184 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.816 0.184 0.000
O48 Prolonged pregnancy
0.813 0.187 0.000
W75-W84 Other accidental threats to breathing
0.812 0.188 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.811 0.189 0.000
E27.9 Disorder of adrenal gland, unspecified
0.810 0.190 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.809 0.190 0.000
H20.8 Other iridocyclitis
0.809 0.191 0.000
Chapter V Mental and behavioural disorders
0.807 0.193 0.000
N20.0 Calculus of kidney
0.807 0.193 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.806 0.194 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.806 0.194 0.000
D60-D64 Aplastic and other anaemias
0.805 0.195 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.804 0.196 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.801 0.199 0.000
W05 Fall involving wheelchair
0.799 0.201 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.798 0.202 0.000
V90-V94 Water transport accidents
0.796 0.204 0.000
E84 Cystic fibrosis
0.795 0.205 0.000
E87.7 Fluid overload
0.795 0.205 0.000
Y42.7 Androgens and anabolic congeners
0.794 0.206 0.000
H57 Other disorders of eye and adnexa
0.794 0.206 0.000
N11 Chronic tubulo-interstitial nephritis
0.794 0.206 0.000
V80-V89 Other land transport accidents
0.793 0.207 0.000
N13.3 Other and unspecified hydronephrosis
0.793 0.207 0.000
Y57.5 X-ray contrast media
0.793 0.207 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.793 0.207 0.000
W15 Fall from cliff
0.793 0.207 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.792 0.208 0.000
L28.0 Lichen simplex chronicus
0.791 0.209 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.790 0.210 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.790 0.210 0.000
Y42.5 Other oestrogens and progestogens
0.789 0.211 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.788 0.212 0.000
E23 Hypofunction and other disorders of pituitary gland
0.784 0.216 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.783 0.217 0.000
L29 Pruritus
0.782 0.218 0.000
Y44 Agents primarily affecting blood constituents
0.782 0.218 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.779 0.221 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.778 0.222 0.000
G14 Postpolio syndrome
0.778 0.222 0.000
H54.9 Unspecified visual impairment (binocular)
0.777 0.223 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.774 0.226 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.774 0.226 0.000
W19 Unspecified fall
0.772 0.228 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.771 0.229 0.000
G63.2 Diabetic polyneuropathy
0.771 0.229 0.000
X41.9 Unspecified place
0.769 0.231 0.000
W13 Fall from, out of or through building or structure
0.768 0.232 0.000
V10-V19 Pedal cyclist injured in transport accident
0.767 0.233 0.000
X50-X57 Overexertion, travel and privation
0.767 0.233 0.000
O47.9 False labour, unspecified
0.764 0.236 0.000
O85-O92 Complications predominantly related to the puerperium
0.764 0.236 0.000
G30-G32 Other degenerative diseases of the nervous system
0.764 0.236 0.000
X58 Exposure to other specified factors
0.763 0.237 0.000
Y40.7 Antifungal antibiotics, systemically used
0.761 0.239 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.761 0.239 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.759 0.241 0.000
W08 Fall involving other furniture
0.758 0.242 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.758 0.242 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.758 0.242 0.000
Y85 Sequelae of transport accidents
0.757 0.243 0.000
W17 Other fall from one level to another
0.756 0.243 0.000
E85.3 Secondary systemic amyloidosis
0.756 0.244 0.000
Y71 Cardiovascular devices associated with adverse incidents
0.756 0.244 0.000
E28 Ovarian dysfunction
0.755 0.245 0.000
Y57.8 Other drugs and medicaments
0.754 0.246 0.000
F05.9 Delirium, unspecified
0.752 0.248 0.000
G10 Huntington's disease
0.751 0.248 0.000
H54.7 Unspecified visual loss
0.751 0.249 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.750 0.250 0.000
G82.5 Tetraplegia, unspecified
0.748 0.252 0.000
D63.0 Anaemia in neoplastic disease
0.747 0.253 0.000
V01-V09 Pedestrian injured in transport accident
0.746 0.253 0.000
Y10-Y34 Event of undetermined intent
0.746 0.254 0.000
N02 Recurrent and persistent haematuria
0.745 0.255 0.000
H53.1 Subjective visual disturbances
0.745 0.255 0.000
N13.6 Pyonephrosis
0.745 0.255 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.744 0.256 0.000
L20 Atopic dermatitis
0.744 0.256 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.743 0.257 0.000
E74 Other disorders of carbohydrate metabolism
0.742 0.257 0.000
D64 Other anaemias
0.741 0.259 0.000
L29.9 Pruritus, unspecified
0.740 0.260 0.000
E24 Cushing's syndrome
0.739 0.261 0.000
D80-D89 Certain disorders involving the immune mechanism
0.739 0.261 0.000
E20 Hypoparathyroidism
0.737 0.262 0.000
N60-N64 Disorders of breast
0.736 0.264 0.000
G82.2 Paraplegia, unspecified
0.736 0.264 0.000
H20.0 Acute and subacute iridocyclitis
0.735 0.265 0.000
H40.4 Glaucoma secondary to eye inflammation
0.735 0.265 0.000
Y54.5 Other diuretics
0.735 0.265 0.000
G83 Other paralytic syndromes
0.735 0.265 0.000
N62 Hypertrophy of breast
0.733 0.267 0.000
W18.5 Trade and service area
0.732 0.268 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.731 0.269 0.000
H57.1 Ocular pain
0.731 0.269 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.731 0.269 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.730 0.270 0.000
W50-W64 Exposure to animate mechanical forces
0.729 0.271 0.000
H16 Keratitis
0.728 0.271 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.726 0.274 0.000
V70-V79 Bus occupant injured in transport accident
0.726 0.274 0.000
X10-X19 Contact with heat and hot substances
0.726 0.274 0.000
G71 Primary disorders of muscles
0.726 0.274 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.725 0.275 0.000
H58.8 Visual disturbances in diseases classified elsewhere
0.725 0.275 0.000
H20.1 Chronic iridocyclitis
0.725 0.275 0.000
E34 Other endocrine disorders
0.724 0.276 0.000
N17.0 Acute renal failure with tubular necrosis
0.719 0.281 0.000
W06 Fall involving bed
0.719 0.281 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E87.4 Mixed disorder of acid-base balance
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
Y59 Other and unspecified vaccines and biological substances
0.717 0.283 0.000
Y58 Bacterial vaccines
0.717 0.283 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.717 0.283 0.000
H54.5 Low vision, one eye
0.717 0.283 0.000
N18.1 Chronic kidney disease, stage 1
0.715 0.285 0.000
N15 Other renal tubulo-interstitial diseases
0.715 0.285 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.713 0.287 0.000
Y40.0 Penicillins
0.713 0.287 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.712 0.288 0.000
E32 Diseases of thymus
0.712 0.288 0.000
E31 Polyglandular dysfunction
0.712 0.288 0.000
E30 Disorders of puberty, not elsewhere classified
0.712 0.288 0.000
E25 Adrenogenital disorders
0.712 0.288 0.000
W00 Fall on same level involving ice and snow
0.712 0.288 0.000
E16.1 Other hypoglycaemia
0.711 0.289 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.710 0.290 0.000
Q80-Q89 Other congenital malformations
0.710 0.290 0.000
H40.8 Other glaucoma
0.710 0.290 0.000
H15 Disorders of sclera
0.708 0.292 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.708 0.292 0.000
W03.9 Unspecified place
0.707 0.293 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.705 0.295 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.705 0.295 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.705 0.295 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.705 0.295 0.000
N26 Unspecified contracted kidney
0.704 0.296 0.000
Y40.5 Aminoglycosides
0.704 0.296 0.000
H54.6 Unqualified visual loss, one eye
0.702 0.297 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
Chapter I Certain infectious and parasitic diseases
0.701 0.299 0.000
N02.8 Other
0.701 0.299 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.701 0.299 0.000
Y42.9 Other and unspecified hormone antagonists
0.700 0.300 0.000
Y42.4 Oral contraceptives
0.700 0.300 0.000
Y42.2 Antithyroid drugs
0.700 0.300 0.000
Y42.1 Thyroid hormones and substitutes
0.700 0.300 0.000
N05 Unspecified nephritic syndrome
0.700 0.300 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.700 0.300 0.000
W14 Fall from tree
0.700 0.300 0.000
W12 Fall on and from scaffolding
0.700 0.300 0.000
W09 Fall involving playground equipment
0.700 0.300 0.000
W04 Fall while being carried or supported by other persons
0.700 0.300 0.000
W18.3 Sports and athletics area
0.700 0.300 0.000
E15 Nondiabetic hypoglycaemic coma
0.699 0.300 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.699 0.301 0.000
H42 Glaucoma in diseases classified elsewhere
0.699 0.301 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.699 0.301 0.000
L28.1 Prurigo nodularis
0.699 0.301 0.000
Y54.9 Mineral salts, not elsewhere classified
0.698 0.302 0.000
Y54.8 Agents affecting uric acid metabolism
0.698 0.302 0.000
Y54.7 Agents affecting calcification
0.698 0.302 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.698 0.302 0.000
Y54.4 Loop [high-ceiling] diuretics
0.698 0.302 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.698 0.302 0.000
Y54.0 Mineralocorticoids
0.698 0.302 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.697 0.303 0.000
H53.6 Night blindness
0.696 0.303 0.000
H53.5 Colour vision deficiencies
0.696 0.303 0.000
H53.3 Other disorders of binocular vision
0.696 0.303 0.000
E87.0 Hyperosmolality and hypernatraemia
0.696 0.304 0.000
G30 Alzheimer's disease
0.696 0.304 0.000
N17.8 Other acute renal failure
0.695 0.305 0.000
H47.3 Other disorders of optic disk
0.695 0.305 0.000
H54.3 Unqualified visual loss, both eyes
0.694 0.306 0.000
H54.2 Low vision, both eyes
0.694 0.306 0.000
H54.1 Blindness, one eye, low vision, other eye
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
E40-E46 Malnutrition
0.693 0.307 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.693 0.307 0.000
E21.4 Other specified disorders of parathyroid gland
0.693 0.307 0.000
E21.2 Other hyperparathyroidism
0.693 0.307 0.000
H40.0 Glaucoma suspect
0.693 0.307 0.000
G11 Hereditary ataxia
0.693 0.307 0.000
F01 Vascular dementia
0.692 0.308 0.000
H44.4 Hypotony of eye
0.691 0.309 0.000
B35-B49 Mycoses
0.690 0.310 0.000
N27 Small kidney of unknown cause
0.690 0.310 0.000
E85.9 Amyloidosis, unspecified
0.690 0.310 0.000
O60-O75 Complications of labour and delivery
0.689 0.311 0.000
G12.9 Spinal muscular atrophy, unspecified
0.689 0.311 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.689 0.311 0.000
G12.1 Other inherited spinal muscular atrophy
0.689 0.311 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.689 0.311 0.000
Y46.7 Anti-Parkinsonism drugs
0.689 0.311 0.000
H21.8 Other specified disorders of iris and ciliary body
0.688 0.312 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.688 0.312 0.000
H20.2 Lens-induced iridocyclitis
0.687 0.313 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.687 0.313 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.687 0.313 0.000
E16.4 Abnormal secretion of gastrin
0.687 0.313 0.000
E16.3 Increased secretion of glucagon
0.687 0.313 0.000
H40.6 Glaucoma secondary to drugs
0.687 0.313 0.000
H40.3 Glaucoma secondary to eye trauma
0.687 0.313 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.687 0.313 0.000
N17.2 Acute renal failure with medullary necrosis
0.686 0.314 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.686 0.314 0.000
L25 Unspecified contact dermatitis
0.686 0.314 0.000
H44.1 Other endophthalmitis
0.685 0.315 0.000
X58.9 Unspecified place
0.684 0.316 0.000
D64.9 Anaemia, unspecified
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y40.6 Rifamycins
0.680 0.320 0.000
Y40.4 Tetracyclines
0.680 0.320 0.000
Y40.2 Chloramphenicol group
0.680 0.320 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.679 0.321 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.678 0.322 0.000
X45 Accidental poisoning by and exposure to alcohol
0.678 0.322 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.678 0.322 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.677 0.322 0.000
H17 Corneal scars and opacities
0.677 0.323 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.677 0.323 0.000
E23.2 Diabetes insipidus
0.676 0.324 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.675 0.325 0.000
E26 Hyperaldosteronism
0.675 0.325 0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis
0.673 0.327 0.000
F02 Dementia in other diseases classified elsewhere
0.672 0.328 0.000
Y46.6 Other and unspecified antiepileptics
0.672 0.328 0.000
W05.0 Home
0.671 0.329 0.000
H44.0 Purulent endophthalmitis
0.670 0.330 0.000
B37 Candidiasis
0.670 0.330 0.000
Y07 Other maltreatment syndromes
0.670 0.330 0.000
L40-L45 Papulosquamous disorders
0.669 0.331 0.000
H10-H13 Disorders of conjunctiva
0.669 0.331 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.668 0.332 0.000
W11 Fall on and from ladder
0.667 0.333 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.665 0.334 0.000
Q85 Phakomatoses, not elsewhere classified
0.665 0.335 0.000
W84 Unspecified threat to breathing
0.665 0.335 0.000
X59 Exposure to unspecified factor
0.664 0.336 0.000
E85.8 Other amyloidosis
0.664 0.336 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.664 0.336 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.664 0.336 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.664 0.336 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.663 0.337 0.000
E22.0 Acromegaly and pituitary gigantism
0.663 0.337 0.000
O97 Death from sequelae of direct obstetric causes
0.662 0.338 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.662 0.338 0.000
O95 Obstetric death of unspecified cause
0.662 0.338 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.662 0.338 0.000
F00 Dementia in Alzheimer's disease
0.662 0.338 0.000
W15.8 Other specified place
0.661 0.339 0.000
Y40.3 Macrolides
0.660 0.340 0.000
O46.9 Antepartum haemorrhage, unspecified
0.660 0.340 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.658 0.342 0.000
E80.4 Gilbert's syndrome
0.657 0.343 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.653 0.347 0.000
E83 Disorders of mineral metabolism
0.652 0.348 0.000
Y09 Assault by unspecified means
0.652 0.348 0.000
N18.3 Chronic kidney disease, stage 3
0.652 0.348 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.652 0.348 0.000
O87 Venous complications in the puerperium
0.651 0.349 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.651 0.349 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.650 0.350 0.000
V93 Accident on board watercraft without accident to watercraft, not causing drowning and submersion
0.650 0.350 0.000
G71.0 Muscular dystrophy
0.650 0.350 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.649 0.351 0.000
X48 Accidental poisoning by and exposure to pesticides
0.649 0.351 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.649 0.351 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.649 0.351 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.649 0.351 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.649 0.351 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.649 0.351 0.000
Y57.7 Vitamins, not elsewhere classified
0.649 0.351 0.000
Y57.4 Pharmaceutical excipients
0.649 0.351 0.000
Y57.3 Alcohol deterrents
0.649 0.351 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.649 0.351 0.000
Y57.1 Lipotropic drugs
0.649 0.351 0.000
Y57.0 Appetite depressants [anorectics]
0.649 0.351 0.000
L30 Other dermatitis
0.648 0.351 0.000
E84.9 Cystic fibrosis, unspecified
0.648 0.352 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.648 0.352 0.000
Y71.1 Therapeutic (nonsurgical) and rehabilitative devices
0.647 0.353 0.000
H47.1 Papilloedema, unspecified
0.647 0.353 0.000
L10-L14 Bullous disorders
0.646 0.353 0.000
Y57.9 Drug or medicament, unspecified
0.646 0.354 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.646 0.354 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.645 0.355 0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident
0.644 0.355 0.000
H46 Optic neuritis
0.643 0.356 0.000
Y57.6 Other diagnostic agents
0.643 0.357 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.640 0.360 0.000
M80-M85 Disorders of bone density and structure
0.640 0.360 0.000
N04 Nephrotic syndrome
0.640 0.360 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.639 0.361 0.000
E89.2 Postprocedural hypoparathyroidism
0.638 0.362 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.638 0.362 0.000
N13.8 Other obstructive and reflux uropathy
0.637 0.363 0.000
Y46.2 Hydantoin derivatives
0.636 0.363 0.000
O43 Placental disorders
0.636 0.364 0.000
B37.0 Candidal stomatitis
0.636 0.364 0.000
E27.5 Adrenomedullary hyperfunction
0.635 0.365 0.000
E27.0 Other adrenocortical overactivity
0.635 0.365 0.000
B49 Unspecified mycosis
0.634 0.366 0.000
Y82 Other and unspecified medical devices associated with adverse incidents
0.634 0.366 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.634 0.366 0.000
Y80 Physical medicine devices associated with adverse incidents
0.634 0.366 0.000
Y78 Radiological devices associated with adverse incidents
0.634 0.366 0.000
Y75 Neurological devices associated with adverse incidents
0.634 0.366 0.000
Y74 General hospital and personal-use devices associated with adverse incidents
0.634 0.366 0.000
Y72 Otorhinolaryngological devices associated with adverse incidents
0.634 0.366 0.000
Y70 Anaesthesiology devices associated with adverse incidents
0.634 0.366 0.000
G91 Hydrocephalus
0.633 0.367 0.000
Y89 Sequelae of other external causes
0.632 0.368 0.000
X51 Travel and motion
0.632 0.368 0.000
G30.8 Other Alzheimer's disease
0.632 0.368 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.632 0.368 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.630 0.370 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.630 0.370 0.000
Y52.7 Peripheral vasodilators
0.630 0.370 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.630 0.370 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.629 0.370 0.000
G83.8 Other specified paralytic syndromes
0.629 0.371 0.000
H44.9 Disorder of globe, unspecified
0.629 0.371 0.000
H44.8 Other disorders of globe
0.629 0.371 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.629 0.371 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.629 0.371 0.000
H44.5 Degenerated conditions of globe
0.629 0.371 0.000
H44.3 Other degenerative disorders of globe
0.629 0.371 0.000
O47.0 False labour before 37 completed weeks of gestation
0.628 0.371 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.628 0.372 0.000
N06 Isolated proteinuria with specified morphological lesion
0.628 0.372 0.000
N01 Rapidly progressive nephritic syndrome
0.628 0.372 0.000
N00 Acute nephritic syndrome
0.628 0.372 0.000
G95 Other diseases of spinal cord
0.628 0.372 0.000
E28.2 Polycystic ovarian syndrome
0.627 0.372 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.627 0.373 0.000
G70 Myasthenia gravis and other myoneural disorders
0.627 0.373 0.000
X60-X84 Intentional self-harm
0.626 0.374 0.000
W17.6 Industrial and construction area
0.626 0.374 0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
0.625 0.375 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.624 0.375 0.000
H21.4 Pupillary membranes
0.624 0.375 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.624 0.375 0.000
H21.2 Degeneration of iris and ciliary body
0.624 0.375 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.624 0.376 0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents
0.624 0.376 0.000
G81 Hemiplegia
0.623 0.376 0.000
W01.1 Residential institution
0.623 0.377 0.000
Y77 Ophthalmic devices associated with adverse incidents
0.621 0.379 0.000
V40-V49 Car occupant injured in transport accident
0.620 0.379 0.000
L24 Irritant contact dermatitis
0.620 0.380 0.000
L26 Exfoliative dermatitis
0.620 0.380 0.000
L22 Diaper [napkin] dermatitis
0.620 0.380 0.000
D80 Immunodeficiency with predominantly antibody defects
0.620 0.380 0.000
E27.1 Primary adrenocortical insufficiency
0.620 0.380 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.619 0.381 0.000
W13.9 Unspecified place
0.619 0.381 0.000
L23 Allergic contact dermatitis
0.618 0.381 0.000
O46.8 Other antepartum haemorrhage
0.618 0.382 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.617 0.383 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.616 0.383 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.616 0.383 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.616 0.384 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.616 0.384 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.616 0.384 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.616 0.384 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.616 0.384 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.616 0.384 0.000
Y51.0 Anticholinesterase agents
0.616 0.384 0.000
W18.9 Unspecified place
0.616 0.384 0.000
W18.8 Other specified place
0.616 0.384 0.000
W18.4 Street and highway
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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