TreeWAS – Variant ID: rs112996116

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.998	0.002
Chapter X Diseases of the respiratory system	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.998	0.002
Chapter VII Diseases of the eye and adnexa	0.994	0.006
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.993	0.007
R20 Disturbances of skin sensation	0.992	0.008
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.985	0.015
C43-C44 Melanoma and other malignant neoplasms of skin	0.984	0.016
H40-H42 Glaucoma	0.980	0.020
R20.2 Paraesthesia of skin	0.978	0.022
R50-R69 General symptoms and signs	0.971	0.029
H02 Other disorders of eyelid	0.971	0.029
H40 Glaucoma	0.970	0.030
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.969	0.031
J95-J99 Other diseases of the respiratory system	0.962	0.038
Y42.5 Other oestrogens and progestogens	0.956	0.044
R55 Syncope and collapse	0.954	0.046
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.954	0.046
J90-J94 Other diseases of pleura	0.950	0.050
H40.9 Glaucoma, unspecified	0.949	0.051
H01 Other inflammation of eyelid	0.946	0.054
H02.5 Other disorders affecting eyelid function	0.940	0.060
J98 Other respiratory disorders	0.937	0.063
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.936	0.064
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.935	0.065
R47-R49 Symptoms and signs involving speech and voice	0.931	0.069
C43 Malignant melanoma of skin	0.931	0.069
C44 Other malignant neoplasms of skin	0.925	0.075
H01.0 Blepharitis	0.923	0.077
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.917	0.083
C83 Diffuse non-Hodgkin's lymphoma	0.914	0.086
R23 Other skin changes	0.910	0.090
R49 Voice disturbances	0.909	0.091
J98.1 Pulmonary collapse	0.907	0.093
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.906	0.094
C81 Hodgkin's disease	0.906	0.094
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.906	0.094
J60-J70 Lung diseases due to external agents	0.903	0.097
H40.1 Primary open-angle glaucoma	0.901	0.099
J93 Pneumothorax	0.901	0.099
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.899	0.101
R20.8 Other and unspecified disturbances of skin sensation	0.892	0.108
R49.0 Dysphonia	0.892	0.108
C71 Malignant neoplasm of brain	0.890	0.110
R54 Senility	0.889	0.111
R51 Headache	0.887	0.113
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.886	0.114
H02.1 Ectropion of eyelid	0.880	0.120
Y43 Primarily systemic agents	0.879	0.121
R41 Other symptoms and signs involving cognitive functions and awareness	0.873	0.127
R59 Enlarged lymph nodes	0.871	0.129
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.869	0.131
Y60-Y69 Misadventures to patients during surgical and medical care	0.868	0.132
J93.9 Pneumothorax, unspecified	0.867	0.133
J40-J47 Chronic lower respiratory diseases	0.865	0.135
C44.5 Skin of trunk	0.864	0.136
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.862	0.138
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.851	0.149
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.850	0.150
J44 Other chronic obstructive pulmonary disease	0.849	0.151
Y46 Antiepileptics and anti-Parkinsonism drugs	0.849	0.151
R40 Somnolence, stupor and coma	0.845	0.155
D00-D09 In situ neoplasms	0.844	0.156
C81.9 Hodgkin's disease, unspecified	0.839	0.160
H02.6 Xanthelasma of eyelid	0.839	0.161
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.838	0.162
D37-D48 Neoplasms of uncertain or unknown behaviour	0.834	0.166
X58-X59 Accidental exposure to other and unspecified factors	0.832	0.168
J44.8 Other specified chronic obstructive pulmonary disease	0.827	0.173
H40.8 Other glaucoma	0.823	0.177
H46-H48 Disorders of optic nerve and visual pathways	0.823	0.177
X20-X29 Contact with venomous animals and plants	0.820	0.180
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.818	0.182
J69 Pneumonitis due to solids and liquids	0.811	0.189
Y44 Agents primarily affecting blood constituents	0.810	0.190
H02.2 Lagophthalmos	0.810	0.190
C71.2 Temporal lobe	0.810	0.190
C43.6 Malignant melanoma of upper limb, including shoulder	0.805	0.195
Y45.0 Opioids and related analgesics	0.805	0.195
Q50-Q56 Congenital malformations of genital organs	0.802	0.198
R59.0 Localised enlarged lymph nodes	0.801	0.199
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.797	0.203
V40-V49 Car occupant injured in transport accident	0.793	0.207
C34 Malignant neoplasm of bronchus and lung	0.792	0.208
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.791	0.209
C44.2 Skin of ear and external auricular canal	0.791	0.209
Y51 Drugs primarily affecting the autonomic nervous system	0.790	0.209
H05 Disorders of orbit	0.790	0.210
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.790	0.210
J94 Other pleural conditions	0.786	0.214
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.785	0.215
X60-X84 Intentional self-harm	0.785	0.215
C71.9 Brain, unspecified	0.783	0.217
C43.4 Malignant melanoma of scalp and neck	0.783	0.217
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.779	0.221
R23.8 Other and unspecified skin changes	0.778	0.222
R53 Malaise and fatigue	0.776	0.224
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.775	0.225
R58 Haemorrhage, not elsewhere classified	0.775	0.225
C60-C63 Malignant neoplasms of male genital organs	0.772	0.228
Y43.1 Antineoplastic antimetabolites	0.772	0.228
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.771	0.229
C83.3 Large cell (diffuse)	0.771	0.229
Q76 Congenital malformations of spine and bony thorax	0.768	0.232
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.767	0.232
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.767	0.233
W75-W84 Other accidental threats to breathing	0.767	0.233
R21 Rash and other nonspecific skin eruption	0.766	0.234
W00-W19 Falls	0.765	0.235
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.765	0.235
X50-X57 Overexertion, travel and privation	0.765	0.235
H40.5 Glaucoma secondary to other eye disorders	0.764	0.236
C43.3 Malignant melanoma of other and unspecified parts of face	0.763	0.237
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.762	0.238
R40.2 Coma, unspecified	0.761	0.239
Q80-Q89 Other congenital malformations	0.761	0.239
R87 Abnormal findings in specimens from female genital organs	0.758	0.241
J99 Respiratory disorders in diseases classified elsewhere	0.758	0.242
H02.0 Entropion and trichiasis of eyelid	0.758	0.242
J86 Pyothorax	0.757	0.243
J98.4 Other disorders of lung	0.754	0.246
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.751	0.249
C88 Malignant immunoproliferative diseases	0.750	0.250
C92 Myeloid leukaemia	0.750	0.250
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.749	0.251
Y00-Y09 Assault	0.748	0.252
J91 Pleural effusion in conditions classified elsewhere	0.748	0.252
R23.3 Spontaneous ecchymoses	0.746	0.254
J69.0 Pneumonitis due to food and vomit	0.744	0.256
Q65 Congenital deformities of hip	0.743	0.256
R60 Oedema, not elsewhere classified	0.742	0.258
Y46.4 Iminostilbenes	0.742	0.258
Q38-Q45 Other congenital malformations of the digestive system	0.739	0.261
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.739	0.261
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.738	0.262
J42 Unspecified chronic bronchitis	0.737	0.263
C85.7 Other specified types of non-Hodgkin's lymphoma	0.736	0.264
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.735	0.265
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.735	0.265
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.734	0.266
J98.0 Diseases of bronchus, not elsewhere classified	0.732	0.268
D07 Carcinoma in situ of other and unspecified genital organs	0.730	0.270
C32 Malignant neoplasm of larynx	0.725	0.275
R43 Disturbances of smell and taste	0.724	0.276
C43.7 Malignant melanoma of lower limb, including hip	0.723	0.276
H55-H59 Other disorders of eye and adnexa	0.721	0.279
R64 Cachexia	0.719	0.281
J80-J84 Other respiratory diseases principally affecting the interstitium	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
X85-X99 Assault	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X10-X19 Contact with heat and hot substances	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
Y59 Other and unspecified vaccines and biological substances	0.715	0.285
Y58 Bacterial vaccines	0.715	0.285
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.715	0.285
Y53 Agents primarily affecting the gastro-intestinal system	0.715	0.285
Y50 Central nervous system stimulants, not elsewhere classified	0.715	0.285
Y49 Psychotropic drugs, not elsewhere classified	0.715	0.285
Y48 Anaesthetics and therapeutic gases	0.715	0.285
Y47 Sedatives, hypnotics and antianxiety drugs	0.715	0.285
C44.7 Skin of lower limb, including hip	0.714	0.286
Q60-Q64 Congenital malformations of the urinary system	0.714	0.286
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.713	0.287
C44.6 Skin of upper limb, including shoulder	0.713	0.287
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.712	0.288
C95 Leukaemia of unspecified cell type	0.712	0.288
C94 Other leukaemias of specified cell type	0.712	0.288
C93 Monocytic leukaemia	0.712	0.288
C86 Other specified types of T/NK-cell lymphoma	0.712	0.288
X59 Exposure to unspecified factor	0.712	0.288
R20.3 Hyperaesthesia	0.711	0.289
R20.1 Hypoaesthesia of skin	0.711	0.289
R20.0 Anaesthesia of skin	0.711	0.289
M65-M68 Disorders of synovium and tendon	0.707	0.293
R41.0 Disorientation, unspecified	0.707	0.293
H03 Disorders of eyelid in diseases classified elsewhere	0.706	0.294
C50-C50 Malignant neoplasm of breast	0.705	0.295
C02 Malignant neoplasm of other and unspecified parts of tongue	0.705	0.295
H47 Other disorders of optic [2nd] nerve and visual pathways	0.704	0.296
C62 Malignant neoplasm of testis	0.703	0.297
H42 Glaucoma in diseases classified elsewhere	0.702	0.297
J98.5 Diseases of mediastinum, not elsewhere classified	0.701	0.299
C84 Peripheral and cutaneous T-cell lymphomas	0.700	0.299
M80-M85 Disorders of bone density and structure	0.700	0.300
C44.4 Skin of scalp and neck	0.698	0.302
X40-X49 Accidental poisoning by and exposure to noxious substances	0.697	0.302
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.697	0.303
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.696	0.304
R62 Lack of expected normal physiological development	0.696	0.304
H02.7 Other degenerative disorders of eyelid and periocular area	0.696	0.304
R93 Abnormal findings on diagnostic imaging of other body structures	0.696	0.304
H05.0 Acute inflammation of orbit	0.696	0.304
H40.6 Glaucoma secondary to drugs	0.695	0.304
H40.4 Glaucoma secondary to eye inflammation	0.695	0.304
H40.3 Glaucoma secondary to eye trauma	0.695	0.304
C43.9 Malignant melanoma of skin, unspecified	0.695	0.305
Y42.9 Other and unspecified hormone antagonists	0.695	0.305
Y42.4 Oral contraceptives	0.695	0.305
Y42.2 Antithyroid drugs	0.695	0.305
Y42.1 Thyroid hormones and substitutes	0.695	0.305
Y42.0 Glucocorticoids and synthetic analogs	0.695	0.305
R86 Abnormal findings in specimens from male genital organs	0.694	0.306
W07 Fall involving chair	0.694	0.306
D45 Polycythaemia vera	0.692	0.308
C10 Malignant neoplasm of oropharynx	0.692	0.308
X23 Contact with hornets, wasps and bees	0.691	0.309
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.691	0.309
Q66 Congenital deformities of feet	0.690	0.309
J96 Respiratory failure, not elsewhere classified	0.689	0.310
V10-V19 Pedal cyclist injured in transport accident	0.687	0.313
H02.8 Other specified disorders of eyelid	0.687	0.313
J20-J22 Other acute lower respiratory infections	0.686	0.314
J44.9 Chronic obstructive pulmonary disease, unspecified	0.686	0.314
V80-V89 Other land transport accidents	0.685	0.315
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.684	0.316
Q35-Q37 Cleft lip and cleft palate	0.684	0.316
Q30-Q34 Congenital malformations of the respiratory system	0.684	0.316
Q76.0 Spina bifida occulta	0.684	0.316
D50-D53 Nutritional anaemias	0.684	0.316
Y60.0 During surgical operation	0.683	0.317
R85.5 Abnormal microbiological findings	0.683	0.317
D46 Myelodysplastic syndromes	0.683	0.317
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.682	0.318
R22.1 Localised swelling, mass and lump, neck	0.682	0.318
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.680	0.320
Y43.3 Other antineoplastic drugs	0.680	0.320
R23.2 Flushing	0.679	0.321
R23.4 Changes in skin texture	0.679	0.321
R46 Symptoms and signs involving appearance and behaviour	0.678	0.322
C69 Malignant neoplasm of eye and adnexa	0.678	0.322
C45 Mesothelioma	0.678	0.322
H01.9 Inflammation of eyelid, unspecified	0.678	0.322
H01.1 Non-infectious dermatoses of eyelid	0.678	0.322
R49.8 Other and unspecified voice disturbances	0.678	0.322
J86.9 Pyothorax without fistula	0.676	0.324
D01 Carcinoma in situ of other and unspecified digestive organs	0.676	0.324
Y45.1 Salicylates	0.676	0.324
Y44.2 Anticoagulants	0.676	0.324
V20-V29 Motorcycle rider injured in transport accident	0.676	0.324
W18 Other fall on same level	0.675	0.325
R22.0 Localised swelling, mass and lump, head	0.674	0.326
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.674	0.326
J98.6 Disorders of diaphragm	0.674	0.326
M86-M90 Other osteopathies	0.674	0.326
W50-W64 Exposure to animate mechanical forces	0.673	0.327
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.672	0.328
J98.3 Compensatory emphysema	0.672	0.328
J98.2 Interstitial emphysema	0.672	0.328
R23.1 Pallor	0.671	0.328
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.671	0.329
C70 Malignant neoplasm of meninges	0.671	0.329
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.671	0.329
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.671	0.329
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.670	0.330
J00-J06 Acute upper respiratory infections	0.670	0.330
Y57 Other and unspecified drugs and medicaments	0.669	0.331
C82.0 Small cleaved cell, follicular	0.669	0.331
C34.9 Bronchus or lung, unspecified	0.669	0.331
M05-M14 Inflammatory polyarthropathies	0.668	0.332
C81.1 Nodular sclerosis	0.668	0.332
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.667	0.333
C43.8 Overlapping malignant melanoma of skin	0.667	0.333
C43.2 Malignant melanoma of ear and external auricular canal	0.667	0.333
C43.1 Malignant melanoma of eyelid, including canthus	0.667	0.333
C43.0 Malignant melanoma of lip	0.667	0.333
J85 Abscess of lung and mediastinum	0.667	0.333
R57 Shock, not elsewhere classified	0.665	0.334
C34.1 Upper lobe, bronchus or lung	0.665	0.335
Q82 Other congenital malformations of skin	0.664	0.336
Y88 Sequelae of surgical and medical care as external cause	0.664	0.336
C44.1 Skin of eyelid, including canthus	0.664	0.336
C44.8 Overlapping lesion of skin	0.663	0.337
C71.3 Parietal lobe	0.663	0.337
C49 Malignant neoplasm of other connective and soft tissue	0.663	0.337
M65 Synovitis and tenosynovitis	0.661	0.339
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.661	0.339
C44.9 Malignant neoplasm of skin, unspecified	0.661	0.339
Q51 Congenital malformations of uterus and cervix	0.661	0.339
J93.1 Other spontaneous pneumothorax	0.661	0.339
R40.0 Somnolence	0.661	0.339
X68 Intentional self-poisoning by and exposure to pesticides	0.660	0.340
C44.0 Skin of lip	0.658	0.342
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.657	0.343
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.657	0.343
Y45.8 Other analgesics and antipyretics	0.657	0.343
Y45.5 4-Aminophenol derivatives	0.657	0.343
Y45.4 Antirheumatics	0.657	0.343
Y45.2 Propionic acid derivatives	0.657	0.343
C83.0 Small cell (diffuse)	0.657	0.343
C83.7 Burkitt's tumour	0.655	0.345
C83.6 Undifferentiated (diffuse)	0.655	0.345
C83.5 Lymphoblastic (diffuse)	0.655	0.345
C83.4 Immunoblastic (diffuse)	0.655	0.345
C83.2 Mixed small and large cell (diffuse)	0.655	0.345
C83.1 Small cleaved cell (diffuse)	0.655	0.345
C05 Malignant neoplasm of palate	0.655	0.345
R87.6 Abnormal cytological findings	0.653	0.347
R23.0 Cyanosis	0.652	0.347
R49.2 Hypernasality and hyponasality	0.652	0.348
R49.1 Aphonia	0.652	0.348
R44 Other symptoms and signs involving general sensations and perceptions	0.651	0.349
J98.9 Respiratory disorder, unspecified	0.651	0.349
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.650	0.350
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.650	0.350
C85.0 Lymphosarcoma	0.650	0.350
C81.7 Other Hodgkin's disease	0.650	0.350
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.650	0.350
C81.3 Lymphocytic depletion	0.650	0.350
C81.2 Mixed cellularity	0.650	0.350
C81.0 Lymphocytic predominance	0.650	0.350
R89 Abnormal findings in specimens from other organs, systems and tissues	0.649	0.350
R83 Abnormal findings in cerebrospinal fluid	0.649	0.350
J70 Respiratory conditions due to other external agents	0.648	0.352
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.648	0.352
J67 Hypersensitivity pneumonitis due to organic dust	0.648	0.352
J66 Airway disease due to specific organic dust	0.648	0.352
J63 Pneumoconiosis due to other inorganic dusts	0.648	0.352
J62 Pneumoconiosis due to dust containing silica	0.648	0.352
J65 Pneumoconiosis associated with tuberculosis	0.648	0.352
J64 Unspecified pneumoconiosis	0.648	0.352
J60 Coalworker's pneumoconiosis	0.648	0.352
C64-C68 Malignant neoplasms of urinary tract	0.648	0.352
W07.0 Home	0.646	0.354
J93.0 Spontaneous tension pneumothorax	0.646	0.354
V49 Car occupant injured in other and unspecified transport accidents	0.646	0.354
R22.2 Localised swelling, mass and lump, trunk	0.645	0.355
R41.3 Other amnesia	0.645	0.355
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.644	0.356
C38 Malignant neoplasm of heart, mediastinum and pleura	0.644	0.356
C31 Malignant neoplasm of accessory sinuses	0.644	0.356
C30 Malignant neoplasm of nasal cavity and middle ear	0.644	0.356
C37 Malignant neoplasm of thymus	0.644	0.356
C33 Malignant neoplasm of trachea	0.644	0.356
C51-C58 Malignant neoplasms of female genital organs	0.644	0.356
H10-H13 Disorders of conjunctiva	0.644	0.356
C90 Multiple myeloma and malignant plasma cell neoplasms	0.643	0.357
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.642	0.358
Q65.8 Other congenital deformities of hip	0.642	0.358
Y65 Other misadventures during surgical and medical care	0.642	0.358
M65.9 Synovitis and tenosynovitis, unspecified	0.642	0.358
D09 Carcinoma in situ of other and unspecified sites	0.641	0.359
Y41 Other systemic anti-infectives and antiparasitics	0.640	0.360
R41.2 Retrograde amnesia	0.639	0.361
M60-M63 Disorders of muscles	0.639	0.361
C71.8 Overlapping lesion of brain	0.638	0.362
C71.7 Brain stem	0.638	0.362
C71.6 Cerebellum	0.638	0.362
C71.5 Cerebral ventricle	0.638	0.362
C71.4 Occipital lobe	0.638	0.362
C71.0 Cerebrum, except lobes and ventricles	0.638	0.362
R90 Abnormal findings on diagnostic imaging of central nervous system	0.638	0.362
Q54 Hypospadias	0.637	0.363
Q00-Q07 Congenital malformations of the nervous system	0.636	0.363
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.636	0.364
Y54.3 Benzothiadiazine derivatives	0.635	0.365
J09-J18 Influenza and pneumonia	0.635	0.365
Q78 Other osteochondrodysplasias	0.635	0.365
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.635	0.365
Q75 Other congenital malformations of skull and face bones	0.635	0.365
Q74 Other congenital malformations of limb(s)	0.635	0.365
Q73 Reduction defects of unspecified limb	0.635	0.365
Q72 Reduction defects of lower limb	0.635	0.365
Q71 Reduction defects of upper limb	0.635	0.365
Q70 Syndactyly	0.635	0.365
Q69 Polydactyly	0.635	0.365
Q68 Other congenital musculoskeletal deformities	0.635	0.365
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.635	0.365
R59.1 Generalised enlarged lymph nodes	0.634	0.365
D52 Folate deficiency anaemia	0.634	0.366
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.633	0.366
J98.8 Other specified respiratory disorders	0.633	0.367
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.633	0.367
J94.8 Other specified pleural conditions	0.632	0.368
C34.2 Middle lobe, bronchus or lung	0.631	0.369
C04 Malignant neoplasm of floor of mouth	0.631	0.369
C91 Lymphoid leukaemia	0.630	0.370
Y43.9 Primarily systemic agent, unspecified	0.630	0.370
Y43.8 Other primarily systemic agents, not elsewhere classified	0.630	0.370
Y43.6 Enzymes, not elsewhere classified	0.630	0.370
Y43.5 Acidifying and alkalising agents	0.630	0.370
Y43.4 Immunosuppressive agents	0.630	0.370
Y43.2 Antineoplastic natural products	0.630	0.370
Y43.0 Antiallergic and antiemetic drugs	0.630	0.370
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.628	0.372
C92.1 Chronic myeloid leukaemia	0.628	0.372
R80 Isolated proteinuria	0.627	0.373
H01.8 Other specified inflammation of eyelid	0.626	0.373
R41.1 Anterograde amnesia	0.626	0.374
J90 Pleural effusion, not elsewhere classified	0.625	0.375
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.625	0.375
M80 Osteoporosis with pathological fracture	0.625	0.375
D07.5 Prostate	0.623	0.377
D02 Carcinoma in situ of middle ear and respiratory system	0.622	0.378
Y64 Contaminated medical or biological substances	0.622	0.378
Y63 Failure in dosage during surgical and medical care	0.622	0.378
Y62 Failure of sterile precautions during surgical and medical care	0.622	0.378
Y61 Foreign object accidentally left in body during surgical and medical care	0.622	0.378
Y69 Unspecified misadventure during surgical and medical care	0.622	0.378
Y66 Nonadministration of surgical and medical care	0.622	0.378
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.622	0.378
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.621	0.379
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.620	0.379
R84 Abnormal findings in specimens from respiratory organs and thorax	0.620	0.380
J41 Simple and mucopurulent chronic bronchitis	0.620	0.380
C62.9 Testis, unspecified	0.620	0.380
D03 Melanoma in situ	0.620	0.380
J93.8 Other pneumothorax	0.619	0.381
C13 Malignant neoplasm of hypopharynx	0.618	0.382
C11 Malignant neoplasm of nasopharynx	0.618	0.382
C08 Malignant neoplasm of other and unspecified major salivary glands	0.618	0.382
C06 Malignant neoplasm of other and unspecified parts of mouth	0.618	0.382
C03 Malignant neoplasm of gum	0.618	0.382
C00 Malignant neoplasm of lip	0.618	0.382
C12 Malignant neoplasm of pyriform sinus	0.618	0.382
H52 Disorders of refraction and accommodation	0.617	0.383
J94.2 Haemothorax	0.617	0.383
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.617	0.383
C71.1 Frontal lobe	0.615	0.384
J92 Pleural plaque	0.614	0.386
H53-H54 Visual disturbances and blindness	0.614	0.386
R68 Other general symptoms and signs	0.614	0.386
H47.0 Disorders of optic nerve, not elsewhere classified	0.613	0.387
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.613	0.387
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.613	0.387
C43.5 Malignant melanoma of trunk	0.611	0.389
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.610	0.390
C46 Kaposi's sarcoma	0.610	0.390
H43-H45 Disorders of vitreous body and globe	0.610	0.390
Y91 Evidence of alcohol involvement determined by level of intoxication	0.610	0.390
Y46.8 Antispasticity drugs	0.608	0.391
Y46.7 Anti-Parkinsonism drugs	0.608	0.391
Y46.6 Other and unspecified antiepileptics	0.608	0.391
Y46.5 Valproic acid	0.608	0.391
Y46.3 Deoxybarbiturates	0.608	0.391
Y46.2 Hydantoin derivatives	0.608	0.391
Y46.1 Oxazolidinediones	0.608	0.391
Y46.0 Succinimides	0.608	0.391
R59.9 Enlarged lymph nodes, unspecified	0.607	0.393
C34.0 Main bronchus	0.607	0.393
R22.3 Localised swelling, mass and lump, upper limb	0.607	0.393
R40.1 Stupor	0.606	0.394
C07 Malignant neoplasm of parotid gland	0.605	0.395
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.601	0.399
R60.9 Oedema, unspecified	0.601	0.399
C82.6 Cutaneous follicle centre lymphoma	0.601	0.399
C82.5 Diffuse follicle centre lymphoma	0.601	0.399
C82.4 Follicular lymphoma grade IIIb	0.601	0.399
C82.3 Follicular lymphoma grade IIIa	0.601	0.399
C82.2 Large cell, follicular	0.601	0.399
C82.1 Mixed small cleaved and large cell, follicular	0.601	0.399
C01 Malignant neoplasm of base of tongue	0.601	0.399
W84 Unspecified threat to breathing	0.600	0.400
D52.9 Folate deficiency anaemia, unspecified	0.599	0.401
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.598	0.402
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.598	0.402
D04 Carcinoma in situ of skin	0.597	0.402
X58 Exposure to other specified factors	0.596	0.403
Y42.7 Androgens and anabolic congeners	0.596	0.404
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.595	0.405
C32.1 Supraglottis	0.593	0.407
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.592	0.408
J03 Acute tonsillitis	0.591	0.408
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.590	0.410
D41.4 Bladder	0.589	0.411
C60 Malignant neoplasm of penis	0.588	0.412
X29 Contact with unspecified venomous animal or plant	0.588	0.412
X28 Contact with other specified venomous plants	0.588	0.412
X27 Contact with other specified venomous animals	0.588	0.412
X26 Contact with venomous marine animals and plants	0.588	0.412
X25 Contact with other specified venomous arthropods	0.588	0.412
X24 Contact with centipedes and venomous millipedes (tropical)	0.588	0.412
X22 Contact with scorpions	0.588	0.412
X21 Contact with venomous spiders	0.588	0.412
X20 Contact with venomous snakes and lizards	0.588	0.412
X59.2 School, other institution and public administrative area	0.588	0.412
J99.8 Respiratory disorders in other diseases classified elsewhere	0.588	0.412
Y40 Systemic antibiotics	0.587	0.413
Y54.9 Mineral salts, not elsewhere classified	0.587	0.413
Y54.8 Agents affecting uric acid metabolism	0.587	0.413
Y54.7 Agents affecting calcification	0.587	0.413

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations