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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78236847
log Bayes Factor = 19.6533
Chromosome 15   position 33,294,717  (GRCh37) Explore rs78236847 on Ensembl!
Variant rs78236847 is part of Cluster X0091

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
G56 Mononeuropathies of upper limb
0.998 0.002 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
G56.0 Carpal tunnel syndrome
0.993 0.007 0.000
J09-J18 Influenza and pneumonia
0.991 0.009 0.000
M25 Other joint disorders, not elsewhere classified
0.988 0.012 0.000
J18 Pneumonia, organism unspecified
0.985 0.015 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.985 0.015 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.983 0.017 0.000
J95-J99 Other diseases of the respiratory system
0.980 0.020 0.000
J18.1 Lobar pneumonia, unspecified
0.980 0.020 0.000
Y43 Primarily systemic agents
0.974 0.026 0.000
D69 Purpura and other haemorrhagic conditions
0.971 0.029 0.000
J98 Other respiratory disorders
0.968 0.032 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.967 0.033 0.000
C50-C50 Malignant neoplasm of breast
0.967 0.033 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.966 0.034 0.000
G90-G99 Other disorders of the nervous system
0.965 0.035 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.963 0.037 0.000
D69.6 Thrombocytopenia, unspecified
0.961 0.039 0.000
M25.5 Pain in joint
0.960 0.040 0.000
V10-V19 Pedal cyclist injured in transport accident
0.960 0.040 0.000
J98.1 Pulmonary collapse
0.959 0.041 0.000
G50 Disorders of trigeminal nerve
0.958 0.042 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.958 0.042 0.000
Y43.3 Other antineoplastic drugs
0.957 0.043 0.000
E70-E90 Metabolic disorders
0.955 0.045 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.954 0.046 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.951 0.049 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.950 0.050 0.000
E87.6 Hypokalaemia
0.947 0.053 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.946 0.054 0.000
M20 Acquired deformities of fingers and toes
0.944 0.056 0.000
C50 Malignant neoplasm of breast
0.944 0.056 0.000
M20.2 Hallux rigidus
0.940 0.060 0.000
G93 Other disorders of brain
0.937 0.063 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.934 0.066 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.933 0.067 0.000
F60-F69 Disorders of adult personality and behaviour
0.932 0.068 0.000
G50.0 Trigeminal neuralgia
0.929 0.071 0.000
C50.9 Breast, unspecified
0.928 0.072 0.000
Chapter I Certain infectious and parasitic diseases
0.926 0.074 0.000
S20-S29 Injuries to the thorax
0.926 0.074 0.000
S40-S49 Injuries to the shoulder and upper arm
0.923 0.077 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.923 0.077 0.000
F41 Other anxiety disorders
0.921 0.079 0.000
G56.2 Lesion of ulnar nerve
0.919 0.081 0.000
C50.4 Upper-outer quadrant of breast
0.911 0.089 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.910 0.090 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.905 0.095 0.000
M40-M43 Deforming dorsopathies
0.901 0.099 0.000
Y57 Other and unspecified drugs and medicaments
0.901 0.099 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.893 0.107 0.000
V18.0 Driver injured in nontraffic accident
0.892 0.108 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.890 0.110 0.000
F60 Specific personality disorders
0.885 0.115 0.000
D80-D89 Certain disorders involving the immune mechanism
0.881 0.119 0.000
G93.8 Other specified disorders of brain
0.879 0.121 0.000
C51-C58 Malignant neoplasms of female genital organs
0.879 0.121 0.000
T51 Toxic effect of alcohol
0.877 0.123 0.000
Y40 Systemic antibiotics
0.876 0.124 0.000
M91-M94 Chondropathies
0.876 0.124 0.000
F41.2 Mixed anxiety and depressive disorder
0.876 0.124 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.869 0.131 0.000
S10-S19 Injuries to the neck
0.865 0.135 0.000
S42 Fracture of shoulder and upper arm
0.863 0.137 0.000
M23 Internal derangement of knee
0.863 0.137 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.861 0.139 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.861 0.139 0.000
G51 Facial nerve disorders
0.859 0.141 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.858 0.142 0.000
A00-A09 Intestinal infectious diseases
0.857 0.143 0.000
W50-W64 Exposure to animate mechanical forces
0.857 0.143 0.000
J18.9 Pneumonia, unspecified
0.851 0.149 0.000
M21 Other acquired deformities of limbs
0.851 0.149 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.850 0.150 0.000
F17.1 Harmful use
0.850 0.150 0.000
J90-J94 Other diseases of pleura
0.848 0.152 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.843 0.157 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.841 0.159 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.838 0.162 0.000
M25.51 Pain in joint (Shoulder region)
0.835 0.165 0.000
C91 Lymphoid leukaemia
0.834 0.166 0.000
E87.7 Fluid overload
0.833 0.167 0.000
M80-M85 Disorders of bone density and structure
0.833 0.167 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.830 0.170 0.000
F10.0 Acute intoxication
0.827 0.173 0.000
D55-D59 Haemolytic anaemias
0.825 0.175 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.825 0.175 0.000
Y57.9 Drug or medicament, unspecified
0.824 0.176 0.000
M41 Scoliosis
0.820 0.180 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.820 0.180 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.819 0.181 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.818 0.182 0.000
M24 Other specific joint derangements
0.817 0.183 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.813 0.187 0.000
G93.6 Cerebral oedema
0.812 0.188 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.811 0.189 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.810 0.190 0.000
T51.0 Ethanol
0.810 0.190 0.000
F41.9 Anxiety disorder, unspecified
0.807 0.193 0.000
C64-C68 Malignant neoplasms of urinary tract
0.807 0.193 0.000
G91 Hydrocephalus
0.803 0.197 0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.802 0.198 0.000
M35 Other systemic involvement of connective tissue
0.801 0.199 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.800 0.200 0.000
C78.0 Secondary malignant neoplasm of lung
0.800 0.200 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.799 0.201 0.000
M25.52 Pain in joint (Upper arm)
0.799 0.201 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.798 0.202 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.798 0.202 0.000
D86 Sarcoidosis
0.798 0.202 0.000
S90-S99 Injuries to the ankle and foot
0.797 0.202 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.797 0.203 0.000
F60.9 Personality disorder, unspecified
0.797 0.203 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.796 0.203 0.000
M34 Systemic sclerosis
0.796 0.204 0.000
J98.9 Respiratory disorder, unspecified
0.796 0.204 0.000
M70-M79 Other soft tissue disorders
0.796 0.204 0.000
S22.3 Fracture of rib
0.794 0.206 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.794 0.206 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.794 0.206 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.793 0.207 0.000
F10.9 Unspecified mental and behavioural disorder
0.793 0.207 0.000
G20-G26 Extrapyramidal and movement disorders
0.793 0.207 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.791 0.209 0.000
M45-M49 Spondylopathies
0.791 0.209 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.790 0.209 0.000
S27 Injury of other and unspecified intrathoracic organs
0.790 0.210 0.000
M25.7 Osteophyte
0.790 0.210 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.789 0.211 0.000
F60.3 Emotionally unstable personality disorder
0.788 0.212 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.787 0.213 0.000
X50-X57 Overexertion, travel and privation
0.786 0.214 0.000
M25.8 Other specified joint disorders
0.785 0.214 0.000
D72 Other disorders of white blood cells
0.784 0.216 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
G90 Disorders of autonomic nervous system
0.783 0.217 0.000
T59 Toxic effect of other gases, fumes and vapours
0.782 0.218 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.782 0.218 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.781 0.219 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.780 0.220 0.000
E20-E35 Disorders of other endocrine glands
0.779 0.221 0.000
F10.1 Harmful use
0.779 0.221 0.000
C71 Malignant neoplasm of brain
0.778 0.222 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.778 0.222 0.000
A30-A49 Other bacterial diseases
0.777 0.223 0.000
D68 Other coagulation defects
0.777 0.223 0.000
B35-B49 Mycoses
0.775 0.225 0.000
F10.4 Withdrawal state with delirium
0.775 0.225 0.000
M31 Other necrotising vasculopathies
0.774 0.226 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.773 0.227 0.000
D60-D64 Aplastic and other anaemias
0.771 0.229 0.000
M25.9 Joint disorder, unspecified
0.771 0.229 0.000
D69.5 Secondary thrombocytopenia
0.770 0.230 0.000
J17 Pneumonia in diseases classified elsewhere
0.770 0.230 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.770 0.230 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.767 0.233 0.000
J93 Pneumothorax
0.765 0.235 0.000
M33 Dermatopolymyositis
0.764 0.236 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.764 0.236 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.761 0.239 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.761 0.239 0.000
G93.0 Cerebral cysts
0.760 0.240 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.757 0.243 0.000
F80-F89 Disorders of psychological development
0.756 0.244 0.000
E86 Volume depletion
0.755 0.245 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.755 0.245 0.000
S22.30 Fracture of rib (closed)
0.754 0.246 0.000
C15-C26 Malignant neoplasms of digestive organs
0.754 0.246 0.000
G93.2 Benign intracranial hypertension
0.753 0.247 0.000
D66 Hereditary factor VIII deficiency
0.753 0.247 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.752 0.248 0.000
M92 Other juvenile osteochondrosis
0.752 0.248 0.000
S60-S69 Injuries to the wrist and hand
0.752 0.248 0.000
M05-M14 Inflammatory polyarthropathies
0.751 0.249 0.000
G70-G73 Diseases of myoneural junction and muscle
0.751 0.249 0.000
Y40.0 Penicillins
0.751 0.249 0.000
C79.6 Secondary malignant neoplasm of ovary
0.750 0.249 0.000
S36 Injury of intra-abdominal organs
0.750 0.250 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.749 0.250 0.000
M25.0 Haemarthrosis
0.749 0.251 0.000
M86-M90 Other osteopathies
0.749 0.251 0.000
V40-V49 Car occupant injured in transport accident
0.749 0.251 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.748 0.252 0.000
F10.2 Dependence syndrome
0.748 0.252 0.000
M60-M63 Disorders of muscles
0.748 0.252 0.000
T93 Sequelae of injuries of lower limb
0.747 0.252 0.000
D69.0 Allergic purpura
0.746 0.254 0.000
Y40.8 Other systemic antibiotics
0.745 0.255 0.000
M20.0 Deformity of finger(s)
0.744 0.256 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.744 0.256 0.000
E50-E64 Other nutritional deficiencies
0.743 0.257 0.000
E88 Other metabolic disorders
0.743 0.257 0.000
M25.56 Pain in joint (Lower leg)
0.742 0.258 0.000
G56.8 Other mononeuropathies of upper limb
0.742 0.258 0.000
S12 Fracture of neck
0.742 0.258 0.000
M25.3 Other instability of joint
0.741 0.259 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.741 0.259 0.000
S42.3 Fracture of shaft of humerus
0.741 0.259 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.741 0.259 0.000
T66-T78 Other and unspecified effects of external causes
0.741 0.259 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.740 0.260 0.000
M22 Disorders of patella
0.740 0.260 0.000
E40-E46 Malnutrition
0.740 0.260 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.739 0.261 0.000
F43 Reaction to severe stress, and adjustment disorders
0.739 0.261 0.000
T00-T07 Injuries involving multiple body regions
0.738 0.262 0.000
G93.4 Encephalopathy, unspecified
0.737 0.263 0.000
G30-G32 Other degenerative diseases of the nervous system
0.737 0.263 0.000
S40 Superficial injury of shoulder and upper arm
0.736 0.264 0.000
D61 Other aplastic anaemias
0.735 0.264 0.000
A08 Viral and other specified intestinal infections
0.735 0.265 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.732 0.268 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.731 0.269 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.731 0.269 0.000
E85 Amyloidosis
0.731 0.269 0.000
W20-W49 Exposure to inanimate mechanical forces
0.730 0.270 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.730 0.270 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.730 0.270 0.000
J10 Influenza due to identified influenza virus
0.729 0.271 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.729 0.271 0.000
Chapter XXII Codes for special purposes
0.727 0.273 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.727 0.273 0.000
C81 Hodgkin's disease
0.726 0.274 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.726 0.274 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.726 0.274 0.000
C56 Malignant neoplasm of ovary
0.725 0.275 0.000
J14 Pneumonia due to Haemophilus influenzae
0.724 0.275 0.000
M41.9 Scoliosis, unspecified
0.722 0.278 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.721 0.279 0.000
C85.1 B-cell lymphoma, unspecified
0.720 0.280 0.000
T63 Toxic effect of contact with venomous animals
0.717 0.282 0.000
T39.1 4-Aminophenol derivatives
0.717 0.283 0.000
T58 Toxic effect of carbon monoxide
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
G52 Disorders of other cranial nerves
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
F41.1 Generalised anxiety disorder
0.717 0.283 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.716 0.283 0.000
G51.9 Disorder of facial nerve, unspecified
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.716 0.284 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.716 0.284 0.000
G56.4 Causalgia
0.716 0.284 0.000
G56.3 Lesion of radial nerve
0.716 0.284 0.000
G56.1 Other lesions of median nerve
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.285 0.000
Y58 Bacterial vaccines
0.715 0.285 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.715 0.285 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.285 0.000
Y48 Anaesthetics and therapeutic gases
0.715 0.285 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.715 0.285 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.715 0.285 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
F29 Unspecified nonorganic psychosis
0.714 0.286 0.000
D80 Immunodeficiency with predominantly antibody defects
0.713 0.287 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.713 0.287 0.000
D72.8 Other specified disorders of white blood cells
0.713 0.287 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.713 0.287 0.000
Y43.1 Antineoplastic antimetabolites
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.710 0.289 0.000
J12 Viral pneumonia, not elsewhere classified
0.710 0.289 0.000
J09 Influenza due to certain identified influenza virus
0.710 0.289 0.000
D86.0 Sarcoidosis of lung
0.710 0.290 0.000
D61.9 Aplastic anaemia, unspecified
0.710 0.290 0.000
M21.3 Wrist or foot drop (acquired)
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.709 0.290 0.000
M25.2 Flail joint
0.709 0.291 0.000
M25.1 Fistula of joint
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.707 0.293 0.000
J18.8 Other pneumonia, organism unspecified
0.706 0.293 0.000
J18.2 Hypostatic pneumonia, unspecified
0.706 0.293 0.000
T40.2 Other opioids
0.706 0.294 0.000
S42.4 Fracture of lower end of humerus
0.706 0.294 0.000
D67 Hereditary factor IX deficiency
0.706 0.294 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.706 0.294 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.705 0.295 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.705 0.295 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.705 0.295 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.705 0.295 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.705 0.295 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.705 0.295 0.000
F11 Mental and behavioural disorders due to use of opioids
0.705 0.295 0.000
F40 Phobic anxiety disorders
0.705 0.295 0.000
C91.1 Chronic lymphocytic leukaemia
0.705 0.295 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.704 0.296 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.704 0.296 0.000
C91.0 Acute lymphoblastic leukaemia
0.704 0.296 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.702 0.297 0.000
J96 Respiratory failure, not elsewhere classified
0.702 0.297 0.000
D59 Acquired haemolytic anaemia
0.702 0.298 0.000
G54 Nerve root and plexus disorders
0.702 0.298 0.000
J11 Influenza, virus not identified
0.701 0.299 0.000
S00-S09 Injuries to the head
0.701 0.299 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.700 0.300 0.000
X59 Exposure to unspecified factor
0.699 0.301 0.000
C78.7 Secondary malignant neoplasm of liver
0.699 0.301 0.000
E16 Other disorders of pancreatic internal secretion
0.699 0.301 0.000
Y43.9 Primarily systemic agent, unspecified
0.698 0.302 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.698 0.302 0.000
Y43.6 Enzymes, not elsewhere classified
0.698 0.302 0.000
Y43.5 Acidifying and alkalising agents
0.698 0.302 0.000
Y43.2 Antineoplastic natural products
0.698 0.302 0.000
Y43.0 Antiallergic and antiemetic drugs
0.698 0.302 0.000
D69.9 Haemorrhagic condition, unspecified
0.696 0.303 0.000
D69.8 Other specified haemorrhagic conditions
0.696 0.303 0.000
D69.4 Other primary thrombocytopenia
0.696 0.303 0.000
D69.2 Other nonthrombocytopenic purpura
0.696 0.303 0.000
D69.1 Qualitative platelet defects
0.696 0.303 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.696 0.304 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.696 0.304 0.000
C71.9 Brain, unspecified
0.695 0.305 0.000
Y52 Agents primarily affecting the cardiovascular system
0.695 0.305 0.000
J98.6 Disorders of diaphragm
0.694 0.306 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.694 0.306 0.000
J98.3 Compensatory emphysema
0.694 0.306 0.000
J98.2 Interstitial emphysema
0.694 0.306 0.000
M47 Spondylosis
0.694 0.306 0.000
G58 Other mononeuropathies
0.693 0.307 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.692 0.308 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.692 0.308 0.000
G92 Toxic encephalopathy
0.692 0.308 0.000
E29 Testicular dysfunction
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.690 0.309 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.690 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.690 0.309 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.690 0.309 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.690 0.309 0.000
T36 Poisoning by systemic antibiotics
0.690 0.309 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.690 0.310 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.690 0.310 0.000
M25.4 Effusion of joint
0.689 0.310 0.000
M25.58 Pain in joint (Other)
0.689 0.311 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.689 0.311 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.689 0.311 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.689 0.311 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.689 0.311 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.689 0.311 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.689 0.311 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.689 0.311 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.689 0.311 0.000
V10 Pedal cyclist injured in collision with pedestrian or animal
0.689 0.311 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.688 0.312 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.688 0.312 0.000
A80-A89 Viral infections of the central nervous system
0.687 0.313 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.687 0.313 0.000
G50.8 Other disorders of trigeminal nerve
0.687 0.313 0.000
G50.1 Atypical facial pain
0.687 0.313 0.000
F48 Other neurotic disorders
0.687 0.313 0.000
F44 Dissociative [conversion] disorders
0.687 0.313 0.000
F42 Obsessive-compulsive disorder
0.687 0.313 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
E84 Cystic fibrosis
0.684 0.315 0.000
E79 Disorders of purine and pyrimidine metabolism
0.684 0.315 0.000
E77 Disorders of glycoprotein metabolism
0.684 0.315 0.000
E76 Disorders of glycosaminoglycan metabolism
0.684 0.315 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.684 0.315 0.000
E74 Other disorders of carbohydrate metabolism
0.684 0.315 0.000
E72 Other disorders of amino-acid metabolism
0.684 0.315 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.684 0.315 0.000
E70 Disorders of aromatic amino-acid metabolism
0.684 0.315 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.684 0.315 0.000
M41.8 Other forms of scoliosis
0.684 0.315 0.000
T92 Sequelae of injuries of upper limb
0.684 0.316 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.684 0.316 0.000
G24 Dystonia
0.683 0.317 0.000
C60-C63 Malignant neoplasms of male genital organs
0.683 0.317 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.683 0.317 0.000
Y43.4 Immunosuppressive agents
0.682 0.318 0.000
S29 Other and unspecified injuries of thorax
0.682 0.318 0.000
T65 Toxic effect of other and unspecified substances
0.682 0.318 0.000
T62 Toxic effect of other noxious substances eaten as food
0.682 0.318 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.682 0.318 0.000
T60 Toxic effect of pesticides
0.682 0.318 0.000
T57 Toxic effect of other inorganic substances
0.682 0.318 0.000
T56 Toxic effect of metals
0.682 0.318 0.000
T54 Toxic effect of corrosive substances
0.682 0.318 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.682 0.318 0.000
T52 Toxic effect of organic solvents
0.682 0.318 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.682 0.318 0.000
T55 Toxic effect of soaps and detergents
0.682 0.318 0.000
X60-X84 Intentional self-harm
0.682 0.318 0.000
W50.9 Unspecified place
0.682 0.318 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.681 0.319 0.000
E87.4 Mixed disorder of acid-base balance
0.681 0.319 0.000
J91 Pleural effusion in conditions classified elsewhere
0.681 0.319 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.681 0.319 0.000
S41 Open wound of shoulder and upper arm
0.681 0.319 0.000
T51.9 Alcohol, unspecified
0.680 0.319 0.000
F45 Somatoform disorders
0.680 0.320 0.000
S19 Other and unspecified injuries of neck
0.680 0.320 0.000
F10.8 Other mental and behavioural disorders
0.678 0.321 0.000
F10.7 Residual and late-onset psychotic disorder
0.678 0.321 0.000
F10.6 Amnesic syndrome
0.678 0.321 0.000
F10.5 Psychotic disorder
0.678 0.321 0.000
C25 Malignant neoplasm of pancreas
0.678 0.322 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.678 0.322 0.000
E80.4 Gilbert's syndrome
0.678 0.322 0.000
S99 Other and unspecified injuries of ankle and foot
0.677 0.322 0.000
B37 Candidiasis
0.677 0.323 0.000
C50.6 Axillary tail of breast
0.677 0.323 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.676 0.324 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.324 0.000
M25.53 Pain in joint (Forearm)
0.676 0.324 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.675 0.325 0.000
M43 Other deforming dorsopathies
0.675 0.325 0.000
C53 Malignant neoplasm of cervix uteri
0.673 0.327 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.673 0.327 0.000
G95 Other diseases of spinal cord
0.672 0.328 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.672 0.328 0.000
M93 Other osteochondropathies
0.672 0.328 0.000
G93.7 Reye's syndrome
0.672 0.328 0.000
G93.5 Compression of brain
0.672 0.328 0.000
C01 Malignant neoplasm of base of tongue
0.671 0.329 0.000
M21.2 Flexion deformity
0.671 0.329 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.671 0.329 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.671 0.329 0.000
C67 Malignant neoplasm of bladder
0.671 0.329 0.000
M80 Osteoporosis with pathological fracture
0.671 0.329 0.000
S01 Open wound of head
0.671 0.329 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.670 0.330 0.000
C95 Leukaemia of unspecified cell type
0.670 0.330 0.000
C94 Other leukaemias of specified cell type
0.670 0.330 0.000
C93 Monocytic leukaemia
0.670 0.330 0.000
C88 Malignant immunoproliferative diseases
0.670 0.330 0.000
C86 Other specified types of T/NK-cell lymphoma
0.670 0.330 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.670 0.330 0.000
G51.0 Bell's palsy
0.669 0.331 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.669 0.331 0.000
Y57.5 X-ray contrast media
0.669 0.331 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.669 0.331 0.000
V18.4 Driver injured in traffic accident
0.669 0.331 0.000
V18.5 Passenger injured in traffic accident
0.669 0.331 0.000
V18.3 Person injured while boarding or alighting
0.669 0.331 0.000
V18.1 Passenger injured in nontraffic accident
0.669 0.331 0.000
F68 Other disorders of adult personality and behaviour
0.668 0.331 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.668 0.331 0.000
F65 Disorders of sexual preference
0.668 0.331 0.000
F64 Gender identity disorders
0.668 0.331 0.000
F63 Habit and impulse disorders
0.668 0.331 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.668 0.331 0.000
F69 Unspecified disorder of adult personality and behaviour
0.668 0.331 0.000
F61 Mixed and other personality disorders
0.668 0.331 0.000
S50-S59 Injuries to the elbow and forearm
0.667 0.333 0.000
M34.8 Other forms of systemic sclerosis
0.665 0.335 0.000
G91.9 Hydrocephalus, unspecified
0.665 0.335 0.000
B99-B99 Other infectious diseases
0.664 0.336 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.664 0.336 0.000
B65-B83 Helminthiases
0.664 0.336 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.664 0.336 0.000
A75-A79 Rickettsioses
0.664 0.336 0.000
A70-A74 Other diseases caused by chlamydiae
0.664 0.336 0.000
A65-A69 Other spirochaetal diseases
0.664 0.336 0.000
A20-A28 Certain zoonotic bacterial diseases
0.664 0.336 0.000
A15-A19 Tuberculosis
0.664 0.336 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.664 0.336 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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