TreeWAS – Variant ID: rs2815308

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.994	0.006	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.990	0.010	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.986	0.014	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.978	0.022	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.974	0.026	0.000
S80-S89 Injuries to the knee and lower leg	0.973	0.027	0.000
Chapter VII Diseases of the eye and adnexa	0.971	0.029	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.969	0.031	0.000
Chapter I Certain infectious and parasitic diseases	0.963	0.037	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.961	0.039	0.000
S20-S29 Injuries to the thorax	0.960	0.040	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.950	0.050	0.000
H40-H42 Glaucoma	0.940	0.060	0.000
Chapter X Diseases of the respiratory system	0.940	0.060	0.000
Y84.8 Other medical procedures	0.936	0.064	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.933	0.067	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.931	0.069	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.930	0.070	0.000
J00-J06 Acute upper respiratory infections	0.928	0.072	0.000
Y43 Primarily systemic agents	0.928	0.072	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.926	0.074	0.000
J09-J18 Influenza and pneumonia	0.921	0.079	0.000
S32 Fracture of lumbar spine and pelvis	0.920	0.080	0.000
H40 Glaucoma	0.919	0.081	0.000
Q60-Q64 Congenital malformations of the urinary system	0.919	0.081	0.000
B25-B34 Other viral diseases	0.912	0.088	0.000
Y43.3 Other antineoplastic drugs	0.907	0.093	0.000
L05 Pilonidal cyst	0.906	0.094	0.000
Y57 Other and unspecified drugs and medicaments	0.905	0.095	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.905	0.095	0.000
S82 Fracture of lower leg, including ankle	0.901	0.099	0.000
Chapter XXII Codes for special purposes	0.901	0.099	0.000
S70-S79 Injuries to the hip and thigh	0.897	0.103	0.000
E70-E90 Metabolic disorders	0.891	0.109	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.890	0.110	0.000
H40.1 Primary open-angle glaucoma	0.890	0.110	0.000
E20-E35 Disorders of other endocrine glands	0.888	0.112	0.000
E00-E07 Disorders of thyroid gland	0.883	0.117	0.000
W20-W49 Exposure to inanimate mechanical forces	0.882	0.118	0.000
L40-L45 Papulosquamous disorders	0.876	0.124	0.000
S82.0 Fracture of patella	0.874	0.126	0.000
Chapter VI Diseases of the nervous system	0.871	0.129	0.000
B34 Viral infection of unspecified site	0.869	0.131	0.000
S31 Open wound of abdomen, lower back and pelvis	0.866	0.134	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.864	0.136	0.000
H10-H13 Disorders of conjunctiva	0.864	0.136	0.000
Q63 Other congenital malformations of kidney	0.862	0.138	0.000
J60-J70 Lung diseases due to external agents	0.860	0.140	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.859	0.141	0.000
H30-H36 Disorders of choroid and retina	0.849	0.144	0.008
S22.0 Fracture of thoracic vertebra	0.856	0.144	0.000
Y84.2 Radiological procedure and radiotherapy	0.856	0.144	0.000
S82.00 Fracture of patella (closed)	0.854	0.146	0.000
S86 Injury of muscle and tendon at lower leg level	0.852	0.148	0.000
L03 Cellulitis	0.849	0.151	0.000
S22.3 Fracture of rib	0.849	0.151	0.000
S89 Other and unspecified injuries of lower leg	0.848	0.152	0.000
D60-D64 Aplastic and other anaemias	0.848	0.152	0.000
J02 Acute pharyngitis	0.848	0.152	0.000
J03 Acute tonsillitis	0.836	0.164	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.836	0.164	0.000
L05.9 Pilonidal cyst without abscess	0.835	0.165	0.000
E10-E14 Diabetes mellitus	0.828	0.172	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.826	0.174	0.000
J18 Pneumonia, organism unspecified	0.825	0.175	0.000
Y57.5 X-ray contrast media	0.825	0.175	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.825	0.175	0.000
J17 Pneumonia in diseases classified elsewhere	0.825	0.175	0.000
S32.5 Fracture of pubis	0.823	0.177	0.000
W00-W19 Falls	0.823	0.177	0.000
Y40 Systemic antibiotics	0.822	0.178	0.000
Q63.0 Accessory kidney	0.821	0.179	0.000
B34.9 Viral infection, unspecified	0.820	0.180	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.820	0.180	0.000
J06.9 Acute upper respiratory infection, unspecified	0.818	0.182	0.000
V80-V89 Other land transport accidents	0.818	0.182	0.000
H16 Keratitis	0.817	0.183	0.000
S79 Other and unspecified injuries of hip and thigh	0.816	0.184	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.814	0.185	0.000
E04 Other non-toxic goitre	0.814	0.186	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.812	0.188	0.000
S81 Open wound of lower leg	0.810	0.190	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.803	0.197	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.803	0.197	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.799	0.201	0.000
H18 Other disorders of cornea	0.798	0.202	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.796	0.204	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.795	0.205	0.000
Q61 Cystic kidney disease	0.793	0.207	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.793	0.207	0.000
H11 Other disorders of conjunctiva	0.793	0.207	0.000
X50-X57 Overexertion, travel and privation	0.793	0.207	0.000
Chapter VIII Diseases of the ear and mastoid process	0.792	0.208	0.000
Q76 Congenital malformations of spine and bony thorax	0.792	0.208	0.000
J02.9 Acute pharyngitis, unspecified	0.791	0.209	0.000
S22.30 Fracture of rib (closed)	0.790	0.210	0.000
H35 Other retinal disorders	0.789	0.210	0.001
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.789	0.211	0.000
D69 Purpura and other haemorrhagic conditions	0.789	0.211	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.788	0.212	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.788	0.212	0.000
B50-B64 Protozoal diseases	0.787	0.213	0.000
E04.1 Non-toxic single thyroid nodule	0.785	0.215	0.000
B99-B99 Other infectious diseases	0.784	0.216	0.000
J69 Pneumonitis due to solids and liquids	0.783	0.217	0.000
J10 Influenza due to identified influenza virus	0.783	0.217	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.782	0.218	0.000
G81 Hemiplegia	0.780	0.220	0.000
Q50-Q56 Congenital malformations of genital organs	0.780	0.220	0.000
W50-W64 Exposure to animate mechanical forces	0.777	0.223	0.000
L08 Other local infections of skin and subcutaneous tissue	0.776	0.224	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.776	0.224	0.000
E50-E64 Other nutritional deficiencies	0.774	0.226	0.000
E11 Non-insulin-dependent diabetes mellitus	0.772	0.228	0.000
J03.9 Acute tonsillitis, unspecified	0.770	0.230	0.000
L40 Psoriasis	0.770	0.230	0.000
Y59 Other and unspecified vaccines and biological substances	0.769	0.231	0.000
H40.2 Primary angle-closure glaucoma	0.769	0.231	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.767	0.233	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.766	0.234	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.764	0.236	0.000
L03.3 Cellulitis of trunk	0.764	0.236	0.000
S82.3 Fracture of lower end of tibia	0.761	0.239	0.000
Y48 Anaesthetics and therapeutic gases	0.761	0.239	0.000
S89.9 Unspecified injury of lower leg	0.759	0.241	0.000
S79.9 Unspecified injury of hip and thigh	0.758	0.242	0.000
H40.5 Glaucoma secondary to other eye disorders	0.758	0.242	0.000
D73 Diseases of spleen	0.757	0.243	0.000
L50-L54 Urticaria and erythema	0.755	0.244	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.754	0.246	0.000
S81.0 Open wound of knee	0.753	0.246	0.000
S32.50 Fracture of pubis (closed)	0.753	0.247	0.000
V20-V29 Motorcycle rider injured in transport accident	0.752	0.248	0.000
S60-S69 Injuries to the wrist and hand	0.752	0.248	0.000
H21 Other disorders of iris and ciliary body	0.752	0.248	0.000
Y44 Agents primarily affecting blood constituents	0.750	0.250	0.000
S31.1 Open wound of abdominal wall	0.749	0.251	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.748	0.252	0.000
E87.2 Acidosis	0.746	0.254	0.000
S50-S59 Injuries to the elbow and forearm	0.746	0.254	0.000
H35.3 Degeneration of macula and posterior pole	0.745	0.255	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.745	0.255	0.000
E87.3 Alkalosis	0.745	0.255	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.742	0.258	0.000
G81.9 Hemiplegia, unspecified	0.741	0.259	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.740	0.260	0.000
D69.6 Thrombocytopenia, unspecified	0.738	0.262	0.000
S22.5 Flail chest	0.737	0.263	0.000
V10-V19 Pedal cyclist injured in transport accident	0.737	0.263	0.000
S27 Injury of other and unspecified intrathoracic organs	0.732	0.268	0.000
S90-S99 Injuries to the ankle and foot	0.732	0.268	0.000
H40.9 Glaucoma, unspecified	0.728	0.272	0.000
S32.1 Fracture of sacrum	0.728	0.272	0.000
J69.0 Pneumonitis due to food and vomit	0.728	0.272	0.000
Y84.4 Aspiration of fluid	0.727	0.273	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.725	0.275	0.000
A65-A69 Other spirochaetal diseases	0.724	0.275	0.000
S82.4 Fracture of fibula alone	0.723	0.277	0.000
U80 Agent resistant to penicillin and related antibiotics	0.723	0.277	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.722	0.278	0.000
Y57.9 Drug or medicament, unspecified	0.721	0.279	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.721	0.279	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.720	0.279	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.720	0.279	0.000
L20-L30 Dermatitis and eczema	0.720	0.279	0.000
E21.0 Primary hyperparathyroidism	0.720	0.280	0.000
X10-X19 Contact with heat and hot substances	0.720	0.280	0.000
E11.4 With neurological complications	0.720	0.280	0.000
H31 Other disorders of choroid	0.714	0.282	0.005
B90-B94 Sequelae of infectious and parasitic diseases	0.718	0.282	0.000
E40-E46 Malnutrition	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.717	0.283	0.000
Y10-Y34 Event of undetermined intent	0.717	0.283	0.000
Y00-Y09 Assault	0.717	0.283	0.000
X85-X99 Assault	0.717	0.283	0.000
X30-X39 Exposure to forces of nature	0.717	0.283	0.000
X00-X09 Exposure to smoke, fire and flames	0.717	0.283	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283	0.000
W75-W84 Other accidental threats to breathing	0.717	0.283	0.000
W65-W74 Accidental drowning and submersion	0.717	0.283	0.000
V98-V99 Other and unspecified transport accidents	0.717	0.283	0.000
V95-V97 Air and space transport accidents	0.717	0.283	0.000
V90-V94 Water transport accidents	0.717	0.283	0.000
V70-V79 Bus occupant injured in transport accident	0.717	0.283	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283	0.000
V01-V09 Pedestrian injured in transport accident	0.717	0.283	0.000
H20 Iridocyclitis	0.716	0.284	0.000
B34.4 Papovirus infection, unspecified	0.716	0.284	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.715	0.285	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.714	0.285	0.000
J04 Acute laryngitis and tracheitis	0.714	0.286	0.000
T33-T35 Frostbite	0.714	0.286	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286	0.000
T00-T07 Injuries involving multiple body regions	0.714	0.286	0.000
S20 Superficial injury of thorax	0.714	0.286	0.000
L10-L14 Bullous disorders	0.713	0.287	0.000
E11.5 With peripheral circulatory complications	0.712	0.288	0.000
Q65 Congenital deformities of hip	0.711	0.289	0.000
H18.4 Corneal degeneration	0.710	0.290	0.000
H16.0 Corneal ulcer	0.710	0.290	0.000
S10-S19 Injuries to the neck	0.710	0.290	0.000
A80-A89 Viral infections of the central nervous system	0.710	0.290	0.000
A00-A09 Intestinal infectious diseases	0.710	0.290	0.000
W25 Contact with sharp glass	0.709	0.291	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.709	0.291	0.000
J13 Pneumonia due to Streptococcus pneumoniae	0.709	0.291	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.708	0.292	0.000
Y95 Nosocomial condition	0.708	0.292	0.000
B00 Herpesviral [herpes simplex] infections	0.708	0.292	0.000
L04 Acute lymphadenitis	0.707	0.293	0.000
L01 Impetigo	0.707	0.293	0.000
L00 Staphylococcal scalded skin syndrome	0.707	0.293	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.707	0.293	0.000
L03.0 Cellulitis of finger and toe	0.706	0.294	0.000
H80-H83 Diseases of inner ear	0.706	0.294	0.000
S32.4 Fracture of acetabulum	0.704	0.296	0.000
X60-X84 Intentional self-harm	0.703	0.297	0.000
E87.0 Hyperosmolality and hypernatraemia	0.703	0.297	0.000
S82.6 Fracture of lateral malleolus	0.702	0.298	0.000
X20-X29 Contact with venomous animals and plants	0.701	0.299	0.000
G51 Facial nerve disorders	0.701	0.299	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.701	0.299	0.000
S37 Injury of urinary and pelvic organs	0.701	0.299	0.000
S36 Injury of intra-abdominal organs	0.701	0.299	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.701	0.299	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.701	0.299	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.701	0.299	0.000
B65-B83 Helminthiases	0.700	0.300	0.000
W22 Striking against or struck by other objects	0.700	0.300	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.699	0.301	0.000
E88 Other metabolic disorders	0.699	0.301	0.000
H34 Retinal vascular occlusions	0.695	0.301	0.004
Y58 Bacterial vaccines	0.698	0.302	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.698	0.302	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.698	0.302	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.698	0.302	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.698	0.302	0.000
L05.0 Pilonidal cyst with abscess	0.698	0.302	0.000
S88 Traumatic amputation of lower leg	0.698	0.302	0.000
S87 Crushing injury of lower leg	0.698	0.302	0.000
S85 Injury of blood vessels at lower leg level	0.698	0.302	0.000
S84 Injury of nerves at lower leg level	0.698	0.302	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.304	0.000
B25 Cytomegaloviral disease	0.696	0.304	0.000
E87.7 Fluid overload	0.696	0.304	0.000
S22.4 Multiple fractures of ribs	0.695	0.305	0.000
H11.3 Conjunctival haemorrhage	0.695	0.305	0.000
Y84.1 Kidney dialysis	0.695	0.305	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.695	0.305	0.000
Q35-Q37 Cleft lip and cleft palate	0.695	0.305	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.695	0.305	0.000
G83 Other paralytic syndromes	0.693	0.307	0.000
L60-L75 Disorders of skin appendages	0.692	0.308	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.690	0.310	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.690	0.310	0.000
A75-A79 Rickettsioses	0.690	0.310	0.000
A70-A74 Other diseases caused by chlamydiae	0.690	0.310	0.000
A20-A28 Certain zoonotic bacterial diseases	0.690	0.310	0.000
A15-A19 Tuberculosis	0.690	0.310	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.688	0.312	0.000
S26 Injury of heart	0.688	0.312	0.000
S25 Injury of blood vessels of thorax	0.688	0.312	0.000
S24 Injury of nerves and spinal cord at thorax level	0.688	0.312	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.688	0.312	0.000
S21 Open wound of thorax	0.688	0.312	0.000
J18.9 Pneumonia, unspecified	0.688	0.312	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.687	0.313	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.687	0.313	0.000
D62 Acute posthaemorrhagic anaemia	0.687	0.313	0.000
J17.3 Pneumonia in parasitic diseases	0.686	0.314	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.686	0.314	0.000
E11.0 With coma	0.685	0.315	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.685	0.315	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.684	0.316	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.684	0.316	0.000
Y57.8 Other drugs and medicaments	0.684	0.316	0.000
W29 Contact with other powered hand tools and household machinery	0.684	0.316	0.000
W44 Foreign body entering into or through eye or natural orifice	0.683	0.317	0.000
E65-E68 Obesity and other hyperalimentation	0.683	0.317	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.682	0.318	0.000
Y40.0 Penicillins	0.682	0.318	0.000
V40-V49 Car occupant injured in transport accident	0.681	0.319	0.000
Y84.9 Medical procedure, unspecified	0.681	0.319	0.000
Y84.7 Blood-sampling	0.681	0.319	0.000
Y84.5 Insertion of gastric or duodenal sound	0.681	0.319	0.000
Y84.3 Shock therapy	0.681	0.319	0.000
W10 Fall on and from stairs and steps	0.681	0.319	0.000
L43 Lichen planus	0.679	0.321	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.679	0.321	0.000
G70-G73 Diseases of myoneural junction and muscle	0.678	0.322	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.678	0.322	0.000
J18.0 Bronchopneumonia, unspecified	0.678	0.322	0.000
S22.1 Multiple fractures of thoracic spine	0.678	0.322	0.000
S32.3 Fracture of ilium	0.677	0.323	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.677	0.323	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.677	0.323	0.000
E29 Testicular dysfunction	0.675	0.324	0.000
T91 Sequelae of injuries of neck and trunk	0.675	0.325	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.674	0.326	0.000
H42 Glaucoma in diseases classified elsewhere	0.674	0.326	0.000
E23 Hypofunction and other disorders of pituitary gland	0.674	0.326	0.000
S70 Superficial injury of hip and thigh	0.674	0.326	0.000
J14 Pneumonia due to Haemophilus influenzae	0.674	0.326	0.000
E28 Ovarian dysfunction	0.673	0.327	0.000
E26 Hyperaldosteronism	0.671	0.328	0.000
Y43.0 Antiallergic and antiemetic drugs	0.671	0.329	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.670	0.330	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.670	0.330	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.670	0.330	0.000
D55-D59 Haemolytic anaemias	0.669	0.331	0.000
S64 Injury of nerves at wrist and hand level	0.668	0.331	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.668	0.332	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.668	0.332	0.000
S22.9 Fracture of bony thorax, part unspecified	0.667	0.333	0.000
S22.8 Fracture of other parts of bony thorax	0.667	0.333	0.000
Y43.9 Primarily systemic agent, unspecified	0.665	0.335	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.665	0.335	0.000
Y43.6 Enzymes, not elsewhere classified	0.665	0.335	0.000
Y43.5 Acidifying and alkalising agents	0.665	0.335	0.000
Y43.2 Antineoplastic natural products	0.665	0.335	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.664	0.336	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.664	0.336	0.000
H15 Disorders of sclera	0.664	0.336	0.000
G30-G32 Other degenerative diseases of the nervous system	0.663	0.337	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.663	0.337	0.000
S72 Fracture of femur	0.662	0.338	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.661	0.339	0.000
B59 Pneumocystosis	0.661	0.339	0.000
S82.30 Fracture of lower end of tibia (closed)	0.661	0.339	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.660	0.340	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.660	0.340	0.000
J12 Viral pneumonia, not elsewhere classified	0.660	0.340	0.000
J09 Influenza due to certain identified influenza virus	0.660	0.340	0.000
S32.2 Fracture of coccyx	0.660	0.340	0.000
Q61.2 Polycystic kidney, adult type	0.660	0.340	0.000
H40.6 Glaucoma secondary to drugs	0.659	0.341	0.000
H40.4 Glaucoma secondary to eye inflammation	0.659	0.341	0.000
H40.3 Glaucoma secondary to eye trauma	0.659	0.341	0.000
Q64 Other congenital malformations of urinary system	0.659	0.341	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.659	0.341	0.000
W06 Fall involving bed	0.659	0.341	0.000
Q76.0 Spina bifida occulta	0.658	0.342	0.000
E87.5 Hyperkalaemia	0.658	0.342	0.000
B99 Other and unspecified infectious diseases	0.656	0.344	0.000
Q00-Q07 Congenital malformations of the nervous system	0.655	0.345	0.000
U51 Admission status on psychiatric patients	0.655	0.345	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.654	0.346	0.000
B33 Other viral diseases, not elsewhere classified	0.654	0.346	0.000
B30 Viral conjunctivitis	0.654	0.346	0.000
B27 Infectious mononucleosis	0.654	0.346	0.000
B26 Mumps	0.654	0.346	0.000
Q66 Congenital deformities of feet	0.654	0.346	0.000
E86 Volume depletion	0.653	0.347	0.000
S29 Other and unspecified injuries of thorax	0.652	0.348	0.000
E20 Hypoparathyroidism	0.650	0.349	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.650	0.350	0.000
Y84.0 Cardiac catheterisation	0.649	0.350	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.649	0.351	0.000
W17 Other fall from one level to another	0.649	0.351	0.000
Y57.7 Vitamins, not elsewhere classified	0.649	0.351	0.000
Y57.6 Other diagnostic agents	0.649	0.351	0.000
Y57.4 Pharmaceutical excipients	0.649	0.351	0.000
Y57.3 Alcohol deterrents	0.649	0.351	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.649	0.351	0.000
Y57.1 Lipotropic drugs	0.649	0.351	0.000
Y57.0 Appetite depressants [anorectics]	0.649	0.351	0.000
H16.9 Keratitis, unspecified	0.648	0.352	0.000
W08 Fall involving other furniture	0.648	0.352	0.000
H35.0 Background retinopathy and retinal vascular changes	0.647	0.352	0.000
E34 Other endocrine disorders	0.647	0.353	0.000
D72 Other disorders of white blood cells	0.647	0.353	0.000
S82.9 Fracture of lower leg, part unspecified	0.646	0.354	0.000
S82.7 Multiple fractures of lower leg	0.646	0.354	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.645	0.355	0.000
D73.5 Infarction of spleen	0.644	0.356	0.000
S78 Traumatic amputation of hip and thigh	0.643	0.356	0.000
S77 Crushing injury of hip and thigh	0.643	0.356	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.643	0.356	0.000
S75 Injury of blood vessels at hip and thigh level	0.643	0.356	0.000
S74 Injury of nerves at hip and thigh level	0.643	0.356	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.643	0.356	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.642	0.358	0.000
J18.1 Lobar pneumonia, unspecified	0.641	0.359	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.640	0.360	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.640	0.360	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.640	0.360	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.640	0.360	0.000
E11.2 With renal complications	0.640	0.360	0.000
Q61.3 Polycystic kidney, unspecified	0.640	0.360	0.000
H55-H59 Other disorders of eye and adnexa	0.639	0.361	0.000
E85 Amyloidosis	0.638	0.361	0.000
E84 Cystic fibrosis	0.638	0.361	0.000
E79 Disorders of purine and pyrimidine metabolism	0.638	0.361	0.000
E77 Disorders of glycoprotein metabolism	0.638	0.361	0.000
E76 Disorders of glycosaminoglycan metabolism	0.638	0.361	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.638	0.361	0.000
E74 Other disorders of carbohydrate metabolism	0.638	0.361	0.000
E72 Other disorders of amino-acid metabolism	0.638	0.361	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.638	0.361	0.000
E70 Disorders of aromatic amino-acid metabolism	0.638	0.361	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.638	0.361	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.638	0.362	0.000
Q78 Other osteochondrodysplasias	0.638	0.362	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.638	0.362	0.000
Q75 Other congenital malformations of skull and face bones	0.638	0.362	0.000
Q74 Other congenital malformations of limb(s)	0.638	0.362	0.000
Q73 Reduction defects of unspecified limb	0.638	0.362	0.000
Q72 Reduction defects of lower limb	0.638	0.362	0.000
Q71 Reduction defects of upper limb	0.638	0.362	0.000
Q70 Syndactyly	0.638	0.362	0.000
Q69 Polydactyly	0.638	0.362	0.000
Q68 Other congenital musculoskeletal deformities	0.638	0.362	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.638	0.362	0.000
D73.0 Hyposplenism	0.638	0.362	0.000
L03.2 Cellulitis of face	0.638	0.362	0.000
W20 Struck by thrown, projected or falling object	0.637	0.362	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.637	0.363	0.000
E87.6 Hypokalaemia	0.637	0.363	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.636	0.363	0.000
E32 Diseases of thymus	0.636	0.363	0.000
E31 Polyglandular dysfunction	0.636	0.363	0.000
E30 Disorders of puberty, not elsewhere classified	0.636	0.363	0.000
E25 Adrenogenital disorders	0.636	0.363	0.000
E24 Cushing's syndrome	0.636	0.363	0.000
T18 Foreign body in alimentary tract	0.636	0.364	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.635	0.364	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.635	0.365	0.000
E21.3 Hyperparathyroidism, unspecified	0.635	0.365	0.000
H17 Corneal scars and opacities	0.635	0.365	0.000
Y40.9 Systemic antibiotic, unspecified	0.635	0.365	0.000
S80 Superficial injury of lower leg	0.635	0.365	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.633	0.367	0.000
E00 Congenital iodine-deficiency syndrome	0.633	0.367	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.633	0.367	0.000
G80 Infantile cerebral palsy	0.633	0.367	0.000
H11.8 Other specified disorders of conjunctiva	0.632	0.368	0.000
S67 Crushing injury of wrist and hand	0.632	0.368	0.000
W46 Contact with hypodermic needle	0.632	0.368	0.000
W45 Foreign body or object entering through skin	0.632	0.368	0.000
W43 Exposure to vibration	0.632	0.368	0.000
W42 Exposure to noise	0.632	0.368	0.000
W41 Exposure to high-pressure jet	0.632	0.368	0.000
W40 Explosion of other materials	0.632	0.368	0.000
W39 Discharge of firework	0.632	0.368	0.000
W38 Explosion and rupture of other specified pressurised devices	0.632	0.368	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.632	0.368	0.000
W36 Explosion and rupture of gas cylinder	0.632	0.368	0.000
W35 Explosion and rupture of boiler	0.632	0.368	0.000
W34 Discharge from other and unspecified firearms	0.632	0.368	0.000
W33 Rifle, shotgun and larger firearm discharge	0.632	0.368	0.000
W32 Handgun discharge	0.632	0.368	0.000
W31 Contact with other and unspecified machinery	0.632	0.368	0.000
W30 Contact with agricultural machinery	0.632	0.368	0.000
W28 Contact with powered lawn mower	0.632	0.368	0.000
W27 Contact with nonpowered hand tool	0.632	0.368	0.000
W26 Contact with knife, sword or dagger	0.632	0.368	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.632	0.368	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.632	0.368	0.000
W55 Bitten or struck by other mammals	0.631	0.369	0.000
B15-B19 Viral hepatitis	0.630	0.369	0.000
D69.5 Secondary thrombocytopenia	0.630	0.370	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.630	0.370	0.000
A04 Other bacterial intestinal infections	0.629	0.371	0.000
L44 Other papulosquamous disorders	0.628	0.372	0.000
L41 Parapsoriasis	0.628	0.372	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.628	0.372	0.000
L42 Pityriasis rosea	0.628	0.372	0.000
G82 Paraplegia and tetraplegia	0.628	0.372	0.000
S82.01 Fracture of patella (open)	0.626	0.373	0.000
S71 Open wound of hip and thigh	0.626	0.374	0.000
L40.0 Psoriasis vulgaris	0.626	0.374	0.000
B35-B49 Mycoses	0.624	0.375	0.000
H31.8 Other specified disorders of choroid	0.622	0.376	0.002
U81 Agent resistant to vancomycin and related antibiotics	0.624	0.376	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.623	0.377	0.000
B34.8 Other viral infections of unspecified site	0.623	0.377	0.000
B34.3 Parvovirus infection, unspecified	0.623	0.377	0.000
B34.2 Coronavirus infection, unspecified	0.623	0.377	0.000
B34.1 Enterovirus infection, unspecified	0.623	0.377	0.000
B34.0 Adenovirus infection, unspecified	0.623	0.377	0.000
Y59.3 Immunoglobulin	0.623	0.377	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.621	0.379	0.000
S31.5 Open wound of other and unspecified external genital organs	0.621	0.379	0.000
S31.4 Open wound of vagina and vulva	0.621	0.379	0.000
S31.3 Open wound of scrotum and testes	0.621	0.379	0.000
S31.2 Open wound of penis	0.621	0.379	0.000
S31.0 Open wound of lower back and pelvis	0.621	0.379	0.000
S68 Traumatic amputation of wrist and hand	0.621	0.379	0.000
H65-H75 Diseases of middle ear and mastoid	0.621	0.379	0.000
D73.8 Other diseases of spleen	0.620	0.380	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.620	0.380	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.619	0.381	0.000
J06.0 Acute laryngopharyngitis	0.619	0.381	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.619	0.381	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations