TreeWAS – Variant ID: rs16883538

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter XX External causes of morbidity and mortality	0.999	0.001	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.999	0.001	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.997	0.003	0.000
M50-M54 Other dorsopathies	0.997	0.003	0.000
M54 Dorsalgia	0.996	0.004	0.000
S70-S79 Injuries to the hip and thigh	0.989	0.011	0.000
S72 Fracture of femur	0.980	0.020	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.979	0.021	0.000
S72.0 Fracture of neck of femur	0.976	0.024	0.000
M54.5 Low back pain	0.975	0.025	0.000
S72.00 Fracture of neck of femur (closed)	0.974	0.026	0.000
M80-M85 Disorders of bone density and structure	0.973	0.027	0.000
T92 Sequelae of injuries of upper limb	0.973	0.027	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.970	0.030	0.000
M86-M90 Other osteopathies	0.968	0.032	0.000
Chapter I Certain infectious and parasitic diseases	0.965	0.035	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.964	0.036	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.962	0.038	0.000
M45-M49 Spondylopathies	0.953	0.047	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.951	0.049	0.000
A00-A09 Intestinal infectious diseases	0.949	0.051	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.947	0.053	0.000
Y86 Sequelae of other accidents	0.943	0.057	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.937	0.063	0.000
M54.9 Dorsalgia, unspecified	0.936	0.064	0.000
M89 Other disorders of bone	0.927	0.073	0.000
T91 Sequelae of injuries of neck and trunk	0.923	0.077	0.000
T42.4 Benzodiazepines	0.922	0.078	0.000
T93 Sequelae of injuries of lower limb	0.919	0.081	0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.917	0.083	0.000
W20-W49 Exposure to inanimate mechanical forces	0.916	0.084	0.000
M46 Other inflammatory spondylopathies	0.913	0.087	0.000
Y42.7 Androgens and anabolic congeners	0.896	0.104	0.000
W00-W19 Falls	0.895	0.105	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.891	0.109	0.000
A09.9 Gastroenteritis and colitis of unspecified origin	0.891	0.109	0.000
T17 Foreign body in respiratory tract	0.889	0.111	0.000
M54.2 Cervicalgia	0.886	0.114	0.000
Y42.5 Other oestrogens and progestogens	0.886	0.114	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.885	0.115	0.000
M54.3 Sciatica	0.885	0.115	0.000
T43.2 Other and unspecified antidepressants	0.880	0.120	0.000
M54.56 Low back pain (Lumbar region)	0.877	0.123	0.000
T92.1 Sequelae of fracture of arm	0.875	0.125	0.000
T93.2 Sequelae of other fractures of lower limb	0.870	0.130	0.000
S80-S89 Injuries to the knee and lower leg	0.869	0.131	0.000
S20-S29 Injuries to the thorax	0.868	0.132	0.000
M70-M79 Other soft tissue disorders	0.865	0.135	0.000
M89.9 Disorder of bone, unspecified	0.865	0.135	0.000
M54.50 Low back pain (Multiple sites in spine)	0.865	0.135	0.000
M80 Osteoporosis with pathological fracture	0.865	0.135	0.000
M45 Ankylosing spondylitis	0.863	0.137	0.000
B15-B19 Viral hepatitis	0.863	0.137	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.861	0.139	0.000
Y40 Systemic antibiotics	0.861	0.139	0.000
M54.57 Low back pain (Lumbosacral region)	0.858	0.142	0.000
V80-V89 Other land transport accidents	0.856	0.144	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.856	0.144	0.000
T17.2 Foreign body in pharynx	0.854	0.146	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.851	0.149	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.850	0.150	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.849	0.151	0.000
Chapter XXII Codes for special purposes	0.847	0.153	0.000
M84 Disorders of continuity of bone	0.840	0.160	0.000
T92.0 Sequelae of open wound of upper limb	0.837	0.163	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.835	0.165	0.000
T79-T79 Certain early complications of trauma	0.834	0.166	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.833	0.167	0.000
M54.4 Lumbago with sciatica	0.831	0.169	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.831	0.169	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.825	0.175	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.821	0.179	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.821	0.179	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.819	0.181	0.000
M81 Osteoporosis without pathological fracture	0.818	0.182	0.000
W22 Striking against or struck by other objects	0.818	0.182	0.000
M87 Osteonecrosis	0.813	0.187	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.812	0.188	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.809	0.191	0.000
E20-E35 Disorders of other endocrine glands	0.804	0.196	0.000
S10-S19 Injuries to the neck	0.803	0.197	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.802	0.198	0.000
T18 Foreign body in alimentary tract	0.800	0.200	0.000
M65-M68 Disorders of synovium and tendon	0.798	0.202	0.000
W19 Unspecified fall	0.796	0.204	0.000
B95-B98 Bacterial, viral and other infectious agents	0.791	0.209	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.790	0.210	0.000
S50-S59 Injuries to the elbow and forearm	0.790	0.210	0.000
M75 Shoulder lesions	0.789	0.211	0.000
M54.22 Cervicalgia (Cervical region)	0.789	0.211	0.000
X20-X29 Contact with venomous animals and plants	0.787	0.213	0.000
Q00-Q07 Congenital malformations of the nervous system	0.786	0.214	0.000
X50-X57 Overexertion, travel and privation	0.784	0.216	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.782	0.218	0.000
A02 Other Salmonella infections	0.780	0.220	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.780	0.220	0.000
M86 Osteomyelitis	0.779	0.221	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.778	0.222	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.775	0.225	0.000
Y40.8 Other systemic antibiotics	0.774	0.226	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.774	0.226	0.000
T43.6 Psychostimulants with abuse potential	0.771	0.229	0.000
S82 Fracture of lower leg, including ankle	0.770	0.230	0.000
M83 Adult osteomalacia	0.767	0.233	0.000
S36 Injury of intra-abdominal organs	0.767	0.233	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.767	0.233	0.000
M91-M94 Chondropathies	0.765	0.235	0.000
B50-B64 Protozoal diseases	0.764	0.236	0.000
B17 Other acute viral hepatitis	0.762	0.238	0.000
S90-S99 Injuries to the ankle and foot	0.760	0.240	0.000
S79 Other and unspecified injuries of hip and thigh	0.759	0.241	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.758	0.242	0.000
Q50-Q56 Congenital malformations of genital organs	0.758	0.242	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.755	0.245	0.000
A08 Viral and other specified intestinal infections	0.755	0.245	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.755	0.245	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.755	0.245	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.754	0.245	0.000
A07 Other protozoal intestinal diseases	0.754	0.246	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.754	0.246	0.000
Y52 Agents primarily affecting the cardiovascular system	0.752	0.248	0.000
V01-V09 Pedestrian injured in transport accident	0.751	0.249	0.000
T51 Toxic effect of alcohol	0.748	0.252	0.000
W50-W64 Exposure to animate mechanical forces	0.748	0.252	0.000
V40-V49 Car occupant injured in transport accident	0.747	0.253	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.747	0.253	0.000
M60-M63 Disorders of muscles	0.746	0.253	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.745	0.255	0.000
S20 Superficial injury of thorax	0.744	0.256	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.742	0.257	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.741	0.258	0.000
Chapter VI Diseases of the nervous system	0.741	0.259	0.000
M54.37 Sciatica (Lumbosacral region)	0.741	0.259	0.000
M40-M43 Deforming dorsopathies	0.739	0.261	0.000
M85 Other disorders of bone density and structure	0.737	0.263	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.736	0.264	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.735	0.265	0.000
Y48 Anaesthetics and therapeutic gases	0.735	0.265	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.734	0.266	0.000
M89.5 Osteolysis	0.732	0.268	0.000
S81 Open wound of lower leg	0.732	0.268	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.729	0.271	0.000
Q80-Q89 Other congenital malformations	0.729	0.271	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.728	0.272	0.000
Y85 Sequelae of transport accidents	0.727	0.272	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.726	0.274	0.000
M65 Synovitis and tenosynovitis	0.725	0.275	0.000
W19.9 Unspecified place	0.724	0.276	0.000
T00-T07 Injuries involving multiple body regions	0.723	0.277	0.000
G35 Multiple sclerosis	0.723	0.277	0.000
M84.0 Malunion of fracture	0.722	0.278	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.722	0.278	0.000
Y88 Sequelae of surgical and medical care as external cause	0.722	0.278	0.000
T42.1 Iminostilbenes	0.720	0.280	0.000
M89.0 Algoneurodystrophy	0.720	0.280	0.000
M54.39 Sciatica (Site unspecified)	0.719	0.281	0.000
M54.55 Low back pain (Thoracolumbar region)	0.718	0.282	0.000
W22.9 Unspecified place	0.718	0.282	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.718	0.282	0.000
T91.3 Sequelae of injury of spinal cord	0.718	0.282	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
W07 Fall involving chair	0.717	0.283	0.000
Y35-Y36 Legal intervention and operations of war	0.716	0.284	0.000
Y10-Y34 Event of undetermined intent	0.716	0.284	0.000
Y00-Y09 Assault	0.716	0.284	0.000
X85-X99 Assault	0.716	0.284	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.716	0.284	0.000
X30-X39 Exposure to forces of nature	0.716	0.284	0.000
X10-X19 Contact with heat and hot substances	0.716	0.284	0.000
X00-X09 Exposure to smoke, fire and flames	0.716	0.284	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284	0.000
W75-W84 Other accidental threats to breathing	0.716	0.284	0.000
W65-W74 Accidental drowning and submersion	0.716	0.284	0.000
V98-V99 Other and unspecified transport accidents	0.716	0.284	0.000
V95-V97 Air and space transport accidents	0.716	0.284	0.000
V90-V94 Water transport accidents	0.716	0.284	0.000
V70-V79 Bus occupant injured in transport accident	0.716	0.284	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284	0.000
S72.1 Pertrochanteric fracture	0.716	0.284	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284	0.000
T36 Poisoning by systemic antibiotics	0.716	0.284	0.000
S60-S69 Injuries to the wrist and hand	0.716	0.284	0.000
T93.0 Sequelae of open wound of lower limb	0.716	0.284	0.000
T95 Sequelae of burns, corrosions and frostbite	0.715	0.285	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.715	0.285	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.715	0.285	0.000
T98 Sequelae of other and unspecified effects of external causes	0.715	0.285	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.714	0.285	0.000
M54.8 Other dorsalgia	0.714	0.286	0.000
M54.0 Panniculitis affecting regions of neck and back	0.714	0.286	0.000
M00-M03 Infectious arthropathies	0.713	0.287	0.000
B18 Chronic viral hepatitis	0.712	0.288	0.000
Y40.7 Antifungal antibiotics, systemically used	0.712	0.288	0.000
W20 Struck by thrown, projected or falling object	0.711	0.289	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.711	0.289	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.711	0.289	0.000
S27 Injury of other and unspecified intrathoracic organs	0.710	0.290	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.710	0.290	0.000
S78 Traumatic amputation of hip and thigh	0.709	0.291	0.000
S77 Crushing injury of hip and thigh	0.709	0.291	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.709	0.291	0.000
S75 Injury of blood vessels at hip and thigh level	0.709	0.291	0.000
S74 Injury of nerves at hip and thigh level	0.709	0.291	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.709	0.291	0.000
S71 Open wound of hip and thigh	0.709	0.291	0.000
M89.8 Other specified disorders of bone	0.709	0.291	0.000
W19.2 School, other institution and public administrative area	0.709	0.291	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.709	0.291	0.000
Y54.5 Other diuretics	0.709	0.291	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.707	0.293	0.000
S21 Open wound of thorax	0.706	0.294	0.000
M87.9 Osteonecrosis, unspecified	0.706	0.294	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.706	0.294	0.000
S82.2 Fracture of shaft of tibia	0.704	0.296	0.000
S72.9 Fracture of femur, part unspecified	0.702	0.297	0.000
S72.8 Fractures of other parts of femur	0.702	0.297	0.000
S72.7 Multiple fractures of femur	0.702	0.297	0.000
S70 Superficial injury of hip and thigh	0.702	0.298	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.702	0.298	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.702	0.298	0.000
Y59 Other and unspecified vaccines and biological substances	0.702	0.298	0.000
Y58 Bacterial vaccines	0.702	0.298	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.702	0.298	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.702	0.298	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.702	0.298	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.702	0.298	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.702	0.298	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.702	0.298	0.000
M48 Other spondylopathies	0.701	0.299	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.700	0.300	0.000
S72.01 Fracture of neck of femur (open)	0.700	0.300	0.000
M54.54 Low back pain-Thoracic	0.699	0.301	0.000
M54.53 Low back pain-Cervicothoracic	0.699	0.301	0.000
M54.52 Low back pain-Cervical	0.699	0.301	0.000
M54.51 Low back pain-Occipit-atl-axl	0.699	0.301	0.000
W21 Striking against or struck by sports equipment	0.699	0.301	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.699	0.301	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.698	0.302	0.000
M82 Osteoporosis in diseases classified elsewhere	0.698	0.302	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.697	0.302	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.697	0.302	0.000
T91.1 Sequelae of fracture of spine	0.696	0.304	0.000
Y89 Sequelae of other external causes	0.695	0.305	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.695	0.305	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.695	0.305	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.694	0.306	0.000
T18.1 Foreign body in oesophagus	0.692	0.308	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.692	0.308	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.692	0.308	0.000
A75-A79 Rickettsioses	0.692	0.308	0.000
A70-A74 Other diseases caused by chlamydiae	0.692	0.308	0.000
A65-A69 Other spirochaetal diseases	0.692	0.308	0.000
A20-A28 Certain zoonotic bacterial diseases	0.692	0.308	0.000
A15-A19 Tuberculosis	0.692	0.308	0.000
B65-B83 Helminthiases	0.691	0.309	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.691	0.309	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.691	0.309	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.691	0.309	0.000
T42.3 Barbiturates	0.691	0.309	0.000
T42.2 Succinimides and oxazolidinediones	0.691	0.309	0.000
T42.0 Hydantoin derivatives	0.691	0.309	0.000
E24 Cushing's syndrome	0.691	0.309	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.690	0.310	0.000
T43.9 Psychotropic drug, unspecified	0.690	0.310	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.690	0.310	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.690	0.310	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.690	0.310	0.000
M75.9 Shoulder lesion, unspecified	0.689	0.311	0.000
B17.1 Acute hepatitis C	0.689	0.311	0.000
M54.1 Radiculopathy	0.688	0.312	0.000
M70.6 Trochanteric bursitis	0.687	0.313	0.000
M54.29 Cervicalgia-Site unspe	0.685	0.315	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.684	0.316	0.000
M49 Spondylopathies in diseases classified elsewhere	0.683	0.317	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.682	0.318	0.000
T19 Foreign body in genito-urinary tract	0.682	0.318	0.000
T15 Foreign body on external eye	0.682	0.318	0.000
T16 Foreign body in ear	0.682	0.318	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.682	0.318	0.000
A06 Amoebiasis	0.680	0.319	0.000
A05 Other bacterial foodborne intoxications	0.680	0.319	0.000
A03 Shigellosis	0.680	0.319	0.000
A01 Typhoid and paratyphoid fevers	0.680	0.319	0.000
A00 Cholera	0.680	0.319	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.680	0.320	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.680	0.320	0.000
Y42.9 Other and unspecified hormone antagonists	0.679	0.321	0.000
Y42.4 Oral contraceptives	0.679	0.321	0.000
Y42.2 Antithyroid drugs	0.679	0.321	0.000
Y42.1 Thyroid hormones and substitutes	0.679	0.321	0.000
T51.0 Ethanol	0.679	0.321	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.679	0.321	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.677	0.323	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.677	0.323	0.000
D60-D64 Aplastic and other anaemias	0.676	0.324	0.000
T14 Injury of unspecified body region	0.676	0.324	0.000
W08 Fall involving other furniture	0.676	0.324	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.676	0.324	0.000
M54.36 Sciatica (Lumbar region)	0.675	0.325	0.000
T11 Other injuries of upper limb, level unspecified	0.675	0.325	0.000
M53 Other dorsopathies, not elsewhere classified	0.675	0.325	0.000
X60-X84 Intentional self-harm	0.674	0.326	0.000
M75.1 Rotator cuff syndrome	0.674	0.326	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.673	0.327	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.672	0.328	0.000
Q35-Q37 Cleft lip and cleft palate	0.672	0.328	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.672	0.328	0.000
S82.0 Fracture of patella	0.672	0.328	0.000
S00-S09 Injuries to the head	0.672	0.328	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.671	0.329	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.671	0.329	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.671	0.329	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.671	0.329	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.671	0.329	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.671	0.329	0.000
S37 Injury of urinary and pelvic organs	0.670	0.330	0.000
M81.4 Drug-induced osteoporosis	0.670	0.330	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.669	0.331	0.000
M88 Paget's disease of bone [osteitis deformans]	0.669	0.331	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.668	0.332	0.000
T56 Toxic effect of metals	0.668	0.332	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.667	0.333	0.000
M75.2 Bicipital tendinitis	0.667	0.333	0.000
M51 Other intervertebral disk disorders	0.666	0.333	0.001
S36.1 Injury of liver or gallbladder	0.666	0.334	0.000
W18 Other fall on same level	0.664	0.336	0.000
M89.6 Osteopathy after poliomyelitis	0.664	0.336	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.664	0.336	0.000
M89.3 Hypertrophy of bone	0.664	0.336	0.000
M89.2 Other disorders of bone development and growth	0.664	0.336	0.000
M89.1 Epiphyseal arrest	0.664	0.336	0.000
Y40.3 Macrolides	0.664	0.336	0.000
L60-L75 Disorders of skin appendages	0.664	0.336	0.000
A04 Other bacterial intestinal infections	0.663	0.337	0.000
D80-D89 Certain disorders involving the immune mechanism	0.663	0.337	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.662	0.338	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.662	0.338	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.662	0.338	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.662	0.338	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.662	0.338	0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.662	0.338	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.661	0.339	0.000
W17 Other fall from one level to another	0.661	0.339	0.000
M72 Fibroblastic disorders	0.659	0.341	0.000
A02.0 Salmonella gastro-enteritis	0.659	0.341	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.659	0.341	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.659	0.341	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.659	0.341	0.000
T93.1 Sequelae of fracture of femur	0.659	0.341	0.000
T90 Sequelae of injuries of head	0.659	0.341	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.658	0.342	0.000
V10-V19 Pedal cyclist injured in transport accident	0.658	0.342	0.000
T45.0 Antiallergic and antiemetic drugs	0.658	0.342	0.000
W46 Contact with hypodermic needle	0.657	0.343	0.000
W45 Foreign body or object entering through skin	0.657	0.343	0.000
W43 Exposure to vibration	0.657	0.343	0.000
W42 Exposure to noise	0.657	0.343	0.000
W41 Exposure to high-pressure jet	0.657	0.343	0.000
W40 Explosion of other materials	0.657	0.343	0.000
W39 Discharge of firework	0.657	0.343	0.000
W38 Explosion and rupture of other specified pressurised devices	0.657	0.343	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.657	0.343	0.000
W36 Explosion and rupture of gas cylinder	0.657	0.343	0.000
W35 Explosion and rupture of boiler	0.657	0.343	0.000
W34 Discharge from other and unspecified firearms	0.657	0.343	0.000
W33 Rifle, shotgun and larger firearm discharge	0.657	0.343	0.000
W32 Handgun discharge	0.657	0.343	0.000
W31 Contact with other and unspecified machinery	0.657	0.343	0.000
W30 Contact with agricultural machinery	0.657	0.343	0.000
W28 Contact with powered lawn mower	0.657	0.343	0.000
W27 Contact with nonpowered hand tool	0.657	0.343	0.000
W26 Contact with knife, sword or dagger	0.657	0.343	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.657	0.343	0.000
V20-V29 Motorcycle rider injured in transport accident	0.656	0.344	0.000
M46.8 Other specified inflammatory spondylopathies	0.655	0.345	0.000
M46.5 Other infective spondylopathies	0.655	0.345	0.000
M46.4 Discitis, unspecified	0.655	0.345	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.655	0.345	0.000
M46.2 Osteomyelitis of vertebra	0.655	0.345	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.655	0.345	0.000
M46.0 Spinal enthesopathy	0.655	0.345	0.000
W44 Foreign body entering into or through eye or natural orifice	0.655	0.345	0.000
M54.59 Low back pain (Site unspecified)	0.655	0.345	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.654	0.345	0.000
W22.5 Trade and service area	0.654	0.346	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.654	0.346	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.654	0.346	0.000
Y44 Agents primarily affecting blood constituents	0.653	0.346	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.653	0.347	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.652	0.348	0.000
S72.3 Fracture of shaft of femur	0.651	0.349	0.000
W29 Contact with other powered hand tools and household machinery	0.650	0.350	0.000
E26 Hyperaldosteronism	0.650	0.350	0.000
M75.5 Bursitis of shoulder	0.649	0.351	0.000
T79.6 Traumatic ischaemia of muscle	0.648	0.352	0.000
S12 Fracture of neck	0.646	0.354	0.000
W06 Fall involving bed	0.645	0.355	0.000
T13 Other injuries of lower limb, level unspecified	0.644	0.355	0.000
Q43 Other congenital malformations of intestine	0.644	0.356	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.643	0.357	0.000
S72.2 Subtrochanteric fracture	0.642	0.358	0.000
S82.3 Fracture of lower end of tibia	0.642	0.358	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.642	0.358	0.000
Q05 Spina bifida	0.642	0.358	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.642	0.358	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.642	0.358	0.000
W15 Fall from cliff	0.642	0.358	0.000
W14 Fall from tree	0.642	0.358	0.000
W12 Fall on and from scaffolding	0.642	0.358	0.000
W11 Fall on and from ladder	0.642	0.358	0.000
W09 Fall involving playground equipment	0.642	0.358	0.000
W05 Fall involving wheelchair	0.642	0.358	0.000
W04 Fall while being carried or supported by other persons	0.642	0.358	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.642	0.358	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.642	0.358	0.000
W00 Fall on same level involving ice and snow	0.642	0.358	0.000
S89 Other and unspecified injuries of lower leg	0.641	0.359	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.639	0.361	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.639	0.361	0.000
T46.7 Peripheral vasodilators	0.639	0.361	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.639	0.361	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.639	0.361	0.000
T46.1 Calcium-channel blockers	0.639	0.361	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.639	0.361	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.638	0.362	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.638	0.362	0.000
S72.4 Fracture of lower end of femur	0.637	0.362	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.637	0.363	0.000
T17.5 Foreign body in bronchus	0.637	0.363	0.000
T17.4 Foreign body in trachea	0.637	0.363	0.000
T17.3 Foreign body in larynx	0.637	0.363	0.000
T17.1 Foreign body in nostril	0.637	0.363	0.000
T17.0 Foreign body in nasal sinus	0.637	0.363	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.636	0.364	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.636	0.364	0.000
M54.27 Cervicalgia-Lumbosacral	0.636	0.364	0.000
M54.26 Cervicalgia-Lumbar	0.636	0.364	0.000
M54.25 Cervicalgia-Thoracolumbar	0.636	0.364	0.000
M54.24 Cervicalgia-Thoracic	0.636	0.364	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.636	0.364	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.636	0.364	0.000
M54.20 Cervicalgia-Mult site	0.636	0.364	0.000
A80-A89 Viral infections of the central nervous system	0.635	0.365	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.635	0.365	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.635	0.365	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.635	0.365	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.635	0.365	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.635	0.365	0.000
X23 Contact with hornets, wasps and bees	0.635	0.365	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.634	0.365	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.634	0.365	0.000
M54.35 Sciatica (Thoracolumbar region)	0.634	0.365	0.000
M54.34 Sciatica-Thoracic	0.634	0.365	0.000
M54.33 Sciatica-Cervicothoracic	0.634	0.365	0.000
M54.32 Sciatica-Cervical	0.634	0.365	0.000
M54.31 Sciatica-Occipit-atl-axl	0.634	0.365	0.000
M54.30 Sciatica (Multiple sites in spine)	0.634	0.365	0.000
X50 Overexertion and strenuous or repetitive movements	0.634	0.366	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.634	0.366	0.000
E28 Ovarian dysfunction	0.633	0.366	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.633	0.367	0.000
M51.2 Other specified intervertebral disk displacement	0.633	0.367	0.000
T45.5 Anticoagulants	0.632	0.367	0.000
E23 Hypofunction and other disorders of pituitary gland	0.632	0.368	0.000
M54.6 Pain in thoracic spine	0.632	0.368	0.000
E20 Hypoparathyroidism	0.632	0.368	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.632	0.368	0.000
S36.0 Injury of spleen	0.632	0.368	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.632	0.368	0.000
T40.6 Other and unspecified narcotics	0.631	0.369	0.000
S82.20 Fracture of shaft of tibia (closed)	0.630	0.370	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.630	0.370	0.000
M81.9 Osteoporosis, unspecified	0.629	0.371	0.000
S54 Injury of nerves at forearm level	0.629	0.371	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.628	0.372	0.000
E27 Other disorders of adrenal gland	0.628	0.372	0.000
S27.2 Traumatic heamopneumothorax	0.627	0.373	0.000
S51 Open wound of forearm	0.627	0.373	0.000
S31 Open wound of abdomen, lower back and pelvis	0.627	0.373	0.000
S88 Traumatic amputation of lower leg	0.623	0.377	0.000
S87 Crushing injury of lower leg	0.623	0.377	0.000
S85 Injury of blood vessels at lower leg level	0.623	0.377	0.000
S84 Injury of nerves at lower leg level	0.623	0.377	0.000
S20.2 Contusion of thorax	0.623	0.377	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.623	0.377	0.000
S26 Injury of heart	0.623	0.377	0.000
S25 Injury of blood vessels of thorax	0.623	0.377	0.000
S24 Injury of nerves and spinal cord at thorax level	0.623	0.377	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.623	0.377	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations