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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11226914
log Bayes Factor = 32.1781
Chromosome 11   position 105,941,504  (GRCh37) Explore rs11226914 on Ensembl!
Variant rs11226914 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
I83 Varicose veins of lower extremities
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
T81 Complications of procedures, not elsewhere classified
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.999 0.001 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter II Neoplasms
0.997 0.003 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.995 0.005 0.000
C44 Other malignant neoplasms of skin
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.990 0.010 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.980 0.020 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.979 0.021 0.000
S00-S09 Injuries to the head
0.978 0.022 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.978 0.022 0.000
Chapter I Certain infectious and parasitic diseases
0.977 0.023 0.000
I20-I25 Ischaemic heart diseases
0.977 0.023 0.000
Y83.8 Other surgical procedures
0.974 0.026 0.000
E86 Volume depletion
0.972 0.028 0.000
R59 Enlarged lymph nodes
0.970 0.030 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.970 0.030 0.000
E11 Non-insulin-dependent diabetes mellitus
0.968 0.032 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.965 0.035 0.000
B95-B98 Bacterial, viral and other infectious agents
0.964 0.036 0.000
Chapter XXI Factors influencing health status and contact with health services
0.963 0.037 0.000
Chapter XI Diseases of the digestive system
0.961 0.039 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.960 0.040 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.959 0.041 0.000
C44.4 Skin of scalp and neck
0.958 0.042 0.000
R59.0 Localised enlarged lymph nodes
0.955 0.045 0.000
R69 Unknown and unspecified causes of morbidity
0.952 0.048 0.000
M20-M25 Other joint disorders
0.952 0.048 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.949 0.051 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.948 0.052 0.000
Y43 Primarily systemic agents
0.942 0.058 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.942 0.058 0.000
M25 Other joint disorders, not elsewhere classified
0.941 0.059 0.000
C15-C26 Malignant neoplasms of digestive organs
0.941 0.059 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.940 0.060 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.935 0.065 0.000
M25.5 Pain in joint
0.934 0.066 0.000
I30-I52 Other forms of heart disease
0.934 0.066 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.933 0.067 0.000
S80-S89 Injuries to the knee and lower leg
0.933 0.067 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.929 0.071 0.000
M25.56 Pain in joint (Lower leg)
0.929 0.071 0.000
G35 Multiple sclerosis
0.926 0.074 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.926 0.074 0.000
I25 Chronic ischaemic heart disease
0.922 0.078 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.920 0.080 0.000
Chapter VII Diseases of the eye and adnexa
0.917 0.083 0.000
G90-G99 Other disorders of the nervous system
0.916 0.084 0.000
I20 Angina pectoris
0.915 0.085 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.913 0.087 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.912 0.088 0.000
E14 Unspecified diabetes mellitus
0.912 0.088 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.912 0.088 0.000
I45 Other conduction disorders
0.911 0.089 0.000
I78 Diseases of capillaries
0.908 0.092 0.000
Y43.3 Other antineoplastic drugs
0.907 0.093 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.904 0.096 0.000
F30-F39 Mood [affective] disorders
0.904 0.096 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.903 0.097 0.000
K02 Dental caries
0.902 0.098 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.901 0.099 0.000
R21 Rash and other nonspecific skin eruption
0.901 0.099 0.000
R51 Headache
0.899 0.101 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.892 0.107 0.000
E11.4 With neurological complications
0.892 0.108 0.000
I71 Aortic aneurysm and dissection
0.892 0.108 0.000
E20-E35 Disorders of other endocrine glands
0.890 0.110 0.000
E11.3 With ophthalmic complications
0.888 0.112 0.000
R60 Oedema, not elsewhere classified
0.888 0.112 0.000
C44.1 Skin of eyelid, including canthus
0.888 0.112 0.000
S02 Fracture of skull and facial bones
0.888 0.112 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.887 0.113 0.000
C44.5 Skin of trunk
0.886 0.114 0.000
I73 Other peripheral vascular diseases
0.881 0.119 0.000
E10 Insulin-dependent diabetes mellitus
0.876 0.124 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.874 0.126 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.872 0.128 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.871 0.129 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.871 0.129 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.870 0.130 0.000
I87 Other disorders of veins
0.868 0.132 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.868 0.132 0.000
I45.1 Other and unspecified right bundle-branch block
0.866 0.134 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.866 0.134 0.000
E14.9 Without complications
0.865 0.135 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.863 0.137 0.000
K01 Embedded and impacted teeth
0.863 0.137 0.000
S00 Superficial injury of head
0.861 0.139 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.858 0.142 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.858 0.142 0.000
R53 Malaise and fatigue
0.856 0.144 0.000
I77 Other disorders of arteries and arterioles
0.855 0.145 0.000
R20 Disturbances of skin sensation
0.854 0.146 0.000
W00-W19 Falls
0.854 0.146 0.000
C44.3 Skin of other and unspecified parts of face
0.854 0.146 0.000
R79 Other abnormal findings of blood chemistry
0.853 0.147 0.000
Chapter VIII Diseases of the ear and mastoid process
0.852 0.148 0.000
T42.4 Benzodiazepines
0.850 0.150 0.000
S09 Other and unspecified injuries of head
0.849 0.151 0.000
S81 Open wound of lower leg
0.849 0.151 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.849 0.151 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.848 0.152 0.000
I78.1 Naevus, nonneoplastic
0.846 0.154 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.845 0.155 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.842 0.158 0.000
I46 Cardiac arrest
0.840 0.160 0.000
M50-M54 Other dorsopathies
0.838 0.162 0.000
G56 Mononeuropathies of upper limb
0.837 0.163 0.000
R60.0 Localised oedema
0.834 0.166 0.000
G93 Other disorders of brain
0.833 0.167 0.000
K02.9 Dental caries, unspecified
0.833 0.167 0.000
I20.0 Unstable angina
0.829 0.171 0.000
I27 Other pulmonary heart diseases
0.828 0.172 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.826 0.174 0.000
G30-G32 Other degenerative diseases of the nervous system
0.825 0.175 0.000
F43 Reaction to severe stress, and adjustment disorders
0.825 0.175 0.000
G62 Other polyneuropathies
0.824 0.176 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.821 0.179 0.000
D00-D09 In situ neoplasms
0.820 0.180 0.000
F40 Phobic anxiety disorders
0.820 0.180 0.000
K08 Other disorders of teeth and supporting structures
0.819 0.181 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.819 0.181 0.000
M25.57 Pain in joint (Ankle and foot)
0.819 0.181 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.819 0.181 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.816 0.184 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.815 0.185 0.000
Y40 Systemic antibiotics
0.814 0.186 0.000
S02.2 Fracture of nasal bones
0.814 0.186 0.000
L60-L75 Disorders of skin appendages
0.814 0.186 0.000
K14 Diseases of tongue
0.813 0.187 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.812 0.188 0.000
I74 Arterial embolism and thrombosis
0.811 0.189 0.000
B35-B49 Mycoses
0.811 0.189 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.811 0.189 0.000
C20 Malignant neoplasm of rectum
0.810 0.190 0.000
H53-H54 Visual disturbances and blindness
0.809 0.191 0.000
I73.9 Peripheral vascular disease, unspecified
0.809 0.191 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.809 0.191 0.000
I51 Complications and ill-defined descriptions of heart disease
0.809 0.191 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.808 0.192 0.000
T66-T78 Other and unspecified effects of external causes
0.807 0.193 0.000
F03 Unspecified dementia
0.806 0.194 0.000
I80 Phlebitis and thrombophlebitis
0.805 0.195 0.000
F00 Dementia in Alzheimer's disease
0.804 0.196 0.000
E85 Amyloidosis
0.804 0.196 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.804 0.196 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.804 0.196 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.804 0.196 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.803 0.197 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.802 0.198 0.000
K11 Diseases of salivary glands
0.801 0.199 0.000
I88 Nonspecific lymphadenitis
0.800 0.200 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.798 0.202 0.000
I50 Heart failure
0.797 0.203 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.796 0.204 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.796 0.204 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.795 0.205 0.000
Chapter XXII Codes for special purposes
0.795 0.205 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.795 0.205 0.000
G56.0 Carpal tunnel syndrome
0.795 0.205 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.794 0.205 0.000
R40 Somnolence, stupor and coma
0.793 0.207 0.000
I25.2 Old myocardial infarction
0.793 0.207 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.793 0.207 0.000
Z46 Fitting and adjustment of other devices
0.793 0.207 0.000
K01.1 Impacted teeth
0.793 0.207 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.792 0.208 0.000
C44.7 Skin of lower limb, including hip
0.791 0.209 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.790 0.210 0.000
Z45 Adjustment and management of implanted device
0.789 0.211 0.000
Y83.3 Surgical operation with formation of external stoma
0.788 0.212 0.000
Z53.0 Procedure not carried out because of contraindication
0.787 0.213 0.000
R52 Pain, not elsewhere classified
0.786 0.214 0.000
F41 Other anxiety disorders
0.786 0.214 0.000
R63 Symptoms and signs concerning food and fluid intake
0.786 0.214 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.785 0.215 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.785 0.215 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.785 0.215 0.000
F33 Recurrent depressive disorder
0.784 0.216 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.784 0.216 0.000
M21 Other acquired deformities of limbs
0.782 0.217 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.782 0.218 0.000
R58 Haemorrhage, not elsewhere classified
0.782 0.218 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.782 0.218 0.000
M65 Synovitis and tenosynovitis
0.781 0.219 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.779 0.221 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.777 0.223 0.000
S81.8 Open wound of other parts of lower leg
0.777 0.223 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.776 0.224 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.776 0.224 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.773 0.227 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.773 0.227 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.771 0.229 0.000
Y83.5 Amputation of limb(s)
0.771 0.229 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.771 0.229 0.000
I45.6 Preexcitation syndrome
0.771 0.229 0.000
Y52 Agents primarily affecting the cardiovascular system
0.770 0.230 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.770 0.230 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.769 0.231 0.000
K04 Diseases of pulp and periapical tissues
0.769 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.769 0.231 0.000
S00.0 Superficial injury of scalp
0.768 0.232 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.768 0.232 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.768 0.232 0.000
C44.0 Skin of lip
0.767 0.232 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.767 0.233 0.000
L08 Other local infections of skin and subcutaneous tissue
0.767 0.233 0.000
Y57 Other and unspecified drugs and medicaments
0.767 0.233 0.000
I22 Subsequent myocardial infarction
0.765 0.234 0.000
K09 Cysts of oral region, not elsewhere classified
0.765 0.235 0.000
E83 Disorders of mineral metabolism
0.765 0.235 0.000
W50-W64 Exposure to animate mechanical forces
0.765 0.235 0.000
L50-L54 Urticaria and erythema
0.763 0.237 0.000
X50-X57 Overexertion, travel and privation
0.762 0.238 0.000
S02.20 Fracture of nasal bones (closed)
0.761 0.239 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.761 0.239 0.000
Z22 Carrier of infectious disease
0.761 0.239 0.000
T92 Sequelae of injuries of upper limb
0.761 0.239 0.000
M40-M43 Deforming dorsopathies
0.760 0.240 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.760 0.240 0.000
S01 Open wound of head
0.760 0.240 0.000
R76 Other abnormal immunological findings in serum
0.759 0.241 0.000
Y83.9 Surgical procedure, unspecified
0.759 0.241 0.000
G91 Hydrocephalus
0.757 0.243 0.000
S09.9 Unspecified injury of head
0.757 0.243 0.000
M31 Other necrotising vasculopathies
0.756 0.244 0.000
W19 Unspecified fall
0.755 0.245 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.755 0.245 0.000
C16 Malignant neoplasm of stomach
0.754 0.246 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.754 0.246 0.000
I82 Other venous embolism and thrombosis
0.752 0.247 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.752 0.248 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.751 0.249 0.000
Z41 Procedures for purposes other than remedying health state
0.751 0.249 0.000
F60-F69 Disorders of adult personality and behaviour
0.750 0.250 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.750 0.250 0.000
C43 Malignant melanoma of skin
0.749 0.251 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.749 0.251 0.000
H60-H62 Diseases of external ear
0.746 0.254 0.000
K02.8 Other dental caries
0.746 0.254 0.000
Z42 Follow-up care involving plastic surgery
0.746 0.254 0.000
F99-F99 Unspecified mental disorder
0.746 0.254 0.000
S10-S19 Injuries to the neck
0.745 0.255 0.000
K12 Stomatitis and related lesions
0.745 0.255 0.000
T93 Sequelae of injuries of lower limb
0.744 0.256 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.744 0.256 0.000
I33 Acute and subacute endocarditis
0.744 0.256 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.743 0.257 0.000
A30-A49 Other bacterial diseases
0.741 0.259 0.000
I45.9 Conduction disorder, unspecified
0.740 0.260 0.000
M50 Cervical disk disorders
0.740 0.260 0.000
M25.4 Effusion of joint
0.740 0.260 0.000
I46.0 Cardiac arrest with successful resuscitation
0.740 0.260 0.000
M25.8 Other specified joint disorders
0.738 0.262 0.000
I50.0 Congestive heart failure
0.738 0.262 0.000
I20.9 Angina pectoris, unspecified
0.736 0.264 0.000
F43.2 Adjustment disorders
0.736 0.264 0.000
A80-A89 Viral infections of the central nervous system
0.736 0.264 0.000
H10-H13 Disorders of conjunctiva
0.735 0.265 0.000
L60 Nail disorders
0.733 0.266 0.000
I77.1 Stricture of artery
0.733 0.267 0.000
M60-M63 Disorders of muscles
0.733 0.267 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.732 0.268 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.732 0.268 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.732 0.268 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.731 0.269 0.000
K90-K93 Other diseases of the digestive system
0.730 0.270 0.000
E24 Cushing's syndrome
0.730 0.270 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.730 0.270 0.000
F32 Depressive episode
0.729 0.271 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.728 0.272 0.000
F40.2 Specific (isolated) phobias
0.728 0.272 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.727 0.272 0.000
I51.7 Cardiomegaly
0.727 0.273 0.000
Z53.9 Procedure not carried out, unspecified reason
0.727 0.273 0.000
R22.1 Localised swelling, mass and lump, neck
0.726 0.274 0.000
R41.0 Disorientation, unspecified
0.726 0.274 0.000
C44.6 Skin of upper limb, including shoulder
0.726 0.274 0.000
I87.8 Other specified disorders of veins
0.726 0.274 0.000
E10.3 With ophthalmic complications
0.726 0.274 0.000
G62.9 Polyneuropathy, unspecified
0.726 0.274 0.000
I20.8 Other forms of angina pectoris
0.726 0.274 0.000
F01 Vascular dementia
0.725 0.274 0.000
Z43 Attention to artificial openings
0.725 0.275 0.000
I27.2 Other secondary pulmonary hypertension
0.724 0.276 0.000
C21 Malignant neoplasm of anus and anal canal
0.724 0.276 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.724 0.276 0.000
G93.4 Encephalopathy, unspecified
0.723 0.277 0.000
I05-I09 Chronic rheumatic heart diseases
0.722 0.278 0.000
Y44 Agents primarily affecting blood constituents
0.722 0.278 0.000
G37 Other demyelinating diseases of central nervous system
0.722 0.278 0.000
H55-H59 Other disorders of eye and adnexa
0.721 0.279 0.000
R45 Symptoms and signs involving emotional state
0.721 0.279 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.721 0.279 0.000
R57 Shock, not elsewhere classified
0.720 0.280 0.000
D03 Melanoma in situ
0.719 0.280 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.717 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I81 Portal vein thrombosis
0.717 0.283 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T81.9 Unspecified complication of procedure
0.717 0.283 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.717 0.283 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
H80-H83 Diseases of inner ear
0.717 0.283 0.000
Z52 Donors of organs and tissues
0.717 0.283 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.716 0.284 0.000
Y42.7 Androgens and anabolic congeners
0.716 0.284 0.000
R23 Other skin changes
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.285 0.000
R62 Lack of expected normal physiological development
0.715 0.285 0.000
R64 Cachexia
0.715 0.285 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.715 0.285 0.000
M25.54 Pain in joint (Hand)
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.714 0.285 0.000
M35 Other systemic involvement of connective tissue
0.714 0.286 0.000
K05 Gingivitis and periodontal diseases
0.714 0.286 0.000
G57 Mononeuropathies of lower limb
0.714 0.286 0.000
Z29 Need for other prophylactic measures
0.713 0.287 0.000
E13 Other specified diabetes mellitus
0.713 0.287 0.000
E12 Malnutrition-related diabetes mellitus
0.713 0.287 0.000
C44.8 Overlapping lesion of skin
0.713 0.287 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.713 0.287 0.000
I72 Other aneurysm
0.713 0.287 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.712 0.288 0.000
T79-T79 Certain early complications of trauma
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
S70-S79 Injuries to the hip and thigh
0.711 0.289 0.000
E11.9 Without complications
0.711 0.289 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.711 0.289 0.000
C44.2 Skin of ear and external auricular canal
0.710 0.289 0.000
D48.1 Connective and other soft tissue
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
S90-S99 Injuries to the ankle and foot
0.710 0.290 0.000
Y59 Other and unspecified vaccines and biological substances
0.709 0.290 0.000
Y58 Bacterial vaccines
0.709 0.290 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.709 0.290 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.709 0.290 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.709 0.290 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.709 0.290 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.709 0.290 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.709 0.290 0.000
Y48 Anaesthetics and therapeutic gases
0.709 0.290 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.709 0.290 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.709 0.290 0.000
S00.8 Superficial injury of other parts of head
0.709 0.291 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.709 0.291 0.000
T91 Sequelae of injuries of neck and trunk
0.708 0.292 0.000
R59.9 Enlarged lymph nodes, unspecified
0.708 0.292 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.708 0.292 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.708 0.292 0.000
I86 Varicose veins of other sites
0.707 0.293 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.705 0.294 0.000
E10.9 Without complications
0.705 0.295 0.000
I27.0 Primary pulmonary hypertension
0.705 0.295 0.000
E11.5 With peripheral circulatory complications
0.705 0.295 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E79 Disorders of purine and pyrimidine metabolism
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
E73 Lactose intolerance
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
R25 Abnormal involuntary movements
0.704 0.296 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.704 0.296 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.704 0.296 0.000
R73 Elevated blood glucose level
0.704 0.296 0.000
L10-L14 Bullous disorders
0.703 0.297 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.702 0.298 0.000
T31 Burns classified according to extent of body surface involved
0.702 0.298 0.000
M34 Systemic sclerosis
0.701 0.298 0.000
S08 Traumatic amputation of part of head
0.701 0.298 0.000
S07 Crushing injury of head
0.701 0.298 0.000
S05 Injury of eye and orbit
0.701 0.298 0.000
S04 Injury of cranial nerves
0.701 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.298 0.000
Y83.0 Surgical operation with transplant of whole organ
0.701 0.298 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.701 0.299 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
I23 Certain current complications following acute myocardial infarction
0.700 0.300 0.000
G58 Other mononeuropathies
0.699 0.300 0.000
K50-K52 Noninfective enteritis and colitis
0.699 0.301 0.000
E11.2 With renal complications
0.699 0.301 0.000
E28 Ovarian dysfunction
0.699 0.301 0.000
F33.9 Recurrent depressive disorder, unspecified
0.698 0.302 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.696 0.304 0.000
F31 Bipolar affective disorder
0.696 0.304 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.696 0.304 0.000
M91-M94 Chondropathies
0.695 0.304 0.000
M00-M03 Infectious arthropathies
0.695 0.304 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.696 0.304 0.000
F25 Schizoaffective disorders
0.695 0.305 0.000
I70 Atherosclerosis
0.694 0.306 0.000
M67 Other disorders of synovium and tendon
0.694 0.306 0.000
E11.8 With unspecified complications
0.694 0.306 0.000
E11.7 With multiple complications
0.694 0.306 0.000
E11.6 With other specified complications
0.694 0.306 0.000
E11.1 With ketoacidosis
0.694 0.306 0.000
E11.0 With coma
0.694 0.306 0.000
K08.3 Retained dental root
0.694 0.306 0.000
M24 Other specific joint derangements
0.693 0.306 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.692 0.308 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.692 0.308 0.000
F20 Schizophrenia
0.691 0.309 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.690 0.310 0.000
I30 Acute pericarditis
0.690 0.310 0.000
F45 Somatoform disorders
0.689 0.311 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.689 0.311 0.000
K03 Other diseases of hard tissues of teeth
0.689 0.311 0.000
K00 Disorders of tooth development and eruption
0.689 0.311 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.688 0.312 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.687 0.313 0.000
G36 Other acute disseminated demyelination
0.687 0.313 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.687 0.313 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.687 0.313 0.000
M86-M90 Other osteopathies
0.687 0.313 0.000
Z63 Other problems related to primary support group, including family circumstances
0.687 0.313 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.686 0.314 0.000
L57.0 Actinic keratosis
0.686 0.314 0.000
T43.2 Other and unspecified antidepressants
0.685 0.315 0.000
H53 Visual disturbances
0.685 0.315 0.000
F41.2 Mixed anxiety and depressive disorder
0.685 0.315 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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