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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12616962
log Bayes Factor = 15.3337
Chromosome 2   position 155,628,974  (GRCh37) Explore rs12616962 on Ensembl!
Variant rs12616962 is part of Cluster X0170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.996 0.004 0.000
W00-W19 Falls
0.995 0.005 0.000
S00 Superficial injury of head
0.992 0.008 0.000
S02 Fracture of skull and facial bones
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
W19 Unspecified fall
0.989 0.011 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.986 0.014 0.000
W19.9 Unspecified place
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.978 0.022 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.977 0.023 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.973 0.027 0.000
H02 Other disorders of eyelid
0.972 0.028 0.000
I60-I69 Cerebrovascular diseases
0.971 0.029 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
S60-S69 Injuries to the wrist and hand
0.965 0.035 0.000
H40-H42 Glaucoma
0.961 0.039 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.959 0.041 0.000
G81 Hemiplegia
0.958 0.042 0.000
I85 Oesophageal varices
0.954 0.046 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.954 0.046 0.000
K70-K77 Diseases of liver
0.948 0.052 0.000
Chapter XI Diseases of the digestive system
0.948 0.052 0.000
G81.9 Hemiplegia, unspecified
0.944 0.056 0.000
I85.9 Oesophageal varices without bleeding
0.941 0.059 0.000
I30-I52 Other forms of heart disease
0.935 0.065 0.000
G20-G26 Extrapyramidal and movement disorders
0.935 0.065 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.935 0.065 0.000
H40 Glaucoma
0.934 0.066 0.000
G90-G99 Other disorders of the nervous system
0.933 0.067 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.933 0.067 0.000
I69 Sequelae of cerebrovascular disease
0.933 0.067 0.000
K76 Other diseases of liver
0.933 0.067 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.931 0.069 0.000
S00.8 Superficial injury of other parts of head
0.922 0.078 0.000
I34 Nonrheumatic mitral valve disorders
0.919 0.081 0.000
M23 Internal derangement of knee
0.919 0.081 0.000
S00.9 Superficial injury of head, part unspecified
0.918 0.082 0.000
G57 Mononeuropathies of lower limb
0.917 0.083 0.000
H30-H36 Disorders of choroid and retina
0.916 0.084 0.000
M21 Other acquired deformities of limbs
0.910 0.090 0.000
H02.0 Entropion and trichiasis of eyelid
0.909 0.091 0.000
S02.1 Fracture of base of skull
0.908 0.092 0.000
K86 Other diseases of pancreas
0.904 0.096 0.000
W19.2 School, other institution and public administrative area
0.901 0.099 0.000
G57.6 Lesion of plantar nerve
0.899 0.101 0.000
M80-M85 Disorders of bone density and structure
0.899 0.101 0.000
G20 Parkinson's disease
0.898 0.102 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.894 0.106 0.000
I34.0 Mitral (valve) insufficiency
0.893 0.107 0.000
M23.3 Other meniscus derangements
0.892 0.108 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.892 0.108 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.892 0.108 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.889 0.111 0.000
Chapter I Certain infectious and parasitic diseases
0.882 0.118 0.000
K83 Other diseases of biliary tract
0.882 0.118 0.000
H02.4 Ptosis of eyelid
0.881 0.119 0.000
I86 Varicose veins of other sites
0.881 0.119 0.000
M24 Other specific joint derangements
0.881 0.119 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.878 0.122 0.000
S40-S49 Injuries to the shoulder and upper arm
0.872 0.128 0.000
S00.1 Contusion of eyelid and periocular area
0.869 0.131 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.868 0.132 0.000
M25 Other joint disorders, not elsewhere classified
0.867 0.133 0.000
S06 Intracranial injury
0.865 0.135 0.000
K70 Alcoholic liver disease
0.863 0.137 0.000
S02.4 Fracture of malar and maxillary bones
0.861 0.139 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.860 0.140 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.859 0.141 0.000
Y40 Systemic antibiotics
0.856 0.144 0.000
H43-H45 Disorders of vitreous body and globe
0.854 0.146 0.000
H02.5 Other disorders affecting eyelid function
0.853 0.147 0.000
Chapter V Mental and behavioural disorders
0.853 0.147 0.000
Chapter XXII Codes for special purposes
0.852 0.148 0.000
S61 Open wound of wrist and hand
0.851 0.149 0.000
K74 Fibrosis and cirrhosis of liver
0.850 0.150 0.000
S02.10 Fracture of base of skull (closed)
0.850 0.150 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.848 0.152 0.000
K82 Other diseases of gallbladder
0.845 0.155 0.000
I63 Cerebral infarction
0.845 0.155 0.000
K76.9 Liver disease, unspecified
0.845 0.155 0.000
M21.3 Wrist or foot drop (acquired)
0.845 0.155 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.844 0.156 0.000
H40.9 Glaucoma, unspecified
0.839 0.161 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.837 0.163 0.000
S02.2 Fracture of nasal bones
0.836 0.164 0.000
W20-W49 Exposure to inanimate mechanical forces
0.835 0.165 0.000
Chapter X Diseases of the respiratory system
0.832 0.168 0.000
H40.1 Primary open-angle glaucoma
0.831 0.169 0.000
S09 Other and unspecified injuries of head
0.827 0.173 0.000
J09-J18 Influenza and pneumonia
0.827 0.173 0.000
H04 Disorders of lachrymal system
0.827 0.173 0.000
K76.6 Portal hypertension
0.826 0.174 0.000
S68 Traumatic amputation of wrist and hand
0.825 0.175 0.000
I44 Atrioventricular and left bundle-branch block
0.824 0.176 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.823 0.177 0.000
K86.3 Pseudocyst of pancreas
0.821 0.179 0.000
H25-H28 Disorders of lens
0.821 0.179 0.000
H02.9 Disorder of eyelid, unspecified
0.820 0.180 0.000
J18 Pneumonia, organism unspecified
0.819 0.181 0.000
T86 Failure and rejection of transplanted organs and tissues
0.816 0.184 0.000
K86.2 Cyst of pancreas
0.815 0.184 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
K83.8 Other specified diseases of biliary tract
0.813 0.187 0.000
M84 Disorders of continuity of bone
0.812 0.188 0.000
J18.1 Lobar pneumonia, unspecified
0.811 0.189 0.000
S64 Injury of nerves at wrist and hand level
0.809 0.191 0.000
I34.1 Mitral (valve) prolapse
0.805 0.195 0.000
T92 Sequelae of injuries of upper limb
0.805 0.195 0.000
S01 Open wound of head
0.804 0.196 0.000
T79-T79 Certain early complications of trauma
0.804 0.196 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.802 0.198 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.802 0.198 0.000
G90 Disorders of autonomic nervous system
0.800 0.200 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.800 0.200 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.799 0.201 0.000
I81 Portal vein thrombosis
0.798 0.202 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.798 0.202 0.000
S00.7 Multiple superficial injuries of head
0.796 0.204 0.000
G70-G73 Diseases of myoneural junction and muscle
0.796 0.204 0.000
S02.6 Fracture of mandible
0.795 0.205 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.794 0.206 0.000
S80-S89 Injuries to the knee and lower leg
0.793 0.207 0.000
S42 Fracture of shoulder and upper arm
0.792 0.207 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.792 0.208 0.000
H36 Retinal disorders in diseases classified elsewhere
0.789 0.211 0.000
S02.0 Fracture of vault of skull
0.789 0.211 0.000
I86.1 Scrotal varices
0.788 0.211 0.000
K35-K38 Diseases of appendix
0.787 0.213 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.787 0.213 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.787 0.213 0.000
S20-S29 Injuries to the thorax
0.785 0.215 0.000
M25.5 Pain in joint
0.785 0.215 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.785 0.215 0.000
H40.2 Primary angle-closure glaucoma
0.783 0.217 0.000
B95-B98 Bacterial, viral and other infectious agents
0.783 0.217 0.000
M86-M90 Other osteopathies
0.782 0.218 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.781 0.219 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.781 0.219 0.000
K72 Hepatic failure, not elsewhere classified
0.780 0.220 0.000
H04.1 Other disorders of lachrymal gland
0.778 0.222 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.777 0.223 0.000
H02.3 Blepharochalasis
0.777 0.223 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.777 0.223 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.775 0.225 0.000
H18 Other disorders of cornea
0.774 0.226 0.000
M24.1 Other articular cartilage disorders
0.772 0.228 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.771 0.229 0.000
G57.1 Meralgia paraesthetica
0.769 0.231 0.000
W06 Fall involving bed
0.769 0.231 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.769 0.231 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.769 0.231 0.000
G54 Nerve root and plexus disorders
0.768 0.232 0.000
W10 Fall on and from stairs and steps
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.764 0.236 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.763 0.237 0.000
I50 Heart failure
0.763 0.237 0.000
H01 Other inflammation of eyelid
0.763 0.237 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.761 0.238 0.000
G80 Infantile cerebral palsy
0.761 0.239 0.000
I31 Other diseases of pericardium
0.761 0.239 0.000
Y95 Nosocomial condition
0.760 0.240 0.000
A30-A49 Other bacterial diseases
0.758 0.242 0.000
W08 Fall involving other furniture
0.757 0.243 0.000
I88 Nonspecific lymphadenitis
0.757 0.243 0.000
K82.8 Other specified diseases of gallbladder
0.757 0.243 0.000
I80 Phlebitis and thrombophlebitis
0.755 0.245 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.753 0.247 0.000
S60 Superficial injury of wrist and hand
0.753 0.247 0.000
W29 Contact with other powered hand tools and household machinery
0.752 0.248 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.752 0.248 0.000
S02.3 Fracture of orbital floor
0.751 0.248 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.751 0.249 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.750 0.250 0.000
V40-V49 Car occupant injured in transport accident
0.750 0.250 0.000
K83.0 Cholangitis
0.748 0.252 0.000
Y52 Agents primarily affecting the cardiovascular system
0.748 0.252 0.000
V20-V29 Motorcycle rider injured in transport accident
0.745 0.255 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.744 0.256 0.000
K70.9 Alcoholic liver disease, unspecified
0.743 0.257 0.000
W50-W64 Exposure to animate mechanical forces
0.741 0.259 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.740 0.260 0.000
S61.8 Open wound of other parts of wrist and hand
0.740 0.260 0.000
H35 Other retinal disorders
0.738 0.262 0.000
H33 Retinal detachments and breaks
0.738 0.262 0.000
M91-M94 Chondropathies
0.737 0.262 0.000
F30-F39 Mood [affective] disorders
0.737 0.263 0.000
S02.8 Fractures of other skull and facial bones
0.737 0.263 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.733 0.267 0.000
Y40.0 Penicillins
0.732 0.267 0.000
H43 Disorders of vitreous body
0.732 0.267 0.000
I49 Other cardiac arrhythmias
0.731 0.269 0.000
H26 Other cataract
0.731 0.269 0.000
T82.1 Mechanical complication of cardiac electronic device
0.730 0.270 0.000
S67 Crushing injury of wrist and hand
0.729 0.271 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.729 0.271 0.000
M00-M03 Infectious arthropathies
0.729 0.271 0.000
I87 Other disorders of veins
0.728 0.272 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.727 0.273 0.000
S02.20 Fracture of nasal bones (closed)
0.727 0.273 0.000
M21.2 Flexion deformity
0.726 0.274 0.000
T66-T78 Other and unspecified effects of external causes
0.726 0.274 0.000
V80-V89 Other land transport accidents
0.725 0.275 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.725 0.275 0.000
W13 Fall from, out of or through building or structure
0.724 0.276 0.000
I51 Complications and ill-defined descriptions of heart disease
0.723 0.277 0.000
Y40.9 Systemic antibiotic, unspecified
0.721 0.279 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.279 0.000
S02.5 Fracture of tooth
0.719 0.280 0.000
K86.8 Other specified diseases of pancreas
0.718 0.282 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S05 Injury of eye and orbit
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.283 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
J60-J70 Lung diseases due to external agents
0.714 0.286 0.000
W18 Other fall on same level
0.713 0.287 0.000
W17 Other fall from one level to another
0.713 0.287 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.713 0.287 0.000
W15 Fall from cliff
0.713 0.287 0.000
W14 Fall from tree
0.713 0.287 0.000
W12 Fall on and from scaffolding
0.713 0.287 0.000
W11 Fall on and from ladder
0.713 0.287 0.000
W09 Fall involving playground equipment
0.713 0.287 0.000
W05 Fall involving wheelchair
0.713 0.287 0.000
W04 Fall while being carried or supported by other persons
0.713 0.287 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.713 0.287 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.713 0.287 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.713 0.287 0.000
W00 Fall on same level involving ice and snow
0.713 0.287 0.000
B35-B49 Mycoses
0.712 0.288 0.000
Chapter VIII Diseases of the ear and mastoid process
0.712 0.288 0.000
S00.5 Superficial injury of lip and oral cavity
0.711 0.289 0.000
S00.4 Superficial injury of ear
0.711 0.289 0.000
S00.3 Superficial injury of nose
0.711 0.289 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.711 0.289 0.000
I44.7 Left bundle-branch block, unspecified
0.711 0.289 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.711 0.289 0.000
K75 Other inflammatory liver diseases
0.711 0.289 0.000
S00.0 Superficial injury of scalp
0.710 0.289 0.000
H21 Other disorders of iris and ciliary body
0.710 0.290 0.000
M84.0 Malunion of fracture
0.710 0.290 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.709 0.291 0.000
S02.7 Multiple fractures involving skull and facial bones
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
W19.8 Other specified place
0.709 0.291 0.000
W19.5 Trade and service area
0.709 0.291 0.000
W19.0 Home
0.709 0.291 0.000
W19.7 Farm
0.709 0.291 0.000
W19.6 Industrial and construction area
0.709 0.291 0.000
W19.3 Sports and athletics area
0.709 0.291 0.000
W19.1 Residential institution
0.709 0.291 0.000
G91 Hydrocephalus
0.708 0.292 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.708 0.292 0.000
H05 Disorders of orbit
0.707 0.293 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.707 0.293 0.000
K74.0 Hepatic fibrosis
0.707 0.293 0.000
M82 Osteoporosis in diseases classified elsewhere
0.707 0.293 0.000
H40.8 Other glaucoma
0.706 0.294 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.706 0.294 0.000
X60-X84 Intentional self-harm
0.705 0.294 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.705 0.295 0.000
H55-H59 Other disorders of eye and adnexa
0.704 0.295 0.000
S90-S99 Injuries to the ankle and foot
0.703 0.296 0.000
S09.9 Unspecified injury of head
0.703 0.297 0.000
M24.2 Disorder of ligament
0.703 0.297 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.702 0.298 0.000
G82 Paraplegia and tetraplegia
0.701 0.299 0.000
S06.8 Other intracranial injuries
0.699 0.301 0.000
S61.0 Open wound of finger(s) without damage to nail
0.699 0.301 0.000
T82.3 Mechanical complication of other vascular grafts
0.699 0.301 0.000
H36.0 Diabetic retinopathy
0.699 0.301 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.699 0.301 0.000
H16 Keratitis
0.697 0.303 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.697 0.303 0.000
H02.2 Lagophthalmos
0.697 0.303 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.304 0.000
I50.1 Left ventricular failure
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.695 0.305 0.000
M33 Dermatopolymyositis
0.695 0.305 0.000
M32 Systemic lupus erythematosus
0.695 0.305 0.000
M30 Polyarteritis nodosa and related conditions
0.695 0.305 0.000
I61 Intracerebral haemorrhage
0.695 0.305 0.000
I85.0 Oesophageal varices with bleeding
0.695 0.305 0.000
I86.8 Varicose veins of other specified sites
0.694 0.306 0.000
I36 Nonrheumatic tricuspid valve disorders
0.694 0.306 0.000
M81 Osteoporosis without pathological fracture
0.694 0.306 0.000
T85.2 Mechanical complication of intraocular lens
0.693 0.307 0.000
W29.9 Unspecified place
0.693 0.307 0.000
K74.3 Primary biliary cirrhosis
0.693 0.307 0.000
M31 Other necrotising vasculopathies
0.692 0.308 0.000
S65 Injury of blood vessels at wrist and hand level
0.692 0.308 0.000
Y83.9 Surgical procedure, unspecified
0.691 0.309 0.000
G83 Other paralytic syndromes
0.690 0.309 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.690 0.310 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.690 0.310 0.000
H42 Glaucoma in diseases classified elsewhere
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.689 0.311 0.000
H18.8 Other specified disorders of cornea
0.688 0.312 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.688 0.312 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.687 0.313 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.687 0.313 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.687 0.313 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.687 0.313 0.000
I60 Subarachnoid haemorrhage
0.687 0.313 0.000
G81.1 Spastic hemiplegia
0.687 0.313 0.000
G81.0 Flaccid hemiplegia
0.687 0.313 0.000
K76.8 Other specified diseases of liver
0.685 0.315 0.000
K70.3 Alcoholic cirrhosis of liver
0.685 0.315 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.685 0.315 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.684 0.316 0.000
A41 Other septicaemia
0.684 0.316 0.000
M34 Systemic sclerosis
0.684 0.316 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.684 0.316 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.684 0.316 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.684 0.316 0.000
K86.9 Disease of pancreas, unspecified
0.683 0.317 0.000
S12 Fracture of neck
0.682 0.318 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.682 0.318 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.681 0.319 0.000
M25.3 Other instability of joint
0.681 0.319 0.000
G96 Other disorders of central nervous system
0.681 0.319 0.000
S06.4 Epidural haemorrhage
0.681 0.319 0.000
G51 Facial nerve disorders
0.680 0.319 0.000
K77 Liver disorders in diseases classified elsewhere
0.680 0.320 0.000
K73 Chronic hepatitis, not elsewhere classified
0.680 0.320 0.000
K71 Toxic liver disease
0.680 0.320 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.679 0.321 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.678 0.322 0.000
M65-M68 Disorders of synovium and tendon
0.677 0.323 0.000
Y43 Primarily systemic agents
0.677 0.323 0.000
T90 Sequelae of injuries of head
0.677 0.323 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.677 0.323 0.000
H46 Optic neuritis
0.676 0.324 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.676 0.324 0.000
G95 Other diseases of spinal cord
0.675 0.325 0.000
I30 Acute pericarditis
0.674 0.326 0.000
K86.1 Other chronic pancreatitis
0.674 0.326 0.000
V10-V19 Pedal cyclist injured in transport accident
0.674 0.326 0.000
S42.3 Fracture of shaft of humerus
0.674 0.326 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.673 0.327 0.000
K82.4 Cholesterolosis of gallbladder
0.673 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.673 0.327 0.000
I49.1 Atrial premature depolarisation
0.672 0.328 0.000
M22 Disorders of patella
0.672 0.328 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.672 0.328 0.000
Y42.5 Other oestrogens and progestogens
0.671 0.329 0.000
I63.9 Cerebral infarction, unspecified
0.671 0.329 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.671 0.329 0.000
I52 Other heart disorders in diseases classified elsewhere
0.671 0.329 0.000
I48 Atrial fibrillation and flutter
0.671 0.329 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.671 0.329 0.000
I41 Myocarditis in diseases classified elsewhere
0.671 0.329 0.000
I40 Acute myocarditis
0.671 0.329 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.671 0.329 0.000
I37 Pulmonary valve disorders
0.671 0.329 0.000
I32 Pericarditis in diseases classified elsewhere
0.671 0.329 0.000
G23 Other degenerative diseases of basal ganglia
0.671 0.329 0.000
G21 Secondary Parkinsonism
0.671 0.329 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.671 0.329 0.000
G22 Parkinsonism in diseases classified elsewhere
0.671 0.329 0.000
G58 Other mononeuropathies
0.670 0.329 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.670 0.329 0.000
G52 Disorders of other cranial nerves
0.670 0.329 0.000
M23.5 Chronic instability of knee
0.670 0.330 0.000
T91 Sequelae of injuries of neck and trunk
0.669 0.330 0.000
H40.6 Glaucoma secondary to drugs
0.669 0.330 0.000
H40.4 Glaucoma secondary to eye inflammation
0.669 0.330 0.000
H40.3 Glaucoma secondary to eye trauma
0.669 0.330 0.000
K74.6 Other and unspecified cirrhosis of liver
0.669 0.331 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.669 0.331 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.669 0.331 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.669 0.331 0.000
G92 Toxic encephalopathy
0.669 0.331 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.669 0.331 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.669 0.331 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.669 0.331 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.669 0.331 0.000
K76.7 Hepatorenal syndrome
0.669 0.331 0.000
K76.5 Hepatic veno-occlusive disease
0.669 0.331 0.000
K76.4 Peliosis hepatis
0.669 0.331 0.000
K76.3 Infarction of liver
0.669 0.331 0.000
K76.2 Central haemorrhagic necrosis of liver
0.669 0.331 0.000
K76.1 Chronic passive congestion of liver
0.669 0.331 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.669 0.331 0.000
S62 Fracture at wrist and hand level
0.669 0.331 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.668 0.332 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.667 0.333 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.333 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.667 0.333 0.000
Y40.8 Other systemic antibiotics
0.667 0.333 0.000
S06.0 Concussion
0.667 0.333 0.000
K70.1 Alcoholic hepatitis
0.666 0.334 0.000
J10 Influenza due to identified influenza virus
0.664 0.336 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.336 0.000
M24.5 Contracture of joint
0.663 0.336 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.663 0.337 0.000
M24.0 Loose body in joint
0.662 0.337 0.000
G25 Other extrapyramidal and movement disorders
0.662 0.338 0.000
I67 Other cerebrovascular diseases
0.662 0.338 0.000
S70-S79 Injuries to the hip and thigh
0.661 0.338 0.000
H40.0 Glaucoma suspect
0.661 0.339 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.659 0.341 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.659 0.341 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.659 0.341 0.000
M23.9 Internal derangement of knee, unspecified
0.659 0.341 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.659 0.341 0.000
M23.1 Discoid meniscus (congenital)
0.659 0.341 0.000
M23.0 Cystic meniscus
0.659 0.341 0.000
K37 Unspecified appendicitis
0.659 0.341 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.658 0.342 0.000
T86.0 Bone-marrow transplant rejection
0.657 0.343 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.657 0.343 0.000
G57.5 Tarsal tunnel syndrome
0.657 0.343 0.000
G57.4 Lesion of medial popliteal nerve
0.657 0.343 0.000
G57.3 Lesion of lateral popliteal nerve
0.657 0.343 0.000
G57.2 Lesion of femoral nerve
0.657 0.343 0.000
G57.0 Lesion of sciatic nerve
0.657 0.343 0.000
S51 Open wound of forearm
0.657 0.343 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.657 0.343 0.000
H31 Other disorders of choroid
0.657 0.343 0.000
H30 Chorioretinal inflammation
0.657 0.343 0.000
G90.2 Horner's syndrome
0.657 0.343 0.000
H34 Retinal vascular occlusions
0.656 0.344 0.000
S02.60 Fracture of mandible (closed)
0.656 0.344 0.000
H40.5 Glaucoma secondary to other eye disorders
0.656 0.344 0.000
B25-B34 Other viral diseases
0.655 0.345 0.000
S06.2 Diffuse brain injury
0.655 0.345 0.000
M85 Other disorders of bone density and structure
0.655 0.345 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.654 0.346 0.000
M40-M43 Deforming dorsopathies
0.654 0.346 0.000
J69 Pneumonitis due to solids and liquids
0.654 0.346 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.654 0.346 0.000
K70.4 Alcoholic hepatic failure
0.654 0.346 0.000
I31.3 Pericardial effusion (noninflammatory)
0.654 0.346 0.000
T92.1 Sequelae of fracture of arm
0.652 0.348 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.652 0.348 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.652 0.348 0.000
M21.9 Acquired deformity of limb, unspecified
0.652 0.348 0.000
M21.8 Other specified acquired deformities of limbs
0.652 0.348 0.000
M21.7 Unequal limb length (acquired)
0.652 0.348 0.000
M21.6 Other acquired deformities of ankle and foot
0.652 0.348 0.000
M21.4 Flat foot [pes planus] (acquired)
0.652 0.348 0.000
M25.8 Other specified joint disorders
0.652 0.348 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.652 0.348 0.000
S64.1 Injury of median nerve at wrist and hand level
0.651 0.348 0.000
S02.11 Fracture of base of skull (open)
0.651 0.349 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.651 0.349 0.000
M25.9 Joint disorder, unspecified
0.650 0.349 0.000
M25.51 Pain in joint (Shoulder region)
0.650 0.350 0.000
K72.9 Hepatic failure, unspecified
0.648 0.352 0.000
U80 Agent resistant to penicillin and related antibiotics
0.647 0.353 0.000
Y86 Sequelae of other accidents
0.647 0.353 0.000
H44 Disorders of globe
0.646 0.353 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.646 0.353 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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