TreeWAS – Variant ID: rs66833356

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
Chapter X Diseases of the respiratory system	0.999	0.001
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.998	0.002
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.997	0.003
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.987	0.013
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.974	0.026
C78.7 Secondary malignant neoplasm of liver	0.969	0.031
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.967	0.033
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.957	0.043
D70-D77 Other diseases of blood and blood-forming organs	0.953	0.047
C79 Secondary malignant neoplasm of other sites	0.945	0.055
J95-J99 Other diseases of the respiratory system	0.945	0.055
J40-J47 Chronic lower respiratory diseases	0.943	0.057
Y43 Primarily systemic agents	0.937	0.063
J09-J18 Influenza and pneumonia	0.937	0.063
Chapter I Certain infectious and parasitic diseases	0.934	0.066
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.933	0.067
J30-J39 Other diseases of upper respiratory tract	0.930	0.070
N13 Obstructive and reflux uropathy	0.929	0.071
N10-N16 Renal tubulo-interstitial diseases	0.929	0.071
Chapter XIV Diseases of the genitourinary system	0.928	0.072
N13.3 Other and unspecified hydronephrosis	0.918	0.082
S60-S69 Injuries to the wrist and hand	0.915	0.085
D73 Diseases of spleen	0.915	0.085
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.912	0.088
J33 Nasal polyp	0.911	0.089
J90-J94 Other diseases of pleura	0.911	0.089
W20-W49 Exposure to inanimate mechanical forces	0.907	0.093
Y43.3 Other antineoplastic drugs	0.903	0.097
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.902	0.098
C80 Malignant neoplasm without specification of site	0.896	0.104
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.893	0.107
Chapter XII Diseases of the skin and subcutaneous tissue	0.889	0.111
D69 Purpura and other haemorrhagic conditions	0.889	0.111
Q38-Q45 Other congenital malformations of the digestive system	0.889	0.111
J60-J70 Lung diseases due to external agents	0.889	0.111
J33.9 Nasal polyp, unspecified	0.888	0.112
S68 Traumatic amputation of wrist and hand	0.886	0.114
D73.0 Hyposplenism	0.884	0.116
C51-C58 Malignant neoplasms of female genital organs	0.873	0.127
J98 Other respiratory disorders	0.873	0.127
N13.4 Hydroureter	0.871	0.129
X20-X29 Contact with venomous animals and plants	0.871	0.129
D70 Agranulocytosis	0.869	0.131
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.864	0.136
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.862	0.137
N99-N99 Other disorders of the genitourinary system	0.860	0.140
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.850	0.150
S70-S79 Injuries to the hip and thigh	0.847	0.153
A30-A49 Other bacterial diseases	0.846	0.154
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.846	0.154
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.845	0.155
Q80-Q89 Other congenital malformations	0.843	0.157
J90 Pleural effusion, not elsewhere classified	0.836	0.164
J42 Unspecified chronic bronchitis	0.833	0.167
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.833	0.167
Y40 Systemic antibiotics	0.832	0.168
T91 Sequelae of injuries of neck and trunk	0.830	0.170
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.829	0.171
J95 Postprocedural respiratory disorders, not elsewhere classified	0.827	0.173
C78.0 Secondary malignant neoplasm of lung	0.827	0.173
L80-L99 Other disorders of the skin and subcutaneous tissue	0.827	0.173
J40 Bronchitis, not specified as acute or chronic	0.825	0.175
Y52 Agents primarily affecting the cardiovascular system	0.821	0.179
S40-S49 Injuries to the shoulder and upper arm	0.820	0.180
W25 Contact with sharp glass	0.819	0.181
J46 Status asthmaticus	0.816	0.184
D69.6 Thrombocytopenia, unspecified	0.815	0.185
N11 Chronic tubulo-interstitial nephritis	0.812	0.188
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.812	0.188
Y53 Agents primarily affecting the gastro-intestinal system	0.810	0.190
Y41 Other systemic anti-infectives and antiparasitics	0.808	0.192
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.807	0.193
S10-S19 Injuries to the neck	0.806	0.194
C79.9 Secondary malignant neoplasm, unspecified site	0.805	0.195
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.805	0.195
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.804	0.196
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.796	0.204
J43 Emphysema	0.795	0.205
D60-D64 Aplastic and other anaemias	0.795	0.205
J92 Pleural plaque	0.794	0.206
Y51 Drugs primarily affecting the autonomic nervous system	0.791	0.209
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.790	0.210
T36-T50 Poisoning by drugs, medicaments and biological substances	0.789	0.211
X50-X57 Overexertion, travel and privation	0.788	0.212
J33.8 Other polyp of sinus	0.788	0.212
Q60-Q64 Congenital malformations of the urinary system	0.787	0.213
N17-N19 Renal failure	0.786	0.214
V20-V29 Motorcycle rider injured in transport accident	0.786	0.214
C43-C44 Melanoma and other malignant neoplasms of skin	0.785	0.215
J15 Bacterial pneumonia, not elsewhere classified	0.785	0.215
C80.0 Malignant neoplasm, primary site unknown, so stated	0.782	0.218
N13.5 Kinking and stricture of ureter without hydronephrosis	0.780	0.220
L20-L30 Dermatitis and eczema	0.780	0.220
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.780	0.220
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.778	0.222
X23 Contact with hornets, wasps and bees	0.778	0.222
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.776	0.224
J11 Influenza, virus not identified	0.773	0.227
A41 Other septicaemia	0.772	0.228
Y44 Agents primarily affecting blood constituents	0.770	0.230
C79.6 Secondary malignant neoplasm of ovary	0.770	0.230
T20-T25 Burns and corrosions of external body surface, specified by site	0.769	0.231
X60-X84 Intentional self-harm	0.769	0.231
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.768	0.232
B20-B24 Human immunodeficiency virus [HIV] disease	0.767	0.233
Y49 Psychotropic drugs, not elsewhere classified	0.767	0.233
J13 Pneumonia due to Streptococcus pneumoniae	0.766	0.234
Chapter VIII Diseases of the ear and mastoid process	0.765	0.235
L81 Other disorders of pigmentation	0.765	0.235
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.764	0.236
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.764	0.236
J10 Influenza due to identified influenza virus	0.763	0.237
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.763	0.237
T92 Sequelae of injuries of upper limb	0.762	0.238
T79-T79 Certain early complications of trauma	0.761	0.239
J80-J84 Other respiratory diseases principally affecting the interstitium	0.761	0.239
L98.8 Other specified disorders of skin and subcutaneous tissue	0.759	0.241
N99.8 Other postprocedural disorders of genito-urinary system	0.759	0.241
Y46 Antiepileptics and anti-Parkinsonism drugs	0.758	0.242
S69 Other and unspecified injuries of wrist and hand	0.758	0.242
Q00-Q07 Congenital malformations of the nervous system	0.757	0.243
W25.9 Unspecified place	0.756	0.244
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.751	0.249
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.750	0.250
C53 Malignant neoplasm of cervix uteri	0.750	0.250
D63 Anaemia in chronic diseases classified elsewhere	0.749	0.251
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.749	0.251
N25-N29 Other disorders of kidney and ureter	0.749	0.251
B15-B19 Viral hepatitis	0.749	0.251
C55 Malignant neoplasm of uterus, part unspecified	0.748	0.252
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.746	0.254
X10-X19 Contact with heat and hot substances	0.745	0.255
Q85 Phakomatoses, not elsewhere classified	0.745	0.255
T90 Sequelae of injuries of head	0.740	0.260
B25-B34 Other viral diseases	0.740	0.260
J98.4 Other disorders of lung	0.739	0.260
J44 Other chronic obstructive pulmonary disease	0.739	0.261
L85 Other epidermal thickening	0.737	0.263
L81.4 Other melanin hyperpigmentation	0.737	0.263
C91 Lymphoid leukaemia	0.737	0.263
S60 Superficial injury of wrist and hand	0.737	0.263
A41.9 Septicaemia, unspecified	0.735	0.265
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.735	0.265
J32 Chronic sinusitis	0.734	0.266
Q38 Other congenital malformations of tongue, mouth and pharynx	0.730	0.270
C80.9 Malignant neoplasm, unspecified	0.729	0.271
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.726	0.274
W50-W64 Exposure to animate mechanical forces	0.725	0.275
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.725	0.275
D63.0 Anaemia in neoplastic disease	0.724	0.276
H65-H75 Diseases of middle ear and mastoid	0.723	0.277
Q50-Q56 Congenital malformations of genital organs	0.723	0.277
N13.6 Pyonephrosis	0.718	0.282
C54 Malignant neoplasm of corpus uteri	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
Y00-Y09 Assault	0.717	0.283
X85-X99 Assault	0.717	0.283
X58-X59 Accidental exposure to other and unspecified factors	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.717	0.283
W75-W84 Other accidental threats to breathing	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V98-V99 Other and unspecified transport accidents	0.717	0.283
V95-V97 Air and space transport accidents	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V70-V79 Bus occupant injured in transport accident	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
V01-V09 Pedestrian injured in transport accident	0.717	0.283
S72 Fracture of femur	0.716	0.284
Y59 Other and unspecified vaccines and biological substances	0.715	0.284
Y58 Bacterial vaccines	0.715	0.284
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.715	0.284
Y50 Central nervous system stimulants, not elsewhere classified	0.715	0.284
Y48 Anaesthetics and therapeutic gases	0.715	0.284
Y47 Sedatives, hypnotics and antianxiety drugs	0.715	0.284
N19 Unspecified renal failure	0.715	0.285
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.715	0.285
C78.1 Secondary malignant neoplasm of mediastinum	0.715	0.285
Y45.0 Opioids and related analgesics	0.715	0.285
D69.9 Haemorrhagic condition, unspecified	0.714	0.286
T91.3 Sequelae of injury of spinal cord	0.713	0.287
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.712	0.288
X23.9 Unspecified place	0.712	0.288
Y91 Evidence of alcohol involvement determined by level of intoxication	0.711	0.289
C09 Malignant neoplasm of tonsil	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
B90-B94 Sequelae of infectious and parasitic diseases	0.710	0.289
Y40.9 Systemic antibiotic, unspecified	0.710	0.289
B50-B64 Protozoal diseases	0.710	0.290
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.710	0.290
J98.6 Disorders of diaphragm	0.709	0.291
S64 Injury of nerves at wrist and hand level	0.708	0.292
J17 Pneumonia in diseases classified elsewhere	0.708	0.292
Y95 Nosocomial condition	0.708	0.292
N13.9 Obstructive and reflux uropathy, unspecified	0.707	0.293
L98.0 Pyogenic granuloma	0.707	0.293
V40-V49 Car occupant injured in transport accident	0.706	0.294
C43 Malignant melanoma of skin	0.705	0.295
Y60-Y69 Misadventures to patients during surgical and medical care	0.705	0.295
V80-V89 Other land transport accidents	0.703	0.296
C82.1 Mixed small cleaved and large cell, follicular	0.702	0.298
W49 Exposure to other and unspecified inanimate mechanical forces	0.702	0.298
Chapter XXII Codes for special purposes	0.702	0.298
W22 Striking against or struck by other objects	0.701	0.299
Q39 Congenital malformations of oesophagus	0.701	0.299
D69.0 Allergic purpura	0.701	0.299
J98.1 Pulmonary collapse	0.700	0.300
D68 Other coagulation defects	0.699	0.301
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.699	0.301
Q35-Q37 Cleft lip and cleft palate	0.699	0.301
Q30-Q34 Congenital malformations of the respiratory system	0.699	0.301
D80-D89 Certain disorders involving the immune mechanism	0.698	0.302
Chapter VI Diseases of the nervous system	0.698	0.302
S90-S99 Injuries to the ankle and foot	0.697	0.303
Y43.0 Antiallergic and antiemetic drugs	0.696	0.304
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.695	0.305
T91.1 Sequelae of fracture of spine	0.694	0.306
C82.2 Large cell, follicular	0.693	0.307
T33-T35 Frostbite	0.693	0.307
T26-T28 Burns and corrosions confined to eye and internal organs	0.693	0.307
L27 Dermatitis due to substances taken internally	0.691	0.309
Q43 Other congenital malformations of intestine	0.690	0.309
D73.5 Infarction of spleen	0.690	0.310
H72 Perforation of tympanic membrane	0.690	0.310
J43.9 Emphysema, unspecified	0.689	0.311
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.689	0.311
A40 Streptococcal septicaemia	0.689	0.311
C81 Hodgkin's disease	0.688	0.312
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.687	0.313
S40 Superficial injury of shoulder and upper arm	0.687	0.313
J36 Peritonsillar abscess	0.687	0.313
D55-D59 Haemolytic anaemias	0.686	0.314
Y52.4 Angiotensin-converting-enzyme inhibitors	0.686	0.314
D69.3 Idiopathic thrombocytopenic purpura	0.686	0.314
C79.7 Secondary malignant neoplasm of adrenal gland	0.685	0.315
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.685	0.315
B65-B83 Helminthiases	0.684	0.316
D74 Methaemoglobinaemia	0.683	0.317
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.683	0.317
D71 Functional disorders of polymorphonuclear neutrophils	0.683	0.317
C78.4 Secondary malignant neoplasm of small intestine	0.682	0.318
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.682	0.318
N20-N23 Urolithiasis	0.681	0.319
C07 Malignant neoplasm of parotid gland	0.681	0.319
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.681	0.319
J98.0 Diseases of bronchus, not elsewhere classified	0.680	0.319
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.679	0.321
J95.9 Postprocedural respiratory disorder, unspecified	0.678	0.322
C77.5 Intrapelvic lymph nodes	0.678	0.322
S62 Fracture at wrist and hand level	0.678	0.322
A80-A89 Viral infections of the central nervous system	0.678	0.322
J96 Respiratory failure, not elsewhere classified	0.677	0.323
J41 Simple and mucopurulent chronic bronchitis	0.676	0.324
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.676	0.324
Y53.4 Other laxatives	0.676	0.324
L83 Acanthosis nigricans	0.675	0.325
W29 Contact with other powered hand tools and household machinery	0.675	0.325
A41.5 Septicaemia due to other Gram-negative organisms	0.675	0.325
Q85.0 Neurofibromatosis (nonmalignant)	0.675	0.325
Y45.1 Salicylates	0.674	0.325
Q60 Renal agenesis and other reduction defects of kidney	0.673	0.327
S68.0 Traumatic amputation of thumb (complete)(partial)	0.673	0.327
Y43.9 Primarily systemic agent, unspecified	0.672	0.328
Y43.8 Other primarily systemic agents, not elsewhere classified	0.672	0.328
Y43.6 Enzymes, not elsewhere classified	0.672	0.328
Y43.5 Acidifying and alkalising agents	0.672	0.328
Y43.2 Antineoplastic natural products	0.672	0.328
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.672	0.328
L50-L54 Urticaria and erythema	0.672	0.328
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.671	0.328
J12 Viral pneumonia, not elsewhere classified	0.671	0.328
J09 Influenza due to certain identified influenza virus	0.671	0.328
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.671	0.329
J92.0 Pleural plaque with presence of asbestos	0.671	0.329
J69 Pneumonitis due to solids and liquids	0.671	0.329
B85-B89 Pediculosis, acariasis and other infestations	0.669	0.331
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.669	0.331
A75-A79 Rickettsioses	0.669	0.331
A70-A74 Other diseases caused by chlamydiae	0.669	0.331
A65-A69 Other spirochaetal diseases	0.669	0.331
A20-A28 Certain zoonotic bacterial diseases	0.669	0.331
A15-A19 Tuberculosis	0.669	0.331
C77.9 Lymph node, unspecified	0.669	0.331
D67 Hereditary factor IX deficiency	0.669	0.331
D66 Hereditary factor VIII deficiency	0.669	0.331
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.669	0.331
C73 Malignant neoplasm of thyroid gland	0.669	0.331
W21 Striking against or struck by sports equipment	0.668	0.332
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.667	0.332
B99-B99 Other infectious diseases	0.667	0.333
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.667	0.333
N13.7 Vesicoureteral-reflux-associated uropathy	0.666	0.334
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.666	0.334
N15 Other renal tubulo-interstitial diseases	0.666	0.334
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.666	0.334
Y40.3 Macrolides	0.666	0.334
Y54.3 Benzothiadiazine derivatives	0.665	0.335
J30 Vasomotor and allergic rhinitis	0.665	0.335
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.663	0.337
Y43.1 Antineoplastic antimetabolites	0.662	0.337
C79.2 Secondary malignant neoplasm of skin	0.662	0.338
C82.0 Small cleaved cell, follicular	0.662	0.338
C64-C68 Malignant neoplasms of urinary tract	0.662	0.338
T66-T78 Other and unspecified effects of external causes	0.660	0.340
D37-D48 Neoplasms of uncertain or unknown behaviour	0.660	0.340
L85.9 Epidermal thickening, unspecified	0.659	0.341
Chapter IV Endocrine, nutritional and metabolic diseases	0.659	0.341
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.658	0.342
T98 Sequelae of other and unspecified effects of external causes	0.658	0.342
C50-C50 Malignant neoplasm of breast	0.657	0.343
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.657	0.343
J67 Hypersensitivity pneumonitis due to organic dust	0.656	0.343
S65 Injury of blood vessels at wrist and hand level	0.656	0.344
D73.9 Disease of spleen, unspecified	0.656	0.344
D73.8 Other diseases of spleen	0.656	0.344
D73.4 Cyst of spleen	0.656	0.344
D73.3 Abscess of spleen	0.656	0.344
D73.2 Chronic congestive splenomegaly	0.656	0.344
D73.1 Hypersplenism	0.656	0.344
N11.1 Chronic obstructive pyelonephritis	0.656	0.344
T46 Poisoning by agents primarily affecting the cardiovascular system	0.656	0.344
J11.1 Influenza with other respiratory manifestations, virus not identified	0.655	0.345
C84 Peripheral and cutaneous T-cell lymphomas	0.655	0.345
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.654	0.346
C95 Leukaemia of unspecified cell type	0.654	0.346
C94 Other leukaemias of specified cell type	0.654	0.346
C93 Monocytic leukaemia	0.654	0.346
C86 Other specified types of T/NK-cell lymphoma	0.654	0.346
Y88 Sequelae of surgical and medical care as external cause	0.654	0.346
C90 Multiple myeloma and malignant plasma cell neoplasms	0.654	0.346
J33.1 Polypoid sinus degeneration	0.653	0.346
J95.0 Tracheostomy malfunction	0.653	0.347
S70 Superficial injury of hip and thigh	0.651	0.349
W46 Contact with hypodermic needle	0.650	0.349
W45 Foreign body or object entering through skin	0.650	0.349
W43 Exposure to vibration	0.650	0.349
W42 Exposure to noise	0.650	0.349
W41 Exposure to high-pressure jet	0.650	0.349
W40 Explosion of other materials	0.650	0.349
W39 Discharge of firework	0.650	0.349
W38 Explosion and rupture of other specified pressurised devices	0.650	0.349
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.650	0.349
W36 Explosion and rupture of gas cylinder	0.650	0.349
W35 Explosion and rupture of boiler	0.650	0.349
W34 Discharge from other and unspecified firearms	0.650	0.349
W33 Rifle, shotgun and larger firearm discharge	0.650	0.349
W32 Handgun discharge	0.650	0.349
W31 Contact with other and unspecified machinery	0.650	0.349
W30 Contact with agricultural machinery	0.650	0.349
W28 Contact with powered lawn mower	0.650	0.349
W27 Contact with nonpowered hand tool	0.650	0.349
W26 Contact with knife, sword or dagger	0.650	0.349
W24 Contact with lifting and transmission devices, not elsewhere classified	0.650	0.349
W23 Caught, crushed, jammed or pinched in or between objects	0.650	0.349
W20 Struck by thrown, projected or falling object	0.650	0.350
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.650	0.350
J95.8 Other postprocedural respiratory disorders	0.650	0.350
J91 Pleural effusion in conditions classified elsewhere	0.649	0.351
C05 Malignant neoplasm of palate	0.648	0.352
T15-T19 Effects of foreign body entering through natural orifice	0.648	0.352
T91.8 Sequelae of other specified injuries of neck and trunk	0.648	0.352
B24 Unspecified human immunodeficiency virus [HIV] disease	0.647	0.353
N99.3 Prolapse of vaginal vault after hysterectomy	0.647	0.353
T95 Sequelae of burns, corrosions and frostbite	0.647	0.353
T94 Sequelae of injuries involving multiple and unspecified body regions	0.647	0.353
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.647	0.353
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.647	0.353
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.646	0.354
S72.1 Pertrochanteric fracture	0.646	0.354
S42 Fracture of shoulder and upper arm	0.646	0.354
G90-G99 Other disorders of the nervous system	0.646	0.354
J18 Pneumonia, organism unspecified	0.645	0.355
L95 Vasculitis limited to skin, not elsewhere classified	0.644	0.355
C88 Malignant immunoproliferative diseases	0.644	0.356
Q64 Other congenital malformations of urinary system	0.642	0.358
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.642	0.358
J92.9 Pleural plaque without asbestos	0.641	0.359
J32.9 Chronic sinusitis, unspecified	0.641	0.359
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.639	0.361
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.639	0.361
C53.9 Cervix uteri, unspecified	0.639	0.361
S79 Other and unspecified injuries of hip and thigh	0.639	0.361
Y45.2 Propionic acid derivatives	0.639	0.361
L10-L14 Bullous disorders	0.638	0.362
D69.8 Other specified haemorrhagic conditions	0.638	0.362
D69.4 Other primary thrombocytopenia	0.638	0.362
D69.2 Other nonthrombocytopenic purpura	0.638	0.362
D69.1 Qualitative platelet defects	0.638	0.362
D69.5 Secondary thrombocytopenia	0.637	0.363
Q45 Other congenital malformations of digestive system	0.637	0.363
Q42 Congenital absence, atresia and stenosis of large intestine	0.637	0.363
Q41 Congenital absence, atresia and stenosis of small intestine	0.637	0.363
Q40 Other congenital malformations of upper alimentary tract	0.637	0.363
J70 Respiratory conditions due to other external agents	0.637	0.363
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.637	0.363
J66 Airway disease due to specific organic dust	0.637	0.363
J63 Pneumoconiosis due to other inorganic dusts	0.637	0.363
J62 Pneumoconiosis due to dust containing silica	0.637	0.363
J65 Pneumoconiosis associated with tuberculosis	0.637	0.363
J64 Unspecified pneumoconiosis	0.637	0.363
J60 Coalworker's pneumoconiosis	0.637	0.363
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.636	0.364
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.636	0.364
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.635	0.365
S68.8 Traumatic amputation of other parts of wrist and hand	0.635	0.365
S68.4 Traumatic amputation of hand at wrist level	0.635	0.365
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.635	0.365
S12 Fracture of neck	0.633	0.367
C60-C63 Malignant neoplasms of male genital organs	0.633	0.367
T92.9 Sequelae of unspecified injury of upper limb	0.633	0.367
B35-B49 Mycoses	0.632	0.367
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.632	0.368
A50-A64 Infections with a predominantly sexual mode of transmission	0.632	0.368
Y85 Sequelae of transport accidents	0.632	0.368
J98.8 Other specified respiratory disorders	0.632	0.368
L40-L45 Papulosquamous disorders	0.632	0.368
N17 Acute renal failure	0.631	0.369
J37 Chronic laryngitis and laryngotracheitis	0.631	0.369
V10-V19 Pedal cyclist injured in transport accident	0.630	0.369
L89 Decubitus ulcer	0.630	0.370
S71 Open wound of hip and thigh	0.629	0.371
H72.9 Perforation of tympanic membrane, unspecified	0.628	0.371
Q82 Other congenital malformations of skin	0.628	0.372
D72 Other disorders of white blood cells	0.628	0.372
L80 Vitiligo	0.628	0.372
J84 Other interstitial pulmonary diseases	0.627	0.373
J94 Other pleural conditions	0.627	0.373
L27.0 Generalised skin eruption due to drugs and medicaments	0.626	0.374
J98.5 Diseases of mediastinum, not elsewhere classified	0.626	0.374
J98.3 Compensatory emphysema	0.626	0.374
J98.2 Interstitial emphysema	0.626	0.374
C57 Malignant neoplasm of other and unspecified female genital organs	0.626	0.374
C58 Malignant neoplasm of placenta	0.626	0.374
C52 Malignant neoplasm of vagina	0.626	0.374
G70-G73 Diseases of myoneural junction and muscle	0.625	0.375
X29 Contact with unspecified venomous animal or plant	0.624	0.376
X28 Contact with other specified venomous plants	0.624	0.376
X27 Contact with other specified venomous animals	0.624	0.376
X26 Contact with venomous marine animals and plants	0.624	0.376
X25 Contact with other specified venomous arthropods	0.624	0.376
X24 Contact with centipedes and venomous millipedes (tropical)	0.624	0.376
X22 Contact with scorpions	0.624	0.376
X21 Contact with venomous spiders	0.624	0.376
X20 Contact with venomous snakes and lizards	0.624	0.376
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.624	0.376
C97 Malignant neoplasms of independent (primary) multiple sites	0.623	0.377
L98.4 Chronic ulcer of skin, not elsewhere classified	0.622	0.378
S19 Other and unspecified injuries of neck	0.622	0.378
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.621	0.379
N99.4 Postprocedural pelvic peritoneal adhesions	0.621	0.379
S14 Injury of nerves and spinal cord at neck level	0.619	0.380
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.620	0.380
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.619	0.381
Y98 Lifestyle-related condition	0.619	0.381
Y97 Environmental-pollution-related condition	0.619	0.381
Y96 Work-related condition	0.619	0.381
B95-B98 Bacterial, viral and other infectious agents	0.619	0.381
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.618	0.382
Y45.8 Other analgesics and antipyretics	0.618	0.382
Y45.5 4-Aminophenol derivatives	0.618	0.382
Y45.4 Antirheumatics	0.618	0.382
J14 Pneumonia due to Haemophilus influenzae	0.617	0.383
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.616	0.384
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.615	0.384
Q38.7 Pharyngeal pouch	0.615	0.385
C09.9 Tonsil, unspecified	0.615	0.385
T79 Certain early complications of trauma, not elsewhere classified	0.614	0.386
D10-D36 Benign neoplasms	0.614	0.386
L23 Allergic contact dermatitis	0.614	0.386
Q66 Congenital deformities of feet	0.614	0.386
J99 Respiratory disorders in diseases classified elsewhere	0.613	0.387
N28 Other disorders of kidney and ureter, not elsewhere classified	0.612	0.388
C43.4 Malignant melanoma of scalp and neck	0.610	0.390
Y57 Other and unspecified drugs and medicaments	0.610	0.390
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.609	0.390
N99.1 Postprocedural urethral stricture	0.609	0.391
J31.0 Chronic rhinitis	0.609	0.391
S41 Open wound of shoulder and upper arm	0.608	0.392
S67 Crushing injury of wrist and hand	0.608	0.392
S78 Traumatic amputation of hip and thigh	0.608	0.392
S77 Crushing injury of hip and thigh	0.608	0.392
S76 Injury of muscle and tendon at hip and thigh level	0.608	0.392
S75 Injury of blood vessels at hip and thigh level	0.608	0.392
S74 Injury of nerves at hip and thigh level	0.608	0.392
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.608	0.392
C02 Malignant neoplasm of other and unspecified parts of tongue	0.608	0.392
Y44.2 Anticoagulants	0.607	0.393
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.607	0.393
Q44.6 Cystic disease of liver	0.607	0.393

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations